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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs443198
log Bayes Factor = 204.432
Chromosome 6   position 32,190,406  (GRCh37) Explore rs443198 on Ensembl!
Variant rs443198 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
L40 Psoriasis
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.998 0.002 0.000
E10.9 Without complications
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.997 0.003 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.006 0.994
E11 Non-insulin-dependent diabetes mellitus
0.993 0.007 0.000
E05.9 Thyrotoxicosis, unspecified
0.993 0.007 0.000
E14 Unspecified diabetes mellitus
0.992 0.008 0.000
C21 Malignant neoplasm of anus and anal canal
0.990 0.010 0.000
E11.9 Without complications
0.986 0.014 0.000
D64.9 Anaemia, unspecified
0.984 0.016 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.981 0.019 0.000
Chapter II Neoplasms
0.980 0.020 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.980 0.020 0.000
C18 Malignant neoplasm of colon
0.979 0.021 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.978 0.022 0.000
C85.1 B-cell lymphoma, unspecified
0.978 0.022 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.976 0.024 0.000
G35 Multiple sclerosis
0.000 0.027 0.973
E10.1 With ketoacidosis
0.970 0.030 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.969 0.031 0.000
L40.0 Psoriasis vulgaris
0.967 0.033 0.000
C18.6 Descending colon
0.964 0.036 0.000
E16 Other disorders of pancreatic internal secretion
0.963 0.037 0.000
C15 Malignant neoplasm of oesophagus
0.962 0.038 0.000
E10.3 With ophthalmic complications
0.956 0.044 0.000
L40.5 Arthropathic psoriasis
0.956 0.044 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.953 0.047 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.951 0.049 0.000
C21.0 Anus, unspecified
0.950 0.050 0.000
C21.1 Anal canal
0.947 0.053 0.000
C15.4 Middle third of oesophagus
0.939 0.061 0.000
E14.3 With ophthalmic complications
0.939 0.061 0.000
E16.2 Hypoglycaemia, unspecified
0.938 0.062 0.000
C18.7 Sigmoid colon
0.937 0.063 0.000
E11.1 With ketoacidosis
0.930 0.070 0.000
D00-D09 In situ neoplasms
0.923 0.077 0.000
L40-L45 Papulosquamous disorders
0.921 0.079 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.919 0.081 0.000
C23 Malignant neoplasm of gallbladder
0.918 0.082 0.000
C22.9 Liver, unspecified
0.916 0.084 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.903 0.097 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.902 0.098 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.900 0.100 0.000
C18.9 Colon, unspecified
0.896 0.104 0.000
E13 Other specified diabetes mellitus
0.890 0.110 0.000
D07.1 Vulva
0.884 0.116 0.000
C22.0 Liver cell carcinoma
0.883 0.117 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.883 0.117 0.000
E14.1 With ketoacidosis
0.874 0.126 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.871 0.129 0.000
C02.9 Tongue, unspecified
0.870 0.130 0.000
D64 Other anaemias
0.868 0.132 0.000
E14.9 Without complications
0.864 0.136 0.000
C18.1 Appendix
0.862 0.138 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.855 0.145 0.000
C04 Malignant neoplasm of floor of mouth
0.855 0.145 0.000
M45 Ankylosing spondylitis
0.000 0.149 0.850
J45.9 Asthma, unspecified
0.848 0.152 0.000
E14.8 With unspecified complications
0.841 0.159 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.166 0.834
E03.8 Other specified hypothyroidism
0.832 0.168 0.000
D07.4 Penis
0.830 0.170 0.000
C32 Malignant neoplasm of larynx
0.829 0.171 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.827 0.173 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.826 0.173 0.000
# Top node
0.823 0.177 0.000
E13.9 Without complications
0.819 0.181 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
E11.2 With renal complications
0.817 0.183 0.000
C02.1 Border of tongue
0.813 0.187 0.000
C83.3 Large cell (diffuse)
0.811 0.189 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.808 0.192 0.000
E10.8 With unspecified complications
0.808 0.192 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.807 0.193 0.000
L40.1 Generalised pustular psoriasis
0.805 0.195 0.000
C95 Leukaemia of unspecified cell type
0.803 0.197 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.198 0.802
Q50-Q56 Congenital malformations of genital organs
0.800 0.200 0.000
D60-D64 Aplastic and other anaemias
0.799 0.201 0.000
L40.3 Pustulosis palmaris et plantaris
0.794 0.206 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.793 0.207 0.000
L50-L54 Urticaria and erythema
0.792 0.208 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.791 0.209 0.000
E16.1 Other hypoglycaemia
0.790 0.210 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.790 0.210 0.000
C32.0 Glottis
0.790 0.210 0.000
E14.4 With neurological complications
0.785 0.215 0.000
C45 Mesothelioma
0.782 0.218 0.000
C04.9 Floor of mouth, unspecified
0.781 0.219 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.781 0.219 0.000
E11.0 With coma
0.780 0.220 0.000
C22.1 Intrahepatic bile duct carcinoma
0.776 0.224 0.000
L44 Other papulosquamous disorders
0.775 0.225 0.000
E03.1 Congenital hypothyroidism without goitre
0.773 0.227 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.765 0.235 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.235 0.765
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.236 0.764
C15.3 Upper third of oesophagus
0.763 0.237 0.000
C91 Lymphoid leukaemia
0.762 0.238 0.000
L52 Erythema nodosum
0.761 0.239 0.000
C82.0 Small cleaved cell, follicular
0.761 0.239 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.760 0.240 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.240 0.760
C84.8 Cutaneous T-cell lymphoma, unspecified
0.758 0.242 0.000
C82.2 Large cell, follicular
0.758 0.242 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.756 0.244 0.000
D09 Carcinoma in situ of other and unspecified sites
0.754 0.246 0.000
C60-C63 Malignant neoplasms of male genital organs
0.749 0.246 0.006
Q54 Hypospadias
0.754 0.246 0.000
K90 Intestinal malabsorption
0.753 0.247 0.000
C07 Malignant neoplasm of parotid gland
0.750 0.250 0.000
C15.1 Thoracic part of oesophagus
0.749 0.251 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.746 0.254 0.000
E10.2 With renal complications
0.746 0.254 0.000
C15.0 Cervical part of oesophagus
0.745 0.255 0.000
E10.0 With coma
0.743 0.257 0.000
C32.9 Larynx, unspecified
0.741 0.259 0.000
E14.0 With coma
0.737 0.263 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.734 0.266 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.733 0.267 0.000
L10-L14 Bullous disorders
0.730 0.270 0.000
E10.7 With multiple complications
0.727 0.273 0.000
C03 Malignant neoplasm of gum
0.724 0.276 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.721 0.279 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.718 0.282 0.000
E14.2 Withrenal complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.716 0.283 0.000
C17 Malignant neoplasm of small intestine
0.716 0.284 0.000
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.716 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.284 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.716 0.284 0.000
E10.6 With other specified complications
0.715 0.285 0.000
C12 Malignant neoplasm of pyriform sinus
0.715 0.285 0.000
C13 Malignant neoplasm of hypopharynx
0.715 0.285 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.713 0.287 0.000
E11.7 With multiple complications
0.712 0.288 0.000
E14.7 With multiple complications
0.711 0.288 0.000
C82.3 Follicular lymphoma grade IIIa
0.711 0.289 0.000
C21.2 Cloacogenic zone
0.710 0.290 0.000
C95.9 Leukaemia, unspecified
0.707 0.293 0.000
E14.5 With peripheral circulatory complications
0.706 0.294 0.000
L43 Lichen planus
0.705 0.295 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.704 0.296 0.000
E20-E35 Disorders of other endocrine glands
0.704 0.296 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.704 0.296 0.000
C94 Other leukaemias of specified cell type
0.704 0.296 0.000
C85.0 Lymphosarcoma
0.702 0.297 0.000
E15 Nondiabetic hypoglycaemic coma
0.701 0.299 0.000
L13 Other bullous disorders
0.701 0.299 0.000
C22.7 Other specified carcinomas of liver
0.700 0.300 0.000
C22.4 Other sarcomas of liver
0.700 0.300 0.000
C22.3 Angiosarcoma of liver
0.700 0.300 0.000
C22.2 Hepatoblastoma
0.700 0.300 0.000
C45.9 Mesothelioma, unspecified
0.700 0.300 0.000
E40-E46 Malnutrition
0.699 0.301 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.697 0.303 0.000
E11.5 With peripheral circulatory complications
0.695 0.305 0.000
Q00-Q07 Congenital malformations of the nervous system
0.691 0.308 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.691 0.309 0.000
C45.0 Mesothelioma of pleura
0.691 0.309 0.000
C86 Other specified types of T/NK-cell lymphoma
0.691 0.309 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.690 0.310 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.690 0.310 0.000
E16.4 Abnormal secretion of gastrin
0.690 0.310 0.000
E16.3 Increased secretion of glucagon
0.690 0.310 0.000
E11.8 With unspecified complications
0.690 0.310 0.000
C15.8 Overlapping lesion of oesophagus
0.690 0.310 0.000
C15.2 Abdominal part of oesophagus
0.690 0.310 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.311 0.689
C82.4 Follicular lymphoma grade IIIb
0.686 0.314 0.000
C82.6 Cutaneous follicle centre lymphoma
0.683 0.317 0.000
C82.5 Diffuse follicle centre lymphoma
0.683 0.317 0.000
L50 Urticaria
0.682 0.318 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.682 0.318 0.000
Q54.1 Hypospadias, penile
0.681 0.319 0.000
L13.0 Dermatitis herpetiformis
0.680 0.320 0.000
Q51 Congenital malformations of uterus and cervix
0.679 0.321 0.000
D01.3 Anus and anal canal
0.677 0.323 0.000
C11 Malignant neoplasm of nasopharynx
0.672 0.328 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.672 0.328 0.000
L44.0 Pityriasis rubra pilaris
0.671 0.329 0.000
Q43 Other congenital malformations of intestine
0.669 0.331 0.000
K90.9 Intestinal malabsorption, unspecified
0.669 0.331 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.668 0.332 0.000
C09 Malignant neoplasm of tonsil
0.668 0.332 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.665 0.335 0.000
C84.5 Other and unspecified T-cell lymphomas
0.664 0.336 0.000
E07 Other disorders of thyroid
0.663 0.337 0.000
L41 Parapsoriasis
0.661 0.339 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.661 0.339 0.000
C88 Malignant immunoproliferative diseases
0.659 0.341 0.000
C02.8 Overlapping lesion of tongue
0.659 0.341 0.000
C02.0 Dorsal surface of tongue
0.659 0.341 0.000
C45.7 Mesothelioma of other sites
0.658 0.342 0.000
C84.0 Mycosis fungoides
0.657 0.342 0.000
C60 Malignant neoplasm of penis
0.653 0.344 0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.654 0.346 0.000
Q54.9 Hypospadias, unspecified
0.651 0.349 0.000
D02.0 Larynx
0.650 0.350 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.351 0.649
C18.8 Overlapping lesion of colon
0.647 0.353 0.000
D04 Carcinoma in situ of skin
0.647 0.353 0.000
D07.6 Other and unspecified male genital organs
0.645 0.355 0.000
D07.3 Other and unspecified female genital organs
0.645 0.355 0.000
D07.0 Endometrium
0.645 0.355 0.000
C20 Malignant neoplasm of rectum
0.645 0.355 0.000
L40.4 Guttate psoriasis
0.642 0.358 0.000
C62 Malignant neoplasm of testis
0.638 0.359 0.002
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.639 0.361 0.000
C91.1 Chronic lymphocytic leukaemia
0.639 0.361 0.000
E13.8 With unspecified complications
0.638 0.362 0.000
E13.7 With multiple complications
0.638 0.362 0.000
E13.6 With other specified complications
0.638 0.362 0.000
E13.5 With peripheral circulatory complications
0.638 0.362 0.000
E13.4 With neurological complications
0.638 0.362 0.000
E13.2 With renal complications
0.638 0.362 0.000
E13.1 With ketoacidosis
0.638 0.362 0.000
E13.0 With coma
0.638 0.362 0.000
C31 Malignant neoplasm of accessory sinuses
0.638 0.362 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.635 0.365 0.000
C84.4 Peripheral T-cell lymphoma
0.633 0.367 0.000
E24 Cushing's syndrome
0.629 0.371 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.629 0.371 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.371 0.629
C04.0 Anterior floor of mouth
0.627 0.373 0.000
G36 Other acute disseminated demyelination
0.000 0.373 0.627
C05 Malignant neoplasm of palate
0.626 0.374 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.624 0.375 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.624 0.375 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.624 0.375 0.000
C84.3 Lymphoepithelioid lymphoma
0.624 0.375 0.000
C84.2 T-zone lymphoma
0.624 0.375 0.000
C84.1 Sezary's diease
0.624 0.375 0.000
L40.8 Other psoriasis
0.623 0.377 0.000
D64.4 Congenital dyserythropoietic anaemia
0.622 0.378 0.000
D64.3 Other sideroblastic anaemias
0.622 0.378 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.622 0.378 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.622 0.378 0.000
D64.0 Hereditary sideroblastic anaemia
0.622 0.378 0.000
C02.4 Lingual tonsil
0.622 0.378 0.000
C16 Malignant neoplasm of stomach
0.621 0.379 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.618 0.382 0.000
D01.0 Colon
0.616 0.384 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.615 0.385 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.613 0.387 0.000
C04.8 Overlapping lesion of floor of mouth
0.613 0.387 0.000
C04.1 Lateral floor of mouth
0.613 0.387 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.390 0.610
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.390 0.610
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.390 0.610
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.390 0.610
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.390 0.610
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.390 0.610
C15.9 Oesophagus, unspecified
0.609 0.391 0.000
E13.3 With ophthalmic complications
0.608 0.392 0.000
L43.9 Lichen planus, unspecified
0.608 0.392 0.000
D02.2 Bronchus and lung
0.607 0.393 0.000
C10 Malignant neoplasm of oropharynx
0.605 0.394 0.000
E10.4 With neurological complications
0.604 0.396 0.000
Q50.5 Embryonic cyst of broad ligament
0.600 0.400 0.000
C60.9 Penis, unspecified
0.599 0.400 0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.600 0.400 0.000
D06 Carcinoma in situ of cervix uteri
0.599 0.401 0.000
Q38.1 Ankyloglossia
0.597 0.403 0.000
D09.0 Bladder
0.596 0.404 0.000
C32.8 Overlapping lesion of larynx
0.594 0.405 0.000
C32.3 Laryngeal cartilage
0.594 0.405 0.000
C32.2 Subglottis
0.594 0.405 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.406 0.594
Q45 Other congenital malformations of digestive system
0.593 0.407 0.000
L50.0 Allergic urticaria
0.593 0.407 0.000
C17.1 Jejunum
0.593 0.407 0.000
C83.6 Undifferentiated (diffuse)
0.593 0.407 0.000
C83.5 Lymphoblastic (diffuse)
0.593 0.407 0.000
C83.4 Immunoblastic (diffuse)
0.593 0.407 0.000
C83.2 Mixed small and large cell (diffuse)
0.593 0.407 0.000
L42 Pityriasis rosea
0.592 0.408 0.000
Q39 Congenital malformations of oesophagus
0.591 0.409 0.000
Q44.7 Other congenital malformations of liver
0.591 0.409 0.000
C83.7 Burkitt's tumour
0.590 0.410 0.000
Q40 Other congenital malformations of upper alimentary tract
0.588 0.411 0.000
C00 Malignant neoplasm of lip
0.588 0.412 0.000
D09.7 Carcinoma in situ of other specified sites
0.586 0.414 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.585 0.415 0.000
Q44.6 Cystic disease of liver
0.584 0.416 0.000
D07.2 Vagina
0.583 0.417 0.000
E11.6 With other specified complications
0.582 0.418 0.000
C38.3 Mediastinum, part unspecified
0.580 0.420 0.000
Q51.2 Other doubling of uterus
0.580 0.420 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.580 0.420 0.000
C46 Kaposi's sarcoma
0.580 0.420 0.000
E14.6 With other specified complications
0.579 0.421 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.579 0.421 0.000
L53 Other erythematous conditions
0.578 0.422 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.578 0.422 0.000
C93 Monocytic leukaemia
0.576 0.424 0.000
C95.7 Other leukaemia of unspecified cell type
0.576 0.424 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.576 0.424 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.576 0.424 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.425 0.575
G37.4 Subacute necrotising myelitis
0.000 0.425 0.575
G37.2 Central pontine myelinolysis
0.000 0.425 0.575
G37.1 Central demyelination of corpus callosum
0.000 0.425 0.575
G37.0 Diffuse sclerosis
0.000 0.425 0.575
C33 Malignant neoplasm of trachea
0.575 0.425 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.574 0.426 0.000
Q52 Other congenital malformations of female genitalia
0.574 0.426 0.000
Q35-Q37 Cleft lip and cleft palate
0.573 0.427 0.000
D64.8 Other specified anaemias
0.571 0.429 0.000
C83.1 Small cleaved cell (diffuse)
0.571 0.429 0.000
C38.4 Pleura
0.569 0.431 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.568 0.432 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.568 0.432 0.000
L54 Erythema in diseases classified elsewhere
0.568 0.432 0.000
D01.9 Digestive organ, unspecified
0.567 0.433 0.000
D01.7 Other specified digestive organs
0.567 0.433 0.000
D01.5 Liver, gallbladder and bile ducts
0.567 0.433 0.000
D01.4 Other and unspecified parts of intestine
0.567 0.433 0.000
D01.1 Rectosigmoid junction
0.567 0.433 0.000
Q44.5 Other congenital malformations of bile ducts
0.567 0.433 0.000
D04.5 Skin of trunk
0.567 0.433 0.000
Q03 Congenital hydrocephalus
0.565 0.435 0.000
C01 Malignant neoplasm of base of tongue
0.564 0.435 0.000
C06.0 Cheek mucosa
0.563 0.437 0.000
Q54.8 Other hypospadias
0.563 0.437 0.000
C91.9 Lymphoid leukaemia, unspecified
0.563 0.437 0.000
C13.0 Postcricoid region
0.562 0.438 0.000
C45.2 Mesothelioma of pericardium
0.561 0.439 0.000
C45.1 Mesothelioma of peritoneum
0.561 0.439 0.000
D02.4 Respiratory system, unspecified
0.560 0.440 0.000
D02.3 Other parts of respiratory system
0.560 0.440 0.000
D02.1 Trachea
0.560 0.440 0.000
D09.1 Other and unspecified urinary organs
0.559 0.441 0.000
C03.1 Lower gum
0.557 0.442 0.000
E07.8 Other specified disorders of thyroid
0.558 0.442 0.000
L44.9 Papulosquamous disorder, unspecified
0.556 0.444 0.000
L44.8 Other specified papulosquamous disorders
0.556 0.444 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.556 0.444 0.000
L44.3 Lichen ruber moniliformis
0.556 0.444 0.000
L44.2 Lichen striatus
0.556 0.444 0.000
L44.1 Lichen nitidus
0.556 0.444 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.555 0.445 0.000
C62.9 Testis, unspecified
0.554 0.446 0.000
L43.0 Hypertrophic lichen planus
0.552 0.448 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.552 0.448 0.000
C02.2 Ventral surface of tongue
0.551 0.449 0.000
Q43.0 Meckel's diverticulum
0.550 0.450 0.000
D01.2 Rectum
0.550 0.450 0.000
Q05 Spina bifida
0.550 0.450 0.000
E21.0 Primary hyperparathyroidism
0.549 0.451 0.000
E22 Hyperfunction of pituitary gland
0.548 0.452 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.546 0.454 0.000
C91.7 Other lymphoid leukaemia
0.546 0.454 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.546 0.454 0.000
C91.3 Prolymphocytic leukaemia
0.546 0.454 0.000
C91.2 Subacute lymphocytic leukaemia
0.546 0.454 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.546 0.454 0.000
E24.0 Pituitary-dependent Cushing's disease
0.544 0.456 0.000
Q55 Other congenital malformations of male genital organs
0.541 0.459 0.000
D09.3 Thyroid and other endocrine glands
0.541 0.459 0.000
D09.2 Eye
0.541 0.459 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.537 0.459 0.004
Q54.4 Congenital chordee
0.541 0.459 0.000
Q54.3 Hypospadias, perineal
0.541 0.459 0.000
Q54.2 Hypospadias, penoscrotal
0.541 0.459 0.000
Q53 Undescended testicle
0.540 0.460 0.000
K51 Ulcerative colitis
0.000 0.460 0.540
K90.3 Pancreatic steatorrhoea
0.540 0.460 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.540 0.460 0.000
K90.1 Tropical sprue
0.540 0.460 0.000
E25 Adrenogenital disorders
0.540 0.460 0.000
C91.5 Adult T-cell leukaemia
0.539 0.461 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.539 0.461 0.000
D00.1 Oesophagus
0.535 0.465 0.000
E11.3 With ophthalmic complications
0.532 0.468 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.532 0.468 0.000
D04.9 Skin, unspecified
0.530 0.470 0.000
Q04 Other congenital malformations of brain
0.530 0.470 0.000
D09.9 Carcinoma in situ, unspecified
0.528 0.472 0.000
Q54.0 Hypospadias, balanic
0.528 0.472 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.528 0.472 0.000
C91.0 Acute lymphoblastic leukaemia
0.526 0.474 0.000
C37 Malignant neoplasm of thymus
0.525 0.474 0.000
C32.1 Supraglottis
0.524 0.476 0.000
E31 Polyglandular dysfunction
0.524 0.476 0.000
L14 Bullous disorders in diseases classified elsewhere
0.524 0.476 0.000
Q80-Q89 Other congenital malformations
0.523 0.477 0.000
C03.9 Gum, unspecified
0.523 0.477 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.522 0.477 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.520 0.480 0.000
Q90 Down's syndrome
0.520 0.480 0.000
Q38.8 Other congenital malformations of pharynx
0.520 0.480 0.000
L50.1 Idiopathic urticaria
0.519 0.481 0.000
C16.6 Greater curvature of stomach, unspecified
0.519 0.481 0.000
C03.0 Upper gum
0.519 0.481 0.000
C16.8 Overlapping lesion of stomach
0.518 0.482 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.515 0.485 0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament
0.515 0.485 0.000
Q50.3 Other congenital malformations of ovary
0.515 0.485 0.000
Q50.2 Congenital torsion of ovary
0.515 0.485 0.000
Q50.1 Developmental ovarian cyst
0.515 0.485 0.000
Q50.0 Congenital absence of ovary
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.514 0.486 0.000
C38.2 Posterior mediastinum
0.514 0.486 0.000
C38.1 Anterior mediastinum
0.514 0.486 0.000
C38.0 Heart
0.514 0.486 0.000
C17.8 Overlapping lesion of small intestine
0.513 0.486 0.000
C17.3 Meckel's diverticulum
0.513 0.486 0.000
C13.8 Overlapping lesion of hypopharynx
0.513 0.487 0.000
C13.2 Posterior wall of hypopharynx
0.513 0.487 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.513 0.487 0.000
E10.5 With peripheral circulatory complications
0.512 0.488 0.000
Q44.4 Choledochal cyst
0.511 0.488 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.511 0.488 0.000
Q44.2 Atresia of bile ducts
0.511 0.488 0.000
Q44.1 Other congenital malformations of gallbladder
0.511 0.488 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.511 0.488 0.000
D80-D89 Certain disorders involving the immune mechanism
0.511 0.489 0.000
L50.9 Urticaria, unspecified
0.510 0.490 0.000
C18.5 Splenic flexure
0.510 0.490 0.000
Q96 Turner's syndrome
0.509 0.491 0.000
L43.3 Subacute (active) lichen planus
0.506 0.494 0.000
L43.2 Lichenoid drug reaction
0.506 0.494 0.000
L43.1 Bullous lichen planus
0.506 0.494 0.000
C17.2 Ileum
0.505 0.495 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.505 0.495 0.000
C06.1 Vestibule of mouth
0.505 0.495 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.505 0.495 0.000
E32 Diseases of thymus
0.505 0.495 0.000
E30 Disorders of puberty, not elsewhere classified
0.505 0.495 0.000
C18.0 Caecum
0.505 0.495 0.000
C94.7 Other specified leukaemias
0.504 0.495 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.504 0.495 0.000
C94.5 Acute myelofibrosis
0.504 0.495 0.000
C94.4 Acute panmyelosis
0.504 0.495 0.000
C94.3 Mast cell leukaemia
0.504 0.495 0.000
C94.2 Acute megakaryoblastic leukaemia
0.504 0.495 0.000
C94.1 Chronic erythraemia
0.504 0.495 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.504 0.495 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.504 0.495 0.000
C96.8 Histiocytic sarcoma
0.504 0.495 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.504 0.495 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.504 0.495 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.504 0.495 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.504 0.495 0.000
C96.3 True histiocytic lymphoma
0.504 0.495 0.000
C96.2 Malignant mast cell tumour
0.504 0.495 0.000
C96.1 Malignant histiocytosis
0.504 0.495 0.000
C96.0 Letterer-Siwe disease
0.504 0.495 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.503 0.497 0.000
L13.9 Bullous disorder, unspecified
0.502 0.497 0.000
L13.8 Other specified bullous disorders
0.502 0.497 0.000
L13.1 Subcorneal pustular dermatitis
0.502 0.497 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.501 0.499 0.000
E45 Retarded development following protein-energy malnutrition
0.501 0.499 0.000
E43 Unspecified severe protein-energy malnutrition
0.501 0.499 0.000
E42 Marasmic kwashiorkor
0.501 0.499 0.000
E41 Nutritional marasmus
0.501 0.499 0.000
E40 Kwashiorkor
0.501 0.499 0.000
C17.9 Small intestine, unspecified
0.501 0.499 0.000
E28 Ovarian dysfunction
0.500 0.500 0.000
D00.2 Stomach
0.500 0.500 0.000
C95.0 Acute leukaemia of unspecified cell type
0.499 0.500 0.000
E21.2 Other hyperparathyroidism
0.499 0.501 0.000
E24.9 Cushing's syndrome, unspecified
0.499 0.501 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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