TreeWAS – Variant ID: rs4558075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E27.4 Other and unspecified adrenocortical insufficiency	0.022	0.978	0.000
E27 Other disorders of adrenal gland	0.020	0.980	0.000
E27.1 Primary adrenocortical insufficiency	0.019	0.981	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.016	0.984	0.000
E27.8 Other specified disorders of adrenal gland	0.015	0.985	0.000
E27.5 Adrenomedullary hyperfunction	0.014	0.986	0.000
E27.0 Other adrenocortical overactivity	0.014	0.986	0.000
E27.2 Addisonian crisis	0.014	0.986	0.000
E27.9 Disorder of adrenal gland, unspecified	0.013	0.987	0.000
E20-E35 Disorders of other endocrine glands	0.013	0.987	0.000
E03.9 Hypothyroidism, unspecified	0.012	0.988	0.000
E34 Other endocrine disorders	0.012	0.988	0.000
E34.9 Endocrine disorder, unspecified	0.011	0.989	0.000
E26 Hyperaldosteronism	0.011	0.989	0.000
Z01.6 Radiological examination, not elsewhere classified	0.000	0.989	0.011
E29 Testicular dysfunction	0.011	0.989	0.000
E20 Hypoparathyroidism	0.010	0.990	0.000
E32 Diseases of thymus	0.010	0.990	0.000
I34.0 Mitral (valve) insufficiency	0.010	0.990	0.000
E31 Polyglandular dysfunction	0.010	0.990	0.000
E25 Adrenogenital disorders	0.010	0.990	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.010	0.990	0.000
E30 Disorders of puberty, not elsewhere classified	0.010	0.990	0.000
E28 Ovarian dysfunction	0.010	0.990	0.000
E23 Hypofunction and other disorders of pituitary gland	0.010	0.990	0.000
E34.8 Other specified endocrine disorders	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
E26.0 Primary hyperaldosteronism	0.009	0.991	0.000
E29.1 Testicular hypofunction	0.009	0.991	0.000
E26.9 Hyperaldosteronism, unspecified	0.009	0.991	0.000
E34.5 Androgen resistance syndrome	0.009	0.991	0.000
E34.4 Constitutional tall stature	0.009	0.991	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.009	0.991	0.000
E34.1 Other hypersecretion of intestinal hormones	0.009	0.991	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.009	0.991	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
E34.0 Carcinoid syndrome	0.008	0.991	0.000
E20.9 Hypoparathyroidism, unspecified	0.008	0.992	0.000
E23.2 Diabetes insipidus	0.008	0.992	0.000
E26.8 Other hyperaldosteronism	0.008	0.992	0.000
E26.1 Secondary hyperaldosteronism	0.008	0.992	0.000
E34.3 Short stature, not elsewhere classified	0.008	0.992	0.000
I34 Nonrheumatic mitral valve disorders	0.008	0.992	0.000
E32.9 Disease of thymus, unspecified	0.008	0.992	0.000
E32.8 Other diseases of thymus	0.008	0.992	0.000
E29.9 Testicular dysfunction, unspecified	0.008	0.992	0.000
E29.8 Other testicular dysfunction	0.008	0.992	0.000
E29.0 Testicular hyperfunction	0.008	0.992	0.000
I34.1 Mitral (valve) prolapse	0.008	0.992	0.000
E20.8 Other hypoparathyroidism	0.008	0.992	0.000
E20.1 Pseudohypoparathyroidism	0.008	0.992	0.000
E20.0 Idiopathic hypoparathyroidism	0.008	0.992	0.000
E32.1 Abscess of thymus	0.008	0.992	0.000
E32.0 Persistent hyperplasia of thymus	0.008	0.992	0.000
E28.3 Primary ovarian failure	0.008	0.992	0.000
R73.9 Hyperglycaemia, unspecified	0.008	0.992	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.007	0.992	0.000
E31.0 Autoimmune polyglandular failure	0.007	0.993	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.007	0.993	0.000
E31.9 Polyglandular dysfunction, unspecified	0.007	0.993	0.000
E31.8 Other polyglandular dysfunction	0.007	0.993	0.000
E31.1 Polyglandular hyperfunction	0.007	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.007	0.993	0.000
E25.8 Other adrenogenital disorders	0.007	0.993	0.000
E30.9 Disorder of puberty, unspecified	0.007	0.993	0.000
E30.8 Other disorders of puberty	0.007	0.993	0.000
E30.1 Precocious puberty	0.007	0.993	0.000
E30.0 Delayed puberty	0.007	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.007	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.007	0.993	0.000
E28.9 Ovarian dysfunction, unspecified	0.007	0.993	0.000
E28.8 Other ovarian dysfunction	0.007	0.993	0.000
E28.1 Androgen excess	0.007	0.993	0.000
E28.0 Oestrogen excess	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.007	0.993	0.000
E22.0 Acromegaly and pituitary gigantism	0.007	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.007	0.993	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
E22.8 Other hyperfunction of pituitary gland	0.007	0.993	0.000
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
E24 Cushing's syndrome	0.007	0.993	0.000
L29.0 Pruritus ani	0.000	0.993	0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.993	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.006	0.994	0.000
E21.2 Other hyperparathyroidism	0.006	0.994	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.006	0.994	0.000
M87.9 Osteonecrosis, unspecified	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.006	0.994	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.994	0.006
E22.1 Hyperprolactinaemia	0.006	0.994	0.000
E14.3 With ophthalmic complications	0.006	0.994	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.994	0.006
E23.0 Hypopituitarism	0.006	0.994	0.000
R73 Elevated blood glucose level	0.006	0.994	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.005	0.995	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.995	0.005
Z01.9 Special examination, unspecified	0.000	0.995	0.005
M43.16 Spondylolisthesis (Lumbar region)	0.005	0.995	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.005	0.995	0.000
E03 Other hypothyroidism	0.005	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.005	0.995	0.000
E24.3 Ectopic ACTH syndrome	0.005	0.995	0.000
E24.1 Nelson's syndrome	0.005	0.995	0.000
Z01.2 Dental examination	0.000	0.995	0.005
E24.8 Other Cushing's syndrome	0.005	0.995	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.995	0.005
S06.2 Diffuse brain injury	0.000	0.995	0.005
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
N30.2 Other chronic cystitis	0.000	0.995	0.005
E24.2 Drug-induced Cushing's syndrome	0.005	0.995	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.005	0.995	0.000
L82 Seborrhoeic keratosis	0.000	0.995	0.005
Z01.4 Gynaecological examination (general)(routine)	0.000	0.995	0.005
Z01.3 Examination of blood pressure	0.000	0.995	0.005
Z01.0 Examination of eyes and vision	0.000	0.995	0.005
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.004	0.995	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.004	0.995	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.004	0.995	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.004	0.995	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.004	0.995	0.000
R71 Abnormality of red blood cells	0.005	0.995	0.000
Z01.1 Examination of ears and hearing	0.000	0.995	0.004
E24.0 Pituitary-dependent Cushing's disease	0.004	0.995	0.000
S06.4 Epidural haemorrhage	0.000	0.995	0.005
M87.96 Osteonecrosis, unspecified (Lower leg)	0.004	0.995	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.004	0.996	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.996	0.004
S06 Intracranial injury	0.000	0.996	0.004
Z47.8 Other specified orthopaedic follow-up care	0.004	0.996	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.004	0.996	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.004	0.996	0.000
S06.3 Focal brain injury	0.000	0.996	0.004
S06.5 Traumatic subdural haemorrhage	0.000	0.996	0.004
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.996	0.004
R76 Other abnormal immunological findings in serum	0.004	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
E03.5 Myxoedema coma	0.004	0.996	0.000
E03.4 Atrophy of thyroid (acquired)	0.004	0.996	0.000
E03.3 Postinfectious hypothyroidism	0.004	0.996	0.000
M43.1 Spondylolisthesis	0.004	0.996	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.004	0.996	0.000
R79 Other abnormal findings of blood chemistry	0.004	0.996	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.004	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.004	0.996	0.000
R76.0 Raised antibody titer	0.004	0.996	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.004	0.996	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.996	0.004
R79.0 Abnormal level of blood mineral	0.004	0.996	0.000
M86.9 Osteomyelitis, unspecified	0.004	0.996	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.996	0.004
M87 Osteonecrosis	0.004	0.996	0.000
R73.0 Abnormal glucose tolerance test	0.004	0.996	0.000
Z01.8 Other specified special examinations	0.000	0.996	0.004
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.996	0.003
R79.9 Abnormal finding of blood chemistry, unspecified	0.004	0.996	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.003	0.996	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.003	0.996	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.003	0.996	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
M43.10 Spondylolisthesis (Multiple sites in spine)	0.003	0.997	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.000	0.997	0.003
S06.0 Concussion	0.000	0.997	0.003
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.000	0.997	0.003
R76.9 Abnormal immunological finding in serum, unspecified	0.003	0.997	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
E03.1 Congenital hypothyroidism without goitre	0.003	0.997	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.003	0.997	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.997	0.003
E03.8 Other specified hypothyroidism	0.003	0.997	0.000
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.003	0.997	0.000
E05.9 Thyrotoxicosis, unspecified	0.003	0.997	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
Z01.7 Laboratory examination	0.000	0.997	0.003
R76.2 False-positive serological test for syphilis	0.003	0.997	0.000
R76.1 Abnormal reaction to tuberculin test	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.997	0.003
S06.8 Other intracranial injuries	0.000	0.997	0.003
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.997	0.003
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.003	0.997	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.003	0.997	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.003	0.997	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M86 Osteomyelitis	0.003	0.997	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.997	0.003
R77 Other abnormalities of plasma proteins	0.003	0.997	0.000
M87.1 Osteonecrosis due to drugs	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
B37.9 Candidiasis, unspecified	0.003	0.997	0.000
C71.9 Brain, unspecified	0.003	0.997	0.000
M87.3 Other secondary osteonecrosis	0.003	0.997	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
Q27.3 Peripheral arteriovenous malformation	0.000	0.997	0.003
