TreeWAS – Variant ID: rs4376189

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.991	0.009
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.992	0.008
D68.2 Hereditary deficiency of other clotting factors	0.000	0.993	0.007
N94.1 Dyspareunia	0.007	0.993	0.000
Z57.2 Occupational exposure to dust	0.000	0.993	0.006
D69 Purpura and other haemorrhagic conditions	0.000	0.994	0.006
D68 Other coagulation defects	0.000	0.994	0.006
D69.6 Thrombocytopenia, unspecified	0.000	0.995	0.005
Z95.1 Presence of aortocoronary bypass graft	0.000	0.995	0.005
Z57 Occupational exposure to risk-factors	0.000	0.995	0.005
D68.6 Other Thrombophilia	0.000	0.995	0.005
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.995	0.005
D69.4 Other primary thrombocytopenia	0.000	0.995	0.005
D69.9 Haemorrhagic condition, unspecified	0.000	0.995	0.005
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.995	0.005
J45.9 Asthma, unspecified	0.000	0.995	0.005
Z57.3 Occupational exposure to other air contaminants	0.000	0.995	0.005
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.995	0.005
J31.0 Chronic rhinitis	0.000	0.995	0.005
D69.1 Qualitative platelet defects	0.000	0.995	0.004
N08.5 Glomerular disorders in systemic connective tissue disorders	0.000	0.996	0.004
R59.0 Localised enlarged lymph nodes	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
E24 Cushing's syndrome	0.000	0.996	0.004
E20-E35 Disorders of other endocrine glands	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
D69.8 Other specified haemorrhagic conditions	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.000	0.996	0.004
D68.0 Von Willebrand's disease	0.000	0.996	0.004
D68.4 Acquired coagulation factor deficiency	0.000	0.996	0.004
Z57.8 Occupational exposure to other risk-factors	0.000	0.996	0.004
D68.5 Primary Thrombophilia	0.000	0.996	0.004
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.000	0.996	0.004
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.996	0.004
D69.2 Other nonthrombocytopenic purpura	0.000	0.996	0.004
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.996	0.004
Z57.7 Occupational exposure to vibration	0.000	0.996	0.004
Z57.6 Occupational exposure to extreme temperature	0.000	0.996	0.004
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.996	0.004
Z57.1 Occupational exposure to radiation	0.000	0.996	0.004
Z57.0 Occupational exposure to noise	0.000	0.996	0.004
D69.5 Secondary thrombocytopenia	0.000	0.996	0.004
E23.2 Diabetes insipidus	0.000	0.996	0.004
E22.1 Hyperprolactinaemia	0.000	0.996	0.004
E24.9 Cushing's syndrome, unspecified	0.000	0.996	0.004
D68.1 Hereditary factor XI deficiency	0.000	0.996	0.004
E23.7 Disorder of pituitary gland, unspecified	0.000	0.996	0.004
U80.1 Methicillin resistant agent	0.000	0.996	0.004
D69.0 Allergic purpura	0.000	0.996	0.004
E29 Testicular dysfunction	0.000	0.996	0.004
E34 Other endocrine disorders	0.000	0.996	0.004
E27 Other disorders of adrenal gland	0.000	0.996	0.004
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.000	0.996	0.004
E24.0 Pituitary-dependent Cushing's disease	0.000	0.996	0.004
E28 Ovarian dysfunction	0.000	0.996	0.004
Y43.3 Other antineoplastic drugs	0.000	0.996	0.004
E28.3 Primary ovarian failure	0.000	0.996	0.004
E29.1 Testicular hypofunction	0.000	0.996	0.004
E26 Hyperaldosteronism	0.000	0.996	0.004
N08.8 Glomerular disorders in other diseases classified elsewhere	0.000	0.996	0.003
N08.1 Glomerular disorders in neoplastic diseases	0.000	0.996	0.003
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
E24.2 Drug-induced Cushing's syndrome	0.000	0.996	0.003
D67 Hereditary factor IX deficiency	0.000	0.996	0.003
Z63 Other problems related to primary support group, including family circumstances	0.000	0.996	0.004
R59.1 Generalised enlarged lymph nodes	0.004	0.996	0.000
R59 Enlarged lymph nodes	0.004	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
N02.9 Unspecified	0.000	0.997	0.003
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.000	0.997	0.003
E23.0 Hypopituitarism	0.000	0.997	0.003
Z59 Problems related to housing and economic circumstances	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.003
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.003
E24.1 Nelson's syndrome	0.000	0.997	0.003
E34.8 Other specified endocrine disorders	0.000	0.997	0.003
Z63.8 Other specified problems related to primary support group	0.000	0.997	0.003
Z63.7 Other stressful life events affecting family and household	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
R59.9 Enlarged lymph nodes, unspecified	0.003	0.997	0.000
E25 Adrenogenital disorders	0.000	0.997	0.003
N02 Recurrent and persistent haematuria	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.003
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.003
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.997	0.003
N00-N08 Glomerular diseases	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.000	0.997	0.003
R10.2 Pelvic and perineal pain	0.003	0.997	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.003	0.997	0.000
Z63.0 Problems in relationship with spouse or partner	0.000	0.997	0.003
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
E29.9 Testicular dysfunction, unspecified	0.000	0.997	0.003
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
E29.8 Other testicular dysfunction	0.000	0.997	0.003
E29.0 Testicular hyperfunction	0.000	0.997	0.003
M81.98 Osteoporosis, unspecified (Other)	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.003
E27.0 Other adrenocortical overactivity	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.003
N02.0 Minor glomerular abnormality	0.000	0.997	0.003
E20 Hypoparathyroidism	0.000	0.997	0.003
E27.2 Addisonian crisis	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.003
E28.8 Other ovarian dysfunction	0.000	0.997	0.003
E28.1 Androgen excess	0.000	0.997	0.003
E28.0 Oestrogen excess	0.000	0.997	0.003
J92.0 Pleural plaque with presence of asbestos	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
D66 Hereditary factor VIII deficiency	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.000	0.997	0.003
E26.1 Secondary hyperaldosteronism	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
N04 Nephrotic syndrome	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
O80.9 Single spontaneous delivery, unspecified	0.003	0.997	0.000
Z63.9 Problem related to primary support group, unspecified	0.000	0.997	0.003
Z63.3 Absence of family member	0.000	0.997	0.003
Z63.2 Inadequate family support	0.000	0.997	0.003
Z63.1 Problems in relationship with parents and in-laws	0.000	0.997	0.003
H92.0 Otalgia	0.000	0.997	0.003
R10.1 Pain localised to upper abdomen	0.003	0.997	0.000
Z59.0 Homelessness	0.000	0.997	0.003
Z95.3 Presence of xenogenic heart valve	0.000	0.997	0.003
Z59.1 Inadequate housing	0.000	0.997	0.003
W25.9 Unspecified place	0.003	0.997	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.997	0.003
Z63.6 Dependent relative needing care at home	0.000	0.997	0.003
Z63.5 Disruption of family by separation and divorce	0.000	0.997	0.003
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.997	0.003
Z59.7 Insufficient social insurance and welfare support	0.000	0.997	0.003
Z59.6 Low income	0.000	0.997	0.003
Z59.5 Extreme poverty	0.000	0.997	0.003
Z59.3 Problems related to living in residential institution	0.000	0.997	0.003
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
Z65 Problems related to other psychosocial circumstances	0.000	0.997	0.003
E30.9 Disorder of puberty, unspecified	0.000	0.997	0.002
E30.8 Other disorders of puberty	0.000	0.997	0.002
E30.1 Precocious puberty	0.000	0.997	0.002
E30.0 Delayed puberty	0.000	0.997	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.997	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.997	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.997	0.002
Z59.4 Lack of adequate food	0.000	0.997	0.003
O03.9 Complete or unspecified, without complication	0.003	0.997	0.000
N03 Chronic nephritic syndrome	0.000	0.997	0.003
E25.9 Adrenogenital disorder, unspecified	0.000	0.997	0.002
E25.8 Other adrenogenital disorders	0.000	0.997	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.997	0.002
E31.8 Other polyglandular dysfunction	0.000	0.997	0.002
E31.1 Polyglandular hyperfunction	0.000	0.997	0.002
N02.7 Diffuse crescentic glomerulonephritis	0.000	0.997	0.002
N02.6 Dense deposit disease	0.000	0.997	0.002
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.997	0.002
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.997	0.002
N04.9 Unspecified	0.000	0.997	0.003
Z62 Other problems related to upbringing	0.000	0.997	0.002
Z55 Problems related to education and literacy	0.000	0.997	0.002
E32.1 Abscess of thymus	0.000	0.997	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.997	0.002
N02.1 Focal and segmental glomerular lesions	0.000	0.997	0.002
Z01.6 Radiological examination, not elsewhere classified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.000	0.997	0.002
Y43.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
N07 Hereditary nephropathy, not elsewhere classified	0.000	0.997	0.002
N06 Isolated proteinuria with specified morphological lesion	0.000	0.997	0.002
N01 Rapidly progressive nephritic syndrome	0.000	0.997	0.002
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
Z64 Problems related to certain psychosocial circumstances	0.000	0.997	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.997	0.002
Z56 Problems related to employment and unemployment	0.000	0.997	0.002
R25.2 Cramp and spasm	0.000	0.997	0.003
Z63.4 Disappearance and death of family member	0.000	0.997	0.002
