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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs447921
log Bayes Factor = <0.0001
Chromosome 17   position 74,414,559  (GRCh37) Explore rs447921 on Ensembl!
Variant rs447921 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z93.2 Ileostomy status
0.000 0.960 0.040
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.965 0.035
I69 Sequelae of cerebrovascular disease
0.000 0.966 0.034
Z93 Artificial opening status
0.000 0.967 0.033
I69.3 Sequelae of cerebral infarction
0.000 0.967 0.033
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.968 0.032
Z93.6 Other artificial openings of urinary tract status
0.000 0.968 0.032
Z93.3 Colostomy status
0.000 0.970 0.030
Z93.8 Other artificial opening status
0.000 0.972 0.028
Z93.5 Cystostomy status
0.000 0.973 0.027
Z93.4 Other artificial openings of gastro-intestinal tract status
0.000 0.974 0.026
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.975 0.025
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.976 0.024
Z93.9 Artificial opening status, unspecified
0.000 0.976 0.023
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.977 0.023
Z93.0 Tracheostomy status
0.000 0.978 0.022
I60-I69 Cerebrovascular diseases
0.000 0.986 0.014
I62 Other nontraumatic intracranial haemorrhage
0.000 0.986 0.014
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.986 0.013
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.987 0.013
I63 Cerebral infarction
0.000 0.987 0.013
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.988 0.012
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.989 0.011
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.989 0.011
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.989 0.011
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.989 0.011
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.990 0.010
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.990 0.010
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.990 0.010
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.990 0.009
I62.1 Nontraumatic extradural haemorrhage
0.000 0.991 0.009
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.991 0.009
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.991 0.009
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.991 0.009
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.991 0.009
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.991 0.009
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.991 0.009
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.991 0.009
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.991 0.009
N05 Unspecified nephritic syndrome
0.000 0.991 0.009
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.009 0.991 0.000
I68.0 Cerebral amyloid angiopathy
0.000 0.991 0.008
N05.9 Unspecified
0.000 0.992 0.008
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.992 0.008
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.992 0.008
N05.1 Focal and segmental glomerular lesions
0.000 0.992 0.008
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.992 0.008
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.992 0.008
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.992 0.008
Z45.2 Adjustment and management of vascular access device
0.000 0.992 0.008
I60 Subarachnoid haemorrhage
0.000 0.992 0.008
N03.9 Unspecified
0.000 0.992 0.008
I65.2 Occlusion and stenosis of carotid artery
0.000 0.992 0.008
G81.9 Hemiplegia, unspecified
0.000 0.992 0.008
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.008 0.992 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.992 0.008
I61 Intracerebral haemorrhage
0.000 0.992 0.008
N03 Chronic nephritic syndrome
0.000 0.992 0.008
N00-N08 Glomerular diseases
0.000 0.992 0.008
Y52.3 Coronary vasodilators, not elsewhere classified
0.007 0.992 0.000
Y45.0 Opioids and related analgesics
0.007 0.993 0.000
Z93.1 Gastrostomy status
0.000 0.993 0.007
I63.8 Other cerebral infarction
0.000 0.993 0.007
Y52 Agents primarily affecting the cardiovascular system
0.007 0.993 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.993 0.007
I63.9 Cerebral infarction, unspecified
0.000 0.993 0.007
G83.4 Cauda equina syndrome
0.000 0.993 0.007
I60.8 Other subarachnoid haemorrhage
0.000 0.993 0.007
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.993 0.007
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.993 0.007
N05.2 Diffuse membranous glomerulonephritis
0.000 0.993 0.007
Y45.1 Salicylates
0.007 0.993 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.993 0.007
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.007 0.993 0.000
N04 Nephrotic syndrome
0.000 0.993 0.007
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.993 0.007
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.993 0.007
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.993 0.006
N05.6 Dense deposit disease
0.000 0.993 0.006
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.993 0.006
N05.0 Minor glomerular abnormality
0.000 0.993 0.006
N02 Recurrent and persistent haematuria
0.000 0.993 0.007
N05.8 Other
0.000 0.994 0.006
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.006 0.994 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.994 0.006
D86 Sarcoidosis
0.000 0.994 0.006
Y45.4 Antirheumatics
0.006 0.994 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.994 0.006
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.994 0.006
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.994 0.006
N03.1 Focal and segmental glomerular lesions
0.000 0.994 0.006
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.994 0.006
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.006 0.994 0.000
D86.0 Sarcoidosis of lung
0.000 0.994 0.006
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.000 0.994 0.006
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.994 0.006
I65.1 Occlusion and stenosis of basilar artery
0.000 0.994 0.006
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.994 0.006
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.006 0.994 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.994 0.006
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.994 0.006
Y45.8 Other analgesics and antipyretics
0.006 0.994 0.000
N04.9 Unspecified
0.000 0.994 0.006
N03.7 Diffuse crescentic glomerulonephritis
0.000 0.994 0.006
N03.6 Dense deposit disease
0.000 0.994 0.006
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.994 0.006
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.994 0.006
N03.2 Diffuse membranous glomerulonephritis
0.000 0.994 0.006
N03.0 Minor glomerular abnormality
0.000 0.994 0.006
G81 Hemiplegia
0.000 0.994 0.006
C02.9 Tongue, unspecified
0.000 0.994 0.006
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.994 0.006
N06 Isolated proteinuria with specified morphological lesion
0.000 0.994 0.006
N01 Rapidly progressive nephritic syndrome
0.000 0.994 0.006
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.994 0.005
Y52.7 Peripheral vasodilators
0.006 0.994 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.005 0.994 0.000
N04.1 Focal and segmental glomerular lesions
0.000 0.994 0.005
Y45.2 Propionic acid derivatives
0.005 0.994 0.000
Y45.5 4-Aminophenol derivatives
0.005 0.994 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.006 0.994 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.994 0.005
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.994 0.005
N02.2 Diffuse membranous glomerulonephritis
0.000 0.994 0.005
N03.8 Other
0.000 0.994 0.005
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.994 0.005
Y52.8 Antivaricose drugs, including sclerosing agents
0.005 0.995 0.000
N02.8 Other
0.000 0.995 0.005
N00 Acute nephritic syndrome
0.000 0.995 0.005
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.995 0.005
Y44 Agents primarily affecting blood constituents
0.005 0.995 0.000
N04.8 Other
0.000 0.995 0.005
Y44.2 Anticoagulants
0.005 0.995 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.005 0.995 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.005 0.995 0.000
G83 Other paralytic syndromes
0.000 0.995 0.005
N04.2 Diffuse membranous glomerulonephritis
0.000 0.995 0.005
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.995 0.005
I61.8 Other intracerebral haemorrhage
0.000 0.995 0.005
N02.1 Focal and segmental glomerular lesions
0.000 0.995 0.005
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.995 0.005
N04.6 Dense deposit disease
0.000 0.995 0.005
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.995 0.005
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.995 0.005
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.995 0.005
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.995 0.005
Y54.4 Loop [high-ceiling] diuretics
0.005 0.995 0.000
M35.3 Polymyalgia rheumatica
0.000 0.995 0.005
N18.9 Chronic renal failure, unspecified
0.000 0.995 0.005
N02.9 Unspecified
0.000 0.995 0.005
N04.0 Minor glomerular abnormality
0.000 0.995 0.005
N02.7 Diffuse crescentic glomerulonephritis
0.000 0.995 0.005
N02.6 Dense deposit disease
0.000 0.995 0.005
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.995 0.005
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.995 0.005
Z09.0 Follow-up examination after surgery for other conditions
0.000 0.995 0.005
Z45.1 Adjustment and management of infusion pump
0.000 0.995 0.005
N02.0 Minor glomerular abnormality
0.000 0.995 0.005
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.995 0.005
Y57 Other and unspecified drugs and medicaments
0.005 0.995 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.005 0.995 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.995 0.005
Y52.1 Calcium-channel blockers
0.005 0.995 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.005 0.995 0.000
Y57.9 Drug or medicament, unspecified
0.005 0.995 0.000
Y58 Bacterial vaccines
0.005 0.995 0.000
D86.3 Sarcoidosis of skin
0.000 0.995 0.004
G83.1 Monoplegia of lower limb
0.000 0.995 0.004
Y50 Central nervous system stimulants, not elsewhere classified
0.004 0.995 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.005 0.995 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.005 0.995 0.000
G81.1 Spastic hemiplegia
0.000 0.995 0.004
Y54.0 Mineralocorticoids
0.004 0.995 0.000
Y86 Sequelae of other accidents
0.005 0.995 0.000
Y54.8 Agents affecting uric acid metabolism
0.004 0.995 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.996 0.004
G81.0 Flaccid hemiplegia
0.000 0.996 0.004
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.996 0.004
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.004 0.996 0.000
N01.9 Unspecified
0.000 0.996 0.004
N01.8 Other
0.000 0.996 0.004
N01.7 Diffuse crescentic glomerulonephritis
0.000 0.996 0.004
N01.6 Dense deposit disease
0.000 0.996 0.004
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.996 0.004
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.996 0.004
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.996 0.004
N01.2 Diffuse membranous glomerulonephritis
0.000 0.996 0.004
N01.1 Focal and segmental glomerular lesions
0.000 0.996 0.004
N01.0 Minor glomerular abnormality
0.000 0.996 0.004
N06.9 Unspecified
0.000 0.996 0.004
N06.8 Other
0.000 0.996 0.004
N06.7 Diffuse crescentic glomerulonephritis
0.000 0.996 0.004
N06.6 Dense deposit disease
0.000 0.996 0.004
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.996 0.004
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.996 0.004
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.996 0.004
N06.2 Diffuse membranous glomerulonephritis
0.000 0.996 0.004
N06.1 Focal and segmental glomerular lesions
0.000 0.996 0.004
N06.0 Minor glomerular abnormality
0.000 0.996 0.004
N07.9 Unspecified
0.000 0.996 0.004
N07.8 Other
0.000 0.996 0.004
N07.7 Diffuse crescentic glomerulonephritis
0.000 0.996 0.004
N07.6 Dense deposit disease
0.000 0.996 0.004
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.996 0.004
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.996 0.004
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.996 0.004
N07.2 Diffuse membranous glomerulonephritis
0.000 0.996 0.004
N07.1 Focal and segmental glomerular lesions
0.000 0.996 0.004
N07.0 Minor glomerular abnormality
0.000 0.996 0.004
Y51 Drugs primarily affecting the autonomic nervous system
0.004 0.996 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.996 0.004
Y47 Sedatives, hypnotics and antianxiety drugs
0.004 0.996 0.000
Y54.9 Mineral salts, not elsewhere classified
0.004 0.996 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.004 0.996 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.004 0.996 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.004 0.996 0.000
Y54.5 Other diuretics
0.004 0.996 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.996 0.004
Y54.7 Agents affecting calcification
0.004 0.996 0.000
N00.8 Other
0.000 0.996 0.004
N00.7 Diffuse crescentic glomerulonephritis
0.000 0.996 0.004
N00.6 Dense deposit disease
0.000 0.996 0.004
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.996 0.004
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.996 0.004
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.996 0.004
N00.2 Diffuse membranous glomerulonephritis
0.000 0.996 0.004
N00.1 Focal and segmental glomerular lesions
0.000 0.996 0.004
N00.0 Minor glomerular abnormality
0.000 0.996 0.004
Y46 Antiepileptics and anti-Parkinsonism drugs
0.004 0.996 0.000
G83.3 Monoplegia, unspecified
0.000 0.996 0.004
Y44.5 Thrombolytic drugs
0.004 0.996 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.004 0.996 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.004 0.996 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.004 0.996 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.004 0.996 0.000
Y44.7 Plasma substitutes
0.004 0.996 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.004 0.996 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.996 0.004
G83.5 Locked-in syndrome
0.000 0.996 0.004
G83.0 Diplegia of upper limbs
0.000 0.996 0.004
Y48 Anaesthetics and therapeutic gases
0.004 0.996 0.000
G83.9 Paralytic syndrome, unspecified
0.000 0.996 0.004
C02.1 Border of tongue
0.000 0.996 0.004
N00.9 Unspecified
0.000 0.996 0.004
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.004 0.996 0.000
Y59 Other and unspecified vaccines and biological substances
0.004 0.996 0.000
Y44.6 Natural blood and blood products
0.004 0.996 0.000
H25.0 Senile incipient cataract
0.000 0.996 0.004
D89.1 Cryoglobulinaemia
0.000 0.996 0.004
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.996 0.004
Y53.6 Antidiarrhoeal drugs
0.004 0.996 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.004 0.996 0.000
G83.2 Monoplegia of upper limb
0.000 0.996 0.004
I45.1 Other and unspecified right bundle-branch block
0.004 0.996 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.004 0.996 0.000
D68.8 Other specified coagulation defects
0.004 0.996 0.000
Y49.2 Other and unspecified antidepressants
0.004 0.996 0.000
Y57.6 Other diagnostic agents
0.004 0.996 0.000
Z45 Adjustment and management of implanted device
0.000 0.996 0.004
Y49.5 Other antipsychotics and neuroleptics
0.004 0.996 0.000
N13 Obstructive and reflux uropathy
0.000 0.996 0.004
Y41.0 Sulphonamides
0.004 0.996 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.004 0.996 0.000
Y58.0 BCG vaccine
0.004 0.996 0.000
D68 Other coagulation defects
0.004 0.996 0.000
C02.4 Lingual tonsil
0.000 0.996 0.004
D69.6 Thrombocytopenia, unspecified
0.004 0.996 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.004 0.996 0.000
Y57.7 Vitamins, not elsewhere classified
0.004 0.996 0.000
Y57.4 Pharmaceutical excipients
0.004 0.996 0.000
Y57.3 Alcohol deterrents
0.004 0.996 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.004 0.996 0.000
Y57.1 Lipotropic drugs
0.004 0.996 0.000
Y57.0 Appetite depressants [anorectics]
0.004 0.996 0.000
Y50.2 Methylxanthines, not elsewhere classified
0.003 0.996 0.000
Y53.2 Stimulant laxatives
0.003 0.996 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.003 0.996 0.000
Y53.7 Emetics
0.003 0.996 0.000
Y53.5 Digestants
0.003 0.996 0.000
Y53.0 Histamine H2-receptor antagonists
0.003 0.996 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.996 0.004
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.996 0.004
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.004 0.996 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.003 0.996 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.003 0.996 0.000
Y58.9 Other and unspecified bacterial vaccines
0.003 0.996 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.003 0.996 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.003 0.996 0.000
Y58.5 Diphtheria vaccine
0.003 0.996 0.000
Y58.4 Tetanus vaccine
0.003 0.996 0.000
Y58.3 Plague vaccine
0.003 0.996 0.000
Y58.2 Cholera vaccine
0.003 0.996 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.003 0.996 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.996 0.003
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.003 0.996 0.000
Y41.4 Anthelminthics
0.003 0.996 0.000
Y41.3 Other antiprotozoal drugs
0.003 0.996 0.000
Y46.7 Anti-Parkinsonism drugs
0.003 0.996 0.000
Y49.9 Psychotropic drug, unspecified
0.003 0.996 0.000
Y49.7 Psychostimulants with abuse potential
0.003 0.996 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.003 0.996 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.003 0.996 0.000
Y50.9 Central nervous system stimulant, unspecified
0.003 0.996 0.000
Y50.8 Other central nervous system stimulants
0.003 0.996 0.000
Y50.1 Opioid receptor antagonists
0.003 0.996 0.000
Y50.0 Analeptics
0.003 0.996 0.000
C02.2 Ventral surface of tongue
0.000 0.996 0.003
Y53.4 Other laxatives
0.003 0.996 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.996 0.004
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.003 0.996 0.000
Y57.8 Other drugs and medicaments
0.003 0.996 0.000
Y41.1 Antimycobacterial drugs
0.003 0.996 0.000
C02.0 Dorsal surface of tongue
0.000 0.997 0.003
G83.8 Other specified paralytic syndromes
0.000 0.997 0.003
Y53.3 Saline and osmotic laxatives
0.003 0.997 0.000
Y54.3 Benzothiadiazine derivatives
0.003 0.997 0.000
D68.9 Coagulation defect, unspecified
0.003 0.997 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.003 0.997 0.000
D68.5 Primary Thrombophilia
0.003 0.997 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.003 0.997 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.997 0.003
Y49.8 Other psychotropic drugs, not elsewhere classified
0.003 0.997 0.000
N18.5 Chronic kidney disease, stage 5
0.000 0.997 0.003
D68.2 Hereditary deficiency of other clotting factors
0.003 0.997 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.997 0.003
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.003 0.997 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.003 0.997 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.003 0.997 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.003 0.997 0.000
Y51.0 Anticholinesterase agents
0.003 0.997 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.997 0.003
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.997 0.003
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.003 0.997 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.003 0.997 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.003 0.997 0.000
Y47.4 Bromine compounds
0.003 0.997 0.000
Y47.3 Paraldehyde
0.003 0.997 0.000
Y47.2 Chloral derivatives
0.003 0.997 0.000
Y47.0 Barbiturates, not elsewhere classified
0.003 0.997 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.997 0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.003 0.997 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.997 0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.003 0.997 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.003 0.997 0.000
Y46.8 Antispasticity drugs
0.003 0.997 0.000
Y46.3 Deoxybarbiturates
0.003 0.997 0.000
Y46.1 Oxazolidinediones
0.003 0.997 0.000
Y46.0 Succinimides
0.003 0.997 0.000
Y56.9 Topical agent, unspecified
0.003 0.997 0.000
Y56.8 Other topical agents
0.003 0.997 0.000
Y56.7 Dental drugs, topically applied
0.003 0.997 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.003 0.997 0.000
Y56.5 Ophthalmological drugs and preparations
0.003 0.997 0.000
Y56.3 Emollients, demulcents and protectants
0.003 0.997 0.000
Y56.2 Local astringents and local detergents
0.003 0.997 0.000
Y56.1 Antipruritics
0.003 0.997 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.997 0.003
Y48.2 Other and unspecified general anaesthetics
0.003 0.997 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.003 0.997 0.000
C02.8 Overlapping lesion of tongue
0.000 0.997 0.003
D89.3 Immune reconstitution syndrome
0.000 0.997 0.003
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.997 0.003
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.003 0.997 0.000
Y55.5 Anticommon cold drugs
0.003 0.997 0.000
Y55.3 Antitussives
0.003 0.997 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.003 0.997 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.997 0.003
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.997 0.003
Y55.4 Expectorants
0.003 0.997 0.000
Y46.2 Hydantoin derivatives
0.003 0.997 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.997 0.003
Y41.5 Antiviral drugs
0.003 0.997 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.003 0.997 0.000
Y46.5 Valproic acid
0.003 0.997 0.000
Y48.5 Therapeutic gases
0.003 0.997 0.000
Y48.1 Parenteral anaesthetics
0.003 0.997 0.000
Y48.0 Inhaled anaesthetics
0.003 0.997 0.000
T82.3 Mechanical complication of other vascular grafts
0.000 0.997 0.003
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.003 0.997 0.000
Y46.6 Other and unspecified antiepileptics
0.003 0.997 0.000
N10-N16 Renal tubulo-interstitial diseases
0.000 0.997 0.003
N18.0 End-stage renal disease
0.000 0.997 0.003
Y59.9 Vaccine or biological substance, unspecified
0.003 0.997 0.000
Y59.8 Other specified vaccines and biological substances
0.003 0.997 0.000
Y59.2 Protozoal vaccines
0.003 0.997 0.000
Y59.1 Rickettsial vaccines
0.003 0.997 0.000
N11 Chronic tubulo-interstitial nephritis
0.000 0.997 0.003
Y47.1 Benzodiazepines
0.003 0.997 0.000
Z45.3 Adjustment and management of implanted hearing device
0.000 0.997 0.003
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.997 0.003
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.000 0.997 0.003
Y55.0 Oxytocic drugs
0.003 0.997 0.000
N18 Chronic renal failure
0.000 0.997 0.003
D68.0 Von Willebrand's disease
0.003 0.997 0.000
Y59.0 Viral vaccines
0.003 0.997 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.003 0.997 0.000
Y48.4 Anaesthetic, unspecified
0.003 0.997 0.000
N75.0 Cyst of Bartholin's gland
0.003 0.997 0.000
Y46.4 Iminostilbenes
0.003 0.997 0.000
N13.4 Hydroureter
0.000 0.997 0.003
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.003 0.997 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.000 0.997 0.003
Q63.0 Accessory kidney
0.003 0.997 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.003 0.997 0.000
D82.1 Di George's syndrome
0.000 0.997 0.003
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.997 0.003
N70.1 Chronic salpingitis and oophoritis
0.003 0.997 0.000
Y42.1 Thyroid hormones and substitutes
0.003 0.997 0.000
D81 Combined immunodeficiencies
0.000 0.997 0.003
D69 Purpura and other haemorrhagic conditions
0.003 0.997 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.997 0.003
T82.1 Mechanical complication of cardiac electronic device
0.000 0.997 0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.003 0.997 0.000
C05 Malignant neoplasm of palate
0.000 0.997 0.003
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.000 0.997 0.003
N18.4 Chronic kidney disease, stage 4
0.000 0.997 0.003
Y40 Systemic antibiotics
0.003 0.997 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.003 0.997 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.997 0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.002 0.997 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.997 0.003
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.000 0.997 0.003
Y59.3 Immunoglobulin
0.002 0.997 0.000
Y48.3 Local anaesthetics
0.003 0.997 0.000
C05.1 Soft palate
0.000 0.997 0.003
D69.4 Other primary thrombocytopenia
0.003 0.997 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.997 0.003
D83 Common variable immunodeficiency
0.000 0.997 0.003
D68.4 Acquired coagulation factor deficiency
0.003 0.997 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.997 0.003
Y42.9 Other and unspecified hormone antagonists
0.003 0.997 0.000
D68.1 Hereditary factor XI deficiency
0.003 0.997 0.000
Y42.4 Oral contraceptives
0.003 0.997 0.000
D68.6 Other Thrombophilia
0.003 0.997 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.003 0.997 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.997 0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.003 0.997 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.000 0.997 0.002
N15 Other renal tubulo-interstitial diseases
0.000 0.997 0.003
Y42.2 Antithyroid drugs
0.002 0.997 0.000
C01 Malignant neoplasm of base of tongue
0.000 0.997 0.003
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.000 0.997 0.003
Y40.7 Antifungal antibiotics, systemically used
0.003 0.997 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.002 0.997 0.000
Y57.5 X-ray contrast media
0.002 0.997 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.997 0.002
T82.4 Mechanical complication of vascular dialysis catheter
0.000 0.997 0.003
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.997 0.002
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.997 0.002
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.997 0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.997 0.002
D82.2 Immunodeficiency with short-limbed stature
0.000 0.997 0.002
D82.0 Wiskott-Aldrich syndrome
0.000 0.997 0.002
N13.6 Pyonephrosis
0.000 0.997 0.002
C00 Malignant neoplasm of lip
0.000 0.997 0.002
G80 Infantile cerebral palsy
0.000 0.997 0.002
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.000 0.997 0.002
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.997 0.002
N11.8 Other chronic tubulo-interstitial nephritis
0.000 0.997 0.002
N13.8 Other obstructive and reflux uropathy
0.000 0.997 0.002
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.997 0.002
C04 Malignant neoplasm of floor of mouth
0.000 0.997 0.002
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.997 0.002
C08.9 Major salivary gland, unspecified
0.000 0.998 0.002
H02.1 Ectropion of eyelid
0.002 0.998 0.000
N11.1 Chronic obstructive pyelonephritis
0.000 0.998 0.002
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.000 0.998 0.002
M89.0 Algoneurodystrophy
0.002 0.998 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.000 0.998 0.002
D84 Other immunodeficiencies
0.000 0.998 0.002
C05.9 Palate, unspecified
0.000 0.998 0.002
C00.0 External upper lip
0.000 0.998 0.002
C05.0 Hard palate
0.000 0.998 0.002
D69.0 Allergic purpura
0.002 0.998 0.000
Y40.9 Systemic antibiotic, unspecified
0.002 0.998 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.002 0.998 0.000
C13 Malignant neoplasm of hypopharynx
0.000 0.998 0.002
M89.04 Algoneurodystrophy (Hand)
0.002 0.998 0.000
M89.03 Algoneurodystrophy (Forearm)
0.002 0.998 0.000
C04.9 Floor of mouth, unspecified
0.000 0.998 0.002
Y40.5 Aminoglycosides
0.002 0.998 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.998 0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.000 0.998 0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.998 0.002
D69.2 Other nonthrombocytopenic purpura
0.002 0.998 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.998 0.002
D81.8 Other combined immunodeficiencies
0.000 0.998 0.002
D81.7 Major histocompatibility complex class II deficiency
0.000 0.998 0.002
D81.6 Major histocompatibility complex class I deficiency
0.000 0.998 0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.998 0.002
D81.4 Nezelof's syndrome
0.000 0.998 0.002
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.998 0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.998 0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.998 0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.998 0.002
N18.1 Chronic kidney disease, stage 1
0.000 0.998 0.002
Y42.5 Other oestrogens and progestogens
0.002 0.998 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.998 0.002
D69.3 Idiopathic thrombocytopenic purpura
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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