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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs450630
log Bayes Factor = 47.714
Chromosome 6   position 28,542,424  (GRCh37) Explore rs450630 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E83 Disorders of mineral metabolism
0.000 0.485 0.515
E83.3 Disorders of phosphorus metabolism
0.000 0.512 0.488
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.631 0.369
E83.8 Other disorders of mineral metabolism
0.000 0.631 0.369
E83.2 Disorders of zinc metabolism
0.000 0.631 0.369
E83.0 Disorders of copper metabolism
0.000 0.631 0.369
E83.4 Disorders of magnesium metabolism
0.000 0.659 0.341
K90 Intestinal malabsorption
0.332 0.668 0.000
K90.8 Other intestinal malabsorption
0.243 0.757 0.000
K90.3 Pancreatic steatorrhoea
0.238 0.762 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.238 0.762 0.000
K90.1 Tropical sprue
0.238 0.762 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.238 0.762 0.000
K90.9 Intestinal malabsorption, unspecified
0.180 0.820 0.000
E10.9 Without complications
0.082 0.918 0.000
E10 Insulin-dependent diabetes mellitus
0.077 0.923 0.000
E10.3 With ophthalmic complications
0.073 0.927 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.928 0.072
E10.4 With neurological complications
0.070 0.930 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.068 0.932 0.000
E10.6 With other specified complications
0.066 0.933 0.000
E10.2 With renal complications
0.063 0.937 0.000
S02.4 Fracture of malar and maxillary bones
0.059 0.941 0.000
S02 Fracture of skull and facial bones
0.055 0.945 0.000
E10.7 With multiple complications
0.054 0.946 0.000
E10.1 With ketoacidosis
0.053 0.947 0.000
S02.8 Fractures of other skull and facial bones
0.053 0.947 0.000
E10.0 With coma
0.053 0.947 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.053 0.947 0.000
E10.5 With peripheral circulatory complications
0.050 0.950 0.000
S02.2 Fracture of nasal bones
0.047 0.953 0.000
S02.5 Fracture of tooth
0.047 0.953 0.000
E83.5 Disorders of calcium metabolism
0.000 0.954 0.046
S02.3 Fracture of orbital floor
0.046 0.954 0.000
E10.8 With unspecified complications
0.044 0.956 0.000
S02.20 Fracture of nasal bones (closed)
0.041 0.959 0.000
S02.50 Fracture of tooth (closed)
0.041 0.959 0.000
E05.9 Thyrotoxicosis, unspecified
0.041 0.959 0.000
S02.7 Multiple fractures involving skull and facial bones
0.040 0.960 0.000
S02.0 Fracture of vault of skull
0.040 0.960 0.000
S02.30 Fracture of orbital floor (closed)
0.039 0.961 0.000
S02.81 Fractures of other skull and facial bones (open)
0.038 0.962 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.038 0.962 0.000
N50.8 Other specified disorders of male genital organs
0.035 0.965 0.000
S02.21 Fracture of nasal bones (open)
0.034 0.966 0.000
S02.51 Fracture of tooth (open)
0.034 0.966 0.000
E80.4 Gilbert's syndrome
0.000 0.967 0.033
S02.31 Fracture of orbital floor (open)
0.033 0.967 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.033 0.967 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.968 0.032
S02.1 Fracture of base of skull
0.031 0.969 0.000
E70-E90 Metabolic disorders
0.000 0.969 0.031
S02.70 Multiple fractures involving skull and facial bones (closed)
0.030 0.970 0.000
S02.6 Fracture of mandible
0.029 0.970 0.000
S02.00 Fracture of vault of skull (closed)
0.029 0.970 0.000
S02.71 Multiple fractures involving skull and facial bones (open)
0.029 0.971 0.000
S02.01 Fracture of vault of skull (open)
0.029 0.971 0.000
E80.1 Porphyria cutanea tarda
0.000 0.972 0.028
D50.8 Other iron deficiency anaemias
0.027 0.973 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.975 0.025
E85 Amyloidosis
0.000 0.975 0.025
E80.2 Other porphyria
0.000 0.975 0.024
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.024 0.976 0.000
E10-E14 Diabetes mellitus
0.024 0.976 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.976 0.023
E80.5 Crigler-Najjar syndrome
0.000 0.976 0.023
E80.3 Defects of catalase and peroxydase
0.000 0.976 0.023
E80.0 Hereditary erythropoietic porphyria
0.000 0.976 0.023
E80.6 Other disorders of bilirubin metabolism
