TreeWAS – Variant ID: rs4487645

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C90.0 Multiple myeloma	0.000	0.005	0.995
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.258	0.742
C90.1 Plasma cell leukaemia	0.000	0.385	0.615
C90.3 Solitary plasmacytoma	0.000	0.435	0.564
C90.2 Plasmacytoma, extramedullary	0.000	0.485	0.515
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.586	0.414
C92 Myeloid leukaemia	0.000	0.590	0.410
C92.1 Chronic myeloid leukaemia	0.000	0.606	0.394
C81 Hodgkin's disease	0.000	0.608	0.392
C92.0 Acute myeloid leukaemia	0.000	0.612	0.388
C81.1 Nodular sclerosis	0.000	0.646	0.354
C81.0 Lymphocytic predominance	0.000	0.681	0.319
C92.9 Myeloid leukaemia, unspecified	0.000	0.683	0.317
C81.2 Mixed cellularity	0.000	0.687	0.313
C86 Other specified types of T/NK-cell lymphoma	0.000	0.697	0.302
C81.9 Hodgkin's disease, unspecified	0.000	0.702	0.298
C92.7 Other myeloid leukaemia	0.000	0.702	0.297
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.703	0.297
C94 Other leukaemias of specified cell type	0.000	0.703	0.297
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.706	0.294
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.706	0.294
C92.5 Acute myelomonocytic leukaemia	0.000	0.706	0.294
C92.3 Myeloid sarcoma	0.000	0.706	0.294
C92.2 Subacute myeloid leukaemia	0.000	0.706	0.294
C93 Monocytic leukaemia	0.000	0.713	0.287
C95 Leukaemia of unspecified cell type	0.000	0.717	0.283
C81.7 Other Hodgkin's disease	0.000	0.718	0.281
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.718	0.281
C81.3 Lymphocytic depletion	0.000	0.718	0.281
C91 Lymphoid leukaemia	0.000	0.728	0.272
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.759	0.241
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.777	0.222
C92.4 Acute promyelocytic leukaemia	0.000	0.778	0.222
C91.0 Acute lymphoblastic leukaemia	0.000	0.783	0.217
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.783	0.217
C86.4 Blastic NK-cell lymphoma	0.000	0.783	0.217
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.783	0.217
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.783	0.217
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.783	0.217
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.783	0.217
C94.7 Other specified leukaemias	0.000	0.787	0.213
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.787	0.213
C94.5 Acute myelofibrosis	0.000	0.787	0.213
C94.4 Acute panmyelosis	0.000	0.787	0.213
C94.3 Mast cell leukaemia	0.000	0.787	0.213
C94.2 Acute megakaryoblastic leukaemia	0.000	0.787	0.213
C94.1 Chronic erythraemia	0.000	0.787	0.213
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.787	0.213
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.787	0.213
C96.8 Histiocytic sarcoma	0.000	0.787	0.213
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.787	0.213
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.787	0.213
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.787	0.213
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.787	0.213
C96.3 True histiocytic lymphoma	0.000	0.787	0.213
C96.2 Malignant mast cell tumour	0.000	0.787	0.213
C96.1 Malignant histiocytosis	0.000	0.787	0.213
C96.0 Letterer-Siwe disease	0.000	0.787	0.213
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.788	0.212
C88 Malignant immunoproliferative diseases	0.001	0.790	0.209
C93.9 Monocytic leukaemia, unspecified	0.000	0.794	0.206
C93.7 Other monocytic leukaemia	0.000	0.794	0.206
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.794	0.206
C93.2 Subacute monocytic leukaemia	0.000	0.794	0.206
C93.0 Acute monocytic leukaemia	0.000	0.794	0.206
C95.7 Other leukaemia of unspecified cell type	0.000	0.797	0.203
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.797	0.203
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.797	0.203
C91.1 Chronic lymphocytic leukaemia	0.000	0.798	0.202
C91.9 Lymphoid leukaemia, unspecified	0.000	0.798	0.202
C95.0 Acute leukaemia of unspecified cell type	0.000	0.799	0.201
C93.1 Chronic monocytic leukaemia	0.000	0.804	0.195
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.805	0.195
C91.7 Other lymphoid leukaemia	0.000	0.805	0.195
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.805	0.195
C91.3 Prolymphocytic leukaemia	0.000	0.805	0.195
C91.2 Subacute lymphocytic leukaemia	0.000	0.805	0.195
C84.4 Peripheral T-cell lymphoma	0.000	0.807	0.193
C95.9 Leukaemia, unspecified	0.000	0.808	0.191
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.827	0.173
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.827	0.173
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.827	0.173
C84.3 Lymphoepithelioid lymphoma	0.000	0.827	0.173
C84.2 T-zone lymphoma	0.000	0.827	0.173
C84.1 Sezary's diease	0.000	0.827	0.173
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.832	0.168
C82.0 Small cleaved cell, follicular	0.000	0.835	0.165
C84.0 Mycosis fungoides	0.000	0.835	0.165
C91.4 Hairy-cell leukaemia	0.000	0.840	0.160
C82.3 Follicular lymphoma grade IIIa	0.000	0.845	0.155
C91.5 Adult T-cell leukaemia	0.000	0.846	0.154
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.847	0.153
C82.6 Cutaneous follicle centre lymphoma	0.000	0.848	0.152
C82.5 Diffuse follicle centre lymphoma	0.000	0.848	0.152
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.848	0.151
C88.9 Malignant immunoproliferative disease, unspecified	0.001	0.850	0.150
C88.7 Other malignant immunoproliferative diseases	0.001	0.850	0.150
C88.3 Immunoproliferative small intestinal disease	0.001	0.850	0.150
C88.2 Gamma heavy chain disease	0.001	0.850	0.150
C88.1 Alpha heavy chain disease	0.001	0.850	0.150
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.853	0.147
C82.4 Follicular lymphoma grade IIIb	0.000	0.864	0.135
C82.2 Large cell, follicular	0.000	0.873	0.127
C84.5 Other and unspecified T-cell lymphomas	0.000	0.878	0.121
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.922	0.078
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.002	0.929	0.069
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.936	0.064
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.944	0.056
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.947	0.052
C85.0 Lymphosarcoma	0.000	0.951	0.048
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.971	0.029
Z80.0 Family history of malignant neoplasm of digestive organs	0.024	0.976	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.978	0.022
C83.6 Undifferentiated (diffuse)	0.000	0.979	0.021
C83.5 Lymphoblastic (diffuse)	0.000	0.979	0.021
C83.4 Immunoblastic (diffuse)	0.000	0.979	0.021
C83.2 Mixed small and large cell (diffuse)	0.000	0.982	0.018
H61.0 Perichondritis of external ear	0.018	0.982	0.000
H61.3 Acquired stenosis of external ear canal	0.017	0.983	0.000
H61 Other disorders of external ear	0.017	0.983	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.983	0.016
H61.8 Other specified disorders of external ear	0.016	0.984	0.000
C83.7 Burkitt's tumour	0.001	0.984	0.015
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.984	0.015
C85.1 B-cell lymphoma, unspecified	0.000	0.984	0.015
C83.0 Small cell (diffuse)	0.000	0.985	0.014
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.985	0.014
I63.8 Other cerebral infarction	0.014	0.986	0.000
H61.9 Disorder of external ear, unspecified	0.014	0.986	0.000
C83.3 Large cell (diffuse)	0.000	0.987	0.013
H61.1 Non-infective disorders of pinna	0.013	0.987	0.000
K61.0 Anal abscess	0.011	0.989	0.000
C71.9 Brain, unspecified	0.010	0.990	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.991	0.009
C71 Malignant neoplasm of brain	0.009	0.991	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.992	0.008
C71.4 Occipital lobe	0.007	0.992	0.000
C71.7 Brain stem	0.007	0.993	0.000
C71.0 Cerebrum, except lobes and ventricles	0.007	0.993	0.000
H60-H62 Diseases of external ear	0.007	0.993	0.000
C71.2 Temporal lobe	0.007	0.993	0.000
C71.1 Frontal lobe	0.007	0.993	0.000
C71.6 Cerebellum	0.007	0.993	0.000
C71.8 Overlapping lesion of brain	0.007	0.993	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
H61.2 Impacted cerumen	0.006	0.994	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.994	0.006
K05.3 Chronic periodontitis	0.000	0.994	0.006
H62 Disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
C71.3 Parietal lobe	0.006	0.994	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.995	0.005
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.995	0.005
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.005	0.995	0.000
K61 Abscess of anal and rectal regions	0.005	0.995	0.000
C21.1 Anal canal	0.005	0.995	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H62.2 Otitis externa in mycoses	0.004	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.995	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.996	0.004
R90.0 Intracranial space-occupying lesion	0.004	0.996	0.000
K61.2 Anorectal abscess	0.004	0.996	0.000
H60 Otitis externa	0.004	0.996	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.996	0.004
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.004	0.996	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.996	0.004
K61.1 Rectal abscess	0.004	0.996	0.000
H60.1 Cellulitis of external ear	0.004	0.996	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.996	0.004
M25.51 Pain in joint (Shoulder region)	0.004	0.996	0.000
J37.0 Chronic laryngitis	0.000	0.996	0.004
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.996	0.004
T18.5 Foreign body in anus and rectum	0.004	0.996	0.000
K61.4 Intrasphincteric abscess	0.004	0.996	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.996	0.004
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.996	0.004
K60.3 Anal fistula	0.004	0.996	0.000
C70 Malignant neoplasm of meninges	0.004	0.996	0.000
C21 Malignant neoplasm of anus and anal canal	0.004	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
C21.0 Anus, unspecified	0.003	0.996	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
H60.5 Acute otitis externa, non-infective	0.003	0.997	0.000
D37.5 Rectum	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.003	0.997	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
C70.0 Cerebral meninges	0.003	0.997	0.000
K60.1 Chronic anal fissure	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
H60.0 Abscess of external ear	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
N81.4 Uterovaginal prolapse, unspecified	0.000	0.997	0.003
C72.0 Spinal cord	0.003	0.997	0.000
O48 Prolonged pregnancy	0.000	0.997	0.003
C70.9 Meninges, unspecified	0.003	0.997	0.000
C70.1 Spinal meninges	0.003	0.997	0.000
C21.2 Cloacogenic zone	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
T17.5 Foreign body in bronchus	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
C72.9 Central nervous system, unspecified	0.003	0.997	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.003	0.997	0.000
C72.5 Other and unspecified cranial nerves	0.003	0.997	0.000
C72.4 Acoustic nerve	0.003	0.997	0.000
C72.3 Optic nerve	0.003	0.997	0.000
C72.2 Olfactory nerve	0.003	0.997	0.000
C72.1 Cauda equina	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
K61.3 Ischiorectal abscess	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
W50.9 Unspecified place	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.997	0.003
D83.8 Other common variable immunodeficiencies	0.002	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.997	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.997	0.000
D81 Combined immunodeficiencies	0.002	0.997	0.000
T18 Foreign body in alimentary tract	0.002	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
K05 Gingivitis and periodontal diseases	0.000	0.998	0.002
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
D01.3 Anus and anal canal	0.002	0.998	0.000
D30.0 Kidney	0.002	0.998	0.000
K05.0 Acute gingivitis	0.000	0.998	0.002
K60 Fissure and fistula of anal and rectal regions	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.001
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
C69.0 Conjunctiva	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.000	0.998	0.002
F43.0 Acute stress reaction	0.000	0.998	0.002
K05.5 Other periodontal diseases	0.000	0.998	0.002
T18.3 Foreign body in small intestine	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
H52.0 Hypermetropia	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
R23.2 Flushing	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
M25.31 Other instability of joint (Shoulder region)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.002	0.998	0.000
T18.4 Foreign body in colon	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
C69.3 Choroid	0.002	0.998	0.000
K05.2 Acute periodontitis	0.000	0.998	0.002
K05.4 Periodontosis	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
T18.0 Foreign body in mouth	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
W06.0 Home	0.000	0.998	0.002
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998	0.000
C69.9 Eye, unspecified	0.002	0.998	0.000
E10.9 Without complications	0.002	0.998	0.000
F43.2 Adjustment disorders	0.000	0.998	0.002
S82.3 Fracture of lower end of tibia	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
K60.4 Rectal fistula	0.002	0.998	0.000
T18.2 Foreign body in stomach	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.001
D89.3 Immune reconstitution syndrome	0.001	0.998	0.001
T16 Foreign body in ear	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
Z88.6 Personal history of allergy to analgesic agent	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
K05.1 Chronic gingivitis	0.000	0.998	0.002
T17.4 Foreign body in trachea	0.002	0.998	0.000
T17.1 Foreign body in nostril	0.002	0.998	0.000
T17.0 Foreign body in nasal sinus	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.000	0.998	0.002
S82.0 Fracture of patella	0.000	0.998	0.002
T17.3 Foreign body in larynx	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
T17.8 Foreign body in other and multiple parts of respiratory tract	0.002	0.998	0.000
T15 Foreign body on external eye	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
D01.2 Rectum	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.001
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
U88 Agent resistant to multiple antibiotics	0.000	0.998	0.002
F43.8 Other reactions to severe stress	0.000	0.998	0.002
X49.9 Unspecified place	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.002
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.002	0.998	0.000
K05.22 Aggressive periodontitis, generalized	0.000	0.998	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.002
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.002
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.002
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.002
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
L65.9 Nonscarring hair loss, unspecified	0.000	0.998	0.002
J37 Chronic laryngitis and laryngotracheitis	0.000	0.998	0.002
A63.8 Other specified predominantly sexually transmitted diseases	0.002	0.998	0.000
T15.0 Foreign body in cornea	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.001
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
T19 Foreign body in genito-urinary tract	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
K60.2 Anal fissure, unspecified	0.002	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.002	0.998	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.002	0.998	0.000
D44.3 Pituitary gland	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
D44.0 Thyroid gland	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.002	0.998	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.998	0.000
W50.0 Home	0.001	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.001
K60.5 Anorectal fistula	0.001	0.998	0.000
T15.8 Foreign body in other and multiple parts of external eye	0.001	0.998	0.000
T15.1 Foreign body in conjunctival sac	0.001	0.998	0.000
W50.8 Other specified place	0.001	0.998	0.000
K60.0 Acute anal fissure	0.001	0.998	0.000
T15.9 Foreign body on external eye, unspecified	0.001	0.998	0.000
W50.3 Sports and athletics area	0.001	0.998	0.000
W50.7 Farm	0.001	0.998	0.000
W50.6 Industrial and construction area	0.001	0.998	0.000
W50.5 Trade and service area	0.001	0.998	0.000
W50.2 School, other institution and public administrative area	0.001	0.998	0.000
W50.1 Residential institution	0.001	0.998	0.000
S81 Open wound of lower leg	0.000	0.998	0.002
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.001
D01.0 Colon	0.001	0.998	0.000
J37.1 Chronic laryngotracheitis	0.000	0.998	0.001
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
W50.4 Street and highway	0.001	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.001
X69.9 Unspecified place	0.001	0.998	0.000
R06.8 Other and unspecified abnormalities of breathing	0.001	0.999	0.000
T19.1 Foreign body in bladder	0.001	0.999	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.999	0.001
U84 Resistance to other antimicrobial drugs	0.000	0.999	0.001
U83 Resistance to other antibiotics	0.000	0.999	0.001
U82 Resistance to betalactam antibiotics	0.000	0.999	0.001
U85 Resistance to antineoplastic drugs	0.000	0.999	0.001
S82.5 Fracture of medial malleolus	0.001	0.999	0.000
M06.34 Rheumatoid nodule (Hand)	0.001	0.999	0.000
M71.96 Bursopathy, unspecified (Lower leg)	0.001	0.999	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.999	0.001
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.999	0.001
T19.9 Foreign body in genito-urinary tract, part unspecified	0.001	0.999	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.001	0.999	0.000
T19.3 Foreign body in uterus [any part]	0.001	0.999	0.000
T19.0 Foreign body in urethra	0.001	0.999	0.000
D68 Other coagulation defects	0.000	0.999	0.001
R90 Abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
D01.9 Digestive organ, unspecified	0.001	0.999	0.000
D01.7 Other specified digestive organs	0.001	0.999	0.000
D01.5 Liver, gallbladder and bile ducts	0.001	0.999	0.000
D01.4 Other and unspecified parts of intestine	0.001	0.999	0.000
D01.1 Rectosigmoid junction	0.001	0.999	0.000
X69.0 Home	0.001	0.999	0.000
S32.4 Fracture of acetabulum	0.000	0.999	0.001
W50.30 Hit, struck, kicked, twisted, bitten or scratched by another person; Sports and athletics area;While engaged in sports activity	0.001	0.999	0.000
S82.4 Fracture of fibula alone	0.000	0.999	0.001
M47.99 Spondylosis, unspecified (Site unspecified)	0.001	0.999	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.999	0.001
H81.0 Meniere's disease	0.001	0.999	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.999	0.001
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.001	0.999	0.000
S82.51 Fracture of medial malleolus (open)	0.001	0.999	0.000
N05.9 Unspecified	0.001	0.999	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.999	0.001
U82.8 Resistance to other betalactam antibiotics	0.000	0.999	0.001
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.999	0.001
U82.1 Resistance to methicillin	0.000	0.999	0.001
U82.0 Resistance to penicillin	0.000	0.999	0.001
U83.9 Resistance to unspecified antibiotic	0.000	0.999	0.001
U83.8 Resistance to other single specified antibiotic	0.000	0.999	0.001
U83.7 Resistance to multiple antibiotics	0.000	0.999	0.001
U83.2 Resistance to quinolones	0.000	0.999	0.001
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.999	0.001
U83.0 Resistance to vancomycin	0.000	0.999	0.001
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.999	0.001
U84.8 Resistance to other specified antimicrobial drug	0.000	0.999	0.001
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.999	0.001
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.999	0.001
U84.2 Resistance to antiviral drug(s)	0.000	0.999	0.001
U84.1 Resistance to antifungal drug(s)	0.000	0.999	0.001
U84.0 Resistance to antiparasitic drug(s)	0.000	0.999	0.001
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.001	0.999	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.999	0.001
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
K05.6 Periodontal disease, unspecified	0.000	0.999	0.001
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
H60.9 Otitis externa, unspecified	0.001	0.999	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
T19.2 Foreign body in vulva and vagina	0.001	0.999	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
M71.95 Bursopathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S32.41 Fracture of acetabulum (open)	0.000	0.999	0.001
S00.3 Superficial injury of nose	0.001	0.999	0.000
H81 Disorders of vestibular function	0.001	0.999	0.000
M91.20 Coxa plana-Mult sites	0.000	0.999	0.001
S82.41 Fracture of fibula alone (open)	0.000	0.999	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.999	0.001
H81.3 Other peripheral vertigo	0.001	0.999	0.000
X63.0 Home	0.001	0.999	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.999	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.999	0.001
J95.0 Tracheostomy malfunction	0.000	0.999	0.001
X60.8 Other specified place	0.001	0.999	0.000
X69.8 Other specified place	0.001	0.999	0.000
X69.7 Farm	0.001	0.999	0.000
X69.6 Industrial and construction area	0.001	0.999	0.000
X69.5 Trade and service area	0.001	0.999	0.000
X69.4 Street and highway	0.001	0.999	0.000
X69.3 Sports and athletics area	0.001	0.999	0.000
X69.2 School, other institution and public administrative area	0.001	0.999	0.000
X69.1 Residential institution	0.001	0.999	0.000
Z29.2 Other prophylactic chemotherapy	0.001	0.999	0.000
G03.9 Meningitis, unspecified	0.000	0.999	0.001
M71.9 Bursopathy, unspecified	0.001	0.999	0.000
S32.5 Fracture of pubis	0.000	0.999	0.001
Y76.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations