TreeWAS – Variant ID: rs4513829

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.0 Thyrotoxicosis with diffuse goitre	0.038	0.962	0.000
S42.20 Fracture of upper end of humerus (closed)	0.037	0.963	0.000
H40.1 Primary open-angle glaucoma	0.034	0.966	0.000
E03.9 Hypothyroidism, unspecified	0.031	0.969	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.031	0.969	0.000
E03 Other hypothyroidism	0.029	0.971	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.972	0.028
E00-E07 Disorders of thyroid gland	0.028	0.972	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.027	0.973	0.000
S42.2 Fracture of upper end of humerus	0.025	0.975	0.000
E06 Thyroiditis	0.024	0.976	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.023	0.976	0.000
E05.8 Other thyrotoxicosis	0.023	0.977	0.000
E06.3 Autoimmune thyroiditis	0.023	0.977	0.000
E05.5 Thyroid crisis or storm	0.022	0.978	0.000
E05.4 Thyrotoxicosis factitia	0.022	0.978	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.022	0.978	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.022	0.978	0.000
E03.5 Myxoedema coma	0.021	0.979	0.000
E03.4 Atrophy of thyroid (acquired)	0.021	0.979	0.000
E03.3 Postinfectious hypothyroidism	0.021	0.979	0.000
E03.1 Congenital hypothyroidism without goitre	0.021	0.979	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.021	0.979	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.020	0.980	0.000
E00 Congenital iodine-deficiency syndrome	0.020	0.980	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.020	0.980	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.020	0.980	0.000
E03.8 Other specified hypothyroidism	0.020	0.980	0.000
S42.21 Fracture of upper end of humerus (open)	0.018	0.982	0.000
E06.5 Other chronic thyroiditis	0.018	0.982	0.000
E06.4 Drug-induced thyroiditis	0.018	0.982	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.018	0.982	0.000
E06.1 Subacute thyroiditis	0.018	0.982	0.000
E06.0 Acute thyroiditis	0.018	0.982	0.000
E04 Other non-toxic goitre	0.017	0.983	0.000
S42.40 Fracture of lower end of humerus (closed)	0.017	0.983	0.000
S42 Fracture of shoulder and upper arm	0.017	0.983	0.000
S42.4 Fracture of lower end of humerus	0.016	0.983	0.000
E07 Other disorders of thyroid	0.016	0.984	0.000
E06.9 Thyroiditis, unspecified	0.015	0.985	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.015	0.985	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.015	0.985	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.015	0.985	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.015	0.985	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.015	0.985	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.015	0.985	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.015	0.985	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.015	0.985	0.000
E04.0 Non-toxic diffuse goitre	0.014	0.986	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.986	0.014
E04.1 Non-toxic single thyroid nodule	0.013	0.987	0.000
E04.8 Other specified non-toxic goitre	0.012	0.987	0.000
K13 Other diseases of lip and oral mucosa	0.012	0.987	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.988	0.012
K13.6 Irritative hyperplasia of oral mucosa	0.012	0.988	0.000
E07.8 Other specified disorders of thyroid	0.012	0.988	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.012	0.988	0.000
M81.98 Osteoporosis, unspecified (Other)	0.012	0.988	0.000
S42.41 Fracture of lower end of humerus (open)	0.012	0.988	0.000
S42.3 Fracture of shaft of humerus	0.012	0.988	0.000
M80-M85 Disorders of bone density and structure	0.012	0.988	0.000
E04.9 Non-toxic goitre, unspecified	0.012	0.988	0.000
M80 Osteoporosis with pathological fracture	0.012	0.988	0.000
E07.1 Dyshormogenetic goitre	0.012	0.988	0.000
E07.0 Hypersecretion of calcitonin	0.012	0.988	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.011	0.989	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.011	0.989	0.000
M81 Osteoporosis without pathological fracture	0.011	0.989	0.000
M81.9 Osteoporosis, unspecified	0.011	0.989	0.000
M84 Disorders of continuity of bone	0.011	0.989	0.000
M85 Other disorders of bone density and structure	0.011	0.989	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.011	0.989	0.000
S42.0 Fracture of clavicle	0.010	0.990	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.010	0.990	0.000
S42.1 Fracture of scapula	0.010	0.990	0.000
M85.0 Fibrous dysplasia (monostotic)	0.010	0.990	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.009	0.991	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.009	0.991	0.000
M82 Osteoporosis in diseases classified elsewhere	0.009	0.991	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.009	0.991	0.000
K13.5 Oral submucous fibrosis	0.009	0.991	0.000
K13.3 Hairy leukoplakia	0.009	0.991	0.000
K13.1 Cheek and lip biting	0.009	0.991	0.000
M85.9 Disorder of bone density and structure, unspecified	0.009	0.991	0.000
M80.8 Other osteoporosis with pathological fracture	0.009	0.991	0.000
M84.2 Delayed union of fracture	0.009	0.991	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.009	0.991	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.009	0.991	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.009	0.991	0.000
S42.31 Fracture of shaft of humerus (open)	0.009	0.991	0.000
M83 Adult osteomalacia	0.009	0.991	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.009	0.991	0.000
M54.3 Sciatica	0.000	0.991	0.009
M80.4 Drug-induced osteoporosis with pathological fracture	0.009	0.991	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.009	0.991	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.009	0.991	0.000
M85.6 Other cyst of bone	0.009	0.991	0.000
M81.2 Osteoporosis of disuse	0.009	0.991	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.009	0.991	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.009	0.991	0.000
S42.30 Fracture of shaft of humerus (closed)	0.009	0.991	0.000
M84.4 Pathological fracture, not elsewhere classified	0.008	0.991	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.008	0.992	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.008	0.992	0.000
K05.6 Periodontal disease, unspecified	0.008	0.992	0.000
M84.0 Malunion of fracture	0.008	0.992	0.000
M81.8 Other osteoporosis	0.008	0.992	0.000
M81.6 Localised osteoporosis [Lequesne]	0.008	0.992	0.000
M81.5 Idiopathic osteoporosis	0.008	0.992	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.008	0.992	0.000
M81.1 Postoophorectomy osteoporosis	0.008	0.992	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.992	0.008
M81.0 Postmenopausal osteoporosis	0.008	0.992	0.000
M84.8 Other disorders of continuity of bone	0.008	0.992	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.008	0.992	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.008	0.992	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.008	0.992	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.008	0.992	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.008	0.992	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.008	0.992	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.008	0.992	0.000
M84.9 Disorder of continuity of bone, unspecified	0.008	0.992	0.000
M84.3 Stress fracture, not elsewhere classified	0.008	0.992	0.000
M85.5 Aneurysmal bone cyst	0.008	0.992	0.000
M85.4 Solitary bone cyst	0.008	0.992	0.000
M85.3 Osteitis condensans	0.008	0.992	0.000
M85.2 Hyperostosis of skull	0.008	0.992	0.000
M85.1 Skeletal fluorosis	0.008	0.992	0.000
M81.4 Drug-induced osteoporosis	0.008	0.992	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.008	0.992	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.008	0.992	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.008	0.992	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M84.26 Delayed union of fracture (Lower leg)	0.008	0.992	0.000
S42.01 Fracture of clavicle (open)	0.008	0.992	0.000
R41.0 Disorientation, unspecified	0.000	0.992	0.008
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.007	0.992	0.000
M82.1 Osteoporosis in endocrine disorders	0.008	0.992	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.007	0.992	0.000
M84.01 Malunion of fracture (Shoulder region)	0.008	0.992	0.000
M85.8 Other specified disorders of bone density and structure	0.008	0.992	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.007	0.993	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.007	0.993	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.993	0.007
S42.11 Fracture of scapula (open)	0.007	0.993	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.007	0.993	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.007	0.993	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.007	0.993	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.007	0.993	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.007	0.993	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.007	0.993	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.007	0.993	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.007	0.993	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.007	0.993	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.007	0.993	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.007	0.993	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.007	0.993	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.007	0.993	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.007	0.993	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.007	0.993	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.007	0.993	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.007	0.993	0.000
M06.9 Rheumatoid arthritis, unspecified	0.007	0.993	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.007	0.993	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.007	0.993	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.007	0.993	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.007	0.993	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.007	0.993	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.007	0.993	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.007	0.993	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.007	0.993	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.007	0.993	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.007	0.993	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.007	0.993	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.007	0.993	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.993	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.007	0.993	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.007	0.993	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.007	0.993	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.007	0.993	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.007	0.993	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.007	0.993	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.007	0.993	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.007	0.993	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.007	0.993	0.000
M84.28 Delayed union of fracture (Other)	0.007	0.993	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.007	0.993	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.007	0.993	0.000
M84.24 Delayed union of fracture (Hand)	0.007	0.993	0.000
M84.23 Delayed union of fracture (Forearm)	0.007	0.993	0.000
M84.22 Delayed union of fracture (Upper arm)	0.007	0.993	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.007	0.993	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.007	0.993	0.000
M84.06 Malunion of fracture (Lower leg)	0.007	0.993	0.000
K05 Gingivitis and periodontal diseases	0.007	0.993	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.007	0.993	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.007	0.993	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.007	0.993	0.000
M83.9 Adult osteomalacia, unspecified	0.006	0.993	0.000
M83.8 Other adult osteomalacia	0.006	0.993	0.000
M83.5 Other drug-induced osteomalacia in adults	0.006	0.993	0.000
M83.4 Aluminum bone disease	0.006	0.993	0.000
M83.3 Adult osteomalacia due to malnutrition	0.006	0.993	0.000
M83.2 Adult osteomalacia due to malabsorption	0.006	0.993	0.000
M83.1 Senile osteomalacia	0.006	0.993	0.000
M83.0 Puerperal osteomalacia	0.006	0.993	0.000
M54.35 Sciatica (Thoracolumbar region)	0.000	0.993	0.006
M54.34 Sciatica-Thoracic	0.000	0.993	0.006
M54.33 Sciatica-Cervicothoracic	0.000	0.993	0.006
M54.32 Sciatica-Cervical	0.000	0.993	0.006
M54.31 Sciatica-Occipit-atl-axl	0.000	0.993	0.006
M54.30 Sciatica (Multiple sites in spine)	0.000	0.993	0.006
M84.04 Malunion of fracture (Hand)	0.006	0.993	0.000
M85.69 Other cyst of bone (Site unspecified)	0.006	0.993	0.000
M85.68 Other cyst of bone (Other)	0.006	0.993	0.000
M85.66 Other cyst of bone (Lower leg)	0.006	0.993	0.000
M85.64 Other cyst of bone (Hand)	0.006	0.993	0.000
M85.63 Other cyst of bone (Forearm)	0.006	0.993	0.000
M85.62 Other cyst of bone (Upper arm)	0.006	0.993	0.000
M85.61 Other cyst of bone (Shoulder region)	0.006	0.993	0.000
M85.60 Other cyst of bone (Multiple sites)	0.006	0.993	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.006	0.993	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.006	0.993	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.006	0.993	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.006	0.993	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.006	0.993	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.006	0.993	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.006	0.993	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.006	0.993	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.006	0.993	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.006	0.993	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.006	0.993	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.006	0.993	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.006	0.993	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.006	0.993	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.993	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.006	0.993	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.006	0.993	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.006	0.993	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.006	0.993	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.006	0.993	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.006	0.993	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.006	0.993	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.006	0.993	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.006	0.993	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.993	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.006	0.993	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.006	0.993	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.006	0.993	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.006	0.993	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.006	0.993	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.006	0.993	0.000
M81.28 Osteoporosis of disuse (Other)	0.006	0.993	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.006	0.993	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.006	0.993	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.006	0.993	0.000
M81.24 Osteoporosis of disuse (Hand)	0.006	0.993	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.006	0.993	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.006	0.993	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.006	0.993	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.993	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.006	0.993	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.006	0.993	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.006	0.994	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.006	0.994	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.006	0.994	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.006	0.994	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.006	0.994	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.006	0.994	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.994	0.006
M84.09 Malunion of fracture (Site unspecified)	0.006	0.994	0.000
M84.08 Malunion of fracture (Other)	0.006	0.994	0.000
M84.02 Malunion of fracture (Upper arm)	0.006	0.994	0.000
M84.00 Malunion of fracture (Multiple sites)	0.006	0.994	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.006	0.994	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.006	0.994	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.006	0.994	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.006	0.994	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.006	0.994	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.006	0.994	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.006	0.994	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.006	0.994	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.006	0.994	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.006	0.994	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.006	0.994	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.006	0.994	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.006	0.994	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.006	0.994	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.006	0.994	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.006	0.994	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.006	0.994	0.000
M81.58 Idiopathic osteoporosis (Other)	0.006	0.994	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.006	0.994	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.006	0.994	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.006	0.994	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.006	0.994	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.006	0.994	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.006	0.994	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.006	0.994	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.006	0.994	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.006	0.994	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.006	0.994	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.006	0.994	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.006	0.994	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.006	0.994	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.006	0.994	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.006	0.994	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.006	0.994	0.000
M81.89 Other osteoporosis (Site unspecified)	0.006	0.994	0.000
M81.88 Other osteoporosis (Other)	0.006	0.994	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.86 Other osteoporosis (Lower leg)	0.006	0.994	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.84 Other osteoporosis (Hand)	0.006	0.994	0.000
M81.83 Other osteoporosis (Forearm)	0.006	0.994	0.000
M81.82 Other osteoporosis (Upper arm)	0.006	0.994	0.000
M81.81 Other osteoporosis (Shoulder region)	0.006	0.994	0.000
M81.80 Other osteoporosis (Multiple sites)	0.006	0.994	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.006	0.994	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.006	0.994	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.006	0.994	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.006	0.994	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.006	0.994	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.006	0.994	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.006	0.994	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.006	0.994	0.000
M84.88 Other disorders of continuity of bone (Other)	0.006	0.994	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.006	0.994	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.006	0.994	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.006	0.994	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.006	0.994	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.006	0.994	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.006	0.994	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.006	0.994	0.000
E07.9 Disorder of thyroid, unspecified	0.006	0.994	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.006	0.994	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.006	0.994	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.994	0.006
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
S27.1 Traumatic haemothorax	0.006	0.994	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.006	0.994	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.006	0.994	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.006	0.994	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.006	0.994	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.006	0.994	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.006	0.994	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.006	0.994	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.006	0.994	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.006	0.994	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.006	0.994	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.006	0.994	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.006	0.994	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.006	0.994	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.006	0.994	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.006	0.994	0.000
M85.18 Skeletal fluorosis (Other)	0.006	0.994	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.006	0.994	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.006	0.994	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.006	0.994	0.000
M85.14 Skeletal fluorosis (Hand)	0.006	0.994	0.000
M85.13 Skeletal fluorosis (Forearm)	0.006	0.994	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.006	0.994	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.006	0.994	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.006	0.994	0.000
M85.29 Hyperostosis of skull-Site unspec	0.006	0.994	0.000
M85.28 Hyperostosis of skull-Other	0.006	0.994	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.006	0.994	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.006	0.994	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.006	0.994	0.000
M85.24 Hyperostosis of skull-Hand	0.006	0.994	0.000
M85.23 Hyperostosis of skull-Forearm	0.006	0.994	0.000
M85.22 Hyperostosis of skull-Upper arm	0.006	0.994	0.000
M85.21 Hyperostosis of skull-Shldr region	0.006	0.994	0.000
M85.20 Hyperostosis of skull-Mult sites	0.006	0.994	0.000
M85.39 Osteitis condensans (Site unspecified)	0.006	0.994	0.000
M85.38 Osteitis condensans (Other)	0.006	0.994	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.006	0.994	0.000
M85.36 Osteitis condensans (Lower leg)	0.006	0.994	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.006	0.994	0.000
M85.34 Osteitis condensans (Hand)	0.006	0.994	0.000
M85.33 Osteitis condensans (Forearm)	0.006	0.994	0.000
M85.32 Osteitis condensans (Upper arm)	0.006	0.994	0.000
M85.31 Osteitis condensans (Shoulder region)	0.006	0.994	0.000
M85.30 Osteitis condensans (Multiple sites)	0.006	0.994	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.006	0.994	0.000
M85.48 Solitary bone cyst (Other)	0.006	0.994	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.006	0.994	0.000
M85.46 Solitary bone cyst (Lower leg)	0.006	0.994	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.006	0.994	0.000
M85.44 Solitary bone cyst (Hand)	0.006	0.994	0.000
M85.43 Solitary bone cyst (Forearm)	0.006	0.994	0.000
M85.42 Solitary bone cyst (Upper arm)	0.006	0.994	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.006	0.994	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.006	0.994	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.006	0.994	0.000
M85.58 Aneurysmal bone cyst (Other)	0.006	0.994	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.006	0.994	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.006	0.994	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.006	0.994	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.006	0.994	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.006	0.994	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.006	0.994	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.006	0.994	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.006	0.994	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.006	0.994	0.000
M81.48 Drug-induced osteoporosis (Other)	0.006	0.994	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.006	0.994	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.006	0.994	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.006	0.994	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.006	0.994	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.006	0.994	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.006	0.994	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.006	0.994	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.006	0.994	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.006	0.994	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.006	0.994	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
S42.00 Fracture of clavicle (closed)	0.006	0.994	0.000
S27 Injury of other and unspecified intrathoracic organs	0.006	0.994	0.000
K37 Unspecified appendicitis	0.006	0.994	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.006	0.994	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.006	0.994	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.006	0.994	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.006	0.994	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.006	0.994	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.006	0.994	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.006	0.994	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.006	0.994	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.006	0.994	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.006	0.994	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.994	0.006
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.005	0.994	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.006	0.994	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.006	0.994	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.006	0.994	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.006	0.994	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.006	0.994	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.006	0.994	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.994	0.006
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.006	0.994	0.000
S40-S49 Injuries to the shoulder and upper arm	0.006	0.994	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.005	0.994	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations