TreeWAS – Variant ID: rs4389974

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S22 Fracture of rib(s), sternum and thoracic spine	0.040	0.960	0.000
S22.30 Fracture of rib (closed)	0.039	0.961	0.000
S22.3 Fracture of rib	0.039	0.961	0.000
S22.40 Multiple fractures of ribs (closed)	0.039	0.961	0.000
S22.4 Multiple fractures of ribs	0.039	0.961	0.000
S22.2 Fracture of sternum	0.034	0.966	0.000
S22.5 Flail chest	0.032	0.968	0.000
S22.20 Fracture of sternum (closed)	0.031	0.969	0.000
S22.1 Multiple fractures of thoracic spine	0.030	0.970	0.000
S22.0 Fracture of thoracic vertebra	0.029	0.971	0.000
S22.9 Fracture of bony thorax, part unspecified	0.028	0.971	0.000
S22.8 Fracture of other parts of bony thorax	0.028	0.971	0.000
S22.31 Fracture of rib (open)	0.028	0.972	0.000
S22.41 Multiple fractures of ribs (open)	0.028	0.972	0.000
S22.50 Flail chest (closed)	0.027	0.973	0.000
S22.21 Fracture of sternum (open)	0.025	0.975	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.024	0.976	0.000
S22.51 Flail chest (open)	0.023	0.977	0.000
S27 Injury of other and unspecified intrathoracic organs	0.023	0.977	0.000
S27.3 Other injuries of lung	0.022	0.978	0.000
S20-S29 Injuries to the thorax	0.022	0.978	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.022	0.978	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.022	0.978	0.000
S22.01 Fracture of thoracic vertebra (open)	0.021	0.979	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.021	0.979	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.021	0.979	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.021	0.979	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.021	0.979	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.021	0.979	0.000
S27.1 Traumatic haemothorax	0.020	0.980	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.020	0.980	0.000
S27.0 Traumatic pneumothorax	0.020	0.980	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.018	0.982	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.017	0.983	0.000
S27.9 Injury of unspecified intrathoracic organ	0.017	0.983	0.000
S27.7 Multiple injuries of intrathoracic organs	0.017	0.983	0.000
S27.6 Injury of pleura	0.017	0.983	0.000
S27.5 Injury of thoracic trachea	0.017	0.983	0.000
S27.4 Injury of bronchus	0.017	0.983	0.000
S27.2 Traumatic heamopneumothorax	0.017	0.983	0.000
S27.8 Injury of other specified intrathoracic organs	0.017	0.983	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.016	0.984	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.984	0.016
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.016	0.984	0.000
S26 Injury of heart	0.016	0.984	0.000
S25 Injury of blood vessels of thorax	0.016	0.984	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.016	0.984	0.000
S21 Open wound of thorax	0.015	0.985	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.985	0.015
S24 Injury of nerves and spinal cord at thorax level	0.015	0.985	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.015	0.985	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.014	0.986	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.014	0.986	0.000
S29 Other and unspecified injuries of thorax	0.013	0.987	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.012	0.988	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.012	0.988	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.988	0.012
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.012	0.988	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.012	0.988	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.012	0.988	0.000
S23.4 Sprain and strain of ribs and sternum	0.012	0.988	0.000
S23.3 Sprain and strain of thoracic spine	0.012	0.988	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.012	0.988	0.000
S23.1 Dislocation of thoracic vertebra	0.012	0.988	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.012	0.988	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.012	0.988	0.000
S25.8 Injury of other blood vessels of thorax	0.012	0.988	0.000
S25.7 Injury of multiple blood vessels of thorax	0.012	0.988	0.000
S25.5 Injury of intercostal blood vessels	0.012	0.988	0.000
S25.4 Injury of pulmonary blood vessels	0.012	0.988	0.000
S25.3 Injury of innominate or subclavian vein	0.012	0.988	0.000
S25.2 Injury of superior vena cava	0.012	0.988	0.000
S25.1 Injury of innominate or subclavian artery	0.012	0.988	0.000
S25.0 Injury of thoracic aorta	0.012	0.988	0.000
S26.9 Injury of heart, unspecified	0.012	0.988	0.000
S26.8 Other injuries of heart	0.012	0.988	0.000
S26.0 Injury of heart with haemopericardium	0.012	0.988	0.000
S28.1 Traumatic amputation of part of thorax	0.012	0.988	0.000
S28.0 Crushed chest	0.012	0.988	0.000
S21.9 Open wound of thorax, part unspecified	0.012	0.988	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.989	0.011
K08.3 Retained dental root	0.000	0.989	0.011
S21.8 Open wound of other parts of thorax	0.011	0.989	0.000
S21.7 Multiple open wounds of thoracic wall	0.011	0.989	0.000
S21.0 Open wound of breast	0.011	0.989	0.000
S24.6 Injury of unspecified nerve of thorax	0.011	0.989	0.000
S24.5 Injury of other nerves of thorax	0.011	0.989	0.000
S24.4 Injury of thoracic sympathetic nerves	0.011	0.989	0.000
S24.3 Injury of peripheral nerves of thorax	0.011	0.989	0.000
S24.2 Injury of nerve root of thoracic spine	0.011	0.989	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.011	0.989	0.000
S21.1 Open wound of front wall of thorax	0.010	0.989	0.000
S21.2 Open wound of back wall of thorax	0.010	0.990	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.009	0.990	0.000
S29.7 Multiple injuries of thorax	0.009	0.990	0.000
S29.8 Other specified injuries of thorax	0.009	0.990	0.000
S29.0 Injury of muscle and tendon at thorax level	0.009	0.991	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.991	0.009
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.991	0.009
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.008	0.991	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.008	0.991	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.008	0.991	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.008	0.991	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.008	0.991	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.008	0.991	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.991	0.009
S01.0 Open wound of scalp	0.000	0.992	0.008
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.992	0.008
K29.1 Other acute gastritis	0.000	0.992	0.008
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.993	0.007
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.007	0.993	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.993	0.007
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.993	0.007
M54.36 Sciatica (Lumbar region)	0.007	0.993	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.993	0.007
A04.5 Campylobacter enteritis	0.000	0.993	0.007
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.993	0.007
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.993	0.007
T91.1 Sequelae of fracture of spine	0.000	0.993	0.007
Z57.2 Occupational exposure to dust	0.007	0.993	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.993	0.006
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.993	0.006
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.993	0.006
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.993	0.006
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.993	0.006
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.993	0.006
S29.9 Unspecified injury of thorax	0.006	0.993	0.000
S20 Superficial injury of thorax	0.006	0.994	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.994	0.006
A04 Other bacterial intestinal infections	0.000	0.994	0.006
T91 Sequelae of injuries of neck and trunk	0.000	0.994	0.006
I69.0 Sequelae of subarachnoid haemorrhage	0.006	0.994	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.994	0.006
H92.1 Otorrhoea	0.000	0.994	0.006
T91.3 Sequelae of injury of spinal cord	0.000	0.994	0.006
N18.9 Chronic renal failure, unspecified	0.000	0.994	0.006
A04.4 Other intestinal Escherichia coli infections	0.000	0.995	0.005
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.995	0.005
S20.7 Multiple superficial injuries of thorax	0.005	0.995	0.000
S20.0 Contusion of breast	0.005	0.995	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.005	0.995	0.000
S20.1 Other and unspecified superficial injuries of breast	0.004	0.995	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.995	0.005
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.995	0.005
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.995	0.005
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.995	0.005
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.995	0.005
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.995	0.005
S20.4 Other superficial injuries of back wall of thorax	0.004	0.995	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.995	0.005
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.995	0.005
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.995	0.005
A04.9 Bacterial intestinal infection, unspecified	0.000	0.996	0.004
F31 Bipolar affective disorder	0.000	0.996	0.004
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
S20.3 Other superficial injuries of front wall of thorax	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.996	0.004
M80 Osteoporosis with pathological fracture	0.000	0.996	0.004
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.000	0.996	0.004
O66 Other obstructed labour	0.000	0.996	0.004
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.996	0.004
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.004	0.996	0.000
N45 Orchitis and epididymitis	0.004	0.996	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.004	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.004	0.996	0.000
I69 Sequelae of cerebrovascular disease	0.004	0.996	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.996	0.004
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.996	0.003
H74.8 Other specified disorders of middle ear and mastoid	0.004	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.996	0.003
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.996	0.003
F41.2 Mixed anxiety and depressive disorder	0.003	0.997	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.003	0.997	0.000
O66.4 Failed trial of labour, unspecified	0.000	0.997	0.003
Z57 Occupational exposure to risk-factors	0.003	0.997	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
C32.0 Glottis	0.003	0.997	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.997	0.003
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
H53.8 Other visual disturbances	0.000	0.997	0.003
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.997	0.003
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.997	0.003
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.997	0.003
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.997	0.003
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
Z56.6 Other physical and mental strain related to work	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
O66.9 Obstructed labour, unspecified	0.000	0.997	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.997	0.003
S20.2 Contusion of thorax	0.003	0.997	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.997	0.003
O66.1 Obstructed labour due to locked twins	0.000	0.997	0.003
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.003	0.997	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.003
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
S32.1 Fracture of sacrum	0.003	0.997	0.000
O66.8 Other specified obstructed labour	0.000	0.997	0.003
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
M80.8 Other osteoporosis with pathological fracture	0.000	0.997	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.997	0.003
Z57.9 Occupational exposure to unspecified risk-factor	0.003	0.997	0.000
Z57.7 Occupational exposure to vibration	0.003	0.997	0.000
Z57.6 Occupational exposure to extreme temperature	0.003	0.997	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.003	0.997	0.000
Z57.1 Occupational exposure to radiation	0.003	0.997	0.000
Z57.0 Occupational exposure to noise	0.003	0.997	0.000
H74.1 Adhesive middle ear disease	0.003	0.997	0.000
K29.3 Chronic superficial gastritis	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
F03 Unspecified dementia	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.997	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.997	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.997	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.997	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.997	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.997	0.003
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.002
D41.4 Bladder	0.000	0.997	0.003
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.997	0.000
E10.3 With ophthalmic complications	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
M25.57 Pain in joint (Ankle and foot)	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
S32.5 Fracture of pubis	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.998	0.002
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
E10.9 Without complications	0.002	0.998	0.000
M25.58 Pain in joint (Other)	0.002	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.000	0.998	0.002
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
Z58 Problems related to physical environment	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
Z65.8 Other specified problems related to psychosocial circumstances	0.002	0.998	0.000
E10.6 With other specified complications	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.002	0.998	0.001
Z58.1 Exposure to air pollution	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.998	0.002
C32.9 Larynx, unspecified	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.998	0.002
Q50.3 Other congenital malformations of ovary	0.000	0.998	0.002
Q50.2 Congenital torsion of ovary	0.000	0.998	0.002
Q50.1 Developmental ovarian cyst	0.000	0.998	0.002
Q50.0 Congenital absence of ovary	0.000	0.998	0.002
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.998	0.002
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.002	0.998	0.000
Z56.5 Uncongenial work	0.002	0.998	0.000
Z56.4 Discord with boss and workmates	0.002	0.998	0.000
Z56.2 Threat of job loss	0.002	0.998	0.000
Z56.1 Change of job	0.002	0.998	0.000
C32 Malignant neoplasm of larynx	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
S32.3 Fracture of ilium	0.002	0.998	0.000
Z56.7 Other and unspecified problems related to employment	0.002	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
S32.51 Fracture of pubis (open)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
H27.0 Aphakia	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.001	0.998	0.001
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.002	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.1 Problems related to multiparity	0.002	0.998	0.000
Z65.3 Problems related to other legal circumstances	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.001	0.998	0.001
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.002	0.998	0.000
M62.68 Muscle strain (Other)	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
E10.4 With neurological complications	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.002	0.998	0.000
Z65.4 Victim of crime and terrorism	0.002	0.998	0.000
Z65.2 Problems related to release from prison	0.002	0.998	0.000
Z65.1 Imprisonment and other incarceration	0.002	0.998	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
K62.7 Radiation proctitis	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.001	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.998	0.000
Z58.4 Exposure to radiation	0.002	0.998	0.000
Z58.3 Exposure to soil pollution	0.002	0.998	0.000
Z58.2 Exposure to water pollution	0.002	0.998	0.000
Z58.0 Exposure to noise	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M62.08 Diastasis of muscle (Other)	0.002	0.998	0.000
M62.46 Contracture of muscle (Lower leg)	0.002	0.998	0.000
M84.0 Malunion of fracture	0.000	0.998	0.002
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.000	0.998	0.002
M19.98 Arthrosis, unspecified (Other)	0.000	0.998	0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.002	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.998	0.002
E10.7 With multiple complications	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.000	0.998	0.002
M62.96 Disorder of muscle, unspecified (Lower leg)	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
I84.3 External thrombosed haemorrhoids	0.000	0.998	0.002
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
O14.2 HELLP syndrome	0.000	0.998	0.002
S32.31 Fracture of ilium (open)	0.001	0.998	0.000
C32.8 Overlapping lesion of larynx	0.002	0.998	0.000
C32.3 Laryngeal cartilage	0.002	0.998	0.000
C32.2 Subglottis	0.002	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.001	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
Q54.0 Hypospadias, balanic	0.000	0.998	0.002
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
M62.69 Muscle strain (Site unspecified)	0.001	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.998	0.000
M62.64 Muscle strain (Hand)	0.001	0.998	0.000
M62.63 Muscle strain (Forearm)	0.001	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.998	0.000
E10.0 With coma	0.002	0.998	0.000
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Z56.0 Unemployment, unspecified	0.001	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.001	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.998	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.998	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.998	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.998	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.998	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.998	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.998	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.998	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.998	0.000
M62.48 Contracture of muscle (Other)	0.001	0.998	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.998	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.998	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.998	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.998	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.998	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations