TreeWAS – Variant ID: rs452036

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.881	0.119
N43.3 Hydrocele, unspecified	0.000	0.947	0.053
I60 Subarachnoid haemorrhage	0.049	0.951	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.048	0.952	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.047	0.953	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.044	0.956	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.044	0.956	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.044	0.956	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.044	0.956	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.043	0.957	0.000
Y52 Agents primarily affecting the cardiovascular system	0.042	0.958	0.000
Y52.1 Calcium-channel blockers	0.041	0.959	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.040	0.960	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.039	0.961	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.037	0.963	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.037	0.963	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.035	0.964	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.032	0.968	0.000
I60.8 Other subarachnoid haemorrhage	0.032	0.968	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.030	0.970	0.000
Y52.7 Peripheral vasodilators	0.030	0.970	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.030	0.970	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.030	0.970	0.000
N73.6 Female pelvic peritoneal adhesions	0.029	0.971	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.027	0.973	0.000
N73 Other female pelvic inflammatory diseases	0.025	0.975	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.022	0.978	0.000
N73.5 Female pelvic peritonitis, unspecified	0.021	0.979	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.019	0.981	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.018	0.982	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.018	0.982	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.018	0.982	0.000
N73.4 Female chronic pelvic peritonitis	0.018	0.982	0.000
N73.3 Female acute pelvic peritonitis	0.018	0.982	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.018	0.982	0.000
N43 Hydrocele and spermatocele	0.000	0.982	0.018
N43.2 Other hydrocele	0.000	0.987	0.013
N43.0 Encysted hydrocele	0.000	0.987	0.013
N43.4 Spermatocele	0.000	0.987	0.012
N43.1 Infected hydrocele	0.000	0.988	0.011
N02.9 Unspecified	0.000	0.989	0.011
N70-N77 Inflammatory diseases of female pelvic organs	0.009	0.991	0.000
N70 Salpingitis and oophoritis	0.009	0.991	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.009	0.991	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.008	0.992	0.000
N70.1 Chronic salpingitis and oophoritis	0.008	0.992	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.007	0.993	0.000
N70.0 Acute salpingitis and oophoritis	0.007	0.993	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.007	0.993	0.000
N02 Recurrent and persistent haematuria	0.000	0.993	0.007
N71 Inflammatory disease of uterus, except cervix	0.007	0.993	0.000
H83.0 Labyrinthitis	0.007	0.993	0.000
N02.8 Other	0.000	0.993	0.007
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.993	0.007
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.006	0.993	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
N76 Other inflammation of vagina and vulva	0.006	0.994	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.994	0.006
N76.2 Acute vulvitis	0.006	0.994	0.000
F80.1 Expressive language disorder	0.000	0.994	0.006
N71.0 Acute inflammatory disease of uterus	0.006	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
R76.8 Other specified abnormal immunological findings in serum	0.006	0.994	0.000
F03 Unspecified dementia	0.000	0.994	0.006
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.994	0.006
N76.6 Ulceration of vulva	0.005	0.995	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.005	0.995	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.005	0.995	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.005	0.995	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.005	0.995	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.005	0.995	0.000
N74.0 Tuberculous infection of cervix uteri	0.005	0.995	0.000
N76.8 Other specified inflammation of vagina and vulva	0.005	0.995	0.000
L03.2 Cellulitis of face	0.005	0.995	0.000
N76.5 Ulceration of vagina	0.005	0.995	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.000	0.995	0.005
N02.6 Dense deposit disease	0.000	0.995	0.005
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.995	0.005
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.995	0.005
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.995	0.005
N02.1 Focal and segmental glomerular lesions	0.000	0.995	0.005
N76.1 Subacute and chronic vaginitis	0.005	0.995	0.000
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
N02.0 Minor glomerular abnormality	0.000	0.995	0.005
T42.3 Barbiturates	0.005	0.995	0.000
N02.2 Diffuse membranous glomerulonephritis	0.000	0.995	0.005
H83 Other diseases of inner ear	0.005	0.995	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
Z37.2 Twins, both liveborn	0.000	0.995	0.005
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.995	0.005
N39.8 Other specified disorders of urinary system	0.000	0.995	0.005
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.995	0.005
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.995	0.000
C16.2 Body of stomach	0.005	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.995	0.000
N75 Diseases of Bartholin's gland	0.005	0.995	0.000
H83.3 Noise effects on inner ear	0.004	0.995	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.996	0.004
N71.1 Chronic inflammatory disease of uterus	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
D69.6 Thrombocytopenia, unspecified	0.004	0.996	0.000
H83.9 Disease of inner ear, unspecified	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
C16.9 Stomach, unspecified	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.004	0.996	0.000
T92 Sequelae of injuries of upper limb	0.000	0.996	0.004
N75.8 Other diseases of Bartholin's gland	0.004	0.996	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.996	0.004
H83.2 Labyrinthine dysfunction	0.004	0.996	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.996	0.004
C16.6 Greater curvature of stomach, unspecified	0.004	0.996	0.000
H83.1 Labyrinthine fistula	0.004	0.996	0.000
C16.3 Pyloric antrum	0.004	0.996	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.004	0.996	0.000
C22.1 Intrahepatic bile duct carcinoma	0.004	0.996	0.000
F80 Specific developmental disorders of speech and language	0.000	0.996	0.004
H83.8 Other specified diseases of inner ear	0.003	0.996	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.996	0.004
F43.0 Acute stress reaction	0.004	0.996	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.003	0.996	0.000
C16.1 Fundus of stomach	0.003	0.996	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.997	0.003
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
T92.1 Sequelae of fracture of arm	0.000	0.997	0.003
T42.1 Iminostilbenes	0.003	0.997	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.997	0.003
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
C16.4 Pylorus	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.997	0.003
N76.0 Acute vaginitis	0.003	0.997	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.003	0.997	0.000
F43.2 Adjustment disorders	0.003	0.997	0.000
M06.34 Rheumatoid nodule (Hand)	0.003	0.997	0.000
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.997	0.003
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
H02.1 Ectropion of eyelid	0.000	0.997	0.003
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.997	0.003
N76.3 Subacute and chronic vulvitis	0.003	0.997	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.003	0.997	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
R76 Other abnormal immunological findings in serum	0.003	0.997	0.000
T92.0 Sequelae of open wound of upper limb	0.000	0.997	0.003
M06.30 Rheumatoid nodule (Multiple sites)	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
C16.0 Cardia	0.003	0.997	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.003	0.997	0.000
M06.3 Rheumatoid nodule	0.003	0.997	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.000	0.997	0.003
F80.8 Other developmental disorders of speech and language	0.000	0.997	0.003
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.000	0.997	0.003
F80.2 Receptive language disorder	0.000	0.997	0.003
F80.0 Specific speech articulation disorder	0.000	0.997	0.003
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.997	0.003
Y42.4 Oral contraceptives	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.000	0.997	0.003
D69.0 Allergic purpura	0.003	0.997	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.997	0.003
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.997	0.003
H72.1 Attic perforation of tympanic membrane	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
D69.8 Other specified haemorrhagic conditions	0.002	0.997	0.000
D69.1 Qualitative platelet defects	0.002	0.997	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.997	0.003
R76.9 Abnormal immunological finding in serum, unspecified	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.002	0.997	0.000
L71.1 Rhinophyma	0.000	0.997	0.003
H72.0 Central perforation of tympanic membrane	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
F43.8 Other reactions to severe stress	0.002	0.997	0.000
Z01.6 Radiological examination, not elsewhere classified	0.003	0.997	0.000
O30.0 Twin pregnancy	0.000	0.997	0.003
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.997	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.001	0.998	0.002
R76.0 Raised antibody titer	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.002	0.998	0.000
R76.2 False-positive serological test for syphilis	0.002	0.998	0.000
R76.1 Abnormal reaction to tuberculin test	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.000	0.998	0.002
C67.9 Bladder, unspecified	0.002	0.998	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.002	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.002	0.998	0.000
M06.38 Rheumatoid nodule (Other)	0.002	0.998	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.002	0.998	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.002	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.002	0.998	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
F42 Obsessive-compulsive disorder	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
Z50.5 Speech therapy	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
F42.2 Mixed obsessional thoughts and acts	0.002	0.998	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
L71 Rosacea	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.002
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
F42.8 Other obsessive-compulsive disorders	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
R09.0 Asphyxia	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.000	0.998	0.002
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.001	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
L52 Erythema nodosum	0.002	0.998	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
H06.2 Dysthyroid exophthalmos	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.998	0.002
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.998	0.002
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
L71.8 Other rosacea	0.000	0.998	0.002
L71.0 Perioral dermatitis	0.000	0.998	0.002
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
N90.5 Atrophy of vulva	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.002	0.998	0.000
F80-F89 Disorders of psychological development	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.001	0.998	0.000
Y57.4 Pharmaceutical excipients	0.001	0.998	0.000
Y57.3 Alcohol deterrents	0.001	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.998	0.000
Y57.1 Lipotropic drugs	0.001	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
D13.5 Extrahepatic bile ducts	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.001	0.998	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.001	0.998	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.001	0.998	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.001	0.998	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.001	0.998	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.001	0.998	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.001	0.998	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.001	0.998	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.001	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
Y41.0 Sulphonamides	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
G00.8 Other bacterial meningitis	0.000	0.998	0.001
G00.3 Staphylococcal meningitis	0.000	0.998	0.001
G00.2 Streptococcal meningitis	0.000	0.998	0.001
G00.0 Haemophilus meningitis	0.000	0.998	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
O16 Unspecified maternal hypertension	0.000	0.998	0.002
F81 Specific developmental disorders of scholastic skills	0.000	0.998	0.001
E10.4 With neurological complications	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.001	0.998	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.000	0.998	0.001
Z50.4 Psychotherapy, not elsewhere classified	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.000	0.998	0.001
T79.5 Traumatic anuria	0.000	0.998	0.001
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.998	0.001
T79.1 Fat embolism (traumatic)	0.000	0.998	0.001
T79.0 Air embolism (traumatic)	0.000	0.998	0.001
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Z04.5 Examination and observation following other inflicted injury	0.001	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.001	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.999	0.001
O43.8 Other placental disorders	0.001	0.999	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
K09.9 Cyst of oral region, unspecified	0.000	0.999	0.001
F89 Unspecified disorder of psychological development	0.000	0.999	0.001
F88 Other disorders of psychological development	0.000	0.999	0.001
F83 Mixed specific developmental disorders	0.000	0.999	0.001
F82 Specific developmental disorder of motor function	0.000	0.999	0.001
S42.00 Fracture of clavicle (closed)	0.001	0.999	0.000
C77.9 Lymph node, unspecified	0.000	0.999	0.001
E10.5 With peripheral circulatory complications	0.001	0.999	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.999	0.001
C67.0 Trigone of bladder	0.001	0.999	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.999	0.001
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.001	0.999	0.000
Z89.9 Acquired absence of limb, unspecified	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.000	0.999	0.001
H61.2 Impacted cerumen	0.000	0.999	0.001
N75.0 Cyst of Bartholin's gland	0.001	0.999	0.000
T79.4 Traumatic shock	0.000	0.999	0.001
Y40.4 Tetracyclines	0.001	0.999	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.999	0.001
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.001	0.999	0.000
C67.8 Overlapping lesion of bladder	0.001	0.999	0.000
D13.0 Oesophagus	0.001	0.999	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.001	0.999	0.000
Y46.4 Iminostilbenes	0.001	0.999	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.999	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.999	0.000
E10.2 With renal complications	0.001	0.999	0.000
F81.8 Other developmental disorders of scholastic skills	0.000	0.999	0.001
F81.3 Mixed disorder of scholastic skills	0.000	0.999	0.001
F81.2 Specific disorder of arithmetical skills	0.000	0.999	0.001
F81.1 Specific spelling disorder	0.000	0.999	0.001
F81.0 Specific reading disorder	0.000	0.999	0.001
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.999	0.001
Y40 Systemic antibiotics	0.001	0.999	0.000
H80-H83 Diseases of inner ear	0.001	0.999	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.999	0.000
D13.3 Other and unspecified parts of small intestine	0.001	0.999	0.000
G93.9 Disorder of brain, unspecified	0.001	0.999	0.000
C67.6 Ureteric orifice	0.001	0.999	0.000
F45.0 Somatisation disorder	0.001	0.999	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.001	0.999	0.000
M21.8 Other specified acquired deformities of limbs	0.001	0.999	0.000
T81.9 Unspecified complication of procedure	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.001	0.999	0.000
F84 Pervasive developmental disorders	0.000	0.999	0.001
S71.1 Open wound of thigh	0.000	0.999	0.001
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.999	0.001
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.999	0.001
E26.0 Primary hyperaldosteronism	0.000	0.999	0.001
H70.9 Mastoiditis, unspecified	0.000	0.999	0.001
Z39.0 Care and examination immediately after delivery	0.000	0.999	0.001
C22.9 Liver, unspecified	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
T79.8 Other early complications of trauma	0.000	0.999	0.001
Y40.6 Rifamycins	0.001	0.999	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.999	0.001
N83.0 Follicular cyst of ovary	0.001	0.999	0.000
S63.1 Dislocation finger	0.000	0.999	0.001
S63.2 Multiple dislocations of fingers	0.000	0.999	0.001
Z01.5 Diagnostic skin and sensitisation tests	0.001	0.999	0.000
C67 Malignant neoplasm of bladder	0.001	0.999	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.999	0.001
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.999	0.001
Z89 Acquired absence of limb	0.001	0.999	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.999	0.001
G03.9 Meningitis, unspecified	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.001	0.999	0.000
Y44.5 Thrombolytic drugs	0.001	0.999	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.000	0.999	0.001
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.999	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.001	0.999	0.000
F45.9 Somatoform disorder, unspecified	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.999	0.001
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.999	0.001
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.999	0.001
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.001	0.999	0.000
U80.1 Methicillin resistant agent	0.001	0.999	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.999	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.999	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.999	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.999	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.999	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.999	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.999	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.999	0.000
C22.7 Other specified carcinomas of liver	0.001	0.999	0.000
C22.4 Other sarcomas of liver	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations