TreeWAS – Variant ID: rs4455661

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.592	0.408
E10.9 Without complications	0.000	0.597	0.403
E10.4 With neurological complications	0.000	0.619	0.381
E10.5 With peripheral circulatory complications	0.000	0.625	0.375
E10.6 With other specified complications	0.000	0.632	0.368
E10.8 With unspecified complications	0.000	0.656	0.344
E10-E14 Diabetes mellitus	0.000	0.688	0.312
E10.1 With ketoacidosis	0.000	0.693	0.307
E10.2 With renal complications	0.000	0.695	0.305
E10.7 With multiple complications	0.000	0.708	0.292
E83 Disorders of mineral metabolism	0.000	0.720	0.280
K90 Intestinal malabsorption	0.000	0.721	0.278
E10.0 With coma	0.000	0.724	0.276
E13 Other specified diabetes mellitus	0.000	0.736	0.264
E10.3 With ophthalmic complications	0.000	0.740	0.260
E14 Unspecified diabetes mellitus	0.000	0.761	0.239
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.765	0.235
E13.9 Without complications	0.000	0.768	0.232
E70-E90 Metabolic disorders	0.000	0.768	0.232
E14.3 With ophthalmic complications	0.000	0.771	0.229
E12 Malnutrition-related diabetes mellitus	0.000	0.776	0.224
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.777	0.223
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.797	0.203
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.799	0.201
E83.8 Other disorders of mineral metabolism	0.000	0.799	0.201
E83.2 Disorders of zinc metabolism	0.000	0.799	0.201
E83.0 Disorders of copper metabolism	0.000	0.799	0.201
K90.3 Pancreatic steatorrhoea	0.000	0.800	0.200
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.800	0.200
K90.1 Tropical sprue	0.000	0.800	0.200
E40-E46 Malnutrition	0.000	0.802	0.197
E88 Other metabolic disorders	0.000	0.805	0.195
K90.8 Other intestinal malabsorption	0.000	0.808	0.192
E13.8 With unspecified complications	0.000	0.810	0.190
E13.7 With multiple complications	0.000	0.810	0.190
E13.6 With other specified complications	0.000	0.810	0.190
E13.5 With peripheral circulatory complications	0.000	0.810	0.190
E13.4 With neurological complications	0.000	0.810	0.190
E13.2 With renal complications	0.000	0.810	0.190
E13.1 With ketoacidosis	0.000	0.810	0.190
E13.0 With coma	0.000	0.810	0.190
E85 Amyloidosis	0.000	0.811	0.189
E13.3 With ophthalmic complications	0.000	0.815	0.185
E16 Other disorders of pancreatic internal secretion	0.000	0.820	0.180
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.822	0.178
E14.5 With peripheral circulatory complications	0.000	0.822	0.178
E14.7 With multiple complications	0.000	0.829	0.171
E14.6 With other specified complications	0.000	0.829	0.171
E14.2 Withrenal complications	0.000	0.829	0.171
E14.0 With coma	0.000	0.829	0.171
E46 Unspecified protein-energy malnutrition	0.000	0.829	0.171
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.830	0.170
E16.2 Hypoglycaemia, unspecified	0.000	0.831	0.169
E84 Cystic fibrosis	0.000	0.833	0.167
E77 Disorders of glycoprotein metabolism	0.000	0.833	0.167
E76 Disorders of glycosaminoglycan metabolism	0.000	0.833	0.167
E72 Other disorders of amino-acid metabolism	0.000	0.833	0.167
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.833	0.167
E70 Disorders of aromatic amino-acid metabolism	0.000	0.833	0.167
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.833	0.167
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.834	0.166
E14.4 With neurological complications	0.000	0.835	0.165
E65-E68 Obesity and other hyperalimentation	0.000	0.839	0.161
E12.9 Without complications	0.000	0.839	0.160
E12.8 With unspecified complications	0.000	0.839	0.160
E12.7 With multiple complications	0.000	0.839	0.160
E12.6 With other specified complications	0.000	0.839	0.160
E12.5 With peripheral circulatory complications	0.000	0.839	0.160
E12.4 With neurological complications	0.000	0.839	0.160
E12.3 With ophthalmic complications	0.000	0.839	0.160
E12.2 With renal complications	0.000	0.839	0.160
E12.1 With ketoacidosis	0.000	0.839	0.160
E12.0 With coma	0.000	0.839	0.160
E85.9 Amyloidosis, unspecified	0.000	0.842	0.158
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.842	0.158
E79 Disorders of purine and pyrimidine metabolism	0.000	0.849	0.151
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.851	0.149
E88.8 Other specified metabolic disorders	0.000	0.852	0.148
E88.2 Lipomatosis, not elsewhere classified	0.000	0.853	0.147
E15 Nondiabetic hypoglycaemic coma	0.000	0.854	0.146
E14.1 With ketoacidosis	0.000	0.854	0.145
E89.2 Postprocedural hypoparathyroidism	0.000	0.856	0.144
E85.4 Organ-limited amyloidosis	0.000	0.857	0.143
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.858	0.142
E45 Retarded development following protein-energy malnutrition	0.000	0.858	0.142
E43 Unspecified severe protein-energy malnutrition	0.000	0.858	0.142
E42 Marasmic kwashiorkor	0.000	0.858	0.142
E41 Nutritional marasmus	0.000	0.858	0.142
E40 Kwashiorkor	0.000	0.858	0.142
E14.8 With unspecified complications	0.000	0.858	0.142
E88.3 Tumour lysis syndrome	0.000	0.859	0.141
E89.0 Postprocedural hypothyroidism	0.000	0.861	0.139
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.862	0.138
E65 Localised adiposity	0.000	0.862	0.138
E85.8 Other amyloidosis	0.000	0.865	0.135
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.865	0.135
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.865	0.135
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.865	0.135
E11 Non-insulin-dependent diabetes mellitus	0.000	0.866	0.134
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.866	0.134
E89.4 Postprocedural ovarian failure	0.000	0.866	0.133
E74 Other disorders of carbohydrate metabolism	0.000	0.868	0.132
E88.9 Metabolic disorder, unspecified	0.000	0.870	0.130
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.871	0.129
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.871	0.129
E16.4 Abnormal secretion of gastrin	0.000	0.871	0.129
E16.3 Increased secretion of glucagon	0.000	0.871	0.129
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.872	0.128
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.872	0.128
E89.5 Postprocedural testicular hypofunction	0.000	0.872	0.128
E89.1 Postprocedural hypoinsulinaemia	0.000	0.872	0.128
E80.4 Gilbert's syndrome	0.000	0.873	0.127
E85.3 Secondary systemic amyloidosis	0.000	0.874	0.126
E75.5 Other lipid storage disorders	0.000	0.874	0.126
E75.6 Lipid storage disorder, unspecified	0.000	0.878	0.122
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.878	0.122
E75.3 Sphingolipidosis, unspecified	0.000	0.878	0.122
E75.2 Other sphingolipidosis	0.000	0.878	0.122
E75.1 Other gangliosidosis	0.000	0.878	0.122
E75.0 GM2 gangliosidosis	0.000	0.878	0.122
E83.3 Disorders of phosphorus metabolism	0.000	0.879	0.121
E73 Lactose intolerance	0.001	0.879	0.120
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.880	0.120
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.880	0.120
E70.3 Albinism	0.000	0.880	0.120
E70.2 Disorders of tyrosine metabolism	0.000	0.880	0.120
E70.1 Other hyperphenylalaninaemias	0.000	0.880	0.120
E70.0 Classical phenylketonuria	0.000	0.880	0.120
E71.3 Disorders of fatty-acid metabolism	0.000	0.880	0.120
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.880	0.120
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.880	0.120
E71.0 Maple-syrup-urine disease	0.000	0.880	0.120
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.880	0.120
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.880	0.120
E72.5 Disorders of glycine metabolism	0.000	0.880	0.120
E72.4 Disorders of ornithine metabolism	0.000	0.880	0.120
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.880	0.120
E72.2 Disorders of urea cycle metabolism	0.000	0.880	0.120
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.880	0.120
E72.0 Disorders of amino-acid transport	0.000	0.880	0.120
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.880	0.120
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.880	0.120
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.880	0.120
E76.2 Other mucopolysaccharidoses	0.000	0.880	0.120
E76.1 Mucopolysaccharidosis, type II	0.000	0.880	0.120
E76.0 Mucopolysaccharidosis, type I	0.000	0.880	0.120
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.880	0.120
E77.8 Other disorders of glycoprotein metabolism	0.000	0.880	0.120
E77.1 Defects in glycoprotein degradation	0.000	0.880	0.120
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.880	0.120
E84.9 Cystic fibrosis, unspecified	0.000	0.880	0.120
E84.8 Cystic fibrosis with other manifestations	0.000	0.880	0.120
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.880	0.120
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.880	0.120
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.881	0.119
E80.5 Crigler-Najjar syndrome	0.000	0.881	0.119
E80.3 Defects of catalase and peroxydase	0.000	0.881	0.119
E80.1 Porphyria cutanea tarda	0.000	0.881	0.119
E80.0 Hereditary erythropoietic porphyria	0.000	0.881	0.119
E83.4 Disorders of magnesium metabolism	0.000	0.883	0.117
E00-E07 Disorders of thyroid gland	0.000	0.884	0.116
E67 Other hyperalimentation	0.000	0.884	0.115
E68 Sequelae of hyperalimentation	0.000	0.884	0.115
E80.2 Other porphyria	0.000	0.885	0.115
E80.6 Other disorders of bilirubin metabolism	0.000	0.886	0.114
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.891	0.108
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.891	0.108
E79.1 Lesch-Nyhan syndrome	0.000	0.891	0.108
E11.5 With peripheral circulatory complications	0.000	0.891	0.109
E11.0 With coma	0.000	0.897	0.103
E44.1 Mild protein-energy malnutrition	0.000	0.898	0.102
E44.0 Moderate protein-energy malnutrition	0.000	0.898	0.102
E16.1 Other hypoglycaemia	0.000	0.899	0.101
E11.1 With ketoacidosis	0.000	0.899	0.101
E11.8 With unspecified complications	0.000	0.899	0.101
E11.7 With multiple complications	0.000	0.903	0.096
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.905	0.095
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.905	0.095
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.905	0.095
E74.2 Disorders of galactose metabolism	0.000	0.905	0.095
E74.1 Disorders of fructose metabolism	0.000	0.905	0.095
E11.2 With renal complications	0.000	0.906	0.094
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.907	0.093
E04 Other non-toxic goitre	0.000	0.907	0.093
E11.6 With other specified complications	0.000	0.907	0.093
E11.4 With neurological complications	0.000	0.909	0.091
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.910	0.090
E07 Other disorders of thyroid	0.000	0.911	0.089
E74.0 Glycogen storage disease	0.000	0.913	0.087
E73.8 Other lactose intolerance	0.001	0.913	0.086
E73.1 Secondary lactase deficiency	0.001	0.913	0.086
E73.0 Congenital lactase deficiency	0.001	0.913	0.086
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.913	0.087
E04.9 Non-toxic goitre, unspecified	0.000	0.916	0.084
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.917	0.083
E00 Congenital iodine-deficiency syndrome	0.000	0.917	0.083
E67.8 Other specified hyperalimentation	0.000	0.917	0.083
E67.3 Hypervitaminosis D	0.000	0.917	0.083
E67.2 Megavitamin-B6 syndrome	0.000	0.917	0.083
E67.1 Hypercarotenaemia	0.000	0.917	0.083
E67.0 Hypervitaminosis A	0.000	0.917	0.083
E50-E64 Other nutritional deficiencies	0.000	0.918	0.081
E06 Thyroiditis	0.000	0.921	0.079
E89.3 Postprocedural hypopituitarism	0.000	0.922	0.078
K90.9 Intestinal malabsorption, unspecified	0.001	0.923	0.076
E03 Other hypothyroidism	0.000	0.924	0.076
E07.9 Disorder of thyroid, unspecified	0.000	0.926	0.074
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.927	0.073
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.928	0.072
E11.3 With ophthalmic complications	0.000	0.929	0.071
E78.4 Other hyperlipidaemia	0.000	0.929	0.071
E04.0 Non-toxic diffuse goitre	0.000	0.930	0.070
E83.5 Disorders of calcium metabolism	0.000	0.930	0.070
E03.8 Other specified hypothyroidism	0.000	0.931	0.068
E78.6 Lipoprotein deficiency	0.000	0.932	0.068
E20-E35 Disorders of other endocrine glands	0.000	0.933	0.067
E04.8 Other specified non-toxic goitre	0.000	0.933	0.067
E87.3 Alkalosis	0.000	0.933	0.067
E78.3 Hyperchylomicronaemia	0.000	0.935	0.064
E07.1 Dyshormogenetic goitre	0.000	0.936	0.064
E07.0 Hypersecretion of calcitonin	0.000	0.936	0.064
E14.9 Without complications	0.000	0.936	0.064
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.936	0.063
E04.2 Non-toxic multinodular goitre	0.000	0.937	0.063
E78.1 Pure hyperglyceridaemia	0.000	0.939	0.061
E87.0 Hyperosmolality and hypernatraemia	0.000	0.939	0.061
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.940	0.060
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.940	0.060
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.940	0.060
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.940	0.060
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.940	0.060
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.940	0.060
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.940	0.060
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.940	0.060
E06.3 Autoimmune thyroiditis	0.000	0.941	0.059
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.941	0.058
E63 Other nutritional deficiencies	0.000	0.941	0.058
E56 Other vitamin deficiencies	0.000	0.941	0.058
E50 Vitamin A deficiency	0.000	0.941	0.058
E60 Dietary zinc deficiency	0.000	0.941	0.058
E59 Dietary selenium deficiency	0.000	0.941	0.058
E54 Ascorbic acid deficiency	0.000	0.941	0.058
E52 Niacin deficiency [pellagra]	0.000	0.941	0.058
E58 Dietary calcium deficiency	0.000	0.942	0.058
E66 Obesity	0.000	0.942	0.058
E06.5 Other chronic thyroiditis	0.000	0.943	0.057
E06.4 Drug-induced thyroiditis	0.000	0.943	0.057
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.943	0.057
E06.1 Subacute thyroiditis	0.000	0.943	0.057
E06.0 Acute thyroiditis	0.000	0.943	0.057
E78.2 Mixed hyperlipidaemia	0.000	0.943	0.057
E07.8 Other specified disorders of thyroid	0.000	0.943	0.056
E03.5 Myxoedema coma	0.000	0.945	0.055
E03.4 Atrophy of thyroid (acquired)	0.000	0.945	0.055
E03.3 Postinfectious hypothyroidism	0.000	0.945	0.055
E03.1 Congenital hypothyroidism without goitre	0.000	0.945	0.055
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.945	0.055
E51 Thiamine deficiency	0.000	0.946	0.054
E53 Deficiency of other B group vitamins	0.000	0.946	0.054
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.946	0.053
E87.7 Fluid overload	0.000	0.947	0.053
E87.4 Mixed disorder of acid-base balance	0.000	0.948	0.052
E87.2 Acidosis	0.000	0.948	0.052
E20 Hypoparathyroidism	0.000	0.949	0.051
E26 Hyperaldosteronism	0.000	0.949	0.051
E06.9 Thyroiditis, unspecified	0.000	0.950	0.050
E28 Ovarian dysfunction	0.000	0.951	0.049
E29 Testicular dysfunction	0.000	0.951	0.049
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.951	0.049
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.951	0.048
E32 Diseases of thymus	0.000	0.951	0.048
E31 Polyglandular dysfunction	0.000	0.951	0.048
E30 Disorders of puberty, not elsewhere classified	0.000	0.951	0.048
E25 Adrenogenital disorders	0.000	0.951	0.048
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.952	0.048
E55 Vitamin D deficiency	0.000	0.952	0.048
E23 Hypofunction and other disorders of pituitary gland	0.000	0.952	0.048
E04.1 Non-toxic single thyroid nodule	0.000	0.952	0.048
E23.2 Diabetes insipidus	0.000	0.956	0.044
E34 Other endocrine disorders	0.000	0.956	0.044
E24 Cushing's syndrome	0.000	0.956	0.044
E50.9 Vitamin A deficiency, unspecified	0.000	0.958	0.042
E50.8 Other manifestations of vitamin A deficiency	0.000	0.958	0.042
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.958	0.042
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.958	0.042
E50.5 Vitamin A deficiency with night blindness	0.000	0.958	0.042
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.958	0.042
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.958	0.042
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.958	0.042
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.958	0.042
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.958	0.042
E56.9 Vitamin deficiency, unspecified	0.000	0.958	0.042
E56.8 Deficiency of other vitamins	0.000	0.958	0.042
E56.1 Deficiency of vitamin K	0.000	0.958	0.042
E56.0 Deficiency of vitamin E	0.000	0.958	0.042
E63.9 Nutritional deficiency, unspecified	0.000	0.958	0.042
E63.8 Other specified nutritional deficiencies	0.000	0.958	0.042
E63.1 Imbalance of constituents of food intake	0.000	0.958	0.042
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.958	0.042
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.958	0.042
E64.8 Sequelae of other nutritional deficiencies	0.000	0.958	0.042
E64.3 Sequelae of rickets	0.000	0.958	0.042
E64.2 Sequelae of vitamin C deficiency	0.000	0.958	0.042
E64.1 Sequelae of vitamin A deficiency	0.000	0.958	0.042
E64.0 Sequelae of protein-energy malnutrition	0.000	0.958	0.042
E28.2 Polycystic ovarian syndrome	0.000	0.958	0.042
E87.5 Hyperkalaemia	0.000	0.958	0.042
E66.1 Drug-induced obesity	0.000	0.958	0.041
E27 Other disorders of adrenal gland	0.000	0.959	0.041
E73.9 Lactose intolerance, unspecified	0.001	0.959	0.040
E66.0 Obesity due to excess calories	0.000	0.960	0.040
E20.9 Hypoparathyroidism, unspecified	0.000	0.960	0.040
E51.9 Thiamine deficiency, unspecified	0.000	0.961	0.039
E51.8 Other manifestations of thiamine deficiency	0.000	0.961	0.039
E51.1 Beriberi	0.000	0.961	0.039
E26.0 Primary hyperaldosteronism	0.000	0.961	0.039
E53.1 Pyridoxine deficiency	0.000	0.961	0.039
E53.0 Riboflavin deficiency	0.000	0.961	0.039
E78.8 Other disorders of lipoprotein metabolism	0.000	0.961	0.038
E27.1 Primary adrenocortical insufficiency	0.000	0.961	0.039
E53.9 Vitamin B deficiency, unspecified	0.000	0.962	0.038
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.962	0.038
E20.8 Other hypoparathyroidism	0.000	0.963	0.037
E20.1 Pseudohypoparathyroidism	0.000	0.963	0.037
E20.0 Idiopathic hypoparathyroidism	0.000	0.963	0.037
E24.2 Drug-induced Cushing's syndrome	0.000	0.963	0.037
E26.9 Hyperaldosteronism, unspecified	0.000	0.963	0.036
E26.8 Other hyperaldosteronism	0.000	0.963	0.036
E26.1 Secondary hyperaldosteronism	0.000	0.963	0.036
E05.8 Other thyrotoxicosis	0.000	0.964	0.036
E29.1 Testicular hypofunction	0.000	0.965	0.035
E28.9 Ovarian dysfunction, unspecified	0.000	0.965	0.035
E28.8 Other ovarian dysfunction	0.000	0.965	0.035
E28.1 Androgen excess	0.000	0.965	0.035
E28.0 Oestrogen excess	0.000	0.965	0.035
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.965	0.035
E29.9 Testicular dysfunction, unspecified	0.000	0.965	0.035
E29.8 Other testicular dysfunction	0.000	0.965	0.035
E29.0 Testicular hyperfunction	0.000	0.965	0.035
E05.5 Thyroid crisis or storm	0.000	0.965	0.035
E05.4 Thyrotoxicosis factitia	0.000	0.965	0.035
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.965	0.035
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.965	0.035
E25.9 Adrenogenital disorder, unspecified	0.000	0.965	0.035
E25.8 Other adrenogenital disorders	0.000	0.965	0.035
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.965	0.035
E30.9 Disorder of puberty, unspecified	0.000	0.965	0.035
E30.8 Other disorders of puberty	0.000	0.965	0.035
E30.1 Precocious puberty	0.000	0.965	0.035
E30.0 Delayed puberty	0.000	0.965	0.035
E31.9 Polyglandular dysfunction, unspecified	0.000	0.965	0.035
E31.8 Other polyglandular dysfunction	0.000	0.965	0.035
E31.1 Polyglandular hyperfunction	0.000	0.965	0.035
E31.0 Autoimmune polyglandular failure	0.000	0.965	0.035
E32.9 Disease of thymus, unspecified	0.000	0.965	0.035
E32.8 Other diseases of thymus	0.000	0.965	0.035
E32.1 Abscess of thymus	0.000	0.965	0.035
E32.0 Persistent hyperplasia of thymus	0.000	0.965	0.035
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.965	0.035
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.965	0.035
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.965	0.035
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.965	0.035
E23.1 Drug-induced hypopituitarism	0.000	0.965	0.035
E55.0 Rickets, active	0.000	0.965	0.035
E51.2 Wernicke's encephalopathy	0.000	0.965	0.034
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.965	0.035
E23.7 Disorder of pituitary gland, unspecified	0.000	0.966	0.034
E53.8 Deficiency of other specified B group vitamins	0.000	0.966	0.034
E34.5 Androgen resistance syndrome	0.000	0.968	0.032
E34.4 Constitutional tall stature	0.000	0.968	0.032
E34.3 Short stature, not elsewhere classified	0.000	0.968	0.032
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.968	0.032
E34.1 Other hypersecretion of intestinal hormones	0.000	0.968	0.032
E24.8 Other Cushing's syndrome	0.000	0.968	0.032
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.968	0.032
E24.3 Ectopic ACTH syndrome	0.000	0.968	0.032
E24.1 Nelson's syndrome	0.000	0.968	0.032
E34.9 Endocrine disorder, unspecified	0.000	0.968	0.032
E34.8 Other specified endocrine disorders	0.000	0.969	0.031
E61 Deficiency of other nutrient elements	0.001	0.969	0.030
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.969	0.031
E23.6 Other disorders of pituitary gland	0.000	0.969	0.030
E27.5 Adrenomedullary hyperfunction	0.000	0.970	0.030
E27.0 Other adrenocortical overactivity	0.000	0.970	0.030
R31 Unspecified haematuria	0.030	0.970	0.000
E34.0 Carcinoid syndrome	0.000	0.971	0.029
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.971	0.029
E24.0 Pituitary-dependent Cushing's disease	0.000	0.971	0.028
E21.3 Hyperparathyroidism, unspecified	0.000	0.973	0.027
E21.4 Other specified disorders of parathyroid gland	0.000	0.975	0.025
E21.2 Other hyperparathyroidism	0.000	0.975	0.025
E55.9 Vitamin D deficiency, unspecified	0.000	0.976	0.024
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.976	0.024
E27.2 Addisonian crisis	0.000	0.977	0.023
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.977	0.023
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.977	0.023
E24.9 Cushing's syndrome, unspecified	0.000	0.977	0.022
E28.3 Primary ovarian failure	0.000	0.977	0.022
E86 Volume depletion	0.000	0.977	0.023
E61.9 Deficiency of nutrient element, unspecified	0.001	0.977	0.022
E61.8 Deficiency of other specified nutrient elements	0.001	0.977	0.022
E61.7 Deficiency of multiple nutrient elements	0.001	0.977	0.022
E61.6 Vanadium deficiency	0.001	0.977	0.022
E61.5 Molybdenum deficiency	0.001	0.977	0.022
E61.4 Chromium deficiency	0.001	0.977	0.022
E61.3 Manganese deficiency	0.001	0.977	0.022
E61.0 Copper deficiency	0.001	0.977	0.022
E22 Hyperfunction of pituitary gland	0.000	0.979	0.021
E66.9 Obesity, unspecified	0.000	0.980	0.020
E27.8 Other specified disorders of adrenal gland	0.000	0.980	0.019
E61.2 Magnesium deficiency	0.001	0.982	0.017
E27.9 Disorder of adrenal gland, unspecified	0.000	0.982	0.017
K90-K93 Other diseases of the digestive system	0.000	0.983	0.017
E23.0 Hypopituitarism	0.000	0.983	0.017
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.984	0.015
E22.8 Other hyperfunction of pituitary gland	0.000	0.984	0.015
E21.0 Primary hyperparathyroidism	0.000	0.985	0.015
E22.1 Hyperprolactinaemia	0.000	0.986	0.014
C71.2 Temporal lobe	0.013	0.987	0.000
C71 Malignant neoplasm of brain	0.013	0.987	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.987	0.013
C71.9 Brain, unspecified	0.013	0.987	0.000
M41.9 Scoliosis, unspecified	0.011	0.989	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.011	0.989	0.000
C71.3 Parietal lobe	0.011	0.989	0.000
C71.1 Frontal lobe	0.011	0.989	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.010	0.990	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.010	0.990	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.010	0.990	0.000
E22.0 Acromegaly and pituitary gigantism	0.001	0.990	0.010
E05.9 Thyrotoxicosis, unspecified	0.000	0.990	0.010
C71.7 Brain stem	0.010	0.990	0.000
C71.6 Cerebellum	0.009	0.990	0.000
C71.5 Cerebral ventricle	0.009	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.009	0.991	0.000
G44.2 Tension-type headache	0.009	0.991	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.991	0.009
K93.1 Megacolon in Chagas' disease	0.000	0.991	0.009
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.991	0.009
C71.8 Overlapping lesion of brain	0.009	0.991	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.991	0.009
E87.6 Hypokalaemia	0.000	0.991	0.009
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.008	0.992	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.008	0.992	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.008	0.992	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.008	0.992	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.992	0.008
C71.4 Occipital lobe	0.008	0.992	0.000
E61.1 Iron deficiency	0.001	0.992	0.007
E66.8 Other obesity	0.000	0.992	0.008
G31.0 Circumscribed brain atrophy	0.000	0.992	0.008
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.992	0.007
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.007	0.993	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.007	0.993	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
N04.9 Unspecified	0.000	0.993	0.007
C69 Malignant neoplasm of eye and adnexa	0.006	0.993	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.007	0.993	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.006	0.994	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.994	0.006
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
C69.9 Eye, unspecified	0.006	0.994	0.000
M79.10 Myalgia (Multiple sites)	0.005	0.994	0.000
M41 Scoliosis	0.005	0.994	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.995	0.000
C69.3 Choroid	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.995	0.005
G44 Other headache syndromes	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
G30 Alzheimer's disease	0.000	0.995	0.005
C70.9 Meninges, unspecified	0.004	0.995	0.000
C70.1 Spinal meninges	0.004	0.995	0.000
G44.8 Other specified headache syndromes	0.004	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
M41.5 Other secondary scoliosis	0.004	0.996	0.000
M41.4 Neuromuscular scoliosis	0.004	0.996	0.000
M41.3 Thoracogenic scoliosis	0.004	0.996	0.000
M41.2 Other idiopathic scoliosis	0.004	0.996	0.000
M41.1 Juvenile idiopathic scoliosis	0.004	0.996	0.000
M41.0 Infantile idiopathic scoliosis	0.004	0.996	0.000
R52.1 Chronic intractable pain	0.004	0.996	0.000
C72.9 Central nervous system, unspecified	0.004	0.996	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.996	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.996	0.000
C72.4 Acoustic nerve	0.004	0.996	0.000
C72.3 Optic nerve	0.004	0.996	0.000
C72.2 Olfactory nerve	0.004	0.996	0.000
C72.1 Cauda equina	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations