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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45593035
log Bayes Factor = 0.0204567
Chromosome 2   position 171,671,490  (GRCh37) Explore rs45593035 on Ensembl!
Variant rs45593035 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D69.6 Thrombocytopenia, unspecified
0.081 0.919 0.000
D69 Purpura and other haemorrhagic conditions
0.068 0.932 0.000
D69.5 Secondary thrombocytopenia
0.060 0.940 0.000
D69.0 Allergic purpura
0.055 0.945 0.000
D69.9 Haemorrhagic condition, unspecified
0.049 0.951 0.000
D69.8 Other specified haemorrhagic conditions
0.049 0.951 0.000
D69.4 Other primary thrombocytopenia
0.049 0.951 0.000
D69.2 Other nonthrombocytopenic purpura
0.049 0.951 0.000
D69.1 Qualitative platelet defects
0.049 0.951 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.049 0.951 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.040 0.960 0.000
D66 Hereditary factor VIII deficiency
0.032 0.968 0.000
D67 Hereditary factor IX deficiency
0.029 0.971 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.029 0.971 0.000
D68 Other coagulation defects
0.029 0.971 0.000
D68.9 Coagulation defect, unspecified
0.026 0.974 0.000
D68.0 Von Willebrand's disease
0.021 0.979 0.000
D68.6 Other Thrombophilia
0.021 0.979 0.000
D68.4 Acquired coagulation factor deficiency
0.021 0.979 0.000
D68.1 Hereditary factor XI deficiency
0.021 0.979 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.021 0.979 0.000
D68.8 Other specified coagulation defects
0.020 0.980 0.000
M50.1 Cervical disk disorder with radiculopathy
0.020 0.980 0.000
D68.2 Hereditary deficiency of other clotting factors
0.019 0.981 0.000
M50 Cervical disk disorders
0.018 0.982 0.000
D68.5 Primary Thrombophilia
0.017 0.983 0.000
M54.3 Sciatica
0.017 0.983 0.000
M54.39 Sciatica (Site unspecified)
0.017 0.983 0.000
N50.8 Other specified disorders of male genital organs
0.000 0.984 0.016
M54 Dorsalgia
0.016 0.984 0.000
M54.36 Sciatica (Lumbar region)
0.016 0.984 0.000
M50-M54 Other dorsopathies
0.016 0.984 0.000
M54.37 Sciatica (Lumbosacral region)
0.015 0.985 0.000
M50.3 Other cervical disk degeneration
0.015 0.985 0.000
M54.5 Low back pain
0.014 0.986 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.014 0.986 0.000
M54.59 Low back pain (Site unspecified)
0.014 0.986 0.000
M54.57 Low back pain (Lumbosacral region)
0.013 0.987 0.000
M54.8 Other dorsalgia
0.013 0.987 0.000
M50.9 Cervical disk disorder, unspecified
0.013 0.987 0.000
M50.8 Other cervical disk disorders
0.013 0.987 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.013 0.987 0.000
M54.35 Sciatica (Thoracolumbar region)
0.013 0.987 0.000
M54.34 Sciatica-Thoracic
0.013 0.987 0.000
M54.33 Sciatica-Cervicothoracic
0.013 0.987 0.000
M54.32 Sciatica-Cervical
0.013 0.987 0.000
M54.31 Sciatica-Occipit-atl-axl
0.013 0.987 0.000
M54.30 Sciatica (Multiple sites in spine)
0.013 0.987 0.000
M50.0 Cervical disk disorder with myelopathy
0.013 0.987 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.012 0.988 0.000
M35.3 Polymyalgia rheumatica
0.012 0.988 0.000
M50.2 Other cervical disk displacement
0.012 0.988 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.012 0.988 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.012 0.988 0.000
O16 Unspecified maternal hypertension
0.012 0.988 0.000
M54.0 Panniculitis affecting regions of neck and back
0.012 0.988 0.000
D73 Diseases of spleen
0.012 0.988 0.000
M35 Other systemic involvement of connective tissue
0.011 0.988 0.000
M54.6 Pain in thoracic spine
0.011 0.989 0.000
M45-M49 Spondylopathies
0.011 0.989 0.000
O20.0 Threatened abortion
0.011 0.989 0.000
M79.8 Other specified soft tissue disorders
0.011 0.989 0.000
M54.9 Dorsalgia, unspecified
0.011 0.989 0.000
M79.6 Pain in limb
0.011 0.989 0.000
M79.60 Pain in limb (Multiple sites)
0.011 0.989 0.000
M86-M90 Other osteopathies
0.011 0.989 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.011 0.989 0.000
M54.89 Other dorsalgia (Site unspecified)
0.011 0.989 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.011 0.989 0.000
M54.54 Low back pain-Thoracic
0.010 0.989 0.000
M54.53 Low back pain-Cervicothoracic
0.010 0.989 0.000
M54.52 Low back pain-Cervical
0.010 0.989 0.000
M54.51 Low back pain-Occipit-atl-axl
0.010 0.989 0.000
O20 Haemorrhage in early pregnancy
0.011 0.989 0.000
M53 Other dorsopathies, not elsewhere classified
0.010 0.990 0.000
M54.50 Low back pain (Multiple sites in spine)
0.010 0.990 0.000
M70-M79 Other soft tissue disorders
0.010 0.990 0.000
M54.55 Low back pain (Thoracolumbar region)
0.010 0.990 0.000
D73.5 Infarction of spleen
0.010 0.990 0.000
M79.7 Fibromyalgia
0.010 0.990 0.000
E87.2 Acidosis
0.010 0.990 0.000
D70 Agranulocytosis
0.010 0.990 0.000
D23.1 Skin of eyelid, including canthus
0.010 0.990 0.000
M80-M85 Disorders of bone density and structure
0.010 0.990 0.000
M20-M25 Other joint disorders
0.010 0.990 0.000
M79.63 Pain in limb (Forearm)
0.010 0.990 0.000
M89 Other disorders of bone
0.010 0.990 0.000
M79.2 Neuralgia and neuritis, unspecified
0.010 0.990 0.000
D55-D59 Haemolytic anaemias
0.010 0.990 0.000
M60-M63 Disorders of muscles
0.010 0.990 0.000
D73.0 Hyposplenism
0.010 0.990 0.000
M45 Ankylosing spondylitis
0.010 0.990 0.000
O24 Diabetes mellitus in pregnancy
0.010 0.990 0.000
O21 Excessive vomiting in pregnancy
0.010 0.990 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.010 0.990 0.000
M54.4 Lumbago with sciatica
0.010 0.990 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.010 0.990 0.000
M79.68 Pain in limb (Other)
0.010 0.990 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.010 0.990 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.009 0.990 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.009 0.990 0.000
M54.86 Other dorsalgia (Lumbar region)
0.009 0.990 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.009 0.990 0.000
M54.84 Other dorsalgia (Thoracic region)
0.009 0.990 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.009 0.990 0.000
M54.82 Other dorsalgia (Cervical region)
0.009 0.990 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.009 0.990 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.009 0.990 0.000
M79.67 Pain in limb (Ankle and foot)
0.010 0.990 0.000
O23 Infections of genito-urinary tract in pregnancy
0.009 0.990 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.009 0.991 0.000
M35.0 Sicca syndrome [Sjogren]
0.009 0.991 0.000
M79.1 Myalgia
0.009 0.991 0.000
M79.79 Fibromyalgia (Site unspecified)
0.009 0.991 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.009 0.991 0.000
M54.2 Cervicalgia
0.009 0.991 0.000
M84 Disorders of continuity of bone
0.009 0.991 0.000
H61 Other disorders of external ear
0.009 0.991 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.009 0.991 0.000
M35.1 Other overlap syndromes
0.009 0.991 0.000
M79.61 Pain in limb (Shoulder region)
0.009 0.991 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.009 0.991 0.000
D74 Methaemoglobinaemia
0.009 0.991 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.009 0.991 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.009 0.991 0.000
M34 Systemic sclerosis
0.009 0.991 0.000
M00-M03 Infectious arthropathies
0.009 0.991 0.000
D60-D64 Aplastic and other anaemias
0.009 0.991 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.009 0.991 0.000
D75 Other diseases of blood and blood-forming organs
0.009 0.991 0.000
M54.1 Radiculopathy
0.009 0.991 0.000
M47 Spondylosis
0.009 0.991 0.000
D80-D89 Certain disorders involving the immune mechanism
0.009 0.991 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.009 0.991 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.009 0.991 0.000
M31 Other necrotising vasculopathies
0.009 0.991 0.000
O21.0 Mild hyperemesis gravidarum
0.009 0.991 0.000
M48 Other spondylopathies
0.009 0.991 0.000
M90 Osteopathies in diseases classified elsewhere
0.009 0.991 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.009 0.991 0.000
M54.56 Low back pain (Lumbar region)
0.009 0.991 0.000
M89.8 Other specified disorders of bone
0.009 0.991 0.000
M79.9 Soft tissue disorder, unspecified
0.009 0.991 0.000
M79.3 Panniculitis, unspecified
0.009 0.991 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.009 0.991 0.000
M49 Spondylopathies in diseases classified elsewhere
0.009 0.991 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.009 0.991 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.008 0.991 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.008 0.991 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.008 0.991 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.008 0.991 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.008 0.991 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.008 0.991 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.008 0.991 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.008 0.991 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.008 0.991 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.008 0.991 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.009 0.991 0.000
H61.2 Impacted cerumen
0.009 0.991 0.000
D73.9 Disease of spleen, unspecified
0.008 0.991 0.000
D73.8 Other diseases of spleen
0.008 0.991 0.000
D73.4 Cyst of spleen
0.008 0.991 0.000
D73.3 Abscess of spleen
0.008 0.991 0.000
D73.2 Chronic congestive splenomegaly
0.008 0.991 0.000
D73.1 Hypersplenism
0.008 0.991 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.008 0.991 0.000
M35.8 Other specified systemic involvement of connective tissue
0.008 0.991 0.000
M35.7 Hypermobility syndrome
0.008 0.991 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.008 0.991 0.000
M35.5 Multifocal fibrosclerosis
0.008 0.991 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.008 0.991 0.000
M35.2 Behcet's disease
0.008 0.991 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.008 0.992 0.000
M62 Other disorders of muscle
0.008 0.992 0.000
M89.9 Disorder of bone, unspecified
0.008 0.992 0.000
M47.1 Other spondylosis with myelopathy
0.008 0.992 0.000
M88 Paget's disease of bone [osteitis deformans]
0.008 0.992 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.008 0.992 0.000
M91-M94 Chondropathies
0.008 0.992 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.008 0.992 0.000
H61.3 Acquired stenosis of external ear canal
0.008 0.992 0.000
M84.0 Malunion of fracture
0.008 0.992 0.000
M54.69 Pain in thoracic spine-Site unspe
0.008 0.992 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.008 0.992 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.008 0.992 0.000
M54.66 Pain in thoracic spine-Lumbar
0.008 0.992 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.008 0.992 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.008 0.992 0.000
M54.62 Pain in thoracic spine-Cervical
0.008 0.992 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.008 0.992 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.008 0.992 0.000
M86 Osteomyelitis
0.008 0.992 0.000
M46 Other inflammatory spondylopathies
0.008 0.992 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.008 0.992 0.000
M79.88 Other specified soft tissue disorders (Other)
0.008 0.992 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.008 0.992 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.008 0.992 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.008 0.992 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.008 0.992 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.008 0.992 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.008 0.992 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.008 0.992 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.008 0.992 0.000
O29 Complications of anaesthesia during pregnancy
0.008 0.992 0.000
O22 Venous complications in pregnancy
0.008 0.992 0.000
O25 Malnutrition in pregnancy
0.008 0.992 0.000
M31.9 Necrotising vasculopathy, unspecified
0.008 0.992 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.008 0.992 0.000
M21 Other acquired deformities of limbs
0.008 0.992 0.000
M33 Dermatopolymyositis
0.008 0.992 0.000
O15 Eclampsia
0.008 0.992 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.008 0.992 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.008 0.992 0.000
M76 Enthesopathies of lower limb, excluding foot
0.008 0.992 0.000
D61 Other aplastic anaemias
0.008 0.992 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.008 0.992 0.000
M40-M43 Deforming dorsopathies
0.008 0.992 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.008 0.992 0.000
H60-H62 Diseases of external ear
0.008 0.992 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.008 0.992 0.000
M31.3 Wegener's granulomatosis
0.008 0.992 0.000
O28 Abnormal findings on antenatal screening of mother
0.008 0.992 0.000
H61.0 Perichondritis of external ear
0.008 0.992 0.000
M72 Fibroblastic disorders
0.008 0.992 0.000
M80 Osteoporosis with pathological fracture
0.008 0.992 0.000
D75.0 Familial erythrocytosis
0.008 0.992 0.000
M53.9 Dorsopathy, unspecified
0.007 0.992 0.000
M53.8 Other specified dorsopathies
0.007 0.992 0.000
M53.2 Spinal instabilities
0.007 0.992 0.000
M53.1 Cervicobrachial syndrome
0.007 0.992 0.000
M53.0 Cervicocranial syndrome
0.007 0.992 0.000
M82 Osteoporosis in diseases classified elsewhere
0.008 0.992 0.000
D75.1 Secondary polycythaemia
0.008 0.992 0.000
M34.8 Other forms of systemic sclerosis
0.008 0.992 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.008 0.992 0.000
M34.9 Systemic sclerosis, unspecified
0.008 0.992 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.008 0.992 0.000
O21.9 Vomiting of pregnancy, unspecified
0.007 0.992 0.000
M79.78 Fibromyalgia (Other)
0.007 0.992 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.007 0.992 0.000
M79.76 Fibromyalgia (Lower leg)
0.007 0.992 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.007 0.992 0.000
M79.74 Fibromyalgia (Hand)
0.007 0.992 0.000
M79.73 Fibromyalgia (Forearm)
0.007 0.992 0.000
M79.72 Fibromyalgia (Upper arm)
0.007 0.992 0.000
M79.71 Fibromyalgia (Shoulder region)
0.007 0.992 0.000
M77 Other enthesopathies
0.007 0.992 0.000
M79.16 Myalgia (Lower leg)
0.007 0.992 0.000
H61.1 Non-infective disorders of pinna
0.007 0.992 0.000
M83 Adult osteomalacia
0.007 0.992 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.007 0.992 0.000
H61.9 Disorder of external ear, unspecified
0.007 0.992 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.007 0.993 0.000
M32 Systemic lupus erythematosus
0.007 0.993 0.000
M30 Polyarteritis nodosa and related conditions
0.007 0.993 0.000
M34.1 CR(E)ST syndrome
0.007 0.993 0.000
M89.6 Osteopathy after poliomyelitis
0.007 0.993 0.000
M89.5 Osteolysis
0.007 0.993 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.007 0.993 0.000
M89.3 Hypertrophy of bone
0.007 0.993 0.000
M89.2 Other disorders of bone development and growth
0.007 0.993 0.000
M89.1 Epiphyseal arrest
0.007 0.993 0.000
M89.0 Algoneurodystrophy
0.007 0.993 0.000
M90.7 Fracture of bone in neoplastic disease
0.007 0.993 0.000
D72 Other disorders of white blood cells
0.007 0.993 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.007 0.993 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.007 0.993 0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.007 0.993 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.007 0.993 0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.007 0.993 0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.007 0.993 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.007 0.993 0.000
M79.10 Myalgia (Multiple sites)
0.007 0.993 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.007 0.993 0.000
D58 Other hereditary haemolytic anaemias
0.007 0.993 0.000
D57 Sickle-cell disorders
0.007 0.993 0.000
D56 Thalassaemia
0.007 0.993 0.000
D55 Anaemia due to enzyme disorders
0.007 0.993 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.007 0.993 0.000
M61 Calcification and ossification of muscle
0.007 0.993 0.000
M60 Myositis
0.007 0.993 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.007 0.993 0.000
M85 Other disorders of bone density and structure
0.007 0.993 0.000
M71 Other bursopathies
0.007 0.993 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.007 0.993 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.007 0.993 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.007 0.993 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.007 0.993 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.007 0.993 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.007 0.993 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.007 0.993 0.000
O21.8 Other vomiting complicating pregnancy
0.007 0.993 0.000
O21.2 Late vomiting of pregnancy
0.007 0.993 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.007 0.993 0.000
O24.9 Diabetes mellitus in pregnancy, unspecified
0.007 0.993 0.000
O24.3 Pre-existing diabetes mellitus, unspecified
0.007 0.993 0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus
0.007 0.993 0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent
0.007 0.993 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.007 0.993 0.000
M48.0 Spinal stenosis
0.007 0.993 0.000
M79.5 Residual foreign body in soft tissue
0.007 0.993 0.000
M89.88 Other specified disorders of bone (Other)
0.007 0.993 0.000
M84.03 Malunion of fracture (Forearm)
0.007 0.993 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.007 0.993 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.007 0.993 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.007 0.993 0.000
M54.44 Lumbago with sciatica-Thoracic
0.007 0.993 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.007 0.993 0.000
M54.42 Lumbago with sciatica-Cervical
0.007 0.993 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.007 0.993 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.007 0.993 0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec
0.007 0.993 0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)
0.007 0.993 0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)
0.007 0.993 0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)
0.007 0.993 0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)
0.007 0.993 0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)
0.007 0.993 0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)
0.007 0.993 0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)
0.007 0.993 0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)
0.007 0.993 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.007 0.993 0.000
D61.9 Aplastic anaemia, unspecified
0.007 0.993 0.000
O20.8 Other haemorrhage in early pregnancy
0.007 0.993 0.000
M79.19 Myalgia (Site unspecified)
0.007 0.993 0.000
E20-E35 Disorders of other endocrine glands
0.007 0.993 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.007 0.993 0.000
M00 Pyogenic arthritis
0.007 0.993 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.007 0.993 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.007 0.993 0.000
O23.3 Infections of other parts of urinary tract in pregnancy
0.007 0.993 0.000
O23.2 Infections of urethra in pregnancy
0.007 0.993 0.000
O23.1 Infections of bladder in pregnancy
0.007 0.993 0.000
O23.0 Infections of kidney in pregnancy
0.007 0.993 0.000
M24 Other specific joint derangements
0.007 0.993 0.000
M47.2 Other spondylosis with radiculopathy
0.007 0.993 0.000
M87 Osteonecrosis
0.007 0.993 0.000
M79.17 Myalgia (Ankle and foot)
0.007 0.993 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.007 0.993 0.000
M79.14 Myalgia (Hand)
0.007 0.993 0.000
M79.13 Myalgia (Forearm)
0.007 0.993 0.000
M79.12 Myalgia (Upper arm)
0.007 0.993 0.000
M79.11 Myalgia (Shoulder region)
0.007 0.993 0.000
M79.70 Fibromyalgia (Multiple sites)
0.007 0.993 0.000
M84.01 Malunion of fracture (Shoulder region)
0.007 0.993 0.000
D84 Other immunodeficiencies
0.007 0.993 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.007 0.993 0.000
M54.27 Cervicalgia-Lumbosacral
0.007 0.993 0.000
M54.26 Cervicalgia-Lumbar
0.007 0.993 0.000
M54.25 Cervicalgia-Thoracolumbar
0.007 0.993 0.000
M54.24 Cervicalgia-Thoracic
0.007 0.993 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.007 0.993 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.007 0.993 0.000
M54.20 Cervicalgia-Mult site
0.007 0.993 0.000
E83.4 Disorders of magnesium metabolism
0.007 0.993 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.007 0.993 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.007 0.993 0.000
M84.9 Disorder of continuity of bone, unspecified
0.007 0.993 0.000
M84.8 Other disorders of continuity of bone
0.007 0.993 0.000
M84.4 Pathological fracture, not elsewhere classified
0.007 0.993 0.000
M84.3 Stress fracture, not elsewhere classified
0.007 0.993 0.000
M84.2 Delayed union of fracture
0.007 0.993 0.000
O14.9 Preeclampsia, unspecified
0.007 0.993 0.000
D23.7 Skin of lower limb, including hip
0.007 0.993 0.000
M89.98 Disorder of bone, unspecified (Other)
0.007 0.993 0.000
E23 Hypofunction and other disorders of pituitary gland
0.007 0.993 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.007 0.993 0.000
M21.4 Flat foot [pes planus] (acquired)
0.007 0.993 0.000
D74.9 Methaemoglobinaemia, unspecified
0.007 0.993 0.000
D74.8 Other methaemoglobinaemias
0.007 0.993 0.000
D74.0 Congenital methaemoglobinaemia
0.007 0.993 0.000
D76.3 Other histiocytosis syndromes
0.007 0.993 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.007 0.993 0.000
D76.1 Haemophagocytic lymphohistiocytosis
0.007 0.993 0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.007 0.993 0.000
D59 Acquired haemolytic anaemia
0.007 0.993 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.007 0.993 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.007 0.993 0.000
M34.0 Progressive systemic sclerosis
0.007 0.993 0.000
O85-O92 Complications predominantly related to the puerperium
0.007 0.993 0.000
Chapter VIII Diseases of the ear and mastoid process
0.007 0.993 0.000
H61.8 Other specified disorders of external ear
0.007 0.993 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.007 0.993 0.000
M02 Reactive arthropathies
0.007 0.993 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.007 0.993 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.007 0.993 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.007 0.993 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.006 0.993 0.000
M79.0 Rheumatism, unspecified
0.007 0.993 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.007 0.993 0.000
M54.14 Radiculopathy (Thoracic region)
0.007 0.993 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.007 0.993 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.007 0.993 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.007 0.993 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.007 0.993 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.007 0.993 0.000
D83 Common variable immunodeficiency
0.007 0.993 0.000
D82 Immunodeficiency associated with other major defects
0.007 0.993 0.000
D81 Combined immunodeficiencies
0.007 0.993 0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)
0.007 0.993 0.000
M31.8 Other specified necrotising vasculopathies
0.007 0.993 0.000
M31.7 Microscopic polyangiitis
0.007 0.993 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.007 0.993 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.007 0.993 0.000
M31.2 Lethal midline granuloma
0.007 0.993 0.000
M31.1 Thrombotic microangiopathy
0.007 0.993 0.000
M31.0 Hypersensitivity angiitis
0.007 0.993 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.006 0.993 0.000
M21.3 Wrist or foot drop (acquired)
0.007 0.993 0.000
M48.9 Spondylopathy, unspecified
0.007 0.993 0.000
M48.8 Other specified spondylopathies
0.007 0.993 0.000
M48.4 Fatigue fracture of vertebra
0.007 0.993 0.000
M48.3 Traumatic spondylopathy
0.007 0.993 0.000
M48.2 Kissing spine
0.007 0.993 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.007 0.993 0.000
M72.2 Plantar fascial fibromatosis
0.007 0.993 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.006 0.993 0.000
M90.6 Osteitis deformans in neoplastic disease
0.006 0.993 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.006 0.993 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.006 0.993 0.000
M90.3 Osteonecrosis in caisson disease
0.006 0.993 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.006 0.993 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.006 0.993 0.000
M90.0 Tuberculosis of bone
0.006 0.993 0.000
O14.0 Moderate preeclampsia
0.007 0.993 0.000
M33.1 Other dermatomyositis
0.006 0.993 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.007 0.993 0.000
M79.18 Myalgia (Other)
0.006 0.993 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.006 0.993 0.000
M86.6 Other chronic osteomyelitis
0.006 0.993 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.006 0.993 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.006 0.993 0.000
M89.84 Other specified disorders of bone (Hand)
0.006 0.993 0.000
M89.83 Other specified disorders of bone (Forearm)
0.006 0.993 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.006 0.993 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.006 0.993 0.000
M88.9 Paget's disease of bone, unspecified
0.006 0.993 0.000
E22 Hyperfunction of pituitary gland
0.007 0.993 0.000
M79.39 Panniculitis, unspecified (Site unspecified)
0.006 0.993 0.000
M79.38 Panniculitis, unspecified (Other)
0.006 0.993 0.000
M79.37 Panniculitis, unspecified (Ankle and foot)
0.006 0.993 0.000
M79.36 Panniculitis, unspecified (Lower leg)
0.006 0.993 0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)
0.006 0.993 0.000
M79.34 Panniculitis, unspecified (Hand)
0.006 0.993 0.000
M79.33 Panniculitis, unspecified (Forearm)
0.006 0.993 0.000
M79.32 Panniculitis, unspecified (Upper arm)
0.006 0.993 0.000
M79.31 Panniculitis, unspecified (Shoulder region)
0.006 0.993 0.000
M79.30 Panniculitis, unspecified (Multiple sites)
0.006 0.993 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.006 0.993 0.000
M79.98 Soft tissue disorder, unspecified (Other)
0.006 0.993 0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)
0.006 0.993 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.006 0.993 0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)
0.006 0.993 0.000
M79.94 Soft tissue disorder, unspecified (Hand)
0.006 0.993 0.000
M79.93 Soft tissue disorder, unspecified (Forearm)
0.006 0.993 0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)
0.006 0.993 0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)
0.006 0.993 0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)
0.006 0.993 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.006 0.993 0.000
M77.4 Metatarsalgia
0.006 0.993 0.000
O12.1 Gestational proteinuria
0.006 0.993 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.007 0.993 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.006 0.993 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.006 0.993 0.000
M49.4 Neuropathic spondylopathy
0.006 0.993 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.006 0.993 0.000
M49.2 Enterobacterial spondylitis
0.006 0.993 0.000
M49.1 Brucella spondylitis
0.006 0.993 0.000
M49.0 Tuberculosis of spine
0.006 0.993 0.000
M46.4 Discitis, unspecified
0.006 0.993 0.000
M62.8 Other specified disorders of muscle
0.006 0.993 0.000
O14.2 HELLP syndrome
0.006 0.993 0.000
O14.1 Severe preeclampsia
0.006 0.993 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.006 0.993 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.006 0.994 0.000
D86 Sarcoidosis
0.006 0.994 0.000
M48.04 Spinal stenosis (Thoracic region)
0.006 0.994 0.000
M54.19 Radiculopathy (Site unspecified)
0.006 0.994 0.000
E28 Ovarian dysfunction
0.006 0.994 0.000
O23.5 Infections of the genital tract in pregnancy
0.006 0.994 0.000
D23 Other benign neoplasms of skin
0.006 0.994 0.000
H65-H75 Diseases of middle ear and mastoid
0.006 0.994 0.000
M90.78 Fracture of bone in neoplastic disease (Other)
0.006 0.994 0.000
M21.1 Varus deformity, not elsewhere classified
0.006 0.994 0.000
O12.0 Gestational oedema
0.006 0.994 0.000
E83 Disorders of mineral metabolism
0.006 0.994 0.000
M76.6 Achilles tendinitis
0.006 0.994 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.006 0.994 0.000
D62 Acute posthaemorrhagic anaemia
0.006 0.994 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.006 0.994 0.000
M62.9 Disorder of muscle, unspecified
0.006 0.994 0.000
M62.6 Muscle strain
0.006 0.994 0.000
M62.4 Contracture of muscle
0.006 0.994 0.000
M62.3 Immobility syndrome (paraplegic)
0.006 0.994 0.000
M62.2 Ischaemic infarction of muscle
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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