TreeWAS – Variant ID: rs4474465

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C16 Malignant neoplasm of stomach	0.000	0.843	0.157
C15 Malignant neoplasm of oesophagus	0.000	0.846	0.154
C15-C26 Malignant neoplasms of digestive organs	0.000	0.846	0.154
C16.0 Cardia	0.000	0.847	0.153
C15.5 Lower third of oesophagus	0.000	0.853	0.147
C16.2 Body of stomach	0.000	0.853	0.147
C15.9 Oesophagus, unspecified	0.000	0.854	0.146
C25 Malignant neoplasm of pancreas	0.000	0.862	0.138
C21 Malignant neoplasm of anus and anal canal	0.000	0.867	0.132
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.869	0.131
C16.3 Pyloric antrum	0.000	0.870	0.130
C20 Malignant neoplasm of rectum	0.000	0.870	0.130
C16.8 Overlapping lesion of stomach	0.000	0.873	0.126
C23 Malignant neoplasm of gallbladder	0.000	0.875	0.125
C25.9 Pancreas, unspecified	0.000	0.877	0.123
M20.1 Hallux valgus (acquired)	0.121	0.879	0.000
C15.0 Cervical part of oesophagus	0.000	0.880	0.120
C16.4 Pylorus	0.000	0.881	0.119
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.883	0.117
C21.0 Anus, unspecified	0.000	0.883	0.117
C15.1 Thoracic part of oesophagus	0.000	0.886	0.114
C25.8 Overlapping lesion of pancreas	0.000	0.888	0.111
C15.8 Overlapping lesion of oesophagus	0.000	0.889	0.111
C15.2 Abdominal part of oesophagus	0.000	0.889	0.111
C15.4 Middle third of oesophagus	0.000	0.889	0.111
C25.7 Other parts of pancreas	0.000	0.889	0.111
C16.1 Fundus of stomach	0.000	0.893	0.107
C25.0 Head of pancreas	0.000	0.893	0.107
C16.5 Lesser curvature of stomach, unspecified	0.000	0.895	0.105
C16.6 Greater curvature of stomach, unspecified	0.000	0.895	0.105
C25.3 Pancreatic duct	0.000	0.901	0.099
C21.1 Anal canal	0.000	0.902	0.098
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.902	0.097
C24.1 Ampulla of Vater	0.000	0.903	0.097
C21.2 Cloacogenic zone	0.000	0.905	0.095
C25.4 Endocrine pancreas	0.000	0.906	0.093
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.906	0.093
C25.2 Tail of pancreas	0.000	0.908	0.092
C15.3 Upper third of oesophagus	0.000	0.912	0.088
C24.8 Overlapping lesion of biliary tract	0.000	0.916	0.084
C25.1 Body of pancreas	0.000	0.918	0.082
C24.0 Extrahepatic bile duct	0.000	0.920	0.080
C24.9 Biliary tract, unspecified	0.000	0.920	0.079
C16.9 Stomach, unspecified	0.000	0.922	0.078
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.925	0.075
C26.8 Overlapping lesion of digestive system	0.000	0.930	0.070
C26.1 Spleen	0.000	0.930	0.070
C17 Malignant neoplasm of small intestine	0.000	0.930	0.070
M20 Acquired deformities of fingers and toes	0.070	0.930	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.932	0.068
M20.2 Hallux rigidus	0.064	0.936	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.060	0.940	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.940	0.059
C22.7 Other specified carcinomas of liver	0.000	0.946	0.054
C22.4 Other sarcomas of liver	0.000	0.946	0.054
C22.3 Angiosarcoma of liver	0.000	0.946	0.054
C22.2 Hepatoblastoma	0.000	0.946	0.054
C22.1 Intrahepatic bile duct carcinoma	0.000	0.946	0.053
C17.1 Jejunum	0.000	0.947	0.053
C17.8 Overlapping lesion of small intestine	0.000	0.949	0.050
C17.3 Meckel's diverticulum	0.000	0.949	0.050
C17.0 Duodenum	0.000	0.951	0.049
M20.5 Other deformities of toe(s) (acquired)	0.046	0.954	0.000
M20.3 Other deformity of hallux (acquired)	0.045	0.955	0.000
C22.0 Liver cell carcinoma	0.000	0.955	0.045
N18.3 Chronic kidney disease, stage 3	0.044	0.956	0.000
N18.9 Chronic renal failure, unspecified	0.043	0.957	0.000
N18 Chronic renal failure	0.042	0.958	0.000
M20.0 Deformity of finger(s)	0.040	0.959	0.000
M20.4 Other hammer toe(s) (acquired)	0.040	0.960	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.963	0.037
C17.2 Ileum	0.001	0.963	0.036
C22.9 Liver, unspecified	0.000	0.963	0.037
N18.1 Chronic kidney disease, stage 1	0.034	0.966	0.000
N18.4 Chronic kidney disease, stage 4	0.034	0.966	0.000
N18.2 Chronic kidney disease, stage 2	0.033	0.967	0.000
C17.9 Small intestine, unspecified	0.001	0.968	0.031
C18 Malignant neoplasm of colon	0.000	0.969	0.031
N18.0 End-stage renal disease	0.029	0.971	0.000
C18.4 Transverse colon	0.000	0.974	0.026
C18.6 Descending colon	0.000	0.974	0.026
N18.8 Other chronic renal failure	0.025	0.975	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.976	0.024
C18.5 Splenic flexure	0.000	0.976	0.024
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.977	0.023
C18.3 Hepatic flexure	0.000	0.977	0.023
C18.9 Colon, unspecified	0.000	0.977	0.022
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.980	0.020
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.980	0.020
C18.1 Appendix	0.000	0.981	0.019
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.982	0.018
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.982	0.018
C18.7 Sigmoid colon	0.000	0.983	0.017
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.984	0.016
N18.5 Chronic kidney disease, stage 5	0.016	0.984	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.984	0.016
I87.1 Compression of vein	0.000	0.985	0.015
M06 Other rheumatoid arthritis	0.000	0.985	0.015
T51.0 Ethanol	0.015	0.985	0.000
M06.3 Rheumatoid nodule	0.000	0.985	0.015
C18.8 Overlapping lesion of colon	0.001	0.986	0.014
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.986	0.014
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.986	0.014
M06.34 Rheumatoid nodule (Hand)	0.000	0.987	0.013
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.987	0.013
M06.4 Inflammatory polyarthropathy	0.000	0.988	0.012
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.988	0.012
M06.2 Rheumatoid bursitis	0.000	0.989	0.011
M06.1 Adult-onset Still's disease	0.000	0.989	0.011
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.989	0.011
M06.33 Rheumatoid nodule (Forearm)	0.000	0.989	0.011
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.989	0.011
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.989	0.011
M06.38 Rheumatoid nodule (Other)	0.000	0.989	0.011
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.989	0.011
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.989	0.011
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.990	0.010
C18.0 Caecum	0.000	0.990	0.010
M06.8 Other specified rheumatoid arthritis	0.000	0.990	0.010
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.990	0.009
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.991	0.009
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.991	0.009
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.991	0.009
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.991	0.009
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.991	0.009
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.991	0.009
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.991	0.009
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.991	0.009
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.991	0.009
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.992	0.008
M06.28 Rheumatoid bursitis (Other)	0.000	0.992	0.008
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.992	0.008
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.992	0.008
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.992	0.008
M06.24 Rheumatoid bursitis (Hand)	0.000	0.992	0.008
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.992	0.008
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.992	0.008
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.992	0.008
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.992	0.008
M06.18 Adult-onset Still's disease (Other)	0.000	0.992	0.008
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.992	0.008
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.992	0.008
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.992	0.008
M06.14 Adult-onset Still's disease (Hand)	0.000	0.992	0.008
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.992	0.008
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.992	0.008
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.992	0.008
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.992	0.008
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.992	0.008
T51 Toxic effect of alcohol	0.008	0.992	0.000
K66.0 Peritoneal adhesions	0.000	0.992	0.008
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.992	0.008
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.993	0.007
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.993	0.007
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.993	0.007
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.993	0.007
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.993	0.007
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.993	0.007
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.993	0.007
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.993	0.007
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.993	0.007
Z98.0 Intestinal bypass and anastomosis status	0.000	0.993	0.007
L50.9 Urticaria, unspecified	0.000	0.993	0.007
T51.9 Alcohol, unspecified	0.007	0.993	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.994	0.006
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.001	0.994	0.006
M06.0 Seronegative rheumatoid arthritis	0.001	0.994	0.006
T51.8 Other alcohols	0.006	0.994	0.000
T51.3 Fusel oil	0.006	0.994	0.000
T51.2 2-Propanol	0.006	0.994	0.000
T51.1 Methanol	0.006	0.994	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.994	0.006
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.006	0.994	0.000
H21 Other disorders of iris and ciliary body	0.000	0.994	0.006
S42.20 Fracture of upper end of humerus (closed)	0.000	0.994	0.006
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.995	0.005
M62.80 Other specified disorders of muscle (Multiple sites)	0.005	0.995	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.005	0.995	0.000
C18.2 Ascending colon	0.001	0.995	0.005
M62.8 Other specified disorders of muscle	0.005	0.995	0.000
I87 Other disorders of veins	0.000	0.995	0.005
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.995	0.005
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
H21.4 Pupillary membranes	0.000	0.995	0.005
D22.5 Melanocytic naevi of trunk	0.005	0.995	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.995	0.004
M10.90 Gout, unspecified (Multiple sites)	0.005	0.995	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.995	0.004
H21.0 Hyphaema	0.000	0.995	0.005
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.995	0.005
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.995	0.004
L50 Urticaria	0.000	0.995	0.005
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.995	0.004
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.001	0.995	0.004
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.995	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.005	0.995	0.000
M10.9 Gout, unspecified	0.005	0.995	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.995	0.004
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.005	0.995	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.995	0.004
H18 Other disorders of cornea	0.000	0.995	0.005
H21.2 Degeneration of iris and ciliary body	0.000	0.995	0.004
M62.88 Other specified disorders of muscle (Other)	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.995	0.005
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.995	0.004
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.000	0.995	0.005
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.996	0.004
L50.8 Other urticaria	0.000	0.996	0.004
M10.94 Gout, unspecified (Hand)	0.004	0.996	0.000
K65.9 Peritonitis, unspecified	0.000	0.996	0.004
M62.86 Other specified disorders of muscle (Lower leg)	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
H16.9 Keratitis, unspecified	0.000	0.996	0.004
C44.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.996	0.004
H16 Keratitis	0.000	0.996	0.004
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.996	0.004
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
I87.9 Disorder of vein, unspecified	0.000	0.996	0.004
M62.84 Other specified disorders of muscle (Hand)	0.004	0.996	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.004	0.996	0.000
K66 Other disorders of peritoneum	0.000	0.996	0.004
N17-N19 Renal failure	0.004	0.996	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.004	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.996	0.004
E07.9 Disorder of thyroid, unspecified	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
M10.92 Gout, unspecified (Upper arm)	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.004	0.996	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
F10.2 Dependence syndrome	0.000	0.996	0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
H18.7 Other corneal deformities	0.000	0.996	0.004
I87.0 Postphlebitic syndrome	0.000	0.996	0.004
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
I87.8 Other specified disorders of veins	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.000	0.996	0.004
H18.2 Other corneal oedema	0.000	0.996	0.004
L50.6 Contact urticaria	0.000	0.996	0.004
L50.5 Cholinergic urticaria	0.000	0.996	0.004
L50.4 Vibratory urticaria	0.000	0.996	0.004
L50.2 Urticaria due to cold and heat	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
H16.0 Corneal ulcer	0.000	0.996	0.004
L50.3 Dermatographic urticaria	0.000	0.996	0.004
R47.1 Dysarthria and anarthria	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
M10.93 Gout, unspecified (Forearm)	0.004	0.996	0.000
M10.98 Gout, unspecified (Other)	0.003	0.996	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M10.91 Gout, unspecified (Shoulder region)	0.003	0.996	0.000
L50.1 Idiopathic urticaria	0.000	0.996	0.003
T36.0 Penicillins	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.996	0.000
T50.5 Appetite depressants	0.003	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.996	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.996	0.004
H18.8 Other specified disorders of cornea	0.000	0.996	0.003
K25.3 Acute without haemorrhage or perforation	0.000	0.996	0.004
O16 Unspecified maternal hypertension	0.000	0.996	0.004
L50.0 Allergic urticaria	0.000	0.996	0.003
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.996	0.003
H17 Corneal scars and opacities	0.000	0.996	0.003
H18.6 Keratoconus	0.000	0.997	0.003
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.997	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
H15 Disorders of sclera	0.000	0.997	0.003
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.997	0.003
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.000	0.997	0.003
Z89.6 Acquired absence of leg above knee	0.003	0.997	0.000
S42.2 Fracture of upper end of humerus	0.000	0.997	0.003
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.997	0.003
T45.4 Iron and its compounds	0.003	0.997	0.000
Z98 Other postsurgical states	0.000	0.997	0.003
M10 Gout	0.002	0.997	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
F10.3 Withdrawal state	0.000	0.997	0.003
H20 Iridocyclitis	0.000	0.997	0.003
K65 Peritonitis	0.000	0.997	0.003
M25.57 Pain in joint (Ankle and foot)	0.000	0.997	0.003
M05-M14 Inflammatory polyarthropathies	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.003	0.997	0.000
H16.8 Other keratitis	0.000	0.997	0.003
M62.89 Other specified disorders of muscle (Site unspecified)	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
M35.3 Polymyalgia rheumatica	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
M62 Other disorders of muscle	0.003	0.997	0.000
H16.3 Interstitial and deep keratitis	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.997	0.003
M07.3 Other psoriatic arthropathies	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
H18.4 Corneal degeneration	0.000	0.997	0.003
M07 Psoriatic and enteropathic arthropathies	0.000	0.997	0.003
H16.4 Corneal neovascularisation	0.000	0.997	0.003
K65.8 Other peritonitis	0.000	0.997	0.003
E07 Other disorders of thyroid	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.000	0.997	0.003
H18.1 Bullous keratopathy	0.000	0.997	0.003
T36.4 Tetracyclines	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
G35 Multiple sclerosis	0.000	0.997	0.003
K66.9 Disorder of peritoneum, unspecified	0.000	0.997	0.003
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
H17.8 Other corneal scars and opacities	0.000	0.997	0.003
K51.5 Mucosal proctocolitis	0.000	0.997	0.003
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.000	0.997	0.003
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.997	0.003
H15.9 Disorder of sclera, unspecified	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.997	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
K65-K67 Diseases of peritoneum	0.000	0.997	0.003
H15.1 Episcleritis	0.000	0.997	0.003
M10.96 Gout, unspecified (Lower leg)	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.997	0.003
M08 Juvenile arthritis	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.997	0.003
H17.1 Other central corneal opacity	0.000	0.997	0.003
H17.0 Adherent leukoma	0.000	0.997	0.003
M12 Other specific arthropathies	0.000	0.997	0.002
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.000	0.997	0.003
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.003	0.997	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
K51 Ulcerative colitis	0.000	0.997	0.003
M07.38 Other psoriatic arthropathies (Other)	0.000	0.997	0.003
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.997	0.003
W55.0 Home	0.000	0.997	0.003
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.997	0.003
M10.4 Other secondary gout	0.002	0.997	0.001
M10.2 Drug-induced gout	0.002	0.997	0.001
M10.1 Lead-induced gout	0.002	0.997	0.001
M62.0 Diastasis of muscle	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
T41.5 Therapeutic gases	0.002	0.997	0.000
T41.4 Anaesthetic, unspecified	0.002	0.997	0.000
T41.3 Local anaesthetics	0.002	0.997	0.000
T41.1 Intravenous anaesthetics	0.002	0.997	0.000
T41.0 Inhaled anaesthetics	0.002	0.997	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.997	0.002
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.002
R82.8 Abnormal findings on cytological and histological examination of urine	0.003	0.997	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.997	0.002
M10.3 Gout due to impairment of renal function	0.002	0.997	0.001
D72.8 Other specified disorders of white blood cells	0.000	0.997	0.003
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.997	0.003
M08.9 Juvenile arthritis, unspecified	0.000	0.997	0.002
M62.9 Disorder of muscle, unspecified	0.002	0.997	0.000
T46.1 Calcium-channel blockers	0.002	0.997	0.000
Z98.1 Arthrodesis status	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.997	0.000
M10.0 Idiopathic gout	0.002	0.997	0.001
M62.3 Immobility syndrome (paraplegic)	0.002	0.997	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
T48.4 Expectorants	0.002	0.997	0.000
T48.3 Antitussives	0.002	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
T48.0 Oxytocic drugs	0.002	0.997	0.000
H15.8 Other disorders of sclera	0.000	0.997	0.002
H15.0 Scleritis	0.000	0.997	0.002
M12.2 Villonodular synovitis (pigmented)	0.000	0.997	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
T37.5 Antiviral drugs	0.002	0.997	0.000
T37.4 Anthelminthics	0.002	0.997	0.000
T37.3 Other antiprotozoal drugs	0.002	0.997	0.000
T37.1 Antimycobacterial drugs	0.002	0.997	0.000
T37.0 Sulphonamides	0.002	0.997	0.000
S42.21 Fracture of upper end of humerus (open)	0.000	0.997	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.997	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.997	0.002
H20.1 Chronic iridocyclitis	0.000	0.997	0.002
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.997	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.997	0.002
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.997	0.002
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.997	0.002
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.997	0.002
K66.8 Other specified disorders of peritoneum	0.000	0.997	0.002
M07.5 Arthropathy in ulcerative colitis	0.000	0.997	0.002
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.997	0.002
M07.2 Psoriatic spondylitis	0.000	0.997	0.002
M07.1 Arthritis mutilans	0.000	0.997	0.002
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.997	0.002
K66.1 Haemoperitoneum	0.000	0.998	0.002
M08.0 Juvenile rheumatoid arthritis	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.998	0.002
M62.4 Contracture of muscle	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.002	0.998	0.000
W55 Bitten or struck by other mammals	0.000	0.998	0.002
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.002
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.000	0.998	0.002
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.000	0.998	0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.002
M12.5 Traumatic arthropathy	0.000	0.998	0.002
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.000	0.998	0.002
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.000	0.998	0.002
L52 Erythema nodosum	0.000	0.998	0.002
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.002	0.998	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.998	0.002
M08.8 Other juvenile arthritis	0.000	0.998	0.002
M08.4 Pauciarticular juvenile arthritis	0.000	0.998	0.002
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.998	0.002
M08.1 Juvenile ankylosing spondylitis	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
W55.8 Other specified place	0.000	0.998	0.002
M14 Arthropathies in other diseases classified elsewhere	0.000	0.998	0.002
M07.6 Other enteropathic arthropathies	0.000	0.998	0.002
M08.2 Juvenile arthritis with systemic onset	0.000	0.998	0.002
M85.8 Other specified disorders of bone density and structure	0.000	0.998	0.002
M05 Seropositive rheumatoid arthritis	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
M62.6 Muscle strain	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
W55.7 Farm	0.000	0.998	0.002
L50-L54 Urticaria and erythema	0.000	0.998	0.002
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations