TreeWAS – Variant ID: rs4361609

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.010	0.990
E10.1 With ketoacidosis	0.000	0.020	0.980
M45.X9 Ankylosing spondylitis (Site unspecified)	0.974	0.026	0.000
E10.4 With neurological complications	0.000	0.124	0.876
E10.2 With renal complications	0.000	0.215	0.785
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.782	0.218	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.773	0.227	0.000
E10.8 With unspecified complications	0.000	0.238	0.762
M45 Ankylosing spondylitis	0.761	0.239	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.749	0.251	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.743	0.257	0.000
C83.3 Large cell (diffuse)	0.739	0.261	0.000
E10.5 With peripheral circulatory complications	0.000	0.267	0.733
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.723	0.277	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.718	0.282	0.000
E10.7 With multiple complications	0.000	0.283	0.717
E10.0 With coma	0.000	0.283	0.717
E10.6 With other specified complications	0.000	0.302	0.698
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.697	0.303	0.000
C81 Hodgkin's disease	0.652	0.348	0.000
C82.0 Small cleaved cell, follicular	0.644	0.356	0.000
E10-E14 Diabetes mellitus	0.000	0.365	0.635
C82.3 Follicular lymphoma grade IIIa	0.629	0.371	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.621	0.379	0.000
C81.9 Hodgkin's disease, unspecified	0.592	0.408	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.581	0.419	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.580	0.420	0.000
C83.1 Small cleaved cell (diffuse)	0.570	0.430	0.000
C82.6 Cutaneous follicle centre lymphoma	0.554	0.446	0.000
C82.5 Diffuse follicle centre lymphoma	0.554	0.446	0.000
C82.4 Follicular lymphoma grade IIIb	0.554	0.446	0.000
C82.2 Large cell, follicular	0.554	0.446	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.548	0.452	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.546	0.454	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.546	0.454	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.546	0.454	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.546	0.454	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.546	0.454	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.546	0.454	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.546	0.454	0.000
C88 Malignant immunoproliferative diseases	0.542	0.458	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.537	0.463	0.000
C95 Leukaemia of unspecified cell type	0.537	0.463	0.000
C94 Other leukaemias of specified cell type	0.537	0.463	0.000
C93 Monocytic leukaemia	0.537	0.463	0.000
C86 Other specified types of T/NK-cell lymphoma	0.537	0.463	0.000
C83.7 Burkitt's tumour	0.533	0.467	0.000
C83.6 Undifferentiated (diffuse)	0.533	0.467	0.000
C83.5 Lymphoblastic (diffuse)	0.533	0.467	0.000
C83.4 Immunoblastic (diffuse)	0.533	0.467	0.000
C83.2 Mixed small and large cell (diffuse)	0.533	0.467	0.000
C85.1 B-cell lymphoma, unspecified	0.526	0.474	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.481	0.519
E14 Unspecified diabetes mellitus	0.000	0.484	0.516
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.485	0.515
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.515	0.485	0.000
C85.0 Lymphosarcoma	0.515	0.485	0.000
E27 Other disorders of adrenal gland	0.000	0.487	0.513
C85.7 Other specified types of non-Hodgkin's lymphoma	0.507	0.493	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.499	0.501
M45.X2 Ankylosing spondylitis (Cervical region)	0.500	0.499	0.000
E29 Testicular dysfunction	0.000	0.517	0.483
K90 Intestinal malabsorption	0.000	0.525	0.475
C81.7 Other Hodgkin's disease	0.468	0.532	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.468	0.532	0.000
C81.3 Lymphocytic depletion	0.468	0.532	0.000
C81.2 Mixed cellularity	0.468	0.532	0.000
C81.0 Lymphocytic predominance	0.468	0.532	0.000
E29.1 Testicular hypofunction	0.000	0.542	0.457
