TreeWAS – Variant ID: rs4378954

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68 Other coagulation defects	0.083	0.917	0.000
D68.2 Hereditary deficiency of other clotting factors	0.082	0.918	0.000
D68.8 Other specified coagulation defects	0.080	0.920	0.000
D68.6 Other Thrombophilia	0.072	0.928	0.000
D68.5 Primary Thrombophilia	0.070	0.930	0.000
D68.0 Von Willebrand's disease	0.069	0.931	0.000
D68.4 Acquired coagulation factor deficiency	0.066	0.934	0.000
D68.9 Coagulation defect, unspecified	0.064	0.936	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.061	0.939	0.000
D68.1 Hereditary factor XI deficiency	0.057	0.943	0.000
K74.6 Other and unspecified cirrhosis of liver	0.036	0.964	0.000
K74 Fibrosis and cirrhosis of liver	0.032	0.968	0.000
K74.0 Hepatic fibrosis	0.030	0.970	0.000
K74.5 Biliary cirrhosis, unspecified	0.027	0.973	0.000
K74.1 Hepatic sclerosis	0.024	0.976	0.000
K74.4 Secondary biliary cirrhosis	0.023	0.977	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.023	0.977	0.000
K74.3 Primary biliary cirrhosis	0.023	0.977	0.000
K70-K77 Diseases of liver	0.017	0.983	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.017	0.983	0.000
K76 Other diseases of liver	0.016	0.984	0.000
K70 Alcoholic liver disease	0.016	0.984	0.000
K76.6 Portal hypertension	0.015	0.985	0.000
K70.4 Alcoholic hepatic failure	0.015	0.985	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.014	0.986	0.000
K71 Toxic liver disease	0.013	0.987	0.000
K76.3 Infarction of liver	0.012	0.987	0.000
K76.7 Hepatorenal syndrome	0.012	0.987	0.000
K70.3 Alcoholic cirrhosis of liver	0.012	0.988	0.000
K77 Liver disorders in diseases classified elsewhere	0.012	0.988	0.000
K76.9 Liver disease, unspecified	0.012	0.988	0.000
K76.8 Other specified diseases of liver	0.012	0.988	0.000
K76.1 Chronic passive congestion of liver	0.012	0.988	0.000
K76.5 Hepatic veno-occlusive disease	0.012	0.988	0.000
K76.4 Peliosis hepatis	0.012	0.988	0.000
K76.2 Central haemorrhagic necrosis of liver	0.012	0.988	0.000
K73 Chronic hepatitis, not elsewhere classified	0.012	0.988	0.000
D67 Hereditary factor IX deficiency	0.011	0.988	0.000
K70.0 Alcoholic fatty liver	0.011	0.988	0.000
D66 Hereditary factor VIII deficiency	0.011	0.989	0.000
K70.1 Alcoholic hepatitis	0.011	0.989	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.011	0.989	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.011	0.989	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.010	0.990	0.000
K70.9 Alcoholic liver disease, unspecified	0.010	0.990	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.010	0.990	0.000
K71.9 Toxic liver disease, unspecified	0.010	0.990	0.000
K71.8 Toxic liver disease with other disorders of liver	0.010	0.990	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.010	0.990	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.010	0.990	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.010	0.990	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.010	0.990	0.000
K71.2 Toxic liver disease with acute hepatitis	0.010	0.990	0.000
K71.0 Toxic liver disease with cholestasis	0.009	0.991	0.000
K73.9 Chronic hepatitis, unspecified	0.009	0.991	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.009	0.991	0.000
D06.9 Cervix, unspecified	0.009	0.991	0.000
O26.8 Other specified pregnancy-related conditions	0.009	0.991	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.009	0.991	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.009	0.991	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.009	0.991	0.000
K75 Other inflammatory liver diseases	0.008	0.992	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
K29.1 Other acute gastritis	0.008	0.992	0.000
Z51.3 Blood transfusion without reported diagnosis	0.000	0.992	0.008
K72 Hepatic failure, not elsewhere classified	0.007	0.992	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.007	0.993	0.000
K75.9 Inflammatory liver disease, unspecified	0.007	0.993	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.007	0.993	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.007	0.993	0.000
O26.2 Pregnancy care of habitual aborter	0.007	0.993	0.000
K75.2 Nonspecific reactive hepatitis	0.006	0.994	0.000
K75.1 Phlebitis of portal vein	0.006	0.994	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.006	0.994	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O26.0 Excessive weight gain in pregnancy	0.005	0.995	0.000
K75.8 Other specified inflammatory liver diseases	0.005	0.995	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.005	0.995	0.000
O26.4 Herpes gestationis	0.005	0.995	0.000
O26.1 Low weight gain in pregnancy	0.005	0.995	0.000
O26.5 Maternal hypotension syndrome	0.005	0.995	0.000
K72.9 Hepatic failure, unspecified	0.005	0.995	0.000
K72.1 Chronic hepatic failure	0.005	0.995	0.000
K75.4 Autoimmune hepatitis	0.005	0.995	0.000
O26.9 Pregnancy-related condition, unspecified	0.005	0.995	0.000
D06 Carcinoma in situ of cervix uteri	0.005	0.995	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.995	0.005
D69 Purpura and other haemorrhagic conditions	0.003	0.996	0.001
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.996	0.004
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
N89.8 Other specified noninflammatory disorders of vagina	0.004	0.996	0.000
K11.2 Sialoadenitis	0.004	0.996	0.000
D06.0 Endocervix	0.004	0.996	0.000
K11.5 Sialolithiasis	0.004	0.996	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.996	0.004
K72.0 Acute and subacute hepatic failure	0.003	0.996	0.001
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
D06.7 Other parts of cervix	0.003	0.996	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.996	0.004
K75.0 Abscess of liver	0.003	0.996	0.001
D06.1 Exocervix	0.003	0.996	0.000
C62.9 Testis, unspecified	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.003	0.997	0.001
D69.2 Other nonthrombocytopenic purpura	0.002	0.997	0.001
C90.0 Multiple myeloma	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.002	0.997	0.001
D69.0 Allergic purpura	0.002	0.997	0.001
K11 Diseases of salivary glands	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.002	0.997	0.001
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.997	0.003
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
R09.1 Pleurisy	0.000	0.997	0.003
D69.9 Haemorrhagic condition, unspecified	0.002	0.997	0.001
K11.9 Disease of salivary gland, unspecified	0.003	0.997	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K85.1 Biliary acute pancreatitis	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.002	0.997	0.001
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
L89.1 Stage II decubitus ulcer	0.000	0.997	0.003
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.003	0.997	0.000
C85.0 Lymphosarcoma	0.000	0.997	0.003
K11.3 Abscess of salivary gland	0.003	0.997	0.000
K11.7 Disturbances of salivary secretion	0.003	0.997	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.997	0.003
K11.6 Mucocele of salivary gland	0.003	0.997	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.997	0.003
I27.8 Other specified pulmonary heart diseases	0.000	0.997	0.003
J45.0 Predominantly allergic asthma	0.003	0.997	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.997	0.003
K11.4 Fistula of salivary gland	0.003	0.997	0.000
K85.9 Acute pancreatitis, unspecified	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K11.1 Hypertrophy of salivary gland	0.003	0.997	0.000
K11.0 Atrophy of salivary gland	0.002	0.997	0.000
S00.0 Superficial injury of scalp	0.003	0.997	0.000
K85 Acute pancreatitis	0.003	0.997	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.997	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.997	0.003
I77.1 Stricture of artery	0.000	0.997	0.003
K85.8 Other acute pancreatitis	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
K13.0 Diseases of lips	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I26 Pulmonary embolism	0.000	0.998	0.002
G47.3 Sleep apnoea	0.000	0.998	0.002
L05.9 Pilonidal cyst without abscess	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R09.2 Respiratory arrest	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
C62 Malignant neoplasm of testis	0.000	0.998	0.002
C62.1 Descended testis	0.000	0.998	0.002
I27 Other pulmonary heart diseases	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
T86.0 Bone-marrow transplant rejection	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
R68.8 Other specified general symptoms and signs	0.000	0.998	0.002
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.998	0.002
G70.0 Myasthenia gravis	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.002	0.998	0.000
I61 Intracerebral haemorrhage	0.002	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.000	0.998	0.002
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
C62.0 Undescended testis	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
K31.9 Disease of stomach and duodenum, unspecified	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.998	0.000
R09.3 Abnormal sputum	0.000	0.998	0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
L89 Decubitus ulcer	0.000	0.998	0.002
O22 Venous complications in pregnancy	0.002	0.998	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
L89.2 Stage III decubitus ulcer	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.998	0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.998	0.002
X49.9 Unspecified place	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
R85.5 Abnormal microbiological findings	0.000	0.998	0.002
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.998	0.002
T86 Failure and rejection of transplanted organs and tissues	0.000	0.998	0.002
M62.88 Other specified disorders of muscle (Other)	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
R94.3 Abnormal results of cardiovascular function studies	0.000	0.998	0.002
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.998	0.002
N48.2 Other inflammatory disorders of penis	0.000	0.998	0.002
T86.4 Liver transplant failure and rejection	0.000	0.998	0.002
T86.1 Kidney transplant failure and rejection	0.000	0.998	0.002
H65 Nonsuppurative otitis media	0.000	0.998	0.002
H90 Conductive and sensorineural hearing loss	0.000	0.998	0.002
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.001	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.001	0.998	0.000
O95 Obstetric death of unspecified cause	0.001	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.001	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.001	0.998	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.001	0.998	0.000
D57 Sickle-cell disorders	0.001	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.001
S82.20 Fracture of shaft of tibia (closed)	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
