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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4409766
log Bayes Factor = 8.10428
Chromosome 10   position 104,616,663  (GRCh37) Explore rs4409766 on Ensembl!
Variant rs4409766 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.012 0.988
I10 Essential (primary) hypertension
0.000 0.013 0.987
I25.1 Atherosclerotic heart disease
0.000 0.020 0.980
I25.2 Old myocardial infarction
0.000 0.022 0.978
I24 Other acute ischaemic heart diseases
0.000 0.022 0.978
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.022 0.978
I21 Acute myocardial infarction
0.000 0.056 0.944
I10-I15 Hypertensive diseases
0.000 0.056 0.944
Chapter IX Diseases of the circulatory system
0.000 0.078 0.922
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.081 0.919
I21.4 Acute subendocardial myocardial infarction
0.000 0.094 0.906
I22 Subsequent myocardial infarction
0.000 0.103 0.897
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.108 0.892
I24.8 Other forms of acute ischaemic heart disease
0.000 0.113 0.887
I60-I69 Cerebrovascular diseases
0.000 0.152 0.848
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.155 0.845
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.176 0.824
I69 Sequelae of cerebrovascular disease
0.000 0.193 0.807
I20.1 Angina pectoris with documented spasm
0.000 0.201 0.799
I15 Secondary hypertension
0.000 0.218 0.781
I25.4 Coronary artery aneurysm
0.000 0.219 0.781
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.241 0.759
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.261 0.739
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.277 0.723
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.278 0.722
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.282 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I25.3 Aneurysm of heart
0.000 0.292 0.708
I24.1 Dressler's syndrome
0.000 0.299 0.701
I25.5 Ischaemic cardiomyopathy
0.000 0.299 0.701
I22.8 Subsequent myocardial infarction of other sites
0.000 0.305 0.695
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.323 0.677
I13 Hypertensive heart and renal disease
0.000 0.323 0.677
I69.3 Sequelae of cerebral infarction
0.000 0.326 0.674
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.329 0.671
I15.1 Hypertension secondary to other renal disorders
0.000 0.335 0.665
I00-I02 Acute rheumatic fever
0.000 0.339 0.661
I62 Other nontraumatic intracranial haemorrhage
0.000 0.346 0.654
I23 Certain current complications following acute myocardial infarction
0.000 0.346 0.653
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.347 0.653
I65.2 Occlusion and stenosis of carotid artery
0.000 0.348 0.652
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.352 0.648
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.357 0.643
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.364 0.636
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.392 0.608
I11 Hypertensive heart disease
0.000 0.404 0.596
I63 Cerebral infarction
0.000 0.405 0.595
I60 Subarachnoid haemorrhage
0.000 0.415 0.585
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.421 0.579
I15.9 Seconday hypertension, unspecified
0.000 0.440 0.560
I15.8 Other secondary hypertension
0.000 0.440 0.560
I15.2 Hypertension secondary to endocrine disorders
0.000 0.440 0.560
I15.0 Renovascular hypertension
0.000 0.440 0.560
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.443 0.557
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.459 0.541
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.482 0.517
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.482 0.517
I65.1 Occlusion and stenosis of basilar artery
0.000 0.482 0.517
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.482 0.517
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.486 0.514
I67 Other cerebrovascular diseases
0.000 0.487 0.513
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.505 0.495
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.507 0.493
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.514 0.486
I21.9 Acute myocardial infarction, unspecified
0.000 0.514 0.486
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.515 0.485
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.515 0.485
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.515 0.485
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.515 0.485
I12 Hypertensive renal disease
0.000 0.516 0.484
I02 Rheumatic chorea
0.000 0.526 0.474
I01 Rheumatic fever with heart involvement
0.000 0.526 0.474
I00 Rheumatic fever without mention of heart involvement
0.000 0.526 0.474
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.528 0.472
I62.1 Nontraumatic extradural haemorrhage
0.000 0.531 0.469
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.531 0.468
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.531 0.468
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.531 0.468
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.531 0.468
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.531 0.468
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.531 0.468
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.531 0.468
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.534 0.466
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.536 0.464
I60.8 Other subarachnoid haemorrhage
0.000 0.541 0.459
I67.1 Cerebral aneurysm, nonruptured
0.000 0.541 0.459
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.542 0.457
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.547 0.453
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.547 0.453
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.564 0.436
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.564 0.436
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.564 0.436
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.564 0.436
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.564 0.436
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.564 0.436
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.564 0.436
I63.8 Other cerebral infarction
0.000 0.568 0.432
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.574 0.426
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.574 0.426
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.574 0.426
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.580 0.420
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.580 0.420
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.580 0.420
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.580 0.420
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.580 0.420
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.591 0.409
I23.8 Other current complications following acute myocardial infarction
0.000 0.595 0.405
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.612 0.388
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.612 0.388
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.612 0.388
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.612 0.388
I67.2 Cerebral atherosclerosis
0.000 0.622 0.378
I99 Other and unspecified disorders of circulatory system
0.000 0.623 0.377
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.626 0.374
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.628 0.372
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.632 0.368
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.632 0.368
I67.5 Moyamoya disease
0.000 0.632 0.368
I67.4 Hypertensive encephalopathy
0.000 0.632 0.368
I67.3 Progressive vascular leukoencephalopathy
0.000 0.632 0.368
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.632 0.368
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.643 0.357
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.660 0.340
I01.8 Other acute rheumatic heart disease
0.000 0.660 0.340
I01.2 Acute rheumatic myocarditis
0.000 0.660 0.340
I01.1 Acute rheumatic endocarditis
0.000 0.660 0.340
I01.0 Acute rheumatic pericarditis
0.000 0.660 0.340
I02.9 Rheumatic chorea without heart involvement
0.000 0.660 0.340
I02.0 Rheumatic chorea with heart involvement
0.000 0.660 0.340
I12.9 Hypertensive renal disease without renal failure
0.000 0.665 0.335
I68.0 Cerebral amyloid angiopathy
0.001 0.679 0.320
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.714 0.286
I05-I09 Chronic rheumatic heart diseases
0.000 0.715 0.284
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.719 0.281
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.724 0.276
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.726 0.274
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.726 0.274
I20.8 Other forms of angina pectoris
0.000 0.736 0.263
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.744 0.256
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.744 0.256
I98.0 Cardiovascular syphilis
0.000 0.744 0.256
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.755 0.245
I77 Other disorders of arteries and arterioles
0.000 0.762 0.238
I67.8 Other specified cerebrovascular diseases
0.000 0.772 0.228
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.781 0.219
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.781 0.219
I77.1 Stricture of artery
0.000 0.782 0.218
I09 Other rheumatic heart diseases
0.000 0.796 0.204
I06 Rheumatic aortic valve diseases
0.000 0.796 0.204
I71 Aortic aneurysm and dissection
0.000 0.798 0.202
I97.9 Postprocedural disorder of circulatory system, unspecified
0.001 0.803 0.196
I97.0 Postcardiotomy syndrome
0.001 0.803 0.196
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.808 0.192
I07 Rheumatic tricuspid valve diseases
0.000 0.810 0.190
I12.0 Hypertensive renal disease with renal failure
0.000 0.820 0.180
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.822 0.178
I70 Atherosclerosis
0.000 0.823 0.177
I77.6 Arteritis, unspecified
0.000 0.823 0.177
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.826 0.174
I28 Other diseases of pulmonary vessels
0.001 0.828 0.171
I78 Diseases of capillaries
0.000 0.829 0.171
I77.5 Necrosis of artery
0.000 0.829 0.171
I77.4 Coeliac artery compression syndrome
0.000 0.829 0.171
I77.3 Arterial fibromuscular dysplasia
0.000 0.829 0.171
I77.2 Rupture of artery
0.000 0.829 0.171
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.833 0.167
I71.0 Dissection of aorta [any part]
0.000 0.834 0.166
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.836 0.164
I61 Intracerebral haemorrhage
0.003 0.838 0.160
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.841 0.158
I77.8 Other specified disorders of arteries and arterioles
0.000 0.841 0.159
I67.9 Cerebrovascular disease, unspecified
0.000 0.841 0.158
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.843 0.157
I79.1 Aortitis in diseases classified elsewhere
0.000 0.843 0.157
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.843 0.157
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.844 0.156
I77.0 Arteriovenous fistula, acquired
0.000 0.847 0.153
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.847 0.153
Z95.2 Presence of prosthetic heart valve
0.000 0.851 0.149
I05 Rheumatic mitral valve diseases
0.001 0.852 0.147
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.853 0.146
I06.8 Other rheumatic aortic valve diseases
0.000 0.853 0.146
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.853 0.146
I06.1 Rheumatic aortic insufficiency
0.000 0.853 0.146
I06.0 Rheumatic aortic stenosis
0.000 0.853 0.146
I09.9 Rheumatic heart disease, unspecified
0.000 0.853 0.146
I09.8 Other specified rheumatic heart diseases
0.000 0.853 0.146
I09.2 Chronic rheumatic pericarditis
0.000 0.853 0.146
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.853 0.146
I09.0 Rheumatic myocarditis
0.000 0.853 0.146
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.855 0.145
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.855 0.145
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.855 0.145
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.855 0.145
I97.1 Other functional disturbances following cardiac surgery
0.001 0.856 0.143
I74 Arterial embolism and thrombosis
0.000 0.861 0.139
I07.9 Tricuspid valve disease, unspecified
0.000 0.864 0.136
I07.8 Other tricuspid valve diseases
0.000 0.864 0.136
I07.2 Tricuspid stenosis with insufficiency
0.000 0.864 0.136
I07.0 Tricuspid stenosis
0.000 0.864 0.136
Z95.3 Presence of xenogenic heart valve
0.000 0.868 0.132
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.870 0.130
I70.9 Generalised and unspecified atherosclerosis
0.000 0.872 0.127
I70.8 Atherosclerosis of other arteries
0.000 0.872 0.127
I27 Other pulmonary heart diseases
0.001 0.873 0.127
I70.1 Atherosclerosis of renal artery
0.000 0.875 0.125
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.877 0.123
I28.1 Aneurysm of pulmonary artery
0.001 0.877 0.123
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.877 0.123
I78.9 Disease of capillaries, unspecified
0.000 0.877 0.123
I07.1 Tricuspid insufficiency
0.000 0.878 0.122
I70.0 Atherosclerosis of aorta
0.000 0.878 0.121
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.878 0.121
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.880 0.120
I61.5 Intracerebral haemorrhage, intraventricular
0.002 0.880 0.118
I78.8 Other diseases of capillaries
0.000 0.882 0.118
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.002 0.882 0.116
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.883 0.117
I61.6 Intracerebral haemorrhage, multiple localised
0.002 0.883 0.115
I72 Other aneurysm
0.000 0.886 0.113
I05.1 Rheumatic mitral insufficiency
0.000 0.887 0.113
Z95.4 Presence of other heart-valve replacement
0.000 0.888 0.112
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.002 0.889 0.108
I61.3 Intracerebral haemorrhage in brain stem
0.002 0.890 0.108
I74.5 Embolism and thrombosis of iliac artery
0.000 0.892 0.107
Z95.0 Presence of cardiac pacemaker
0.000 0.893 0.107
I05.8 Other mitral valve diseases
0.001 0.894 0.106
I78.1 Naevus, nonneoplastic
0.000 0.895 0.105
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.896 0.104
I61.8 Other intracerebral haemorrhage
0.002 0.897 0.100
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.900 0.100
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.900 0.100
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.900 0.100
I28.8 Other specified diseases of pulmonary vessels
0.001 0.902 0.097
I74.8 Embolism and thrombosis of other arteries
0.000 0.903 0.097
I05.9 Mitral valve disease, unspecified
0.000 0.904 0.096
I61.4 Intracerebral haemorrhage in cerebellum
0.003 0.905 0.093
I27.0 Primary pulmonary hypertension
0.000 0.906 0.094
I27.8 Other specified pulmonary heart diseases
0.000 0.906 0.094
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.908 0.091
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.908 0.091
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.908 0.091
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.908 0.091
I72.0 Aneurysm of carotid artery
0.000 0.908 0.091
I27.1 Kyphoscoliotic heart disease
0.001 0.909 0.091
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.910 0.090
I26 Pulmonary embolism
0.001 0.910 0.089
I05.2 Mitral stenosis with insufficiency
0.001 0.911 0.089
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.912 0.088
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.912 0.088
I63.9 Cerebral infarction, unspecified
0.000 0.912 0.088
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.913 0.087
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.916 0.084
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.003 0.917 0.081
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.917 0.082
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.918 0.081
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.918 0.081
I72.1 Aneurysm of artery of upper extremity
0.000 0.918 0.081
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.919 0.081
I05.0 Mitral stenosis
0.001 0.919 0.081
I72.8 Aneurysm of other specified arteries
0.000 0.921 0.079
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.923 0.077
I72.2 Aneurysm of renal artery
0.000 0.924 0.076
I27.9 Pulmonary heart disease, unspecified
0.001 0.924 0.075
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.926 0.073
I72.9 Aneurysm of unspecified site
0.000 0.929 0.070
I95 Hypotension
0.001 0.936 0.062
R07.4 Chest pain, unspecified
0.000 0.940 0.060
I72.4 Aneurysm of artery of lower extremity
0.001 0.941 0.058
I72.3 Aneurysm of iliac artery
0.001 0.944 0.055
I08 Multiple valve diseases
0.001 0.944 0.055
Z95.1 Presence of aortocoronary bypass graft
0.000 0.945 0.055
I73 Other peripheral vascular diseases
0.000 0.946 0.054
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.949 0.051
I95.8 Other hypotension
0.001 0.954 0.045
I95.0 Idiopathic hypotension
0.001 0.954 0.045
I08.2 Disorders of both aortic and tricuspid valves
0.001 0.957 0.042
I30-I52 Other forms of heart disease
0.000 0.957 0.043
I08.9 Multiple valve disease, unspecified
0.001 0.960 0.040
I27.2 Other secondary pulmonary hypertension
0.001 0.960 0.039
I44 Atrioventricular and left bundle-branch block
0.000 0.960 0.040
I61.9 Intracerebral haemorrhage, unspecified
0.003 0.960 0.036
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.961 0.039
I45 Other conduction disorders
0.000 0.962 0.038
I50 Heart failure
0.000 0.962 0.038
I73.8 Other specified peripheral vascular diseases
0.000 0.963 0.037
I44.1 Atrioventricular block, second degree
0.000 0.963 0.037
I44.7 Left bundle-branch block, unspecified
0.000 0.963 0.037
I50.1 Left ventricular failure
0.000 0.964 0.036
I45.1 Other and unspecified right bundle-branch block
0.000 0.965 0.035
I08.8 Other multiple valve diseases
0.001 0.966 0.034
I95.2 Hypotension due to drugs
0.001 0.966 0.033
I44.0 Atrioventricular block, first degree
0.000 0.968 0.032
I45.6 Preexcitation syndrome
0.000 0.968 0.031
I45.2 Bifascicular block
0.000 0.969 0.031
I46 Cardiac arrest
0.000 0.969 0.031
I52 Other heart disorders in diseases classified elsewhere
0.000 0.969 0.031
I48 Atrial fibrillation and flutter
0.000 0.969 0.031
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.969 0.031
I41 Myocarditis in diseases classified elsewhere
0.000 0.969 0.031
I40 Acute myocarditis
0.000 0.969 0.031
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.969 0.031
I32 Pericarditis in diseases classified elsewhere
0.000 0.969 0.031
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.969 0.030
I44.6 Other and unspecified fascicular block
0.000 0.970 0.030
I36 Nonrheumatic tricuspid valve disorders
0.000 0.970 0.030
I37 Pulmonary valve disorders
0.000 0.971 0.029
I44.5 Left posterior fascicular block
0.000 0.971 0.029
I33 Acute and subacute endocarditis
0.000 0.971 0.029
I45.3 Trifascicular block
0.000 0.971 0.029
I45.0 Right fascicular block
0.000 0.972 0.028
I45.4 Nonspecific intraventricular block
0.000 0.972 0.027
I45.8 Other specified conduction disorders
0.000 0.973 0.027
I50.0 Congestive heart failure
0.000 0.973 0.027
I44.3 Other and unspecified atrioventricular block
0.000 0.974 0.026
I45.5 Other specified heart block
0.000 0.975 0.025
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.001 0.975 0.024
I46.0 Cardiac arrest with successful resuscitation
0.000 0.975 0.025
R07 Pain in throat and chest
0.000 0.976 0.024
I35 Nonrheumatic aortic valve disorders
0.000 0.976 0.024
I30 Acute pericarditis
0.000 0.977 0.023
I31 Other diseases of pericardium
0.000 0.977 0.023
I46.1 Sudden cardiac death, so described
0.000 0.977 0.022
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.978 0.022
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.978 0.022
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.978 0.022
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.978 0.022
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.978 0.022
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.978 0.022
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.978 0.022
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.978 0.022
I40.9 Acute myocarditis, unspecified
0.000 0.978 0.022
I40.8 Other acute myocarditis
0.000 0.978 0.022
I40.1 Isolated myocarditis
0.000 0.978 0.022
I40.0 Infective myocarditis
0.000 0.978 0.022
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.978 0.022
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.978 0.022
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.978 0.022
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.978 0.022
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.978 0.022
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.978 0.022
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.978 0.022
I48.4 Atypical atrial flutter
0.000 0.978 0.022
I48.3 Typical atrial flutter
0.000 0.978 0.022
I48.2 Chronic atrial fibrillation
0.000 0.978 0.022
I48.1 Persistent atrial fibrillation
0.000 0.978 0.022
I48.0 Paroxysmal atrial fibrillation
0.000 0.978 0.022
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.978 0.022
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.978 0.022
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.978 0.022
I45.9 Conduction disorder, unspecified
0.000 0.978 0.022
I44.4 Left anterior fascicular block
0.000 0.978 0.022
I50.9 Heart failure, unspecified
0.000 0.978 0.022
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.978 0.021
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.978 0.021
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.978 0.021
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.978 0.021
R07.2 Precordial pain
0.000 0.979 0.021
I38 Endocarditis, valve unspecified
0.000 0.979 0.021
I37.9 Pulmonary valve disorder, unspecified
0.000 0.979 0.021
I37.8 Other pulmonary valve disorders
0.000 0.979 0.021
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.979 0.021
I37.0 Pulmonary valve stenosis
0.000 0.979 0.021
I33.9 Acute endocarditis, unspecified
0.000 0.979 0.021
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.980 0.020
I46.9 Cardiac arrest, unspecified
0.000 0.980 0.020
I44.2 Atrioventricular block, complete
0.000 0.980 0.020
R07.0 Pain in throat
0.000 0.980 0.020
I35.9 Aortic valve disorder, unspecified
0.000 0.981 0.019
I42 Cardiomyopathy
0.000 0.981 0.019
I37.1 Pulmonary valve insufficiency
0.000 0.981 0.019
I49 Other cardiac arrhythmias
0.000 0.981 0.019
I33.0 Acute and subacute infective endocarditis
0.000 0.981 0.019
I49.0 Ventricular fibrillation and flutter
0.000 0.982 0.018
I35.1 Aortic (valve) insufficiency
0.000 0.983 0.017
G40.9 Epilepsy, unspecified
0.000 0.983 0.017
I30.8 Other forms of acute pericarditis
0.000 0.983 0.017
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.983 0.017
I31.8 Other specified diseases of pericardium
0.000 0.983 0.017
I31.2 Haemopericardium, not elsewhere classified
0.000 0.983 0.017
I31.1 Chronic constrictive pericarditis
0.000 0.983 0.017
I31.0 Chronic adhesive pericarditis
0.000 0.983 0.017
I35.0 Aortic (valve) stenosis
0.000 0.984 0.016
G40 Epilepsy
0.000 0.984 0.016
I42.6 Alcoholic cardiomyopathy
0.000 0.984 0.015
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.985 0.015
I42.0 Dilated cardiomyopathy
0.000 0.985 0.015
I30.1 Infective pericarditis
0.000 0.985 0.014
I31.3 Pericardial effusion (noninflammatory)
0.000 0.986 0.014
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.986 0.014
I42.5 Other restrictive cardiomyopathy
0.000 0.986 0.014
I42.4 Endocardial fibroelastosis
0.000 0.986 0.014
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.986 0.014
I49.2 Junctional premature depolarisation
0.000 0.986 0.014
I35.8 Other aortic valve disorders
0.000 0.986 0.014
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.986 0.014
I95.1 Orthostatic hypotension
0.001 0.987 0.013
I49.1 Atrial premature depolarisation
0.000 0.987 0.013
I31.9 Disease of pericardium, unspecified
0.000 0.987 0.013
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.987 0.013
I30.9 Acute pericarditis, unspecified
0.000 0.987 0.012
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.012 0.988 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.988 0.012
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.988 0.012
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.988 0.012
I08.0 Disorders of both mitral and aortic valves
0.001 0.988 0.011
R22.4 Localised swelling, mass and lump, lower limb
0.012 0.988 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.988 0.012
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.012 0.988 0.000
G40.8 Other epilepsy
0.000 0.988 0.012
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.988 0.012
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.988 0.012
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.988 0.012
R22.1 Localised swelling, mass and lump, neck
0.012 0.988 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.988 0.011
I49.9 Cardiac arrhythmia, unspecified
0.000 0.989 0.011
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.011 0.989 0.000
I49.8 Other specified cardiac arrhythmias
0.000 0.989 0.011
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.011 0.989 0.000
G40.5 Special epileptic syndromes
0.000 0.989 0.011
I49.4 Other and unspecified premature depolarisation
0.000 0.989 0.011
I47 Paroxysmal tachycardia
0.000 0.989 0.011
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.011 0.989 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.011 0.989 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.010 0.990 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.010 0.990 0.000
I49.5 Sick sinus syndrome
0.000 0.990 0.010
R22.0 Localised swelling, mass and lump, head
0.010 0.990 0.000
K30 Dyspepsia
0.000 0.990 0.010
R07.3 Other chest pain
0.000 0.990 0.010
R07.1 Chest pain on breathing
0.000 0.990 0.010
I42.8 Other cardiomyopathies
0.000 0.990 0.010
M25.46 Effusion of joint (Lower leg)
0.010 0.990 0.000
K62.0 Anal polyp
0.010 0.990 0.000
R22.2 Localised swelling, mass and lump, trunk
0.009 0.991 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.009 0.991 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.009 0.991 0.000
I42.9 Cardiomyopathy, unspecified
0.000 0.991 0.009
I87 Other disorders of veins
0.000 0.991 0.008
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.009 0.991 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.009 0.991 0.000
I73.0 Raynaud's syndrome
0.000 0.991 0.008
M65.4 Radial styloid tenosynovitis [de Quervain]
0.008 0.992 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.008 0.992 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.008 0.992 0.000
I88 Nonspecific lymphadenitis
0.000 0.992 0.008
R22.7 Localised swelling, mass and lump, multiple sites
0.008 0.992 0.000
C20 Malignant neoplasm of rectum
0.008 0.992 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.008 0.992 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.008 0.992 0.000
G40-G47 Episodic and paroxysmal disorders
0.000 0.992 0.008
I49.3 Ventricular premature depolarisation
0.000 0.992 0.008
M65 Synovitis and tenosynovitis
0.008 0.992 0.000
M07.3 Other psoriatic arthropathies
0.008 0.992 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.008 0.992 0.000
G45.3 Amaurosis fugax
0.000 0.992 0.008
I87.1 Compression of vein
0.000 0.992 0.007
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.007 0.993 0.000
I82 Other venous embolism and thrombosis
0.000 0.993 0.007
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.993 0.007
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.007 0.993 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.007 0.993 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.993 0.007
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.993 0.007
F31.9 Bipolar affective disorder, unspecified
0.000 0.993 0.007
M07.34 Other psoriatic arthropathies (Hand)
0.007 0.993 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.993 0.007
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.993 0.007
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.000 0.993 0.007
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.007 0.993 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.007 0.993 0.000
I81 Portal vein thrombosis
0.000 0.993 0.007
I73.9 Peripheral vascular disease, unspecified
0.000 0.993 0.007
R22.3 Localised swelling, mass and lump, upper limb
0.007 0.993 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.007 0.993 0.000
F31 Bipolar affective disorder
0.000 0.993 0.007
I86 Varicose veins of other sites
0.000 0.993 0.007
M07.30 Other psoriatic arthropathies (Multiple sites)
0.007 0.993 0.000
I87.9 Disorder of vein, unspecified
0.000 0.993 0.006
I87.0 Postphlebitic syndrome
0.000 0.993 0.006
I89.1 Lymphangitis
0.000 0.994 0.006
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.006 0.994 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.006 0.994 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.006 0.994 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.006 0.994 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.006 0.994 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.006 0.994 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.006 0.994 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.006 0.994 0.000
R63.4 Abnormal weight loss
0.000 0.994 0.006
I88.8 Other nonspecific lymphadenitis
0.000 0.994 0.006
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.994 0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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