TreeWAS – Variant ID: rs4471613

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y45.0 Opioids and related analgesics	0.013	0.987	0.000
Y40.0 Penicillins	0.012	0.988	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.012	0.988	0.000
Y40 Systemic antibiotics	0.012	0.988	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.011	0.989	0.000
E21.0 Primary hyperparathyroidism	0.011	0.989	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.011	0.989	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.010	0.990	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.010	0.990	0.000
Y45.5 4-Aminophenol derivatives	0.009	0.991	0.000
Y52 Agents primarily affecting the cardiovascular system	0.009	0.991	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.009	0.991	0.000
Y40.8 Other systemic antibiotics	0.009	0.991	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
E22.0 Acromegaly and pituitary gigantism	0.009	0.991	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
Y40.3 Macrolides	0.009	0.991	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.009	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.009	0.991	0.000
Y45.4 Antirheumatics	0.009	0.991	0.000
E20-E35 Disorders of other endocrine glands	0.009	0.991	0.000
Y45.2 Propionic acid derivatives	0.009	0.991	0.000
Y40.7 Antifungal antibiotics, systemically used	0.008	0.991	0.000
Y40.6 Rifamycins	0.008	0.991	0.000
Y40.5 Aminoglycosides	0.008	0.991	0.000
Y40.4 Tetracyclines	0.008	0.991	0.000
Y40.2 Chloramphenicol group	0.008	0.991	0.000
Y57 Other and unspecified drugs and medicaments	0.008	0.992	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.008	0.992	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.008	0.992	0.000
Y59 Other and unspecified vaccines and biological substances	0.008	0.992	0.000
Y58 Bacterial vaccines	0.008	0.992	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.008	0.992	0.000
Y48 Anaesthetics and therapeutic gases	0.008	0.992	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.008	0.992	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.008	0.992	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.008	0.992	0.000
E21.4 Other specified disorders of parathyroid gland	0.008	0.992	0.000
E21.2 Other hyperparathyroidism	0.008	0.992	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.008	0.992	0.000
Y45.1 Salicylates	0.008	0.992	0.000
E22.1 Hyperprolactinaemia	0.008	0.992	0.000
Y44 Agents primarily affecting blood constituents	0.007	0.992	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.992	0.008
Y54.3 Benzothiadiazine derivatives	0.007	0.993	0.000
Y46.2 Hydantoin derivatives	0.007	0.993	0.000
E26 Hyperaldosteronism	0.007	0.993	0.000
Y49.5 Other antipsychotics and neuroleptics	0.007	0.993	0.000
Y46.4 Iminostilbenes	0.007	0.993	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
Y40.9 Systemic antibiotic, unspecified	0.007	0.993	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
Y57.8 Other drugs and medicaments	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
Y52.7 Peripheral vasodilators	0.007	0.993	0.000
Y52.1 Calcium-channel blockers	0.007	0.993	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
Y46.8 Antispasticity drugs	0.007	0.993	0.000
Y46.7 Anti-Parkinsonism drugs	0.007	0.993	0.000
Y46.6 Other and unspecified antiepileptics	0.007	0.993	0.000
Y46.5 Valproic acid	0.007	0.993	0.000
Y46.3 Deoxybarbiturates	0.007	0.993	0.000
Y46.1 Oxazolidinediones	0.007	0.993	0.000
Y46.0 Succinimides	0.007	0.993	0.000
Y54.5 Other diuretics	0.007	0.993	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.007	0.993	0.000
Y54.9 Mineral salts, not elsewhere classified	0.007	0.993	0.000
Y54.8 Agents affecting uric acid metabolism	0.007	0.993	0.000
Y54.7 Agents affecting calcification	0.007	0.993	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
Y54.4 Loop [high-ceiling] diuretics	0.007	0.993	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.007	0.993	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.007	0.993	0.000
Y54.0 Mineralocorticoids	0.007	0.993	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.007	0.993	0.000
E22.8 Other hyperfunction of pituitary gland	0.007	0.993	0.000
E29 Testicular dysfunction	0.007	0.993	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
Y49.9 Psychotropic drug, unspecified	0.006	0.993	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.006	0.993	0.000
Y49.7 Psychostimulants with abuse potential	0.006	0.993	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.006	0.993	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.993	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.993	0.000
Y49.2 Other and unspecified antidepressants	0.006	0.993	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.993	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.006	0.993	0.000
E34 Other endocrine disorders	0.006	0.993	0.000
E26.0 Primary hyperaldosteronism	0.006	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.993	0.000
E32 Diseases of thymus	0.006	0.993	0.000
E31 Polyglandular dysfunction	0.006	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.993	0.000
E25 Adrenogenital disorders	0.006	0.993	0.000
E20 Hypoparathyroidism	0.006	0.993	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.994	0.006
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
Y57.7 Vitamins, not elsewhere classified	0.006	0.994	0.000
Y57.6 Other diagnostic agents	0.006	0.994	0.000
Y57.4 Pharmaceutical excipients	0.006	0.994	0.000
Y57.3 Alcohol deterrents	0.006	0.994	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
Y57.1 Lipotropic drugs	0.006	0.994	0.000
Y57.0 Appetite depressants [anorectics]	0.006	0.994	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.006	0.994	0.000
Y56.9 Topical agent, unspecified	0.006	0.994	0.000
Y56.8 Other topical agents	0.006	0.994	0.000
Y56.7 Dental drugs, topically applied	0.006	0.994	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
Y56.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
Y56.3 Emollients, demulcents and protectants	0.006	0.994	0.000
Y56.2 Local astringents and local detergents	0.006	0.994	0.000
Y56.1 Antipruritics	0.006	0.994	0.000
E24 Cushing's syndrome	0.006	0.994	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.006	0.994	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.006	0.994	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.006	0.994	0.000
Y47.4 Bromine compounds	0.006	0.994	0.000
Y47.3 Paraldehyde	0.006	0.994	0.000
Y47.2 Chloral derivatives	0.006	0.994	0.000
Y47.1 Benzodiazepines	0.006	0.994	0.000
Y47.0 Barbiturates, not elsewhere classified	0.006	0.994	0.000
Y48.5 Therapeutic gases	0.006	0.994	0.000
Y48.4 Anaesthetic, unspecified	0.006	0.994	0.000
Y48.3 Local anaesthetics	0.006	0.994	0.000
Y48.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
Y48.1 Parenteral anaesthetics	0.006	0.994	0.000
Y48.0 Inhaled anaesthetics	0.006	0.994	0.000
Y50.9 Central nervous system stimulant, unspecified	0.006	0.994	0.000
Y50.8 Other central nervous system stimulants	0.006	0.994	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.006	0.994	0.000
Y50.1 Opioid receptor antagonists	0.006	0.994	0.000
Y50.0 Analeptics	0.006	0.994	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y53.7 Emetics	0.006	0.994	0.000
Y53.6 Antidiarrhoeal drugs	0.006	0.994	0.000
Y53.5 Digestants	0.006	0.994	0.000
Y53.4 Other laxatives	0.006	0.994	0.000
Y53.3 Saline and osmotic laxatives	0.006	0.994	0.000
Y53.2 Stimulant laxatives	0.006	0.994	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
Y53.0 Histamine H2-receptor antagonists	0.006	0.994	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
Y55.5 Anticommon cold drugs	0.006	0.994	0.000
Y55.4 Expectorants	0.006	0.994	0.000
Y55.3 Antitussives	0.006	0.994	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
Y55.0 Oxytocic drugs	0.006	0.994	0.000
Y58.9 Other and unspecified bacterial vaccines	0.006	0.994	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.006	0.994	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.006	0.994	0.000
Y58.5 Diphtheria vaccine	0.006	0.994	0.000
Y58.4 Tetanus vaccine	0.006	0.994	0.000
Y58.3 Plague vaccine	0.006	0.994	0.000
Y58.2 Cholera vaccine	0.006	0.994	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.006	0.994	0.000
Y58.0 BCG vaccine	0.006	0.994	0.000
Y59.9 Vaccine or biological substance, unspecified	0.006	0.994	0.000
Y59.8 Other specified vaccines and biological substances	0.006	0.994	0.000
Y59.3 Immunoglobulin	0.006	0.994	0.000
Y59.2 Protozoal vaccines	0.006	0.994	0.000
Y59.1 Rickettsial vaccines	0.006	0.994	0.000
Y59.0 Viral vaccines	0.006	0.994	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
Y41.5 Antiviral drugs	0.006	0.994	0.000
Y41.4 Anthelminthics	0.006	0.994	0.000
Y41.3 Other antiprotozoal drugs	0.006	0.994	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
Y41.1 Antimycobacterial drugs	0.006	0.994	0.000
Y41.0 Sulphonamides	0.006	0.994	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
Y51.0 Anticholinesterase agents	0.006	0.994	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.006	0.994	0.000
Y43.4 Immunosuppressive agents	0.006	0.994	0.000
E27.8 Other specified disorders of adrenal gland	0.006	0.994	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.005	0.994	0.000
Y44.7 Plasma substitutes	0.005	0.994	0.000
Y44.6 Natural blood and blood products	0.005	0.994	0.000
Y44.5 Thrombolytic drugs	0.005	0.994	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.005	0.994	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.994	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.005	0.994	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.005	0.994	0.000
E28 Ovarian dysfunction	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.994	0.000
E26.8 Other hyperaldosteronism	0.005	0.994	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.994	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.994	0.000
Y57.9 Drug or medicament, unspecified	0.005	0.994	0.000
Y42.9 Other and unspecified hormone antagonists	0.005	0.994	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.005	0.994	0.000
Y42.4 Oral contraceptives	0.005	0.994	0.000
Y42.2 Antithyroid drugs	0.005	0.994	0.000
Y42.1 Thyroid hormones and substitutes	0.005	0.994	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.994	0.000
J92.9 Pleural plaque without asbestos	0.005	0.995	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
E27.2 Addisonian crisis	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
E29.1 Testicular hypofunction	0.005	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.005	0.995	0.000
Y43.9 Primarily systemic agent, unspecified	0.005	0.995	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.995	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.995	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.995	0.000
Y43.2 Antineoplastic natural products	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
E27.1 Primary adrenocortical insufficiency	0.005	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
Y43.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
Y44.2 Anticoagulants	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.005	0.995	0.000
E34.5 Androgen resistance syndrome	0.005	0.995	0.000
E34.4 Constitutional tall stature	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.005	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.995	0.000
E34.0 Carcinoid syndrome	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.995	0.000
E25.8 Other adrenogenital disorders	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.995	0.000
E30.9 Disorder of puberty, unspecified	0.005	0.995	0.000
E30.8 Other disorders of puberty	0.005	0.995	0.000
E30.1 Precocious puberty	0.005	0.995	0.000
E30.0 Delayed puberty	0.005	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.995	0.000
E31.8 Other polyglandular dysfunction	0.005	0.995	0.000
E31.1 Polyglandular hyperfunction	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.995	0.000
E32.9 Disease of thymus, unspecified	0.005	0.995	0.000
E32.8 Other diseases of thymus	0.005	0.995	0.000
E32.1 Abscess of thymus	0.005	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.995	0.000
M65.34 Trigger finger-Hand	0.005	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
E24.8 Other Cushing's syndrome	0.004	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.995	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.004	0.995	0.000
E24.1 Nelson's syndrome	0.004	0.995	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.995	0.000
Y42.7 Androgens and anabolic congeners	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.995	0.000
E23.6 Other disorders of pituitary gland	0.004	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.995	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.004	0.996	0.000
E28.8 Other ovarian dysfunction	0.004	0.996	0.000
E28.3 Primary ovarian failure	0.004	0.996	0.000
E28.1 Androgen excess	0.004	0.996	0.000
E28.0 Oestrogen excess	0.004	0.996	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.996	0.004
E23.0 Hypopituitarism	0.004	0.996	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.996	0.004
J92.0 Pleural plaque with presence of asbestos	0.004	0.996	0.000
J92 Pleural plaque	0.004	0.996	0.000
Z45 Adjustment and management of implanted device	0.000	0.996	0.004
Z45.2 Adjustment and management of vascular access device	0.000	0.996	0.004
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
N60.8 Other benign mammary dysplasias	0.004	0.996	0.000
R20.2 Paraesthesia of skin	0.000	0.996	0.004
K80 Cholelithiasis	0.000	0.996	0.004
M65.3 Trigger finger	0.003	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
N60.0 Solitary cyst of breast	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.997	0.003
Z45.3 Adjustment and management of implanted hearing device	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.000	0.997	0.003
K80.4 Calculus of bile duct with cholecystitis	0.000	0.997	0.003
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.997	0.003
N60 Benign mammary dysplasia	0.003	0.997	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
N60.2 Fibroadenosis of breast	0.003	0.997	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.003	0.997	0.000
Y86 Sequelae of other accidents	0.003	0.997	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.997	0.003
B37.8 Candidiasis of other sites	0.003	0.997	0.000
K80.8 Other cholelithiasis	0.000	0.997	0.003
K80.3 Calculus of bile duct with cholangitis	0.000	0.997	0.003
M65.39 Trigger finger-Site unspec	0.003	0.997	0.000
M65.38 Trigger finger-Other	0.003	0.997	0.000
M65.37 Trigger finger-Ankle/foot	0.003	0.997	0.000
M65.36 Trigger finger-Lower leg	0.003	0.997	0.000
M65.35 Trigger finger-Pelvic/thigh	0.003	0.997	0.000
M65.33 Trigger finger-Forearm	0.003	0.997	0.000
M65.32 Trigger finger-Upper arm	0.003	0.997	0.000
M65.31 Trigger finger-Shldr region	0.003	0.997	0.000
M65.30 Trigger finger-Mult sites	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
Z45.1 Adjustment and management of infusion pump	0.000	0.997	0.003
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
N60.9 Benign mammary dysplasia, unspecified	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.997	0.000
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.997	0.003
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.997	0.000
M95.0 Acquired deformity of nose	0.002	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.002	0.998	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
M65 Synovitis and tenosynovitis	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.998	0.002
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
N32.0 Bladder-neck obstruction	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
T90 Sequelae of injuries of head	0.002	0.998	0.000
R49.0 Dysphonia	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
Y85 Sequelae of transport accidents	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
Y89 Sequelae of other external causes	0.002	0.998	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
M65.8 Other synovitis and tenosynovitis	0.002	0.998	0.000
M65.2 Calcific tendinitis	0.002	0.998	0.000
M65.1 Other infective (teno)synovitis	0.002	0.998	0.000
M65.0 Abscess of tendon sheath	0.002	0.998	0.000
S01.0 Open wound of scalp	0.000	0.998	0.002
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
T42.4 Benzodiazepines	0.000	0.998	0.002
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
T98.2 Sequelae of certain early complications of trauma	0.002	0.998	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
Chapter XX External causes of morbidity and mortality	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
R15 Faecal incontinence	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.002	0.998	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.002	0.998	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.002	0.998	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.002	0.998	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.002	0.998	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.998	0.002
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
Y87.2 Sequelae of events of undetermined intent	0.001	0.998	0.000
Y87.1 Sequelae of assault	0.001	0.998	0.000
Y87.0 Sequelae of intentional self-harm	0.001	0.998	0.000
Y89.9 Sequelae of unspecified external cause	0.001	0.998	0.000
Y89.1 Sequelae of war operations	0.001	0.998	0.000
Y89.0 Sequelae of legal intervention	0.001	0.998	0.000
X00-X09 Exposure to smoke, fire and flames	0.002	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.002	0.998	0.000
G54 Nerve root and plexus disorders	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.001	0.998	0.000
M65.08 Abscess of tendon sheath (Other)	0.001	0.998	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.001	0.998	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.001	0.998	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.001	0.998	0.000
M65.04 Abscess of tendon sheath (Hand)	0.001	0.998	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.001	0.998	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.001	0.998	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.001	0.998	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.001	0.998	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.001	0.998	0.000
M65.18 Other infective (teno)synovitis (Other)	0.001	0.998	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations