TreeWAS – Variant ID: rs4358616

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.761	0.239
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.825	0.175
K90.3 Pancreatic steatorrhoea	0.000	0.828	0.171
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.828	0.171
K90.1 Tropical sprue	0.000	0.828	0.171
K90.8 Other intestinal malabsorption	0.000	0.837	0.163
E10 Insulin-dependent diabetes mellitus	0.000	0.859	0.141
E10.9 Without complications	0.000	0.862	0.138
E10.6 With other specified complications	0.000	0.872	0.128
E10.5 With peripheral circulatory complications	0.000	0.873	0.127
E10.4 With neurological complications	0.000	0.876	0.124
E10.3 With ophthalmic complications	0.000	0.882	0.118
E10.1 With ketoacidosis	0.000	0.882	0.118
E10.8 With unspecified complications	0.000	0.888	0.112
E10.7 With multiple complications	0.000	0.899	0.101
E10.0 With coma	0.000	0.899	0.101
E10.2 With renal complications	0.000	0.899	0.101
K90.9 Intestinal malabsorption, unspecified	0.000	0.916	0.084
E83 Disorders of mineral metabolism	0.000	0.917	0.083
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.937	0.063
E10-E14 Diabetes mellitus	0.000	0.938	0.062
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.940	0.060
E83.8 Other disorders of mineral metabolism	0.000	0.940	0.060
E83.2 Disorders of zinc metabolism	0.000	0.940	0.060
E83.0 Disorders of copper metabolism	0.000	0.940	0.060
E13 Other specified diabetes mellitus	0.000	0.949	0.051
E12 Malnutrition-related diabetes mellitus	0.000	0.955	0.044
E13.9 Without complications	0.000	0.957	0.043
E83.3 Disorders of phosphorus metabolism	0.000	0.961	0.039
M25.57 Pain in joint (Ankle and foot)	0.000	0.962	0.038
M25.5 Pain in joint	0.000	0.963	0.037
E13.8 With unspecified complications	0.000	0.963	0.036
E13.7 With multiple complications	0.000	0.963	0.036
E13.6 With other specified complications	0.000	0.963	0.036
E13.5 With peripheral circulatory complications	0.000	0.963	0.036
E13.4 With neurological complications	0.000	0.963	0.036
E13.2 With renal complications	0.000	0.963	0.036
E13.1 With ketoacidosis	0.000	0.963	0.036
E13.0 With coma	0.000	0.963	0.036
E13.3 With ophthalmic complications	0.000	0.965	0.035
E70-E90 Metabolic disorders	0.000	0.966	0.034
E88 Other metabolic disorders	0.000	0.966	0.034
E11 Non-insulin-dependent diabetes mellitus	0.000	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.968	0.032
E12.9 Without complications	0.000	0.968	0.032
E12.8 With unspecified complications	0.000	0.968	0.032
E12.7 With multiple complications	0.000	0.968	0.032
E12.6 With other specified complications	0.000	0.968	0.032
E12.5 With peripheral circulatory complications	0.000	0.968	0.032
E12.4 With neurological complications	0.000	0.968	0.032
E12.3 With ophthalmic complications	0.000	0.968	0.032
E12.2 With renal complications	0.000	0.968	0.032
E12.1 With ketoacidosis	0.000	0.968	0.032
E12.0 With coma	0.000	0.968	0.032
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.968	0.032
M25.52 Pain in joint (Upper arm)	0.000	0.969	0.031
M25.58 Pain in joint (Other)	0.000	0.970	0.030
M25.51 Pain in joint (Shoulder region)	0.000	0.970	0.030
E14 Unspecified diabetes mellitus	0.000	0.970	0.030
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.971	0.029
E14.3 With ophthalmic complications	0.000	0.972	0.028
E11.2 With renal complications	0.000	0.972	0.028
E83.4 Disorders of magnesium metabolism	0.000	0.972	0.027
E16 Other disorders of pancreatic internal secretion	0.000	0.973	0.027
E11.0 With coma	0.000	0.973	0.027
M25.53 Pain in joint (Forearm)	0.000	0.973	0.027
E88.8 Other specified metabolic disorders	0.000	0.973	0.027
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.973	0.027
E11.4 With neurological complications	0.000	0.973	0.027
E88.2 Lipomatosis, not elsewhere classified	0.000	0.973	0.026
E16.2 Hypoglycaemia, unspecified	0.000	0.974	0.026
M25.54 Pain in joint (Hand)	0.000	0.974	0.026
E40-E46 Malnutrition	0.000	0.974	0.026
E85 Amyloidosis	0.000	0.974	0.026
E88.3 Tumour lysis syndrome	0.000	0.974	0.025
E11.1 With ketoacidosis	0.000	0.975	0.025
E84 Cystic fibrosis	0.000	0.975	0.025
E77 Disorders of glycoprotein metabolism	0.000	0.975	0.025
E76 Disorders of glycosaminoglycan metabolism	0.000	0.975	0.025