S06.9 Intracranial injury, unspecified	0.000	0.997	0.003
M86.93 Osteomyelitis, unspecified (Forearm)	0.003	0.997	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.003	0.997	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.003	0.997	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.003	0.997	0.000
R76.8 Other specified abnormal immunological findings in serum	0.003	0.997	0.000
O03.4 Incomplete, without complication	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
E07 Other disorders of thyroid	0.003	0.997	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.003	0.997	0.000
R78.0 Finding of alcohol in blood	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.003
R78.9 Finding of unspecified substance, not normally found in blood	0.003	0.997	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.003	0.997	0.000
R78.6 Finding of steroid agent in blood	0.003	0.997	0.000
R78.5 Finding of psychotropic drug in blood	0.003	0.997	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.003	0.997	0.000
R78.3 Finding of hallucinogen in blood	0.003	0.997	0.000
R78.2 Finding of cocaine in blood	0.003	0.997	0.000
R78.1 Finding of opiate drug in blood	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.000	0.997	0.003
M87.8 Other osteonecrosis	0.003	0.997	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.000	0.997	0.003
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.997	0.003
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.997	0.003
M86-M90 Other osteopathies	0.003	0.997	0.000
I50.9 Heart failure, unspecified	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.997	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.997	0.003
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
M86.8 Other osteomyelitis	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.997	0.003
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.997	0.002
Q25.0 Patent ductus arteriosus	0.000	0.997	0.003
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.997	0.003
Q25 Congenital malformations of great arteries	0.000	0.997	0.003
D51.2 Transcobalamin II deficiency	0.002	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.997	0.000
R77.1 Abnormality of globulin	0.002	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.997	0.003
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
R77.8 Other specified abnormalities of plasma proteins	0.002	0.997	0.000
M88 Paget's disease of bone [osteitis deformans]	0.003	0.997	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.997	0.002
E21.0 Primary hyperparathyroidism	0.002	0.997	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.997	0.003
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.997	0.002
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.997	0.000
E07.8 Other specified disorders of thyroid	0.002	0.997	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.002	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.002	0.997	0.000
M86.2 Subacute osteomyelitis	0.002	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.002	0.997	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.003	0.997	0.000
K14.8 Other diseases of tongue	0.003	0.997	0.000
M43.12 Spondylolisthesis (Cervical region)	0.002	0.997	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.997	0.000
R77.2 Abnormality of alphafetoprotein	0.002	0.997	0.000
E14 Unspecified diabetes mellitus	0.002	0.997	0.000
R70.1 Abnormal plasma viscosity	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.002	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.002	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.002	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.002	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.002	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.002	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.002	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.002	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.002	0.998	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.002	0.998	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.002	0.998	0.000
M86.1 Other acute osteomyelitis	0.002	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.002	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.002	0.998	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.002	0.998	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.002	0.998	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.002	0.998	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.002	0.998	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.002	0.998	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.002	0.998	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.002	0.998	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.38 Other secondary osteonecrosis (Other)	0.002	0.998	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.002	0.998	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.002	0.998	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.002	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
E14.2 Withrenal complications	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
Y86 Sequelae of other accidents	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.000	0.998	0.002
Q27.2 Other congenital malformations of renal artery	0.000	0.998	0.002
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.998	0.002
R77.0 Abnormality of albumin	0.002	0.998	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.002	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.002	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.002	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.998	0.002
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.998	0.002
Q28.1 Other malformations of precerebral vessels	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
M88.8 Paget's disease of other bones	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.000	0.998	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.998	0.002
M86.87 Other osteomyelitis (Ankle and foot)	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.000	0.998	0.002
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
M88.0 Paget's disease of skull	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.000	0.998	0.002
Q21.2 Atrioventricular septal defect	0.000	0.998	0.002
M86.89 Other osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.88 Other osteomyelitis (Other)	0.002	0.998	0.000
M86.84 Other osteomyelitis (Hand)	0.002	0.998	0.000
M86.83 Other osteomyelitis (Forearm)	0.002	0.998	0.000
M86.82 Other osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.000	0.998	0.002
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.998	0.002
R74 Abnormal serum enzyme levels	0.001	0.998	0.001
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
E10.2 With renal complications	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.000	0.998	0.002
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.998	0.002
Q25.8 Other congenital malformations of great arteries	0.000	0.998	0.002
Q25.5 Atresia of pulmonary artery	0.000	0.998	0.002
Q25.2 Atresia of aorta	0.000	0.998	0.002
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.998	0.002
E10-E14 Diabetes mellitus	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.000	0.998	0.002
C71.4 Occipital lobe	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
N18.2 Chronic kidney disease, stage 2	0.002	0.998	0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.002	0.998	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.002	0.998	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.002	0.998	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.28 Subacute osteomyelitis (Other)	0.002	0.998	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.24 Subacute osteomyelitis (Hand)	0.002	0.998	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.002	0.998	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.002	0.998	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.002	0.998	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.002	0.998	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.002	0.998	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.002	0.998	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.002	0.998	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
E14.6 With other specified complications	0.002	0.998	0.000
E14.7 With multiple complications	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.000	0.998	0.002
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.000	0.998	0.002
M86.19 Other acute osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.18 Other acute osteomyelitis (Other)	0.002	0.998	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.14 Other acute osteomyelitis (Hand)	0.002	0.998	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.002	0.998	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.002	0.998	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.002	0.998	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.002	0.998	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.002	0.998	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.002	0.998	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.002	0.998	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.002	0.998	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.002	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.000	0.998	0.002
M79.69 Pain in limb (Site unspecified)	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.002	0.998	0.000
E10.3 With ophthalmic complications	0.002	0.998	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.002	0.998	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.002	0.998	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.002	0.998	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.002	0.998	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.002	0.998	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
R77.9 Abnormality of plasma protein, unspecified	0.002	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.002	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.002	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.002	0.998	0.000
M88.88 Paget's disease of other bones (Other)	0.002	0.998	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
N21.0 Calculus in bladder	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
R17 Unspecified jaundice	0.000	0.998	0.002
M88.00 Paget's disease of skull-Mult sites	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.002	0.998	0.000
K45 Other abdominal hernia	0.002	0.998	0.000
E14.1 With ketoacidosis	0.002	0.998	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations