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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4461039
log Bayes Factor = 19.9477
Chromosome 15   position 78,817,447  (GRCh37) Explore rs4461039 on Ensembl!
Variant rs4461039 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.004 0.996
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.004 0.996
J90-J94 Other diseases of pleura
0.000 0.006 0.994
I73 Other peripheral vascular diseases
0.000 0.007 0.993
I70 Atherosclerosis
0.000 0.008 0.992
J92 Pleural plaque
0.000 0.010 0.990
I60-I69 Cerebrovascular diseases
0.000 0.013 0.987
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.013 0.987
Chapter IX Diseases of the circulatory system
0.000 0.015 0.985
I73.9 Peripheral vascular disease, unspecified
0.000 0.016 0.984
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.018 0.982
J42 Unspecified chronic bronchitis
0.000 0.019 0.981
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.022 0.978
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.026 0.974
J92.0 Pleural plaque with presence of asbestos
0.000 0.026 0.974
I60 Subarachnoid haemorrhage
0.000 0.029 0.971
J60-J70 Lung diseases due to external agents
0.000 0.031 0.969
I67 Other cerebrovascular diseases
0.000 0.039 0.961
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.039 0.961
J95-J99 Other diseases of the respiratory system
0.000 0.042 0.958
I69 Sequelae of cerebrovascular disease
0.000 0.048 0.952
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.053 0.947
I26 Pulmonary embolism
0.000 0.056 0.944
J92.9 Pleural plaque without asbestos
0.000 0.060 0.940
I77 Other disorders of arteries and arterioles
0.000 0.067 0.933
I27 Other pulmonary heart diseases
0.000 0.067 0.933
J98 Other respiratory disorders
0.000 0.067 0.933
J90 Pleural effusion, not elsewhere classified
0.000 0.077 0.923
J98.1 Pulmonary collapse
0.000 0.077 0.923
I27.9 Pulmonary heart disease, unspecified
0.000 0.087 0.913
I67.9 Cerebrovascular disease, unspecified
0.000 0.088 0.912
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.092 0.908
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.094 0.906
I69.3 Sequelae of cerebral infarction
0.000 0.105 0.895
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.105 0.895
I73.0 Raynaud's syndrome
0.000 0.121 0.879
I72 Other aneurysm
0.000 0.124 0.876
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.131 0.869
J86 Pyothorax
0.000 0.143 0.857
I60.8 Other subarachnoid haemorrhage
0.000 0.147 0.853
I67.8 Other specified cerebrovascular diseases
0.000 0.149 0.851
I77.1 Stricture of artery
0.000 0.157 0.843
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.160 0.840
I67.1 Cerebral aneurysm, nonruptured
0.000 0.164 0.836
J43.2 Centrilobular emphysema
0.000 0.167 0.833
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.168 0.832
J93 Pneumothorax
0.000 0.171 0.829
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.174 0.826
J86.9 Pyothorax without fistula
0.000 0.175 0.825
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.175 0.825
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.176 0.824
J98.4 Other disorders of lung
0.000 0.179 0.821
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.186 0.814
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.190 0.810
I77.0 Arteriovenous fistula, acquired
0.000 0.195 0.805
I72.0 Aneurysm of carotid artery
0.000 0.201 0.799
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.209 0.791
I71.0 Dissection of aorta [any part]
0.000 0.213 0.787
I70.0 Atherosclerosis of aorta
0.000 0.232 0.768
J60 Coalworker's pneumoconiosis
0.000 0.233 0.767
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.234 0.766
J93.1 Other spontaneous pneumothorax
0.000 0.235 0.765
I61 Intracerebral haemorrhage
0.000 0.239 0.761
J98.9 Respiratory disorder, unspecified
0.000 0.244 0.756
J64 Unspecified pneumoconiosis
0.000 0.250 0.750
I72.8 Aneurysm of other specified arteries
0.000 0.268 0.732
I77.2 Rupture of artery
0.000 0.270 0.730
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.275 0.725
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.277 0.723
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I28 Other diseases of pulmonary vessels
0.000 0.287 0.713
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.288 0.712
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I78 Diseases of capillaries
0.000 0.290 0.710
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.292 0.708
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.297 0.703
I00-I02 Acute rheumatic fever
0.000 0.297 0.703
J69 Pneumonitis due to solids and liquids
0.000 0.301 0.699
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.302 0.698
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.304 0.696
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.304 0.696
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.305 0.695
J66 Airway disease due to specific organic dust
0.000 0.305 0.695
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.305 0.695
J62 Pneumoconiosis due to dust containing silica
0.000 0.305 0.695
J65 Pneumoconiosis associated with tuberculosis
0.000 0.305 0.695
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.311 0.689
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.311 0.689
I67.5 Moyamoya disease
0.000 0.311 0.689
I67.4 Hypertensive encephalopathy
0.000 0.311 0.689
I67.3 Progressive vascular leukoencephalopathy
0.000 0.311 0.689
I27.8 Other specified pulmonary heart diseases
0.000 0.312 0.688
J96 Respiratory failure, not elsewhere classified
0.000 0.313 0.687
J98.2 Interstitial emphysema
0.000 0.318 0.682
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.322 0.678
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.326 0.674
I72.9 Aneurysm of unspecified site
0.000 0.327 0.672
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.328 0.672
I77.5 Necrosis of artery
0.000 0.331 0.669
I77.4 Coeliac artery compression syndrome
0.000 0.331 0.669
I27.1 Kyphoscoliotic heart disease
0.000 0.331 0.669
J98.3 Compensatory emphysema
0.000 0.331 0.669
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.332 0.668
I74 Arterial embolism and thrombosis
0.000 0.337 0.663
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.348 0.652
I27.0 Primary pulmonary hypertension
0.000 0.356 0.644
J70 Respiratory conditions due to other external agents
0.000 0.359 0.641
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.372 0.628
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.372 0.628
I72.1 Aneurysm of artery of upper extremity
0.000 0.372 0.628
I73.8 Other specified peripheral vascular diseases
0.000 0.375 0.625
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.376 0.624
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.378 0.622
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.381 0.619
J93.0 Spontaneous tension pneumothorax
0.000 0.383 0.616
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.392 0.608
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.393 0.607
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.403 0.597
I70.1 Atherosclerosis of renal artery
0.000 0.406 0.593
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.409 0.591
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.409 0.591
I79.1 Aortitis in diseases classified elsewhere
0.000 0.409 0.591
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.409 0.591
J85 Abscess of lung and mediastinum
0.000 0.409 0.591
J86.0 Pyothorax with fistula
0.000 0.415 0.585
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.421 0.579
J43.8 Other emphysema
0.000 0.422 0.577
J09-J18 Influenza and pneumonia
0.000 0.430 0.570
J40 Bronchitis, not specified as acute or chronic
0.000 0.430 0.570
I72.3 Aneurysm of iliac artery
0.000 0.432 0.568
I77.8 Other specified disorders of arteries and arterioles
0.000 0.437 0.563
J98.6 Disorders of diaphragm
0.000 0.439 0.561
J94 Other pleural conditions
0.000 0.440 0.560
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.443 0.557
J99.0 Rheumatoid lung disease
0.000 0.443 0.557
I77.3 Arterial fibromuscular dysplasia
0.000 0.449 0.551
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.449 0.551
I67.2 Cerebral atherosclerosis
0.000 0.452 0.548
J93.8 Other pneumothorax
0.000 0.458 0.542
J69.8 Pneumonitis due to other solids and liquids
0.000 0.459 0.541
I72.2 Aneurysm of renal artery
0.000 0.463 0.537
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.471 0.529
I72.4 Aneurysm of artery of lower extremity
0.000 0.472 0.528
I77.6 Arteritis, unspecified
0.000 0.475 0.525
I28.8 Other specified diseases of pulmonary vessels
0.000 0.477 0.522
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.480 0.520
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.483 0.517
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I62 Other nontraumatic intracranial haemorrhage
0.000 0.486 0.514
I05-I09 Chronic rheumatic heart diseases
0.000 0.489 0.511
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.489 0.511
I28.1 Aneurysm of pulmonary artery
0.000 0.489 0.511
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.489 0.511
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.490 0.510
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.491 0.509
I78.9 Disease of capillaries, unspecified
0.000 0.491 0.509
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.492 0.508
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.492 0.508
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.492 0.508
I68.0 Cerebral amyloid angiopathy
0.000 0.492 0.508
J46 Status asthmaticus
0.000 0.494 0.506
I27.2 Other secondary pulmonary hypertension
0.000 0.495 0.505
I02 Rheumatic chorea
0.000 0.496 0.504
I01 Rheumatic fever with heart involvement
0.000 0.496 0.504
J69.1 Pneumonitis due to oils and essences
0.000 0.499 0.501
I00 Rheumatic fever without mention of heart involvement
0.000 0.499 0.501
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.500 0.500
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.502 0.498
J62.0 Pneumoconiosis due to talc dust
0.000 0.502 0.498
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.502 0.498
J63.5 Stannosis
0.000 0.502 0.498
J63.4 Siderosis
0.000 0.502 0.498
J63.3 Graphite fibrosis (of lung)
0.000 0.502 0.498
J63.2 Berylliosis
0.000 0.502 0.498
J63.1 Bauxite fibrosis (of lung)
0.000 0.502 0.498
J63.0 Aluminosis (of lung)
0.000 0.502 0.498
J66.8 Airway disease due to other specific organic dusts
0.000 0.502 0.498
J66.2 Cannabinosis
0.000 0.502 0.498
J66.1 Flax-dresser's disease
0.000 0.502 0.498
J66.0 Byssinosis
0.000 0.502 0.498
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.502 0.498
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.502 0.498
J96.9 Respiratory failure, unspecified
0.000 0.507 0.492
J96.1 Chronic respiratory failure
0.000 0.507 0.492
J96.0 Acute respiratory failure
0.000 0.507 0.492
J95.8 Other postprocedural respiratory disorders
0.000 0.508 0.492
I78.8 Other diseases of capillaries
0.000 0.511 0.489
J18 Pneumonia, organism unspecified
0.000 0.511 0.489
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.512 0.488
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.518 0.482
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.519 0.481
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.521 0.479
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.521 0.479
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.521 0.479
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.521 0.479
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.523 0.477
J18.1 Lobar pneumonia, unspecified
0.000 0.524 0.476
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.524 0.476
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.525 0.475
J91 Pleural effusion in conditions classified elsewhere
0.000 0.527 0.473
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.528 0.472
I74.8 Embolism and thrombosis of other arteries
0.000 0.532 0.468
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.538 0.462
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.540 0.459
J70.8 Respiratory conditions due to other specified external agents
0.000 0.540 0.459
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.540 0.459
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.540 0.459
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.540 0.459
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.540 0.459
J69.0 Pneumonitis due to food and vomit
0.000 0.543 0.457
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.546 0.453
J10 Influenza due to identified influenza virus
0.000 0.552 0.448
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.554 0.446
J67.7 Air-conditioner and humidifier lung
0.000 0.554 0.446
J67.6 Maple-bark-stripper's lung
0.000 0.554 0.446
J67.5 Mushroom-worker's lung
0.000 0.554 0.446
J67.4 Maltworker's lung
0.000 0.554 0.446
J67.3 Suberosis
0.000 0.554 0.446
J67.1 Bagassosis
0.000 0.554 0.446
J67.0 Farmer's lung
0.000 0.554 0.446
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.556 0.444
J95.5 Postprocedural subglottic stenosis
0.000 0.556 0.444
J95.4 Mendelson's syndrome
0.000 0.556 0.444
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.556 0.444
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.556 0.444
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.556 0.444
I74.5 Embolism and thrombosis of iliac artery
0.000 0.558 0.442
J93.9 Pneumothorax, unspecified
0.000 0.561 0.439
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.567 0.433
J98.8 Other specified respiratory disorders
0.000 0.568 0.432
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.573 0.427
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.574 0.425
J85.1 Abscess of lung with pneumonia
0.000 0.575 0.425
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.575 0.424
J85.3 Abscess of mediastinum
0.000 0.576 0.424
J85.0 Gangrene and necrosis of lung
0.000 0.576 0.424
I61.8 Other intracerebral haemorrhage
0.000 0.581 0.419
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.586 0.414
J67.2 Bird fancier's lung
0.000 0.588 0.412
I09 Other rheumatic heart diseases
0.000 0.589 0.411
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.591 0.409
J09 Influenza due to certain identified influenza virus
0.000 0.591 0.409
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.595 0.405
J94.8 Other specified pleural conditions
0.000 0.598 0.402
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.598 0.402
J94.9 Pleural condition, unspecified
0.000 0.598 0.401
J94.0 Chylous effusion
0.000 0.598 0.401
J94.1 Fibrothorax
0.000 0.599 0.401
J20-J22 Other acute lower respiratory infections
0.000 0.599 0.401
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.600 0.400
I07 Rheumatic tricuspid valve diseases
0.000 0.607 0.392
J17 Pneumonia in diseases classified elsewhere
0.000 0.611 0.389
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.613 0.387
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.620 0.379
J95.0 Tracheostomy malfunction
0.000 0.628 0.372
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.628 0.372
J12 Viral pneumonia, not elsewhere classified
0.000 0.634 0.366
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.638 0.361
I01.8 Other acute rheumatic heart disease
0.000 0.638 0.361
I01.2 Acute rheumatic myocarditis
0.000 0.638 0.361
I01.1 Acute rheumatic endocarditis
0.000 0.638 0.361
I01.0 Acute rheumatic pericarditis
0.000 0.638 0.361
I02.9 Rheumatic chorea without heart involvement
0.000 0.638 0.361
I02.0 Rheumatic chorea with heart involvement
0.000 0.638 0.361
J85.2 Abscess of lung without pneumonia
0.000 0.639 0.361
I05 Rheumatic mitral valve diseases
0.000 0.641 0.359
J96.09 Acute respiratory failure; Type unspecified
0.000 0.647 0.353
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.647 0.353
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.647 0.353
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.647 0.353
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.647 0.353
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.647 0.353
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.647 0.353
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.647 0.353
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.647 0.353
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.648 0.352
J18.2 Hypostatic pneumonia, unspecified
0.000 0.649 0.351
J14 Pneumonia due to Haemophilus influenzae
0.000 0.654 0.346
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.654 0.346
I78.1 Naevus, nonneoplastic
0.000 0.660 0.340
I09.9 Rheumatic heart disease, unspecified
0.000 0.661 0.339
I06 Rheumatic aortic valve diseases
0.000 0.661 0.339
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.667 0.333
I62.1 Nontraumatic extradural haemorrhage
0.000 0.669 0.331
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.677 0.323
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.678 0.321
J18.8 Other pneumonia, organism unspecified
0.000 0.681 0.319
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.692 0.308
I07.1 Tricuspid insufficiency
0.000 0.693 0.307
J18.9 Pneumonia, unspecified
0.000 0.693 0.307
I05.1 Rheumatic mitral insufficiency
0.000 0.697 0.303
I09.8 Other specified rheumatic heart diseases
0.000 0.705 0.295
I09.2 Chronic rheumatic pericarditis
0.000 0.705 0.295
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.705 0.295
I09.0 Rheumatic myocarditis
0.000 0.705 0.295
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.706 0.293
J16.0 Chlamydial pneumonia
0.000 0.706 0.293
J15.2 Pneumonia due to staphylococcus
0.000 0.713 0.287
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.713 0.286
J15.8 Other bacterial pneumonia
0.000 0.717 0.283
J21 Acute bronchiolitis
0.000 0.717 0.283
I07.9 Tricuspid valve disease, unspecified
0.000 0.718 0.281
I07.8 Other tricuspid valve diseases
0.000 0.718 0.281
I07.2 Tricuspid stenosis with insufficiency
0.000 0.718 0.281
I07.0 Tricuspid stenosis
0.000 0.718 0.281
J15.5 Pneumonia due to Escherichia coli
0.000 0.720 0.280
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.721 0.279
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.723 0.277
J15.4 Pneumonia due to other streptococci
0.000 0.726 0.274
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.728 0.271
J20 Acute bronchitis
0.000 0.731 0.268
J45 Asthma
0.000 0.732 0.268
J15.3 Pneumonia due to streptococcus, group B
0.000 0.733 0.267
J15.9 Bacterial pneumonia, unspecified
0.000 0.737 0.263
J12.8 Other viral pneumonia
0.000 0.737 0.263
J12.3 Human metapneumovirus pneumonia
0.000 0.737 0.263
J12.2 Parainfluenza virus pneumonia
0.000 0.737 0.263
J12.1 Respiratory syncytial virus pneumonia
0.000 0.737 0.263
J12.0 Adenoviral pneumonia
0.000 0.737 0.263
I05.0 Mitral stenosis
0.000 0.742 0.258
I05.8 Other mitral valve diseases
0.000 0.742 0.257
J00-J06 Acute upper respiratory infections
0.000 0.743 0.257
J11 Influenza, virus not identified
0.001 0.746 0.254
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.751 0.248
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.752 0.248
J94.2 Haemothorax
0.001 0.752 0.247
J84 Other interstitial pulmonary diseases
0.000 0.752 0.247
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.757 0.243
I06.8 Other rheumatic aortic valve diseases
0.000 0.757 0.243
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.757 0.243
I06.1 Rheumatic aortic insufficiency
0.000 0.757 0.243
I63 Cerebral infarction
0.000 0.761 0.239
J17.3 Pneumonia in parasitic diseases
0.000 0.765 0.235
I05.2 Mitral stenosis with insufficiency
0.000 0.766 0.234
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.768 0.231
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.768 0.231
I99 Other and unspecified disorders of circulatory system
0.000 0.770 0.230
I10-I15 Hypertensive diseases
0.000 0.773 0.227
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.773 0.227
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.775 0.225
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.778 0.222
J12.9 Viral pneumonia, unspecified
0.000 0.780 0.220
J15.1 Pneumonia due to Pseudomonas
0.000 0.783 0.216
I06.0 Rheumatic aortic stenosis
0.000 0.784 0.215
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.785 0.215
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.786 0.214
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.791 0.209
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.791 0.209
J17.2 Pneumonia in mycoses
0.000 0.797 0.203
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.797 0.203
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.797 0.203
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.797 0.203
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.801 0.199
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.801 0.199
I98.0 Cardiovascular syphilis
0.000 0.801 0.199
I05.9 Mitral valve disease, unspecified
0.000 0.801 0.199
J21.9 Acute bronchiolitis, unspecified
0.000 0.801 0.198
J00 Acute nasopharyngitis [common cold]
0.000 0.804 0.196
J20.7 Acute bronchitis due to echovirus
0.000 0.807 0.193
J20.6 Acute bronchitis due to rhinovirus
0.000 0.807 0.193
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.807 0.193
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.807 0.193
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.807 0.193
J20.2 Acute bronchitis due to streptococcus
0.000 0.807 0.193
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.807 0.193
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.807 0.193
J45.8 Mixed asthma
0.000 0.807 0.192
J45.1 Nonallergic asthma
0.000 0.807 0.192
J20.8 Acute bronchitis due to other specified organisms
0.000 0.808 0.192
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.810 0.190
I95 Hypotension
0.000 0.813 0.187
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.815 0.185
J11.8 Influenza with other manifestations, virus not identified
0.001 0.817 0.182
J84.0 Alveolar and parietoalveolar conditions
0.000 0.822 0.177
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.824 0.176
J84.8 Other specified interstitial pulmonary diseases
0.000 0.824 0.175
J20.9 Acute bronchitis, unspecified
0.000 0.825 0.175
Z72.0 Tobacco use
0.000 0.827 0.173
Z72.1 Alcohol use
0.000 0.828 0.172
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.829 0.171
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.829 0.171
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.829 0.171
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.829 0.171
Z72 Problems related to lifestyle
0.000 0.831 0.169
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.831 0.168
I15 Secondary hypertension
0.000 0.832 0.168
F17.1 Harmful use
0.000 0.832 0.168
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.833 0.167
I95.1 Orthostatic hypotension
0.000 0.835 0.165
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.835 0.165
I13 Hypertensive heart and renal disease
0.000 0.837 0.163
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.839 0.161
I97.0 Postcardiotomy syndrome
0.000 0.839 0.161
J01 Acute sinusitis
0.000 0.839 0.160
I65.1 Occlusion and stenosis of basilar artery
0.001 0.841 0.158
J02 Acute pharyngitis
0.000 0.845 0.155
I87 Other disorders of veins
0.000 0.848 0.152
I95.8 Other hypotension
0.000 0.850 0.150
J04 Acute laryngitis and tracheitis
0.000 0.850 0.149
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.854 0.146
J03 Acute tonsillitis
0.000 0.855 0.145
J11.0 Influenza with pneumonia, virus not identified
0.001 0.855 0.144
I65.2 Occlusion and stenosis of carotid artery
0.000 0.856 0.144
J18.0 Bronchopneumonia, unspecified
0.000 0.857 0.143
I81 Portal vein thrombosis
0.000 0.857 0.143
I88 Nonspecific lymphadenitis
0.000 0.858 0.142
I85 Oesophageal varices
0.000 0.861 0.139
I87.1 Compression of vein
0.000 0.863 0.137
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.864 0.136
Z72.2 Drug use
0.000 0.864 0.136
I15.1 Hypertension secondary to other renal disorders
0.000 0.865 0.135
I80 Phlebitis and thrombophlebitis
0.000 0.865 0.135
J05.1 Acute epiglottitis
0.000 0.867 0.133
J05.0 Acute obstructive laryngitis [croup]
0.000 0.867 0.132
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.870 0.130
I15.9 Seconday hypertension, unspecified
0.000 0.871 0.129
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.873 0.127
J47 Bronchiectasis
0.000 0.874 0.126
I97.1 Other functional disturbances following cardiac surgery
0.000 0.874 0.126
I11 Hypertensive heart disease
0.000 0.876 0.124
F17.2 Dependence syndrome
0.000 0.876 0.124
I85.0 Oesophageal varices with bleeding
0.000 0.878 0.122
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.878 0.122
I87.8 Other specified disorders of veins
0.000 0.878 0.122
Z72.6 Gambling and betting
0.000 0.878 0.122
Z72.5 High-risk sexual behaviour
0.000 0.878 0.122
Z72.3 Lack of physical exercise
0.000 0.878 0.122
Z72.4 Inappropriate diet and eating habits
0.000 0.878 0.122
I12 Hypertensive renal disease
0.000 0.879 0.121
I15.8 Other secondary hypertension
0.000 0.879 0.121
I15.2 Hypertension secondary to endocrine disorders
0.000 0.879 0.121
Z72.8 Other problems related to lifestyle
0.000 0.880 0.120
J45.0 Predominantly allergic asthma
0.000 0.880 0.120
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.881 0.119
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.883 0.117
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.883 0.117
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.883 0.117
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.883 0.117
J01.0 Acute maxillary sinusitis
0.000 0.883 0.117
J01.8 Other acute sinusitis
0.000 0.885 0.115
J01.4 Acute pansinusitis
0.000 0.885 0.115
J01.3 Acute sphenoidal sinusitis
0.000 0.885 0.115
J01.1 Acute frontal sinusitis
0.000 0.885 0.115
J02.0 Streptococcal pharyngitis
0.000 0.885 0.115
J81 Pulmonary oedema
0.000 0.888 0.112
I95.0 Idiopathic hypotension
0.000 0.888 0.112
Z72.9 Problem related to lifestyle, unspecified
0.000 0.889 0.111
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.890 0.110
J01.2 Acute ethmoidal sinusitis
0.000 0.891 0.109
I87.9 Disorder of vein, unspecified
0.000 0.891 0.109
I87.0 Postphlebitic syndrome
0.000 0.891 0.109
J04.2 Acute laryngotracheitis
0.000 0.893 0.107
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.893 0.107
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.894 0.106
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.896 0.104
J03.0 Streptococcal tonsillitis
0.000 0.896 0.104
J04.1 Acute tracheitis
0.000 0.896 0.104
I88.8 Other nonspecific lymphadenitis
0.000 0.898 0.102
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.898 0.102
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.903 0.097
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.903 0.096
J01.9 Acute sinusitis, unspecified
0.000 0.903 0.097
I15.0 Renovascular hypertension
0.000 0.905 0.095
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.906 0.093
F17.8 Other mental and behavioural disorders
0.000 0.907 0.093
F17.7 Residual and late-onset psychotic disorder
0.000 0.907 0.093
F17.6 Amnesic syndrome
0.000 0.907 0.093
F17.5 Psychotic disorder
0.000 0.907 0.093
F17.4 Withdrawal state with delirium
0.000 0.907 0.093
F17.3 Withdrawal state
0.000 0.907 0.093
I63.8 Other cerebral infarction
0.000 0.908 0.092
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.908 0.092
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.909 0.091

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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