0.000 0.977 0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.977 0.023
E77 Disorders of glycoprotein metabolism
0.000 0.978 0.022
E76 Disorders of glycosaminoglycan metabolism
0.000 0.978 0.022
E72 Other disorders of amino-acid metabolism
0.000 0.978 0.022
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.978 0.022
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.978 0.022
S02.11 Fracture of base of skull (open)
0.022 0.978 0.000
E85.9 Amyloidosis, unspecified
0.000 0.978 0.022
E74 Other disorders of carbohydrate metabolism
0.000 0.979 0.021
S02.61 Fracture of mandible (open)
0.021 0.979 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.979 0.021
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.979 0.021
E05 Thyrotoxicosis [hyperthyroidism]
0.020 0.980 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.980 0.020
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.020 0.980 0.000
E16.2 Hypoglycaemia, unspecified
0.020 0.980 0.000
O04.9 Complete or unspecified, without complication
0.000 0.980 0.020
E73 Lactose intolerance
0.000 0.981 0.019
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.981 0.019
E13 Other specified diabetes mellitus
0.019 0.981 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.982 0.018
E70.3 Albinism
0.000 0.982 0.018
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.982 0.018
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.982 0.018
E79.1 Lesch-Nyhan syndrome
0.000 0.982 0.018
E85.8 Other amyloidosis
0.000 0.982 0.018
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.982 0.018
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.982 0.018
R31 Unspecified haematuria
0.000 0.982 0.018
E89.2 Postprocedural hypoparathyroidism
0.000 0.982 0.018
E84 Cystic fibrosis
0.000 0.982 0.017
E89.1 Postprocedural hypoinsulinaemia
0.000 0.983 0.017
E12 Malnutrition-related diabetes mellitus
0.017 0.983 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.017 0.983 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.983 0.017
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.983 0.017
E70.2 Disorders of tyrosine metabolism
0.000 0.983 0.017
E70.1 Other hyperphenylalaninaemias
0.000 0.983 0.017
E70.0 Classical phenylketonuria
0.000 0.983 0.017
E05.0 Thyrotoxicosis with diffuse goitre
0.017 0.983 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.983 0.017
E89.5 Postprocedural testicular hypofunction
0.000 0.983 0.017
E71.3 Disorders of fatty-acid metabolism
0.000 0.984 0.016
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.984 0.016
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.984 0.016
E71.0 Maple-syrup-urine disease
0.000 0.984 0.016
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.984 0.016
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.984 0.016
E72.5 Disorders of glycine metabolism
0.000 0.984 0.016
E72.4 Disorders of ornithine metabolism
0.000 0.984 0.016
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.984 0.016
E72.2 Disorders of urea cycle metabolism
0.000 0.984 0.016
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.984 0.016
E72.0 Disorders of amino-acid transport
0.000 0.984 0.016
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.984 0.016
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.984 0.016
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.984 0.016
E76.2 Other mucopolysaccharidoses
0.000 0.984 0.016
E76.1 Mucopolysaccharidosis, type II
0.000 0.984 0.016
E76.0 Mucopolysaccharidosis, type I
0.000 0.984 0.016
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.984 0.016
E77.8 Other disorders of glycoprotein metabolism
0.000 0.984 0.016
E77.1 Defects in glycoprotein degradation
0.000 0.984 0.016
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.984 0.016
E14 Unspecified diabetes mellitus
0.016 0.984 0.000
O04 Medical abortion
0.000 0.984 0.016
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.984 0.016
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.984 0.016
E05.8 Other thyrotoxicosis
0.016 0.984 0.000
S02.10 Fracture of base of skull (closed)
0.016 0.984 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.984 0.015
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.984 0.015
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.984 0.015
E74.2 Disorders of galactose metabolism
0.000 0.984 0.015
E74.1 Disorders of fructose metabolism
0.000 0.984 0.015
E74.0 Glycogen storage disease
0.000 0.984 0.015
E89.4 Postprocedural ovarian failure
0.000 0.984 0.015
E16 Other disorders of pancreatic internal secretion
0.015 0.985 0.000
E13.9 Without complications
0.015 0.985 0.000
E05.5 Thyroid crisis or storm
0.015 0.985 0.000
E05.4 Thyrotoxicosis factitia
0.015 0.985 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.015 0.985 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.015 0.985 0.000
E85.4 Organ-limited amyloidosis
0.000 0.985 0.015
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.985 0.014
K93 Disorders of other digestive organs in diseases classified elsewhere
0.014 0.986 0.000
E73.8 Other lactose intolerance
0.000 0.986 0.014
E73.1 Secondary lactase deficiency
0.000 0.986 0.014
E73.0 Congenital lactase deficiency
0.000 0.986 0.014
E75.6 Lipid storage disorder, unspecified
0.000 0.986 0.014
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.986 0.014
E75.3 Sphingolipidosis, unspecified
0.000 0.986 0.014
E75.1 Other gangliosidosis
0.000 0.986 0.014
E75.0 GM2 gangliosidosis
0.000 0.986 0.014
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.986 0.014
E13.8 With unspecified complications
0.013 0.986 0.000
E13.7 With multiple complications
0.013 0.986 0.000
E13.6 With other specified complications
0.013 0.986 0.000
E13.5 With peripheral circulatory complications
0.013 0.986 0.000
E13.4 With neurological complications
0.013 0.986 0.000
E13.2 With renal complications
0.013 0.986 0.000
E13.1 With ketoacidosis
0.013 0.986 0.000
E13.0 With coma
0.013 0.986 0.000
E75.2 Other sphingolipidosis
0.000 0.987 0.013
E13.3 With ophthalmic complications
0.013 0.987 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.000 0.987 0.013
E14.4 With neurological complications
0.013 0.987 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.013 0.987 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.987 0.012
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.987 0.012
E12.9 Without complications
0.012 0.987 0.000
E12.8 With unspecified complications
0.012 0.987 0.000
E12.7 With multiple complications
0.012 0.987 0.000
E12.6 With other specified complications
0.012 0.987 0.000
E12.5 With peripheral circulatory complications
0.012 0.987 0.000
E12.4 With neurological complications
0.012 0.987 0.000
E12.3 With ophthalmic complications
0.012 0.987 0.000
E12.2 With renal complications
0.012 0.987 0.000
E12.1 With ketoacidosis
0.012 0.987 0.000
E12.0 With coma
0.012 0.987 0.000
E14.3 With ophthalmic complications
0.012 0.988 0.000
I83 Varicose veins of lower extremities
0.000 0.988 0.012
M13.00 Polyarthritis, unspecified (Multiple sites)
0.012 0.988 0.000
E14.9 Without complications
0.012 0.988 0.000
E14.6 With other specified complications
0.012 0.988 0.000
E14.7 With multiple complications
0.012 0.988 0.000
E14.0 With coma
0.012 0.988 0.000
O04.7 Complete or unspecified, complicated by embolism
0.000 0.988 0.012
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.988 0.012
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.988 0.012
O04.3 Incomplete, with other and unspecified complications
0.000 0.988 0.012
O04.2 Incomplete, complicated by embolism
0.000 0.988 0.012
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.988 0.012
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.988 0.012
E14.5 With peripheral circulatory complications
0.012 0.988 0.000
E14.2 Withrenal complications
0.012 0.988 0.000
S02.60 Fracture of mandible (closed)
0.011 0.989 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.011 0.989 0.000
E75.5 Other lipid storage disorders
0.000 0.989 0.011
Chapter IV Endocrine, nutritional and metabolic diseases
0.011 0.989 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.011 0.989 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.011 0.989 0.000
E16.4 Abnormal secretion of gastrin
0.011 0.989 0.000
E16.3 Increased secretion of glucagon
0.011 0.989 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.011 0.989 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.989 0.011
S00-S09 Injuries to the head
0.011 0.989 0.000
E14.1 With ketoacidosis
0.011 0.989 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.010 0.989 0.000
K93.1 Megacolon in Chagas' disease
0.010 0.989 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.010 0.989 0.000
S92.30 Fracture of metatarsal bone (closed)
0.011 0.989 0.000
E00-E07 Disorders of thyroid gland
0.010 0.990 0.000
E14.8 With unspecified complications
0.010 0.990 0.000
M13.0 Polyarthritis, unspecified
0.010 0.990 0.000
M07.3 Other psoriatic arthropathies
0.010 0.990 0.000
E40-E46 Malnutrition
0.010 0.990 0.000
S06 Intracranial injury
0.010 0.990 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.990 0.010
E16.1 Other hypoglycaemia
0.010 0.990 0.000
E15 Nondiabetic hypoglycaemic coma
0.009 0.990 0.000
E84.9 Cystic fibrosis, unspecified
0.001 0.990 0.009
M07.39 Other psoriatic arthropathies (Site unspecified)
0.009 0.991 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.009 0.991 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.009 0.991 0.000
E46 Unspecified protein-energy malnutrition
0.009 0.991 0.000
S06.5 Traumatic subdural haemorrhage
0.009 0.991 0.000
S99.9 Unspecified injury of ankle and foot
0.009 0.991 0.000
S92.3 Fracture of metatarsal bone
0.009 0.991 0.000
M07.38 Other psoriatic arthropathies (Other)
0.009 0.991 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.009 0.991 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.009 0.991 0.000
E88 Other metabolic disorders
0.000 0.992 0.008
S06.2 Diffuse brain injury
0.008 0.992 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.008 0.992 0.000
M13.06 Polyarthritis, unspecified (Lower leg)
0.008 0.992 0.000
S08 Traumatic amputation of part of head
0.008 0.992 0.000
S07 Crushing injury of head
0.008 0.992 0.000
S04 Injury of cranial nerves
0.008 0.992 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.008 0.992 0.000
S00 Superficial injury of head
0.008 0.992 0.000
O04.4 Incomplete, without complication
0.000 0.992 0.008
M07.31 Other psoriatic arthropathies (Shoulder region)
0.008 0.992 0.000
S99 Other and unspecified injuries of ankle and foot
0.008 0.992 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.000 0.992 0.008
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.008 0.992 0.000
E00 Congenital iodine-deficiency syndrome
0.008 0.992 0.000
S92 Fracture of foot, except ankle
0.008 0.992 0.000
S06.0 Concussion
0.008 0.992 0.000
M13.08 Polyarthritis, unspecified (Other)
0.007 0.992 0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.007 0.992 0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.007 0.992 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.007 0.992 0.000
M13.03 Polyarthritis, unspecified (Forearm)
0.007 0.992 0.000
M13.02 Polyarthritis, unspecified (Upper arm)
0.007 0.992 0.000
M13.01 Polyarthritis, unspecified (Shoulder region)
0.007 0.992 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.007 0.992 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.007 0.992 0.000
S06.1 Traumatic cerebral oedema
0.007 0.992 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.007 0.993 0.000
E45 Retarded development following protein-energy malnutrition
0.007 0.993 0.000
E43 Unspecified severe protein-energy malnutrition
0.007 0.993 0.000
E42 Marasmic kwashiorkor
0.007 0.993 0.000
E41 Nutritional marasmus
0.007 0.993 0.000
E40 Kwashiorkor
0.007 0.993 0.000
S06.7 Intracranial injury with prolonged coma
0.007 0.993 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.007 0.993 0.000
S00.0 Superficial injury of scalp
0.007 0.993 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.007 0.993 0.000
S06.9 Intracranial injury, unspecified
0.007 0.993 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.007 0.993 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.007 0.993 0.000
S90.8 Other superficial injuries of ankle and foot
0.007 0.993 0.000
E06 Thyroiditis
0.007 0.993 0.000
S05 Injury of eye and orbit
0.007 0.993 0.000
O00-O08 Pregnancy with abortive outcome
0.000 0.993 0.007
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.007 0.993 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.007 0.993 0.000
S90 Superficial injury of ankle and foot
0.007 0.993 0.000
M07 Psoriatic and enteropathic arthropathies
0.007 0.993 0.000
S90-S99 Injuries to the ankle and foot
0.007 0.993 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.993 0.007
S00.4 Superficial injury of ear
0.007 0.993 0.000
S06.8 Other intracranial injuries
0.007 0.993 0.000
D50 Iron deficiency anaemia
0.007 0.993 0.000
S92.31 Fracture of metatarsal bone (open)
0.006 0.993 0.000
E88.8 Other specified metabolic disorders
0.000 0.993 0.006
S30.1 Contusion of abdominal wall
0.000 0.993 0.007
S06.3 Focal brain injury
0.006 0.993 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.000 0.993 0.006
S03.1 Dislocation of septal cartilage of nose
0.006 0.993 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.006 0.994 0.000
E50-E64 Other nutritional deficiencies
0.006 0.994 0.000
S92.9 Fracture of foot, unspecified
0.006 0.994 0.000
N50 Other disorders of male genital organs
0.006 0.994 0.000
S06.4 Epidural haemorrhage
0.006 0.994 0.000
E07 Other disorders of thyroid
0.006 0.994 0.000
S06.21 Diffuse brain injury (with open intracranial wound)
0.006 0.994 0.000
S00.7 Multiple superficial injuries of head
0.006 0.994 0.000
S99.8 Other specified injuries of ankle and foot
0.006 0.994 0.000
I42.9 Cardiomyopathy, unspecified
0.000 0.994 0.006
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.006 0.994 0.000
S05.1 Contusion of eyeball and orbital tissues
0.006 0.994 0.000
S08.1 Traumatic amputation of ear
0.006 0.994 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.005 0.994 0.001
S08.9 Traumatic amputation of unspecified part of head
0.006 0.994 0.000
S08.8 Traumatic amputation of other parts of head
0.006 0.994 0.000
S08.0 Avulsion of scalp
0.006 0.994 0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.006 0.994 0.000
S03.4 Sprain and strain of jaw
0.006 0.994 0.000
S03.3 Dislocation of other and unspecified parts of head
0.006 0.994 0.000
S03.0 Dislocation of jaw
0.006 0.994 0.000
S04.9 Injury of unspecified cranial nerve
0.006 0.994 0.000
S04.8 Injury of other cranial nerves
0.006 0.994 0.000
S04.7 Injury of accessory nerve
0.006 0.994 0.000
S04.6 Injury of acoustic nerve
0.006 0.994 0.000
S04.5 Injury of facial nerve
0.006 0.994 0.000
S04.4 Injury of abducent nerve
0.006 0.994 0.000
S04.3 Injury of trigeminal nerve
0.006 0.994 0.000
S04.2 Injury of trochlear nerve
0.006 0.994 0.000
S04.1 Injury of oculomotor nerve
0.006 0.994 0.000
S04.0 Injury of optic nerve and pathways
0.006 0.994 0.000
S07.9 Crushing injury of head, part unspecified
0.006 0.994 0.000
S07.8 Crushing injury of other parts of head
0.006 0.994 0.000
S07.1 Crushing injury of skull
0.006 0.994 0.000
S07.0 Crushing injury of face
0.006 0.994 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.994 0.006
S00.5 Superficial injury of lip and oral cavity
0.006 0.994 0.000
O02 Other abnormal products of conception
0.000 0.994 0.006
S90.9 Superficial injury of ankle and foot, unspecified
0.006 0.994 0.000
S99.7 Multiple injuries of ankle and foot
0.006 0.994 0.000
S92.0 Fracture of calcaneus
0.006 0.994 0.000
S06.00 Concussion (without open intracranial wound)
0.006 0.994 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.006 0.994 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.006 0.994 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.006 0.994 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.006 0.994 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.006 0.994 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.006 0.994 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.006 0.994 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.006 0.994 0.000
S92.4 Fracture of great toe
0.006 0.994 0.000
E88.3 Tumour lysis syndrome
0.000 0.994 0.005
S06.01 Concussion (with open intracranial wound)
0.006 0.994 0.000
E06.5 Other chronic thyroiditis
0.006 0.994 0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.005 0.994 0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.005 0.994 0.000
S00.1 Contusion of eyelid and periocular area
0.006 0.994 0.000
E06.9 Thyroiditis, unspecified
0.006 0.994 0.000
E44.1 Mild protein-energy malnutrition
0.005 0.994 0.000
E44.0 Moderate protein-energy malnutrition
0.005 0.994 0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.005 0.994 0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.005 0.994 0.000
M45 Ankylosing spondylitis
0.000 0.994 0.006
O03 Spontaneous abortion
0.000 0.994 0.006
S92.1 Fracture of talus
0.005 0.994 0.000
S09 Other and unspecified injuries of head
0.006 0.994 0.000
S92.7 Multiple fractures of foot
0.005 0.994 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.005 0.994 0.000
S92.2 Fracture of other tarsal bone(s)
0.005 0.995 0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.005 0.995 0.000
S92.5 Fracture of other toe
0.005 0.995 0.000
S03.2 Dislocation of tooth
0.005 0.995 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.000 0.995 0.005
S92.90 Fracture of foot, unspecified (closed)
0.005 0.995 0.000
L43.9 Lichen planus, unspecified
0.005 0.995 0.000
M07.6 Other enteropathic arthropathies
0.005 0.995 0.000
E06.4 Drug-induced thyroiditis
0.005 0.995 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.005 0.995 0.000
E06.0 Acute thyroiditis
0.005 0.995 0.000
E07.8 Other specified disorders of thyroid
0.005 0.995 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.005 0.995 0.000
S05.7 Avulsion of eye
0.005 0.995 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.005 0.995 0.000
O07 Failed attempted abortion
0.000 0.995 0.005
O05 Other abortion
0.000 0.995 0.005
O01 Hydatidiform mole
0.000 0.995 0.005
S00.3 Superficial injury of nose
0.005 0.995 0.000
S90.1 Contusion of toe(s) without damage to nail
0.005 0.995 0.000
E54 Ascorbic acid deficiency
0.005 0.995 0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.005 0.995 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.005 0.995 0.000
S90.2 Contusion of toe(s) with damage to nail
0.005 0.995 0.000
M07.5 Arthropathy in ulcerative colitis
0.005 0.995 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.005 0.995 0.000
M07.2 Psoriatic spondylitis
0.005 0.995 0.000
M07.1 Arthritis mutilans
0.005 0.995 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.005 0.995 0.000
S98 Traumatic amputation of ankle and foot
0.005 0.995 0.000
S95 Injury of blood vessels at ankle and foot level
0.005 0.995 0.000
S94 Injury of nerves at ankle and foot level
0.005 0.995 0.000
S06.81 Other intracranial injuries (with open intracranial wound)
0.005 0.995 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.005 0.995 0.000
E06.1 Subacute thyroiditis
0.005 0.995 0.000
S90.0 Contusion of ankle
0.005 0.995 0.000
O03.9 Complete or unspecified, without complication
0.000 0.995 0.005
S06.31 Focal brain injury (with open intracranial wound)
0.005 0.995 0.000
D50.1 Sideropenic dysphagia
0.005 0.995 0.000
S97 Crushing injury of ankle and foot
0.005 0.995 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.005 0.995 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.005 0.995 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.000 0.995 0.005
M13 Other arthritis
0.005 0.995 0.000
E56 Other vitamin deficiencies
0.005 0.995 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.005 0.995 0.000
E63 Other nutritional deficiencies
0.005 0.995 0.000
E50 Vitamin A deficiency
0.005 0.995 0.000
E60 Dietary zinc deficiency
0.005 0.995 0.000
E59 Dietary selenium deficiency
0.005 0.995 0.000
E52 Niacin deficiency [pellagra]
0.005 0.995 0.000
S92.91 Fracture of foot, unspecified (open)
0.005 0.995 0.000
S06.41 Epidural haemorrhage (with open intracranial wound)
0.005 0.995 0.000
E88.2 Lipomatosis, not elsewhere classified
0.001 0.995 0.004
X68.9 Unspecified place
0.000 0.995 0.005
E07.1 Dyshormogenetic goitre
0.005 0.995 0.000
E07.0 Hypersecretion of calcitonin
0.005 0.995 0.000
S09.8 Other specified injuries of head
0.005 0.995 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.005 0.995 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.005 0.995 0.000
E53 Deficiency of other B group vitamins
0.005 0.995 0.000
E61 Deficiency of other nutrient elements
0.005 0.995 0.000
E51 Thiamine deficiency
0.005 0.995 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.004 0.995 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.995 0.005
O06 Unspecified abortion
0.000 0.995 0.004
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.995 0.005
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.995 0.005
O02.9 Abnormal product of conception, unspecified
0.000 0.995 0.004
O02.8 Other specified abnormal products of conception
0.000 0.995 0.004
S92.40 Fracture of great toe (closed)
0.004 0.995 0.000
S92.00 Fracture of calcaneus (closed)
0.004 0.995 0.000
S05.8 Other injuries of eye and orbit
0.004 0.995 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.004 0.995 0.000
S92.01 Fracture of calcaneus (open)
0.004 0.996 0.000
E88.9 Metabolic disorder, unspecified
0.001 0.996 0.004
S92.50 Fracture of other toe (closed)
0.004 0.996 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.000 0.996 0.004
S06.80 Other intracranial injuries (without open intracranial wound)
0.004 0.996 0.000
S92.41 Fracture of great toe (open)
0.004 0.996 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.996 0.004
S05.9 Injury of eye and orbit, part unspecified
0.004 0.996 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.004 0.996 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.996 0.004
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.996 0.004
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.996 0.004
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.996 0.004
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.996 0.004
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.996 0.004
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.000 0.996 0.004
S92.11 Fracture of talus (open)
0.004 0.996 0.000
O03.7 Complete or unspecified, complicated by embolism
0.000 0.996 0.004
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.996 0.004
O03.2 Incomplete, complicated by embolism
0.000 0.996 0.004
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.996 0.004
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
S09.7 Multiple injuries of head
0.004 0.996 0.000
S09.1 Injury of muscle and tendon of head
0.004 0.996 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.004 0.996 0.000
S92.71 Multiple fractures of foot (open)
0.004 0.996 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.996 0.004
S90.3 Contusion of other and unspecified parts of foot
0.004 0.996 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.996 0.004
S92.21 Fracture of other tarsal bone(s) (open)
0.004 0.996 0.000
L40.5 Arthropathic psoriasis
0.004 0.996 0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified
0.000 0.996 0.004
O08.8 Other complications following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.7 Other venous complications following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.4 Renal failure following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.3 Shock following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.2 Embolism following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy
0.000 0.996 0.004
E58 Dietary calcium deficiency
0.004 0.996 0.000
M07.68 Other enteropathic arthropathies (Other)
0.004 0.996 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.004 0.996 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.004 0.996 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.004 0.996 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.004 0.996 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.004 0.996 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.004 0.996 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.004 0.996 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.004 0.996 0.000
S92.10 Fracture of talus (closed)
0.004 0.996 0.000
H66.3 Other chronic suppurative otitis media
0.000 0.996 0.004
M05-M14 Inflammatory polyarthropathies
0.004 0.996 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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