E12 Malnutrition-related diabetes mellitus	0.000	0.545	0.455
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.549	0.451
C92 Myeloid leukaemia	0.443	0.557	0.000
C81.1 Nodular sclerosis	0.442	0.557	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.562	0.438
E14.9 Without complications	0.000	0.569	0.431
E13 Other specified diabetes mellitus	0.000	0.570	0.430
E50-E64 Other nutritional deficiencies	0.000	0.572	0.428
E34 Other endocrine disorders	0.000	0.582	0.418
E22 Hyperfunction of pituitary gland	0.000	0.582	0.418
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.590	0.410
E27.8 Other specified disorders of adrenal gland	0.000	0.593	0.407
C84 Peripheral and cutaneous T-cell lymphomas	0.397	0.602	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.396	0.604	0.000
E20 Hypoparathyroidism	0.000	0.604	0.396
E27.2 Addisonian crisis	0.000	0.605	0.395
C88.9 Malignant immunoproliferative disease, unspecified	0.389	0.611	0.000
C88.7 Other malignant immunoproliferative diseases	0.389	0.611	0.000
C88.3 Immunoproliferative small intestinal disease	0.389	0.611	0.000
C88.2 Gamma heavy chain disease	0.389	0.611	0.000
C88.1 Alpha heavy chain disease	0.389	0.611	0.000
E14.3 With ophthalmic complications	0.000	0.613	0.387
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.386	0.614	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.385	0.615	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.385	0.615	0.000
C86.4 Blastic NK-cell lymphoma	0.385	0.615	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.385	0.615	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.385	0.615	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.385	0.615	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.385	0.615	0.000
C93.9 Monocytic leukaemia, unspecified	0.385	0.615	0.000
C93.7 Other monocytic leukaemia	0.385	0.615	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.385	0.615	0.000
C93.2 Subacute monocytic leukaemia	0.385	0.615	0.000
C93.1 Chronic monocytic leukaemia	0.385	0.615	0.000
C93.0 Acute monocytic leukaemia	0.385	0.615	0.000
C94.7 Other specified leukaemias	0.385	0.615	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.385	0.615	0.000
C94.5 Acute myelofibrosis	0.385	0.615	0.000
C94.4 Acute panmyelosis	0.385	0.615	0.000
C94.3 Mast cell leukaemia	0.385	0.615	0.000
C94.2 Acute megakaryoblastic leukaemia	0.385	0.615	0.000
C94.1 Chronic erythraemia	0.385	0.615	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.385	0.615	0.000
C95.9 Leukaemia, unspecified	0.385	0.615	0.000
C95.7 Other leukaemia of unspecified cell type	0.385	0.615	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.385	0.615	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.385	0.615	0.000
C95.0 Acute leukaemia of unspecified cell type	0.385	0.615	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.385	0.615	0.000
C96.8 Histiocytic sarcoma	0.385	0.615	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.385	0.615	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.385	0.615	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.385	0.615	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.385	0.615	0.000
C96.3 True histiocytic lymphoma	0.385	0.615	0.000
C96.2 Malignant mast cell tumour	0.385	0.615	0.000
C96.1 Malignant histiocytosis	0.385	0.615	0.000
C96.0 Letterer-Siwe disease	0.385	0.615	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.628	0.372
E32 Diseases of thymus	0.000	0.628	0.372
E31 Polyglandular dysfunction	0.000	0.628	0.372
E30 Disorders of puberty, not elsewhere classified	0.000	0.628	0.372
E25 Adrenogenital disorders	0.000	0.628	0.372
E14.7 With multiple complications	0.000	0.630	0.370
E14.6 With other specified complications	0.000	0.630	0.370
E14.5 With peripheral circulatory complications	0.000	0.630	0.370
E14.4 With neurological complications	0.000	0.630	0.370
E14.2 Withrenal complications	0.000	0.630	0.370
E14.1 With ketoacidosis	0.000	0.630	0.370
E14.0 With coma	0.000	0.630	0.370
E55 Vitamin D deficiency	0.000	0.631	0.369
E27.5 Adrenomedullary hyperfunction	0.000	0.632	0.368
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.632	0.368
E27.0 Other adrenocortical overactivity	0.000	0.632	0.368
C91 Lymphoid leukaemia	0.367	0.632	0.000
E24 Cushing's syndrome	0.000	0.633	0.367
E14.8 With unspecified complications	0.000	0.647	0.353
E29.9 Testicular dysfunction, unspecified	0.000	0.654	0.346
E29.8 Other testicular dysfunction	0.000	0.654	0.346
E29.0 Testicular hyperfunction	0.000	0.654	0.346
E34.9 Endocrine disorder, unspecified	0.000	0.655	0.344
E23.0 Hypopituitarism	0.000	0.656	0.344
E23.2 Diabetes insipidus	0.000	0.658	0.342
K90.3 Pancreatic steatorrhoea	0.000	0.659	0.341
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.659	0.341
K90.1 Tropical sprue	0.000	0.659	0.341
E53 Deficiency of other B group vitamins	0.000	0.660	0.340
E16 Other disorders of pancreatic internal secretion	0.000	0.665	0.335
E28 Ovarian dysfunction	0.000	0.665	0.335
E23.7 Disorder of pituitary gland, unspecified	0.000	0.668	0.332
K90.9 Intestinal malabsorption, unspecified	0.000	0.670	0.330
E22.0 Acromegaly and pituitary gigantism	0.000	0.671	0.329
E55.9 Vitamin D deficiency, unspecified	0.000	0.673	0.327
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.673	0.327
E12.9 Without complications	0.000	0.673	0.326
E12.8 With unspecified complications	0.000	0.673	0.326
E12.7 With multiple complications	0.000	0.673	0.326
E12.6 With other specified complications	0.000	0.673	0.326
E12.5 With peripheral circulatory complications	0.000	0.673	0.326
E12.4 With neurological complications	0.000	0.673	0.326
E12.3 With ophthalmic complications	0.000	0.673	0.326
E12.2 With renal complications	0.000	0.673	0.326
E12.1 With ketoacidosis	0.000	0.673	0.326
E12.0 With coma	0.000	0.673	0.326
K90.8 Other intestinal malabsorption	0.000	0.675	0.325
E23.6 Other disorders of pituitary gland	0.000	0.677	0.323
C83.0 Small cell (diffuse)	0.321	0.679	0.001
C92.9 Myeloid leukaemia, unspecified	0.318	0.682	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.318	0.682	0.000
C92.7 Other myeloid leukaemia	0.318	0.682	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.318	0.682	0.000
C92.5 Acute myelomonocytic leukaemia	0.318	0.682	0.000
C92.4 Acute promyelocytic leukaemia	0.318	0.682	0.000
C92.3 Myeloid sarcoma	0.318	0.682	0.000
C92.2 Subacute myeloid leukaemia	0.318	0.682	0.000
E40-E46 Malnutrition	0.000	0.683	0.317
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.686	0.314
E23.1 Drug-induced hypopituitarism	0.000	0.686	0.314
E13.8 With unspecified complications	0.000	0.691	0.308
E13.7 With multiple complications	0.000	0.691	0.308
E13.6 With other specified complications	0.000	0.691	0.308
E13.5 With peripheral circulatory complications	0.000	0.691	0.308
E13.4 With neurological complications	0.000	0.691	0.308
E13.3 With ophthalmic complications	0.000	0.691	0.308
E13.2 With renal complications	0.000	0.691	0.308
E13.1 With ketoacidosis	0.000	0.691	0.308
E13.0 With coma	0.000	0.691	0.308
E20.9 Hypoparathyroidism, unspecified	0.000	0.692	0.307
C92.1 Chronic myeloid leukaemia	0.307	0.693	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.693	0.307
E63 Other nutritional deficiencies	0.000	0.693	0.307
E56 Other vitamin deficiencies	0.000	0.693	0.307
E51 Thiamine deficiency	0.000	0.693	0.307
E50 Vitamin A deficiency	0.000	0.693	0.307
E60 Dietary zinc deficiency	0.000	0.693	0.307
E59 Dietary selenium deficiency	0.000	0.693	0.307
E58 Dietary calcium deficiency	0.000	0.693	0.307
E54 Ascorbic acid deficiency	0.000	0.693	0.307
E52 Niacin deficiency [pellagra]	0.000	0.693	0.307
E34.8 Other specified endocrine disorders	0.000	0.697	0.303
E34.5 Androgen resistance syndrome	0.000	0.700	0.300
E34.4 Constitutional tall stature	0.000	0.700	0.300
E34.3 Short stature, not elsewhere classified	0.000	0.700	0.300
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.700	0.300
E34.1 Other hypersecretion of intestinal hormones	0.000	0.700	0.300
E34.0 Carcinoid syndrome	0.000	0.700	0.300
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.700	0.299
E22.8 Other hyperfunction of pituitary gland	0.000	0.700	0.299
E15 Nondiabetic hypoglycaemic coma	0.000	0.706	0.294
E53.8 Deficiency of other specified B group vitamins	0.000	0.707	0.292
E22.1 Hyperprolactinaemia	0.000	0.708	0.292
E26 Hyperaldosteronism	0.000	0.708	0.292
C91.5 Adult T-cell leukaemia	0.290	0.710	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.711	0.289
J32.9 Chronic sinusitis, unspecified	0.288	0.712	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.285	0.715	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.285	0.715	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.285	0.715	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.285	0.715	0.000
C84.3 Lymphoepithelioid lymphoma	0.285	0.715	0.000
C84.2 T-zone lymphoma	0.285	0.715	0.000
C84.1 Sezary's diease	0.285	0.715	0.000
C84.0 Mycosis fungoides	0.285	0.715	0.000
C91.9 Lymphoid leukaemia, unspecified	0.284	0.716	0.000
E20.8 Other hypoparathyroidism	0.000	0.716	0.284
E20.1 Pseudohypoparathyroidism	0.000	0.716	0.284
E20.0 Idiopathic hypoparathyroidism	0.000	0.716	0.284
E13.9 Without complications	0.000	0.717	0.283
E16.2 Hypoglycaemia, unspecified	0.000	0.720	0.280
E27.9 Disorder of adrenal gland, unspecified	0.000	0.720	0.279
C91.0 Acute lymphoblastic leukaemia	0.272	0.728	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.733	0.267
E25.8 Other adrenogenital disorders	0.000	0.733	0.267
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.733	0.267
E30.9 Disorder of puberty, unspecified	0.000	0.733	0.267
E30.8 Other disorders of puberty	0.000	0.733	0.267
E30.1 Precocious puberty	0.000	0.733	0.267
E30.0 Delayed puberty	0.000	0.733	0.267
E31.9 Polyglandular dysfunction, unspecified	0.000	0.733	0.267
E31.8 Other polyglandular dysfunction	0.000	0.733	0.267
E31.1 Polyglandular hyperfunction	0.000	0.733	0.267
E31.0 Autoimmune polyglandular failure	0.000	0.733	0.267
E32.9 Disease of thymus, unspecified	0.000	0.733	0.267
E32.8 Other diseases of thymus	0.000	0.733	0.267
E32.1 Abscess of thymus	0.000	0.733	0.267
E32.0 Persistent hyperplasia of thymus	0.000	0.733	0.267
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.733	0.267
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.733	0.267
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.733	0.267
E55.0 Rickets, active	0.000	0.735	0.265
C91.8 Mature B-cell leukaemia Burkitt-type	0.263	0.736	0.000
C91.7 Other lymphoid leukaemia	0.263	0.736	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.263	0.736	0.000
C91.3 Prolymphocytic leukaemia	0.263	0.736	0.000
C91.2 Subacute lymphocytic leukaemia	0.263	0.736	0.000
E24.8 Other Cushing's syndrome	0.000	0.736	0.263
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.736	0.263
E24.3 Ectopic ACTH syndrome	0.000	0.736	0.263
E24.2 Drug-induced Cushing's syndrome	0.000	0.736	0.263
E24.1 Nelson's syndrome	0.000	0.736	0.263
E24.0 Pituitary-dependent Cushing's disease	0.000	0.736	0.263
E24.9 Cushing's syndrome, unspecified	0.000	0.741	0.259
E28.3 Primary ovarian failure	0.000	0.743	0.257
C90 Multiple myeloma and malignant plasma cell neoplasms	0.253	0.746	0.001
E61 Deficiency of other nutrient elements	0.000	0.749	0.251
K90-K93 Other diseases of the digestive system	0.000	0.751	0.249
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.753	0.247
E53.1 Pyridoxine deficiency	0.000	0.756	0.244
E53.0 Riboflavin deficiency	0.000	0.756	0.244
C92.0 Acute myeloid leukaemia	0.241	0.759	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.759	0.240
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.759	0.240
E16.4 Abnormal secretion of gastrin	0.000	0.759	0.240
E16.3 Increased secretion of glucagon	0.000	0.759	0.240
E28.9 Ovarian dysfunction, unspecified	0.000	0.760	0.240
E28.8 Other ovarian dysfunction	0.000	0.760	0.240
E28.1 Androgen excess	0.000	0.760	0.240
E28.0 Oestrogen excess	0.000	0.760	0.240
C84.4 Peripheral T-cell lymphoma	0.239	0.760	0.001
E16.1 Other hypoglycaemia	0.000	0.765	0.235
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.770	0.230
K91.3 Postoperative intestinal obstruction	0.000	0.770	0.230
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.772	0.228
E45 Retarded development following protein-energy malnutrition	0.000	0.772	0.228
E43 Unspecified severe protein-energy malnutrition	0.000	0.772	0.228
E42 Marasmic kwashiorkor	0.000	0.772	0.228
E41 Nutritional marasmus	0.000	0.772	0.228
E40 Kwashiorkor	0.000	0.772	0.228
E50.9 Vitamin A deficiency, unspecified	0.000	0.780	0.220
E50.8 Other manifestations of vitamin A deficiency	0.000	0.780	0.220
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.780	0.220
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.780	0.220
E50.5 Vitamin A deficiency with night blindness	0.000	0.780	0.220
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.780	0.220
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.780	0.220
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.780	0.220
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.780	0.220
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.780	0.220
E51.9 Thiamine deficiency, unspecified	0.000	0.780	0.220
E51.8 Other manifestations of thiamine deficiency	0.000	0.780	0.220
E51.2 Wernicke's encephalopathy	0.000	0.780	0.220
E51.1 Beriberi	0.000	0.780	0.220
E56.9 Vitamin deficiency, unspecified	0.000	0.780	0.220
E56.8 Deficiency of other vitamins	0.000	0.780	0.220
E56.1 Deficiency of vitamin K	0.000	0.780	0.220
E56.0 Deficiency of vitamin E	0.000	0.780	0.220
E63.9 Nutritional deficiency, unspecified	0.000	0.780	0.220
E63.8 Other specified nutritional deficiencies	0.000	0.780	0.220
E63.1 Imbalance of constituents of food intake	0.000	0.780	0.220
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.780	0.220
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.780	0.220
E64.8 Sequelae of other nutritional deficiencies	0.000	0.780	0.220
E64.3 Sequelae of rickets	0.000	0.780	0.220
E64.2 Sequelae of vitamin C deficiency	0.000	0.780	0.220
E64.1 Sequelae of vitamin A deficiency	0.000	0.780	0.220
E64.0 Sequelae of protein-energy malnutrition	0.000	0.780	0.220
C84.5 Other and unspecified T-cell lymphomas	0.218	0.782	0.001
E53.9 Vitamin B deficiency, unspecified	0.000	0.789	0.211
E26.8 Other hyperaldosteronism	0.000	0.791	0.209
E26.1 Secondary hyperaldosteronism	0.000	0.791	0.209
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.795	0.205
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.805	0.195
C91.4 Hairy-cell leukaemia	0.195	0.805	0.001
E26.0 Primary hyperaldosteronism	0.000	0.805	0.195
C90.3 Solitary plasmacytoma	0.181	0.818	0.001
C90.1 Plasma cell leukaemia	0.181	0.818	0.001
E61.9 Deficiency of nutrient element, unspecified	0.000	0.820	0.180
E61.8 Deficiency of other specified nutrient elements	0.000	0.820	0.180
E61.7 Deficiency of multiple nutrient elements	0.000	0.820	0.180
E61.6 Vanadium deficiency	0.000	0.820	0.180
E61.5 Molybdenum deficiency	0.000	0.820	0.180
E61.4 Chromium deficiency	0.000	0.820	0.180
E61.3 Manganese deficiency	0.000	0.820	0.180
E61.0 Copper deficiency	0.000	0.820	0.180
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.821	0.179
E46 Unspecified protein-energy malnutrition	0.000	0.824	0.175
E28.2 Polycystic ovarian syndrome	0.000	0.826	0.174
E65-E68 Obesity and other hyperalimentation	0.000	0.831	0.169
K91.5 Postcholecystectomy syndrome	0.000	0.835	0.165
E44.1 Mild protein-energy malnutrition	0.000	0.836	0.163
E44.0 Moderate protein-energy malnutrition	0.000	0.836	0.163
E00-E07 Disorders of thyroid gland	0.000	0.838	0.161
E61.2 Magnesium deficiency	0.000	0.841	0.159
K91.1 Postgastric surgery syndromes	0.000	0.843	0.156
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.844	0.155
E26.9 Hyperaldosteronism, unspecified	0.001	0.847	0.153
E61.1 Iron deficiency	0.000	0.847	0.153
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.853	0.147
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.853	0.147
E21.4 Other specified disorders of parathyroid gland	0.000	0.853	0.147
E21.2 Other hyperparathyroidism	0.000	0.853	0.147
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.861	0.139
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.864	0.136
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.864	0.136
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.871	0.128
K93.1 Megacolon in Chagas' disease	0.000	0.871	0.128
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.871	0.128
C90.2 Plasmacytoma, extramedullary	0.127	0.872	0.001
E67 Other hyperalimentation	0.000	0.879	0.121
E68 Sequelae of hyperalimentation	0.000	0.879	0.121
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.884	0.116
E00 Congenital iodine-deficiency syndrome	0.000	0.884	0.116
E21.3 Hyperparathyroidism, unspecified	0.000	0.886	0.114
E11 Non-insulin-dependent diabetes mellitus	0.000	0.887	0.113
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.895	0.104
E05.5 Thyroid crisis or storm	0.000	0.900	0.100
E05.4 Thyrotoxicosis factitia	0.000	0.900	0.100
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.900	0.100
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.900	0.100
E06 Thyroiditis	0.000	0.902	0.098
E07 Other disorders of thyroid	0.000	0.903	0.097
E11.1 With ketoacidosis	0.000	0.904	0.096
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.905	0.095
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.906	0.094
D86.9 Sarcoidosis, unspecified	0.000	0.906	0.094
D86 Sarcoidosis	0.000	0.909	0.091
E67.8 Other specified hyperalimentation	0.000	0.913	0.087
E67.3 Hypervitaminosis D	0.000	0.913	0.087
E67.2 Megavitamin-B6 syndrome	0.000	0.913	0.087
E67.1 Hypercarotenaemia	0.000	0.913	0.087
E67.0 Hypervitaminosis A	0.000	0.913	0.087
E05.8 Other thyrotoxicosis	0.000	0.915	0.085
E03 Other hypothyroidism	0.000	0.916	0.084
E21.0 Primary hyperparathyroidism	0.000	0.916	0.083
E11.5 With peripheral circulatory complications	0.000	0.916	0.084
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.916	0.084
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.917	0.083
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.917	0.083
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.917	0.083
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.917	0.083
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.917	0.083
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.917	0.083
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.917	0.083
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.917	0.083
D86.0 Sarcoidosis of lung	0.000	0.918	0.082
E11.8 With unspecified complications	0.000	0.918	0.082
E11.7 With multiple complications	0.000	0.919	0.081
E65 Localised adiposity	0.001	0.920	0.079
D51 Vitamin B12 deficiency anaemia	0.000	0.921	0.079
D86.8 Sarcoidosis of other and combined sites	0.000	0.922	0.078
E11.3 With ophthalmic complications	0.000	0.922	0.078
E07.8 Other specified disorders of thyroid	0.000	0.923	0.077
D80-D89 Certain disorders involving the immune mechanism	0.000	0.923	0.077
E11.4 With neurological complications	0.000	0.924	0.076
E70-E90 Metabolic disorders	0.000	0.924	0.076
D50-D53 Nutritional anaemias	0.000	0.928	0.072
E06.5 Other chronic thyroiditis	0.000	0.929	0.070
E06.4 Drug-induced thyroiditis	0.000	0.929	0.070
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.929	0.070
E06.1 Subacute thyroiditis	0.000	0.929	0.070
E06.0 Acute thyroiditis	0.000	0.929	0.070
E07.1 Dyshormogenetic goitre	0.000	0.930	0.070
E07.0 Hypersecretion of calcitonin	0.000	0.930	0.070
C91.1 Chronic lymphocytic leukaemia	0.067	0.932	0.001
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.932	0.068
D80 Immunodeficiency with predominantly antibody defects	0.000	0.932	0.067
R31 Unspecified haematuria	0.067	0.933	0.000
D86.3 Sarcoidosis of skin	0.000	0.934	0.066
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.934	0.066
D86.1 Sarcoidosis of lymph nodes	0.000	0.934	0.066
E11.6 With other specified complications	0.000	0.934	0.066
E06.3 Autoimmune thyroiditis	0.000	0.935	0.065
E03.8 Other specified hypothyroidism	0.000	0.936	0.064
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.936	0.064
D50 Iron deficiency anaemia	0.000	0.936	0.064
K91.4 Colostomy and enterostomy malfunction	0.000	0.936	0.064
E73 Lactose intolerance	0.000	0.938	0.062
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.938	0.062
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.938	0.062
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.939	0.061
E03.5 Myxoedema coma	0.000	0.939	0.061
E03.4 Atrophy of thyroid (acquired)	0.000	0.939	0.061
E03.3 Postinfectious hypothyroidism	0.000	0.939	0.061
E03.1 Congenital hypothyroidism without goitre	0.000	0.939	0.061
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.939	0.061
E88 Other metabolic disorders	0.000	0.939	0.061
E06.9 Thyroiditis, unspecified	0.000	0.940	0.060
E85 Amyloidosis	0.000	0.940	0.060
D50.8 Other iron deficiency anaemias	0.000	0.941	0.059
K92 Other diseases of digestive system	0.000	0.942	0.058
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.942	0.058
D50.9 Iron deficiency anaemia, unspecified	0.000	0.943	0.057
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.943	0.057
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.943	0.057
D51.2 Transcobalamin II deficiency	0.000	0.943	0.057
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.943	0.057
J32 Chronic sinusitis	0.055	0.944	0.000
D83 Common variable immunodeficiency	0.000	0.945	0.055
D82 Immunodeficiency associated with other major defects	0.000	0.945	0.055
D81 Combined immunodeficiencies	0.000	0.945	0.055
E87.5 Hyperkalaemia	0.000	0.945	0.055
E84 Cystic fibrosis	0.000	0.945	0.055
E79 Disorders of purine and pyrimidine metabolism	0.000	0.945	0.055
E77 Disorders of glycoprotein metabolism	0.000	0.945	0.055
E76 Disorders of glycosaminoglycan metabolism	0.000	0.945	0.055
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.945	0.055
E72 Other disorders of amino-acid metabolism	0.000	0.945	0.055
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.945	0.055
E70 Disorders of aromatic amino-acid metabolism	0.000	0.945	0.055
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.945	0.055
K70-K77 Diseases of liver	0.000	0.945	0.055
E11.0 With coma	0.000	0.947	0.052
D84 Other immunodeficiencies	0.000	0.948	0.052
K73 Chronic hepatitis, not elsewhere classified	0.000	0.948	0.052
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.948	0.052
E87.7 Fluid overload	0.000	0.948	0.052
K75 Other inflammatory liver diseases	0.000	0.948	0.052
E73.9 Lactose intolerance, unspecified	0.000	0.948	0.052
C90.0 Multiple myeloma	0.050	0.948	0.001
K75.4 Autoimmune hepatitis	0.000	0.949	0.051
D53 Other nutritional anaemias	0.000	0.949	0.051
E74 Other disorders of carbohydrate metabolism	0.000	0.949	0.051
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.949	0.051
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.951	0.048
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.951	0.048
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.951	0.048
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.951	0.048
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.951	0.048
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.951	0.048
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.951	0.048
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.951	0.048
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.951	0.048
K73.9 Chronic hepatitis, unspecified	0.000	0.951	0.049
E87.0 Hyperosmolality and hypernatraemia	0.000	0.951	0.048
K72 Hepatic failure, not elsewhere classified	0.000	0.952	0.048
M45-M49 Spondylopathies	0.048	0.952	0.000
E85.4 Organ-limited amyloidosis	0.000	0.952	0.047

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations