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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45509595
log Bayes Factor = 186.765
Chromosome 6   position 27,840,926  (GRCh37) Explore rs45509595 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.972 0.000 0.028
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
K40 Inguinal hernia
0.000 0.001 0.999
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.971 0.001 0.028
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
K44 Diaphragmatic hernia
0.000 0.002 0.998
M15-M19 Arthrosis
0.998 0.002 0.000
M17 Gonarthrosis [arthrosis of knee]
0.998 0.002 0.000
K40-K46 Hernia
0.001 0.002 0.997
K90 Intestinal malabsorption
0.993 0.004 0.003
E83.1 Disorders of iron metabolism
0.000 0.005 0.995
M17.9 Gonarthrosis, unspecified
0.994 0.006 0.000
N40-N51 Diseases of male genital organs
0.000 0.006 0.994
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
D80-D89 Certain disorders involving the immune mechanism
0.993 0.007 0.000
E20-E35 Disorders of other endocrine glands
0.991 0.009 0.000
H30-H36 Disorders of choroid and retina
0.991 0.009 0.000
L20-L30 Dermatitis and eczema
0.990 0.010 0.000
M23 Internal derangement of knee
0.989 0.011 0.000
E27 Other disorders of adrenal gland
0.989 0.011 0.000
E27.1 Primary adrenocortical insufficiency
0.986 0.014 0.000
N42 Other disorders of prostate
0.000 0.015 0.985
E11 Non-insulin-dependent diabetes mellitus
0.984 0.016 0.000
D86 Sarcoidosis
0.984 0.016 0.000
E10.3 With ophthalmic complications
0.983 0.017 0.000
M20.1 Hallux valgus (acquired)
0.000 0.018 0.982
M20 Acquired deformities of fingers and toes
0.000 0.020 0.980
K70-K77 Diseases of liver
0.977 0.021 0.002
M20.5 Other deformities of toe(s) (acquired)
0.000 0.021 0.979
H43-H45 Disorders of vitreous body and globe
0.978 0.022 0.000
L30 Other dermatitis
0.978 0.022 0.000
K75 Other inflammatory liver diseases
0.977 0.022 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.976 0.024 0.000
K75.4 Autoimmune hepatitis
0.974 0.026 0.000
D86.9 Sarcoidosis, unspecified
0.973 0.027 0.000
E14 Unspecified diabetes mellitus
0.966 0.034 0.000
L30.9 Dermatitis, unspecified
0.966 0.034 0.000
L50-L54 Urticaria and erythema
0.965 0.035 0.000
H36 Retinal disorders in diseases classified elsewhere
0.964 0.036 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.039 0.961
E10.1 With ketoacidosis
0.960 0.040 0.000
H43 Disorders of vitreous body
0.959 0.041 0.000
N30-N39 Other diseases of urinary system
0.000 0.043 0.957
Chapter XIV Diseases of the genitourinary system
0.000 0.044 0.956
M34 Systemic sclerosis
0.954 0.046 0.000
M06 Other rheumatoid arthritis
0.949 0.051 0.000
E10.2 With renal complications
0.948 0.052 0.000
N39 Other disorders of urinary system
0.000 0.053 0.947
H43.1 Vitreous haemorrhage
0.946 0.054 0.000
H02 Other disorders of eyelid
0.946 0.054 0.000
H36.0 Diabetic retinopathy
0.944 0.056 0.000
E11.9 Without complications
0.942 0.058 0.000
E11.5 With peripheral circulatory complications
0.942 0.058 0.000
N42.8 Other specified disorders of prostate
0.000 0.059 0.941
M31 Other necrotising vasculopathies
0.941 0.059 0.000
M23.3 Other meniscus derangements
0.940 0.060 0.000
N32 Other disorders of bladder
0.000 0.066 0.934
N32.0 Bladder-neck obstruction
0.000 0.070 0.930
M06.9 Rheumatoid arthritis, unspecified
0.930 0.070 0.000
H34 Retinal vascular occlusions
0.928 0.072 0.000
M22 Disorders of patella
0.927 0.073 0.000
M17.1 Other primary gonarthrosis
0.927 0.073 0.000
N39.8 Other specified disorders of urinary system
0.000 0.073 0.927
M65-M68 Disorders of synovium and tendon
0.926 0.074 0.000
M17.0 Primary gonarthrosis, bilateral
0.926 0.074 0.000
H02.5 Other disorders affecting eyelid function
0.924 0.076 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.920 0.080 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.081 0.919
E14.3 With ophthalmic complications
0.917 0.083 0.000
K35-K38 Diseases of appendix
0.904 0.083 0.013
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.914 0.086 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.089 0.911
K73 Chronic hepatitis, not elsewhere classified
0.908 0.091 0.001
M60-M63 Disorders of muscles
0.909 0.091 0.000
M70-M79 Other soft tissue disorders
0.909 0.091 0.000
L27 Dermatitis due to substances taken internally
0.907 0.093 0.000
Chapter XX External causes of morbidity and mortality
0.906 0.094 0.000
K72 Hepatic failure, not elsewhere classified
0.905 0.094 0.001
L80-L99 Other disorders of the skin and subcutaneous tissue
0.900 0.100 0.000
E11.3 With ophthalmic complications
0.898 0.102 0.000
M72 Fibroblastic disorders
0.897 0.103 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.897 0.103 0.000
M67 Other disorders of synovium and tendon
0.897 0.103 0.000
K75.8 Other specified inflammatory liver diseases
0.895 0.105 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.895 0.105 0.000
K35 Acute appendicitis
0.890 0.110 0.001
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.890 0.110 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.890 0.110 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.000 0.110 0.890
M11 Other crystal arthropathies
0.889 0.111 0.000
M24 Other specific joint derangements
0.889 0.111 0.000
M31.6 Other giant cell arteritis
0.887 0.113 0.000
N81 Female genital prolapse
0.000 0.113 0.887
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.886 0.114 0.000
H02.1 Ectropion of eyelid
0.885 0.115 0.000
N81.2 Incomplete uterovaginal prolapse
0.000 0.116 0.884
L52 Erythema nodosum
0.883 0.117 0.000
N87 Dysplasia of cervix uteri
0.000 0.120 0.880
K35.9 Acute appendicitis, unspecified
0.879 0.121 0.000
M07 Psoriatic and enteropathic arthropathies
0.877 0.123 0.000
N41 Inflammatory diseases of prostate
0.000 0.124 0.876
E70-E90 Metabolic disorders
0.872 0.127 0.000
K75.9 Inflammatory liver disease, unspecified
0.872 0.128 0.000
H34.8 Other retinal vascular occlusions
0.871 0.129 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.870 0.130 0.000
M67.8 Other specified disorders of synovium and tendon
0.870 0.130 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.865 0.135 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.864 0.136 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.862 0.138 0.000
Chapter IX Diseases of the circulatory system
0.859 0.141 0.000
M23.9 Internal derangement of knee, unspecified
0.859 0.141 0.000
I73 Other peripheral vascular diseases
0.859 0.141 0.000
V20-V29 Motorcycle rider injured in transport accident
0.859 0.141 0.000
L50 Urticaria
0.856 0.144 0.000
N34 Urethritis and urethral syndrome
0.000 0.147 0.853
L97 Ulcer of lower limb, not elsewhere classified
0.853 0.147 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.852 0.148 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.851 0.149 0.000
H25-H28 Disorders of lens
0.851 0.149 0.000
L40-L45 Papulosquamous disorders
0.850 0.150 0.000
M10 Gout
0.849 0.151 0.000
M34.1 CR(E)ST syndrome
0.848 0.152 0.000
M25 Other joint disorders, not elsewhere classified
0.848 0.152 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.154 0.846
M35.3 Polymyalgia rheumatica
0.846 0.154 0.000
L10-L14 Bullous disorders
0.845 0.155 0.000
H02.0 Entropion and trichiasis of eyelid
0.842 0.158 0.000
I73.9 Peripheral vascular disease, unspecified
0.842 0.158 0.000
D55-D59 Haemolytic anaemias
0.842 0.158 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.841 0.159 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.000 0.159 0.841
L94 Other localised connective tissue disorders
0.841 0.159 0.000
N81.4 Uterovaginal prolapse, unspecified
0.000 0.159 0.841
K73.2 Chronic active hepatitis, not elsewhere classified
0.838 0.162 0.000
M62 Other disorders of muscle
0.838 0.162 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.838 0.162 0.000
K90.9 Intestinal malabsorption, unspecified
0.835 0.164 0.001
M18 Arthrosis of first carpometacarpal joint
0.836 0.164 0.000
M34.9 Systemic sclerosis, unspecified
0.835 0.165 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.835 0.165 0.000
N36 Other disorders of urethra
0.000 0.169 0.831
N97 Female infertility
0.000 0.169 0.831
N39.9 Disorder of urinary system, unspecified
0.000 0.170 0.830
M23.2 Derangement of meniscus due to old tear or injury
0.828 0.172 0.000
N87.0 Mild cervical dysplasia
0.000 0.173 0.827
M23.6 Other spontaneous disruption of ligament(s) of knee
0.827 0.173 0.000
M86-M90 Other osteopathies
0.827 0.173 0.000
Q50-Q56 Congenital malformations of genital organs
0.826 0.174 0.000
E10.4 With neurological complications
0.825 0.175 0.000
E23 Hypofunction and other disorders of pituitary gland
0.825 0.175 0.000
N39.3 Stress incontinence
0.000 0.177 0.823
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.821 0.179 0.000
M22.3 Other derangements of patella
0.820 0.180 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.819 0.181 0.000
D50-D53 Nutritional anaemias
0.814 0.186 0.000
M11.2 Other chondrocalcinosis
0.814 0.186 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.814 0.186 0.000
N20-N23 Urolithiasis
0.000 0.189 0.811
H05 Disorders of orbit
0.810 0.190 0.000
K72.0 Acute and subacute hepatic failure
0.810 0.190 0.000
I77 Other disorders of arteries and arterioles
0.810 0.190 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.193 0.807
E20 Hypoparathyroidism
0.806 0.194 0.000
E10.5 With peripheral circulatory complications
0.804 0.196 0.000
E14.9 Without complications
0.804 0.196 0.000
D83 Common variable immunodeficiency
0.804 0.196 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.802 0.198 0.000
L28 Lichen simplex chronicus and prurigo
0.801 0.199 0.000
H02.6 Xanthelasma of eyelid
0.800 0.200 0.000
E50-E64 Other nutritional deficiencies
0.799 0.201 0.000
H01 Other inflammation of eyelid
0.798 0.202 0.000
N48 Other disorders of penis
0.000 0.203 0.797
H26 Other cataract
0.797 0.203 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.795 0.205 0.000
E78.5 Hyperlipidaemia, unspecified
0.794 0.206 0.000
M07.3 Other psoriatic arthropathies
0.794 0.206 0.000
L43 Lichen planus
0.792 0.207 0.000
X20-X29 Contact with venomous animals and plants
0.792 0.208 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.000 0.208 0.792
N42.9 Disorder of prostate, unspecified
0.000 0.209 0.791
L27.0 Generalised skin eruption due to drugs and medicaments
0.788 0.212 0.000
M15 Polyarthrosis
0.788 0.212 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.786 0.214 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.784 0.214 0.002
E13 Other specified diabetes mellitus
0.786 0.214 0.000
H26.9 Cataract, unspecified
0.784 0.216 0.000
N20 Calculus of kidney and ureter
0.000 0.216 0.784
D86.8 Sarcoidosis of other and combined sites
0.784 0.216 0.000
M62.8 Other specified disorders of muscle
0.783 0.217 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.783 0.217 0.000
M35.7 Hypermobility syndrome
0.783 0.217 0.000
E07 Other disorders of thyroid
0.783 0.217 0.000
M25.9 Joint disorder, unspecified
0.782 0.218 0.000
V23.4 Driver injured in traffic accident
0.782 0.218 0.000
W00-W19 Falls
0.782 0.218 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.781 0.219 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.779 0.221 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.779 0.221 0.000
W20-W49 Exposure to inanimate mechanical forces
0.776 0.224 0.000
E10.8 With unspecified complications
0.775 0.225 0.000
H30 Chorioretinal inflammation
0.774 0.225 0.000
L30.8 Other specified dermatitis
0.774 0.226 0.000
N85.2 Hypertrophy of uterus
0.000 0.227 0.773
I77.6 Arteritis, unspecified
0.772 0.228 0.000
K46 Unspecified abdominal hernia
0.000 0.228 0.771
N20.0 Calculus of kidney
0.000 0.229 0.771
L27.1 Localised skin eruption due to drugs and medicaments
0.770 0.230 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.769 0.231 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.769 0.231 0.000
N46 Male infertility
0.000 0.231 0.769
K72.9 Hepatic failure, unspecified
0.767 0.233 0.000
M86 Osteomyelitis
0.767 0.233 0.000
E78.6 Lipoprotein deficiency
0.766 0.234 0.000
E10.0 With coma
0.766 0.234 0.000
M22.2 Patellofemoral disorders
0.766 0.234 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.766 0.234 0.000
E24 Cushing's syndrome
0.765 0.235 0.000
N34.2 Other urethritis
0.000 0.235 0.765
M76 Enthesopathies of lower limb, excluding foot
0.765 0.235 0.000
H34.2 Other retinal artery occlusions
0.764 0.236 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.763 0.237 0.000
H31 Other disorders of choroid
0.762 0.238 0.000
D80 Immunodeficiency with predominantly antibody defects
0.762 0.238 0.000
E16.1 Other hypoglycaemia
0.762 0.238 0.000
N84 Polyp of female genital tract
0.000 0.238 0.762
M34.8 Other forms of systemic sclerosis
0.761 0.239 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.761 0.239 0.000
L53 Other erythematous conditions
0.760 0.240 0.000
M32 Systemic lupus erythematosus
0.759 0.241 0.000
N97.9 Female infertility, unspecified
0.000 0.241 0.759
H02.3 Blepharochalasis
0.758 0.242 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.755 0.245 0.000
N41.0 Acute prostatitis
0.000 0.245 0.755
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.754 0.246 0.000
D61 Other aplastic anaemias
0.752 0.248 0.000
H43.8 Other disorders of vitreous body
0.751 0.249 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.749 0.250 0.000
N42.2 Atrophy of prostate
0.000 0.252 0.748
H44 Disorders of globe
0.748 0.252 0.000
D62 Acute posthaemorrhagic anaemia
0.747 0.253 0.000
M00-M03 Infectious arthropathies
0.747 0.253 0.000
M12 Other specific arthropathies
0.746 0.254 0.000
N48.1 Balanoposthitis
0.000 0.254 0.746
L43.9 Lichen planus, unspecified
0.746 0.254 0.000
M22.8 Other disorders of patella
0.745 0.254 0.000
L89 Decubitus ulcer
0.745 0.255 0.000
M06.4 Inflammatory polyarthropathy
0.744 0.256 0.000
I73.0 Raynaud's syndrome
0.742 0.258 0.000
E78.1 Pure hyperglyceridaemia
0.742 0.258 0.000
L93 Lupus erythematosus
0.741 0.259 0.000
E14.1 With ketoacidosis
0.741 0.259 0.000
W75-W84 Other accidental threats to breathing
0.741 0.259 0.000
N84.1 Polyp of cervix uteri
0.000 0.261 0.739
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.262 0.738
N81.3 Complete uterovaginal prolapse
0.000 0.262 0.738
M23.4 Loose body in knee
0.738 0.262 0.000
M10.0 Idiopathic gout
0.738 0.262 0.000
E11.1 With ketoacidosis
0.738 0.262 0.000
S40-S49 Injuries to the shoulder and upper arm
0.737 0.263 0.000
M23.1 Discoid meniscus (congenital)
0.737 0.263 0.000
E29 Testicular dysfunction
0.737 0.263 0.000
I74 Arterial embolism and thrombosis
0.737 0.263 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.736 0.264 0.000
H46 Optic neuritis
0.736 0.264 0.000
L92.0 Granuloma annulare
0.736 0.264 0.000
N36.2 Urethral caruncle
0.000 0.265 0.735
D86.3 Sarcoidosis of skin
0.734 0.266 0.000
D59 Acquired haemolytic anaemia
0.734 0.266 0.000
L23 Allergic contact dermatitis
0.733 0.266 0.000
E10.6 With other specified complications
0.732 0.268 0.000
M25.7 Osteophyte
0.732 0.268 0.000
D86.0 Sarcoidosis of lung
0.732 0.268 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.732 0.268 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.268 0.731
D84 Other immunodeficiencies
0.731 0.269 0.000
H43.9 Disorder of vitreous body, unspecified
0.731 0.269 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.729 0.271 0.000
K73.9 Chronic hepatitis, unspecified
0.728 0.272 0.000
M23.0 Cystic meniscus
0.728 0.272 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.272 0.728
N41.1 Chronic prostatitis
0.000 0.273 0.727
M67.4 Ganglion
0.726 0.274 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.726 0.274 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.725 0.275 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.724 0.276 0.000
E27.2 Addisonian crisis
0.723 0.277 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.723 0.277 0.000
L94.0 Localised scleroderma [morphea]
0.723 0.277 0.000
W50-W64 Exposure to animate mechanical forces
0.722 0.278 0.000
E11.0 With coma
0.720 0.280 0.000
H47.2 Optic atrophy
0.720 0.280 0.000
E78.4 Other hyperlipidaemia
0.718 0.282 0.000
H35 Other retinal disorders
0.718 0.282 0.000
M17.3 Other posttraumatic gonarthrosis
0.718 0.282 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.718 0.282 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
M35.2 Behcet's disease
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.283 0.716
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.283 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.696 0.284 0.020
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.284 0.715
E03.8 Other specified hypothyroidism
0.716 0.284 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.716 0.284 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.715 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.715 0.284 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.714 0.286 0.000
K90.8 Other intestinal malabsorption
0.712 0.286 0.002
K90.3 Pancreatic steatorrhoea
0.712 0.286 0.002
K90.2 Blind loop syndrome, not elsewhere classified
0.712 0.286 0.002
K90.1 Tropical sprue
0.712 0.286 0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.714 0.286 0.000
L50.0 Allergic urticaria
0.713 0.287 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.713 0.287 0.000
M24.1 Other articular cartilage disorders
0.713 0.287 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.287 0.713
N44 Torsion of testis
0.000 0.287 0.713
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.287 0.000
M08 Juvenile arthritis
0.712 0.287 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.712 0.288 0.000
D82 Immunodeficiency associated with other major defects
0.712 0.288 0.000
D81 Combined immunodeficiencies
0.712 0.288 0.000
H53-H54 Visual disturbances and blindness
0.711 0.289 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.711 0.289 0.000
E32 Diseases of thymus
0.711 0.289 0.000
E31 Polyglandular dysfunction
0.711 0.289 0.000
E30 Disorders of puberty, not elsewhere classified
0.711 0.289 0.000
E25 Adrenogenital disorders
0.711 0.289 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.711 0.289 0.000
X23 Contact with hornets, wasps and bees
0.711 0.289 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.710 0.289 0.000
L25 Unspecified contact dermatitis
0.710 0.290 0.000
L24 Irritant contact dermatitis
0.710 0.290 0.000
L26 Exfoliative dermatitis
0.710 0.290 0.000
L22 Diaper [napkin] dermatitis
0.710 0.290 0.000
D86.1 Sarcoidosis of lymph nodes
0.709 0.291 0.000
O60-O75 Complications of labour and delivery
0.709 0.291 0.000
E27.5 Adrenomedullary hyperfunction
0.709 0.291 0.000
E27.0 Other adrenocortical overactivity
0.709 0.291 0.000
E11.6 With other specified complications
0.708 0.291 0.000
L20 Atopic dermatitis
0.708 0.292 0.000
M86.9 Osteomyelitis, unspecified
0.707 0.293 0.000
N42.3 Dysplasia of prostate
0.000 0.294 0.706
M33 Dermatopolymyositis
0.706 0.294 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.294 0.000
E11.7 With multiple complications
0.706 0.294 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.705 0.294 0.000
W22 Striking against or struck by other objects
0.705 0.295 0.000
L13 Other bullous disorders
0.704 0.296 0.000
L51 Erythema multiforme
0.704 0.296 0.000
N32.8 Other specified disorders of bladder
0.000 0.296 0.704
L50.9 Urticaria, unspecified
0.703 0.297 0.000
N87.1 Moderate cervical dysplasia
0.000 0.297 0.703
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.703 0.297 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.702 0.298 0.000
K77 Liver disorders in diseases classified elsewhere
0.700 0.298 0.001
K71 Toxic liver disease
0.700 0.298 0.001
H47.3 Other disorders of optic disk
0.702 0.298 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.702 0.298 0.000
I70 Atherosclerosis
0.701 0.298 0.000
H43.2 Crystalline deposits in vitreous body
0.701 0.299 0.000
S20-S29 Injuries to the thorax
0.701 0.299 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.701 0.299 0.000
L30.5 Pityriasis alba
0.701 0.299 0.000
L30.4 Erythema intertrigo
0.701 0.299 0.000
L30.3 Infective dermatitis
0.701 0.299 0.000
L30.2 Cutaneous autosensitisation
0.701 0.299 0.000
L30.1 Dyshidrosis [pompholyx]
0.701 0.299 0.000
L30.0 Nummular dermatitis
0.701 0.299 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.701 0.299 0.000
K75.2 Nonspecific reactive hepatitis
0.701 0.299 0.000
K75.1 Phlebitis of portal vein
0.701 0.299 0.000
L80 Vitiligo
0.699 0.301 0.000
M13 Other arthritis
0.699 0.301 0.000
M14 Arthropathies in other diseases classified elsewhere
0.698 0.302 0.000
M35.1 Other overlap syndromes
0.698 0.302 0.000
M30 Polyarteritis nodosa and related conditions
0.698 0.302 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.698 0.302 0.000
Q53 Undescended testicle
0.698 0.302 0.000
O73 Retained placenta and membranes, without haemorrhage
0.698 0.302 0.000
O62 Abnormalities of forces of labour
0.697 0.303 0.000
E06 Thyroiditis
0.696 0.304 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.695 0.305 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.695 0.305 0.000
N42.0 Calculus of prostate
0.000 0.306 0.694
E23.2 Diabetes insipidus
0.694 0.306 0.000
E14.8 With unspecified complications
0.693 0.307 0.000
E14.7 With multiple complications
0.693 0.307 0.000
E14.6 With other specified complications
0.693 0.307 0.000
E14.5 With peripheral circulatory complications
0.693 0.307 0.000
E14.4 With neurological complications
0.693 0.307 0.000
E14.2 Withrenal complications
0.693 0.307 0.000
E14.0 With coma
0.693 0.307 0.000
N97.1 Female infertility of tubal origin
0.000 0.307 0.693
L54 Erythema in diseases classified elsewhere
0.692 0.308 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.692 0.308 0.000
E05.8 Other thyrotoxicosis
0.692 0.308 0.000
N36.3 Prolapsed urethral mucosa
0.000 0.308 0.692
H36.8 Other retinal disorders in diseases classified elsewhere
0.691 0.309 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.310 0.690
N89 Other noninflammatory disorders of vagina
0.000 0.310 0.690
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.690 0.310 0.000
H01.0 Blepharitis
0.689 0.311 0.000
D50 Iron deficiency anaemia
0.689 0.311 0.000
S00-S09 Injuries to the head
0.689 0.311 0.000
O73.0 Retained placenta, without haemorrhage
0.688 0.312 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.688 0.312 0.000
H43.0 Vitreous prolapse
0.687 0.312 0.000
M24.2 Disorder of ligament
0.687 0.313 0.000
M23.8 Other internal derangements of knee
0.687 0.313 0.000
N20.1 Calculus of ureter
0.000 0.313 0.687
N48.4 Impotence of organic origin
0.000 0.314 0.686
N37 Urethral disorders in diseases classified elsewhere
0.000 0.314 0.686
N33 Bladder disorders in diseases classified elsewhere
0.000 0.314 0.686
M34.2 Systemic sclerosis induced by drugs and chemicals
0.684 0.316 0.000
M34.0 Progressive systemic sclerosis
0.684 0.316 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.683 0.317 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.682 0.317 0.001
X00-X09 Exposure to smoke, fire and flames
0.682 0.318 0.000
E84 Cystic fibrosis
0.681 0.319 0.000
N81.9 Female genital prolapse, unspecified
0.000 0.319 0.681
M06.8 Other specified rheumatoid arthritis
0.681 0.319 0.000
M06.2 Rheumatoid bursitis
0.681 0.319 0.000
M06.1 Adult-onset Still's disease
0.681 0.319 0.000
O62.2 Other uterine inertia
0.680 0.320 0.000
N91 Absent, scanty and rare menstruation
0.000 0.321 0.679
Q43 Other congenital malformations of intestine
0.679 0.321 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.321 0.679
H02.7 Other degenerative disorders of eyelid and periocular area
0.678 0.322 0.000
L94.9 Localised connective tissue disorder, unspecified
0.678 0.322 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.677 0.323 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.677 0.323 0.000
H27 Other disorders of lens
0.677 0.323 0.000
E40-E46 Malnutrition
0.677 0.323 0.000
K36 Other appendicitis
0.668 0.324 0.008
H35.8 Other specified retinal disorders
0.675 0.325 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.675 0.325 0.000
Q39 Congenital malformations of oesophagus
0.675 0.325 0.000
M31.9 Necrotising vasculopathy, unspecified
0.674 0.326 0.000
M31.8 Other specified necrotising vasculopathies
0.674 0.326 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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