E32.9 Disease of thymus, unspecified	0.000	0.997	0.002
N00 Acute nephritic syndrome	0.000	0.997	0.002
Y43 Primarily systemic agents	0.000	0.998	0.002
N02.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N04.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
R14 Flatulence and related conditions	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
N04.8 Other	0.000	0.998	0.002
H92.1 Otorrhoea	0.000	0.998	0.002
Z61 Problems related to negative life events in childhood	0.000	0.998	0.002
N04.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N04.6 Dense deposit disease	0.000	0.998	0.002
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
N03.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N04.0 Minor glomerular abnormality	0.000	0.998	0.002
N70.1 Chronic salpingitis and oophoritis	0.002	0.998	0.000
N02.8 Other	0.000	0.998	0.002
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.998	0.002
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
N04.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
R10.0 Acute abdomen	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.998	0.002
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.998	0.002
Z65.4 Victim of crime and terrorism	0.000	0.998	0.002
Z65.2 Problems related to release from prison	0.000	0.998	0.002
Z65.1 Imprisonment and other incarceration	0.000	0.998	0.002
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.998	0.002
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
N03.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
R06.8 Other and unspecified abnormalities of breathing	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
N05 Unspecified nephritic syndrome	0.000	0.998	0.002
N03.8 Other	0.000	0.998	0.002
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N03.6 Dense deposit disease	0.000	0.998	0.002
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N03.0 Minor glomerular abnormality	0.000	0.998	0.002
Z65.3 Problems related to other legal circumstances	0.000	0.998	0.002
Z58 Problems related to physical environment	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
Y43.2 Antineoplastic natural products	0.000	0.998	0.002
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.998	0.002
Z55.8 Other problems relating to education and literacy	0.000	0.998	0.002
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.998	0.002
Z55.3 Underachievement in school	0.000	0.998	0.002
Z55.2 Failed examinations	0.000	0.998	0.002
Z55.1 Schooling unavailable and unattainable	0.000	0.998	0.002
Z55.0 Illiteracy and low-level literacy	0.000	0.998	0.002
Z56.0 Unemployment, unspecified	0.000	0.998	0.002
Z62.9 Problem related to upbringing, unspecified	0.000	0.998	0.002
Z62.8 Other specified problems related to upbringing	0.000	0.998	0.002
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.998	0.002
Z62.5 Other problems related to neglect in upbringing	0.000	0.998	0.002
Z62.4 Emotional neglect of child	0.000	0.998	0.002
Z62.3 Hostility towards and scapegoating of child	0.000	0.998	0.002
Z62.2 Institutional upbringing	0.000	0.998	0.002
Z62.1 Parental overprotection	0.000	0.998	0.002
Z62.0 Inadequate parental supervision and control	0.000	0.998	0.002
N01.9 Unspecified	0.000	0.998	0.002
N01.8 Other	0.000	0.998	0.002
N01.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N01.6 Dense deposit disease	0.000	0.998	0.002
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N01.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N01.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
N01.0 Minor glomerular abnormality	0.000	0.998	0.002
N06.9 Unspecified	0.000	0.998	0.002
N06.8 Other	0.000	0.998	0.002
N06.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N06.6 Dense deposit disease	0.000	0.998	0.002
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N06.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N06.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
N06.0 Minor glomerular abnormality	0.000	0.998	0.002
N07.9 Unspecified	0.000	0.998	0.002
N07.8 Other	0.000	0.998	0.002
N07.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N07.6 Dense deposit disease	0.000	0.998	0.002
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N07.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N07.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
N07.0 Minor glomerular abnormality	0.000	0.998	0.002
Z64.4 Discord with counsellors	0.000	0.998	0.002
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.1 Problems related to multiparity	0.000	0.998	0.002
U80.0 Penicillin resistant agent	0.000	0.998	0.002
Z56.5 Uncongenial work	0.000	0.998	0.002
Z56.2 Threat of job loss	0.000	0.998	0.002
Z56.1 Change of job	0.000	0.998	0.002
K04.7 Periapical abscess without sinus	0.002	0.998	0.000
N00.8 Other	0.000	0.998	0.002
N00.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N00.6 Dense deposit disease	0.000	0.998	0.002
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N00.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N00.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
N00.0 Minor glomerular abnormality	0.000	0.998	0.002
Z56.4 Discord with boss and workmates	0.000	0.998	0.002
Y43.9 Primarily systemic agent, unspecified	0.000	0.998	0.002
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.998	0.002
Y43.6 Enzymes, not elsewhere classified	0.000	0.998	0.002
Y43.5 Acidifying and alkalising agents	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.002
N19 Unspecified renal failure	0.002	0.998	0.000
Z56.7 Other and unspecified problems related to employment	0.000	0.998	0.002
Z56.6 Other physical and mental strain related to work	0.000	0.998	0.002
Z56.3 Stressful work schedule	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.000	0.998	0.002
D07.5 Prostate	0.002	0.998	0.000
N00.9 Unspecified	0.000	0.998	0.002
S89.8 Other specified injuries of lower leg	0.000	0.998	0.002
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.002
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.002
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.998	0.002
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.002
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.002
Z61.1 Removal from home in childhood	0.000	0.998	0.002
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.002
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
T84.0 Mechanical complication of internal joint prosthesis	0.002	0.998	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.998	0.002
R10 Abdominal and pelvic pain	0.002	0.998	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.998	0.002
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
Z61.8 Other negative life events in childhood	0.000	0.998	0.002
S89 Other and unspecified injuries of lower leg	0.000	0.998	0.002
N03.9 Unspecified	0.000	0.998	0.002
N05.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.002
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.998	0.002
J92 Pleural plaque	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N05.6 Dense deposit disease	0.000	0.998	0.002
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N05.0 Minor glomerular abnormality	0.000	0.998	0.002
Z58.5 Exposure to other pollution	0.000	0.998	0.002
S82.6 Fracture of lateral malleolus	0.000	0.998	0.002
Z58.9 Problem related to physical environment, unspecified	0.000	0.998	0.002
Z58.6 Inadequate drinking-water supply	0.000	0.998	0.002
Z58.4 Exposure to radiation	0.000	0.998	0.002
Z58.3 Exposure to soil pollution	0.000	0.998	0.002
Z58.2 Exposure to water pollution	0.000	0.998	0.002
Z58.0 Exposure to noise	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
N05.8 Other	0.000	0.998	0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
Z02.8 Other examinations for administrative purposes	0.002	0.998	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.000	0.998	0.002
S82.0 Fracture of patella	0.000	0.998	0.002
M94.88 Other specified disorders of cartilage (Other)	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.001
T39.0 Salicylates	0.000	0.998	0.002
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
W25 Contact with sharp glass	0.002	0.998	0.000
K05.1 Chronic gingivitis	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.001
J45 Asthma	0.000	0.998	0.002
S89.7 Multiple injuries of lower leg	0.000	0.998	0.002
S89.1 Other specified injuries of lower leg	0.000	0.998	0.002
S89.0 Multiple injuries of lower leg	0.000	0.998	0.002
M19.01 Primary arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.998	0.001
E21.2 Other hyperparathyroidism	0.000	0.998	0.001
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.001
H92.2 Otorrhagia	0.000	0.998	0.001
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.001	0.998	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.001	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
E88 Other metabolic disorders	0.002	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.001	0.998	0.000
W25.2 School, other institution and public administrative area	0.001	0.998	0.000
Z58.1 Exposure to air pollution	0.001	0.998	0.001
W25.8 Other specified place	0.001	0.998	0.000
T21 Burn and corrosion of trunk	0.001	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.001	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.001	0.998	0.000
E88.9 Metabolic disorder, unspecified	0.001	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.001	0.998	0.000
Y43.4 Immunosuppressive agents	0.001	0.998	0.001
N60.3 Fibrosclerosis of breast	0.001	0.998	0.000
W25.6 Industrial and construction area	0.001	0.998	0.000
W25.5 Trade and service area	0.001	0.998	0.000
W25.1 Residential institution	0.001	0.998	0.000
W25.0 Home	0.001	0.998	0.000
W25.7 Farm	0.001	0.998	0.000
W25.4 Street and highway	0.001	0.998	0.000
W25.3 Sports and athletics area	0.001	0.998	0.000
Z60 Problems related to social environment	0.000	0.998	0.001
S82.01 Fracture of patella (open)	0.000	0.998	0.001
S82.51 Fracture of medial malleolus (open)	0.000	0.998	0.001
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.001	0.998	0.000
C45.9 Mesothelioma, unspecified	0.001	0.998	0.000
J45.8 Mixed asthma	0.000	0.998	0.001
N70.9 Salpingitis and oophoritis, unspecified	0.001	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.001
S82 Fracture of lower leg, including ankle	0.000	0.999	0.001
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
I49.5 Sick sinus syndrome	0.000	0.999	0.001
S82.2 Fracture of shaft of tibia	0.000	0.999	0.001
E88.8 Other specified metabolic disorders	0.001	0.999	0.000
J06.9 Acute upper respiratory infection, unspecified	0.001	0.999	0.000
N60.9 Benign mammary dysplasia, unspecified	0.001	0.999	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.999	0.001
O80 Single spontaneous delivery	0.001	0.999	0.000
E88.3 Tumour lysis syndrome	0.001	0.999	0.000
J45.1 Nonallergic asthma	0.000	0.999	0.001
S82.20 Fracture of shaft of tibia (closed)	0.000	0.999	0.001
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.999	0.001
T92.2 Sequelae of fracture at wrist and hand level	0.001	0.999	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.999	0.001
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.999	0.001
E88.2 Lipomatosis, not elsewhere classified	0.001	0.999	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.001	0.999	0.000
N05.9 Unspecified	0.000	0.999	0.001
T21.3 Burn of third degree of trunk	0.001	0.999	0.000
N70 Salpingitis and oophoritis	0.001	0.999	0.000
N39.4 Other specified urinary incontinence	0.000	0.999	0.001
R87.9 Unspecified abnormal finding	0.000	0.999	0.001
S82.9 Fracture of lower leg, part unspecified	0.000	0.999	0.001
S82.7 Multiple fractures of lower leg	0.000	0.999	0.001
T21.7 Corrosion of third degree of trunk	0.001	0.999	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.999	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.999	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.999	0.000
T21.1 Burn of first degree of trunk	0.001	0.999	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.001	0.999	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
C85.1 B-cell lymphoma, unspecified	0.001	0.999	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.999	0.000
K50.8 Other Crohn's disease	0.001	0.999	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.999	0.001
W25.09 Contact with sharp glass; Home; During unspecified activity	0.001	0.999	0.000
W25.03 Contact with sharp glass; Home; While engaged in other types of work	0.001	0.999	0.000
W25.18 Contact with sharp glass; Residential institution;While engaged in other specified activities	0.001	0.999	0.000
W25.52 Contact with sharp glass; Trade and service area;While working for income	0.001	0.999	0.000
W25.62 Contact with sharp glass; Industrial and construction area ;While working for income	0.001	0.999	0.000
H54.7 Unspecified visual loss	0.001	0.999	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.999	0.001
Z60.4 Social exclusion and rejection	0.000	0.999	0.001
Z60.3 Acculturation difficulty	0.000	0.999	0.001
Z60.1 Atypical parenting situation	0.000	0.999	0.001
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.999	0.001
T92 Sequelae of injuries of upper limb	0.001	0.999	0.000
M81.9 Osteoporosis, unspecified	0.000	0.999	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.999	0.001
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.999	0.001
S32.10 Fracture of sacrum (closed)	0.000	0.999	0.001
S82.70 Multiple fractures of lower leg (closed)	0.000	0.999	0.001
E21.0 Primary hyperparathyroidism	0.000	0.999	0.001
O80.1 Spontaneous breech delivery	0.001	0.999	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.001	0.999	0.000
K50 Crohn's disease [regional enteritis]	0.001	0.999	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.999	0.001
E88.1 Lipodystrophy, not elsewhere classified	0.001	0.999	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.001	0.999	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.999	0.001
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.001	0.999	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.001	0.999	0.000
Z60.8 Other problems related to social environment	0.000	0.999	0.001
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.999	0.001
S82.71 Multiple fractures of lower leg (open)	0.000	0.999	0.001
N60.4 Mammary duct ectasia	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations