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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4516988
log Bayes Factor = 46.3141
Chromosome 6   position 31,176,602  (GRCh37) Explore rs4516988 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
G35 Multiple sclerosis
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
M45.X9 Ankylosing spondylitis (Site unspecified)
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.006 0.994
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
E10.1 With ketoacidosis
0.000 0.015 0.985
E00-E07 Disorders of thyroid gland
0.000 0.029 0.970
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.031 0.969
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.050 0.950
M45 Ankylosing spondylitis
0.942 0.058 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.103 0.897
E10.2 With renal complications
0.000 0.113 0.887
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.881 0.119 0.000
M06.9 Rheumatoid arthritis, unspecified
0.877 0.123 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.873 0.127 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.870 0.130 0.000
E13 Other specified diabetes mellitus
0.000 0.144 0.856
E10.5 With peripheral circulatory complications
0.000 0.155 0.845
E10.9 Without complications
0.000 0.156 0.844
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.158 0.842
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.174 0.826
E06 Thyroiditis
0.000 0.190 0.810
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.798 0.202 0.000
E14 Unspecified diabetes mellitus
0.000 0.203 0.797
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.792 0.208 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.790 0.210 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.210 0.790
E10.8 With unspecified complications
0.000 0.217 0.783
E05.8 Other thyrotoxicosis
0.000 0.239 0.761
E10.0 With coma
0.000 0.246 0.754
E13.9 Without complications
0.000 0.246 0.754
E10.6 With other specified complications
0.000 0.248 0.752
E10.4 With neurological complications
0.000 0.249 0.751
E14.3 With ophthalmic complications
0.000 0.255 0.745
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.744 0.256 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.261 0.739
E40-E46 Malnutrition
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E06.9 Thyroiditis, unspecified
0.000 0.288 0.712
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.304 0.696
E00 Congenital iodine-deficiency syndrome
0.000 0.304 0.696
E05.5 Thyroid crisis or storm
0.000 0.305 0.694
E05.4 Thyrotoxicosis factitia
0.000 0.305 0.694
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.305 0.694
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.305 0.694
M06 Other rheumatoid arthritis
0.693 0.307 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.687 0.313 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.681 0.318 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.675 0.325 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.675 0.325 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.675 0.325 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.675 0.325 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.675 0.325 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.675 0.325 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.675 0.325 0.000
E14.4 With neurological complications
0.000 0.349 0.651
E16.1 Other hypoglycaemia
0.000 0.367 0.633
E20-E35 Disorders of other endocrine glands
0.000 0.371 0.629
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.624 0.376 0.000
E66 Obesity
0.000 0.386 0.614
E13.8 With unspecified complications
0.000 0.386 0.613
E13.7 With multiple complications
0.000 0.386 0.613
E13.6 With other specified complications
0.000 0.386 0.613
E13.5 With peripheral circulatory complications
0.000 0.386 0.613
E13.4 With neurological complications
0.000 0.386 0.613
E13.3 With ophthalmic complications
0.000 0.386 0.613
E13.2 With renal complications
0.000 0.386 0.613
E13.1 With ketoacidosis
0.000 0.386 0.613
E13.0 With coma
0.000 0.386 0.613
M06.98 Rheumatoid arthritis, unspecified (Other)
0.612 0.387 0.000
E06.3 Autoimmune thyroiditis
0.000 0.389 0.611
M06.3 Rheumatoid nodule
0.608 0.391 0.000
M06.0 Seronegative rheumatoid arthritis
0.604 0.396 0.000
E65 Localised adiposity
0.000 0.397 0.603
K90 Intestinal malabsorption
0.000 0.417 0.583
E06.4 Drug-induced thyroiditis
0.000 0.419 0.581
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.419 0.581
E06.1 Subacute thyroiditis
0.000 0.419 0.581
E06.0 Acute thyroiditis
0.000 0.419 0.581
E14.8 With unspecified complications
0.000 0.428 0.572
E14.7 With multiple complications
0.000 0.428 0.572
E14.2 Withrenal complications
0.000 0.428 0.572
E14.1 With ketoacidosis
0.000 0.428 0.572
E14.0 With coma
0.000 0.428 0.572
E67 Other hyperalimentation
0.000 0.434 0.566
E68 Sequelae of hyperalimentation
0.000 0.434 0.566
E66.8 Other obesity
0.000 0.438 0.562
M06.34 Rheumatoid nodule (Hand)
0.561 0.439 0.000
E14.5 With peripheral circulatory complications
0.000 0.462 0.537
E50-E64 Other nutritional deficiencies
0.000 0.465 0.535
E34 Other endocrine disorders
0.000 0.467 0.533
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.530 0.470 0.000
E14.6 With other specified complications
0.000 0.479 0.521
E46 Unspecified protein-energy malnutrition
0.000 0.482 0.518
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.486 0.514
E45 Retarded development following protein-energy malnutrition
0.000 0.486 0.514
E43 Unspecified severe protein-energy malnutrition
0.000 0.486 0.514
E42 Marasmic kwashiorkor
0.000 0.486 0.514
E41 Nutritional marasmus
0.000 0.486 0.514
E40 Kwashiorkor
0.000 0.486 0.514
E26 Hyperaldosteronism
0.000 0.486 0.514
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.496 0.504
E24 Cushing's syndrome
0.000 0.496 0.504
E66.0 Obesity due to excess calories
0.000 0.497 0.503
E06.5 Other chronic thyroiditis
0.000 0.500 0.499
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.501 0.499
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.501 0.499
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.501 0.499
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.501 0.499
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.501 0.499
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.501 0.499
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.501 0.499
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.501 0.499
M06.8 Other specified rheumatoid arthritis
0.497 0.503 0.000
M06.2 Rheumatoid bursitis
0.497 0.503 0.000
M06.1 Adult-onset Still's disease
0.497 0.503 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.491 0.509 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.509 0.491
M06.4 Inflammatory polyarthropathy
0.485 0.515 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.481 0.518 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.522 0.478
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.531 0.469
K90.9 Intestinal malabsorption, unspecified
0.000 0.539 0.461
E34.9 Endocrine disorder, unspecified
0.000 0.541 0.459
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.549 0.451
E32 Diseases of thymus
0.000 0.549 0.451
E31 Polyglandular dysfunction
0.000 0.549 0.451
E30 Disorders of puberty, not elsewhere classified
0.000 0.549 0.451
E25 Adrenogenital disorders
0.000 0.549 0.451
E27 Other disorders of adrenal gland
0.000 0.551 0.449
M06.37 Rheumatoid nodule (Ankle and foot)
0.444 0.556 0.000
E66.1 Drug-induced obesity
0.000 0.560 0.440
M06.39 Rheumatoid nodule (Site unspecified)
0.436 0.564 0.000
M06.38 Rheumatoid nodule (Other)
0.436 0.564 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.436 0.564 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.436 0.564 0.000
M06.33 Rheumatoid nodule (Forearm)
0.436 0.564 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.436 0.564 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.436 0.564 0.000
E22 Hyperfunction of pituitary gland
0.000 0.565 0.435
E20 Hypoparathyroidism
0.000 0.566 0.434
M06.08 Seronegative rheumatoid arthritis (Other)
0.433 0.567 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.433 0.567 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.433 0.567 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.433 0.567 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.433 0.567 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.433 0.567 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.433 0.567 0.000
E26.0 Primary hyperaldosteronism
0.000 0.568 0.432
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.575 0.425
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.579 0.420
K90.3 Pancreatic steatorrhoea
0.000 0.581 0.418
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.581 0.418
K90.1 Tropical sprue
0.000 0.581 0.418
E27.1 Primary adrenocortical insufficiency
0.000 0.582 0.418
E11.3 With ophthalmic complications
0.000 0.582 0.418
E34.0 Carcinoid syndrome
0.000 0.586 0.414
E24.9 Cushing's syndrome, unspecified
0.000 0.588 0.412
E29 Testicular dysfunction
0.000 0.591 0.409
E21.0 Primary hyperparathyroidism
0.000 0.591 0.409
E67.8 Other specified hyperalimentation
0.000 0.594 0.406
E67.3 Hypervitaminosis D
0.000 0.594 0.406
E67.2 Megavitamin-B6 syndrome
0.000 0.594 0.406
E67.1 Hypercarotenaemia
0.000 0.594 0.406
E67.0 Hypervitaminosis A
0.000 0.594 0.406
E55 Vitamin D deficiency
0.000 0.610 0.390
E24.0 Pituitary-dependent Cushing's disease
0.000 0.616 0.384
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.616 0.384
E63 Other nutritional deficiencies
0.000 0.616 0.384
E56 Other vitamin deficiencies
0.000 0.616 0.384
E51 Thiamine deficiency
0.000 0.616 0.384
E50 Vitamin A deficiency
0.000 0.616 0.384
E60 Dietary zinc deficiency
0.000 0.616 0.384
E59 Dietary selenium deficiency
0.000 0.616 0.384
E54 Ascorbic acid deficiency
0.000 0.616 0.384
E52 Niacin deficiency [pellagra]
0.000 0.616 0.384
E11.8 With unspecified complications
0.000 0.617 0.383
E11.6 With other specified complications
0.000 0.617 0.383
E34.5 Androgen resistance syndrome
0.000 0.618 0.382
E34.4 Constitutional tall stature
0.000 0.618 0.382
E34.3 Short stature, not elsewhere classified
0.000 0.618 0.382
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.618 0.382
E34.1 Other hypersecretion of intestinal hormones
0.000 0.618 0.382
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.380 0.620 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.379 0.621 0.000
M45-M49 Spondylopathies
0.378 0.622 0.000
E11.5 With peripheral circulatory complications
0.000 0.624 0.376
E44.1 Mild protein-energy malnutrition
0.000 0.631 0.369
E44.0 Moderate protein-energy malnutrition
0.000 0.631 0.369
E26.9 Hyperaldosteronism, unspecified
0.000 0.631 0.369
E26.8 Other hyperaldosteronism
0.000 0.631 0.369
E26.1 Secondary hyperaldosteronism
0.000 0.631 0.369
E22.1 Hyperprolactinaemia
0.000 0.637 0.363
K90.8 Other intestinal malabsorption
0.000 0.638 0.362
E21.4 Other specified disorders of parathyroid gland
0.000 0.638 0.362
E21.2 Other hyperparathyroidism
0.000 0.638 0.362
G37 Other demyelinating diseases of central nervous system
0.000 0.638 0.362
E24.8 Other Cushing's syndrome
0.000 0.639 0.361
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.639 0.361
E24.3 Ectopic ACTH syndrome
0.000 0.639 0.361
E24.1 Nelson's syndrome
0.000 0.639 0.361
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.360 0.640 0.000
E58 Dietary calcium deficiency
0.000 0.641 0.358
M46 Other inflammatory spondylopathies
0.358 0.642 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.356 0.643 0.000
M06.18 Adult-onset Still's disease (Other)
0.356 0.643 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.356 0.643 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.356 0.643 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.356 0.643 0.000
M06.14 Adult-onset Still's disease (Hand)
0.356 0.643 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.356 0.643 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.356 0.643 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.356 0.643 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.356 0.643 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.356 0.643 0.000
M06.28 Rheumatoid bursitis (Other)
0.356 0.643 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.356 0.643 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.356 0.643 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.356 0.643 0.000
M06.24 Rheumatoid bursitis (Hand)
0.356 0.643 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.356 0.643 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.356 0.643 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.356 0.643 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.356 0.643 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.356 0.643 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.356 0.643 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.356 0.643 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.356 0.643 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.356 0.643 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.356 0.643 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.356 0.643 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.356 0.643 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.356 0.643 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.356 0.643 0.000
E34.8 Other specified endocrine disorders
0.000 0.644 0.355
M06.48 Inflammatory polyarthropathy (Other)
0.348 0.652 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.348 0.652 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.348 0.652 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.348 0.652 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.348 0.652 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.348 0.652 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.348 0.652 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.348 0.652 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.653 0.346
E07 Other disorders of thyroid
0.001 0.655 0.343
M46.9 Inflammatory spondylopathy, unspecified
0.343 0.657 0.000
E11.7 With multiple complications
0.000 0.657 0.343
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.337 0.663 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.663 0.336
G36 Other acute disseminated demyelination
0.000 0.664 0.336
E61 Deficiency of other nutrient elements
0.000 0.667 0.333
E21.3 Hyperparathyroidism, unspecified
0.000 0.671 0.329
E11.1 With ketoacidosis
0.000 0.674 0.326
E22.0 Acromegaly and pituitary gigantism
0.000 0.675 0.325
E25.9 Adrenogenital disorder, unspecified
0.000 0.676 0.324
E25.8 Other adrenogenital disorders
0.000 0.676 0.324
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.676 0.324
E30.9 Disorder of puberty, unspecified
0.000 0.676 0.324
E30.8 Other disorders of puberty
0.000 0.676 0.324
E30.1 Precocious puberty
0.000 0.676 0.324
E30.0 Delayed puberty
0.000 0.676 0.324
E31.9 Polyglandular dysfunction, unspecified
0.000 0.676 0.324
E31.8 Other polyglandular dysfunction
0.000 0.676 0.324
E31.1 Polyglandular hyperfunction
0.000 0.676 0.324
E31.0 Autoimmune polyglandular failure
0.000 0.676 0.324
E32.9 Disease of thymus, unspecified
0.000 0.676 0.324
E32.8 Other diseases of thymus
0.000 0.676 0.324
E32.1 Abscess of thymus
0.000 0.676 0.324
E32.0 Persistent hyperplasia of thymus
0.000 0.676 0.324
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.676 0.324
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.676 0.324
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.676 0.324
E27.5 Adrenomedullary hyperfunction
0.000 0.678 0.322
E27.0 Other adrenocortical overactivity
0.000 0.678 0.322
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.320 0.680 0.000
E53 Deficiency of other B group vitamins
0.000 0.686 0.314
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.688 0.312
E22.8 Other hyperfunction of pituitary gland
0.000 0.688 0.312
E04 Other non-toxic goitre
0.000 0.688 0.312
E20.8 Other hypoparathyroidism
0.000 0.689 0.311
E20.1 Pseudohypoparathyroidism
0.000 0.689 0.311
E20.0 Idiopathic hypoparathyroidism
0.000 0.689 0.311
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.691 0.309
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.696 0.304
E20.9 Hypoparathyroidism, unspecified
0.000 0.706 0.294
E29.9 Testicular dysfunction, unspecified
0.000 0.706 0.293
E29.8 Other testicular dysfunction
0.000 0.706 0.293
E29.0 Testicular hyperfunction
0.000 0.706 0.293
E27.9 Disorder of adrenal gland, unspecified
0.000 0.707 0.293
E55.9 Vitamin D deficiency, unspecified
0.000 0.714 0.286
M46.2 Osteomyelitis of vertebra
0.285 0.715 0.000
E11.4 With neurological complications
0.000 0.717 0.283
E55.0 Rickets, active
0.000 0.720 0.280
E50.9 Vitamin A deficiency, unspecified
0.000 0.725 0.275
E50.8 Other manifestations of vitamin A deficiency
0.000 0.725 0.275
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.725 0.275
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.725 0.275
E50.5 Vitamin A deficiency with night blindness
0.000 0.725 0.275
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.725 0.275
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.725 0.275
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.725 0.275
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.725 0.275
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.725 0.275
E51.9 Thiamine deficiency, unspecified
0.000 0.725 0.275
E51.8 Other manifestations of thiamine deficiency
0.000 0.725 0.275
E51.2 Wernicke's encephalopathy
0.000 0.725 0.275
E51.1 Beriberi
0.000 0.725 0.275
E56.9 Vitamin deficiency, unspecified
0.000 0.725 0.275
E56.8 Deficiency of other vitamins
0.000 0.725 0.275
E56.1 Deficiency of vitamin K
0.000 0.725 0.275
E56.0 Deficiency of vitamin E
0.000 0.725 0.275
E63.9 Nutritional deficiency, unspecified
0.000 0.725 0.275
E63.8 Other specified nutritional deficiencies
0.000 0.725 0.275
E63.1 Imbalance of constituents of food intake
0.000 0.725 0.275
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.725 0.275
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.725 0.275
E64.8 Sequelae of other nutritional deficiencies
0.000 0.725 0.275
E64.3 Sequelae of rickets
0.000 0.725 0.275
E64.2 Sequelae of vitamin C deficiency
0.000 0.725 0.275
E64.1 Sequelae of vitamin A deficiency
0.000 0.725 0.275
E64.0 Sequelae of protein-energy malnutrition
0.000 0.725 0.275
E03 Other hypothyroidism
0.030 0.731 0.238
E11.0 With coma
0.000 0.732 0.268
E27.8 Other specified disorders of adrenal gland
0.000 0.732 0.267
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.261 0.739 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.740 0.259
G37.4 Subacute necrotising myelitis
0.000 0.740 0.259
G37.2 Central pontine myelinolysis
0.000 0.740 0.259
G37.1 Central demyelination of corpus callosum
0.000 0.740 0.259
G37.0 Diffuse sclerosis
0.000 0.740 0.259
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.743 0.257
M46.8 Other specified inflammatory spondylopathies
0.257 0.743 0.000
M46.5 Other infective spondylopathies
0.257 0.743 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.257 0.743 0.000
M46.0 Spinal enthesopathy
0.257 0.743 0.000
M49 Spondylopathies in diseases classified elsewhere
0.254 0.746 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.253 0.747 0.000
E29.1 Testicular hypofunction
0.000 0.749 0.251
E04.0 Non-toxic diffuse goitre
0.000 0.749 0.251
E27.2 Addisonian crisis
0.000 0.751 0.249
E07.1 Dyshormogenetic goitre
0.001 0.753 0.246
E07.0 Hypersecretion of calcitonin
0.001 0.753 0.246
M46.4 Discitis, unspecified
0.247 0.753 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.246 0.754 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.246 0.754 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.246 0.754 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.246 0.754 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.246 0.754 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.755 0.245
G36.9 Acute disseminated demyelination, unspecified
0.000 0.759 0.241
G36.8 Other specified acute disseminated demyelination
0.000 0.759 0.241
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.759 0.241
G36.0 Neuromyelitis optica [Devic]
0.000 0.759 0.241
E61.9 Deficiency of nutrient element, unspecified
0.000 0.761 0.239
E61.8 Deficiency of other specified nutrient elements
0.000 0.761 0.239
E61.7 Deficiency of multiple nutrient elements
0.000 0.761 0.239
E61.6 Vanadium deficiency
0.000 0.761 0.239
E61.5 Molybdenum deficiency
0.000 0.761 0.239
E61.4 Chromium deficiency
0.000 0.761 0.239
E61.3 Manganese deficiency
0.000 0.761 0.239
E61.0 Copper deficiency
0.000 0.761 0.239
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.233 0.767 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.233 0.767 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.232 0.768 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.772 0.228
E61.2 Magnesium deficiency
0.000 0.774 0.226
E53.1 Pyridoxine deficiency
0.000 0.775 0.225
E53.0 Riboflavin deficiency
0.000 0.775 0.225
E11.2 With renal complications
0.000 0.775 0.225
E23 Hypofunction and other disorders of pituitary gland
0.000 0.776 0.224
E04.8 Other specified non-toxic goitre
0.000 0.776 0.224
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.784 0.216
E61.1 Iron deficiency
0.000 0.794 0.206
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.205 0.795 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.205 0.795 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.205 0.795 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.205 0.795 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.205 0.795 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.205 0.795 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.205 0.795 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.205 0.795 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.205 0.795 0.000
E03.5 Myxoedema coma
0.022 0.807 0.171
E03.4 Atrophy of thyroid (acquired)
0.022 0.807 0.171
E03.3 Postinfectious hypothyroidism
0.022 0.807 0.171
E03.1 Congenital hypothyroidism without goitre
0.022 0.807 0.171
E03.0 Congenital hypothyroidism with diffuse goitre
0.022 0.807 0.171
E07.8 Other specified disorders of thyroid
0.001 0.808 0.190
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.188 0.812 0.000
E28 Ovarian dysfunction
0.003 0.813 0.184
M46.09 Spinal enthesopathy (Site unspecified)
0.184 0.816 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.184 0.816 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.184 0.816 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.184 0.816 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.184 0.816 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.184 0.816 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.184 0.816 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.184 0.816 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.184 0.816 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.184 0.816 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.184 0.816 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.184 0.816 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.184 0.816 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.184 0.816 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.184 0.816 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.184 0.816 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.184 0.816 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.184 0.816 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.184 0.816 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.184 0.816 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.184 0.816 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.184 0.816 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.184 0.816 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.184 0.816 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.184 0.816 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.184 0.816 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.184 0.816 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.184 0.816 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.184 0.816 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.184 0.816 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.184 0.816 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.184 0.816 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.184 0.816 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.184 0.816 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.184 0.816 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.184 0.816 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.184 0.816 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.184 0.816 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.184 0.816 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.184 0.816 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.816 0.184
M49.8 Spondylopathy in other diseases classified elsewhere
0.182 0.818 0.000
M49.4 Neuropathic spondylopathy
0.182 0.818 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.182 0.818 0.000
M49.2 Enterobacterial spondylitis
0.182 0.818 0.000
M49.1 Brucella spondylitis
0.182 0.818 0.000
M49.0 Tuberculosis of spine
0.182 0.818 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.179 0.821 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.177 0.823 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.177 0.823 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.177 0.823 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.177 0.823 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.177 0.823 0.000
M46.42 Discitis, unspecified (Cervical region)
0.177 0.823 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.177 0.823 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.177 0.823 0.000
M48 Other spondylopathies
0.176 0.824 0.000
E23.6 Other disorders of pituitary gland
0.000 0.824 0.175
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.830 0.170
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.167 0.833 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.167 0.833 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.167 0.833 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.167 0.833 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.167 0.833 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.167 0.833 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.167 0.833 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.167 0.833 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.167 0.833 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.023 0.834 0.143
M49.5 Collapsed vertebra in diseases classified elsewhere
0.165 0.835 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.165 0.835 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.839 0.161
E23.1 Drug-induced hypopituitarism
0.000 0.839 0.161
E03.8 Other specified hypothyroidism
0.023 0.842 0.135
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.143 0.856 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.865 0.134
E28.9 Ovarian dysfunction, unspecified
0.002 0.865 0.132
E28.8 Other ovarian dysfunction
0.002 0.865 0.132
E28.1 Androgen excess
0.002 0.865 0.132
E28.0 Oestrogen excess
0.002 0.865 0.132
M48.8 Other specified spondylopathies
0.132 0.867 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.131 0.869 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.131 0.869 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.131 0.869 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.131 0.869 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.131 0.869 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.131 0.869 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.131 0.869 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.131 0.869 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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