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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4637816
log Bayes Factor = 0.0835773
Chromosome 8   position 78,277,473  (GRCh37) Explore rs4637816 on Ensembl!
Variant rs4637816 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T39.1 4-Aminophenol derivatives
0.000 0.868 0.132
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.874 0.126
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.876 0.124
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.899 0.101
T39.0 Salicylates
0.000 0.902 0.098
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.909 0.091
T39.4 Antirheumatics, not elsewhere classified
0.000 0.909 0.091
T39.2 Pyrazolone derivatives
0.000 0.909 0.091
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.948 0.052
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.953 0.047
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.954 0.046
T42.4 Benzodiazepines
0.000 0.957 0.043
T40.2 Other opioids
0.000 0.958 0.042
T40.4 Other synthetic narcotics
0.000 0.962 0.038
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.962 0.037
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.962 0.037
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.962 0.037
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.962 0.037
Z96.6 Presence of orthopaedic joint implants
0.037 0.963 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.963 0.037
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.963 0.037
T36 Poisoning by systemic antibiotics
0.000 0.963 0.036
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.964 0.036
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.964 0.036
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.965 0.035
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.034 0.966 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.966 0.034
T40.8 Lysergide [LSD]
0.000 0.966 0.034
T40.7 Cannabis (derivatives)
0.000 0.966 0.034
T40.5 Cocaine
0.000 0.966 0.034
T40.3 Methadone
0.000 0.966 0.034
T40.1 Heroin
0.000 0.966 0.034
T40.0 Opium
0.000 0.966 0.034
T40.6 Other and unspecified narcotics
0.000 0.966 0.034
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.966 0.033
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.966 0.033
T42.3 Barbiturates
0.000 0.966 0.033
T42.2 Succinimides and oxazolidinediones
0.000 0.966 0.033
T42.0 Hydantoin derivatives
0.000 0.966 0.033
T42.1 Iminostilbenes
0.000 0.967 0.033
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.968 0.031
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.971 0.029
T45.0 Antiallergic and antiemetic drugs
0.000 0.971 0.029
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.972 0.028
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.973 0.027
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.973 0.027
T37.5 Antiviral drugs
0.000 0.973 0.027
T37.4 Anthelminthics
0.000 0.973 0.027
T37.3 Other antiprotozoal drugs
0.000 0.973 0.027
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.973 0.027
T37.1 Antimycobacterial drugs
0.000 0.973 0.027
T37.0 Sulphonamides
0.000 0.973 0.027
T41.5 Therapeutic gases
0.000 0.973 0.027
T41.4 Anaesthetic, unspecified
0.000 0.973 0.027
T41.3 Local anaesthetics
0.000 0.973 0.027
T41.2 Other and unspecified general anaesthetics
0.000 0.973 0.027
T41.1 Intravenous anaesthetics
0.000 0.973 0.027
T41.0 Inhaled anaesthetics
0.000 0.973 0.027
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.973 0.027
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.973 0.027
T48.5 Anti-common-cold drugs
0.000 0.973 0.027
T48.4 Expectorants
0.000 0.973 0.027
T48.3 Antitussives
0.000 0.973 0.027
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.973 0.027
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.973 0.027
T48.0 Oxytocic drugs
0.000 0.973 0.027
T49.9 Topical agent, unspecified
0.000 0.973 0.027
T49.8 Other topical agents
0.000 0.973 0.027
T49.7 Dental drugs, topically applied
0.000 0.973 0.027
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.973 0.027
T49.5 Ophthalmological drugs and preparations
0.000 0.973 0.027
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.973 0.027
T49.3 Emollients, demulcents and protectants
0.000 0.973 0.027
T49.2 Local astringents and local detergents
0.000 0.973 0.027
T49.1 Antipruritics
0.000 0.973 0.027
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.973 0.027
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.973 0.026
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.973 0.026
T47.7 Emetics
0.000 0.973 0.026
T47.6 Antidiarrhoeal drugs
0.000 0.973 0.026
T47.5 Digestants
0.000 0.973 0.026
T47.4 Other laxatives
0.000 0.973 0.026
T47.3 Saline and osmotic laxatives
0.000 0.973 0.026
T47.2 Stimulant laxatives
0.000 0.973 0.026
T47.0 Histamine H(2)-receptor antagonists
0.000 0.973 0.026
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.973 0.026
T45.8 Other primarily systemic and haematological agents
0.000 0.973 0.026
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.973 0.026
T45.6 Fibrinolysis-affecting drugs
0.000 0.973 0.026
T45.4 Iron and its compounds
0.000 0.973 0.026
T45.3 Enzymes, not elsewhere classified
0.000 0.973 0.026
T45.2 Vitamins, not elsewhere classified
0.000 0.973 0.026
T36.9 Systemic antibiotic, unspecified
0.000 0.973 0.026
T36.8 Other systemic antibiotics
0.000 0.973 0.026
T36.7 Antifungal antibiotics, systemically used
0.000 0.973 0.026
T36.6 Rifamycins
0.000 0.973 0.026
T36.5 Aminoglycosides
0.000 0.973 0.026
T36.4 Tetracyclines
0.000 0.973 0.026
T36.3 Macrolides
0.000 0.973 0.026
T36.2 Chloramphenicol group
0.000 0.973 0.026
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.973 0.026
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.974 0.026
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.974 0.026
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.974 0.026
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.974 0.026
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.974 0.026
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.974 0.026
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.974 0.026
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.974 0.026
T44.0 Anticholinesterase agents
0.000 0.974 0.026
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.974 0.026
T36.0 Penicillins
0.000 0.974 0.025
M23.3 Other meniscus derangements
0.025 0.975 0.000
T50.8 Diagnostic agents
0.000 0.975 0.025
T50.7 Analeptics and opioid receptor antagonists
0.000 0.975 0.025
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.975 0.025
T50.5 Appetite depressants
0.000 0.975 0.025
T50.4 Drugs affecting uric acid metabolism
0.000 0.975 0.025
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.975 0.025
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.975 0.025
T50.1 Loop [high-ceiling] diuretics
0.000 0.975 0.025
T50.0 Mineralocorticoids and their antagonists
0.000 0.975 0.025
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.975 0.025
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.975 0.024
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.024 0.976 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.024 0.976 0.000
T45.5 Anticoagulants
0.000 0.976 0.024
D25.1 Intramural leiomyoma of uterus
0.000 0.977 0.023
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.977 0.023
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.977 0.023
T46.7 Peripheral vasodilators
0.000 0.977 0.023
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.977 0.023
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.977 0.023
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.977 0.023
T46.1 Calcium-channel blockers
0.000 0.977 0.023
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.977 0.023
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.977 0.023
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.978 0.022
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.978 0.022
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.021 0.979 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.979 0.020
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.979 0.020
T38.7 Androgens and anabolic congeners
0.000 0.979 0.020
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.979 0.020
T38.5 Other oestrogens and progestogens
0.000 0.979 0.020
T38.4 Oral contraceptives
0.000 0.979 0.020
T38.2 Antithyroid drugs
0.000 0.979 0.020
T38.0 Glucocorticoids and synthetic analogues
0.000 0.979 0.020
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.020 0.980 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.019 0.981 0.000
K52 Other non-infective gastro-enteritis and colitis
0.019 0.981 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.019 0.981 0.000
M23.37 Other meniscus derangements-Capsular lig
0.018 0.982 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.982 0.018
T38.1 Thyroid hormones and substitutes
0.000 0.982 0.018
T43.9 Psychotropic drug, unspecified
0.000 0.984 0.016
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.984 0.016
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.984 0.016
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.984 0.016
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.984 0.016
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.001 0.985 0.015
K52.0 Gastro-enteritis and colitis due to radiation
0.015 0.985 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.015 0.985 0.000
T43.2 Other and unspecified antidepressants
0.000 0.985 0.015
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.014 0.986 0.000
T43.6 Psychostimulants with abuse potential
0.000 0.986 0.014
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.014 0.986 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.014 0.986 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.986 0.013
K52.1 Toxic gastro-enteritis and colitis
0.013 0.986 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.013 0.987 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.987 0.012
M17.9 Gonarthrosis, unspecified
0.012 0.988 0.000
M23 Internal derangement of knee
0.012 0.988 0.000
R47.0 Dysphasia and aphasia
0.012 0.988 0.000
K81.0 Acute cholecystitis
0.012 0.988 0.000
M24 Other specific joint derangements
0.011 0.989 0.000
M24.1 Other articular cartilage disorders
0.011 0.989 0.000
M24.5 Contracture of joint
0.011 0.989 0.000
M17 Gonarthrosis [arthrosis of knee]
0.011 0.989 0.000
M21.1 Varus deformity, not elsewhere classified
0.010 0.989 0.000
K52.3 Indeterminate colitis
0.010 0.989 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.010 0.990 0.000
M21 Other acquired deformities of limbs
0.010 0.990 0.000
M20-M25 Other joint disorders
0.010 0.990 0.000
M17.3 Other posttraumatic gonarthrosis
0.010 0.990 0.000
M24.57 Contracture of joint (Ankle and foot)
0.010 0.990 0.000
M23.0 Cystic meniscus
0.009 0.990 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.009 0.991 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.009 0.991 0.000
M23.1 Discoid meniscus (congenital)
0.009 0.991 0.000
M47.86 Other spondylosis (Lumbar region)
0.009 0.991 0.000
M23.4 Loose body in knee
0.009 0.991 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.009 0.991 0.000
M23.9 Internal derangement of knee, unspecified
0.009 0.991 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.009 0.991 0.000
K29.6 Other gastritis
0.009 0.991 0.000
M17.5 Other secondary gonarthrosis
0.009 0.991 0.000
M24.51 Contracture of joint (Shoulder region)
0.009 0.991 0.000
M81.9 Osteoporosis, unspecified
0.009 0.991 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.008 0.991 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.008 0.991 0.000
M21.6 Other acquired deformities of ankle and foot
0.008 0.992 0.000
M21.2 Flexion deformity
0.008 0.992 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.008 0.992 0.000
M24.6 Ankylosis of joint
0.008 0.992 0.000
M47.8 Other spondylosis
0.008 0.992 0.000
M24.2 Disorder of ligament
0.008 0.992 0.000
M24.9 Joint derangement, unspecified
0.008 0.992 0.000
M24.7 Protrusio acetabuli
0.008 0.992 0.000
M30 Polyarteritis nodosa and related conditions
0.008 0.992 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.008 0.992 0.000
M24.18 Other articular cartilage disorders (Other)
0.008 0.992 0.000
M24.14 Other articular cartilage disorders (Hand)
0.008 0.992 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.008 0.992 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.008 0.992 0.000
M81 Osteoporosis without pathological fracture
0.008 0.992 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.008 0.992 0.000
M47.89 Other spondylosis (Site unspecified)
0.008 0.992 0.000
M24.59 Contracture of joint (Site unspecified)
0.008 0.992 0.000
M24.58 Contracture of joint (Other)
0.008 0.992 0.000
M24.56 Contracture of joint (Lower leg)
0.008 0.992 0.000
M24.53 Contracture of joint (Forearm)
0.008 0.992 0.000
M24.52 Contracture of joint (Upper arm)
0.008 0.992 0.000
M24.50 Contracture of joint (Multiple sites)
0.008 0.992 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.008 0.992 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.008 0.992 0.000
M33 Dermatopolymyositis
0.008 0.992 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.008 0.992 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.008 0.992 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.008 0.992 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.008 0.992 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.008 0.992 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.008 0.992 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.008 0.992 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.008 0.992 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.008 0.992 0.000
K29.8 Duodenitis
0.008 0.992 0.000
M86-M90 Other osteopathies
0.008 0.992 0.000
M21.0 Valgus deformity, not elsewhere classified
0.008 0.992 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.008 0.992 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.008 0.992 0.000
M21.9 Acquired deformity of limb, unspecified
0.008 0.992 0.000
M21.8 Other specified acquired deformities of limbs
0.008 0.992 0.000
M21.7 Unequal limb length (acquired)
0.008 0.992 0.000
M21.3 Wrist or foot drop (acquired)
0.008 0.992 0.000
M17.1 Other primary gonarthrosis
0.008 0.992 0.000
M32 Systemic lupus erythematosus
0.008 0.992 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.007 0.992 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.008 0.992 0.000
M35 Other systemic involvement of connective tissue
0.007 0.993 0.000
M23.5 Chronic instability of knee
0.007 0.993 0.000
M89 Other disorders of bone
0.007 0.993 0.000
M23.49 Loose body in knee-Unspec lig/men
0.007 0.993 0.000
K29 Gastritis and duodenitis
0.007 0.993 0.000
M15-M19 Arthrosis
0.007 0.993 0.000
M21.4 Flat foot [pes planus] (acquired)
0.007 0.993 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.007 0.993 0.000
M45-M49 Spondylopathies
0.007 0.993 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.007 0.993 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.007 0.993 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.007 0.993 0.000
M23.07 Cystic meniscus-Capsular lig
0.007 0.993 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.007 0.993 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.007 0.993 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.007 0.993 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.007 0.993 0.000
M23.00 Cystic meniscus (Multiple sites)
0.007 0.993 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.007 0.993 0.000
K29.4 Chronic atrophic gastritis
0.007 0.993 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.007 0.993 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.007 0.993 0.000
M47 Spondylosis
0.007 0.993 0.000
M30.0 Polyarteritis nodosa
0.007 0.993 0.000
K29.5 Chronic gastritis, unspecified
0.007 0.993 0.000
M81.4 Drug-induced osteoporosis
0.007 0.993 0.000
M21.26 Flexion deformity (Lower leg)
0.007 0.993 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.007 0.993 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.007 0.993 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.007 0.993 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.007 0.993 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.007 0.993 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.007 0.993 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.007 0.993 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.007 0.993 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.007 0.993 0.000
M34 Systemic sclerosis
0.007 0.993 0.000
M80-M85 Disorders of bone density and structure
0.007 0.993 0.000
M24.54 Contracture of joint (Hand)
0.007 0.993 0.000
M23.47 Loose body in knee-Capsular lig
0.007 0.993 0.000
M23.46 Loose body in knee-O/unsp lat men
0.007 0.993 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.007 0.993 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.007 0.993 0.000
M23.43 Loose body in knee-Med lig/oth men
0.007 0.993 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.007 0.993 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.007 0.993 0.000
M23.40 Loose body in knee-Mult sites
0.007 0.993 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.007 0.993 0.000
M87 Osteonecrosis
0.007 0.993 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.007 0.993 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.007 0.993 0.000
M89.8 Other specified disorders of bone
0.007 0.993 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.007 0.993 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.007 0.993 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.007 0.993 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.007 0.993 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.007 0.993 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.007 0.993 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.007 0.993 0.000
M86 Osteomyelitis
0.007 0.993 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.006 0.993 0.001
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.007 0.993 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.007 0.993 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.007 0.993 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.007 0.993 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.007 0.993 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.007 0.993 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.007 0.993 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.007 0.993 0.000
M24.0 Loose body in joint
0.006 0.993 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.006 0.993 0.000
M21.24 Flexion deformity (Hand)
0.006 0.993 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.006 0.993 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.006 0.993 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.006 0.993 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.006 0.993 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.006 0.993 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.006 0.994 0.000
M17.0 Primary gonarthrosis, bilateral
0.006 0.994 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.006 0.994 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.006 0.994 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.006 0.994 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.006 0.994 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.006 0.994 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.006 0.994 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.006 0.994 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.006 0.994 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.006 0.994 0.000
M24.23 Disorder of ligament (Forearm)
0.006 0.994 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.006 0.994 0.000
M45 Ankylosing spondylitis
0.006 0.994 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.006 0.994 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.006 0.994 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.006 0.994 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.006 0.994 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.006 0.994 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.006 0.994 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.006 0.994 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.006 0.994 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.006 0.994 0.000
M21.29 Flexion deformity (Site unspecified)
0.006 0.994 0.000
M21.28 Flexion deformity (Other)
0.006 0.994 0.000
M21.27 Flexion deformity (Ankle and foot)
0.006 0.994 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.006 0.994 0.000
M21.23 Flexion deformity (Forearm)
0.006 0.994 0.000
M21.22 Flexion deformity (Upper arm)
0.006 0.994 0.000
M21.21 Flexion deformity (Shoulder region)
0.006 0.994 0.000
M21.20 Flexion deformity (Multiple sites)
0.006 0.994 0.000
M35.0 Sicca syndrome [Sjogren]
0.006 0.994 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.006 0.994 0.000
M36.3 Arthropathy in other blood disorders
0.006 0.994 0.000
M36.2 Haemophilic arthropathy
0.006 0.994 0.000
M36.1 Arthropathy in neoplastic disease
0.006 0.994 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.006 0.994 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.006 0.994 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.006 0.994 0.000
M24.24 Disorder of ligament (Hand)
0.006 0.994 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.006 0.994 0.000
M24.68 Ankylosis of joint (Other)
0.006 0.994 0.000
M24.66 Ankylosis of joint (Lower leg)
0.006 0.994 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.006 0.994 0.000
M24.64 Ankylosis of joint (Hand)
0.006 0.994 0.000
M24.63 Ankylosis of joint (Forearm)
0.006 0.994 0.000
M24.62 Ankylosis of joint (Upper arm)
0.006 0.994 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.006 0.994 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.006 0.994 0.000
M33.1 Other dermatomyositis
0.006 0.994 0.000
M24.29 Disorder of ligament (Site unspecified)
0.006 0.994 0.000
M24.28 Disorder of ligament (Other)
0.006 0.994 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.006 0.994 0.000
M24.22 Disorder of ligament (Upper arm)
0.006 0.994 0.000
M24.21 Disorder of ligament (Shoulder region)
0.006 0.994 0.000
M24.20 Disorder of ligament (Multiple sites)
0.006 0.994 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.006 0.994 0.000
M47.84 Other spondylosis (Thoracic region)
0.006 0.994 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.006 0.994 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.006 0.994 0.000
M35.1 Other overlap syndromes
0.006 0.994 0.000
J32.8 Other chronic sinusitis
0.006 0.994 0.000
M00-M03 Infectious arthropathies
0.006 0.994 0.000
M24.79 Protrusio acetabuli-Site unspec
0.006 0.994 0.000
M24.78 Protrusio acetabuli-Other
0.006 0.994 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.006 0.994 0.000
M24.76 Protrusio acetabuli-Lower leg
0.006 0.994 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.006 0.994 0.000
M24.74 Protrusio acetabuli-Hand
0.006 0.994 0.000
M24.73 Protrusio acetabuli-Forearm
0.006 0.994 0.000
M24.72 Protrusio acetabuli-Upper arm
0.006 0.994 0.000
M24.71 Protrusio acetabuli-Shldr region
0.006 0.994 0.000
M24.70 Protrusio acetabuli-Mult sites
0.006 0.994 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.006 0.994 0.000
M24.98 Joint derangement, unspecified (Other)
0.006 0.994 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.006 0.994 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.006 0.994 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M24.94 Joint derangement, unspecified (Hand)
0.006 0.994 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.006 0.994 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.006 0.994 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.006 0.994 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.006 0.994 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.006 0.994 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.006 0.994 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.006 0.994 0.000
M30.2 Juvenile polyarteritis
0.006 0.994 0.000
M47.1 Other spondylosis with myelopathy
0.006 0.994 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M81.2 Osteoporosis of disuse
0.006 0.994 0.000
M81.8 Other osteoporosis
0.006 0.994 0.000
M81.6 Localised osteoporosis [Lequesne]
0.006 0.994 0.000
M81.5 Idiopathic osteoporosis
0.006 0.994 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.006 0.994 0.000
M81.1 Postoophorectomy osteoporosis
0.006 0.994 0.000
M81.0 Postmenopausal osteoporosis
0.006 0.994 0.000
M33.9 Dermatopolymyositis, unspecified
0.006 0.994 0.000
M33.2 Polymyositis
0.006 0.994 0.000
M33.0 Juvenile dermatomyositis
0.006 0.994 0.000
R06.8 Other and unspecified abnormalities of breathing
0.006 0.994 0.000
M90 Osteopathies in diseases classified elsewhere
0.006 0.994 0.000
M87.9 Osteonecrosis, unspecified
0.006 0.994 0.000
J32.9 Chronic sinusitis, unspecified
0.006 0.994 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.005 0.994 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.006 0.994 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.006 0.994 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.006 0.994 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.006 0.994 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.006 0.994 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.006 0.994 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.006 0.994 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.006 0.994 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.006 0.994 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.006 0.994 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.006 0.994 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.006 0.994 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.006 0.994 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.006 0.994 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.006 0.994 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.006 0.994 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.006 0.994 0.000
M21.79 Unequal limb length (acquired) (Site unspecified)
0.006 0.994 0.000
M21.78 Unequal limb length (acquired)-Other
0.006 0.994 0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)
0.006 0.994 0.000
M21.76 Unequal limb length (acquired) (Lower leg)
0.006 0.994 0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.006 0.994 0.000
M21.74 Unequal limb length (acquired) (Hand)
0.006 0.994 0.000
M21.73 Unequal limb length (acquired) (Forearm)
0.006 0.994 0.000
M21.72 Unequal limb length (acquired) (Upper arm)
0.006 0.994 0.000
M21.71 Unequal limb length (acquired)-Shldr region
0.006 0.994 0.000
M21.70 Unequal limb length (acquired) (Multiple sites)
0.006 0.994 0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)
0.006 0.994 0.000
M21.88 Other specified acquired deformities of limbs-Other
0.006 0.994 0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.006 0.994 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.006 0.994 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.006 0.994 0.000
M21.84 Other specified acquired deformities of limbs (Hand)
0.006 0.994 0.000
M21.83 Other specified acquired deformities of limbs (Forearm)
0.006 0.994 0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)
0.006 0.994 0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)
0.006 0.994 0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)
0.006 0.994 0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)
0.006 0.994 0.000
M21.98 Acquired deformity of limb, unspecified-Other
0.006 0.994 0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)
0.006 0.994 0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)
0.006 0.994 0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M21.94 Acquired deformity of limb, unspecified (Hand)
0.006 0.994 0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)
0.006 0.994 0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)
0.006 0.994 0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)
0.006 0.994 0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)
0.006 0.994 0.000
M10.99 Gout, unspecified (Site unspecified)
0.006 0.994 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.006 0.994 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.006 0.994 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.006 0.994 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.006 0.994 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.006 0.994 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.006 0.994 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.006 0.994 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.006 0.994 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.006 0.994 0.000
M31 Other necrotising vasculopathies
0.006 0.994 0.000
M22 Disorders of patella
0.006 0.994 0.000
M89.5 Osteolysis
0.006 0.994 0.000
M89.0 Algoneurodystrophy
0.006 0.994 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.006 0.994 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.006 0.994 0.000
M32.8 Other forms of systemic lupus erythematosus
0.006 0.994 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.006 0.994 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.006 0.994 0.000
M86.6 Other chronic osteomyelitis
0.006 0.994 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.005 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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