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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4344931
log Bayes Factor = 0.0127891
Chromosome 2   position 241,818,527  (GRCh37) Explore rs4344931 on Ensembl!
Variant rs4344931 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M81.99 Osteoporosis, unspecified (Site unspecified)
0.110 0.890 0.000
M81.9 Osteoporosis, unspecified
0.093 0.907 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.090 0.910 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.074 0.926 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.074 0.926 0.000
G56.0 Carpal tunnel syndrome
0.000 0.926 0.074
M81.92 Osteoporosis, unspecified (Upper arm)
0.067 0.933 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.066 0.934 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.061 0.939 0.000
M81.98 Osteoporosis, unspecified (Other)
0.059 0.941 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.059 0.941 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.051 0.949 0.000
M81 Osteoporosis without pathological fracture
0.045 0.955 0.000
M81.8 Other osteoporosis
0.036 0.964 0.000
M81.1 Postoophorectomy osteoporosis
0.035 0.965 0.000
M81.6 Localised osteoporosis [Lequesne]
0.033 0.967 0.000
M81.5 Idiopathic osteoporosis
0.033 0.967 0.000
M81.4 Drug-induced osteoporosis
0.031 0.969 0.000
M81.0 Postmenopausal osteoporosis
0.031 0.969 0.000
C83.3 Large cell (diffuse)
0.000 0.969 0.031
G56 Mononeuropathies of upper limb
0.000 0.970 0.030
M81.2 Osteoporosis of disuse
0.030 0.970 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.971 0.029
M81.80 Other osteoporosis (Multiple sites)
0.029 0.971 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.029 0.971 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.028 0.972 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.972 0.028
M81.49 Drug-induced osteoporosis (Site unspecified)
0.026 0.973 0.000
M81.89 Other osteoporosis (Site unspecified)
0.026 0.974 0.000
M81.88 Other osteoporosis (Other)
0.026 0.974 0.000
M81.87 Other osteoporosis (Ankle and foot)
0.026 0.974 0.000
M81.86 Other osteoporosis (Lower leg)
0.026 0.974 0.000
M81.85 Other osteoporosis (Pelvic region and thigh)
0.026 0.974 0.000
M81.84 Other osteoporosis (Hand)
0.026 0.974 0.000
M81.83 Other osteoporosis (Forearm)
0.026 0.974 0.000
M81.82 Other osteoporosis (Upper arm)
0.026 0.974 0.000
M81.81 Other osteoporosis (Shoulder region)
0.026 0.974 0.000
G56.8 Other mononeuropathies of upper limb
0.000 0.974 0.026
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.025 0.974 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.025 0.974 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.025 0.974 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.025 0.974 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.025 0.974 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.025 0.974 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.025 0.974 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.025 0.974 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.025 0.974 0.000
C92.0 Acute myeloid leukaemia
0.000 0.975 0.025
C83.7 Burkitt's tumour
0.000 0.976 0.024
M81.59 Idiopathic osteoporosis (Site unspecified)
0.023 0.976 0.000
M81.58 Idiopathic osteoporosis (Other)
0.023 0.976 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.023 0.976 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.023 0.976 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.023 0.976 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.023 0.976 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.023 0.976 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.023 0.976 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.023 0.976 0.000
M81.50 Idiopathic osteoporosis (Multiple sites)
0.023 0.976 0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.023 0.976 0.000
M81.68 Localized osteoporosis [Lequesne] (Other)
0.023 0.976 0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.023 0.976 0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.023 0.976 0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.023 0.976 0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.023 0.976 0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.023 0.976 0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)
0.023 0.976 0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)
0.023 0.976 0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)
0.023 0.976 0.000
C92 Myeloid leukaemia
0.000 0.976 0.024
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.977 0.023
G56.9 Mononeuropathy of upper limb, unspecified
0.000 0.977 0.023
M81.48 Drug-induced osteoporosis (Other)
0.022 0.977 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.022 0.977 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.022 0.977 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.022 0.977 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.022 0.977 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.022 0.977 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.022 0.977 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.022 0.977 0.000
N81.2 Incomplete uterovaginal prolapse
0.023 0.977 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.022 0.977 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.022 0.977 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.022 0.977 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.022 0.977 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.022 0.977 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.022 0.977 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.022 0.977 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.022 0.977 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.022 0.978 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.022 0.978 0.000
M81.28 Osteoporosis of disuse (Other)
0.022 0.978 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.022 0.978 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.022 0.978 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.022 0.978 0.000
M81.24 Osteoporosis of disuse (Hand)
0.022 0.978 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.022 0.978 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.022 0.978 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.022 0.978 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.978 0.022
C83.6 Undifferentiated (diffuse)
0.000 0.979 0.021
C83.4 Immunoblastic (diffuse)
0.000 0.979 0.021
C83.2 Mixed small and large cell (diffuse)
0.000 0.979 0.021
C83.0 Small cell (diffuse)
0.000 0.979 0.021
C83.1 Small cleaved cell (diffuse)
0.000 0.979 0.021
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.021 0.979 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.979 0.021
G56.3 Lesion of radial nerve
0.000 0.979 0.021
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.021 0.979 0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.021 0.979 0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.021 0.979 0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.021 0.979 0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.021 0.979 0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.021 0.979 0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.021 0.979 0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.021 0.979 0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.021 0.979 0.000
G56.2 Lesion of ulnar nerve
0.000 0.979 0.021
G56.4 Causalgia
0.000 0.980 0.020
C95 Leukaemia of unspecified cell type
0.000 0.980 0.020
C92.5 Acute myelomonocytic leukaemia
0.000 0.981 0.019
C86 Other specified types of T/NK-cell lymphoma
0.000 0.981 0.019
C83.5 Lymphoblastic (diffuse)
0.000 0.981 0.019
M81.20 Osteoporosis of disuse (Multiple sites)
0.019 0.981 0.000
G56.1 Other lesions of median nerve
0.000 0.981 0.019
C92.9 Myeloid leukaemia, unspecified
0.000 0.981 0.019
Y43.3 Other antineoplastic drugs
0.000 0.982 0.018
C81 Hodgkin's disease
0.000 0.982 0.018
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.982 0.018
C95.9 Leukaemia, unspecified
0.000 0.982 0.018
C88 Malignant immunoproliferative diseases
0.000 0.982 0.018
C94 Other leukaemias of specified cell type
0.000 0.982 0.017
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.983 0.017
C92.2 Subacute myeloid leukaemia
0.000 0.983 0.017
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.983 0.017
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.983 0.017
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.983 0.017
C92.3 Myeloid sarcoma
0.000 0.983 0.017
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.017 0.983 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.983 0.017
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.983 0.017
C92.7 Other myeloid leukaemia
0.000 0.983 0.016
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.983 0.017
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.983 0.017
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.984 0.016
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.984 0.016
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.984 0.016
C92.4 Acute promyelocytic leukaemia
0.000 0.984 0.016
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.984 0.016
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.984 0.016
C93 Monocytic leukaemia
0.000 0.984 0.015
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.984 0.015
M80-M85 Disorders of bone density and structure
0.016 0.984 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.984 0.016
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.985 0.015
C81.0 Lymphocytic predominance
0.000 0.985 0.015
C95.7 Other leukaemia of unspecified cell type
0.000 0.985 0.015
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.985 0.015
T42.4 Benzodiazepines
0.000 0.985 0.015
C84.4 Peripheral T-cell lymphoma
0.000 0.986 0.014
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.986 0.014
T43.2 Other and unspecified antidepressants
0.000 0.986 0.014
C81.2 Mixed cellularity
0.000 0.986 0.014
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.986 0.014
C86.4 Blastic NK-cell lymphoma
0.000 0.986 0.014
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.986 0.014
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.986 0.014
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.986 0.014
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.986 0.014
C95.0 Acute leukaemia of unspecified cell type
0.000 0.986 0.014
M85 Other disorders of bone density and structure
0.014 0.986 0.000
C91 Lymphoid leukaemia
0.000 0.986 0.014
M81.40 Drug-induced osteoporosis (Multiple sites)
0.014 0.986 0.000
C81.7 Other Hodgkin's disease
0.000 0.986 0.014
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.986 0.013
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.986 0.013
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.987 0.013
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.987 0.013
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.987 0.013
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.987 0.013
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.987 0.013
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.987 0.013
C81.3 Lymphocytic depletion
0.000 0.987 0.013
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.987 0.013
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.987 0.013
C88.7 Other malignant immunoproliferative diseases
0.000 0.987 0.013
C88.3 Immunoproliferative small intestinal disease
0.000 0.987 0.013
C88.2 Gamma heavy chain disease
0.000 0.987 0.013
C88.1 Alpha heavy chain disease
0.000 0.987 0.013
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.987 0.013
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.987 0.013
C94.7 Other specified leukaemias
0.000 0.987 0.013
C94.5 Acute myelofibrosis
0.000 0.987 0.013
C94.4 Acute panmyelosis
0.000 0.987 0.013
C94.3 Mast cell leukaemia
0.000 0.987 0.013
C94.2 Acute megakaryoblastic leukaemia
0.000 0.987 0.013
C94.1 Chronic erythraemia
0.000 0.987 0.013
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.987 0.013
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.987 0.013
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.987 0.013
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.987 0.013
C84.3 Lymphoepithelioid lymphoma
0.000 0.987 0.013
C84.2 T-zone lymphoma
0.000 0.987 0.013
C84.1 Sezary's diease
0.000 0.987 0.013
C84.0 Mycosis fungoides
0.000 0.987 0.013
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.987 0.012
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.987 0.012
C91.4 Hairy-cell leukaemia
0.000 0.987 0.012
T42.0 Hydantoin derivatives
0.000 0.988 0.012
C82.3 Follicular lymphoma grade IIIa
0.000 0.988 0.012
C81.1 Nodular sclerosis
0.000 0.988 0.012
C84.5 Other and unspecified T-cell lymphomas
0.000 0.988 0.012
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.988 0.012
C96.8 Histiocytic sarcoma
0.000 0.988 0.012
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.988 0.012
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.988 0.012
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.988 0.012
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.988 0.012
C96.3 True histiocytic lymphoma
0.000 0.988 0.012
C96.2 Malignant mast cell tumour
0.000 0.988 0.012
C96.1 Malignant histiocytosis
0.000 0.988 0.012
C96.0 Letterer-Siwe disease
0.000 0.988 0.012
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.988 0.012
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.988 0.012
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.988 0.012
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.988 0.012
T42.2 Succinimides and oxazolidinediones
0.000 0.988 0.012
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.988 0.012
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.988 0.012
T50.7 Analeptics and opioid receptor antagonists
0.000 0.988 0.012
T50.5 Appetite depressants
0.000 0.988 0.012
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.988 0.012
T50.0 Mineralocorticoids and their antagonists
0.000 0.988 0.012
T42.1 Iminostilbenes
0.000 0.988 0.012
T36 Poisoning by systemic antibiotics
0.000 0.988 0.012
T43.9 Psychotropic drug, unspecified
0.000 0.988 0.012
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.988 0.012
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.988 0.012
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.988 0.012
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.988 0.012
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.988 0.012
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.988 0.012
T44.0 Anticholinesterase agents
0.000 0.988 0.012
T50.8 Diagnostic agents
0.000 0.988 0.012
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.988 0.012
M85.6 Other cyst of bone
0.012 0.988 0.000
M85.2 Hyperostosis of skull
0.011 0.989 0.000
C82.0 Small cleaved cell, follicular
0.000 0.989 0.011
C93.9 Monocytic leukaemia, unspecified
0.000 0.989 0.011
C93.7 Other monocytic leukaemia
0.000 0.989 0.011
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.989 0.011
C93.2 Subacute monocytic leukaemia
0.000 0.989 0.011
C93.0 Acute monocytic leukaemia
0.000 0.989 0.011
T50.1 Loop [high-ceiling] diuretics
0.000 0.989 0.011
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.989 0.011
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.989 0.011
C92.1 Chronic myeloid leukaemia
0.000 0.989 0.011
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.989 0.011
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.989 0.011
T46.7 Peripheral vasodilators
0.000 0.989 0.011
T46.1 Calcium-channel blockers
0.000 0.989 0.011
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.989 0.011
M80 Osteoporosis with pathological fracture
0.011 0.989 0.000
M83 Adult osteomalacia
0.011 0.989 0.000
C82.6 Cutaneous follicle centre lymphoma
0.000 0.989 0.011
C82.5 Diffuse follicle centre lymphoma
0.000 0.989 0.011
C82.4 Follicular lymphoma grade IIIb
0.000 0.989 0.011
T43.6 Psychostimulants with abuse potential
0.000 0.989 0.011
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.989 0.011
M85.9 Disorder of bone density and structure, unspecified
0.011 0.989 0.000
T42.3 Barbiturates
0.000 0.989 0.011
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.989 0.011
C85.1 B-cell lymphoma, unspecified
0.000 0.989 0.011
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.989 0.011
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.989 0.011
M85.8 Other specified disorders of bone density and structure
0.011 0.989 0.000
M85.0 Fibrous dysplasia (monostotic)
0.010 0.989 0.000
M82 Osteoporosis in diseases classified elsewhere
0.010 0.990 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.990 0.010
M85.65 Other cyst of bone (Pelvic region and thigh)
0.010 0.990 0.000
M85.5 Aneurysmal bone cyst
0.010 0.990 0.000
M85.3 Osteitis condensans
0.010 0.990 0.000
M85.1 Skeletal fluorosis
0.010 0.990 0.000
C82.2 Large cell, follicular
0.000 0.990 0.010
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.990 0.010
C91.7 Other lymphoid leukaemia
0.000 0.990 0.010
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.990 0.010
C91.3 Prolymphocytic leukaemia
0.000 0.990 0.010
C91.2 Subacute lymphocytic leukaemia
0.000 0.990 0.010
C93.1 Chronic monocytic leukaemia
0.000 0.990 0.010
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.990 0.010
C85.0 Lymphosarcoma
0.000 0.990 0.010
C91.9 Lymphoid leukaemia, unspecified
0.000 0.990 0.010
T49.9 Topical agent, unspecified
0.000 0.990 0.010
T49.8 Other topical agents
0.000 0.990 0.010
T49.7 Dental drugs, topically applied
0.000 0.990 0.010
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.990 0.010
T49.5 Ophthalmological drugs and preparations
0.000 0.990 0.010
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.990 0.010
T49.3 Emollients, demulcents and protectants
0.000 0.990 0.010
T49.2 Local astringents and local detergents
0.000 0.990 0.010
T49.1 Antipruritics
0.000 0.990 0.010
T50.4 Drugs affecting uric acid metabolism
0.000 0.990 0.010
C91.0 Acute lymphoblastic leukaemia
0.000 0.990 0.010
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.990 0.009
M85.67 Other cyst of bone (Ankle and foot)
0.009 0.990 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.990 0.009
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.990 0.009
T48.4 Expectorants
0.000 0.990 0.009
T48.3 Antitussives
0.000 0.990 0.009
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.990 0.009
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.990 0.009
T48.0 Oxytocic drugs
0.000 0.990 0.009
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.990 0.009
M80.5 Idiopathic osteoporosis with pathological fracture
0.009 0.990 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.990 0.009
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.991 0.009
M85.22 Hyperostosis of skull-Upper arm
0.009 0.991 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.991 0.009
T37.5 Antiviral drugs
0.000 0.991 0.009
T37.4 Anthelminthics
0.000 0.991 0.009
T37.3 Other antiprotozoal drugs
0.000 0.991 0.009
T37.1 Antimycobacterial drugs
0.000 0.991 0.009
T37.0 Sulphonamides
0.000 0.991 0.009
M85.4 Solitary bone cyst
0.009 0.991 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.991 0.009
M85.88 Other specified disorders of bone density and structure (Other)
0.009 0.991 0.000
T36.4 Tetracyclines
0.000 0.991 0.009
Z51.1 Chemotherapy session for neoplasm
0.000 0.991 0.009
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.991 0.009
T36.0 Penicillins
0.000 0.991 0.009
T41.5 Therapeutic gases
0.000 0.991 0.009
T41.4 Anaesthetic, unspecified
0.000 0.991 0.009
T41.3 Local anaesthetics
0.000 0.991 0.009
T41.2 Other and unspecified general anaesthetics
0.000 0.991 0.009
T41.1 Intravenous anaesthetics
0.000 0.991 0.009
T41.0 Inhaled anaesthetics
0.000 0.991 0.009
T48.5 Anti-common-cold drugs
0.000 0.991 0.009
M85.20 Hyperostosis of skull-Mult sites
0.009 0.991 0.000
T36.9 Systemic antibiotic, unspecified
0.000 0.991 0.009
T36.8 Other systemic antibiotics
0.000 0.991 0.009
T36.7 Antifungal antibiotics, systemically used
0.000 0.991 0.009
T36.6 Rifamycins
0.000 0.991 0.009
T36.5 Aminoglycosides
0.000 0.991 0.009
T36.2 Chloramphenicol group
0.000 0.991 0.009
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.991 0.009
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.009 0.991 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.009 0.991 0.000
C91.5 Adult T-cell leukaemia
0.000 0.991 0.009
M85.83 Other specified disorders of bone density and structure (Forearm)
0.009 0.991 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.991 0.009
M80.8 Other osteoporosis with pathological fracture
0.009 0.991 0.000
M85.68 Other cyst of bone (Other)
0.008 0.991 0.000
M85.69 Other cyst of bone (Site unspecified)
0.008 0.991 0.000
M85.63 Other cyst of bone (Forearm)
0.008 0.991 0.000
M85.62 Other cyst of bone (Upper arm)
0.008 0.991 0.000
M85.61 Other cyst of bone (Shoulder region)
0.008 0.991 0.000
M85.60 Other cyst of bone (Multiple sites)
0.008 0.991 0.000
M85.29 Hyperostosis of skull-Site unspec
0.008 0.991 0.000
M85.28 Hyperostosis of skull-Other
0.008 0.991 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.008 0.991 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.008 0.991 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.008 0.991 0.000
M85.24 Hyperostosis of skull-Hand
0.008 0.991 0.000
M85.23 Hyperostosis of skull-Forearm
0.008 0.991 0.000
M85.21 Hyperostosis of skull-Shldr region
0.008 0.991 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.008 0.991 0.000
M83.8 Other adult osteomalacia
0.008 0.992 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.008 0.992 0.000
M83.3 Adult osteomalacia due to malnutrition
0.008 0.992 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.008 0.992 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.008 0.992 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.008 0.992 0.000
M83.9 Adult osteomalacia, unspecified
0.008 0.992 0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)
0.008 0.992 0.000
M83.5 Other drug-induced osteomalacia in adults
0.008 0.992 0.000
M83.4 Aluminum bone disease
0.008 0.992 0.000
M83.2 Adult osteomalacia due to malabsorption
0.008 0.992 0.000
M83.0 Puerperal osteomalacia
0.008 0.992 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.008 0.992 0.000
M85.98 Disorder of bone density and structure, unspecified (Other)
0.008 0.992 0.000
C90.1 Plasma cell leukaemia
0.000 0.992 0.008
T36.3 Macrolides
0.000 0.992 0.008
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)
0.008 0.992 0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)
0.008 0.992 0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)
0.008 0.992 0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)
0.008 0.992 0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)
0.008 0.992 0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)
0.008 0.992 0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)
0.008 0.992 0.000
Y43 Primarily systemic agents
0.000 0.992 0.008
C81.9 Hodgkin's disease, unspecified
0.000 0.992 0.008
M85.84 Other specified disorders of bone density and structure (Hand)
0.008 0.992 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.008 0.992 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.008 0.992 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.008 0.992 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.008 0.992 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.008 0.992 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.008 0.992 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.008 0.992 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.008 0.992 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.008 0.992 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.992 0.008
C90.3 Solitary plasmacytoma
0.000 0.992 0.008
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.008 0.992 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.008 0.992 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.008 0.992 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.008 0.992 0.000
M85.66 Other cyst of bone (Lower leg)
0.008 0.992 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.008 0.992 0.000
M85.19 Skeletal fluorosis (Site unspecified)
0.007 0.992 0.000
M85.18 Skeletal fluorosis (Other)
0.007 0.992 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.007 0.992 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.007 0.992 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.007 0.992 0.000
M85.14 Skeletal fluorosis (Hand)
0.007 0.992 0.000
M85.13 Skeletal fluorosis (Forearm)
0.007 0.992 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.007 0.992 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.007 0.992 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.007 0.992 0.000
M85.39 Osteitis condensans (Site unspecified)
0.007 0.992 0.000
M85.38 Osteitis condensans (Other)
0.007 0.992 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.007 0.992 0.000
M85.36 Osteitis condensans (Lower leg)
0.007 0.992 0.000
M85.35 Osteitis condensans (Pelvic region and thigh)
0.007 0.992 0.000
M85.34 Osteitis condensans (Hand)
0.007 0.992 0.000
M85.33 Osteitis condensans (Forearm)
0.007 0.992 0.000
M85.32 Osteitis condensans (Upper arm)
0.007 0.992 0.000
M85.31 Osteitis condensans (Shoulder region)
0.007 0.992 0.000
M85.30 Osteitis condensans (Multiple sites)
0.007 0.992 0.000
M85.59 Aneurysmal bone cyst (Site unspecified)
0.007 0.992 0.000
M85.58 Aneurysmal bone cyst (Other)
0.007 0.992 0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)
0.007 0.992 0.000
M85.56 Aneurysmal bone cyst (Lower leg)
0.007 0.992 0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)
0.007 0.992 0.000
M85.54 Aneurysmal bone cyst (Hand)
0.007 0.992 0.000
M85.53 Aneurysmal bone cyst (Forearm)
0.007 0.992 0.000
M85.52 Aneurysmal bone cyst (Upper arm)
0.007 0.992 0.000
M85.51 Aneurysmal bone cyst (Shoulder region)
0.007 0.992 0.000
M85.50 Aneurysmal bone cyst (Multiple sites)
0.007 0.992 0.000
M83.1 Senile osteomalacia
0.007 0.992 0.000
M85.64 Other cyst of bone (Hand)
0.007 0.992 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.007 0.992 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.007 0.992 0.000
T45.0 Antiallergic and antiemetic drugs
0.000 0.992 0.007
Y43.4 Immunosuppressive agents
0.000 0.992 0.008
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.993 0.007
T45.8 Other primarily systemic and haematological agents
0.000 0.993 0.007
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.993 0.007
T45.6 Fibrinolysis-affecting drugs
0.000 0.993 0.007
T45.5 Anticoagulants
0.000 0.993 0.007
T45.4 Iron and its compounds
0.000 0.993 0.007
T45.3 Enzymes, not elsewhere classified
0.000 0.993 0.007
M43.1 Spondylolisthesis
0.007 0.993 0.000
T47.0 Histamine H(2)-receptor antagonists
0.000 0.993 0.007
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.007 0.993 0.000
M43 Other deforming dorsopathies
0.007 0.993 0.000
T38.0 Glucocorticoids and synthetic analogues
0.000 0.993 0.007
C90.2 Plasmacytoma, extramedullary
0.000 0.993 0.007
M80.0 Postmenopausal osteoporosis with pathological fracture
0.007 0.993 0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)
0.007 0.993 0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)
0.007 0.993 0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)
0.007 0.993 0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)
0.007 0.993 0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)
0.007 0.993 0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)
0.007 0.993 0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)
0.007 0.993 0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)
0.007 0.993 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.993 0.007
T38.7 Androgens and anabolic congeners
0.000 0.993 0.007
T38.4 Oral contraceptives
0.000 0.993 0.007
T38.2 Antithyroid drugs
0.000 0.993 0.007
T47.6 Antidiarrhoeal drugs
0.000 0.993 0.007
T45.2 Vitamins, not elsewhere classified
0.000 0.993 0.007
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.993 0.007
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.993 0.007
T47.7 Emetics
0.000 0.993 0.007
T47.5 Digestants
0.000 0.993 0.007
T47.3 Saline and osmotic laxatives
0.000 0.993 0.007
M85.46 Solitary bone cyst (Lower leg)
0.007 0.993 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.993 0.007
M85.49 Solitary bone cyst (Site unspecified)
0.007 0.993 0.000
M85.48 Solitary bone cyst (Other)
0.007 0.993 0.000
M85.44 Solitary bone cyst (Hand)
0.007 0.993 0.000
M85.43 Solitary bone cyst (Forearm)
0.007 0.993 0.000
M85.42 Solitary bone cyst (Upper arm)
0.007 0.993 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.007 0.993 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.007 0.993 0.000
T38.5 Other oestrogens and progestogens
0.000 0.993 0.007
M82.1 Osteoporosis in endocrine disorders
0.007 0.993 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.993 0.007
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.007 0.993 0.000
T47.4 Other laxatives
0.000 0.993 0.006
M43.19 Spondylolisthesis (Site unspecified)
0.007 0.993 0.000
M80.88 Other osteoporosis with pathological fracture (Other)
0.007 0.993 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.007 0.993 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.006 0.993 0.000
M43.0 Spondylolysis
0.007 0.993 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.006 0.993 0.000
M40.2 Other and unspecified kyphosis
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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