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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4446587
log Bayes Factor = 54.1423
Chromosome 6   position 29,259,623  (GRCh37) Explore rs4446587 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E00-E07 Disorders of thyroid gland
0.000 0.006 0.994
E10.3 With ophthalmic complications
0.000 0.021 0.979
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.031 0.969
E10.2 With renal complications
0.000 0.046 0.954
E10.1 With ketoacidosis
0.000 0.071 0.929
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.141 0.859
E10.4 With neurological complications
0.000 0.161 0.839
E16.1 Other hypoglycaemia
0.000 0.194 0.805
E05.8 Other thyrotoxicosis
0.000 0.208 0.792
E13 Other specified diabetes mellitus
0.000 0.215 0.785
E10.7 With multiple complications
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.287 0.713
E00 Congenital iodine-deficiency syndrome
0.000 0.287 0.713
E40-E46 Malnutrition
0.000 0.302 0.698
E10.0 With coma
0.000 0.306 0.694
E10.6 With other specified complications
0.000 0.329 0.671
E14 Unspecified diabetes mellitus
0.000 0.340 0.660
E13.9 Without complications
0.000 0.343 0.657
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.362 0.638
E07 Other disorders of thyroid
0.000 0.377 0.623
E06 Thyroiditis
0.000 0.396 0.604
E14.3 With ophthalmic complications
0.000 0.420 0.580
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.577 0.423 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.423 0.576
E10.5 With peripheral circulatory complications
0.000 0.434 0.566
E13.8 With unspecified complications
0.000 0.437 0.563
E13.7 With multiple complications
0.000 0.437 0.563
E13.6 With other specified complications
0.000 0.437 0.563
E13.5 With peripheral circulatory complications
0.000 0.437 0.563
E13.4 With neurological complications
0.000 0.437 0.563
E13.2 With renal complications
0.000 0.437 0.563
E13.1 With ketoacidosis
0.000 0.437 0.563
E13.0 With coma
0.000 0.437 0.563
E13.3 With ophthalmic complications
0.000 0.479 0.521
E14.8 With unspecified complications
0.000 0.484 0.516
E12.9 Without complications
0.000 0.487 0.512
E12.8 With unspecified complications
0.000 0.487 0.512
E12.7 With multiple complications
0.000 0.487 0.512
E12.6 With other specified complications
0.000 0.487 0.512
E12.5 With peripheral circulatory complications
0.000 0.487 0.512
E12.4 With neurological complications
0.000 0.487 0.512
E12.3 With ophthalmic complications
0.000 0.487 0.512
E12.2 With renal complications
0.000 0.487 0.512
E12.1 With ketoacidosis
0.000 0.487 0.512
E12.0 With coma
0.000 0.487 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
E10.8 With unspecified complications
0.000 0.490 0.510
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.500 0.500
E45 Retarded development following protein-energy malnutrition
0.000 0.500 0.500
E43 Unspecified severe protein-energy malnutrition
0.000 0.500 0.500
E42 Marasmic kwashiorkor
0.000 0.500 0.500
E41 Nutritional marasmus
0.000 0.500 0.500
E40 Kwashiorkor
0.000 0.500 0.500
E14.1 With ketoacidosis
0.000 0.500 0.500
E07.8 Other specified disorders of thyroid
0.000 0.505 0.495
E14.4 With neurological complications
0.000 0.508 0.492
E06.9 Thyroiditis, unspecified
0.000 0.508 0.492
E14.6 With other specified complications
0.000 0.516 0.484
E46 Unspecified protein-energy malnutrition
0.000 0.516 0.483
E14.7 With multiple complications
0.000 0.526 0.473
E06.1 Subacute thyroiditis
0.000 0.546 0.454
E07.1 Dyshormogenetic goitre
0.000 0.553 0.446
E07.0 Hypersecretion of calcitonin
0.000 0.553 0.446
E14.0 With coma
0.000 0.556 0.443
K90 Intestinal malabsorption
0.000 0.563 0.437
E06.4 Drug-induced thyroiditis
0.000 0.567 0.433
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.567 0.433
E06.0 Acute thyroiditis
0.000 0.567 0.433
E14.2 Withrenal complications
0.000 0.567 0.432
E14.5 With peripheral circulatory complications
0.000 0.572 0.428
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.582 0.417
E06.5 Other chronic thyroiditis
0.000 0.584 0.416
E03 Other hypothyroidism
0.000 0.612 0.388
E44.1 Mild protein-energy malnutrition
0.000 0.641 0.359
E44.0 Moderate protein-energy malnutrition
0.000 0.641 0.359
E65-E68 Obesity and other hyperalimentation
0.000 0.644 0.356
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.644 0.356
K90.3 Pancreatic steatorrhoea
0.000 0.687 0.313
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.687 0.313
K90.1 Tropical sprue
0.000 0.687 0.313
K90.8 Other intestinal malabsorption
0.000 0.700 0.300
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.709 0.291
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.720 0.279
E03.5 Myxoedema coma
0.000 0.721 0.278
E03.4 Atrophy of thyroid (acquired)
0.000 0.721 0.278
E03.3 Postinfectious hypothyroidism
0.000 0.721 0.278
K90.9 Intestinal malabsorption, unspecified
0.000 0.731 0.269
E50-E64 Other nutritional deficiencies
0.000 0.732 0.268
E03.1 Congenital hypothyroidism without goitre
0.000 0.743 0.257
E67 Other hyperalimentation
0.000 0.744 0.255
E68 Sequelae of hyperalimentation
0.000 0.744 0.255
E07.9 Disorder of thyroid, unspecified
0.000 0.745 0.255
E20-E35 Disorders of other endocrine glands
0.000 0.747 0.253
R31 Unspecified haematuria
0.253 0.747 0.000
E24 Cushing's syndrome
0.000 0.765 0.235
E03.8 Other specified hypothyroidism
0.000 0.771 0.228
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.774 0.226
E83 Disorders of mineral metabolism
0.224 0.775 0.001
E21.3 Hyperparathyroidism, unspecified
0.000 0.784 0.216
E65 Localised adiposity
0.000 0.785 0.215
E83.3 Disorders of phosphorus metabolism
0.202 0.798 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.800 0.200
E24.9 Cushing's syndrome, unspecified
0.000 0.802 0.197
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.807 0.192
E50 Vitamin A deficiency
0.000 0.807 0.192
E60 Dietary zinc deficiency
0.000 0.807 0.192
E59 Dietary selenium deficiency
0.000 0.807 0.192
E52 Niacin deficiency [pellagra]
0.000 0.807 0.192
E51 Thiamine deficiency
0.000 0.809 0.191
E24.2 Drug-induced Cushing's syndrome
0.000 0.811 0.189
E54 Ascorbic acid deficiency
0.000 0.812 0.188
E67.8 Other specified hyperalimentation
0.000 0.817 0.183
E67.3 Hypervitaminosis D
0.000 0.817 0.183
E67.2 Megavitamin-B6 syndrome
0.000 0.817 0.183
E67.1 Hypercarotenaemia
0.000 0.817 0.183
E67.0 Hypervitaminosis A
0.000 0.817 0.183
E56 Other vitamin deficiencies
0.000 0.818 0.182
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.818 0.182
E32 Diseases of thymus
0.000 0.818 0.182
E30 Disorders of puberty, not elsewhere classified
0.000 0.818 0.182
E25 Adrenogenital disorders
0.000 0.819 0.181
E20 Hypoparathyroidism
0.000 0.820 0.180
E21.4 Other specified disorders of parathyroid gland
0.000 0.824 0.176
E58 Dietary calcium deficiency
0.000 0.824 0.175
E63 Other nutritional deficiencies
0.000 0.826 0.174
E31 Polyglandular dysfunction
0.000 0.827 0.173
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.828 0.171
E24.8 Other Cushing's syndrome
0.000 0.831 0.168
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.831 0.168
E24.3 Ectopic ACTH syndrome
0.000 0.831 0.168
E24.1 Nelson's syndrome
0.000 0.831 0.168
E28 Ovarian dysfunction
0.000 0.835 0.165
E21.2 Other hyperparathyroidism
0.000 0.837 0.163
E83.8 Other disorders of mineral metabolism
0.161 0.838 0.001
E83.2 Disorders of zinc metabolism
0.161 0.838 0.001
E83.0 Disorders of copper metabolism
0.161 0.838 0.001
E83.9 Disorder of mineral metabolism, unspecified
0.160 0.839 0.001
E06.3 Autoimmune thyroiditis
0.001 0.839 0.161
E55 Vitamin D deficiency
0.000 0.846 0.154
E61 Deficiency of other nutrient elements
0.000 0.850 0.149
E53 Deficiency of other B group vitamins
0.000 0.851 0.149
E29 Testicular dysfunction
0.000 0.852 0.148
E34 Other endocrine disorders
0.000 0.856 0.143
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.860 0.139
E50.9 Vitamin A deficiency, unspecified
0.000 0.862 0.138
E50.8 Other manifestations of vitamin A deficiency
0.000 0.862 0.138
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.862 0.138
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.862 0.138
E50.5 Vitamin A deficiency with night blindness
0.000 0.862 0.138
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.862 0.138
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.862 0.138
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.862 0.138
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.862 0.138
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.862 0.138
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.862 0.138
E64.8 Sequelae of other nutritional deficiencies
0.000 0.862 0.138
E64.3 Sequelae of rickets
0.000 0.862 0.138
E64.2 Sequelae of vitamin C deficiency
0.000 0.862 0.138
E64.1 Sequelae of vitamin A deficiency
0.000 0.862 0.138
E64.0 Sequelae of protein-energy malnutrition
0.000 0.862 0.138
E51.9 Thiamine deficiency, unspecified
0.000 0.863 0.137
E51.8 Other manifestations of thiamine deficiency
0.000 0.863 0.137
E51.1 Beriberi
0.000 0.863 0.137
E22 Hyperfunction of pituitary gland
0.000 0.864 0.136
E51.2 Wernicke's encephalopathy
0.000 0.864 0.136
E56.9 Vitamin deficiency, unspecified
0.000 0.869 0.131
E56.8 Deficiency of other vitamins
0.000 0.869 0.131
E56.0 Deficiency of vitamin E
0.000 0.869 0.131
E30.9 Disorder of puberty, unspecified
0.000 0.869 0.130
E30.8 Other disorders of puberty
0.000 0.869 0.130
E30.1 Precocious puberty
0.000 0.869 0.130
E30.0 Delayed puberty
0.000 0.869 0.130
E32.9 Disease of thymus, unspecified
0.000 0.869 0.130
E32.8 Other diseases of thymus
0.000 0.869 0.130
E32.1 Abscess of thymus
0.000 0.869 0.130
E32.0 Persistent hyperplasia of thymus
0.000 0.869 0.130
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.869 0.130
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.869 0.130
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.869 0.130
E25.9 Adrenogenital disorder, unspecified
0.000 0.870 0.130
E25.8 Other adrenogenital disorders
0.000 0.870 0.130
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.871 0.129
E20.8 Other hypoparathyroidism
0.000 0.871 0.129
E20.1 Pseudohypoparathyroidism
0.000 0.871 0.129
E20.0 Idiopathic hypoparathyroidism
0.000 0.871 0.129
E20.9 Hypoparathyroidism, unspecified
0.000 0.873 0.127
E63.8 Other specified nutritional deficiencies
0.000 0.875 0.125
E63.1 Imbalance of constituents of food intake
0.000 0.875 0.125
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.875 0.125
E31.9 Polyglandular dysfunction, unspecified
0.000 0.875 0.124
E31.8 Other polyglandular dysfunction
0.000 0.875 0.124
E31.1 Polyglandular hyperfunction
0.000 0.875 0.124
E11 Non-insulin-dependent diabetes mellitus
0.000 0.876 0.124
E56.1 Deficiency of vitamin K
0.000 0.879 0.120
E26 Hyperaldosteronism
0.000 0.880 0.119
E28.9 Ovarian dysfunction, unspecified
0.000 0.881 0.118
E28.8 Other ovarian dysfunction
0.000 0.881 0.118
E28.1 Androgen excess
0.000 0.881 0.118
E28.0 Oestrogen excess
0.000 0.881 0.118
E31.0 Autoimmune polyglandular failure
0.000 0.884 0.116
E53.9 Vitamin B deficiency, unspecified
0.000 0.886 0.114
E28.2 Polycystic ovarian syndrome
0.000 0.886 0.114
E11.6 With other specified complications
0.000 0.888 0.112
E55.0 Rickets, active
0.000 0.889 0.111
E28.3 Primary ovarian failure
0.000 0.892 0.108
E61.9 Deficiency of nutrient element, unspecified
0.000 0.893 0.107
E61.8 Deficiency of other specified nutrient elements
0.000 0.893 0.107
E61.7 Deficiency of multiple nutrient elements
0.000 0.893 0.107
E61.6 Vanadium deficiency
0.000 0.893 0.107
E61.5 Molybdenum deficiency
0.000 0.893 0.107
E61.4 Chromium deficiency
0.000 0.893 0.107
E61.3 Manganese deficiency
0.000 0.893 0.107
E61.0 Copper deficiency
0.000 0.893 0.107
E53.1 Pyridoxine deficiency
0.000 0.893 0.107
E53.0 Riboflavin deficiency
0.000 0.893 0.107
E63.9 Nutritional deficiency, unspecified
0.000 0.893 0.106
E29.9 Testicular dysfunction, unspecified
0.000 0.894 0.106
E29.8 Other testicular dysfunction
0.000 0.894 0.106
E29.0 Testicular hyperfunction
0.000 0.894 0.106
E34.3 Short stature, not elsewhere classified
0.000 0.895 0.104
E22.1 Hyperprolactinaemia
0.000 0.896 0.104
E03.9 Hypothyroidism, unspecified
0.000 0.896 0.104
E34.5 Androgen resistance syndrome
0.000 0.897 0.103
E34.4 Constitutional tall stature
0.000 0.897 0.103
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.897 0.103
E34.1 Other hypersecretion of intestinal hormones
0.000 0.897 0.103
E34.9 Endocrine disorder, unspecified
0.000 0.901 0.099
E22.8 Other hyperfunction of pituitary gland
0.000 0.902 0.098
E21.0 Primary hyperparathyroidism
0.000 0.904 0.096
E14.9 Without complications
0.000 0.906 0.094
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.906 0.094
E11.1 With ketoacidosis
0.000 0.907 0.093
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.908 0.092
E61.2 Magnesium deficiency
0.000 0.910 0.090
E83.4 Disorders of magnesium metabolism
0.090 0.910 0.000
E34.0 Carcinoid syndrome
0.000 0.910 0.090
E11.7 With multiple complications
0.000 0.911 0.089
E61.1 Iron deficiency
0.000 0.911 0.089
E34.8 Other specified endocrine disorders
0.000 0.912 0.088
E11.0 With coma
0.000 0.912 0.088
E26.8 Other hyperaldosteronism
0.000 0.914 0.086
E26.1 Secondary hyperaldosteronism
0.000 0.914 0.086
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.918 0.082
E11.2 With renal complications
0.000 0.918 0.082
C20 Malignant neoplasm of rectum
0.000 0.923 0.077
E26.9 Hyperaldosteronism, unspecified
0.001 0.924 0.075
E23 Hypofunction and other disorders of pituitary gland
0.000 0.925 0.075
E22.0 Acromegaly and pituitary gigantism
0.000 0.925 0.075
E11.8 With unspecified complications
0.000 0.926 0.074
I83 Varicose veins of lower extremities
0.074 0.926 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.927 0.072
E29.1 Testicular hypofunction
0.000 0.928 0.072
C15-C26 Malignant neoplasms of digestive organs
0.000 0.928 0.072
C25 Malignant neoplasm of pancreas
0.000 0.933 0.067
C15 Malignant neoplasm of oesophagus
0.000 0.938 0.062
E23.7 Disorder of pituitary gland, unspecified
0.000 0.940 0.060
C25.1 Body of pancreas
0.000 0.941 0.059
C25.3 Pancreatic duct
0.000 0.942 0.058
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.944 0.056
C25.2 Tail of pancreas
0.000 0.944 0.056
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.946 0.054
E23.1 Drug-induced hypopituitarism
0.000 0.946 0.054
C17 Malignant neoplasm of small intestine
0.000 0.946 0.054
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.947 0.053
E04 Other non-toxic goitre
0.002 0.947 0.051
E11.5 With peripheral circulatory complications
0.000 0.947 0.053
C15.4 Middle third of oesophagus
0.000 0.948 0.052
C25.4 Endocrine pancreas
0.000 0.948 0.052
C25.9 Pancreas, unspecified
0.000 0.948 0.052
C17.0 Duodenum
0.000 0.948 0.052
C15.5 Lower third of oesophagus
0.000 0.948 0.052
C25.8 Overlapping lesion of pancreas
0.000 0.949 0.051
C24.0 Extrahepatic bile duct
0.000 0.950 0.050
E11.3 With ophthalmic complications
0.000 0.950 0.050
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.048 0.952 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.953 0.047
E26.0 Primary hyperaldosteronism
0.001 0.953 0.046
C15.0 Cervical part of oesophagus
0.000 0.954 0.046
C15.8 Overlapping lesion of oesophagus
0.000 0.955 0.044
C15.2 Abdominal part of oesophagus
0.000 0.955 0.044
C25.7 Other parts of pancreas
0.000 0.956 0.044
S02.4 Fracture of malar and maxillary bones
0.000 0.957 0.043
C15.1 Thoracic part of oesophagus
0.000 0.957 0.043
C15.9 Oesophagus, unspecified
0.000 0.958 0.042
C15.3 Upper third of oesophagus
0.000 0.958 0.041
C24.9 Biliary tract, unspecified
0.000 0.959 0.041
I83.0 Varicose veins of lower extremities with ulcer
0.041 0.959 0.000
Z71.8 Other specified counselling
0.040 0.960 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.960 0.040
E27 Other disorders of adrenal gland
0.000 0.961 0.039
C17.8 Overlapping lesion of small intestine
0.000 0.961 0.039
C17.3 Meckel's diverticulum
0.000 0.961 0.039
E23.6 Other disorders of pituitary gland
0.000 0.961 0.038
E04.8 Other specified non-toxic goitre
0.001 0.962 0.037
S02 Fracture of skull and facial bones
0.000 0.962 0.038
C17.1 Jejunum
0.000 0.963 0.036
C21 Malignant neoplasm of anus and anal canal
0.000 0.964 0.036
E23.2 Diabetes insipidus
0.000 0.964 0.035
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.965 0.035
C23 Malignant neoplasm of gallbladder
0.000 0.966 0.034
S02.8 Fractures of other skull and facial bones
0.000 0.967 0.033
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.968 0.032
S02.0 Fracture of vault of skull
0.000 0.968 0.032
E11.4 With neurological complications
0.000 0.969 0.031
S02.3 Fracture of orbital floor
0.000 0.970 0.030
S02.5 Fracture of tooth
0.000 0.970 0.030
S02.7 Multiple fractures involving skull and facial bones
0.000 0.970 0.030
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.971 0.029
E66 Obesity
0.000 0.971 0.029
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.971 0.029
S02.6 Fracture of mandible
0.000 0.971 0.029
K14.8 Other diseases of tongue
0.000 0.971 0.029
C25.0 Head of pancreas
0.000 0.971 0.028
E27.5 Adrenomedullary hyperfunction
0.000 0.972 0.028
E27.0 Other adrenocortical overactivity
0.000 0.972 0.028
S02.00 Fracture of vault of skull (closed)
0.000 0.972 0.028
C17.9 Small intestine, unspecified
0.000 0.972 0.027
E04.0 Non-toxic diffuse goitre
0.002 0.972 0.026
E27.1 Primary adrenocortical insufficiency
0.000 0.973 0.027
K90-K93 Other diseases of the digestive system
0.000 0.973 0.027
C22.9 Liver, unspecified
0.000 0.973 0.027
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.974 0.026
C21.2 Cloacogenic zone
0.000 0.974 0.026
C22.7 Other specified carcinomas of liver
0.000 0.974 0.025
C22.4 Other sarcomas of liver
0.000 0.974 0.025
C22.3 Angiosarcoma of liver
0.000 0.974 0.025
C22.2 Hepatoblastoma
0.000 0.974 0.025
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.975 0.025
E27.9 Disorder of adrenal gland, unspecified
0.000 0.975 0.025
S02.30 Fracture of orbital floor (closed)
0.000 0.975 0.025
S02.2 Fracture of nasal bones
0.000 0.975 0.025
S02.50 Fracture of tooth (closed)
0.000 0.976 0.024
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.976 0.024
C22.1 Intrahepatic bile duct carcinoma
0.000 0.976 0.024
S02.81 Fractures of other skull and facial bones (open)
0.000 0.976 0.024
S02.1 Fracture of base of skull
0.000 0.977 0.023
C26.8 Overlapping lesion of digestive system
0.000 0.977 0.023
C26.1 Spleen
0.000 0.977 0.023
S02.01 Fracture of vault of skull (open)
0.000 0.977 0.023
C17.2 Ileum
0.000 0.977 0.023
S02.60 Fracture of mandible (closed)
0.000 0.977 0.023
C24.1 Ampulla of Vater
0.000 0.978 0.022
E27.2 Addisonian crisis
0.000 0.978 0.022
E11.9 Without complications
0.000 0.978 0.022
S02.31 Fracture of orbital floor (open)
0.000 0.978 0.022
S02.51 Fracture of tooth (open)
0.000 0.978 0.021
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.978 0.021
E66.1 Drug-induced obesity
0.000 0.979 0.021
S02.61 Fracture of mandible (open)
0.000 0.979 0.021
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.979 0.020
S02.21 Fracture of nasal bones (open)
0.000 0.979 0.021
C21.1 Anal canal
0.000 0.980 0.020
I83.1 Varicose veins of lower extremities with inflammation
0.020 0.980 0.000
E23.0 Hypopituitarism
0.000 0.980 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.019
C21.0 Anus, unspecified
0.000 0.980 0.019
C18.9 Colon, unspecified
0.000 0.980 0.020
C18 Malignant neoplasm of colon
0.000 0.981 0.019
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.981 0.018
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.981 0.018
S02.11 Fracture of base of skull (open)
0.000 0.982 0.018
C18.1 Appendix
0.000 0.982 0.018
E27.8 Other specified disorders of adrenal gland
0.000 0.982 0.017
C26.9 Ill-defined sites within the digestive system
0.000 0.982 0.017
E66.0 Obesity due to excess calories
0.000 0.983 0.017
C16 Malignant neoplasm of stomach
0.000 0.983 0.017
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.983 0.016
H40.2 Primary angle-closure glaucoma
0.017 0.983 0.000
E04.9 Non-toxic goitre, unspecified
0.001 0.984 0.016
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.985 0.015
C26.0 Intestinal tract, part unspecified
0.000 0.986 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.014
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.014
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.014
C18.8 Overlapping lesion of colon
0.000 0.986 0.014
E83.5 Disorders of calcium metabolism
0.014 0.986 0.001
S05 Injury of eye and orbit
0.000 0.986 0.014
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.014 0.986 0.000
C16.5 Lesser curvature of stomach, unspecified
0.000 0.987 0.013
E70-E90 Metabolic disorders
0.004 0.987 0.009
S00-S09 Injuries to the head
0.000 0.987 0.013
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.987 0.013
C16.8 Overlapping lesion of stomach
0.000 0.988 0.012
S05.8 Other injuries of eye and orbit
0.000 0.988 0.012
C16.2 Body of stomach
0.000 0.988 0.012
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.988 0.012
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.988 0.012
C16.4 Pylorus
0.000 0.988 0.011
C16.6 Greater curvature of stomach, unspecified
0.000 0.989 0.011
K14 Diseases of tongue
0.000 0.989 0.011
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.989 0.011
C16.9 Stomach, unspecified
0.000 0.989 0.011
C18.7 Sigmoid colon
0.000 0.989 0.011
S05.1 Contusion of eyeball and orbital tissues
0.000 0.989 0.011
S00 Superficial injury of head
0.000 0.989 0.011
K14.6 Glossodynia
0.000 0.989 0.011
C16.1 Fundus of stomach
0.000 0.989 0.010
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.990 0.010
S02.20 Fracture of nasal bones (closed)
0.000 0.990 0.010
C16.3 Pyloric antrum
0.000 0.990 0.010
C18.4 Transverse colon
0.000 0.990 0.010
S05.7 Avulsion of eye
0.000 0.990 0.010
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.990 0.010
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.990 0.010
S02.10 Fracture of base of skull (closed)
0.000 0.990 0.010
S08 Traumatic amputation of part of head
0.000 0.990 0.010
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.990 0.010
C22.0 Liver cell carcinoma
0.000 0.990 0.010
E77 Disorders of glycoprotein metabolism
0.003 0.990 0.006
E76 Disorders of glycosaminoglycan metabolism
0.003 0.990 0.006
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.990 0.006
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.990 0.006
S07 Crushing injury of head
0.000 0.990 0.010
S04 Injury of cranial nerves
0.000 0.990 0.010
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.003 0.990 0.007
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.990 0.009
E70 Disorders of aromatic amino-acid metabolism
0.003 0.990 0.006
E74 Other disorders of carbohydrate metabolism
0.003 0.990 0.007
E72 Other disorders of amino-acid metabolism
0.003 0.990 0.006
C18.6 Descending colon
0.000 0.991 0.009
E79 Disorders of purine and pyrimidine metabolism
0.004 0.991 0.006
E73 Lactose intolerance
0.003 0.991 0.007
S00.0 Superficial injury of scalp
0.000 0.991 0.009
E84 Cystic fibrosis
0.004 0.991 0.006
S00.4 Superficial injury of ear
0.000 0.991 0.009
S00.1 Contusion of eyelid and periocular area
0.000 0.991 0.009
E85 Amyloidosis
0.003 0.991 0.006
S05.9 Injury of eye and orbit, part unspecified
0.000 0.991 0.009
R30-R39 Symptoms and signs involving the urinary system
0.009 0.991 0.000
C16.0 Cardia
0.000 0.991 0.009
M45.X9 Ankylosing spondylitis (Site unspecified)
0.009 0.991 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.991 0.009
K14.1 Geographic tongue
0.000 0.991 0.008
K14.3 Hypertrophy of tongue papillae
0.000 0.991 0.008
I97.1 Other functional disturbances following cardiac surgery
0.000 0.992 0.008
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.992 0.008
K14.5 Plicated tongue
0.000 0.992 0.008
K14.4 Atrophy of tongue papillae
0.000 0.992 0.008
S09 Other and unspecified injuries of head
0.000 0.992 0.008
S00.7 Multiple superficial injuries of head
0.000 0.992 0.008
S08.1 Traumatic amputation of ear
0.000 0.992 0.008
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.992 0.008
C18.3 Hepatic flexure
0.000 0.992 0.008
R34 Anuria and oliguria
0.008 0.992 0.000
E88 Other metabolic disorders
0.002 0.992 0.006
J98.1 Pulmonary collapse
0.008 0.992 0.000
S08.9 Traumatic amputation of unspecified part of head
0.000 0.992 0.007
S08.8 Traumatic amputation of other parts of head
0.000 0.992 0.007
S08.0 Avulsion of scalp
0.000 0.992 0.007
S09.8 Other specified injuries of head
0.000 0.992 0.008
K14.2 Median rhomboid glossitis
0.000 0.993 0.007
E71.3 Disorders of fatty-acid metabolism
0.003 0.993 0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.003 0.993 0.005
E71.1 Other disorders of branched-chain amino-acid metabolism
0.003 0.993 0.005
E71.0 Maple-syrup-urine disease
0.003 0.993 0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.003 0.993 0.005
E76.8 Other disorders of glucosaminoglycan metabolism
0.003 0.993 0.005
E76.3 Mucopolysaccharidosis, unspecified
0.003 0.993 0.005
E76.2 Other mucopolysaccharidoses
0.003 0.993 0.005
E76.1 Mucopolysaccharidosis, type II
0.003 0.993 0.005
E76.0 Mucopolysaccharidosis, type I
0.003 0.993 0.005
E77.9 Disorder of glycoprotein metabolism, unspecified
0.003 0.993 0.005
E77.8 Other disorders of glycoprotein metabolism
0.003 0.993 0.005
E77.1 Defects in glycoprotein degradation
0.003 0.993 0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.003 0.993 0.005
K14.0 Glossitis
0.000 0.993 0.007
S04.9 Injury of unspecified cranial nerve
0.000 0.993 0.007
S04.8 Injury of other cranial nerves
0.000 0.993 0.007
S04.7 Injury of accessory nerve
0.000 0.993 0.007
S04.6 Injury of acoustic nerve
0.000 0.993 0.007
S04.5 Injury of facial nerve
0.000 0.993 0.007
S04.4 Injury of abducent nerve
0.000 0.993 0.007
S04.3 Injury of trigeminal nerve
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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