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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4583981
log Bayes Factor = 58.3312
Chromosome 6   position 26,992,023  (GRCh37) Explore rs4583981 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10.9 Without complications
0.988 0.012 0.000
E10 Insulin-dependent diabetes mellitus
0.982 0.018 0.000
K90 Intestinal malabsorption
0.950 0.050 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.922 0.078 0.000
E10-E14 Diabetes mellitus
0.876 0.124 0.000
K90.9 Intestinal malabsorption, unspecified
0.873 0.127 0.000
E10.6 With other specified complications
0.858 0.142 0.000
R31 Unspecified haematuria
0.000 0.148 0.852
E10.3 With ophthalmic complications
0.842 0.158 0.000
E16.2 Hypoglycaemia, unspecified
0.824 0.176 0.000
E16 Other disorders of pancreatic internal secretion
0.815 0.185 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.809 0.191 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.806 0.194 0.000
E10.2 With renal complications
0.790 0.210 0.000
E10.7 With multiple complications
0.790 0.210 0.000
E10.4 With neurological complications
0.778 0.222 0.000
E14 Unspecified diabetes mellitus
0.769 0.231 0.000
E10.5 With peripheral circulatory complications
0.757 0.243 0.000
E10.1 With ketoacidosis
0.757 0.243 0.000
E10.8 With unspecified complications
0.747 0.253 0.000
E20-E35 Disorders of other endocrine glands
0.742 0.258 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.686 0.314 0.000
E10.0 With coma
0.684 0.316 0.000
K90.3 Pancreatic steatorrhoea
0.681 0.319 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.681 0.319 0.000
K90.1 Tropical sprue
0.681 0.319 0.000
E13 Other specified diabetes mellitus
0.667 0.332 0.000
E21.0 Primary hyperparathyroidism
0.641 0.359 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.635 0.365 0.000
E14.5 With peripheral circulatory complications
0.631 0.369 0.000
E12 Malnutrition-related diabetes mellitus
0.628 0.372 0.000
E14.1 With ketoacidosis
0.621 0.379 0.000
E14.6 With other specified complications
0.617 0.382 0.000
E14.3 With ophthalmic complications
0.600 0.400 0.000
K90.8 Other intestinal malabsorption
0.594 0.405 0.000
E14.2 Withrenal complications
0.592 0.408 0.000
E28 Ovarian dysfunction
0.587 0.413 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.584 0.416 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.584 0.416 0.000
E16.4 Abnormal secretion of gastrin
0.584 0.416 0.000
E16.3 Increased secretion of glucagon
0.584 0.416 0.000
E14.8 With unspecified complications
0.582 0.417 0.000
E40-E46 Malnutrition
0.581 0.419 0.000
E15 Nondiabetic hypoglycaemic coma
0.580 0.420 0.000
E23 Hypofunction and other disorders of pituitary gland
0.575 0.425 0.000
E25 Adrenogenital disorders
0.571 0.429 0.000
E31 Polyglandular dysfunction
0.567 0.433 0.000
E21.3 Hyperparathyroidism, unspecified
0.566 0.434 0.000
E14.4 With neurological complications
0.555 0.445 0.000
E26 Hyperaldosteronism
0.554 0.446 0.000
E14.7 With multiple complications
0.551 0.448 0.000
E14.0 With coma
0.551 0.448 0.000
E13.9 Without complications
0.550 0.450 0.000
E22 Hyperfunction of pituitary gland
0.543 0.457 0.000
E24 Cushing's syndrome
0.536 0.463 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.532 0.468 0.000
E32 Diseases of thymus
0.532 0.468 0.000
E30 Disorders of puberty, not elsewhere classified
0.532 0.468 0.000
E21.4 Other specified disorders of parathyroid gland
0.530 0.469 0.000
E27 Other disorders of adrenal gland
0.524 0.476 0.000
E34 Other endocrine disorders
0.508 0.492 0.000
E16.1 Other hypoglycaemia
0.506 0.494 0.000
E23.2 Diabetes insipidus
0.503 0.497 0.000
E28.2 Polycystic ovarian syndrome
0.502 0.498 0.000
N40 Hyperplasia of prostate
0.000 0.500 0.500
E50-E64 Other nutritional deficiencies
0.494 0.506 0.000
E13.8 With unspecified complications
0.479 0.521 0.000
E13.7 With multiple complications
0.479 0.521 0.000
E13.6 With other specified complications
0.479 0.521 0.000
E13.5 With peripheral circulatory complications
0.479 0.521 0.000
E13.4 With neurological complications
0.479 0.521 0.000
E13.2 With renal complications
0.479 0.521 0.000
E13.1 With ketoacidosis
0.479 0.521 0.000
E13.0 With coma
0.479 0.521 0.000
E23.6 Other disorders of pituitary gland
0.479 0.521 0.000
E20 Hypoparathyroidism
0.477 0.523 0.000
E22.1 Hyperprolactinaemia
0.470 0.530 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.469 0.531 0.000
E27.1 Primary adrenocortical insufficiency
0.464 0.536 0.000
E21.2 Other hyperparathyroidism
0.458 0.542 0.000
E24.2 Drug-induced Cushing's syndrome
0.458 0.542 0.000
E12.9 Without complications
0.450 0.550 0.000
E12.8 With unspecified complications
0.450 0.550 0.000
E12.7 With multiple complications
0.450 0.550 0.000
E12.6 With other specified complications
0.450 0.550 0.000
E12.5 With peripheral circulatory complications
0.450 0.550 0.000
E12.4 With neurological complications
0.450 0.550 0.000
E12.3 With ophthalmic complications
0.450 0.550 0.000
E12.2 With renal complications
0.450 0.550 0.000
E12.1 With ketoacidosis
0.450 0.550 0.000
E12.0 With coma
0.450 0.550 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.449 0.551 0.000
E31.0 Autoimmune polyglandular failure
0.442 0.558 0.000
E26.0 Primary hyperaldosteronism
0.442 0.558 0.000
E13.3 With ophthalmic complications
0.427 0.573 0.000
E28.9 Ovarian dysfunction, unspecified
0.421 0.579 0.000
E28.8 Other ovarian dysfunction
0.421 0.579 0.000
E28.1 Androgen excess
0.421 0.579 0.000
E28.0 Oestrogen excess
0.421 0.579 0.000
E46 Unspecified protein-energy malnutrition
0.420 0.580 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.419 0.581 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.417 0.582 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.417 0.583 0.000
E45 Retarded development following protein-energy malnutrition
0.417 0.583 0.000
E43 Unspecified severe protein-energy malnutrition
0.417 0.583 0.000
E42 Marasmic kwashiorkor
0.417 0.583 0.000
E41 Nutritional marasmus
0.417 0.583 0.000
E40 Kwashiorkor
0.417 0.583 0.000
E34.8 Other specified endocrine disorders
0.414 0.586 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.412 0.588 0.000
E23.1 Drug-induced hypopituitarism
0.412 0.588 0.000
E25.9 Adrenogenital disorder, unspecified
0.410 0.590 0.000
E25.8 Other adrenogenital disorders
0.410 0.590 0.000
E31.9 Polyglandular dysfunction, unspecified
0.407 0.593 0.000
E31.8 Other polyglandular dysfunction
0.407 0.593 0.000
E31.1 Polyglandular hyperfunction
0.407 0.593 0.000
E24.8 Other Cushing's syndrome
0.399 0.601 0.000
E26.8 Other hyperaldosteronism
0.397 0.603 0.000
E26.1 Secondary hyperaldosteronism
0.397 0.603 0.000
E22.0 Acromegaly and pituitary gigantism
0.393 0.607 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.389 0.610 0.000
E22.8 Other hyperfunction of pituitary gland
0.389 0.610 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.385 0.615 0.000
E24.3 Ectopic ACTH syndrome
0.385 0.615 0.000
E24.1 Nelson's syndrome
0.385 0.615 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.382 0.618 0.000
E30.9 Disorder of puberty, unspecified
0.381 0.618 0.000
E30.8 Other disorders of puberty
0.381 0.618 0.000
E30.1 Precocious puberty
0.381 0.618 0.000
E30.0 Delayed puberty
0.381 0.618 0.000
E32.9 Disease of thymus, unspecified
0.381 0.618 0.000
E32.8 Other diseases of thymus
0.381 0.618 0.000
E32.1 Abscess of thymus
0.381 0.618 0.000
E32.0 Persistent hyperplasia of thymus
0.381 0.618 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.381 0.618 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.381 0.618 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.381 0.618 0.000
E29 Testicular dysfunction
0.380 0.619 0.001
E61 Deficiency of other nutrient elements
0.380 0.620 0.000
E27.5 Adrenomedullary hyperfunction
0.376 0.624 0.000
E27.0 Other adrenocortical overactivity
0.376 0.624 0.000
E28.3 Primary ovarian failure
0.371 0.629 0.000
E56 Other vitamin deficiencies
0.370 0.630 0.000
E26.9 Hyperaldosteronism, unspecified
0.366 0.634 0.000
E34.5 Androgen resistance syndrome
0.364 0.635 0.000
E34.4 Constitutional tall stature
0.364 0.635 0.000
E34.3 Short stature, not elsewhere classified
0.364 0.635 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.364 0.635 0.000
E34.1 Other hypersecretion of intestinal hormones
0.364 0.635 0.000
E24.0 Pituitary-dependent Cushing's disease
0.357 0.642 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.354 0.646 0.000
E63 Other nutritional deficiencies
0.354 0.646 0.000
E50 Vitamin A deficiency
0.354 0.646 0.000
E60 Dietary zinc deficiency
0.354 0.646 0.000
E59 Dietary selenium deficiency
0.354 0.646 0.000
E54 Ascorbic acid deficiency
0.354 0.646 0.000
E52 Niacin deficiency [pellagra]
0.354 0.646 0.000
E51 Thiamine deficiency
0.352 0.648 0.000
E55 Vitamin D deficiency
0.348 0.652 0.000
E34.0 Carcinoid syndrome
0.346 0.654 0.000
E20.8 Other hypoparathyroidism
0.342 0.658 0.000
E20.1 Pseudohypoparathyroidism
0.342 0.658 0.000
E20.0 Idiopathic hypoparathyroidism
0.342 0.658 0.000
E27.2 Addisonian crisis
0.334 0.665 0.000
E58 Dietary calcium deficiency
0.334 0.665 0.000
E23.7 Disorder of pituitary gland, unspecified
0.317 0.682 0.000
E61.1 Iron deficiency
0.314 0.686 0.000
E27.9 Disorder of adrenal gland, unspecified
0.310 0.690 0.000
E44.1 Mild protein-energy malnutrition
0.299 0.701 0.000
E44.0 Moderate protein-energy malnutrition
0.299 0.701 0.000
E14.9 Without complications
0.297 0.703 0.000
E29.9 Testicular dysfunction, unspecified
0.291 0.708 0.001
E23.0 Hypopituitarism
0.289 0.711 0.000
E20.9 Hypoparathyroidism, unspecified
0.287 0.712 0.000
E34.9 Endocrine disorder, unspecified
0.282 0.717 0.000
E56.1 Deficiency of vitamin K
0.281 0.719 0.000
N40-N51 Diseases of male genital organs
0.000 0.726 0.274
E29.8 Other testicular dysfunction
0.272 0.727 0.001
E29.0 Testicular hyperfunction
0.272 0.727 0.001
E61.9 Deficiency of nutrient element, unspecified
0.273 0.727 0.000
E61.8 Deficiency of other specified nutrient elements
0.273 0.727 0.000
E61.7 Deficiency of multiple nutrient elements
0.273 0.727 0.000
E61.6 Vanadium deficiency
0.273 0.727 0.000
E61.5 Molybdenum deficiency
0.273 0.727 0.000
E61.4 Chromium deficiency
0.273 0.727 0.000
E61.3 Manganese deficiency
0.273 0.727 0.000
E61.0 Copper deficiency
0.273 0.727 0.000
E24.9 Cushing's syndrome, unspecified
0.271 0.729 0.000
E56.9 Vitamin deficiency, unspecified
0.265 0.735 0.000
E56.8 Deficiency of other vitamins
0.265 0.735 0.000
E56.0 Deficiency of vitamin E
0.265 0.735 0.000
N45 Orchitis and epididymitis
0.000 0.742 0.258
E50.9 Vitamin A deficiency, unspecified
0.254 0.746 0.000
E50.8 Other manifestations of vitamin A deficiency
0.254 0.746 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.254 0.746 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.254 0.746 0.000
E50.5 Vitamin A deficiency with night blindness
0.254 0.746 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.254 0.746 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.254 0.746 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.254 0.746 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.254 0.746 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.254 0.746 0.000
E63.9 Nutritional deficiency, unspecified
0.254 0.746 0.000
E63.8 Other specified nutritional deficiencies
0.254 0.746 0.000
E63.1 Imbalance of constituents of food intake
0.254 0.746 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.254 0.746 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.254 0.746 0.000
E64.8 Sequelae of other nutritional deficiencies
0.254 0.746 0.000
E64.3 Sequelae of rickets
0.254 0.746 0.000
E64.2 Sequelae of vitamin C deficiency
0.254 0.746 0.000
E64.1 Sequelae of vitamin A deficiency
0.254 0.746 0.000
E64.0 Sequelae of protein-energy malnutrition
0.254 0.746 0.000
E51.9 Thiamine deficiency, unspecified
0.252 0.747 0.000
E51.8 Other manifestations of thiamine deficiency
0.252 0.747 0.000
E51.1 Beriberi
0.252 0.747 0.000
E51.2 Wernicke's encephalopathy
0.250 0.749 0.000
N41 Inflammatory diseases of prostate
0.000 0.750 0.250
E55.0 Rickets, active
0.250 0.750 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.752 0.248
E65-E68 Obesity and other hyperalimentation
0.247 0.753 0.000
E61.2 Magnesium deficiency
0.247 0.753 0.000
E55.9 Vitamin D deficiency, unspecified
0.244 0.756 0.000
N41.0 Acute prostatitis
0.000 0.758 0.242
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.758 0.242
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.239 0.761 0.000
E53 Deficiency of other B group vitamins
0.236 0.763 0.000
N42 Other disorders of prostate
0.000 0.771 0.229
E00-E07 Disorders of thyroid gland
0.228 0.772 0.000
N46 Male infertility
0.000 0.777 0.223
N42.1 Congestion and haemorrhage of prostate
0.000 0.778 0.222
E27.8 Other specified disorders of adrenal gland
0.219 0.780 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.781 0.219
N41.1 Chronic prostatitis
0.000 0.788 0.212
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.798 0.202
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.801 0.199
N44 Torsion of testis
0.000 0.801 0.199
N42.8 Other specified disorders of prostate
0.000 0.814 0.186
N41.3 Prostatocystitis
0.000 0.820 0.180
E06 Thyroiditis
0.178 0.822 0.000
E67 Other hyperalimentation
0.177 0.822 0.000
E68 Sequelae of hyperalimentation
0.177 0.822 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.830 0.170
E53.1 Pyridoxine deficiency
0.170 0.830 0.000
E53.0 Riboflavin deficiency
0.170 0.830 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.832 0.168
N42.3 Dysplasia of prostate
0.000 0.835 0.164
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.163 0.837 0.000
E00 Congenital iodine-deficiency syndrome
0.163 0.837 0.000
N41.2 Abscess of prostate
0.000 0.840 0.159
N42.0 Calculus of prostate
0.000 0.842 0.158
E53.9 Vitamin B deficiency, unspecified
0.158 0.842 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.843 0.157
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.843 0.157
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.843 0.157
N51.2 Balanitis in diseases classified elsewhere
0.000 0.854 0.146
E06.3 Autoimmune thyroiditis
0.145 0.855 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.144 0.855 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.857 0.143
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.857 0.143
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.857 0.143
N41.8 Other inflammatory diseases of prostate
0.000 0.857 0.143
E07 Other disorders of thyroid
0.142 0.858 0.000
N50 Other disorders of male genital organs
0.000 0.861 0.139
E03 Other hypothyroidism
0.137 0.863 0.000
E11 Non-insulin-dependent diabetes mellitus
0.136 0.864 0.000
N50.9 Disorder of male genital organs, unspecified
0.000 0.867 0.133
E06.9 Thyroiditis, unspecified
0.131 0.869 0.000
E83 Disorders of mineral metabolism
0.015 0.869 0.115
E06.4 Drug-induced thyroiditis
0.128 0.872 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.128 0.872 0.000
E06.1 Subacute thyroiditis
0.128 0.872 0.000
E06.0 Acute thyroiditis
0.128 0.872 0.000
E67.8 Other specified hyperalimentation
0.127 0.872 0.000
E67.3 Hypervitaminosis D
0.127 0.872 0.000
E67.2 Megavitamin-B6 syndrome
0.127 0.872 0.000
E67.1 Hypercarotenaemia
0.127 0.872 0.000
E67.0 Hypervitaminosis A
0.127 0.872 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.874 0.126
E04 Other non-toxic goitre
0.120 0.880 0.000
E06.5 Other chronic thyroiditis
0.119 0.880 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.117 0.883 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.117 0.883 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.117 0.883 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.117 0.883 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.117 0.883 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.117 0.883 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.117 0.883 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.117 0.883 0.000
E04.9 Non-toxic goitre, unspecified
0.114 0.886 0.000
N43 Hydrocele and spermatocele
0.000 0.890 0.110
N42.2 Atrophy of prostate
0.000 0.895 0.104
E11.5 With peripheral circulatory complications
0.104 0.896 0.000
E11.6 With other specified complications
0.104 0.896 0.000
E07.1 Dyshormogenetic goitre
0.102 0.898 0.000
E07.0 Hypersecretion of calcitonin
0.102 0.898 0.000
E03.8 Other specified hypothyroidism
0.102 0.898 0.000
E11.1 With ketoacidosis
0.101 0.898 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.101 0.899 0.000
E83.3 Disorders of phosphorus metabolism
0.004 0.900 0.096
E03.9 Hypothyroidism, unspecified
0.099 0.901 0.000
E03.5 Myxoedema coma
0.099 0.901 0.000
E03.4 Atrophy of thyroid (acquired)
0.099 0.901 0.000
E03.3 Postinfectious hypothyroidism
0.099 0.901 0.000
E11.7 With multiple complications
0.098 0.902 0.000
E65 Localised adiposity
0.094 0.906 0.001
E05 Thyrotoxicosis [hyperthyroidism]
0.094 0.906 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.011 0.906 0.083
E83.8 Other disorders of mineral metabolism
0.011 0.906 0.083
E83.2 Disorders of zinc metabolism
0.011 0.906 0.083
E83.0 Disorders of copper metabolism
0.011 0.906 0.083
E07.8 Other specified disorders of thyroid
0.094 0.906 0.000
E11.8 With unspecified complications
0.091 0.909 0.000
E07.9 Disorder of thyroid, unspecified
0.091 0.909 0.000
E11.0 With coma
0.089 0.911 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.087 0.913 0.000
E04.8 Other specified non-toxic goitre
0.086 0.913 0.000
N43.2 Other hydrocele
0.000 0.914 0.086
E11.2 With renal complications
0.086 0.914 0.000
N50.0 Atrophy of testis
0.000 0.916 0.084
E03.1 Congenital hypothyroidism without goitre
0.080 0.920 0.000
E53.8 Deficiency of other specified B group vitamins
0.080 0.920 0.000
N43.0 Encysted hydrocele
0.000 0.921 0.079
N43.4 Spermatocele
0.000 0.927 0.073
N43.1 Infected hydrocele
0.000 0.929 0.071
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.070 0.930 0.000
E11.3 With ophthalmic complications
0.069 0.931 0.000
E05.5 Thyroid crisis or storm
0.068 0.932 0.000
E05.4 Thyrotoxicosis factitia
0.068 0.932 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.068 0.932 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.933 0.067
E29.1 Testicular hypofunction
0.064 0.933 0.002
E05.0 Thyrotoxicosis with diffuse goitre
0.066 0.934 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.066 0.934 0.000
E66 Obesity
0.064 0.936 0.000
E11.4 With neurological complications
0.063 0.937 0.000
T39.1 4-Aminophenol derivatives
0.000 0.938 0.062
K90-K93 Other diseases of the digestive system
0.061 0.939 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.946 0.054
E04.0 Non-toxic diffuse goitre
0.053 0.947 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.948 0.052
E66.0 Obesity due to excess calories
0.052 0.948 0.000
E05.8 Other thyrotoxicosis
0.048 0.951 0.000
E04.1 Non-toxic single thyroid nodule
0.047 0.953 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.953 0.047
E66.1 Drug-induced obesity
0.046 0.954 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.954 0.046
E66.2 Extreme obesity with alveolar hypoventilation
0.046 0.954 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.956 0.044
K93 Disorders of other digestive organs in diseases classified elsewhere
0.044 0.956 0.000
I83 Varicose veins of lower extremities
0.000 0.960 0.040
E05.9 Thyrotoxicosis, unspecified
0.040 0.960 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.960 0.040
T39.4 Antirheumatics, not elsewhere classified
0.000 0.961 0.039
T39.2 Pyrazolone derivatives
0.000 0.961 0.039
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.962 0.038
E70-E90 Metabolic disorders
0.037 0.962 0.000
E04.2 Non-toxic multinodular goitre
0.037 0.963 0.000
D32.9 Meninges, unspecified
0.037 0.963 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.965 0.035
E83.4 Disorders of magnesium metabolism
0.010 0.966 0.024
T50.8 Diagnostic agents
0.000 0.967 0.033
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.968 0.032
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.032 0.968 0.000
K93.1 Megacolon in Chagas' disease
0.032 0.968 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.032 0.968 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.968 0.032
W20-W49 Exposure to inanimate mechanical forces
0.032 0.968 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.969 0.031
W23 Caught, crushed, jammed or pinched in or between objects
0.031 0.969 0.000
T40.2 Other opioids
0.000 0.970 0.030
E87.3 Alkalosis
0.030 0.970 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.030 0.970 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.030 0.970 0.000
E84 Cystic fibrosis
0.030 0.970 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.029 0.971 0.000
W21 Striking against or struck by sports equipment
0.029 0.971 0.000
W49.0 Home
0.029 0.971 0.000
E70 Disorders of aromatic amino-acid metabolism
0.028 0.972 0.000
E89.2 Postprocedural hypoparathyroidism
0.028 0.972 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.028 0.972 0.000
E72 Other disorders of amino-acid metabolism
0.027 0.972 0.000
T50.7 Analeptics and opioid receptor antagonists
0.000 0.972 0.028
T50.5 Appetite depressants
0.000 0.972 0.028
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.972 0.028
T50.0 Mineralocorticoids and their antagonists
0.000 0.972 0.028
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.972 0.028
T50.4 Drugs affecting uric acid metabolism
0.000 0.972 0.027
E77 Disorders of glycoprotein metabolism
0.027 0.973 0.000
E76 Disorders of glycosaminoglycan metabolism
0.027 0.973 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.027 0.973 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.027 0.973 0.000
W23.4 Street and highway
0.027 0.973 0.000
W29 Contact with other powered hand tools and household machinery
0.027 0.973 0.000
E87.0 Hyperosmolality and hypernatraemia
0.027 0.973 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.973 0.027
W23.2 School, other institution and public administrative area
0.026 0.974 0.000
T50.1 Loop [high-ceiling] diuretics
0.000 0.974 0.026
E87.7 Fluid overload
0.026 0.974 0.000
T39.0 Salicylates
0.000 0.974 0.026
E79 Disorders of purine and pyrimidine metabolism
0.025 0.974 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.974 0.026
W45 Foreign body or object entering through skin
0.026 0.974 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.974 0.026
W34 Discharge from other and unspecified firearms
0.026 0.974 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.974 0.025
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.975 0.025
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.975 0.025
W44 Foreign body entering into or through eye or natural orifice
0.025 0.975 0.000
E85 Amyloidosis
0.025 0.975 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.025 0.975 0.000
E89.5 Postprocedural testicular hypofunction
0.025 0.975 0.000
W31 Contact with other and unspecified machinery
0.025 0.975 0.000
W29.9 Unspecified place
0.025 0.975 0.000
D37.1 Stomach
0.000 0.975 0.025
W23.7 Farm
0.024 0.975 0.000
W23.3 Sports and athletics area
0.024 0.976 0.000
W22 Striking against or struck by other objects
0.024 0.976 0.000
W21.9 Unspecified place
0.024 0.976 0.000
W49.8 Other specified place
0.024 0.976 0.000
W21.8 Other specified place
0.024 0.976 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.024 0.976 0.000
W21.0 Home
0.024 0.976 0.000
E74 Other disorders of carbohydrate metabolism
0.023 0.976 0.000
W49.6 Industrial and construction area
0.023 0.976 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.977 0.023
E89.4 Postprocedural ovarian failure
0.023 0.977 0.000
W40 Explosion of other materials
0.023 0.977 0.000
D32 Benign neoplasm of meninges
0.023 0.977 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.977 0.023
T40.8 Lysergide [LSD]
0.000 0.977 0.023
T40.7 Cannabis (derivatives)
0.000 0.977 0.023
T40.3 Methadone
0.000 0.977 0.023
T40.1 Heroin
0.000 0.977 0.023
T40.0 Opium
0.000 0.977 0.023
W45.6 Industrial and construction area
0.023 0.977 0.000
W46 Contact with hypodermic needle
0.023 0.977 0.000
W43 Exposure to vibration
0.023 0.977 0.000
W42 Exposure to noise
0.023 0.977 0.000
W41 Exposure to high-pressure jet
0.023 0.977 0.000
W39 Discharge of firework
0.023 0.977 0.000
W38 Explosion and rupture of other specified pressurised devices
0.023 0.977 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.023 0.977 0.000
W36 Explosion and rupture of gas cylinder
0.023 0.977 0.000
W35 Explosion and rupture of boiler
0.023 0.977 0.000
W33 Rifle, shotgun and larger firearm discharge
0.023 0.977 0.000
W32 Handgun discharge
0.023 0.977 0.000
W30 Contact with agricultural machinery
0.023 0.977 0.000
T40.5 Cocaine
0.000 0.977 0.023
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.977 0.023
W27 Contact with nonpowered hand tool
0.023 0.977 0.000
T36 Poisoning by systemic antibiotics
0.000 0.977 0.023
E75.2 Other sphingolipidosis
0.022 0.977 0.000
E84.9 Cystic fibrosis, unspecified
0.022 0.978 0.000
W23.9 Unspecified place
0.022 0.978 0.000
W23.8 Other specified place
0.022 0.978 0.000
W23.6 Industrial and construction area
0.022 0.978 0.000
W23.5 Trade and service area
0.022 0.978 0.000
W23.0 Home
0.022 0.978 0.000
W23.1 Residential institution
0.022 0.978 0.000
W28 Contact with powered lawn mower
0.022 0.978 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.022 0.978 0.000
T40.4 Other synthetic narcotics
0.000 0.978 0.022
W49.7 Farm
0.022 0.978 0.000
W49.5 Trade and service area
0.022 0.978 0.000
W49.4 Street and highway
0.022 0.978 0.000
W49.3 Sports and athletics area
0.022 0.978 0.000
W49.2 School, other institution and public administrative area
0.022 0.978 0.000
W49.1 Residential institution
0.022 0.978 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.022 0.978 0.000
E84.8 Cystic fibrosis with other manifestations
0.021 0.978 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.021 0.978 0.000
W26 Contact with knife, sword or dagger
0.022 0.978 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.021 0.978 0.000
W34.9 Unspecified place
0.021 0.978 0.000
W44.0 Home
0.021 0.978 0.000
E70.3 Albinism
0.021 0.979 0.000
E87.4 Mixed disorder of acid-base balance
0.021 0.979 0.000
T40.6 Other and unspecified narcotics
0.000 0.979 0.021
W21.3 Sports and athletics area
0.021 0.979 0.000
W21.7 Farm
0.021 0.979 0.000
W21.6 Industrial and construction area
0.021 0.979 0.000
W21.5 Trade and service area
0.021 0.979 0.000
W21.4 Street and highway
0.021 0.979 0.000
W21.2 School, other institution and public administrative area
0.021 0.979 0.000
W21.1 Residential institution
0.021 0.979 0.000
D37.7 Other digestive organs
0.000 0.979 0.021
E89.1 Postprocedural hypoinsulinaemia
0.021 0.979 0.000
T42.1 Iminostilbenes
0.000 0.979 0.021
W20 Struck by thrown, projected or falling object
0.021 0.979 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.979 0.021
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.020 0.979 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.020 0.979 0.000
E70.2 Disorders of tyrosine metabolism
0.020 0.979 0.000
E70.1 Other hyperphenylalaninaemias
0.020 0.979 0.000
E70.0 Classical phenylketonuria
0.020 0.979 0.000
E75.6 Lipid storage disorder, unspecified
0.020 0.980 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.020 0.980 0.000
E75.3 Sphingolipidosis, unspecified
0.020 0.980 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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