TreeWAS – Variant ID: rs4351339

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O63.1 Prolonged second stage (of labour)	0.000	0.745	0.255
G91.9 Hydrocephalus, unspecified	0.152	0.848	0.000
G91 Hydrocephalus	0.148	0.852	0.000
G90-G99 Other disorders of the nervous system	0.146	0.854	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.143	0.857	0.000
G97.8 Other postprocedural disorders of nervous system	0.143	0.857	0.000
G95 Other diseases of spinal cord	0.130	0.870	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.128	0.872	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.121	0.879	0.000
G93 Other disorders of brain	0.116	0.884	0.000
G93.4 Encephalopathy, unspecified	0.115	0.885	0.000
G91.0 Communicating hydrocephalus	0.114	0.886	0.000
G95.0 Syringomyelia and syringobulbia	0.111	0.889	0.000
G95.9 Disease of spinal cord, unspecified	0.111	0.889	0.000
G91.1 Obstructive hydrocephalus	0.111	0.889	0.000
G91.2 Normal-pressure hydrocephalus	0.108	0.892	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.108	0.892	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.107	0.893	0.000
G95.8 Other specified diseases of spinal cord	0.107	0.893	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.106	0.894	0.000
G94.1 Hydrocephalus in neoplastic disease	0.106	0.894	0.000
G92 Toxic encephalopathy	0.105	0.895	0.000
G93.0 Cerebral cysts	0.103	0.897	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.103	0.897	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.103	0.897	0.000
G90 Disorders of autonomic nervous system	0.102	0.898	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.097	0.903	0.000
G96 Other disorders of central nervous system	0.092	0.908	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.092	0.908	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.092	0.908	0.000
G95.2 Cord compression, unspecified	0.091	0.909	0.000
G91.8 Other hydrocephalus	0.087	0.913	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.085	0.915	0.000
G93.7 Reye's syndrome	0.083	0.917	0.000
G93.5 Compression of brain	0.082	0.918	0.000
G90.2 Horner's syndrome	0.081	0.919	0.000
O63 Long labour	0.000	0.924	0.076
G93.9 Disorder of brain, unspecified	0.075	0.925	0.000
G95.1 Vascular myelopathies	0.073	0.927	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.073	0.927	0.000
G90.8 Other disorders of autonomic nervous system	0.073	0.927	0.000
G90.4 Autonomic dysreflexia	0.073	0.927	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.073	0.927	0.000
G96.0 Cerebrospinal fluid leak	0.073	0.927	0.000
G90.3 Multisystem degeneration	0.072	0.927	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.069	0.930	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.069	0.930	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.068	0.932	0.000
G96.9 Disorder of central nervous system, unspecified	0.066	0.934	0.000
G93.3 Postviral fatigue syndrome	0.063	0.937	0.000
G96.8 Other specified disorders of central nervous system	0.061	0.939	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.059	0.940	0.000
G93.8 Other specified disorders of brain	0.059	0.941	0.000
G93.6 Cerebral oedema	0.058	0.942	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.056	0.943	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.945	0.055
G93.2 Benign intracranial hypertension	0.054	0.946	0.000
O73.0 Retained placenta, without haemorrhage	0.000	0.948	0.052
O73 Retained placenta and membranes, without haemorrhage	0.000	0.950	0.050
G96.1 Disorders of meninges, not elsewhere classified	0.048	0.951	0.000
O60-O75 Complications of labour and delivery	0.000	0.953	0.047
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.957	0.043
I60.9 Subarachnoid haemorrhage, unspecified	0.043	0.957	0.000
O71 Other obstetric trauma	0.000	0.958	0.042
I60 Subarachnoid haemorrhage	0.042	0.958	0.000
I60.8 Other subarachnoid haemorrhage	0.041	0.959	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.040	0.960	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.038	0.962	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.038	0.962	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.962	0.038
O61 Failed induction of labour	0.000	0.963	0.037
O71.4 Obstetric high vaginal laceration alone	0.000	0.963	0.037
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.964	0.036
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.036	0.964	0.000
O74 Complications of anaesthesia during labour and delivery	0.000	0.965	0.035
O71.7 Obstetric haematoma of pelvis	0.000	0.965	0.035
O66 Other obstructed labour	0.000	0.965	0.035
O60 Preterm delivery	0.000	0.966	0.034
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.033	0.967	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.967	0.033
O71.9 Obstetric trauma, unspecified	0.000	0.967	0.033
O63.0 Prolonged first stage (of labour)	0.000	0.968	0.032
O71.8 Other specified obstetric trauma	0.000	0.969	0.031
O72 Postpartum haemorrhage	0.000	0.969	0.031
O63.9 Long labour, unspecified	0.000	0.969	0.031
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.969	0.031
O71.3 Obstetric laceration of cervix	0.000	0.969	0.031
O71.2 Postpartum inversion of uterus	0.000	0.969	0.031
O71.1 Rupture of uterus during labour	0.000	0.969	0.031
O71.0 Rupture of uterus before onset of labour	0.000	0.969	0.031
I60.5 Subarachnoid haemorrhage from vertebral artery	0.030	0.969	0.000
O71.5 Other obstetric injury to pelvic organs	0.000	0.970	0.030
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.971	0.029
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.028	0.971	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.971	0.028
O61.1 Failed instrumental induction of labour	0.000	0.972	0.028
O61.0 Failed medical induction of labour	0.000	0.972	0.028
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.972	0.028
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.028	0.972	0.000
O61.9 Failed induction of labour, unspecified	0.000	0.972	0.027
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.973	0.027
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.973	0.027
O64.5 Obstructed labour due to compound presentation	0.000	0.973	0.027
O64.4 Obstructed labour due to shoulder presentation	0.000	0.973	0.027
O64.3 Obstructed labour due to brow presentation	0.000	0.973	0.027
O64.2 Obstructed labour due to face presentation	0.000	0.973	0.027
O61.8 Other failed induction of labour	0.000	0.973	0.027
O66.4 Failed trial of labour, unspecified	0.000	0.973	0.026
O67.8 Other intrapartum haemorrhage	0.000	0.974	0.026
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.974	0.026
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.974	0.026
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.975	0.025
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.975	0.025
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.975	0.025
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.975	0.025
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.975	0.025
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.975	0.025
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.975	0.025
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.975	0.025
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.975	0.025
O66.9 Obstructed labour, unspecified	0.000	0.975	0.025
O66.8 Other specified obstructed labour	0.000	0.975	0.025
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.975	0.025
O66.1 Obstructed labour due to locked twins	0.000	0.975	0.025
O72.1 Other immediate postpartum haemorrhage	0.000	0.975	0.025
O60.3 Preterm delivery without spontaneous labour	0.000	0.976	0.024
O60.2 Preterm spontaneous labour with term delivery	0.000	0.976	0.024
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.976	0.024
O60.0 Preterm labour without delivery	0.000	0.976	0.024
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.024	0.976	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.976	0.024
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.977	0.023
O72.0 Third-stage haemorrhage	0.000	0.977	0.023
O72.3 Postpartum coagulation defects	0.000	0.977	0.023
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.978	0.022
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.978	0.022
O62 Abnormalities of forces of labour	0.000	0.978	0.022
O64.1 Obstructed labour due to breech presentation	0.000	0.979	0.021
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.979	0.020
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.979	0.020
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.979	0.020
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.979	0.020
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.979	0.020
O65.0 Obstructed labour due to deformed pelvis	0.000	0.979	0.020
S83.2 Tear of meniscus, current	0.020	0.980	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.020	0.980	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.980	0.020
O75.8 Other specified complications of labour and delivery	0.000	0.981	0.019
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.019	0.981	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.019	0.981	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.983	0.017
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.983	0.017
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.983	0.017
O69.3 Labour and delivery complicated by short cord	0.000	0.983	0.017
O75.0 Maternal distress during labour and delivery	0.000	0.983	0.017
O62.1 Secondary uterine inertia	0.000	0.983	0.017
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.983	0.017
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.984	0.016
O75.9 Complication of labour and delivery, unspecified	0.000	0.984	0.016
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.984	0.016
O75.4 Other complications of obstetric surgery and procedures	0.000	0.984	0.016
O75.3 Other infection during labour	0.000	0.984	0.016
O75.1 Shock during or following labour and delivery	0.000	0.984	0.016
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.984	0.016
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.984	0.016
O62.8 Other abnormalities of forces of labour	0.000	0.984	0.016
S83.1 Dislocation of knee	0.016	0.984	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.985	0.015
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.985	0.015
O62.3 Precipitate labour	0.000	0.985	0.015
O62.9 Abnormality of forces of labour, unspecified	0.000	0.985	0.015
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.015	0.985	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.985	0.015
S83.3 Tear of articular cartilage of knee, current	0.014	0.986	0.000
N80.9 Endometriosis, unspecified	0.014	0.986	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.014	0.986	0.000
S83.0 Dislocation of patella	0.014	0.986	0.000
S83.7 Injury to multiple structures of knee	0.013	0.986	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.987	0.013
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.987	0.013
O62.0 Primary inadequate contractions	0.000	0.988	0.012
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.989	0.011
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.989	0.011
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.990	0.010
S83.6 Sprain and strain of other and unspecified parts of knee	0.010	0.990	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
O48 Prolonged pregnancy	0.000	0.990	0.010
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.990	0.010
O62.2 Other uterine inertia	0.000	0.990	0.010
N83.1 Corpus luteum cyst	0.000	0.990	0.010
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.990	0.010
T78.4 Allergy, unspecified	0.009	0.991	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.991	0.009
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.992	0.008
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.992	0.008
G57.6 Lesion of plantar nerve	0.008	0.992	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.007
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.993	0.007
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
K41 Femoral hernia	0.007	0.993	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
S81.0 Open wound of knee	0.007	0.993	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
S81 Open wound of lower leg	0.007	0.993	0.000
T78 Adverse effects, not elsewhere classified	0.007	0.993	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.993	0.007
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.993	0.007
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.993	0.007
S81.8 Open wound of other parts of lower leg	0.006	0.994	0.000
O97 Death from sequelae of direct obstetric causes	0.000	0.994	0.006
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.994	0.006
O95 Obstetric death of unspecified cause	0.000	0.994	0.006
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.994	0.006
O42 Premature rupture of membranes	0.000	0.994	0.006
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.994	0.006
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
S80-S89 Injuries to the knee and lower leg	0.006	0.994	0.000
O43 Placental disorders	0.000	0.994	0.006
O43.1 Malformation of placenta	0.000	0.994	0.006
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.994	0.006
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.006	0.994	0.000
T78.2 Anaphylactic shock, unspecified	0.006	0.994	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.994	0.006
M54.49 Lumbago with sciatica (Site unspecified)	0.006	0.994	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.994	0.006
O24 Diabetes mellitus in pregnancy	0.000	0.994	0.006
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.005	0.994	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.005	0.994	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.005	0.994	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.005	0.994	0.000
O34.3 Maternal care for cervical incompetence	0.000	0.995	0.005
O34.1 Maternal care for tumour of corpus uteri	0.000	0.995	0.005
O34.4 Maternal care for other abnormalities of cervix	0.000	0.995	0.005
T78.9 Adverse effect, unspecified	0.005	0.995	0.000
T78.8 Other adverse effects, not elsewhere classified	0.005	0.995	0.000
J98.1 Pulmonary collapse	0.005	0.995	0.000
T78.3 Angioneurotic oedema	0.005	0.995	0.000
U80.0 Penicillin resistant agent	0.005	0.995	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
S81.9 Open wound of lower leg, part unspecified	0.005	0.995	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.995	0.005
O31 Complications specific to multiple gestation	0.000	0.995	0.005
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.995	0.005
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.005
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.995	0.005
O34.6 Maternal care for abnormality of vagina	0.000	0.995	0.005
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.995	0.005
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.995	0.005
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.995	0.005
O85-O92 Complications predominantly related to the puerperium	0.000	0.995	0.005
S81.7 Multiple open wounds of lower leg	0.005	0.995	0.000
O34.0 Maternal care for congenital malformation of uterus	0.000	0.995	0.005
O96.9 Death from unspecified obstetric cause	0.000	0.995	0.005
O96.1 Death from indirect obstetric cause	0.000	0.995	0.005
O96.0 Death from direct obstetric cause	0.000	0.995	0.005
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.995	0.005
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.995	0.005
O97.0 Death from sequelae of direct obstetric cause	0.000	0.995	0.005
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.995	0.005
O33 Maternal care for known or suspected disproportion	0.000	0.995	0.005
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.995	0.005
O45 Premature separation of placenta [abruptio placentae]	0.000	0.995	0.005
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.995	0.005
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
S88 Traumatic amputation of lower leg	0.005	0.995	0.000
S87 Crushing injury of lower leg	0.005	0.995	0.000
S85 Injury of blood vessels at lower leg level	0.005	0.995	0.000
S84 Injury of nerves at lower leg level	0.005	0.995	0.000
O43.9 Placental disorder, unspecified	0.000	0.995	0.004
O43.2 Morbidly adherent placenta	0.000	0.995	0.004
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.995	0.004
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.995	0.004
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.995	0.004
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.995	0.004
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.995	0.004
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.995	0.004
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.995	0.005
O41 Other disorders of amniotic fluid and membranes	0.000	0.995	0.004
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.004	0.995	0.000
S86 Injury of muscle and tendon at lower leg level	0.004	0.996	0.000
O43.0 Placental transfusion syndromes	0.000	0.996	0.004
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.996	0.004
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.996	0.004
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.996	0.004
T78.1 Other adverse food reactions, not elsewhere classified	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
D62 Acute posthaemorrhagic anaemia	0.000	0.996	0.004
O43.8 Other placental disorders	0.000	0.996	0.004
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O85 Puerperal sepsis	0.000	0.996	0.004
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.004	0.996	0.000
R47.8 Other and unspecified speech disturbances	0.004	0.996	0.000
O87 Venous complications in the puerperium	0.000	0.996	0.004
O87.2 Haemorrhoids in the puerperium	0.000	0.996	0.004
H66.9 Otitis media, unspecified	0.000	0.996	0.004
O89 Complications of anaesthesia during the puerperium	0.000	0.996	0.004
O41.0 Oligohydramnios	0.000	0.996	0.004
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
O91 Infections of breast associated with childbirth	0.000	0.996	0.004
O30 Multiple gestation	0.000	0.996	0.004
U80 Agent resistant to penicillin and related antibiotics	0.004	0.996	0.000
O31.8 Other complications specific to multiple gestation	0.000	0.996	0.004
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.996	0.004
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.996	0.004
O31.0 Papyraceous foetus	0.000	0.996	0.004
C91.1 Chronic lymphocytic leukaemia	0.004	0.996	0.000
O88 Obstetric embolism	0.000	0.996	0.004
L27.0 Generalised skin eruption due to drugs and medicaments	0.004	0.996	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.004	0.996	0.000
M54.4 Lumbago with sciatica	0.004	0.996	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.996	0.003
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.996	0.004
U80.8 Agent resistant to other penicillin-related antibiotic	0.004	0.996	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.996	0.004
O25 Malnutrition in pregnancy	0.000	0.996	0.004
R22.2 Localised swelling, mass and lump, trunk	0.004	0.996	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.004	0.996	0.000
O33.8 Maternal care for disproportion of other origin	0.000	0.996	0.003
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.996	0.003
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.996	0.003
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.996	0.003
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.996	0.003
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.996	0.003
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.996	0.003
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.996	0.003
O33.9 Maternal care for disproportion, unspecified	0.000	0.996	0.003
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.996	0.003
O45.8 Other premature separation of placenta	0.000	0.996	0.003
O45.0 Premature separation of placenta with coagulation defect	0.000	0.996	0.003
O40 Polyhydramnios	0.000	0.996	0.004
S84.9 Injury of unspecified nerve at lower leg level	0.003	0.996	0.000
S84.8 Injury of other nerves at lower leg level	0.003	0.996	0.000
S84.7 Injury of multiple nerves at lower leg level	0.003	0.996	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.003	0.996	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.003	0.996	0.000
S84.0 Injury of tibial nerve at lower leg level	0.003	0.996	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.003	0.996	0.000
S85.8 Injury of other blood vessels at lower leg level	0.003	0.996	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.003	0.996	0.000
S85.5 Injury of popliteal vein	0.003	0.996	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.003	0.996	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.003	0.996	0.000
S85.2 Injury of peroneal artery	0.003	0.996	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.003	0.996	0.000
S85.0 Injury of popliteal artery	0.003	0.996	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.003	0.996	0.000
S87.0 Crushing injury of knee	0.003	0.996	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.003	0.996	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.003	0.996	0.000
S88.0 Traumatic amputation at knee level	0.003	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.996	0.003
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.003	0.996	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.996	0.003
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.996	0.003
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
Z45.2 Adjustment and management of vascular access device	0.003	0.997	0.000
S86.0 Injury of Achilles tendon	0.003	0.997	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.003	0.997	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.003	0.997	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
O45.9 Premature separation of placenta, unspecified	0.000	0.997	0.003
O28 Abnormal findings on antenatal screening of mother	0.000	0.997	0.003
B17.1 Acute hepatitis C	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
O80-O84 Delivery	0.000	0.997	0.003
O22 Venous complications in pregnancy	0.000	0.997	0.003
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.997	0.003
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.000	0.997	0.003
O90 Complications of the puerperium, not elsewhere classified	0.000	0.997	0.003
B35.3 Tinea pedis	0.003	0.997	0.000
O91.1 Abscess of breast associated with childbirth	0.000	0.997	0.003
O87.9 Venous complication in the puerperium, unspecified	0.000	0.997	0.003
O87.3 Cerebral venous thrombosis in the puerperium	0.000	0.997	0.003
O87.1 Deep phlebothrombosis in the puerperium	0.000	0.997	0.003
O23 Infections of genito-urinary tract in pregnancy	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.000	0.997	0.003
O89.8 Other complications of anaesthesia during the puerperium	0.000	0.997	0.003
O89.6 Failed or difficult intubation during the puerperium	0.000	0.997	0.003
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.000	0.997	0.003
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.000	0.997	0.003
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.000	0.997	0.003
O89.1 Cardiac complications of anaesthesia during the puerperium	0.000	0.997	0.003
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.000	0.997	0.003
O41.1 Infection of amniotic sac and membranes	0.000	0.997	0.003
Q87.4 Marfan's syndrome	0.003	0.997	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.000	0.997	0.003
O91.0 Infection of nipple associated with childbirth	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.000	0.997	0.003
O30.8 Other multiple gestation	0.000	0.997	0.003
O30.2 Quadruplet pregnancy	0.000	0.997	0.003
O30.1 Triplet pregnancy	0.000	0.997	0.003
S31.0 Open wound of lower back and pelvis	0.003	0.997	0.000
O44 Placenta praevia	0.000	0.997	0.003
D37.4 Colon	0.003	0.997	0.000
O88.8 Other obstetric embolism	0.000	0.997	0.003
O88.3 Obstetric pyaemic and septic embolism	0.000	0.997	0.003
O88.2 Obstetric blood-clot embolism	0.000	0.997	0.003
O88.1 Amniotic fluid embolism	0.000	0.997	0.003
O88.0 Obstetric air embolism	0.000	0.997	0.003
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.000	0.997	0.003
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.003	0.997	0.000
M54.44 Lumbago with sciatica-Thoracic	0.003	0.997	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.003	0.997	0.000
M54.42 Lumbago with sciatica-Cervical	0.003	0.997	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.003	0.997	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.003	0.997	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.997	0.003
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.997	0.003
O29.6 Failed or difficult intubation during pregnancy	0.000	0.997	0.003
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.997	0.003
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.997	0.003
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.997	0.003
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.997	0.003
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.997	0.003
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.997	0.003
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.997	0.003
S80 Superficial injury of lower leg	0.003	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.003
M54.47 Lumbago with sciatica (Lumbosacral region)	0.003	0.997	0.000
O90.2 Haematoma of obstetric wound	0.000	0.997	0.003
O81 Single delivery by forceps and vacuum extractor	0.000	0.997	0.003
Z47.8 Other specified orthopaedic follow-up care	0.003	0.997	0.000
R21 Rash and other nonspecific skin eruption	0.003	0.997	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
S82.01 Fracture of patella (open)	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.003	0.997	0.000
O86 Other puerperal infections	0.000	0.997	0.003
G01 Meningitis in bacterial diseases classified elsewhere	0.003	0.997	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.997	0.003
U80.1 Methicillin resistant agent	0.003	0.997	0.000
O81.4 Vacuum extractor delivery	0.000	0.997	0.003
D30.3 Bladder	0.003	0.997	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.997	0.003
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.997	0.003
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.997	0.002
S86.00 Unspecified injury of Achilles tendon	0.002	0.997	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.997	0.003
O70 Perineal laceration during delivery	0.000	0.997	0.003
O26.8 Other specified pregnancy-related conditions	0.000	0.997	0.003
O87.8 Other venous complications in the puerperium	0.000	0.997	0.002
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.003	0.997	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.997	0.002
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.997	0.002
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.997	0.002
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.997	0.002
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.997	0.002
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.997	0.002
O46.8 Other antepartum haemorrhage	0.000	0.997	0.003
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.997	0.003
S89.7 Multiple injuries of lower leg	0.002	0.997	0.000
S89.1 Other specified injuries of lower leg	0.002	0.997	0.000
S89.0 Multiple injuries of lower leg	0.002	0.997	0.000
C91 Lymphoid leukaemia	0.003	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.003	0.997	0.000
O83 Other assisted single delivery	0.000	0.997	0.002
O22.9 Venous complication in pregnancy, unspecified	0.000	0.997	0.002
O22.8 Other venous complications in pregnancy	0.000	0.997	0.002
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.997	0.002
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.997	0.002
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.997	0.002
O22.1 Genital varices in pregnancy	0.000	0.997	0.002
O92.7 Other and unspecified disorders of lactation	0.000	0.997	0.002
O92.6 Galactorrhoea	0.000	0.997	0.002
O92.5 Suppressed lactation	0.000	0.997	0.002
O92.4 Hypogalactia	0.000	0.997	0.002
O92.3 Agalactia	0.000	0.997	0.002
O92.0 Retracted nipple associated with childbirth	0.000	0.997	0.002
K76.8 Other specified diseases of liver	0.003	0.997	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.997	0.003
O90.5 Postpartum thyroiditis	0.000	0.997	0.002
O90.4 Postpartum acute renal failure	0.000	0.997	0.002
O90.3 Cardiomyopathy in the puerperium	0.000	0.997	0.002
O92.1 Cracked nipple associated with childbirth	0.000	0.997	0.002
S30.2 Contusion of external genital organs	0.002	0.997	0.000
S80.0 Contusion of knee	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.997	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations