TreeWAS – Variant ID: rs4477910

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E80.4 Gilbert's syndrome	1.000	0.000	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.897	0.103	0.000
E80.6 Other disorders of bilirubin metabolism	0.867	0.133	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.703	0.297	0.000
E80.5 Crigler-Najjar syndrome	0.643	0.357	0.000
E80.3 Defects of catalase and peroxydase	0.643	0.357	0.000
E80.0 Hereditary erythropoietic porphyria	0.643	0.357	0.000
E80.1 Porphyria cutanea tarda	0.613	0.387	0.000
E80.2 Other porphyria	0.605	0.395	0.000
L42 Pityriasis rosea	0.308	0.692	0.000
E87.5 Hyperkalaemia	0.271	0.729	0.000
E70-E90 Metabolic disorders	0.268	0.732	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.264	0.736	0.000
E87.7 Fluid overload	0.245	0.755	0.000
E87.0 Hyperosmolality and hypernatraemia	0.241	0.759	0.000
E88 Other metabolic disorders	0.235	0.765	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.226	0.774	0.000
E70 Disorders of aromatic amino-acid metabolism	0.210	0.790	0.000
E84 Cystic fibrosis	0.210	0.790	0.000
E85 Amyloidosis	0.205	0.795	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.196	0.804	0.000
E77 Disorders of glycoprotein metabolism	0.192	0.808	0.000
E76 Disorders of glycosaminoglycan metabolism	0.192	0.808	0.000
E72 Other disorders of amino-acid metabolism	0.192	0.808	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.192	0.808	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.192	0.808	0.000
E74 Other disorders of carbohydrate metabolism	0.192	0.808	0.000
E87.4 Mixed disorder of acid-base balance	0.190	0.810	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.188	0.812	0.000
E79 Disorders of purine and pyrimidine metabolism	0.185	0.815	0.000
E70.3 Albinism	0.169	0.831	0.000
E88.9 Metabolic disorder, unspecified	0.169	0.831	0.000
E84.9 Cystic fibrosis, unspecified	0.168	0.832	0.000
E88.8 Other specified metabolic disorders	0.167	0.833	0.000
E85.9 Amyloidosis, unspecified	0.162	0.838	0.000
E88.3 Tumour lysis syndrome	0.162	0.838	0.000
E85.3 Secondary systemic amyloidosis	0.161	0.839	0.000
E87.6 Hypokalaemia	0.157	0.843	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.151	0.849	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.151	0.849	0.000
E70.2 Disorders of tyrosine metabolism	0.151	0.849	0.000
E70.1 Other hyperphenylalaninaemias	0.151	0.849	0.000
E70.0 Classical phenylketonuria	0.151	0.849	0.000
E84.8 Cystic fibrosis with other manifestations	0.150	0.849	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.150	0.849	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.150	0.849	0.000
E85.8 Other amyloidosis	0.147	0.852	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.147	0.852	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.147	0.852	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.147	0.852	0.000
E75.5 Other lipid storage disorders	0.146	0.854	0.000
E88.2 Lipomatosis, not elsewhere classified	0.143	0.857	0.000
E75.6 Lipid storage disorder, unspecified	0.141	0.859	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.141	0.859	0.000
E75.3 Sphingolipidosis, unspecified	0.141	0.859	0.000
E75.1 Other gangliosidosis	0.141	0.859	0.000
E75.0 GM2 gangliosidosis	0.141	0.859	0.000
E75.2 Other sphingolipidosis	0.139	0.861	0.000
E73 Lactose intolerance	0.138	0.861	0.000
E71.3 Disorders of fatty-acid metabolism	0.138	0.862	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.138	0.862	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.138	0.862	0.000
E71.0 Maple-syrup-urine disease	0.138	0.862	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.138	0.862	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.138	0.862	0.000
E72.5 Disorders of glycine metabolism	0.138	0.862	0.000
E72.4 Disorders of ornithine metabolism	0.138	0.862	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.138	0.862	0.000
E72.2 Disorders of urea cycle metabolism	0.138	0.862	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.138	0.862	0.000
E72.0 Disorders of amino-acid transport	0.138	0.862	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.138	0.862	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.138	0.862	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.138	0.862	0.000
E76.2 Other mucopolysaccharidoses	0.138	0.862	0.000
E76.1 Mucopolysaccharidosis, type II	0.138	0.862	0.000
E76.0 Mucopolysaccharidosis, type I	0.138	0.862	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.138	0.862	0.000
E77.8 Other disorders of glycoprotein metabolism	0.138	0.862	0.000
E77.1 Defects in glycoprotein degradation	0.138	0.862	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.138	0.862	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.138	0.862	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.138	0.862	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.138	0.862	0.000
E74.2 Disorders of galactose metabolism	0.138	0.862	0.000
E74.1 Disorders of fructose metabolism	0.138	0.862	0.000
E74.0 Glycogen storage disease	0.138	0.862	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.137	0.863	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.135	0.865	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.133	0.867	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.133	0.867	0.000
E79.1 Lesch-Nyhan syndrome	0.133	0.867	0.000
E85.4 Organ-limited amyloidosis	0.128	0.872	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.126	0.874	0.000
E73.8 Other lactose intolerance	0.099	0.900	0.000
E73.1 Secondary lactase deficiency	0.099	0.900	0.000
E73.0 Congenital lactase deficiency	0.099	0.900	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.092	0.908	0.000
E78.4 Other hyperlipidaemia	0.089	0.911	0.000
E87.3 Alkalosis	0.084	0.915	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.081	0.919	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.072	0.928	0.000
E78.1 Pure hyperglyceridaemia	0.072	0.928	0.000
E78.3 Hyperchylomicronaemia	0.065	0.935	0.000
I38 Endocarditis, valve unspecified	0.000	0.936	0.064
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.061	0.939	0.000
L40-L45 Papulosquamous disorders	0.051	0.949	0.000
E78.2 Mixed hyperlipidaemia	0.050	0.950	0.000
E78.8 Other disorders of lipoprotein metabolism	0.049	0.951	0.000
E78.6 Lipoprotein deficiency	0.048	0.952	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.047	0.953	0.000
E73.9 Lactose intolerance, unspecified	0.046	0.953	0.001
E89.2 Postprocedural hypoparathyroidism	0.045	0.955	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.044	0.956	0.000
E89.5 Postprocedural testicular hypofunction	0.044	0.956	0.000
E89.1 Postprocedural hypoinsulinaemia	0.044	0.956	0.000
E87.2 Acidosis	0.041	0.959	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.040	0.959	0.000
L44 Other papulosquamous disorders	0.036	0.963	0.000
L41 Parapsoriasis	0.036	0.963	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.036	0.963	0.000
E89.4 Postprocedural ovarian failure	0.033	0.966	0.000
L43 Lichen planus	0.032	0.968	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.032	0.968	0.000
E89.3 Postprocedural hypopituitarism	0.030	0.969	0.000
E83 Disorders of mineral metabolism	0.028	0.972	0.000
L41.9 Parapsoriasis, unspecified	0.026	0.973	0.000
L41.8 Other parapsoriasis	0.026	0.973	0.000
L41.5 Retiform parapsoriasis	0.026	0.973	0.000
L41.4 Large plaque parapsoriasis	0.026	0.973	0.000
L41.3 Small plaque parapsoriasis	0.026	0.973	0.000
L41.2 Lymphomatoid papulosis	0.026	0.973	0.000
L41.1 Pityriasis lichenoides chronica	0.026	0.973	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.026	0.973	0.000
L44.9 Papulosquamous disorder, unspecified	0.026	0.973	0.000
L44.8 Other specified papulosquamous disorders	0.026	0.973	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.026	0.973	0.000
L44.3 Lichen ruber moniliformis	0.026	0.973	0.000
L44.2 Lichen striatus	0.026	0.973	0.000
L44.1 Lichen nitidus	0.026	0.973	0.000
L44.0 Pityriasis rubra pilaris	0.026	0.973	0.000
H54.9 Unspecified visual impairment (binocular)	0.026	0.974	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.976	0.024
E86 Volume depletion	0.024	0.976	0.000
L43.8 Other lichen planus	0.024	0.976	0.000
L43.3 Subacute (active) lichen planus	0.023	0.976	0.000
L43.2 Lichenoid drug reaction	0.023	0.976	0.000
L43.1 Bullous lichen planus	0.023	0.976	0.000
L43.0 Hypertrophic lichen planus	0.023	0.976	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.020	0.979	0.000
E83.8 Other disorders of mineral metabolism	0.020	0.979	0.000
E83.2 Disorders of zinc metabolism	0.020	0.979	0.000
E83.0 Disorders of copper metabolism	0.020	0.979	0.000
L43.9 Lichen planus, unspecified	0.019	0.981	0.000
R94.5 Abnormal results of liver function studies	0.018	0.982	0.000
E83.3 Disorders of phosphorus metabolism	0.018	0.982	0.000
E83.4 Disorders of magnesium metabolism	0.017	0.983	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.015	0.985	0.000
H54 Blindness and low vision	0.014	0.986	0.000
K80 Cholelithiasis	0.014	0.986	0.000
H54.2 Low vision, both eyes	0.013	0.987	0.000
M17.0 Primary gonarthrosis, bilateral	0.012	0.988	0.000
H54.0 Blindness, both eyes	0.012	0.988	0.000
R61 Hyperhidrosis	0.000	0.989	0.011
E78.5 Hyperlipidaemia, unspecified	0.011	0.989	0.000
H54.1 Blindness, one eye, low vision, other eye	0.011	0.989	0.000
H54.3 Unqualified visual loss, both eyes	0.010	0.989	0.000
K80.3 Calculus of bile duct with cholangitis	0.010	0.989	0.000
K80.4 Calculus of bile duct with cholecystitis	0.010	0.990	0.000
H54.6 Unqualified visual loss, one eye	0.010	0.990	0.000
L40 Psoriasis	0.010	0.990	0.000
F52.2 Failure of genital response	0.010	0.990	0.000
H54.4 Blindness, one eye	0.010	0.990	0.000
E16.2 Hypoglycaemia, unspecified	0.009	0.991	0.000
H54.5 Low vision, one eye	0.009	0.991	0.000
R61.0 Localised hyperhidrosis	0.000	0.991	0.009
E16 Other disorders of pancreatic internal secretion	0.009	0.991	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.009	0.991	0.000
R61.1 Generalised hyperhidrosis	0.000	0.992	0.008
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.008	0.992	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.008	0.992	0.000
H54.7 Unspecified visual loss	0.008	0.992	0.000
L40.8 Other psoriasis	0.008	0.992	0.000
F52.0 Lack or loss of sexual desire	0.008	0.992	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.008	0.992	0.000
L40.1 Generalised pustular psoriasis	0.008	0.992	0.000
E16.1 Other hypoglycaemia	0.007	0.993	0.000
L40.3 Pustulosis palmaris et plantaris	0.007	0.993	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.007	0.993	0.000
L40.2 Acrodermatitis continua	0.007	0.993	0.000
E89.0 Postprocedural hypothyroidism	0.007	0.993	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.007	0.993	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.006	0.993	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.006	0.993	0.000
E16.4 Abnormal secretion of gastrin	0.006	0.993	0.000
E16.3 Increased secretion of glucagon	0.006	0.993	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.006	0.993	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.006	0.993	0.000
F52.7 Excessive sexual drive	0.006	0.993	0.000
F52.6 Nonorganic dyspareunia	0.006	0.993	0.000
F52.5 Nonorganic vaginismus	0.006	0.993	0.000
F52.4 Premature ejaculation	0.006	0.993	0.000
F52.3 Orgasmic dysfunction	0.006	0.993	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.006	0.993	0.000
L40.4 Guttate psoriasis	0.006	0.993	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.006	0.993	0.000
A49.8 Other bacterial infections of unspecified site	0.006	0.994	0.000
F50 Eating disorders	0.006	0.994	0.000
F50.9 Eating disorder, unspecified	0.006	0.994	0.000
E15 Nondiabetic hypoglycaemic coma	0.006	0.994	0.000
F51 Nonorganic sleep disorders	0.006	0.994	0.000
E40-E46 Malnutrition	0.006	0.994	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.006	0.994	0.000
L40.0 Psoriasis vulgaris	0.005	0.995	0.000
R17 Unspecified jaundice	0.005	0.995	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.005	0.995	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.005	0.995	0.000
F55 Abuse of non-dependence-producing substances	0.005	0.995	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.005	0.995	0.000
A49.0 Staphylococcal infection, unspecified	0.005	0.995	0.000
F50.0 Anorexia nervosa	0.005	0.995	0.000
F51.5 Nightmares	0.005	0.995	0.000
S22.20 Fracture of sternum (closed)	0.000	0.995	0.005
F50.8 Other eating disorders	0.005	0.995	0.000
F50.5 Vomiting associated with other psychological disturbances	0.005	0.995	0.000
F50.4 Overeating associated with other psychological disturbances	0.005	0.995	0.000
F50.3 Atypical bulimia nervosa	0.005	0.995	0.000
F50.1 Atypical anorexia nervosa	0.005	0.995	0.000
F51.4 Sleep terrors [night terrors]	0.005	0.995	0.000
K50.0 Crohn's disease of small intestine	0.000	0.995	0.005
A49 Bacterial infection of unspecified site	0.005	0.995	0.000
F32.0 Mild depressive episode	0.005	0.995	0.000
M17 Gonarthrosis [arthrosis of knee]	0.005	0.995	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.005	0.995	0.000
E50-E64 Other nutritional deficiencies	0.005	0.995	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.004	0.995	0.000
F51.8 Other nonorganic sleep disorders	0.004	0.995	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.004	0.995	0.000
F51.1 Nonorganic hypersomnia	0.004	0.995	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.004	0.995	0.000
E45 Retarded development following protein-energy malnutrition	0.004	0.995	0.000
E43 Unspecified severe protein-energy malnutrition	0.004	0.995	0.000
E42 Marasmic kwashiorkor	0.004	0.995	0.000
E41 Nutritional marasmus	0.004	0.995	0.000
E40 Kwashiorkor	0.004	0.995	0.000
F51.3 Sleepwalking [somnambulism]	0.004	0.995	0.000
K80.8 Other cholelithiasis	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
C50.1 Central portion of breast	0.004	0.996	0.000
M17.1 Other primary gonarthrosis	0.004	0.996	0.000
F34.1 Dysthymia	0.004	0.996	0.000
A49.1 Streptococcal infection, unspecified	0.004	0.996	0.000
F50.2 Bulimia nervosa	0.004	0.996	0.000
E46 Unspecified protein-energy malnutrition	0.004	0.996	0.000
O00.1 Tubal pregnancy	0.004	0.996	0.000
F51.0 Nonorganic insomnia	0.004	0.996	0.000
F34 Persistent mood [affective] disorders	0.004	0.996	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.004	0.996	0.000
F33.9 Recurrent depressive disorder, unspecified	0.004	0.996	0.000
F53.9 Puerperal mental disorder, unspecified	0.004	0.996	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.004	0.996	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.004	0.996	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.004	0.996	0.000
F30-F39 Mood [affective] disorders	0.004	0.996	0.000
E28.3 Primary ovarian failure	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.996	0.000
E21.2 Other hyperparathyroidism	0.004	0.996	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.996	0.000
M17.3 Other posttraumatic gonarthrosis	0.004	0.996	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.004	0.996	0.000
R94 Abnormal results of function studies	0.004	0.996	0.000
A49.3 Mycoplasma infection, unspecified	0.004	0.996	0.000
F33 Recurrent depressive disorder	0.004	0.996	0.000
F31 Bipolar affective disorder	0.004	0.996	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.004	0.996	0.000
E51 Thiamine deficiency	0.004	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.996	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.004	0.996	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.003	0.996	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.003	0.996	0.000
Y79.0 Diagnostic and monitoring devices	0.003	0.996	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.003	0.996	0.000
E63 Other nutritional deficiencies	0.003	0.996	0.000
E56 Other vitamin deficiencies	0.003	0.996	0.000
E50 Vitamin A deficiency	0.003	0.996	0.000
E60 Dietary zinc deficiency	0.003	0.996	0.000
E59 Dietary selenium deficiency	0.003	0.996	0.000
E52 Niacin deficiency [pellagra]	0.003	0.996	0.000
E44.1 Mild protein-energy malnutrition	0.003	0.996	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.996	0.000
E54 Ascorbic acid deficiency	0.003	0.996	0.000
M17.5 Other secondary gonarthrosis	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.003	0.997	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.997	0.003
E58 Dietary calcium deficiency	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.003	0.997	0.000
F34.0 Cyclothymia	0.003	0.997	0.000
F80.1 Expressive language disorder	0.003	0.997	0.000
F30 Manic episode	0.003	0.997	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.997	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.003	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.997	0.000
S22.2 Fracture of sternum	0.000	0.997	0.003
E55 Vitamin D deficiency	0.003	0.997	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.003	0.997	0.000
F38 Other mood [affective] disorders	0.003	0.997	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.003	0.997	0.000
R94.7 Abnormal results of other endocrine function studies	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
F39 Unspecified mood [affective] disorder	0.003	0.997	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.003	0.997	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E51.2 Wernicke's encephalopathy	0.003	0.997	0.000
R94.6 Abnormal results of thyroid function studies	0.003	0.997	0.000
F32 Depressive episode	0.003	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.003	0.997	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
F30.2 Mania with psychotic symptoms	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.003	0.997	0.000
E51.8 Other manifestations of thiamine deficiency	0.003	0.997	0.000
E51.1 Beriberi	0.003	0.997	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.003	0.997	0.000
F80 Specific developmental disorders of speech and language	0.003	0.997	0.000
H52.2 Astigmatism	0.000	0.997	0.003
Q82.8 Other specified congenital malformations of skin	0.000	0.997	0.003
E50.9 Vitamin A deficiency, unspecified	0.003	0.997	0.000
E50.8 Other manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.003	0.997	0.000
E50.5 Vitamin A deficiency with night blindness	0.003	0.997	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.003	0.997	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.003	0.997	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.003	0.997	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.003	0.997	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.003	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.003	0.997	0.000
E56.9 Vitamin deficiency, unspecified	0.003	0.997	0.000
E56.8 Deficiency of other vitamins	0.003	0.997	0.000
E56.1 Deficiency of vitamin K	0.003	0.997	0.000
E56.0 Deficiency of vitamin E	0.003	0.997	0.000
E63.9 Nutritional deficiency, unspecified	0.003	0.997	0.000
E63.8 Other specified nutritional deficiencies	0.003	0.997	0.000
E63.1 Imbalance of constituents of food intake	0.003	0.997	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.003	0.997	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.003	0.997	0.000
E64.8 Sequelae of other nutritional deficiencies	0.003	0.997	0.000
E64.3 Sequelae of rickets	0.003	0.997	0.000
E64.2 Sequelae of vitamin C deficiency	0.003	0.997	0.000
E64.1 Sequelae of vitamin A deficiency	0.003	0.997	0.000
E64.0 Sequelae of protein-energy malnutrition	0.003	0.997	0.000
F30.1 Mania without psychotic symptoms	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.000	0.997	0.003
E25 Adrenogenital disorders	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.003	0.997	0.000
R94.4 Abnormal results of kidney function studies	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
Z92.0 Personal history of contraception	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
E24 Cushing's syndrome	0.003	0.997	0.000
F30.8 Other manic episodes	0.002	0.997	0.000
F32.8 Other depressive episodes	0.003	0.997	0.000
D18.0 Haemangioma, any site	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.002	0.997	0.000
E20 Hypoparathyroidism	0.002	0.997	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.997	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.000	0.997	0.002
E55.0 Rickets, active	0.002	0.997	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.997	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.997	0.000
F38.0 Other single mood [affective] disorders	0.002	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.003	0.997	0.000
F80-F89 Disorders of psychological development	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.997	0.000
E26.8 Other hyperaldosteronism	0.002	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.997	0.000
E30.8 Other disorders of puberty	0.002	0.997	0.000
E30.1 Precocious puberty	0.002	0.997	0.000
E30.0 Delayed puberty	0.002	0.997	0.000
E32.9 Disease of thymus, unspecified	0.002	0.997	0.000
E32.8 Other diseases of thymus	0.002	0.997	0.000
E32.1 Abscess of thymus	0.002	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.997	0.000
E53.1 Pyridoxine deficiency	0.002	0.997	0.000
E53.0 Riboflavin deficiency	0.002	0.997	0.000
R94.0 Abnormal results of function studies of central nervous system	0.002	0.997	0.000
H53-H54 Visual disturbances and blindness	0.002	0.997	0.000
D75.1 Secondary polycythaemia	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.002	0.998	0.000
Chapter V Mental and behavioural disorders	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
F30.0 Hypomania	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
F80.2 Receptive language disorder	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
Y81.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
R94.2 Abnormal results of pulmonary function studies	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.002	0.998	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.998	0.000
F80.0 Specific speech articulation disorder	0.002	0.998	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.998	0.002
E83.5 Disorders of calcium metabolism	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.002	0.998	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
G45.4 Transient global amnesia	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.998	0.002
Y71.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
Y80 Physical medicine devices associated with adverse incidents	0.002	0.998	0.000
Y78 Radiological devices associated with adverse incidents	0.002	0.998	0.000
Y75 Neurological devices associated with adverse incidents	0.002	0.998	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.002	0.998	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.002	0.998	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
Z22.5 Carrier of viral hepatitis	0.002	0.998	0.000
F89 Unspecified disorder of psychological development	0.002	0.998	0.000
F88 Other disorders of psychological development	0.002	0.998	0.000
F83 Mixed specific developmental disorders	0.002	0.998	0.000
F82 Specific developmental disorder of motor function	0.002	0.998	0.000
Y71.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
F70-F79 Mental retardation	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.000	0.998	0.002
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
F84 Pervasive developmental disorders	0.002	0.998	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.002	0.998	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998	0.000
Y81.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y81.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations