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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4351302
log Bayes Factor = 44.8925
Chromosome 6   position 31,176,921  (GRCh37) Explore rs4351302 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
M45.X9 Ankylosing spondylitis (Site unspecified)
0.997 0.003 0.000
G35 Multiple sclerosis
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.009 0.991
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
E10.1 With ketoacidosis
0.000 0.017 0.983
E16.2 Hypoglycaemia, unspecified
0.000 0.018 0.982
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.018 0.982
E16 Other disorders of pancreatic internal secretion
0.000 0.018 0.982
E00-E07 Disorders of thyroid gland
0.000 0.052 0.948
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.054 0.946
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.075 0.925
M45 Ankylosing spondylitis
0.924 0.076 0.000
E10.2 With renal complications
0.000 0.121 0.879
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.852 0.148 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.151 0.849
E13 Other specified diabetes mellitus
0.000 0.153 0.847
E10.5 With peripheral circulatory complications
0.000 0.159 0.841
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.170 0.830
E10.9 Without complications
0.000 0.170 0.830
M45.X2 Ankylosing spondylitis (Cervical region)
0.826 0.174 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.185 0.815
E06 Thyroiditis
0.000 0.214 0.786
E10.8 With unspecified complications
0.000 0.219 0.781
E14 Unspecified diabetes mellitus
0.000 0.225 0.775
E10.0 With coma
0.000 0.248 0.752
E10.6 With other specified complications
0.000 0.250 0.750
E10.4 With neurological complications
0.000 0.255 0.744
E13.9 Without complications
0.000 0.257 0.743
E05.8 Other thyrotoxicosis
0.000 0.258 0.742
E65-E68 Obesity and other hyperalimentation
0.000 0.268 0.732
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.278 0.721
E14.3 With ophthalmic complications
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.289 0.711
E15 Nondiabetic hypoglycaemic coma
0.000 0.296 0.704
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.296 0.704
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.296 0.704
E16.4 Abnormal secretion of gastrin
0.000 0.296 0.704
E16.3 Increased secretion of glucagon
0.000 0.296 0.704
E40-E46 Malnutrition
0.000 0.302 0.698
E06.9 Thyroiditis, unspecified
0.000 0.310 0.690
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.320 0.680
E00 Congenital iodine-deficiency syndrome
0.000 0.320 0.680
E05.5 Thyroid crisis or storm
0.000 0.322 0.678
E05.4 Thyrotoxicosis factitia
0.000 0.322 0.678
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.322 0.678
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.322 0.678
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.663 0.337 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.663 0.337 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.663 0.337 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.663 0.337 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.663 0.337 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.663 0.337 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.663 0.337 0.000
E14.4 With neurological complications
0.000 0.368 0.632
E16.1 Other hypoglycaemia
0.000 0.376 0.624
E13.8 With unspecified complications
0.000 0.393 0.607
E13.7 With multiple complications
0.000 0.393 0.607
E13.6 With other specified complications
0.000 0.393 0.607
E13.5 With peripheral circulatory complications
0.000 0.393 0.607
E13.4 With neurological complications
0.000 0.393 0.607
E13.3 With ophthalmic complications
0.000 0.393 0.607
E13.2 With renal complications
0.000 0.393 0.607
E13.1 With ketoacidosis
0.000 0.393 0.607
E13.0 With coma
0.000 0.393 0.607
E06.3 Autoimmune thyroiditis
0.000 0.413 0.587
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.583 0.417 0.000
M06.9 Rheumatoid arthritis, unspecified
0.576 0.424 0.000
K90 Intestinal malabsorption
0.000 0.436 0.564
E06.4 Drug-induced thyroiditis
0.000 0.436 0.564
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.436 0.564
E06.1 Subacute thyroiditis
0.000 0.436 0.564
E06.0 Acute thyroiditis
0.000 0.436 0.564
E65 Localised adiposity
0.000 0.443 0.557
E14.8 With unspecified complications
0.000 0.444 0.556
E14.7 With multiple complications
0.000 0.444 0.556
E14.2 Withrenal complications
0.000 0.444 0.556
E14.1 With ketoacidosis
0.000 0.444 0.556
E14.0 With coma
0.000 0.444 0.556
E20-E35 Disorders of other endocrine glands
0.000 0.457 0.543
E50-E64 Other nutritional deficiencies
0.000 0.473 0.527
E67 Other hyperalimentation
0.000 0.475 0.525
E68 Sequelae of hyperalimentation
0.000 0.475 0.525
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.524 0.476 0.000
E14.5 With peripheral circulatory complications
0.000 0.478 0.522
E66 Obesity
0.000 0.481 0.519
E12.9 Without complications
0.000 0.490 0.510
E12.8 With unspecified complications
0.000 0.490 0.510
E12.7 With multiple complications
0.000 0.490 0.510
E12.6 With other specified complications
0.000 0.490 0.510
E12.5 With peripheral circulatory complications
0.000 0.490 0.510
E12.4 With neurological complications
0.000 0.490 0.510
E12.3 With ophthalmic complications
0.000 0.490 0.510
E12.2 With renal complications
0.000 0.490 0.510
E12.1 With ketoacidosis
0.000 0.490 0.510
E12.0 With coma
0.000 0.490 0.510
E14.6 With other specified complications
0.000 0.494 0.505
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.502 0.498 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.500 0.500
E45 Retarded development following protein-energy malnutrition
0.000 0.500 0.500
E43 Unspecified severe protein-energy malnutrition
0.000 0.500 0.500
E42 Marasmic kwashiorkor
0.000 0.500 0.500
E41 Nutritional marasmus
0.000 0.500 0.500
E40 Kwashiorkor
0.000 0.500 0.500
E46 Unspecified protein-energy malnutrition
0.000 0.507 0.493
E11 Non-insulin-dependent diabetes mellitus
0.000 0.508 0.492
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.491 0.508 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.512 0.487
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.512 0.487
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.512 0.487
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.512 0.487
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.512 0.487
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.512 0.487
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.512 0.487
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.512 0.487
E06.5 Other chronic thyroiditis
0.000 0.515 0.484
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.519 0.481
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.527 0.473
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.471 0.529 0.000
M06 Other rheumatoid arthritis
0.470 0.530 0.000
E66.8 Other obesity
0.000 0.541 0.459
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.459 0.541 0.000
E34 Other endocrine disorders
0.000 0.542 0.458
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.450 0.550 0.000
E26 Hyperaldosteronism
0.000 0.557 0.443
K90.9 Intestinal malabsorption, unspecified
0.000 0.563 0.437
E11.3 With ophthalmic complications
0.000 0.563 0.437
E24 Cushing's syndrome
0.000 0.567 0.433
M45-M49 Spondylopathies
0.422 0.578 0.000
E66.0 Obesity due to excess calories
0.000 0.580 0.420
M06.3 Rheumatoid nodule
0.414 0.586 0.000
M06.0 Seronegative rheumatoid arthritis
0.413 0.587 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.588 0.412
K90.3 Pancreatic steatorrhoea
0.000 0.595 0.404
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.595 0.404
K90.1 Tropical sprue
0.000 0.595 0.404
M46 Other inflammatory spondylopathies
0.403 0.597 0.000
E11.5 With peripheral circulatory complications
0.000 0.605 0.395
E34.9 Endocrine disorder, unspecified
0.000 0.606 0.394
E11.8 With unspecified complications
0.000 0.607 0.393
E11.6 With other specified complications
0.000 0.608 0.392
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.391 0.609 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.610 0.389
E32 Diseases of thymus
0.000 0.610 0.389
E31 Polyglandular dysfunction
0.000 0.610 0.389
E30 Disorders of puberty, not elsewhere classified
0.000 0.610 0.389
E25 Adrenogenital disorders
0.000 0.610 0.389
M46.9 Inflammatory spondylopathy, unspecified
0.389 0.611 0.000
M06.34 Rheumatoid nodule (Hand)
0.383 0.617 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.382 0.618 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.622 0.378
E63 Other nutritional deficiencies
0.000 0.622 0.378
E56 Other vitamin deficiencies
0.000 0.622 0.378
E51 Thiamine deficiency
0.000 0.622 0.378
E50 Vitamin A deficiency
0.000 0.622 0.378
E60 Dietary zinc deficiency
0.000 0.622 0.378
E59 Dietary selenium deficiency
0.000 0.622 0.378
E54 Ascorbic acid deficiency
0.000 0.622 0.378
E52 Niacin deficiency [pellagra]
0.000 0.622 0.378
G37 Other demyelinating diseases of central nervous system
0.000 0.623 0.377
E67.8 Other specified hyperalimentation
0.000 0.624 0.376
E67.3 Hypervitaminosis D
0.000 0.624 0.376
E67.2 Megavitamin-B6 syndrome
0.000 0.624 0.376
E67.1 Hypercarotenaemia
0.000 0.624 0.376
E67.0 Hypervitaminosis A
0.000 0.624 0.376
M06.98 Rheumatoid arthritis, unspecified (Other)
0.376 0.624 0.000
E55 Vitamin D deficiency
0.000 0.625 0.375
E20 Hypoparathyroidism
0.000 0.626 0.374
E66.1 Drug-induced obesity
0.000 0.628 0.372
E26.0 Primary hyperaldosteronism
0.000 0.629 0.371
E27 Other disorders of adrenal gland
0.000 0.631 0.369
E22 Hyperfunction of pituitary gland
0.000 0.633 0.367
E29 Testicular dysfunction
0.000 0.634 0.365
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.365 0.635 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.641 0.359
E44.0 Moderate protein-energy malnutrition
0.000 0.641 0.359
E34.0 Carcinoid syndrome
0.000 0.645 0.355
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.646 0.354
E24.9 Cushing's syndrome, unspecified
0.000 0.647 0.353
E58 Dietary calcium deficiency
0.000 0.647 0.353
E11.7 With multiple complications
0.000 0.647 0.353
K90.8 Other intestinal malabsorption
0.000 0.651 0.349
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.654 0.346
G36 Other acute disseminated demyelination
0.000 0.655 0.345
E27.1 Primary adrenocortical insufficiency
0.000 0.659 0.341
M06.8 Other specified rheumatoid arthritis
0.337 0.663 0.000
M06.2 Rheumatoid bursitis
0.337 0.663 0.000
M06.1 Adult-onset Still's disease
0.337 0.663 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.336 0.664 0.000
M06.4 Inflammatory polyarthropathy
0.335 0.665 0.000
E11.1 With ketoacidosis
0.000 0.667 0.333
E24.0 Pituitary-dependent Cushing's disease
0.000 0.670 0.329
E34.5 Androgen resistance syndrome
0.000 0.671 0.329
E34.4 Constitutional tall stature
0.000 0.671 0.329
E34.3 Short stature, not elsewhere classified
0.000 0.671 0.329
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.671 0.329
E34.1 Other hypersecretion of intestinal hormones
0.000 0.671 0.329
E07 Other disorders of thyroid
0.002 0.672 0.327
E61 Deficiency of other nutrient elements
0.000 0.675 0.324
E53 Deficiency of other B group vitamins
0.000 0.677 0.323
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.322 0.678 0.000
E21.0 Primary hyperparathyroidism
0.000 0.678 0.322
M46.2 Osteomyelitis of vertebra
0.321 0.679 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.682 0.317
E26.8 Other hyperaldosteronism
0.000 0.682 0.317
E26.1 Secondary hyperaldosteronism
0.000 0.682 0.317
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.684 0.316
E04 Other non-toxic goitre
0.000 0.687 0.313
E24.8 Other Cushing's syndrome
0.000 0.689 0.310
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.689 0.310
E24.3 Ectopic ACTH syndrome
0.000 0.689 0.310
E24.1 Nelson's syndrome
0.000 0.689 0.310
E22.1 Hyperprolactinaemia
0.000 0.694 0.306
E34.8 Other specified endocrine disorders
0.000 0.695 0.305
M06.37 Rheumatoid nodule (Ankle and foot)
0.303 0.697 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.297 0.703 0.000
M06.38 Rheumatoid nodule (Other)
0.297 0.703 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.297 0.703 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.297 0.703 0.000
M06.33 Rheumatoid nodule (Forearm)
0.297 0.703 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.297 0.703 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.297 0.703 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.297 0.703 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.296 0.704 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.296 0.704 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.296 0.704 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.296 0.704 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.296 0.704 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.296 0.704 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.296 0.704 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.704 0.295
E21.2 Other hyperparathyroidism
0.000 0.704 0.295
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.291 0.708 0.000
M46.8 Other specified inflammatory spondylopathies
0.289 0.711 0.000
M46.5 Other infective spondylopathies
0.289 0.711 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.289 0.711 0.000
M46.0 Spinal enthesopathy
0.289 0.711 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.711 0.289
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.715 0.285
M49 Spondylopathies in diseases classified elsewhere
0.284 0.716 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.721 0.279
E25.8 Other adrenogenital disorders
0.000 0.721 0.279
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.721 0.279
E30.9 Disorder of puberty, unspecified
0.000 0.721 0.279
E30.8 Other disorders of puberty
0.000 0.721 0.279
E30.1 Precocious puberty
0.000 0.721 0.279
E30.0 Delayed puberty
0.000 0.721 0.279
E31.9 Polyglandular dysfunction, unspecified
0.000 0.721 0.279
E31.8 Other polyglandular dysfunction
0.000 0.721 0.279
E31.1 Polyglandular hyperfunction
0.000 0.721 0.279
E31.0 Autoimmune polyglandular failure
0.000 0.721 0.279
E32.9 Disease of thymus, unspecified
0.000 0.721 0.279
E32.8 Other diseases of thymus
0.000 0.721 0.279
E32.1 Abscess of thymus
0.000 0.721 0.279
E32.0 Persistent hyperplasia of thymus
0.000 0.721 0.279
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.721 0.279
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.721 0.279
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.721 0.279
M46.4 Discitis, unspecified
0.279 0.721 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.279 0.721 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.279 0.721 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.279 0.721 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.279 0.721 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.279 0.721 0.000
E11.4 With neurological complications
0.000 0.724 0.276
E11.0 With coma
0.000 0.726 0.273
E50.9 Vitamin A deficiency, unspecified
0.000 0.729 0.271
E50.8 Other manifestations of vitamin A deficiency
0.000 0.729 0.271
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.729 0.271
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.729 0.271
E50.5 Vitamin A deficiency with night blindness
0.000 0.729 0.271
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.729 0.271
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.729 0.271
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.729 0.271
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.729 0.271
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.729 0.271
E51.9 Thiamine deficiency, unspecified
0.000 0.729 0.271
E51.8 Other manifestations of thiamine deficiency
0.000 0.729 0.271
E51.2 Wernicke's encephalopathy
0.000 0.729 0.271
E51.1 Beriberi
0.000 0.729 0.271
E56.9 Vitamin deficiency, unspecified
0.000 0.729 0.271
E56.8 Deficiency of other vitamins
0.000 0.729 0.271
E56.1 Deficiency of vitamin K
0.000 0.729 0.271
E56.0 Deficiency of vitamin E
0.000 0.729 0.271
E63.9 Nutritional deficiency, unspecified
0.000 0.729 0.271
E63.8 Other specified nutritional deficiencies
0.000 0.729 0.271
E63.1 Imbalance of constituents of food intake
0.000 0.729 0.271
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.729 0.271
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.729 0.271
E64.8 Sequelae of other nutritional deficiencies
0.000 0.729 0.271
E64.3 Sequelae of rickets
0.000 0.729 0.271
E64.2 Sequelae of vitamin C deficiency
0.000 0.729 0.271
E64.1 Sequelae of vitamin A deficiency
0.000 0.729 0.271
E64.0 Sequelae of protein-energy malnutrition
0.000 0.729 0.271
G37.5 Concentric sclerosis [Balo]
0.000 0.730 0.270
G37.4 Subacute necrotising myelitis
0.000 0.730 0.270
G37.2 Central pontine myelinolysis
0.000 0.730 0.270
G37.1 Central demyelination of corpus callosum
0.000 0.730 0.270
G37.0 Diffuse sclerosis
0.000 0.730 0.270
E55.0 Rickets, active
0.000 0.731 0.269
E22.0 Acromegaly and pituitary gigantism
0.000 0.731 0.269
E20.8 Other hypoparathyroidism
0.000 0.732 0.268
E20.1 Pseudohypoparathyroidism
0.000 0.732 0.268
E20.0 Idiopathic hypoparathyroidism
0.000 0.732 0.268
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.733 0.267
E55.9 Vitamin D deficiency, unspecified
0.000 0.733 0.267
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.266 0.734 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.735 0.265
E27.0 Other adrenocortical overactivity
0.000 0.735 0.265
E03 Other hypothyroidism
0.039 0.736 0.225
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.263 0.737 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.737 0.263
E22.8 Other hyperfunction of pituitary gland
0.000 0.737 0.263
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.263 0.737 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.263 0.737 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.738 0.262
E29.8 Other testicular dysfunction
0.000 0.738 0.262
E29.0 Testicular hyperfunction
0.000 0.738 0.262
M06.32 Rheumatoid nodule (Upper arm)
0.258 0.741 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.745 0.255
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.253 0.746 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.748 0.252
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.748 0.252
E53.9 Vitamin B deficiency, unspecified
0.000 0.748 0.252
E04.0 Non-toxic diffuse goitre
0.000 0.749 0.251
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.752 0.248
G36.9 Acute disseminated demyelination, unspecified
0.000 0.752 0.247
G36.8 Other specified acute disseminated demyelination
0.000 0.752 0.247
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.752 0.247
G36.0 Neuromyelitis optica [Devic]
0.000 0.752 0.247
M06.19 Adult-onset Still's disease (Site unspecified)
0.242 0.758 0.000
M06.18 Adult-onset Still's disease (Other)
0.242 0.758 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.242 0.758 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.242 0.758 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.242 0.758 0.000
M06.14 Adult-onset Still's disease (Hand)
0.242 0.758 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.242 0.758 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.242 0.758 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.242 0.758 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.242 0.758 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.242 0.758 0.000
M06.28 Rheumatoid bursitis (Other)
0.242 0.758 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.242 0.758 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.242 0.758 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.242 0.758 0.000
M06.24 Rheumatoid bursitis (Hand)
0.242 0.758 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.242 0.758 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.242 0.758 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.242 0.758 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.242 0.758 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.242 0.758 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.242 0.758 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.242 0.758 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.242 0.758 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.242 0.758 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.242 0.758 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.242 0.758 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.242 0.758 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.242 0.758 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.242 0.758 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.240 0.760 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.240 0.760 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.240 0.760 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.240 0.760 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.240 0.760 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.240 0.760 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.240 0.760 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.240 0.760 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.760 0.240
E29.1 Testicular hypofunction
0.000 0.762 0.238
E07.1 Dyshormogenetic goitre
0.001 0.764 0.234
E07.0 Hypersecretion of calcitonin
0.001 0.764 0.234
E61.9 Deficiency of nutrient element, unspecified
0.000 0.767 0.233
E61.8 Deficiency of other specified nutrient elements
0.000 0.767 0.233
E61.7 Deficiency of multiple nutrient elements
0.000 0.767 0.233
E61.6 Vanadium deficiency
0.000 0.767 0.233
E61.5 Molybdenum deficiency
0.000 0.767 0.233
E61.4 Chromium deficiency
0.000 0.767 0.233
E61.3 Manganese deficiency
0.000 0.767 0.233
E61.0 Copper deficiency
0.000 0.767 0.233
E53.1 Pyridoxine deficiency
0.000 0.768 0.232
E53.0 Riboflavin deficiency
0.000 0.768 0.232
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.230 0.769 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.230 0.769 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.230 0.769 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.230 0.769 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.230 0.769 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.230 0.769 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.230 0.769 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.230 0.769 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.230 0.769 0.000
E11.2 With renal complications
0.000 0.773 0.226
E04.8 Other specified non-toxic goitre
0.000 0.776 0.224
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.222 0.778 0.000
E61.2 Magnesium deficiency
0.000 0.780 0.220
E27.8 Other specified disorders of adrenal gland
0.000 0.781 0.219
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.218 0.782 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.207 0.793 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.207 0.793 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.207 0.793 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.207 0.793 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.207 0.793 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.207 0.793 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.207 0.793 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.207 0.793 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.207 0.793 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.207 0.793 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.207 0.793 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.207 0.793 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.207 0.793 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.207 0.793 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.207 0.793 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.207 0.793 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.207 0.793 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.207 0.793 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.207 0.793 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.207 0.793 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.207 0.793 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.207 0.793 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.207 0.793 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.207 0.793 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.207 0.793 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.207 0.793 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.207 0.793 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.207 0.793 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.207 0.793 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.207 0.793 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.207 0.793 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.207 0.793 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.207 0.793 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.207 0.793 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.207 0.793 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.207 0.793 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.207 0.793 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.207 0.793 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.207 0.793 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.207 0.793 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.204 0.796 0.000
M49.4 Neuropathic spondylopathy
0.204 0.796 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.204 0.796 0.000
M49.2 Enterobacterial spondylitis
0.204 0.796 0.000
M49.1 Brucella spondylitis
0.204 0.796 0.000
M49.0 Tuberculosis of spine
0.204 0.796 0.000
M48 Other spondylopathies
0.204 0.796 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.204 0.796 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.200 0.799 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.200 0.799 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.200 0.799 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.200 0.799 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.200 0.799 0.000
M46.42 Discitis, unspecified (Cervical region)
0.200 0.799 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.200 0.799 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.200 0.799 0.000
E27.2 Addisonian crisis
0.000 0.800 0.200
E61.1 Iron deficiency
0.000 0.802 0.198
E23 Hypofunction and other disorders of pituitary gland
0.000 0.804 0.195
E03.5 Myxoedema coma
0.028 0.810 0.162
E03.4 Atrophy of thyroid (acquired)
0.028 0.810 0.162
E03.3 Postinfectious hypothyroidism
0.028 0.810 0.162
E03.1 Congenital hypothyroidism without goitre
0.028 0.810 0.162
E03.0 Congenital hypothyroidism with diffuse goitre
0.028 0.810 0.162
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.188 0.811 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.188 0.811 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.188 0.811 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.188 0.811 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.188 0.811 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.188 0.811 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.188 0.811 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.188 0.811 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.188 0.811 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.187 0.813 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.186 0.814 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.820 0.180
E07.8 Other specified disorders of thyroid
0.002 0.822 0.177
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.825 0.175
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.030 0.835 0.135
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.162 0.838 0.000
E28 Ovarian dysfunction
0.003 0.838 0.159
E03.8 Other specified hypothyroidism
0.030 0.846 0.124
M48.8 Other specified spondylopathies
0.153 0.846 0.000
E23.6 Other disorders of pituitary gland
0.000 0.847 0.153
M48.9 Spondylopathy, unspecified
0.146 0.853 0.000
M48.4 Fatigue fracture of vertebra
0.146 0.853 0.000
M48.3 Traumatic spondylopathy
0.146 0.853 0.000
M48.2 Kissing spine
0.146 0.853 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.146 0.853 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.146 0.853 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.146 0.853 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.146 0.853 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.146 0.853 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.146 0.853 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.146 0.853 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.146 0.853 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.146 0.853 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.146 0.853 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.146 0.853 0.000
M49.19 Brucella spondylitis (Site unspecified)
0.146 0.853 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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