O22.1 Genital varices in pregnancy	0.001	0.998	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.002	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.998	0.002
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.001	0.998	0.000
I77 Other disorders of arteries and arterioles	0.000	0.998	0.002
O28 Abnormal findings on antenatal screening of mother	0.001	0.998	0.000
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
O22.9 Venous complication in pregnancy, unspecified	0.001	0.998	0.000
O22.8 Other venous complications in pregnancy	0.001	0.998	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.001	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.001	0.998	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.001	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.001	0.998	0.000
I28 Other diseases of pulmonary vessels	0.000	0.998	0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.001
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.001	0.998	0.000
H65.3 Chronic mucoid otitis media	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.001	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
C57.0 Fallopian tube	0.000	0.998	0.001
D57.1 Sickle-cell anaemia without crisis	0.001	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.001	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.001	0.998	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.001	0.998	0.000
O29.6 Failed or difficult intubation during pregnancy	0.001	0.998	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.001	0.998	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.001	0.998	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.001	0.998	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.001	0.998	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.001	0.998	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.001	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.001	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.001	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.001
I28.8 Other specified diseases of pulmonary vessels	0.000	0.998	0.001
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.001	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.001
D59 Acquired haemolytic anaemia	0.001	0.998	0.000
J98.4 Other disorders of lung	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.001	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
T86.3 Heart-lung transplant failure and rejection	0.000	0.998	0.001
T86.2 Heart transplant failure and rejection	0.000	0.998	0.001
H65.0 Acute serous otitis media	0.000	0.999	0.001
J84.0 Alveolar and parietoalveolar conditions	0.000	0.999	0.001
R10.3 Pain localised to other parts of lower abdomen	0.000	0.999	0.001
N62 Hypertrophy of breast	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.999	0.001
D58.2 Other haemoglobinopathies	0.001	0.999	0.000
E10.9 Without complications	0.000	0.999	0.001
G57.6 Lesion of plantar nerve	0.000	0.999	0.001
H18.9 Disorder of cornea, unspecified	0.001	0.999	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.999	0.001
H90.2 Conductive hearing loss, unspecified	0.000	0.999	0.001
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.001	0.999	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.001	0.999	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.001	0.999	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.001	0.999	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.001	0.999	0.000
O96.9 Death from unspecified obstetric cause	0.001	0.999	0.000
O96.1 Death from indirect obstetric cause	0.001	0.999	0.000
O96.0 Death from direct obstetric cause	0.001	0.999	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.001	0.999	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.001	0.999	0.000
O97.0 Death from sequelae of direct obstetric cause	0.001	0.999	0.000
D56 Thalassaemia	0.001	0.999	0.000
D60-D64 Aplastic and other anaemias	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
D57.8 Other sickle-cell disorders	0.001	0.999	0.000
D57.3 Sickle-cell trait	0.001	0.999	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.999	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.999	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
H57.8 Other specified disorders of eye and adnexa	0.000	0.999	0.001
I77.2 Rupture of artery	0.000	0.999	0.001
O21.8 Other vomiting complicating pregnancy	0.001	0.999	0.000
C51 Malignant neoplasm of vulva	0.000	0.999	0.001
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.999	0.001
K86.8 Other specified diseases of pancreas	0.001	0.999	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.999	0.001
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.999	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.999	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Z90.5 Acquired absence of kidney	0.001	0.999	0.000
O30 Multiple gestation	0.001	0.999	0.000
C51.1 Labium minus	0.000	0.999	0.001
D69.6 Thrombocytopenia, unspecified	0.001	0.999	0.001
I77.5 Necrosis of artery	0.000	0.999	0.001
I77.4 Coeliac artery compression syndrome	0.000	0.999	0.001
I77.3 Arterial fibromuscular dysplasia	0.000	0.999	0.001
L98.0 Pyogenic granuloma	0.001	0.999	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.999	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.999	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.999	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.999	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.999	0.001
O24 Diabetes mellitus in pregnancy	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.999	0.001
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
C90.2 Plasmacytoma, extramedullary	0.001	0.999	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.999	0.000
D58.1 Hereditary elliptocytosis	0.001	0.999	0.000
I28.1 Aneurysm of pulmonary artery	0.000	0.999	0.001
L89.3 Stage IV decubitus ulcer	0.000	0.999	0.001
O72.1 Other immediate postpartum haemorrhage	0.001	0.999	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
T40.2 Other opioids	0.001	0.999	0.000
D51 Vitamin B12 deficiency anaemia	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.999	0.001
M24.07 Loose body in joint (Ankle and foot)	0.000	0.999	0.001
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.001	0.999	0.000
S82.21 Fracture of shaft of tibia (open)	0.001	0.999	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.999	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
I61.8 Other intracerebral haemorrhage	0.001	0.999	0.000
O21.9 Vomiting of pregnancy, unspecified	0.001	0.999	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.999	0.001
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999	0.000
K86 Other diseases of pancreas	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.999	0.001
C92.4 Acute promyelocytic leukaemia	0.001	0.999	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.999	0.001
D80-D89 Certain disorders involving the immune mechanism	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.999	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.999	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.999	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.999	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
O30.1 Triplet pregnancy	0.001	0.999	0.000
O86.4 Pyrexia of unknown origin following delivery	0.001	0.999	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.999	0.001
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.999	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.999	0.001
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.999	0.001
M62.8 Other specified disorders of muscle	0.000	0.999	0.001
N75.0 Cyst of Bartholin's gland	0.000	0.999	0.001
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.999	0.000
O73.0 Retained placenta, without haemorrhage	0.001	0.999	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
C92 Myeloid leukaemia	0.001	0.999	0.000
E27 Other disorders of adrenal gland	0.000	0.999	0.001
M79.60 Pain in limb (Multiple sites)	0.000	0.999	0.001
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
D56.8 Other thalassaemias	0.001	0.999	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.999	0.000
D56.2 Delta-beta thalassaemia	0.001	0.999	0.000
D56.0 Alpha thalassaemia	0.001	0.999	0.000
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.999	0.001
H65.2 Chronic serous otitis media	0.000	0.999	0.001
H65.1 Other acute nonsuppurative otitis media	0.000	0.999	0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.999	0.001
L85.9 Epidermal thickening, unspecified	0.001	0.999	0.000
L85.8 Other specified epidermal thickening	0.001	0.999	0.000
N04.9 Unspecified	0.000	0.999	0.001
O66.4 Failed trial of labour, unspecified	0.001	0.999	0.000
O66.2 Obstructed labour due to unusually large foetus	0.001	0.999	0.000
T90.9 Sequelae of unspecified injury of head	0.001	0.999	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.999	0.001
O66 Other obstructed labour	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
C51.8 Overlapping lesion of vulva	0.000	0.999	0.001
C51.2 Clitoris	0.000	0.999	0.001
C92.5 Acute myelomonocytic leukaemia	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
H18.3 Changes in corneal membranes	0.001	0.999	0.000
M88.9 Paget's disease of bone, unspecified	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.999	0.000
O30.9 Multiple gestation, unspecified	0.001	0.999	0.000
O30.8 Other multiple gestation	0.001	0.999	0.000
O30.2 Quadruplet pregnancy	0.001	0.999	0.000
T90.5 Sequelae of intracranial injury	0.001	0.999	0.000
T90 Sequelae of injuries of head	0.001	0.999	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
C92.9 Myeloid leukaemia, unspecified	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.001	0.999	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.999	0.000
I77.6 Arteritis, unspecified	0.000	0.999	0.001
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.999	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.999	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.999	0.000
O66.8 Other specified obstructed labour	0.001	0.999	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.001	0.999	0.000
T90.3 Sequelae of injury of cranial nerves	0.001	0.999	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
C57.9 Female genital organ, unspecified	0.000	0.999	0.001
C57.7 Other specified female genital organs	0.000	0.999	0.001
C57.4 Uterine adnexa, unspecified	0.000	0.999	0.001
C57.3 Parametrium	0.000	0.999	0.001
C57.2 Round ligament	0.000	0.999	0.001
C57.1 Broad ligament	0.000	0.999	0.001
C92.2 Subacute myeloid leukaemia	0.001	0.999	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
D60.8 Other acquired pure red cell aplasias	0.001	0.999	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations