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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4504471
log Bayes Factor = 15.5536
Chromosome 6   position 27,372,242  (GRCh37) Explore rs4504471 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.598 0.402
E10.9 Without complications
0.000 0.603 0.397
E10.4 With neurological complications
0.000 0.627 0.373
E10.5 With peripheral circulatory complications
0.000 0.629 0.371
E10.6 With other specified complications
0.000 0.637 0.363
E10.8 With unspecified complications
0.000 0.661 0.339
E10-E14 Diabetes mellitus
0.000 0.686 0.314
E10.1 With ketoacidosis
0.000 0.698 0.302
E10.2 With renal complications
0.000 0.700 0.300
K90 Intestinal malabsorption
0.000 0.711 0.289
E10.7 With multiple complications
0.000 0.712 0.288
E83 Disorders of mineral metabolism
0.000 0.721 0.279
E10.0 With coma
0.000 0.727 0.273
E13 Other specified diabetes mellitus
0.000 0.734 0.266
E10.3 With ophthalmic complications
0.000 0.744 0.256
E14 Unspecified diabetes mellitus
0.000 0.756 0.244
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.763 0.237
E70-E90 Metabolic disorders
0.000 0.766 0.234
E13.9 Without complications
0.000 0.766 0.234
E14.3 With ophthalmic complications
0.000 0.766 0.234
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.768 0.232
E12 Malnutrition-related diabetes mellitus
0.000 0.775 0.225
K90.3 Pancreatic steatorrhoea
0.000 0.792 0.208
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.792 0.208
K90.1 Tropical sprue
0.000 0.792 0.208
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.793 0.207
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.800 0.200
E83.8 Other disorders of mineral metabolism
0.000 0.800 0.200
E83.2 Disorders of zinc metabolism
0.000 0.800 0.200
E83.0 Disorders of copper metabolism
0.000 0.800 0.200
K90.8 Other intestinal malabsorption
0.000 0.800 0.200
E40-E46 Malnutrition
0.000 0.801 0.199
E88 Other metabolic disorders
0.000 0.802 0.198
E13.8 With unspecified complications
0.000 0.809 0.191
E13.7 With multiple complications
0.000 0.809 0.191
E13.6 With other specified complications
0.000 0.809 0.191
E13.5 With peripheral circulatory complications
0.000 0.809 0.191
E13.4 With neurological complications
0.000 0.809 0.191
E13.2 With renal complications
0.000 0.809 0.191
E13.1 With ketoacidosis
0.000 0.809 0.191
E13.0 With coma
0.000 0.809 0.191
E85 Amyloidosis
0.000 0.810 0.190
E13.3 With ophthalmic complications
0.000 0.813 0.187
E16 Other disorders of pancreatic internal secretion
0.000 0.814 0.186
E14.5 With peripheral circulatory complications
0.000 0.818 0.182
E16.2 Hypoglycaemia, unspecified
0.000 0.824 0.176
E14.7 With multiple complications
0.000 0.825 0.175
E14.6 With other specified complications
0.000 0.825 0.175
E14.2 Withrenal complications
0.000 0.825 0.175
E14.0 With coma
0.000 0.825 0.175
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.826 0.174
E46 Unspecified protein-energy malnutrition
0.000 0.828 0.172
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.828 0.172
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.830 0.170
E14.4 With neurological complications
0.000 0.831 0.169
E84 Cystic fibrosis
0.000 0.832 0.168
E77 Disorders of glycoprotein metabolism
0.000 0.832 0.168
E76 Disorders of glycosaminoglycan metabolism
0.000 0.832 0.168
E72 Other disorders of amino-acid metabolism
0.000 0.832 0.168
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.832 0.168
E70 Disorders of aromatic amino-acid metabolism
0.000 0.832 0.168
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.832 0.168
E65-E68 Obesity and other hyperalimentation
0.000 0.838 0.162
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.838 0.162
E12.9 Without complications
0.000 0.838 0.162
E12.8 With unspecified complications
0.000 0.838 0.162
E12.7 With multiple complications
0.000 0.838 0.162
E12.6 With other specified complications
0.000 0.838 0.162
E12.5 With peripheral circulatory complications
0.000 0.838 0.162
E12.4 With neurological complications
0.000 0.838 0.162
E12.3 With ophthalmic complications
0.000 0.838 0.162
E12.2 With renal complications
0.000 0.838 0.162
E12.1 With ketoacidosis
0.000 0.838 0.162
E12.0 With coma
0.000 0.838 0.162
E85.9 Amyloidosis, unspecified
0.000 0.841 0.159
E79 Disorders of purine and pyrimidine metabolism
0.000 0.848 0.152
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.849 0.151
E88.8 Other specified metabolic disorders
0.000 0.849 0.151
E88.2 Lipomatosis, not elsewhere classified
0.000 0.850 0.149
E15 Nondiabetic hypoglycaemic coma
0.000 0.851 0.148
E14.1 With ketoacidosis
0.000 0.851 0.148
E11 Non-insulin-dependent diabetes mellitus
0.000 0.855 0.145
E14.8 With unspecified complications
0.000 0.855 0.145
E85.4 Organ-limited amyloidosis
0.000 0.856 0.144
E88.3 Tumour lysis syndrome
0.000 0.857 0.143
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.857 0.143
E45 Retarded development following protein-energy malnutrition
0.000 0.857 0.143
E43 Unspecified severe protein-energy malnutrition
0.000 0.857 0.143
E42 Marasmic kwashiorkor
0.000 0.857 0.143
E41 Nutritional marasmus
0.000 0.857 0.143
E40 Kwashiorkor
0.000 0.857 0.143
E89.2 Postprocedural hypoparathyroidism
0.000 0.859 0.140
E65 Localised adiposity
0.000 0.861 0.139
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.862 0.138
E85.8 Other amyloidosis
0.000 0.863 0.136
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.863 0.136
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.863 0.136
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.863 0.136
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.865 0.135
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.867 0.133
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.867 0.133
E16.4 Abnormal secretion of gastrin
0.000 0.867 0.133
E16.3 Increased secretion of glucagon
0.000 0.867 0.133
E74 Other disorders of carbohydrate metabolism
0.000 0.867 0.133
E80.4 Gilbert's syndrome
0.000 0.867 0.133
E88.9 Metabolic disorder, unspecified
0.000 0.867 0.132
E89.0 Postprocedural hypothyroidism
0.000 0.869 0.131
E89.4 Postprocedural ovarian failure
0.000 0.869 0.130
E85.3 Secondary systemic amyloidosis
0.000 0.873 0.127
E75.5 Other lipid storage disorders
0.000 0.873 0.127
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.875 0.125
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.875 0.125
E89.5 Postprocedural testicular hypofunction
0.000 0.875 0.125
E89.1 Postprocedural hypoinsulinaemia
0.000 0.875 0.125
E75.6 Lipid storage disorder, unspecified
0.000 0.877 0.123
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.877 0.123
E75.3 Sphingolipidosis, unspecified
0.000 0.877 0.123
E75.2 Other sphingolipidosis
0.000 0.877 0.123
E75.1 Other gangliosidosis
0.000 0.877 0.123
E75.0 GM2 gangliosidosis
0.000 0.877 0.123
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.878 0.122
E80.5 Crigler-Najjar syndrome
0.000 0.878 0.122
E80.3 Defects of catalase and peroxydase
0.000 0.878 0.122
E80.1 Porphyria cutanea tarda
0.000 0.878 0.122
E80.0 Hereditary erythropoietic porphyria
0.000 0.878 0.122
E73 Lactose intolerance
0.001 0.878 0.121
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.879 0.121
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.879 0.121
E70.3 Albinism
0.000 0.879 0.121
E70.2 Disorders of tyrosine metabolism
0.000 0.879 0.121
E70.1 Other hyperphenylalaninaemias
0.000 0.879 0.121
E70.0 Classical phenylketonuria
0.000 0.879 0.121
E71.3 Disorders of fatty-acid metabolism
0.000 0.879 0.121
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.879 0.121
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.879 0.121
E71.0 Maple-syrup-urine disease
0.000 0.879 0.121
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.879 0.121
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.879 0.121
E72.5 Disorders of glycine metabolism
0.000 0.879 0.121
E72.4 Disorders of ornithine metabolism
0.000 0.879 0.121
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.879 0.121
E72.2 Disorders of urea cycle metabolism
0.000 0.879 0.121
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.879 0.121
E72.0 Disorders of amino-acid transport
0.000 0.879 0.121
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.879 0.121
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.879 0.121
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.879 0.121
E76.2 Other mucopolysaccharidoses
0.000 0.879 0.121
E76.1 Mucopolysaccharidosis, type II
0.000 0.879 0.121
E76.0 Mucopolysaccharidosis, type I
0.000 0.879 0.121
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.879 0.121
E77.8 Other disorders of glycoprotein metabolism
0.000 0.879 0.121
E77.1 Defects in glycoprotein degradation
0.000 0.879 0.121
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.879 0.121
E84.9 Cystic fibrosis, unspecified
0.000 0.879 0.121
E84.8 Cystic fibrosis with other manifestations
0.000 0.879 0.121
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.879 0.121
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.879 0.121
E11.5 With peripheral circulatory complications
0.000 0.880 0.120
E83.3 Disorders of phosphorus metabolism
0.000 0.882 0.117
E80.2 Other porphyria
0.000 0.882 0.117
E67 Other hyperalimentation
0.000 0.883 0.117
E68 Sequelae of hyperalimentation
0.000 0.883 0.117
E80.6 Other disorders of bilirubin metabolism
0.000 0.884 0.116
E11.0 With coma
0.000 0.889 0.111
E00-E07 Disorders of thyroid gland
0.000 0.889 0.111
E83.4 Disorders of magnesium metabolism
0.000 0.890 0.110
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.890 0.109
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.890 0.109
E79.1 Lesch-Nyhan syndrome
0.000 0.890 0.109
E11.8 With unspecified complications
0.000 0.891 0.109
E11.1 With ketoacidosis
0.000 0.893 0.107
E11.7 With multiple complications
0.000 0.896 0.104
E44.1 Mild protein-energy malnutrition
0.000 0.897 0.102
E44.0 Moderate protein-energy malnutrition
0.000 0.897 0.102
E11.2 With renal complications
0.000 0.898 0.102
E16.1 Other hypoglycaemia
0.000 0.899 0.101
E11.4 With neurological complications
0.000 0.900 0.100
E11.6 With other specified complications
0.000 0.900 0.100
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.902 0.098
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.904 0.095
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.904 0.095
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.904 0.095
E74.2 Disorders of galactose metabolism
0.000 0.904 0.095
E74.1 Disorders of fructose metabolism
0.000 0.904 0.095
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.905 0.095
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.906 0.093
K90.9 Intestinal malabsorption, unspecified
0.001 0.910 0.090
E74.0 Glycogen storage disease
0.000 0.912 0.088
E73.8 Other lactose intolerance
0.001 0.912 0.087
E73.1 Secondary lactase deficiency
0.001 0.912 0.087
E73.0 Congenital lactase deficiency
0.001 0.912 0.087
E07 Other disorders of thyroid
0.000 0.915 0.085
E04 Other non-toxic goitre
0.000 0.916 0.084
E67.8 Other specified hyperalimentation
0.000 0.916 0.084
E67.3 Hypervitaminosis D
0.000 0.916 0.084
E67.2 Megavitamin-B6 syndrome
0.000 0.916 0.084
E67.1 Hypercarotenaemia
0.000 0.916 0.084
E67.0 Hypervitaminosis A
0.000 0.916 0.084
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.920 0.080
E00 Congenital iodine-deficiency syndrome
0.000 0.920 0.080
E06 Thyroiditis
0.000 0.920 0.080
E11.3 With ophthalmic complications
0.000 0.922 0.078
E50-E64 Other nutritional deficiencies
0.000 0.922 0.078
E78.4 Other hyperlipidaemia
0.000 0.922 0.078
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.923 0.077
E89.3 Postprocedural hypopituitarism
0.000 0.924 0.076
E14.9 Without complications
0.000 0.925 0.075
E78.6 Lipoprotein deficiency
0.000 0.926 0.074
E04.9 Non-toxic goitre, unspecified
0.000 0.926 0.074
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.927 0.073
E03 Other hypothyroidism
0.000 0.927 0.073
E78.3 Hyperchylomicronaemia
0.000 0.929 0.071
E07.9 Disorder of thyroid, unspecified
0.000 0.929 0.071
E87.3 Alkalosis
0.000 0.929 0.071
E83.5 Disorders of calcium metabolism
0.000 0.930 0.070
E78.1 Pure hyperglyceridaemia
0.000 0.933 0.067
E03.8 Other specified hypothyroidism
0.000 0.934 0.066
E20-E35 Disorders of other endocrine glands
0.000 0.935 0.065
E78.2 Mixed hyperlipidaemia
0.000 0.935 0.065
E87.0 Hyperosmolality and hypernatraemia
0.000 0.936 0.064
E04.0 Non-toxic diffuse goitre
0.000 0.936 0.064
E06.3 Autoimmune thyroiditis
0.000 0.938 0.062
E07.1 Dyshormogenetic goitre
0.000 0.939 0.061
E07.0 Hypersecretion of calcitonin
0.000 0.939 0.061
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.939 0.061
E04.8 Other specified non-toxic goitre
0.000 0.939 0.061
E66 Obesity
0.000 0.941 0.059
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.942 0.057
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.942 0.057
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.942 0.057
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.942 0.057
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.942 0.057
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.942 0.057
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.942 0.057
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.942 0.057
E06.5 Other chronic thyroiditis
0.000 0.943 0.057
E06.4 Drug-induced thyroiditis
0.000 0.943 0.057
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.943 0.057
E06.1 Subacute thyroiditis
0.000 0.943 0.057
E06.0 Acute thyroiditis
0.000 0.943 0.057
E87.7 Fluid overload
0.000 0.943 0.057
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.944 0.056
E63 Other nutritional deficiencies
0.000 0.944 0.056
E56 Other vitamin deficiencies
0.000 0.944 0.056
E50 Vitamin A deficiency
0.000 0.944 0.056
E60 Dietary zinc deficiency
0.000 0.944 0.056
E59 Dietary selenium deficiency
0.000 0.944 0.056
E54 Ascorbic acid deficiency
0.000 0.944 0.056
E52 Niacin deficiency [pellagra]
0.000 0.944 0.056
E87.2 Acidosis
0.000 0.944 0.056
E87.4 Mixed disorder of acid-base balance
0.000 0.944 0.056
E58 Dietary calcium deficiency
0.000 0.944 0.055
E04.2 Non-toxic multinodular goitre
0.000 0.945 0.055
E07.8 Other specified disorders of thyroid
0.000 0.946 0.054
E03.5 Myxoedema coma
0.000 0.947 0.052
E03.4 Atrophy of thyroid (acquired)
0.000 0.947 0.052
E03.3 Postinfectious hypothyroidism
0.000 0.947 0.052
E03.1 Congenital hypothyroidism without goitre
0.000 0.947 0.052
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.947 0.052
E51 Thiamine deficiency
0.000 0.948 0.051
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.949 0.051
E53 Deficiency of other B group vitamins
0.000 0.949 0.051
E06.9 Thyroiditis, unspecified
0.000 0.950 0.050
E20 Hypoparathyroidism
0.000 0.950 0.050
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.951 0.049
E28 Ovarian dysfunction
0.000 0.951 0.049
E26 Hyperaldosteronism
0.000 0.951 0.049
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.953 0.047
E32 Diseases of thymus
0.000 0.953 0.047
E31 Polyglandular dysfunction
0.000 0.953 0.047
E30 Disorders of puberty, not elsewhere classified
0.000 0.953 0.047
E25 Adrenogenital disorders
0.000 0.953 0.047
E23 Hypofunction and other disorders of pituitary gland
0.000 0.953 0.047
E29 Testicular dysfunction
0.000 0.953 0.047
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.953 0.047
E87.5 Hyperkalaemia
0.000 0.956 0.044
E55 Vitamin D deficiency
0.000 0.957 0.043
E23.2 Diabetes insipidus
0.000 0.957 0.043
E04.1 Non-toxic single thyroid nodule
0.000 0.957 0.043
E34 Other endocrine disorders
0.000 0.957 0.043
E28.2 Polycystic ovarian syndrome
0.000 0.957 0.043
E24 Cushing's syndrome
0.000 0.957 0.043
E66.1 Drug-induced obesity
0.000 0.958 0.042
E78.8 Other disorders of lipoprotein metabolism
0.000 0.958 0.042
E73.9 Lactose intolerance, unspecified
0.001 0.959 0.040
R31 Unspecified haematuria
0.041 0.959 0.000
E66.0 Obesity due to excess calories
0.000 0.959 0.041
E50.9 Vitamin A deficiency, unspecified
0.000 0.959 0.040
E50.8 Other manifestations of vitamin A deficiency
0.000 0.959 0.040
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.959 0.040
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.959 0.040
E50.5 Vitamin A deficiency with night blindness
0.000 0.959 0.040
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.959 0.040
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.959 0.040
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.959 0.040
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.959 0.040
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.959 0.040
E56.9 Vitamin deficiency, unspecified
0.000 0.959 0.040
E56.8 Deficiency of other vitamins
0.000 0.959 0.040
E56.1 Deficiency of vitamin K
0.000 0.959 0.040
E56.0 Deficiency of vitamin E
0.000 0.959 0.040
E63.9 Nutritional deficiency, unspecified
0.000 0.959 0.040
E63.8 Other specified nutritional deficiencies
0.000 0.959 0.040
E63.1 Imbalance of constituents of food intake
0.000 0.959 0.040
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.959 0.040
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.959 0.040
E64.8 Sequelae of other nutritional deficiencies
0.000 0.959 0.040
E64.3 Sequelae of rickets
0.000 0.959 0.040
E64.2 Sequelae of vitamin C deficiency
0.000 0.959 0.040
E64.1 Sequelae of vitamin A deficiency
0.000 0.959 0.040
E64.0 Sequelae of protein-energy malnutrition
0.000 0.959 0.040
E27 Other disorders of adrenal gland
0.000 0.960 0.040
E20.9 Hypoparathyroidism, unspecified
0.000 0.961 0.039
E51.9 Thiamine deficiency, unspecified
0.000 0.963 0.037
E51.8 Other manifestations of thiamine deficiency
0.000 0.963 0.037
E51.1 Beriberi
0.000 0.963 0.037
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.963 0.037
E27.1 Primary adrenocortical insufficiency
0.000 0.963 0.037
E53.1 Pyridoxine deficiency
0.000 0.963 0.037
E53.0 Riboflavin deficiency
0.000 0.963 0.037
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.963 0.037
E53.9 Vitamin B deficiency, unspecified
0.000 0.963 0.037
E26.0 Primary hyperaldosteronism
0.000 0.963 0.036
E20.8 Other hypoparathyroidism
0.000 0.964 0.036
E20.1 Pseudohypoparathyroidism
0.000 0.964 0.036
E20.0 Idiopathic hypoparathyroidism
0.000 0.964 0.036
E24.2 Drug-induced Cushing's syndrome
0.000 0.964 0.036
E28.9 Ovarian dysfunction, unspecified
0.000 0.965 0.035
E28.8 Other ovarian dysfunction
0.000 0.965 0.035
E28.1 Androgen excess
0.000 0.965 0.035
E28.0 Oestrogen excess
0.000 0.965 0.035
E26.9 Hyperaldosteronism, unspecified
0.000 0.965 0.035
E26.8 Other hyperaldosteronism
0.000 0.965 0.035
E26.1 Secondary hyperaldosteronism
0.000 0.965 0.035
E05.8 Other thyrotoxicosis
0.000 0.965 0.035
E25.9 Adrenogenital disorder, unspecified
0.000 0.966 0.034
E25.8 Other adrenogenital disorders
0.000 0.966 0.034
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.966 0.034
E30.9 Disorder of puberty, unspecified
0.000 0.966 0.034
E30.8 Other disorders of puberty
0.000 0.966 0.034
E30.1 Precocious puberty
0.000 0.966 0.034
E30.0 Delayed puberty
0.000 0.966 0.034
E31.9 Polyglandular dysfunction, unspecified
0.000 0.966 0.034
E31.8 Other polyglandular dysfunction
0.000 0.966 0.034
E31.1 Polyglandular hyperfunction
0.000 0.966 0.034
E31.0 Autoimmune polyglandular failure
0.000 0.966 0.034
E32.9 Disease of thymus, unspecified
0.000 0.966 0.034
E32.8 Other diseases of thymus
0.000 0.966 0.034
E32.1 Abscess of thymus
0.000 0.966 0.034
E32.0 Persistent hyperplasia of thymus
0.000 0.966 0.034
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.966 0.034
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.966 0.034
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.966 0.034
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.966 0.034
E23.1 Drug-induced hypopituitarism
0.000 0.966 0.034
E29.9 Testicular dysfunction, unspecified
0.000 0.966 0.034
E29.8 Other testicular dysfunction
0.000 0.966 0.034
E29.0 Testicular hyperfunction
0.000 0.966 0.034
E05.5 Thyroid crisis or storm
0.000 0.966 0.034
E05.4 Thyrotoxicosis factitia
0.000 0.966 0.034
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.966 0.034
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.966 0.034
E29.1 Testicular hypofunction
0.000 0.967 0.033
E23.7 Disorder of pituitary gland, unspecified
0.000 0.967 0.033
E51.2 Wernicke's encephalopathy
0.000 0.967 0.033
E53.8 Deficiency of other specified B group vitamins
0.000 0.968 0.032
E55.0 Rickets, active
0.000 0.969 0.031
E34.5 Androgen resistance syndrome
0.000 0.969 0.031
E34.4 Constitutional tall stature
0.000 0.969 0.031
E34.3 Short stature, not elsewhere classified
0.000 0.969 0.031
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.969 0.031
E34.1 Other hypersecretion of intestinal hormones
0.000 0.969 0.031
E24.8 Other Cushing's syndrome
0.000 0.969 0.031
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.969 0.031
E24.3 Ectopic ACTH syndrome
0.000 0.969 0.031
E24.1 Nelson's syndrome
0.000 0.969 0.031
E34.9 Endocrine disorder, unspecified
0.000 0.969 0.031
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.969 0.030
E34.8 Other specified endocrine disorders
0.000 0.970 0.030
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.970 0.030
E23.6 Other disorders of pituitary gland
0.000 0.970 0.030
E61 Deficiency of other nutrient elements
0.001 0.970 0.029
E27.5 Adrenomedullary hyperfunction
0.000 0.971 0.029
E27.0 Other adrenocortical overactivity
0.000 0.971 0.029
E34.0 Carcinoid syndrome
0.000 0.972 0.028
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.972 0.028
E24.0 Pituitary-dependent Cushing's disease
0.000 0.972 0.027
E28.3 Primary ovarian failure
0.000 0.977 0.022
E21.3 Hyperparathyroidism, unspecified
0.000 0.977 0.023
E27.2 Addisonian crisis
0.000 0.978 0.022
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.978 0.022
E86 Volume depletion
0.000 0.978 0.022
E21.4 Other specified disorders of parathyroid gland
0.000 0.978 0.022
E21.2 Other hyperparathyroidism
0.000 0.978 0.022
E24.9 Cushing's syndrome, unspecified
0.000 0.978 0.022
E61.9 Deficiency of nutrient element, unspecified
0.001 0.978 0.021
E61.8 Deficiency of other specified nutrient elements
0.001 0.978 0.021
E61.7 Deficiency of multiple nutrient elements
0.001 0.978 0.021
E61.6 Vanadium deficiency
0.001 0.978 0.021
E61.5 Molybdenum deficiency
0.001 0.978 0.021
E61.4 Chromium deficiency
0.001 0.978 0.021
E61.3 Manganese deficiency
0.001 0.978 0.021
E61.0 Copper deficiency
0.001 0.978 0.021
E22 Hyperfunction of pituitary gland
0.000 0.979 0.021
E66.9 Obesity, unspecified
0.000 0.979 0.021
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.980 0.020
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.980 0.020
E27.8 Other specified disorders of adrenal gland
0.000 0.981 0.019
E55.9 Vitamin D deficiency, unspecified
0.000 0.981 0.018
K90-K93 Other diseases of the digestive system
0.000 0.982 0.018
E23.0 Hypopituitarism
0.000 0.982 0.017
E27.9 Disorder of adrenal gland, unspecified
0.000 0.983 0.017
E61.2 Magnesium deficiency
0.001 0.983 0.016
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.985 0.015
E22.8 Other hyperfunction of pituitary gland
0.000 0.985 0.015
E22.1 Hyperprolactinaemia
0.000 0.986 0.014
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.987 0.013
C71.2 Temporal lobe
0.013 0.987 0.000
C71 Malignant neoplasm of brain
0.013 0.987 0.000
C71.9 Brain, unspecified
0.013 0.987 0.000
E21.0 Primary hyperparathyroidism
0.000 0.988 0.012
C71.3 Parietal lobe
0.011 0.989 0.000
C71.1 Frontal lobe
0.011 0.989 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.989 0.011
E22.0 Acromegaly and pituitary gigantism
0.000 0.990 0.010
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.990 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.990 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.990 0.010
E87.6 Hypokalaemia
0.000 0.990 0.010
C71.7 Brain stem
0.010 0.990 0.000
C71.6 Cerebellum
0.009 0.991 0.000
C71.5 Cerebral ventricle
0.009 0.991 0.000
C71.0 Cerebrum, except lobes and ventricles
0.009 0.991 0.000
C71.8 Overlapping lesion of brain
0.009 0.991 0.000
G44.2 Tension-type headache
0.009 0.991 0.000
M41.9 Scoliosis, unspecified
0.009 0.991 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.009 0.991 0.000
G31.8 Other specified degenerative diseases of nervous system
0.000 0.991 0.009
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.009 0.991 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.008 0.992 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.008 0.992 0.000
E66.8 Other obesity
0.000 0.992 0.008
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.992 0.008
C71.4 Occipital lobe
0.008 0.992 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.992 0.008
E61.1 Iron deficiency
0.001 0.992 0.006
G31.0 Circumscribed brain atrophy
0.000 0.992 0.008
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.007 0.993 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.993 0.007
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.007 0.993 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.007 0.993 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.007 0.993 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.007 0.993 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.007 0.993 0.000
C69 Malignant neoplasm of eye and adnexa
0.006 0.993 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.994 0.006
C70 Malignant neoplasm of meninges
0.006 0.994 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.006 0.994 0.000
N04.9 Unspecified
0.000 0.994 0.006
G54.9 Nerve root and plexus disorder, unspecified
0.006 0.994 0.000
C69.9 Eye, unspecified
0.006 0.994 0.000
M79.10 Myalgia (Multiple sites)
0.006 0.994 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.005 0.995 0.000
C69.3 Choroid
0.005 0.995 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.995 0.005
G31.2 Degeneration of nervous system due to alcohol
0.000 0.995 0.005
C69.8 Overlapping lesion of eye and adnexa
0.005 0.995 0.000
C69.5 Lachrymal gland and duct
0.005 0.995 0.000
C69.4 Ciliary body
0.005 0.995 0.000
C69.2 Retina
0.005 0.995 0.000
C69.1 Cornea
0.005 0.995 0.000
C70.0 Cerebral meninges
0.005 0.995 0.000
C69.6 Orbit
0.005 0.995 0.000
C69.0 Conjunctiva
0.005 0.995 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.995 0.005
C70.9 Meninges, unspecified
0.004 0.995 0.000
C70.1 Spinal meninges
0.004 0.995 0.000
G44 Other headache syndromes
0.005 0.995 0.000
G30 Alzheimer's disease
0.000 0.996 0.004
M41 Scoliosis
0.004 0.996 0.000
K62.5 Haemorrhage of anus and rectum
0.004 0.996 0.000
I31.9 Disease of pericardium, unspecified
0.000 0.996 0.004
C72.9 Central nervous system, unspecified
0.004 0.996 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.004 0.996 0.000
C72.5 Other and unspecified cranial nerves
0.004 0.996 0.000
C72.4 Acoustic nerve
0.004 0.996 0.000
C72.3 Optic nerve
0.004 0.996 0.000
C72.2 Olfactory nerve
0.004 0.996 0.000
C72.1 Cauda equina
0.004 0.996 0.000
G44.8 Other specified headache syndromes
0.004 0.996 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.996 0.004
M22.2 Patellofemoral disorders
0.004 0.996 0.000
C72.0 Spinal cord
0.004 0.996 0.000
R52.1 Chronic intractable pain
0.004 0.996 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.004 0.996 0.000
M79.19 Myalgia (Site unspecified)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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