TreeWAS – Variant ID: rs4625554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E07.9 Disorder of thyroid, unspecified	0.000	0.633	0.367
E07 Other disorders of thyroid	0.000	0.776	0.224
E07.8 Other specified disorders of thyroid	0.000	0.807	0.193
E07.1 Dyshormogenetic goitre	0.000	0.839	0.161
E07.0 Hypersecretion of calcitonin	0.000	0.839	0.161
L40.9 Psoriasis, unspecified	0.000	0.968	0.032
E00-E07 Disorders of thyroid gland	0.000	0.981	0.019
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.984	0.016
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.986	0.014
E00 Congenital iodine-deficiency syndrome	0.000	0.986	0.014
C71.9 Brain, unspecified	0.000	0.986	0.014
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.987	0.013
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.987	0.013
E06 Thyroiditis	0.000	0.987	0.013
C71 Malignant neoplasm of brain	0.000	0.989	0.011
Z86.0 Personal history of other neoplasms	0.011	0.989	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.990	0.010
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.990	0.010
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.990	0.010
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.990	0.010
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.990	0.010
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.990	0.010
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.990	0.010
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.990	0.010
C71.1 Frontal lobe	0.000	0.990	0.010
C71.8 Overlapping lesion of brain	0.000	0.990	0.010
C71.0 Cerebrum, except lobes and ventricles	0.000	0.990	0.010
E05.8 Other thyrotoxicosis	0.000	0.990	0.010
E05.5 Thyroid crisis or storm	0.000	0.990	0.010
E05.4 Thyrotoxicosis factitia	0.000	0.990	0.010
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.990	0.010
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.990	0.010
E06.5 Other chronic thyroiditis	0.000	0.991	0.009
E06.4 Drug-induced thyroiditis	0.000	0.991	0.009
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.991	0.009
E06.0 Acute thyroiditis	0.000	0.991	0.009
E06.9 Thyroiditis, unspecified	0.000	0.991	0.009
E06.3 Autoimmune thyroiditis	0.000	0.991	0.009
E06.1 Subacute thyroiditis	0.000	0.992	0.008
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.008	0.992	0.000
C71.6 Cerebellum	0.000	0.992	0.008
C71.5 Cerebral ventricle	0.000	0.992	0.008
C71.3 Parietal lobe	0.000	0.992	0.008
C71.2 Temporal lobe	0.000	0.992	0.008
C71.7 Brain stem	0.000	0.992	0.007
C71.4 Occipital lobe	0.000	0.993	0.007
T81.8 Other complications of procedures, not elsewhere classified	0.006	0.994	0.000
G93.0 Cerebral cysts	0.000	0.994	0.006
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.995	0.005
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.005	0.995	0.000
M00.9 Pyogenic arthritis, unspecified	0.005	0.995	0.000
R85.7 Abnormal histological findings	0.005	0.995	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.005	0.995	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.995	0.000
G03.9 Meningitis, unspecified	0.005	0.995	0.000
E04 Other non-toxic goitre	0.000	0.995	0.005
E03 Other hypothyroidism	0.000	0.995	0.005
E05.9 Thyrotoxicosis, unspecified	0.000	0.995	0.005
K04.5 Chronic apical periodontitis	0.000	0.995	0.005
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.004	0.995	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
L40 Psoriasis	0.000	0.996	0.004
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.004	0.996	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.004	0.996	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.004	0.996	0.000
G03 Meningitis due to other and unspecified causes	0.004	0.996	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.004	0.996	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.004	0.996	0.000
M25.46 Effusion of joint (Lower leg)	0.004	0.996	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.004	0.996	0.000
R89.5 Abnormal microbiological findings	0.004	0.996	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.004	0.996	0.000
E04.8 Other specified non-toxic goitre	0.000	0.996	0.004
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.004	0.996	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.996	0.004
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.996	0.004
E03.5 Myxoedema coma	0.000	0.996	0.004
E03.4 Atrophy of thyroid (acquired)	0.000	0.996	0.004
E03.3 Postinfectious hypothyroidism	0.000	0.996	0.004
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.003	0.996	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.996	0.004
G04.0 Acute disseminated encephalitis	0.003	0.997	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.997	0.003
K04.8 Radicular cyst	0.000	0.997	0.003
E03.1 Congenital hypothyroidism without goitre	0.000	0.997	0.003
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.997	0.003
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
L40.4 Guttate psoriasis	0.000	0.997	0.003
L40.2 Acrodermatitis continua	0.000	0.997	0.003
S63.6 Sprain and strain of finger(s)	0.003	0.997	0.000
H02.4 Ptosis of eyelid	0.003	0.997	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.003	0.997	0.000
L40.8 Other psoriasis	0.000	0.997	0.003
D17 Benign lipomatous neoplasm	0.003	0.997	0.000
R86 Abnormal findings in specimens from male genital organs	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
E23.0 Hypopituitarism	0.000	0.997	0.003
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.003	0.997	0.000
G04.1 Tropical spastic paraplegia	0.003	0.997	0.000
L40.1 Generalised pustular psoriasis	0.000	0.997	0.003
L40.3 Pustulosis palmaris et plantaris	0.000	0.997	0.003
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.997	0.003
R89 Abnormal findings in specimens from other organs, systems and tissues	0.003	0.997	0.000
F43.2 Adjustment disorders	0.000	0.997	0.003
G93 Other disorders of brain	0.000	0.997	0.003
G03.8 Meningitis due to other specified causes	0.003	0.997	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.003	0.997	0.000
G03.1 Chronic meningitis	0.003	0.997	0.000
G03.0 Nonpyogenic meningitis	0.003	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.003
R86.6 Abnormal cytological findings	0.003	0.997	0.000
M00 Pyogenic arthritis	0.003	0.997	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.997	0.003
G93.5 Compression of brain	0.000	0.997	0.003
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.003	0.997	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.003	0.997	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.003	0.997	0.000
G93.2 Benign intracranial hypertension	0.000	0.997	0.003
R85.8 Other abnormal findings	0.003	0.997	0.000
R85.6 Abnormal cytological findings	0.003	0.997	0.000
R85.4 Abnormal immunological findings	0.003	0.997	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.997	0.000
R85.1 Abnormal level of hormones	0.003	0.997	0.000
R85.0 Abnormal level of enzymes	0.003	0.997	0.000
R86.9 Unspecified abnormal finding	0.003	0.997	0.000
G93.4 Encephalopathy, unspecified	0.000	0.997	0.003
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
C70 Malignant neoplasm of meninges	0.000	0.997	0.003
E03.8 Other specified hypothyroidism	0.000	0.997	0.003
R85.9 Unspecified abnormal finding	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.003	0.997	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.003	0.997	0.000
R86.7 Abnormal histological findings	0.003	0.997	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.003	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.003	0.997	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.003	0.997	0.000
R86.8 Other abnormal findings	0.003	0.997	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
R85.5 Abnormal microbiological findings	0.003	0.997	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.003	0.997	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.000	0.997	0.003
J30.4 Allergic rhinitis, unspecified	0.000	0.997	0.003
R86.5 Abnormal microbiological findings	0.003	0.997	0.000
R86.4 Abnormal immunological findings	0.003	0.997	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.997	0.000
R86.1 Abnormal level of hormones	0.003	0.997	0.000
R86.0 Abnormal level of enzymes	0.003	0.997	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.003	0.997	0.000
M90.7 Fracture of bone in neoplastic disease	0.003	0.997	0.000
R84.5 Abnormal microbiological findings	0.003	0.997	0.000
S00.0 Superficial injury of scalp	0.003	0.997	0.000
R89.9 Unspecified abnormal finding	0.002	0.997	0.000
R89.8 Other abnormal findings	0.002	0.997	0.000
R89.6 Abnormal cytological findings	0.002	0.997	0.000
R89.4 Abnormal immunological findings	0.002	0.997	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.997	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.997	0.000
R89.1 Abnormal level of hormones	0.002	0.997	0.000
R89.0 Abnormal level of enzymes	0.002	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.997	0.002
G35 Multiple sclerosis	0.003	0.997	0.000
C70.0 Cerebral meninges	0.000	0.997	0.002
M00.0 Staphylococcal arthritis and polyarthritis	0.002	0.997	0.000
G93.7 Reye's syndrome	0.000	0.997	0.002
K61.0 Anal abscess	0.003	0.997	0.000
N48.4 Impotence of organic origin	0.000	0.997	0.003
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.002	0.997	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.002	0.997	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.002	0.997	0.000
W07.0 Home	0.002	0.997	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
G06.0 Intracranial abscess and granuloma	0.002	0.998	0.000
R40.0 Somnolence	0.000	0.998	0.002
Z03.9 Observation for suspected disease or condition, unspecified	0.002	0.998	0.000
K76.6 Portal hypertension	0.000	0.998	0.002
G02.0 Meningitis in viral diseases classified elsewhere	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.000	0.998	0.002
C70.1 Spinal meninges	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.002	0.998	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.998	0.002
Z39.1 Care and examination of lactating mother	0.002	0.998	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G02.1 Meningitis in mycoses	0.002	0.998	0.000
R89.7 Abnormal histological findings	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
R84.9 Unspecified abnormal finding	0.002	0.998	0.000
R84.8 Other abnormal findings	0.002	0.998	0.000
R84.7 Abnormal histological findings	0.002	0.998	0.000
R84.6 Abnormal cytological findings	0.002	0.998	0.000
R84.4 Abnormal immunological findings	0.002	0.998	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R84.1 Abnormal level of hormones	0.002	0.998	0.000
R84.0 Abnormal level of enzymes	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
R83 Abnormal findings in cerebrospinal fluid	0.002	0.998	0.000
Z01.9 Special examination, unspecified	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
C18.1 Appendix	0.000	0.998	0.002
G06.1 Intraspinal abscess and granuloma	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
C72.9 Central nervous system, unspecified	0.000	0.998	0.002
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.998	0.002
C72.5 Other and unspecified cranial nerves	0.000	0.998	0.002
C72.4 Acoustic nerve	0.000	0.998	0.002
C72.3 Optic nerve	0.000	0.998	0.002
C72.2 Olfactory nerve	0.000	0.998	0.002
C72.1 Cauda equina	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.998	0.002
H54.7 Unspecified visual loss	0.000	0.998	0.002
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.002	0.998	0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
K04.0 Pulpitis	0.000	0.998	0.002
G06.2 Extradural and subdural abscess, unspecified	0.002	0.998	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
M00.19 Pneumococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.18 Pneumococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.17 Pneumococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.16 Pneumococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
M00.15 Pneumococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.14 Pneumococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.13 Pneumococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.12 Pneumococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.11 Pneumococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
M00.10 Pneumococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
M00.29 Other streptococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.28 Other streptococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.27 Other streptococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.26 Other streptococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
M00.25 Other streptococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.24 Other streptococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.23 Other streptococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.22 Other streptococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.21 Other streptococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
M00.20 Other streptococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
M00.89 Arthritis and polyarthritis due to other specified bacterial agents (Site unspecified)	0.002	0.998	0.000
M00.88 Arthritis and polyarthritis due to other specified bacterial agents (Other)	0.002	0.998	0.000
M00.87 Arthritis and polyarthritis due to other specified bacterial agents (Ankle and foot)	0.002	0.998	0.000
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.002	0.998	0.000
M00.85 Arthritis and polyarthritis due to other specified bacterial agents (Pelvic region and thigh)	0.002	0.998	0.000
M00.84 Arthritis and polyarthritis due to other specified bacterial agents (Hand)	0.002	0.998	0.000
M00.83 Arthritis and polyarthritis due to other specified bacterial agents (Forearm)	0.002	0.998	0.000
M00.82 Arthritis and polyarthritis due to other specified bacterial agents (Upper arm)	0.002	0.998	0.000
M00.81 Arthritis and polyarthritis due to other specified bacterial agents (Shoulder region)	0.002	0.998	0.000
M00.80 Arthritis and polyarthritis due to other specified bacterial agents (Multiple sites)	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
J30.0 Vasomotor rhinitis	0.000	0.998	0.002
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.998	0.000
C72.0 Spinal cord	0.000	0.998	0.002
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
D32.0 Cerebral meninges	0.000	0.998	0.002
K04.3 Abnormal hard tissue formation in pulp	0.000	0.998	0.002
K04.2 Pulp degeneration	0.000	0.998	0.002
K04.1 Necrosis of pulp	0.000	0.998	0.002
W07.8 Other specified place	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.998	0.002
L40.0 Psoriasis vulgaris	0.000	0.998	0.002
O43.8 Other placental disorders	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
W07 Fall involving chair	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
R83.9 Unspecified abnormal finding	0.002	0.998	0.000
R83.7 Abnormal histological findings	0.002	0.998	0.000
R83.6 Abnormal cytological findings	0.002	0.998	0.000
R83.5 Abnormal microbiological findings	0.002	0.998	0.000
R83.4 Abnormal immunological findings	0.002	0.998	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R83.1 Abnormal level of hormones	0.002	0.998	0.000
R83.0 Abnormal level of enzymes	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
S63.0 Dislocation of wrist	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
J10 Influenza due to identified influenza virus	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
J30.3 Other allergic rhinitis	0.000	0.998	0.002
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
G00.8 Other bacterial meningitis	0.002	0.998	0.000
G00.3 Staphylococcal meningitis	0.002	0.998	0.000
G00.2 Streptococcal meningitis	0.002	0.998	0.000
G00.0 Haemophilus meningitis	0.002	0.998	0.000
G93.6 Cerebral oedema	0.001	0.998	0.001
J30.2 Other seasonal allergic rhinitis	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
S63.1 Dislocation finger	0.002	0.998	0.000
S63.2 Multiple dislocations of fingers	0.002	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.000	0.998	0.002
S63.5 Sprain and strain of wrist	0.002	0.998	0.000
Z91.5 Personal history of self-harm	0.000	0.998	0.002
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
W07.1 Residential institution	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.000	0.998	0.002
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.998	0.002
Q70.3 Webbed toes	0.002	0.998	0.000
W07.9 Unspecified place	0.002	0.998	0.000
F60 Specific personality disorders	0.000	0.998	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
J15 Bacterial pneumonia, not elsewhere classified	0.002	0.998	0.000
M79.2 Neuralgia and neuritis, unspecified	0.002	0.998	0.000
I81 Portal vein thrombosis	0.000	0.998	0.002
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
R83.8 Other abnormal findings	0.001	0.998	0.000
W07.5 Trade and service area	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
W07.2 School, other institution and public administrative area	0.002	0.998	0.000
W07.7 Farm	0.002	0.998	0.000
W07.6 Industrial and construction area	0.002	0.998	0.000
W07.4 Street and highway	0.002	0.998	0.000
W07.3 Sports and athletics area	0.002	0.998	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.001	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.001
C69.6 Orbit	0.000	0.998	0.001
C69.5 Lachrymal gland and duct	0.000	0.998	0.001
C69.4 Ciliary body	0.000	0.998	0.001
C69.2 Retina	0.000	0.998	0.001
C69.1 Cornea	0.000	0.998	0.001
F43.0 Acute stress reaction	0.000	0.998	0.002
J10.8 Influenza with other manifestations, influenza virus identified	0.001	0.998	0.000
K70.4 Alcoholic hepatic failure	0.000	0.998	0.002
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.998	0.002
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.998	0.000
E23.2 Diabetes insipidus	0.000	0.998	0.001
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.998	0.002
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.4 Achondroplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
S29.9 Unspecified injury of thorax	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.998	0.000
Q78.6 Multiple congenital exostoses	0.001	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.998	0.000
Q78.4 Enchondromatosis	0.001	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.998	0.000
Q78.2 Osteopetrosis	0.001	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.001	0.998	0.000
C69.0 Conjunctiva	0.000	0.998	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.001
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
Q78.0 Osteogenesis imperfecta	0.001	0.998	0.000
F60.5 Anankastic personality disorder	0.000	0.998	0.001
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations