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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs444921
log Bayes Factor = 40.0094
Chromosome 6   position 31,932,177  (GRCh37) Explore rs444921 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
M06 Other rheumatoid arthritis
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.004 0.996
E10.1 With ketoacidosis
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
E11.3 With ophthalmic complications
0.000 0.018 0.982
M05-M14 Inflammatory polyarthropathies
0.000 0.020 0.980
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.025 0.975
M05 Seropositive rheumatoid arthritis
0.000 0.033 0.967
M06.0 Seronegative rheumatoid arthritis
0.000 0.035 0.965
E65-E68 Obesity and other hyperalimentation
0.000 0.040 0.960
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.042 0.958
L20-L30 Dermatitis and eczema
0.000 0.046 0.954
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.048 0.952
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.057 0.943
E10.5 With peripheral circulatory complications
0.000 0.061 0.939
L27 Dermatitis due to substances taken internally
0.000 0.064 0.936
E66 Obesity
0.000 0.069 0.931
L40-L45 Papulosquamous disorders
0.000 0.069 0.931
E66.8 Other obesity
0.000 0.071 0.929
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.073 0.927
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.076 0.924
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.077 0.923
L40 Psoriasis
0.000 0.091 0.909
E11.5 With peripheral circulatory complications
0.000 0.091 0.909
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.096 0.904
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.096 0.904
L30 Other dermatitis
0.000 0.096 0.904
E14 Unspecified diabetes mellitus
0.000 0.097 0.903
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.102 0.898
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.102 0.898
L29 Pruritus
0.000 0.104 0.896
L57.0 Actinic keratosis
0.000 0.118 0.882
L30.9 Dermatitis, unspecified
0.000 0.123 0.877
E10.4 With neurological complications
0.000 0.125 0.875
L40.5 Arthropathic psoriasis
0.000 0.127 0.873
L08 Other local infections of skin and subcutaneous tissue
0.000 0.129 0.871
E10.2 With renal complications
0.000 0.129 0.871
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.132 0.868
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.133 0.867
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.143 0.857
E11.9 Without complications
0.000 0.144 0.856
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.148 0.852
L29.0 Pruritus ani
0.000 0.151 0.849
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.151 0.849
M06.3 Rheumatoid nodule
0.000 0.159 0.840
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.165 0.835
E14.9 Without complications
0.000 0.166 0.834
E11.2 With renal complications
0.000 0.175 0.825
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.184 0.816
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.197 0.803
M07 Psoriatic and enteropathic arthropathies
0.000 0.197 0.803
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.209 0.791
L21 Seborrhoeic dermatitis
0.000 0.213 0.787
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.214 0.786
L40.0 Psoriasis vulgaris
0.000 0.217 0.783
E06 Thyroiditis
0.000 0.218 0.782
L43 Lichen planus
0.000 0.228 0.772
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.228 0.772
M14 Arthropathies in other diseases classified elsewhere
0.000 0.244 0.756
E10.6 With other specified complications
0.000 0.246 0.754
E14.3 With ophthalmic complications
0.000 0.251 0.748
M10 Gout
0.000 0.260 0.740
E10.8 With unspecified complications
0.000 0.269 0.731
M35 Other systemic involvement of connective tissue
0.000 0.275 0.725
M35.3 Polymyalgia rheumatica
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
M35.0 Sicca syndrome [Sjogren]
0.000 0.284 0.716
M06.8 Other specified rheumatoid arthritis
0.000 0.284 0.716
M06.2 Rheumatoid bursitis
0.000 0.284 0.716
M06.1 Adult-onset Still's disease
0.000 0.284 0.716
E11.7 With multiple complications
0.000 0.285 0.714
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.291 0.709
E11.8 With unspecified complications
0.000 0.296 0.704
M12 Other specific arthropathies
0.000 0.297 0.703
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.297 0.703
M08 Juvenile arthritis
0.000 0.297 0.703
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.297 0.703
M13 Other arthritis
0.000 0.299 0.701
M06.34 Rheumatoid nodule (Hand)
0.000 0.300 0.700
M05.8 Other seropositive rheumatoid arthritis
0.000 0.307 0.693
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.307 0.693
M05.2 Rheumatoid vasculitis
0.000 0.307 0.693
M05.1 Rheumatoid lung disease
0.000 0.307 0.693
M05.0 Felty's syndrome
0.000 0.307 0.693
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.308 0.692
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.308 0.692
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.308 0.692
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.308 0.692
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.308 0.692
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.308 0.692
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.308 0.692
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.308 0.692
L29.8 Other pruritus
0.000 0.309 0.691
E11.4 With neurological complications
0.000 0.309 0.691
E67 Other hyperalimentation
0.000 0.312 0.688
E68 Sequelae of hyperalimentation
0.000 0.312 0.688
E05.8 Other thyrotoxicosis
0.000 0.312 0.688
E11.0 With coma
0.000 0.313 0.687
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.313 0.686
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.313 0.686
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.313 0.686
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.313 0.686
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.313 0.686
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.313 0.686
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.313 0.686
E65 Localised adiposity
0.000 0.315 0.685
L25 Unspecified contact dermatitis
0.000 0.316 0.684
L24 Irritant contact dermatitis
0.000 0.316 0.684
L26 Exfoliative dermatitis
0.000 0.316 0.684
L22 Diaper [napkin] dermatitis
0.000 0.316 0.684
E20-E35 Disorders of other endocrine glands
0.000 0.317 0.683
L20 Atopic dermatitis
0.000 0.319 0.681
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.321 0.679
M07.3 Other psoriatic arthropathies
0.000 0.325 0.675
E27 Other disorders of adrenal gland
0.000 0.326 0.674
M06.4 Inflammatory polyarthropathy
0.000 0.328 0.672
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.329 0.671
L27.8 Dermatitis due to other substances taken internally
0.000 0.329 0.671
L27.2 Dermatitis due to ingested food
0.000 0.329 0.671
L40.8 Other psoriasis
0.000 0.331 0.669
E66.1 Drug-induced obesity
0.000 0.332 0.668
L44 Other papulosquamous disorders
0.000 0.333 0.667
L41 Parapsoriasis
0.000 0.333 0.667
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.333 0.667
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.333 0.667
L50-L54 Urticaria and erythema
0.000 0.337 0.662
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.338 0.662
L58 Radiodermatitis
0.000 0.338 0.662
L55 Sunburn
0.000 0.338 0.662
L10-L14 Bullous disorders
0.000 0.340 0.660
L40.9 Psoriasis, unspecified
0.000 0.340 0.660
L29.9 Pruritus, unspecified
0.000 0.343 0.657
E11.1 With ketoacidosis
0.000 0.344 0.656
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.347 0.653
E27.1 Primary adrenocortical insufficiency
0.000 0.348 0.652
E06.3 Autoimmune thyroiditis
0.000 0.348 0.652
L40.4 Guttate psoriasis
0.000 0.348 0.652
L40.3 Pustulosis palmaris et plantaris
0.000 0.348 0.652
L40.2 Acrodermatitis continua
0.000 0.348 0.652
L40.1 Generalised pustular psoriasis
0.000 0.348 0.652
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.350 0.650
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.351 0.649
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.351 0.649
E11.6 With other specified complications
0.000 0.352 0.648
L01 Impetigo
0.000 0.352 0.648
L00 Staphylococcal scalded skin syndrome
0.000 0.352 0.648
L30.5 Pityriasis alba
0.000 0.352 0.648
L30.4 Erythema intertrigo
0.000 0.352 0.648
L30.3 Infective dermatitis
0.000 0.352 0.648
L30.2 Cutaneous autosensitisation
0.000 0.352 0.648
L30.1 Dyshidrosis [pompholyx]
0.000 0.352 0.648
L30.0 Nummular dermatitis
0.000 0.352 0.648
E14.8 With unspecified complications
0.000 0.352 0.648
E14.7 With multiple complications
0.000 0.352 0.648
E14.6 With other specified complications
0.000 0.352 0.648
E14.5 With peripheral circulatory complications
0.000 0.352 0.648
E14.1 With ketoacidosis
0.000 0.352 0.648
E14.0 With coma
0.000 0.352 0.648
L23 Allergic contact dermatitis
0.000 0.353 0.646
L43.8 Other lichen planus
0.000 0.354 0.645
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.356 0.644
L57.5 Actinic granuloma
0.000 0.356 0.644
L57.3 Poikiloderma of Civatte
0.000 0.356 0.644
L57.2 Cutis rhomboidalis nuchae
0.000 0.356 0.644
L57.1 Actinic reticuloid
0.000 0.356 0.644
M13.0 Polyarthritis, unspecified
0.000 0.357 0.643
L29.3 Anogenital pruritus, unspecified
0.000 0.357 0.643
L29.1 Pruritus scroti
0.000 0.357 0.643
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.367 0.633
L28 Lichen simplex chronicus and prurigo
0.000 0.372 0.628
L42 Pityriasis rosea
0.000 0.373 0.627
L08.1 Erythrasma
0.000 0.375 0.625
L08.0 Pyoderma
0.000 0.375 0.625
E66.0 Obesity due to excess calories
0.000 0.376 0.624
E13 Other specified diabetes mellitus
0.000 0.382 0.618
M35.1 Other overlap syndromes
0.000 0.382 0.618
L83 Acanthosis nigricans
0.000 0.382 0.618
L57.4 Cutis laxa senilis
0.000 0.383 0.617
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.384 0.616
M35.7 Hypermobility syndrome
0.000 0.385 0.615
E40-E46 Malnutrition
0.000 0.387 0.613
E14.4 With neurological complications
0.000 0.392 0.608
L04 Acute lymphadenitis
0.000 0.395 0.605
L29.2 Pruritus vulvae
0.000 0.395 0.605
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.396 0.603
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.397 0.603
M06.38 Rheumatoid nodule (Other)
0.000 0.397 0.603
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.397 0.603
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.397 0.603
M06.33 Rheumatoid nodule (Forearm)
0.000 0.397 0.603
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.397 0.603
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.397 0.603
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.397 0.603
E50-E64 Other nutritional deficiencies
0.000 0.401 0.599
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.401 0.598
M10.9 Gout, unspecified
0.000 0.402 0.598
M14.6 Neuropathic arthropathy
0.000 0.405 0.594
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.408 0.592
M20-M25 Other joint disorders
0.000 0.410 0.590
H36.0 Diabetic retinopathy
0.000 0.414 0.586
M11 Other crystal arthropathies
0.000 0.414 0.586
D64.9 Anaemia, unspecified
0.000 0.415 0.585
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.421 0.579
E20 Hypoparathyroidism
0.000 0.423 0.576
M07.6 Other enteropathic arthropathies
0.000 0.424 0.575
M07.5 Arthropathy in ulcerative colitis
0.000 0.424 0.575
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.424 0.575
M07.2 Psoriatic spondylitis
0.000 0.424 0.575
M07.1 Arthritis mutilans
0.000 0.424 0.575
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.424 0.575
D64 Other anaemias
0.000 0.425 0.575
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.001 0.425 0.574
L43.9 Lichen planus, unspecified
0.000 0.426 0.574
# Top node
0.000 0.427 0.573
D60-D64 Aplastic and other anaemias
0.000 0.431 0.569
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.431 0.569
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.432 0.568
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.433 0.567
L21.8 Other seborrhoeic dermatitis
0.000 0.436 0.564
L21.1 Seborrhoeic infantile dermatitis
0.000 0.436 0.564
L21.0 Seborrhoea capitis
0.000 0.436 0.564
E27.8 Other specified disorders of adrenal gland
0.000 0.436 0.564
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.438 0.562
E06.5 Other chronic thyroiditis
0.000 0.439 0.561
E06.4 Drug-induced thyroiditis
0.000 0.439 0.561
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.439 0.561
E06.1 Subacute thyroiditis
0.000 0.439 0.561
E06.0 Acute thyroiditis
0.000 0.439 0.561
L30.8 Other specified dermatitis
0.000 0.444 0.556
E27.2 Addisonian crisis
0.000 0.444 0.556
L91 Hypertrophic disorders of skin
0.000 0.444 0.556
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.445 0.555
L43.3 Subacute (active) lichen planus
0.000 0.447 0.553
L43.2 Lichenoid drug reaction
0.000 0.447 0.553
L43.1 Bullous lichen planus
0.000 0.447 0.553
L43.0 Hypertrophic lichen planus
0.000 0.447 0.553
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.447 0.553
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.452 0.548
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.455 0.545
L05 Pilonidal cyst
0.000 0.456 0.543
L50 Urticaria
0.000 0.457 0.543
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.000 0.457 0.543
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.458 0.542
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.458 0.542
M14.4 Arthropathy in amyloidosis
0.000 0.458 0.542
M14.3 Lipoid dermatoarthritis
0.000 0.458 0.542
M14.2 Diabetic arthropathy
0.000 0.458 0.542
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.458 0.542
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.458 0.542
L03 Cellulitis
0.000 0.458 0.542
M34 Systemic sclerosis
0.000 0.459 0.541
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.460 0.539
M22 Disorders of patella
0.000 0.463 0.537
E14.2 Withrenal complications
0.000 0.465 0.534
D50-D53 Nutritional anaemias
0.000 0.466 0.534
M10.4 Other secondary gout
0.000 0.470 0.530
M10.3 Gout due to impairment of renal function
0.000 0.470 0.530
M10.2 Drug-induced gout
0.000 0.470 0.530
M10.1 Lead-induced gout
0.000 0.470 0.530
L82 Seborrhoeic keratosis
0.000 0.472 0.528
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.480 0.520
M35.8 Other specified systemic involvement of connective tissue
0.000 0.480 0.520
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.480 0.520
M35.5 Multifocal fibrosclerosis
0.000 0.480 0.520
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.480 0.520
L94 Other localised connective tissue disorders
0.000 0.481 0.519
M31 Other necrotising vasculopathies
0.000 0.483 0.517
E06.9 Thyroiditis, unspecified
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.487 0.513
M06.18 Adult-onset Still's disease (Other)
0.000 0.487 0.513
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.487 0.513
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.487 0.513
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.487 0.513
M06.14 Adult-onset Still's disease (Hand)
0.000 0.487 0.513
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.487 0.513
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.487 0.513
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.487 0.513
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.487 0.513
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.487 0.513
M06.28 Rheumatoid bursitis (Other)
0.000 0.487 0.513
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.487 0.513
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.487 0.513
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.487 0.513
M06.24 Rheumatoid bursitis (Hand)
0.000 0.487 0.513
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.487 0.513
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.487 0.513
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.487 0.513
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.487 0.513
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.487 0.513
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.487 0.513
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.487 0.513
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.488 0.512
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.491 0.508
L87 Transepidermal elimination disorders
0.000 0.491 0.508
L88 Pyoderma gangrenosum
0.000 0.491 0.508
L86 Keratoderma in diseases classified elsewhere
0.000 0.491 0.508
M08.9 Juvenile arthritis, unspecified
0.000 0.496 0.504
M08.8 Other juvenile arthritis
0.000 0.496 0.504
M08.4 Pauciarticular juvenile arthritis
0.000 0.496 0.504
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.496 0.504
M08.2 Juvenile arthritis with systemic onset
0.000 0.496 0.504
M08.1 Juvenile ankylosing spondylitis
0.000 0.496 0.504
M08.0 Juvenile rheumatoid arthritis
0.000 0.496 0.504
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.496 0.504
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.496 0.504
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.496 0.504
M09.0 Juvenile arthritis in psoriasis
0.000 0.496 0.504
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.496 0.504
M12.5 Traumatic arthropathy
0.000 0.496 0.504
M12.4 Intermittent hydrarthrosis
0.000 0.496 0.504
M12.3 Palindromic rheumatism
0.000 0.496 0.504
M12.2 Villonodular synovitis (pigmented)
0.000 0.496 0.504
M12.1 Kaschin-Beck disease
0.000 0.496 0.504
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.496 0.504
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.496 0.504
L56.4 Polymorphous light eruption
0.000 0.496 0.504
L56.3 Solar urticaria
0.000 0.496 0.504
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.496 0.504
L56.1 Drug photoallergic response
0.000 0.496 0.504
L56.0 Drug phototoxic response
0.000 0.496 0.504
M13.8 Other specified arthritis
0.000 0.498 0.502
M13.1 Monoarthritis, not elsewhere classified
0.000 0.498 0.502
E20.9 Hypoparathyroidism, unspecified
0.000 0.500 0.500
M05.09 Felty's syndrome (Site unspecified)
0.000 0.503 0.497
M05.08 Felty's syndrome (Other)
0.000 0.503 0.497
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.503 0.497
M05.06 Felty's syndrome (Lower leg)
0.000 0.503 0.497
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.503 0.497
M05.04 Felty's syndrome (Hand)
0.000 0.503 0.497
M05.03 Felty's syndrome (Forearm)
0.000 0.503 0.497
M05.02 Felty's syndrome (Upper arm)
0.000 0.503 0.497
M05.01 Felty's syndrome (Shoulder region)
0.000 0.503 0.497
M05.00 Felty's syndrome (Multiple sites)
0.000 0.503 0.497
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.503 0.497
M05.18 Rheumatoid lung disease (Other)
0.000 0.503 0.497
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.503 0.497
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.503 0.497
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.503 0.497
M05.14 Rheumatoid lung disease (Hand)
0.000 0.503 0.497
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.503 0.497
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.503 0.497
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.503 0.497
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.503 0.497
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.503 0.497
M05.28 Rheumatoid vasculitis (Other)
0.000 0.503 0.497
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.503 0.497
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.503 0.497
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.503 0.497
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.503 0.497
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.503 0.497
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.503 0.497
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.503 0.497
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.503 0.497
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.503 0.497
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.503 0.497
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.503 0.497
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.503 0.497
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.503 0.497
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.503 0.497
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.503 0.497
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.503 0.497
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.503 0.497
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.503 0.497
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.503 0.497
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.503 0.497
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.503 0.497
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.503 0.497
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.503 0.497
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.503 0.497
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.503 0.497
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.503 0.497
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.503 0.497
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.503 0.497
E07 Other disorders of thyroid
0.000 0.505 0.494
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.505 0.495
M10.90 Gout, unspecified (Multiple sites)
0.000 0.506 0.494
E67.8 Other specified hyperalimentation
0.000 0.507 0.493
E67.3 Hypervitaminosis D
0.000 0.507 0.493
E67.2 Megavitamin-B6 syndrome
0.000 0.507 0.493
E67.1 Hypercarotenaemia
0.000 0.507 0.493
E67.0 Hypervitaminosis A
0.000 0.507 0.493
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.509 0.490
L24.8 Irritant contact dermatitis due to other agents
0.000 0.509 0.490
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.509 0.490
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.509 0.490
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.509 0.490
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.509 0.490
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.509 0.490
L24.2 Irritant contact dermatitis due to solvents
0.000 0.509 0.490
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.509 0.490
L24.0 Irritant contact dermatitis due to detergents
0.000 0.509 0.490
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.509 0.490
L25.8 Unspecified contact dermatitis due to other agents
0.000 0.509 0.490
L25.5 Unspecified contact dermatitis due to plants, except food
0.000 0.509 0.490
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.000 0.509 0.490
L25.3 Unspecified contact dermatitis due to other chemical products
0.000 0.509 0.490
L25.2 Unspecified contact dermatitis due to dyes
0.000 0.509 0.490
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.000 0.509 0.490
L25.0 Unspecified contact dermatitis due to cosmetics
0.000 0.509 0.490
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.510 0.489
E32 Diseases of thymus
0.000 0.510 0.489
E31 Polyglandular dysfunction
0.000 0.510 0.489
E30 Disorders of puberty, not elsewhere classified
0.000 0.510 0.489
L20.8 Other atopic dermatitis
0.000 0.512 0.488
L20.0 Besnier's prurigo
0.000 0.512 0.488
M31.3 Wegener's granulomatosis
0.000 0.512 0.488
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.513 0.487
E15 Nondiabetic hypoglycaemic coma
0.000 0.513 0.487
M22.2 Patellofemoral disorders
0.000 0.514 0.486
L50.0 Allergic urticaria
0.000 0.514 0.486
M10.0 Idiopathic gout
0.000 0.514 0.485
L20.9 Atopic dermatitis, unspecified
0.000 0.515 0.485
M07.38 Other psoriatic arthropathies (Other)
0.000 0.516 0.484
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.516 0.484
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.516 0.484
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.516 0.484
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.516 0.484
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.516 0.484
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.516 0.484
E27.5 Adrenomedullary hyperfunction
0.000 0.516 0.483
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.516 0.483
E27.0 Other adrenocortical overactivity
0.000 0.516 0.483
L93 Lupus erythematosus
0.000 0.517 0.483
D61 Other aplastic anaemias
0.000 0.518 0.482
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.518 0.482
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.518 0.482
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.518 0.482
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.518 0.482
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.518 0.482
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.518 0.482
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.518 0.482
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.518 0.482
M10.96 Gout, unspecified (Lower leg)
0.000 0.519 0.481
D51 Vitamin B12 deficiency anaemia
0.000 0.519 0.481
L80 Vitiligo
0.000 0.520 0.479
L41.9 Parapsoriasis, unspecified
0.000 0.521 0.478
L41.8 Other parapsoriasis
0.000 0.521 0.478
L41.5 Retiform parapsoriasis
0.000 0.521 0.478
L41.4 Large plaque parapsoriasis
0.000 0.521 0.478
L41.3 Small plaque parapsoriasis
0.000 0.521 0.478
L41.2 Lymphomatoid papulosis
0.000 0.521 0.478
L41.1 Pityriasis lichenoides chronica
0.000 0.521 0.478
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.521 0.478
L44.9 Papulosquamous disorder, unspecified
0.000 0.521 0.478
L44.8 Other specified papulosquamous disorders
0.000 0.521 0.478
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.521 0.478
L44.3 Lichen ruber moniliformis
0.000 0.521 0.478
L44.2 Lichen striatus
0.000 0.521 0.478

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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