E72 Other disorders of amino-acid metabolism	0.000	0.975	0.025
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.975	0.025
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.975	0.025
E11.8 With unspecified complications	0.000	0.976	0.024
E11.7 With multiple complications	0.000	0.976	0.024
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.976	0.024
E11.5 With peripheral circulatory complications	0.000	0.977	0.023
R31 Unspecified haematuria	0.023	0.977	0.000
E70 Disorders of aromatic amino-acid metabolism	0.000	0.977	0.023
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.977	0.023
E14.5 With peripheral circulatory complications	0.000	0.977	0.023
E88.9 Metabolic disorder, unspecified	0.000	0.977	0.023
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.978	0.022
E79 Disorders of purine and pyrimidine metabolism	0.000	0.978	0.022
E14.7 With multiple complications	0.000	0.978	0.022
E14.2 Withrenal complications	0.000	0.978	0.022
E14.0 With coma	0.000	0.978	0.022
E11.6 With other specified complications	0.000	0.978	0.022
E15 Nondiabetic hypoglycaemic coma	0.000	0.979	0.021
E46 Unspecified protein-energy malnutrition	0.000	0.979	0.021
E85.9 Amyloidosis, unspecified	0.000	0.979	0.021
E14.6 With other specified complications	0.000	0.979	0.021
E14.4 With neurological complications	0.000	0.980	0.020
E14.1 With ketoacidosis	0.000	0.980	0.020
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.980	0.020
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.980	0.020
E16.4 Abnormal secretion of gastrin	0.000	0.980	0.020
E16.3 Increased secretion of glucagon	0.000	0.980	0.020
E73 Lactose intolerance	0.000	0.981	0.019
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.981	0.019
E45 Retarded development following protein-energy malnutrition	0.000	0.981	0.019
E43 Unspecified severe protein-energy malnutrition	0.000	0.981	0.019
E42 Marasmic kwashiorkor	0.000	0.981	0.019
E41 Nutritional marasmus	0.000	0.981	0.019
E40 Kwashiorkor	0.000	0.981	0.019
E85.8 Other amyloidosis	0.000	0.981	0.019
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.981	0.019
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.981	0.019
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.981	0.019
E85.4 Organ-limited amyloidosis	0.000	0.982	0.018
E74 Other disorders of carbohydrate metabolism	0.000	0.982	0.018
E71.3 Disorders of fatty-acid metabolism	0.000	0.982	0.018
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.982	0.018
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.982	0.018
E71.0 Maple-syrup-urine disease	0.000	0.982	0.018
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.982	0.018
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.982	0.018
E72.5 Disorders of glycine metabolism	0.000	0.982	0.018
E72.4 Disorders of ornithine metabolism	0.000	0.982	0.018
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.982	0.018
E72.2 Disorders of urea cycle metabolism	0.000	0.982	0.018
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.982	0.018
E72.0 Disorders of amino-acid transport	0.000	0.982	0.018
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.982	0.018
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.982	0.018
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.982	0.018
E76.2 Other mucopolysaccharidoses	0.000	0.982	0.018
E76.1 Mucopolysaccharidosis, type II	0.000	0.982	0.018
E76.0 Mucopolysaccharidosis, type I	0.000	0.982	0.018
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.982	0.018
E77.8 Other disorders of glycoprotein metabolism	0.000	0.982	0.018
E77.1 Defects in glycoprotein degradation	0.000	0.982	0.018
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.982	0.018
E84.9 Cystic fibrosis, unspecified	0.000	0.982	0.018
E84.8 Cystic fibrosis with other manifestations	0.000	0.982	0.018
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.982	0.018
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.982	0.018
E85.3 Secondary systemic amyloidosis	0.000	0.982	0.018
E75.6 Lipid storage disorder, unspecified	0.000	0.982	0.017
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.982	0.017
E75.3 Sphingolipidosis, unspecified	0.000	0.982	0.017
E75.2 Other sphingolipidosis	0.000	0.982	0.017
E75.1 Other gangliosidosis	0.000	0.982	0.017
E75.0 GM2 gangliosidosis	0.000	0.982	0.017
E65-E68 Obesity and other hyperalimentation	0.000	0.982	0.018
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.983	0.017
K90-K93 Other diseases of the digestive system	0.000	0.983	0.017
M25.59 Pain in joint (Site unspecified)	0.000	0.983	0.017
E11.3 With ophthalmic complications	0.000	0.983	0.017
E75.5 Other lipid storage disorders	0.000	0.983	0.017
E80.4 Gilbert's syndrome	0.000	0.983	0.017
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.983	0.017
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.983	0.017
E70.2 Disorders of tyrosine metabolism	0.000	0.983	0.017
E70.1 Other hyperphenylalaninaemias	0.000	0.983	0.017
E70.0 Classical phenylketonuria	0.000	0.983	0.017
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.983	0.017
E80.5 Crigler-Najjar syndrome	0.000	0.983	0.017
E80.3 Defects of catalase and peroxydase	0.000	0.983	0.017
E80.1 Porphyria cutanea tarda	0.000	0.983	0.017
E80.0 Hereditary erythropoietic porphyria	0.000	0.983	0.017
E80.6 Other disorders of bilirubin metabolism	0.000	0.984	0.016
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.984	0.016
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.984	0.016
E79.1 Lesch-Nyhan syndrome	0.000	0.984	0.016
E14.8 With unspecified complications	0.000	0.984	0.016
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.984	0.016
E80.2 Other porphyria	0.000	0.984	0.015
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.985	0.015
E70.3 Albinism	0.000	0.985	0.015
E16.1 Other hypoglycaemia	0.000	0.986	0.014
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.986	0.014
E65 Localised adiposity	0.000	0.986	0.014
E73.8 Other lactose intolerance	0.000	0.986	0.014
E73.1 Secondary lactase deficiency	0.000	0.986	0.014
E73.0 Congenital lactase deficiency	0.000	0.986	0.014
G31.8 Other specified degenerative diseases of nervous system	0.000	0.986	0.014
E87.0 Hyperosmolality and hypernatraemia	0.000	0.986	0.014
E87.5 Hyperkalaemia	0.000	0.986	0.014
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.986	0.013
E44.1 Mild protein-energy malnutrition	0.000	0.986	0.013
E44.0 Moderate protein-energy malnutrition	0.000	0.986	0.013
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.986	0.014
E89.4 Postprocedural ovarian failure	0.000	0.987	0.013
E87.3 Alkalosis	0.000	0.987	0.013
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.987	0.013
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.987	0.013
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.987	0.013
E74.2 Disorders of galactose metabolism	0.000	0.987	0.013
E74.1 Disorders of fructose metabolism	0.000	0.987	0.013
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.987	0.013
E67 Other hyperalimentation	0.000	0.987	0.013
E68 Sequelae of hyperalimentation	0.000	0.987	0.013
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.987	0.013
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.987	0.013
E89.5 Postprocedural testicular hypofunction	0.000	0.987	0.013
E89.1 Postprocedural hypoinsulinaemia	0.000	0.987	0.013
E89.2 Postprocedural hypoparathyroidism	0.000	0.987	0.013
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.987	0.013
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.988	0.012
G31.0 Circumscribed brain atrophy	0.000	0.988	0.012
E74.0 Glycogen storage disease	0.000	0.988	0.012
G44.2 Tension-type headache	0.012	0.988	0.000
G30 Alzheimer's disease	0.000	0.988	0.012
E83.5 Disorders of calcium metabolism	0.000	0.988	0.012
E87.4 Mixed disorder of acid-base balance	0.000	0.989	0.011
G30-G32 Other degenerative diseases of the nervous system	0.000	0.989	0.011
E87.7 Fluid overload	0.000	0.989	0.011
E50-E64 Other nutritional deficiencies	0.000	0.989	0.011
E78.2 Mixed hyperlipidaemia	0.000	0.989	0.011
G30.9 Alzheimer's disease, unspecified	0.000	0.989	0.011
G30.0 Alzheimer's disease with early onset	0.000	0.989	0.011
E78.3 Hyperchylomicronaemia	0.000	0.989	0.010
E89.0 Postprocedural hypothyroidism	0.000	0.989	0.011
E78.1 Pure hyperglyceridaemia	0.000	0.990	0.010
M25.50 Pain in joint (Multiple sites)	0.000	0.990	0.010
E78.4 Other hyperlipidaemia	0.000	0.990	0.010
E78.6 Lipoprotein deficiency	0.000	0.990	0.010
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.990	0.010
E67.8 Other specified hyperalimentation	0.000	0.990	0.009
E67.3 Hypervitaminosis D	0.000	0.990	0.009
E67.2 Megavitamin-B6 syndrome	0.000	0.990	0.009
E67.1 Hypercarotenaemia	0.000	0.990	0.009
E67.0 Hypervitaminosis A	0.000	0.990	0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.991	0.009
K93.1 Megacolon in Chagas' disease	0.000	0.991	0.009
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.991	0.009
G30.8 Other Alzheimer's disease	0.000	0.991	0.009
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.991	0.009
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.991	0.008
G30.1 Alzheimer's disease with late onset	0.000	0.991	0.009
E73.9 Lactose intolerance, unspecified	0.001	0.991	0.008
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.992	0.008
E63 Other nutritional deficiencies	0.000	0.992	0.008
E50 Vitamin A deficiency	0.000	0.992	0.008
E60 Dietary zinc deficiency	0.000	0.992	0.008
E59 Dietary selenium deficiency	0.000	0.992	0.008
E54 Ascorbic acid deficiency	0.000	0.992	0.008
E52 Niacin deficiency [pellagra]	0.000	0.992	0.008
E58 Dietary calcium deficiency	0.000	0.992	0.008
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.992	0.008
E56 Other vitamin deficiencies	0.000	0.992	0.008
E87.2 Acidosis	0.000	0.992	0.008
E51 Thiamine deficiency	0.000	0.992	0.008
E00-E07 Disorders of thyroid gland	0.000	0.992	0.008
G31.2 Degeneration of nervous system due to alcohol	0.000	0.993	0.007
E53 Deficiency of other B group vitamins	0.000	0.993	0.007
E89.3 Postprocedural hypopituitarism	0.000	0.993	0.007
G44 Other headache syndromes	0.007	0.993	0.000
E55 Vitamin D deficiency	0.000	0.993	0.006
G44.8 Other specified headache syndromes	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.994	0.006
E50.9 Vitamin A deficiency, unspecified	0.000	0.994	0.006
E50.8 Other manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.994	0.006
E50.5 Vitamin A deficiency with night blindness	0.000	0.994	0.006
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.994	0.006
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.994	0.006
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.994	0.006
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.994	0.006
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.994	0.006
E63.9 Nutritional deficiency, unspecified	0.000	0.994	0.006
E63.8 Other specified nutritional deficiencies	0.000	0.994	0.006
E63.1 Imbalance of constituents of food intake	0.000	0.994	0.006
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.994	0.006
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.994	0.006
E64.8 Sequelae of other nutritional deficiencies	0.000	0.994	0.006
E64.3 Sequelae of rickets	0.000	0.994	0.006
E64.2 Sequelae of vitamin C deficiency	0.000	0.994	0.006
E64.1 Sequelae of vitamin A deficiency	0.000	0.994	0.006
E64.0 Sequelae of protein-energy malnutrition	0.000	0.994	0.006
Z34.9 Supervision of normal pregnancy, unspecified	0.006	0.994	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.994	0.006
E53.9 Vitamin B deficiency, unspecified	0.000	0.994	0.006
E56.9 Vitamin deficiency, unspecified	0.000	0.994	0.006
E56.8 Deficiency of other vitamins	0.000	0.994	0.006
E56.0 Deficiency of vitamin E	0.000	0.994	0.006
E51.9 Thiamine deficiency, unspecified	0.000	0.994	0.006
E51.8 Other manifestations of thiamine deficiency	0.000	0.994	0.006
E51.1 Beriberi	0.000	0.994	0.006
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.994	0.006
E20-E35 Disorders of other endocrine glands	0.000	0.994	0.006
G54.9 Nerve root and plexus disorder, unspecified	0.006	0.994	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.994	0.006
E00 Congenital iodine-deficiency syndrome	0.000	0.994	0.006
E56.1 Deficiency of vitamin K	0.000	0.994	0.005
E53.1 Pyridoxine deficiency	0.000	0.994	0.005
E53.0 Riboflavin deficiency	0.000	0.994	0.005
K22.8 Other specified diseases of oesophagus	0.006	0.994	0.000
E51.2 Wernicke's encephalopathy	0.000	0.995	0.005
E07 Other disorders of thyroid	0.000	0.995	0.005
G44.0 Cluster headache syndrome	0.005	0.995	0.000
E06 Thyroiditis	0.000	0.995	0.005
N60.1 Diffuse cystic mastopathy	0.000	0.995	0.005
G44.1 Vascular headache, not elsewhere classified	0.005	0.995	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.005	0.995	0.000
E86 Volume depletion	0.000	0.995	0.005
E14.9 Without complications	0.000	0.995	0.005
E55.0 Rickets, active	0.000	0.995	0.005
G44.3 Chronic posttraumatic headache	0.005	0.995	0.000
E78.8 Other disorders of lipoprotein metabolism	0.001	0.995	0.004
K56.4 Other impaction of intestine	0.005	0.995	0.000
E04 Other non-toxic goitre	0.000	0.995	0.005
E20 Hypoparathyroidism	0.000	0.995	0.005
E61 Deficiency of other nutrient elements	0.001	0.995	0.004
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.995	0.004
E26 Hyperaldosteronism	0.000	0.995	0.005
E27 Other disorders of adrenal gland	0.000	0.995	0.004
E29 Testicular dysfunction	0.000	0.995	0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.996	0.004
E32 Diseases of thymus	0.000	0.996	0.004
E31 Polyglandular dysfunction	0.000	0.996	0.004
E30 Disorders of puberty, not elsewhere classified	0.000	0.996	0.004
E25 Adrenogenital disorders	0.000	0.996	0.004
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.996	0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.996	0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.996	0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.996	0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.996	0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.996	0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.996	0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.996	0.004
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.004	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.004	0.996	0.000
M41.9 Scoliosis, unspecified	0.004	0.996	0.000
E24 Cushing's syndrome	0.000	0.996	0.004
E07.1 Dyshormogenetic goitre	0.000	0.996	0.004
E07.0 Hypersecretion of calcitonin	0.000	0.996	0.004
E53.8 Deficiency of other specified B group vitamins	0.000	0.996	0.004
E06.5 Other chronic thyroiditis	0.000	0.996	0.004
E06.4 Drug-induced thyroiditis	0.000	0.996	0.004
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.996	0.004
E06.1 Subacute thyroiditis	0.000	0.996	0.004
E06.0 Acute thyroiditis	0.000	0.996	0.004
E20.9 Hypoparathyroidism, unspecified	0.000	0.996	0.004
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.996	0.004
E04.9 Non-toxic goitre, unspecified	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.000	0.996	0.004
E34 Other endocrine disorders	0.000	0.996	0.004
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.996	0.004
E06.3 Autoimmune thyroiditis	0.000	0.996	0.004
E07.8 Other specified disorders of thyroid	0.000	0.996	0.004
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.000	0.996	0.004
E04.0 Non-toxic diffuse goitre	0.000	0.996	0.004
E24.2 Drug-induced Cushing's syndrome	0.000	0.996	0.004
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.996	0.004
M41.94 Scoliosis, unspecified (Thoracic region)	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.000	0.996	0.004
E04.8 Other specified non-toxic goitre	0.000	0.996	0.004
E20.8 Other hypoparathyroidism	0.000	0.996	0.004
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.004
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.004
E61.9 Deficiency of nutrient element, unspecified	0.001	0.996	0.003
E61.8 Deficiency of other specified nutrient elements	0.001	0.996	0.003
E61.7 Deficiency of multiple nutrient elements	0.001	0.996	0.003
E61.6 Vanadium deficiency	0.001	0.996	0.003
E61.5 Molybdenum deficiency	0.001	0.996	0.003
E61.4 Chromium deficiency	0.001	0.996	0.003
E61.3 Manganese deficiency	0.001	0.996	0.003
E61.0 Copper deficiency	0.001	0.996	0.003
G82.5 Tetraplegia, unspecified	0.000	0.996	0.004
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.996	0.004
M25.56 Pain in joint (Lower leg)	0.000	0.996	0.004
M41.96 Scoliosis, unspecified (Lumbar region)	0.004	0.996	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.996	0.003
E26.9 Hyperaldosteronism, unspecified	0.000	0.996	0.003
E26.8 Other hyperaldosteronism	0.000	0.996	0.003
E26.1 Secondary hyperaldosteronism	0.000	0.996	0.003
E29.1 Testicular hypofunction	0.000	0.996	0.004
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.004	0.996	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.000	0.996	0.003
E27.0 Other adrenocortical overactivity	0.000	0.996	0.003
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.003
E29.8 Other testicular dysfunction	0.000	0.996	0.003
E29.0 Testicular hyperfunction	0.000	0.996	0.003
K02.9 Dental caries, unspecified	0.000	0.996	0.004
G82.4 Spastic tetraplegia	0.000	0.996	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.003
E03 Other hypothyroidism	0.000	0.996	0.003
E28 Ovarian dysfunction	0.000	0.996	0.003
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.997	0.003
E25.8 Other adrenogenital disorders	0.000	0.997	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.003
E30.9 Disorder of puberty, unspecified	0.000	0.997	0.003
E30.8 Other disorders of puberty	0.000	0.997	0.003
E30.1 Precocious puberty	0.000	0.997	0.003
E30.0 Delayed puberty	0.000	0.997	0.003
E31.9 Polyglandular dysfunction, unspecified	0.000	0.997	0.003
E31.8 Other polyglandular dysfunction	0.000	0.997	0.003
E31.1 Polyglandular hyperfunction	0.000	0.997	0.003
E31.0 Autoimmune polyglandular failure	0.000	0.997	0.003
E32.9 Disease of thymus, unspecified	0.000	0.997	0.003
E32.8 Other diseases of thymus	0.000	0.997	0.003
E32.1 Abscess of thymus	0.000	0.997	0.003
E32.0 Persistent hyperplasia of thymus	0.000	0.997	0.003
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.997	0.003
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.003
K02.8 Other dental caries	0.000	0.997	0.003
C71.2 Temporal lobe	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.997	0.003
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.003	0.997	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.997	0.003
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.003
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.003
E24.1 Nelson's syndrome	0.000	0.997	0.003
G82 Paraplegia and tetraplegia	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.997	0.003
E61.2 Magnesium deficiency	0.001	0.997	0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.997	0.003
E87.6 Hypokalaemia	0.000	0.997	0.003
G71.1 Myotonic disorders	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.000	0.997	0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.997	0.003
E66 Obesity	0.000	0.997	0.003
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.000	0.997	0.003
E05.4 Thyrotoxicosis factitia	0.000	0.997	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.997	0.003
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.003
E03.8 Other specified hypothyroidism	0.000	0.997	0.003
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.997	0.003
E34.8 Other specified endocrine disorders	0.000	0.997	0.003
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.997	0.003
K02 Dental caries	0.000	0.997	0.003
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
E27.2 Addisonian crisis	0.000	0.997	0.003
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.997	0.003
M96.5 Postradiation scoliosis	0.000	0.997	0.003
M96.4 Postsurgical lordosis	0.000	0.997	0.003
M96.3 Postlaminectomy kyphosis	0.000	0.997	0.003
M96.2 Postradiation kyphosis	0.000	0.997	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.997	0.003
K91.1 Postgastric surgery syndromes	0.000	0.997	0.003
E03.5 Myxoedema coma	0.000	0.997	0.003
E03.4 Atrophy of thyroid (acquired)	0.000	0.997	0.003
E03.3 Postinfectious hypothyroidism	0.000	0.997	0.003
E03.1 Congenital hypothyroidism without goitre	0.000	0.997	0.003
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003
K51.2 Ulcerative (chronic) proctitis	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.003
E28.8 Other ovarian dysfunction	0.000	0.997	0.003
E28.1 Androgen excess	0.000	0.997	0.003
E28.0 Oestrogen excess	0.000	0.997	0.003
K22.0 Achalasia of cardia	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.000	0.997	0.003
K56.2 Volvulus	0.003	0.997	0.000
N04.9 Unspecified	0.000	0.997	0.003
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.002
G82.3 Flaccid tetraplegia	0.000	0.997	0.002
G82.0 Flaccid paraplegia	0.000	0.997	0.002
K02.1 Caries of dentin	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.997	0.002
T78.3 Angioneurotic oedema	0.000	0.997	0.003
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.002
G71 Primary disorders of muscles	0.000	0.997	0.002
E66.1 Drug-induced obesity	0.000	0.998	0.002
K62.5 Haemorrhage of anus and rectum	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations