TreeWAS – Variant ID: rs4349008

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
K22 Other diseases of oesophagus	0.999	0.001
S00-S09 Injuries to the head	0.999	0.001
O80-O84 Delivery	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.996	0.004
O80 Single spontaneous delivery	0.993	0.007
K22.1 Ulcer of oesophagus	0.992	0.008
O80.0 Spontaneous vertex delivery	0.989	0.011
K22.7 Barrett's oesophagus	0.988	0.012
K20-K31 Diseases of oesophagus, stomach and duodenum	0.986	0.014
Chapter XI Diseases of the digestive system	0.985	0.015
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.983	0.017
Chapter V Mental and behavioural disorders	0.978	0.022
T36-T50 Poisoning by drugs, medicaments and biological substances	0.978	0.022
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.975	0.025
E65-E68 Obesity and other hyperalimentation	0.960	0.040
K22.4 Dyskinesia of oesophagus	0.953	0.047
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.950	0.050
S06 Intracranial injury	0.948	0.052
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.944	0.056
E66 Obesity	0.942	0.058
S00 Superficial injury of head	0.935	0.065
F40-F48 Neurotic, stress-related and somatoform disorders	0.934	0.066
E66.9 Obesity, unspecified	0.928	0.072
E00-E07 Disorders of thyroid gland	0.928	0.072
S01 Open wound of head	0.925	0.075
F10 Mental and behavioural disorders due to use of alcohol	0.924	0.076
F10.2 Dependence syndrome	0.913	0.087
O20-O29 Other maternal disorders predominantly related to pregnancy	0.911	0.089
S02 Fracture of skull and facial bones	0.909	0.091
S00.8 Superficial injury of other parts of head	0.906	0.094
K22.9 Disease of oesophagus, unspecified	0.904	0.096
E05 Thyrotoxicosis [hyperthyroidism]	0.899	0.101
K70-K77 Diseases of liver	0.898	0.102
E10-E14 Diabetes mellitus	0.896	0.104
S01.8 Open wound of other parts of head	0.891	0.109
K65-K67 Diseases of peritoneum	0.885	0.115
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.883	0.117
O94-O99 Other obstetric conditions, not elsewhere classified	0.871	0.129
S70-S79 Injuries to the hip and thigh	0.871	0.129
F45 Somatoform disorders	0.868	0.132
T20-T25 Burns and corrosions of external body surface, specified by site	0.866	0.134
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.862	0.138
O81 Single delivery by forceps and vacuum extractor	0.859	0.141
Q20-Q28 Congenital malformations of the circulatory system	0.859	0.141
K70 Alcoholic liver disease	0.857	0.143
K21 Gastro-oesophageal reflux disease	0.857	0.143
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.853	0.147
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.853	0.147
E50-E64 Other nutritional deficiencies	0.852	0.148
T66-T78 Other and unspecified effects of external causes	0.849	0.151
E14 Unspecified diabetes mellitus	0.846	0.154
E05.9 Thyrotoxicosis, unspecified	0.844	0.156
O60-O75 Complications of labour and delivery	0.844	0.156
F43 Reaction to severe stress, and adjustment disorders	0.842	0.158
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.840	0.160
K65 Peritonitis	0.839	0.161
S06.2 Diffuse brain injury	0.835	0.165
S10-S19 Injuries to the neck	0.828	0.172
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.827	0.173
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.825	0.175
T46 Poisoning by agents primarily affecting the cardiovascular system	0.824	0.176
O80.9 Single spontaneous delivery, unspecified	0.822	0.178
Q00-Q07 Congenital malformations of the nervous system	0.821	0.179
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.821	0.179
F45.8 Other somatoform disorders	0.821	0.179
F00-F09 Organic, including symptomatic, mental disorders	0.821	0.179
E14.9 Without complications	0.820	0.180
O85-O92 Complications predominantly related to the puerperium	0.818	0.181
Q80-Q89 Other congenital malformations	0.818	0.182
O82 Single delivery by Caesarean section	0.818	0.182
E07 Other disorders of thyroid	0.817	0.183
E40-E46 Malnutrition	0.811	0.189
O20 Haemorrhage in early pregnancy	0.808	0.192
S03 Dislocation, sprain and strain of joints and ligaments of head	0.808	0.192
E05.0 Thyrotoxicosis with diffuse goitre	0.805	0.195
Chapter VIII Diseases of the ear and mastoid process	0.803	0.197
S02.1 Fracture of base of skull	0.796	0.204
Chapter XX External causes of morbidity and mortality	0.792	0.208
O68 Labour and delivery complicated by foetal stress [distress]	0.789	0.211
S06.5 Traumatic subdural haemorrhage	0.787	0.213
K72 Hepatic failure, not elsewhere classified	0.786	0.214
S01.2 Open wound of nose	0.784	0.216
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.779	0.221
K70.3 Alcoholic cirrhosis of liver	0.778	0.222
Q38-Q45 Other congenital malformations of the digestive system	0.777	0.223
S20-S29 Injuries to the thorax	0.775	0.225
K28 Gastrojejunal ulcer	0.774	0.226
S60-S69 Injuries to the wrist and hand	0.773	0.227
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.772	0.228
S06.6 Traumatic subarachnoid haemorrhage	0.772	0.228
K22.3 Perforation of oesophagus	0.771	0.229
T43.0 Tricyclic and tetracyclic antidepressants	0.770	0.230
E10 Insulin-dependent diabetes mellitus	0.767	0.233
S80-S89 Injuries to the knee and lower leg	0.765	0.235
K65.0 Acute peritonitis	0.762	0.238
F41 Other anxiety disorders	0.762	0.238
F10.9 Unspecified mental and behavioural disorder	0.761	0.239
O81.4 Vacuum extractor delivery	0.760	0.240
S02.9 Fracture of skull and facial bones, part unspecified	0.760	0.240
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.759	0.241
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.757	0.243
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.756	0.244
S06.20 Diffuse brain injury (without open intracranial wound)	0.754	0.246
S00.5 Superficial injury of lip and oral cavity	0.754	0.246
S72 Fracture of femur	0.751	0.249
F43.1 Posttraumatic stress disorder	0.751	0.249
S05 Injury of eye and orbit	0.751	0.249
K22.8 Other specified diseases of oesophagus	0.747	0.253
Q23 Congenital malformations of aortic and mitral valves	0.747	0.253
F41.2 Mixed anxiety and depressive disorder	0.745	0.255
S66 Injury of muscle and tendon at wrist and hand level	0.745	0.255
S00.4 Superficial injury of ear	0.744	0.256
S40-S49 Injuries to the shoulder and upper arm	0.742	0.258
K20 Oesophagitis	0.741	0.259
O14.9 Preeclampsia, unspecified	0.741	0.259
K40-K46 Hernia	0.739	0.261
S00.1 Contusion of eyelid and periocular area	0.739	0.261
T43.5 Other and unspecified antipsychotics and neuroleptics	0.737	0.263
E55 Vitamin D deficiency	0.737	0.263
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.736	0.264
S06.0 Concussion	0.735	0.264
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.734	0.266
E07.9 Disorder of thyroid, unspecified	0.731	0.269
F12 Mental and behavioural disorders due to use of cannabinoids	0.730	0.270
T36 Poisoning by systemic antibiotics	0.728	0.271
K70.4 Alcoholic hepatic failure	0.728	0.272
K22.5 Diverticulum of oesophagus, acquired	0.728	0.272
O26 Maternal care for other conditions predominantly related to pregnancy	0.726	0.274
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.726	0.274
Q60-Q64 Congenital malformations of the urinary system	0.725	0.275
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.724	0.276
H60-H62 Diseases of external ear	0.724	0.276
O00-O08 Pregnancy with abortive outcome	0.722	0.278
S09 Other and unspecified injuries of head	0.721	0.278
S32 Fracture of lumbar spine and pelvis	0.721	0.278
E66.0 Obesity due to excess calories	0.719	0.281
S02.0 Fracture of vault of skull	0.718	0.282
K70.1 Alcoholic hepatitis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S08 Traumatic amputation of part of head	0.716	0.284
S07 Crushing injury of head	0.716	0.284
S04 Injury of cranial nerves	0.716	0.284
O84 Multiple delivery	0.715	0.284
O83 Other assisted single delivery	0.715	0.284
S02.10 Fracture of base of skull (closed)	0.715	0.285
S90-S99 Injuries to the ankle and foot	0.713	0.287
O80.1 Spontaneous breech delivery	0.712	0.288
F10.5 Psychotic disorder	0.710	0.290
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.710	0.290
F11 Mental and behavioural disorders due to use of opioids	0.710	0.290
S01.3 Open wound of ear	0.709	0.291
T47.1 Other antacids and anti-gastric-secretion drugs	0.709	0.291
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.708	0.291
K23 Disorders of oesophagus in diseases classified elsewhere	0.707	0.293
S79 Other and unspecified injuries of hip and thigh	0.706	0.293
Q05 Spina bifida	0.706	0.294
K65.9 Peritonitis, unspecified	0.706	0.294
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.706	0.294
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.704	0.295
Q35-Q37 Cleft lip and cleft palate	0.704	0.295
Q30-Q34 Congenital malformations of the respiratory system	0.704	0.295
K73 Chronic hepatitis, not elsewhere classified	0.704	0.296
E66.2 Extreme obesity with alveolar hypoventilation	0.704	0.296
T78 Adverse effects, not elsewhere classified	0.702	0.298
K42 Umbilical hernia	0.702	0.298
S02.3 Fracture of orbital floor	0.702	0.298
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.701	0.299
F70-F79 Mental retardation	0.701	0.299
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.701	0.299
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.701	0.299
T41 Poisoning by anaesthetics and therapeutic gases	0.701	0.299
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.701	0.299
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.701	0.299
S06.3 Focal brain injury	0.701	0.299
F99-F99 Unspecified mental disorder	0.699	0.301
S31 Open wound of abdomen, lower back and pelvis	0.696	0.303
F10.4 Withdrawal state with delirium	0.696	0.304
F43.2 Adjustment disorders	0.693	0.306
O73 Retained placenta and membranes, without haemorrhage	0.692	0.308
O70 Perineal laceration during delivery	0.692	0.308
K25 Gastric ulcer	0.692	0.308
S72.0 Fracture of neck of femur	0.692	0.308
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.691	0.309
O28 Abnormal findings on antenatal screening of mother	0.691	0.309
K72.0 Acute and subacute hepatic failure	0.690	0.310
O23 Infections of genito-urinary tract in pregnancy	0.689	0.311
E67 Other hyperalimentation	0.688	0.312
E68 Sequelae of hyperalimentation	0.688	0.312
O20.9 Haemorrhage in early pregnancy, unspecified	0.688	0.312
O16 Unspecified maternal hypertension	0.687	0.313
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.684	0.316
Q76 Congenital malformations of spine and bony thorax	0.684	0.316
S01.7 Multiple open wounds of head	0.681	0.319
O15 Eclampsia	0.681	0.319
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.681	0.319
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.681	0.319
T23 Burn and corrosion of wrist and hand	0.681	0.319
O03 Spontaneous abortion	0.679	0.321
S06.9 Intracranial injury, unspecified	0.679	0.321
S06.7 Intracranial injury with prolonged coma	0.679	0.321
S06.1 Traumatic cerebral oedema	0.679	0.321
E46 Unspecified protein-energy malnutrition	0.679	0.321
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.677	0.323
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.677	0.323
F18 Mental and behavioural disorders due to use of volatile solvents	0.677	0.323
F16 Mental and behavioural disorders due to use of hallucinogens	0.677	0.323
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.677	0.323
F14 Mental and behavioural disorders due to use of cocaine	0.677	0.323
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.677	0.323
E66.1 Drug-induced obesity	0.675	0.324
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.675	0.325
T46.4 Angiotensin-converting-enzyme inhibitors	0.675	0.325
O14.1 Severe preeclampsia	0.674	0.326
Q50-Q56 Congenital malformations of genital organs	0.674	0.326
F05 Delirium, not induced by alcohol and other psychoactive substances	0.674	0.326
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.673	0.327
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.673	0.327
Chapter XXII Codes for special purposes	0.673	0.327
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.672	0.328
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.671	0.329
S03.2 Dislocation of tooth	0.671	0.329
F48 Other neurotic disorders	0.670	0.330
F44 Dissociative [conversion] disorders	0.670	0.330
S11 Open wound of neck	0.669	0.330
F10.3 Withdrawal state	0.667	0.333
S06.8 Other intracranial injuries	0.666	0.333
S02.2 Fracture of nasal bones	0.666	0.334
O75 Other complications of labour and delivery, not elsewhere classified	0.665	0.335
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.665	0.335
E00 Congenital iodine-deficiency syndrome	0.665	0.335
E02 Subclinical iodine-deficiency hypothyroidism	0.665	0.335
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.663	0.336
F10.8 Other mental and behavioural disorders	0.663	0.337
F10.7 Residual and late-onset psychotic disorder	0.663	0.337
F10.6 Amnesic syndrome	0.663	0.337
T20 Burn and corrosion of head and neck	0.662	0.338
S12 Fracture of neck	0.660	0.340
K42.9 Umbilical hernia without obstruction or gangrene	0.660	0.340
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.659	0.341
T42.4 Benzodiazepines	0.658	0.342
K65.8 Other peritonitis	0.658	0.342
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.658	0.342
T15-T19 Effects of foreign body entering through natural orifice	0.657	0.343
E10.3 With ophthalmic complications	0.656	0.344
Q25 Congenital malformations of great arteries	0.656	0.344
S00.7 Multiple superficial injuries of head	0.655	0.345
E06 Thyroiditis	0.655	0.345
Q65 Congenital deformities of hip	0.655	0.345
Q23.1 Congenital insufficiency of aortic valve	0.654	0.346
E55.9 Vitamin D deficiency, unspecified	0.654	0.346
S02.6 Fracture of mandible	0.654	0.346
O20.0 Threatened abortion	0.654	0.346
Q28 Other congenital malformations of circulatory system	0.653	0.347
O14.0 Moderate preeclampsia	0.653	0.347
K22.0 Achalasia of cardia	0.653	0.347
O29 Complications of anaesthesia during pregnancy	0.653	0.347
O22 Venous complications in pregnancy	0.653	0.347
O25 Malnutrition in pregnancy	0.653	0.347
F80-F89 Disorders of psychological development	0.652	0.348
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.652	0.348
S02.7 Multiple fractures involving skull and facial bones	0.652	0.348
Chapter I Certain infectious and parasitic diseases	0.652	0.348
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.651	0.348
S06.4 Epidural haemorrhage	0.651	0.349
O92 Other disorders of breast and lactation associated with childbirth	0.651	0.349
Q82 Other congenital malformations of skin	0.651	0.349
K27 Peptic ulcer, site unspecified	0.650	0.350
S72.00 Fracture of neck of femur (closed)	0.649	0.351
O21 Excessive vomiting in pregnancy	0.648	0.352
O80.8 Other single spontaneous delivery	0.647	0.353
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.647	0.353
T75 Effects of other external causes	0.646	0.353
F01 Vascular dementia	0.646	0.354
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.646	0.354
V80-V89 Other land transport accidents	0.645	0.355
E05.8 Other thyrotoxicosis	0.645	0.355
E05.5 Thyroid crisis or storm	0.645	0.355
E05.4 Thyrotoxicosis factitia	0.645	0.355
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.645	0.355
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.645	0.355
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.645	0.355
K77 Liver disorders in diseases classified elsewhere	0.644	0.356
K71 Toxic liver disease	0.644	0.356
H60 Otitis externa	0.644	0.356
Q79.8 Other congenital malformations of musculoskeletal system	0.644	0.356
E12 Malnutrition-related diabetes mellitus	0.642	0.358
T21 Burn and corrosion of trunk	0.641	0.359
T68 Hypothermia	0.639	0.361
T43.3 Phenothiazine antipsychotics and neuroleptics	0.638	0.361
E10.6 With other specified complications	0.637	0.362
S81 Open wound of lower leg	0.637	0.363
O82.0 Delivery by elective Caesarean section	0.635	0.364
S00.9 Superficial injury of head, part unspecified	0.635	0.365
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.635	0.365
O42 Premature rupture of membranes	0.635	0.365
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.634	0.365
W20-W49 Exposure to inanimate mechanical forces	0.633	0.367
T43.9 Psychotropic drug, unspecified	0.633	0.367
T43.8 Other psychotropic drugs, not elsewhere classified	0.633	0.367
T43.6 Psychostimulants with abuse potential	0.633	0.367
T43.4 Butyrophenone and thioxanthene neuroleptics	0.633	0.367
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.633	0.367
O87 Venous complications in the puerperium	0.633	0.367
S64 Injury of nerves at wrist and hand level	0.633	0.367
O82.1 Delivery by emergency Caesarean section	0.633	0.367
H65-H75 Diseases of middle ear and mastoid	0.633	0.367
E53 Deficiency of other B group vitamins	0.632	0.368
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.631	0.369
D60-D64 Aplastic and other anaemias	0.631	0.369
S14 Injury of nerves and spinal cord at neck level	0.630	0.370
S32.5 Fracture of pubis	0.630	0.370
X60-X84 Intentional self-harm	0.628	0.372
S42 Fracture of shoulder and upper arm	0.627	0.373
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.627	0.373
K44 Diaphragmatic hernia	0.626	0.374
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.626	0.374
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.626	0.374
B35-B49 Mycoses	0.625	0.375
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.625	0.375
X58-X59 Accidental exposure to other and unspecified factors	0.625	0.375
O71 Other obstetric trauma	0.625	0.375
O97 Death from sequelae of direct obstetric causes	0.625	0.375
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.625	0.375
O95 Obstetric death of unspecified cause	0.625	0.375
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.625	0.375
O61 Failed induction of labour	0.625	0.375
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.625	0.375
S78 Traumatic amputation of hip and thigh	0.624	0.376
S77 Crushing injury of hip and thigh	0.624	0.376
S76 Injury of muscle and tendon at hip and thigh level	0.624	0.376
S75 Injury of blood vessels at hip and thigh level	0.624	0.376
S74 Injury of nerves at hip and thigh level	0.624	0.376
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.624	0.376
Q24 Other congenital malformations of heart	0.623	0.376
Q05.9 Spina bifida, unspecified	0.623	0.377
F45.9 Somatoform disorder, unspecified	0.623	0.377
F45.4 Persistent somatoform pain disorder	0.623	0.377
F45.3 Somatoform autonomic dysfunction	0.623	0.377
F45.2 Hypochondriacal disorder	0.623	0.377
F45.1 Undifferentiated somatoform disorder	0.623	0.377
F45.0 Somatisation disorder	0.623	0.377
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.622	0.377
Q79.6 Ehlers-Danlos syndrome	0.622	0.378
S01.4 Open wound of cheek and temporomandibular area	0.621	0.378
T25 Burn and corrosion of ankle and foot	0.621	0.379
S02.4 Fracture of malar and maxillary bones	0.621	0.379
E66.8 Other obesity	0.621	0.379
T43.2 Other and unspecified antidepressants	0.619	0.381
E13 Other specified diabetes mellitus	0.619	0.381
Y95 Nosocomial condition	0.619	0.381
Q78 Other osteochondrodysplasias	0.618	0.382
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.618	0.382
Q75 Other congenital malformations of skull and face bones	0.618	0.382
Q74 Other congenital malformations of limb(s)	0.618	0.382
Q73 Reduction defects of unspecified limb	0.618	0.382
Q72 Reduction defects of lower limb	0.618	0.382
Q71 Reduction defects of upper limb	0.618	0.382
Q70 Syndactyly	0.618	0.382
Q69 Polydactyly	0.618	0.382
Q68 Other congenital musculoskeletal deformities	0.618	0.382
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.618	0.382
Q43 Other congenital malformations of intestine	0.618	0.382
E61 Deficiency of other nutrient elements	0.618	0.382
T79-T79 Certain early complications of trauma	0.616	0.384
O81.5 Delivery by combination of forceps and vacuum extractor	0.616	0.384
O81.3 Other and unspecified forceps delivery	0.616	0.384
O81.2 Mid-cavity forceps with rotation	0.616	0.384
O81.1 Mid-cavity forceps delivery	0.616	0.384
O81.0 Low forceps delivery	0.616	0.384
Q26 Congenital malformations of great veins	0.616	0.384
Q22 Congenital malformations of pulmonary and tricuspid valves	0.616	0.384
Q20 Congenital malformations of cardiac chambers and connexions	0.616	0.384
K70.2 Alcoholic fibrosis and sclerosis of liver	0.615	0.385
S02.8 Fractures of other skull and facial bones	0.613	0.387
O82.9 Delivery by Caesarean section, unspecified	0.612	0.388
O14.2 HELLP syndrome	0.612	0.388
O44 Placenta praevia	0.611	0.389
E64 Sequelae of malnutrition and other nutritional deficiencies	0.611	0.389
E63 Other nutritional deficiencies	0.611	0.389
E56 Other vitamin deficiencies	0.611	0.389
E51 Thiamine deficiency	0.611	0.389
E50 Vitamin A deficiency	0.611	0.389
E60 Dietary zinc deficiency	0.611	0.389
E59 Dietary selenium deficiency	0.611	0.389
E58 Dietary calcium deficiency	0.611	0.389
E54 Ascorbic acid deficiency	0.611	0.389
E52 Niacin deficiency [pellagra]	0.611	0.389
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.611	0.389
O86 Other puerperal infections	0.611	0.389
O03.9 Complete or unspecified, without complication	0.610	0.390
T78.0 Anaphylactic shock due to adverse food reaction	0.610	0.390
S71 Open wound of hip and thigh	0.610	0.390
O24 Diabetes mellitus in pregnancy	0.609	0.391
T74 Maltreatment syndromes	0.609	0.391
T73 Effects of other deprivation	0.609	0.391
T70 Effects of air pressure and water pressure	0.609	0.391
T69 Other effects of reduced temperature	0.609	0.391
T67 Effects of heat and light	0.609	0.391
T71 Asphyxiation	0.609	0.391
T66 Unspecified effects of radiation	0.609	0.391
K46 Unspecified abdominal hernia	0.609	0.391
Y60-Y69 Misadventures to patients during surgical and medical care	0.608	0.392
K22.2 Oesophageal obstruction	0.607	0.393
S05.9 Injury of eye and orbit, part unspecified	0.607	0.393
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.607	0.393
S27 Injury of other and unspecified intrathoracic organs	0.607	0.393
E14.8 With unspecified complications	0.607	0.393
E14.7 With multiple complications	0.607	0.393
E14.6 With other specified complications	0.607	0.393
E14.5 With peripheral circulatory complications	0.607	0.393
E14.4 With neurological complications	0.607	0.393
E14.2 Withrenal complications	0.607	0.393
E14.1 With ketoacidosis	0.607	0.393
E14.0 With coma	0.607	0.393
O74 Complications of anaesthesia during labour and delivery	0.605	0.395
O65 Obstructed labour due to maternal pelvic abnormality	0.605	0.395
O60 Preterm delivery	0.605	0.395
E07.8 Other specified disorders of thyroid	0.605	0.395
S66.8 Injury of other muscles and tendons at wrist and hand level	0.605	0.395
T39.0 Salicylates	0.604	0.396
F43.9 Reaction to severe stress, unspecified	0.604	0.396
F43.8 Other reactions to severe stress	0.604	0.396
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.604	0.396
V10-V19 Pedal cyclist injured in transport accident	0.603	0.397
E70-E90 Metabolic disorders	0.603	0.397
O46 Antepartum haemorrhage, not elsewhere classified	0.603	0.397
Q85 Phakomatoses, not elsewhere classified	0.603	0.397
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.602	0.397
S37 Injury of urinary and pelvic organs	0.602	0.397
S36 Injury of intra-abdominal organs	0.602	0.397
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.602	0.397
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.602	0.397
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.602	0.397
O20.8 Other haemorrhage in early pregnancy	0.601	0.399
K72.9 Hepatic failure, unspecified	0.601	0.399
S01.1 Open wound of eyelid and periocular area	0.600	0.400
K70.9 Alcoholic liver disease, unspecified	0.600	0.400
S70 Superficial injury of hip and thigh	0.599	0.401
S06.21 Diffuse brain injury (with open intracranial wound)	0.599	0.401
Q27 Other congenital malformations of peripheral vascular system	0.598	0.401
S21 Open wound of thorax	0.598	0.402
Q21 Congenital malformations of cardiac septa	0.596	0.404
M50-M54 Other dorsopathies	0.596	0.404
O70.1 Second degree perineal laceration during delivery	0.594	0.406
M50 Cervical disk disorders	0.594	0.406
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.594	0.406
O03.4 Incomplete, without complication	0.594	0.406
S17 Crushing injury of neck	0.593	0.407
S15 Injury of blood vessels at neck level	0.593	0.407
S18 Traumatic amputation at neck level	0.593	0.407
S16 Injury of muscle and tendon at neck level	0.593	0.407
F60-F69 Disorders of adult personality and behaviour	0.592	0.408
E86 Volume depletion	0.592	0.408
Q60 Renal agenesis and other reduction defects of kidney	0.592	0.408
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.592	0.408
T42.5 Mixed antiepileptics, not elsewhere classified	0.592	0.408
T42.3 Barbiturates	0.592	0.408
T42.2 Succinimides and oxazolidinediones	0.592	0.408
T42.0 Hydantoin derivatives	0.592	0.408
S01.9 Open wound of head, part unspecified	0.592	0.408
S83.2 Tear of meniscus, current	0.592	0.408
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.591	0.409
T46.8 Antivaricose drugs, including sclerosing agents	0.591	0.409
T46.7 Peripheral vasodilators	0.591	0.409
T46.5 Other antihypertensive drugs, not elsewhere classified	0.591	0.409
T46.3 Coronary vasodilators, not elsewhere classified	0.591	0.409
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.591	0.409
T46.1 Calcium-channel blockers	0.591	0.409
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.591	0.409
S10 Superficial injury of neck	0.589	0.411
Q07 Other congenital malformations of nervous system	0.589	0.411
Q06 Other congenital malformations of spinal cord	0.589	0.411
Q04 Other congenital malformations of brain	0.589	0.411
Q03 Congenital hydrocephalus	0.589	0.411
Q01 Encephalocele	0.589	0.411
Q00 Anencephaly and similar malformations	0.589	0.411
Q02 Microcephaly	0.589	0.411
S79.9 Unspecified injury of hip and thigh	0.589	0.411
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.589	0.411
T47.8 Other agents primarily affecting the gastro-intestinal system	0.589	0.411
T47.7 Emetics	0.589	0.411
T47.6 Antidiarrhoeal drugs	0.589	0.411
T47.5 Digestants	0.589	0.411
T47.4 Other laxatives	0.589	0.411
T47.3 Saline and osmotic laxatives	0.589	0.411
T47.2 Stimulant laxatives	0.589	0.411
T47.0 Histamine H(2)-receptor antagonists	0.589	0.411
S22 Fracture of rib(s), sternum and thoracic spine	0.589	0.411
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.589	0.411
F02 Dementia in other diseases classified elsewhere	0.589	0.411
F09 Unspecified organic or symptomatic mental disorder	0.589	0.411
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.589	0.411
T42.1 Iminostilbenes	0.589	0.411
S32.4 Fracture of acetabulum	0.587	0.412

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations