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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs440261
log Bayes Factor = 61.2793
Chromosome 6   position 32,198,056  (GRCh37) Explore rs440261 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E03 Other hypothyroidism
0.000 0.011 0.989
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.012 0.988
E10.4 With neurological complications
0.000 0.013 0.987
E14 Unspecified diabetes mellitus
0.000 0.013 0.987
E03.9 Hypothyroidism, unspecified
0.000 0.013 0.987
M06 Other rheumatoid arthritis
0.000 0.014 0.986
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.019 0.981
H36.0 Diabetic retinopathy
0.000 0.024 0.976
K90.0 Coeliac disease
0.000 0.025 0.975
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.025 0.975
L40.9 Psoriasis, unspecified
0.000 0.025 0.975
E10.2 With renal complications
0.000 0.028 0.972
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.045 0.955
E14.3 With ophthalmic complications
0.000 0.045 0.955
M06.3 Rheumatoid nodule
0.000 0.063 0.937
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.068 0.932
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.068 0.932
E10.5 With peripheral circulatory complications
0.000 0.076 0.924
E14.9 Without complications
0.000 0.090 0.910
E10.0 With coma
0.000 0.090 0.910
E06 Thyroiditis
0.000 0.112 0.888
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.121 0.879
E50-E64 Other nutritional deficiencies
0.000 0.122 0.878
E04 Other non-toxic goitre
0.000 0.134 0.866
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.151 0.849
M05-M14 Inflammatory polyarthropathies
0.000 0.159 0.841
M05 Seropositive rheumatoid arthritis
0.000 0.163 0.837
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.165 0.835
G37 Other demyelinating diseases of central nervous system
0.000 0.168 0.832
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.168 0.832
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.168 0.832
E10.6 With other specified complications
0.000 0.174 0.826
E06.3 Autoimmune thyroiditis
0.000 0.177 0.823
M06.4 Inflammatory polyarthropathy
0.000 0.180 0.820
M06.34 Rheumatoid nodule (Hand)
0.000 0.182 0.818
M06.0 Seronegative rheumatoid arthritis
0.000 0.200 0.800
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.213 0.787
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.221 0.779
E70-E90 Metabolic disorders
0.000 0.230 0.770
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.239 0.761
E86 Volume depletion
0.000 0.242 0.758
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.242 0.758
E04.0 Non-toxic diffuse goitre
0.000 0.243 0.757
E05.9 Thyrotoxicosis, unspecified
0.000 0.249 0.751
E10.8 With unspecified complications
0.000 0.252 0.748
E07 Other disorders of thyroid
0.000 0.253 0.747
E55 Vitamin D deficiency
0.000 0.259 0.741
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.259 0.741
E14.1 With ketoacidosis
0.000 0.265 0.735
E04.2 Non-toxic multinodular goitre
0.000 0.272 0.728
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.276 0.724
E14.8 With unspecified complications
0.000 0.277 0.723
H36 Retinal disorders in diseases classified elsewhere
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.288 0.712
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.289 0.711
E53 Deficiency of other B group vitamins
0.000 0.289 0.711
E03.5 Myxoedema coma
0.000 0.291 0.709
E03.4 Atrophy of thyroid (acquired)
0.000 0.291 0.709
E03.3 Postinfectious hypothyroidism
0.000 0.291 0.709
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.291 0.709
E05.5 Thyroid crisis or storm
0.000 0.292 0.708
E05.4 Thyrotoxicosis factitia
0.000 0.292 0.708
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.292 0.708
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.292 0.708
E14.7 With multiple complications
0.000 0.293 0.707
E14.6 With other specified complications
0.000 0.293 0.707
E14.5 With peripheral circulatory complications
0.000 0.293 0.707
E14.0 With coma
0.000 0.293 0.707
M06.8 Other specified rheumatoid arthritis
0.000 0.293 0.707
M06.2 Rheumatoid bursitis
0.000 0.293 0.707
M06.1 Adult-onset Still's disease
0.000 0.293 0.707
E61 Deficiency of other nutrient elements
0.000 0.295 0.705
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.298 0.702
E73 Lactose intolerance
0.000 0.299 0.701
E14.4 With neurological complications
0.000 0.307 0.693
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.328 0.672
M06.38 Rheumatoid nodule (Other)
0.000 0.328 0.672
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.328 0.672
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.328 0.672
M06.33 Rheumatoid nodule (Forearm)
0.000 0.328 0.672
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.328 0.672
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.328 0.672
E03.1 Congenital hypothyroidism without goitre
0.000 0.328 0.671
E05.8 Other thyrotoxicosis
0.000 0.332 0.668
E40-E46 Malnutrition
0.000 0.334 0.666
E73.9 Lactose intolerance, unspecified
0.000 0.348 0.652
L40 Psoriasis
0.000 0.349 0.651
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.353 0.647
E14.2 Withrenal complications
0.000 0.357 0.643
E55.9 Vitamin D deficiency, unspecified
0.000 0.357 0.643
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.360 0.640
E06.5 Other chronic thyroiditis
0.000 0.363 0.637
E06.4 Drug-induced thyroiditis
0.000 0.363 0.637
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.363 0.637
E06.1 Subacute thyroiditis
0.000 0.363 0.637
E06.0 Acute thyroiditis
0.000 0.363 0.637
E07.8 Other specified disorders of thyroid
0.000 0.364 0.636
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.366 0.634
G36 Other acute disseminated demyelination
0.000 0.370 0.630
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.371 0.629
E63 Other nutritional deficiencies
0.000 0.371 0.629
E56 Other vitamin deficiencies
0.000 0.371 0.629
E50 Vitamin A deficiency
0.000 0.371 0.629
E60 Dietary zinc deficiency
0.000 0.371 0.629
E59 Dietary selenium deficiency
0.000 0.371 0.629
E54 Ascorbic acid deficiency
0.000 0.371 0.629
E52 Niacin deficiency [pellagra]
0.000 0.371 0.629
E04.9 Non-toxic goitre, unspecified
0.000 0.376 0.624
E04.8 Other specified non-toxic goitre
0.000 0.379 0.621
E61.1 Iron deficiency
0.000 0.385 0.615
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.388 0.612
E51 Thiamine deficiency
0.000 0.391 0.609
E53.9 Vitamin B deficiency, unspecified
0.000 0.392 0.607
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.397 0.603
M08 Juvenile arthritis
0.000 0.397 0.603
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.399 0.601
E88 Other metabolic disorders
0.000 0.399 0.601
M05.8 Other seropositive rheumatoid arthritis
0.000 0.400 0.600
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.400 0.600
M05.2 Rheumatoid vasculitis
0.000 0.400 0.600
M05.1 Rheumatoid lung disease
0.000 0.400 0.600
M05.0 Felty's syndrome
0.000 0.400 0.600
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.400 0.600
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.401 0.599
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.401 0.599
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.401 0.599
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.401 0.599
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.401 0.599
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.401 0.599
G37.5 Concentric sclerosis [Balo]
0.000 0.403 0.597
G37.4 Subacute necrotising myelitis
0.000 0.403 0.597
G37.2 Central pontine myelinolysis
0.000 0.403 0.597
G37.1 Central demyelination of corpus callosum
0.000 0.403 0.597
G37.0 Diffuse sclerosis
0.000 0.403 0.597
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.405 0.594
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.412 0.588
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.412 0.588
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.412 0.588
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.412 0.588
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.412 0.588
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.412 0.588
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.412 0.588
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.412 0.588
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.413 0.587
E16.1 Other hypoglycaemia
0.000 0.414 0.586
E06.9 Thyroiditis, unspecified
0.000 0.419 0.580
M14 Arthropathies in other diseases classified elsewhere
0.000 0.420 0.580
M12 Other specific arthropathies
0.000 0.421 0.579
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.426 0.574
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.426 0.574
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.426 0.574
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.426 0.574
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.426 0.574
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.426 0.574
E89.0 Postprocedural hypothyroidism
0.000 0.431 0.569
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.432 0.568
E58 Dietary calcium deficiency
0.000 0.436 0.564
E79 Disorders of purine and pyrimidine metabolism
0.000 0.444 0.556
E77 Disorders of glycoprotein metabolism
0.000 0.448 0.552
E76 Disorders of glycosaminoglycan metabolism
0.000 0.448 0.552
E72 Other disorders of amino-acid metabolism
0.000 0.448 0.552
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.448 0.552
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.448 0.552
E84 Cystic fibrosis
0.000 0.450 0.550
E07.1 Dyshormogenetic goitre
0.000 0.464 0.536
E07.0 Hypersecretion of calcitonin
0.000 0.464 0.536
M10 Gout
0.000 0.464 0.536
H30-H36 Disorders of choroid and retina
0.000 0.465 0.535
E11 Non-insulin-dependent diabetes mellitus
0.000 0.468 0.532
E55.0 Rickets, active
0.000 0.469 0.531
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.474 0.526
E03.8 Other specified hypothyroidism
0.000 0.477 0.522
L40.5 Arthropathic psoriasis
0.000 0.478 0.522
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.479 0.521
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.484 0.516
J33.0 Polyp of nasal cavity
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E74 Other disorders of carbohydrate metabolism
0.000 0.487 0.513
J33 Nasal polyp
0.000 0.488 0.512
E53.1 Pyridoxine deficiency
0.000 0.490 0.510
E53.0 Riboflavin deficiency
0.000 0.490 0.510
E13 Other specified diabetes mellitus
0.001 0.492 0.507
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.493 0.507
M06.18 Adult-onset Still's disease (Other)
0.000 0.493 0.507
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.493 0.507
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.493 0.507
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.493 0.507
M06.14 Adult-onset Still's disease (Hand)
0.000 0.493 0.507
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.493 0.507
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.493 0.507
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.493 0.507
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.493 0.507
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.493 0.507
M06.28 Rheumatoid bursitis (Other)
0.000 0.493 0.507
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.493 0.507
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.493 0.507
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.493 0.507
M06.24 Rheumatoid bursitis (Hand)
0.000 0.493 0.507
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.493 0.507
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.493 0.507
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.493 0.507
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.493 0.507
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.493 0.507
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.493 0.507
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.493 0.507
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.493 0.507
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.493 0.507
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.493 0.507
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.493 0.507
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.493 0.507
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.493 0.507
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.493 0.507
H33 Retinal detachments and breaks
0.000 0.493 0.507
E61.9 Deficiency of nutrient element, unspecified
0.000 0.495 0.505
E61.8 Deficiency of other specified nutrient elements
0.000 0.495 0.505
E61.7 Deficiency of multiple nutrient elements
0.000 0.495 0.505
E61.6 Vanadium deficiency
0.000 0.495 0.505
E61.5 Molybdenum deficiency
0.000 0.495 0.505
E61.4 Chromium deficiency
0.000 0.495 0.505
E61.3 Manganese deficiency
0.000 0.495 0.505
E61.0 Copper deficiency
0.000 0.495 0.505
E73.8 Other lactose intolerance
0.000 0.497 0.503
E73.1 Secondary lactase deficiency
0.000 0.497 0.503
E73.0 Congenital lactase deficiency
0.000 0.497 0.503
J30-J39 Other diseases of upper respiratory tract
0.000 0.498 0.502
L40.0 Psoriasis vulgaris
0.000 0.505 0.495
E11.3 With ophthalmic complications
0.000 0.509 0.491
H33.3 Retinal breaks without detachment
0.000 0.509 0.491
J32 Chronic sinusitis
0.000 0.510 0.490
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.512 0.488
E70 Disorders of aromatic amino-acid metabolism
0.000 0.513 0.487
H33.2 Serous retinal detachment
0.000 0.515 0.485
J32.9 Chronic sinusitis, unspecified
0.000 0.520 0.480
E53.8 Deficiency of other specified B group vitamins
0.000 0.522 0.478
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.522 0.478
E45 Retarded development following protein-energy malnutrition
0.000 0.522 0.478
E43 Unspecified severe protein-energy malnutrition
0.000 0.522 0.478
E42 Marasmic kwashiorkor
0.000 0.522 0.478
E41 Nutritional marasmus
0.000 0.522 0.478
E40 Kwashiorkor
0.000 0.522 0.478
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.525 0.475
E04.1 Non-toxic single thyroid nodule
0.000 0.526 0.474
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.527 0.473
L40.3 Pustulosis palmaris et plantaris
0.000 0.533 0.467
L40.2 Acrodermatitis continua
0.000 0.533 0.467
M11 Other crystal arthropathies
0.000 0.535 0.465
E11.8 With unspecified complications
0.000 0.539 0.461
L40.1 Generalised pustular psoriasis
0.000 0.540 0.460
E89.4 Postprocedural ovarian failure
0.000 0.544 0.456
L40-L45 Papulosquamous disorders
0.000 0.546 0.454
J33.9 Nasal polyp, unspecified
0.000 0.547 0.453
G36.9 Acute disseminated demyelination, unspecified
0.000 0.548 0.452
G36.8 Other specified acute disseminated demyelination
0.000 0.548 0.452
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.548 0.452
G36.0 Neuromyelitis optica [Devic]
0.000 0.548 0.452
E50.9 Vitamin A deficiency, unspecified
0.000 0.549 0.451
E50.8 Other manifestations of vitamin A deficiency
0.000 0.549 0.451
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.549 0.451
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.549 0.451
E50.5 Vitamin A deficiency with night blindness
0.000 0.549 0.451
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.549 0.451
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.549 0.451
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.549 0.451
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.549 0.451
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.549 0.451
E56.9 Vitamin deficiency, unspecified
0.000 0.549 0.451
E56.8 Deficiency of other vitamins
0.000 0.549 0.451
E56.1 Deficiency of vitamin K
0.000 0.549 0.451
E56.0 Deficiency of vitamin E
0.000 0.549 0.451
E63.9 Nutritional deficiency, unspecified
0.000 0.549 0.451
E63.8 Other specified nutritional deficiencies
0.000 0.549 0.451
E63.1 Imbalance of constituents of food intake
0.000 0.549 0.451
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.549 0.451
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.549 0.451
E64.8 Sequelae of other nutritional deficiencies
0.000 0.549 0.451
E64.3 Sequelae of rickets
0.000 0.549 0.451
E64.2 Sequelae of vitamin C deficiency
0.000 0.549 0.451
E64.1 Sequelae of vitamin A deficiency
0.000 0.549 0.451
E64.0 Sequelae of protein-energy malnutrition
0.000 0.549 0.451
E88.8 Other specified metabolic disorders
0.000 0.550 0.450
J38.4 Oedema of larynx
0.000 0.551 0.449
J39 Other diseases of upper respiratory tract
0.000 0.552 0.448
K90 Intestinal malabsorption
0.000 0.553 0.446
J38.1 Polyp of vocal cord and larynx
0.000 0.555 0.445
E78.2 Mixed hyperlipidaemia
0.000 0.556 0.444
M07 Psoriatic and enteropathic arthropathies
0.000 0.559 0.440
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.561 0.439
E89.5 Postprocedural testicular hypofunction
0.000 0.561 0.439
E89.1 Postprocedural hypoinsulinaemia
0.000 0.561 0.439
E51.9 Thiamine deficiency, unspecified
0.000 0.563 0.436
E51.8 Other manifestations of thiamine deficiency
0.000 0.563 0.436
E51.1 Beriberi
0.000 0.563 0.436
E89.3 Postprocedural hypopituitarism
0.000 0.564 0.436
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.566 0.434
M08.9 Juvenile arthritis, unspecified
0.000 0.568 0.432
M08.8 Other juvenile arthritis
0.000 0.568 0.432
M08.4 Pauciarticular juvenile arthritis
0.000 0.568 0.432
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.568 0.432
M08.2 Juvenile arthritis with systemic onset
0.000 0.568 0.432
M08.1 Juvenile ankylosing spondylitis
0.000 0.568 0.432
M08.0 Juvenile rheumatoid arthritis
0.000 0.568 0.432
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.568 0.432
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.568 0.432
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.568 0.432
M09.0 Juvenile arthritis in psoriasis
0.000 0.568 0.432
E88.9 Metabolic disorder, unspecified
0.000 0.569 0.431
M05.09 Felty's syndrome (Site unspecified)
0.000 0.570 0.430
M05.08 Felty's syndrome (Other)
0.000 0.570 0.430
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.570 0.430
M05.06 Felty's syndrome (Lower leg)
0.000 0.570 0.430
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.570 0.430
M05.04 Felty's syndrome (Hand)
0.000 0.570 0.430
M05.03 Felty's syndrome (Forearm)
0.000 0.570 0.430
M05.02 Felty's syndrome (Upper arm)
0.000 0.570 0.430
M05.01 Felty's syndrome (Shoulder region)
0.000 0.570 0.430
M05.00 Felty's syndrome (Multiple sites)
0.000 0.570 0.430
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.570 0.430
M05.18 Rheumatoid lung disease (Other)
0.000 0.570 0.430
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.570 0.430
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.570 0.430
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.570 0.430
M05.14 Rheumatoid lung disease (Hand)
0.000 0.570 0.430
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.570 0.430
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.570 0.430
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.570 0.430
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.570 0.430
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.570 0.430
M05.28 Rheumatoid vasculitis (Other)
0.000 0.570 0.430
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.570 0.430
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.570 0.430
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.570 0.430
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.570 0.430
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.570 0.430
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.570 0.430
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.570 0.430
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.570 0.430
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.570 0.430
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.570 0.430
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.570 0.430
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.570 0.430
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.570 0.430
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.570 0.430
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.570 0.430
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.570 0.430
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.570 0.430
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.570 0.430
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.570 0.430
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.570 0.430
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.570 0.430
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.570 0.430
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.570 0.430
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.570 0.430
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.570 0.430
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.570 0.430
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.570 0.430
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.570 0.430
E83 Disorders of mineral metabolism
0.000 0.571 0.429
E61.2 Magnesium deficiency
0.000 0.573 0.427
E46 Unspecified protein-energy malnutrition
0.000 0.573 0.427
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.573 0.427
M13 Other arthritis
0.000 0.575 0.425
J32.8 Other chronic sinusitis
0.000 0.575 0.425
J38.0 Paralysis of vocal cords and larynx
0.000 0.575 0.425
M10.0 Idiopathic gout
0.000 0.581 0.419
E11.1 With ketoacidosis
0.000 0.582 0.418
H30 Chorioretinal inflammation
0.000 0.583 0.417
Chapter X Diseases of the respiratory system
0.000 0.584 0.416
E51.2 Wernicke's encephalopathy
0.000 0.584 0.416
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.584 0.416
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.584 0.416
M14.4 Arthropathy in amyloidosis
0.000 0.584 0.416
M14.3 Lipoid dermatoarthritis
0.000 0.584 0.416
M14.2 Diabetic arthropathy
0.000 0.584 0.416
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.584 0.416
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.584 0.416
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.584 0.415
M12.5 Traumatic arthropathy
0.000 0.584 0.415
M12.4 Intermittent hydrarthrosis
0.000 0.584 0.415
M12.3 Palindromic rheumatism
0.000 0.584 0.415
M12.1 Kaschin-Beck disease
0.000 0.584 0.415
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.584 0.415
J38.5 Laryngeal spasm
0.000 0.586 0.414
Chapter VI Diseases of the nervous system
0.000 0.587 0.413
E78.8 Other disorders of lipoprotein metabolism
0.000 0.589 0.411
E89.2 Postprocedural hypoparathyroidism
0.000 0.589 0.411
E11.0 With coma
0.000 0.592 0.408
# Top node
0.000 0.592 0.408
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.598 0.402
L40.8 Other psoriasis
0.000 0.598 0.402
E07.9 Disorder of thyroid, unspecified
0.000 0.598 0.401
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.600 0.400
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.601 0.398
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.601 0.398
E79.1 Lesch-Nyhan syndrome
0.000 0.601 0.398
E71.3 Disorders of fatty-acid metabolism
0.000 0.604 0.396
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.604 0.396
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.604 0.396
E71.0 Maple-syrup-urine disease
0.000 0.604 0.396
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.604 0.396
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.604 0.396
E72.5 Disorders of glycine metabolism
0.000 0.604 0.396
E72.4 Disorders of ornithine metabolism
0.000 0.604 0.396
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.604 0.396
E72.2 Disorders of urea cycle metabolism
0.000 0.604 0.396
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.604 0.396
E72.0 Disorders of amino-acid transport
0.000 0.604 0.396
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.604 0.396
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.604 0.396
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.604 0.396
E76.2 Other mucopolysaccharidoses
0.000 0.604 0.396
E76.1 Mucopolysaccharidosis, type II
0.000 0.604 0.396
E76.0 Mucopolysaccharidosis, type I
0.000 0.604 0.396
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.604 0.396
E77.8 Other disorders of glycoprotein metabolism
0.000 0.604 0.396
E77.1 Defects in glycoprotein degradation
0.000 0.604 0.396
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.604 0.396
E84.8 Cystic fibrosis with other manifestations
0.000 0.606 0.394
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.606 0.394
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.606 0.394
M14.6 Neuropathic arthropathy
0.000 0.608 0.392
M12.2 Villonodular synovitis (pigmented)
0.000 0.608 0.392
E84.9 Cystic fibrosis, unspecified
0.000 0.608 0.392
J20-J22 Other acute lower respiratory infections
0.000 0.609 0.391
Chapter VII Diseases of the eye and adnexa
0.000 0.610 0.390
L40.4 Guttate psoriasis
0.000 0.611 0.389
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.612 0.388
J32.0 Chronic maxillary sinusitis
0.000 0.612 0.388
E83.1 Disorders of iron metabolism
0.000 0.612 0.388
J32.4 Chronic pansinusitis
0.000 0.613 0.387
J33.1 Polypoid sinus degeneration
0.000 0.613 0.387
J39.8 Other specified diseases of upper respiratory tract
0.000 0.614 0.386
M10.4 Other secondary gout
0.000 0.616 0.384
M10.3 Gout due to impairment of renal function
0.000 0.616 0.384
M10.2 Drug-induced gout
0.000 0.616 0.384
M10.1 Lead-induced gout
0.000 0.616 0.384
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.616 0.384
E11.7 With multiple complications
0.000 0.619 0.381
E88.3 Tumour lysis syndrome
0.000 0.620 0.380
H33.4 Traction detachment of retina
0.000 0.623 0.377
H34 Retinal vascular occlusions
0.000 0.625 0.375
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.627 0.373
E88.2 Lipomatosis, not elsewhere classified
0.000 0.628 0.372
B37.8 Candidiasis of other sites
0.000 0.629 0.371
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.629 0.370
Chapter I Certain infectious and parasitic diseases
0.000 0.630 0.370
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.632 0.368
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.632 0.368
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.632 0.368
E74.2 Disorders of galactose metabolism
0.000 0.632 0.368
E74.1 Disorders of fructose metabolism
0.000 0.632 0.368
E74.0 Glycogen storage disease
0.000 0.632 0.368
J38.2 Nodules of vocal cords
0.000 0.633 0.367
E13.8 With unspecified complications
0.001 0.636 0.364
E13.7 With multiple complications
0.001 0.636 0.364
E13.6 With other specified complications
0.001 0.636 0.364
E13.5 With peripheral circulatory complications
0.001 0.636 0.364
E13.4 With neurological complications
0.001 0.636 0.364
E13.3 With ophthalmic complications
0.001 0.636 0.364
E13.2 With renal complications
0.001 0.636 0.364

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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