TreeWAS – Variant ID: rs4638289

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86.0 Sarcoidosis of lung	0.016	0.984	0.000
D86.9 Sarcoidosis, unspecified	0.015	0.985	0.000
D86 Sarcoidosis	0.015	0.985	0.000
D86.3 Sarcoidosis of skin	0.013	0.987	0.000
K11.2 Sialoadenitis	0.012	0.988	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.988	0.012
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.011	0.989	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.989	0.011
D86.1 Sarcoidosis of lymph nodes	0.010	0.990	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.009	0.991	0.000
G57.6 Lesion of plantar nerve	0.000	0.991	0.009
D86.8 Sarcoidosis of other and combined sites	0.008	0.992	0.000
E27 Other disorders of adrenal gland	0.000	0.992	0.008
E27.2 Addisonian crisis	0.000	0.993	0.007
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.994	0.006
L03.0 Cellulitis of finger and toe	0.006	0.994	0.000
R63.0 Anorexia	0.006	0.994	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.994	0.006
R07.0 Pain in throat	0.000	0.994	0.006
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.006
E27.0 Other adrenocortical overactivity	0.000	0.994	0.006
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.994	0.006
S82.00 Fracture of patella (closed)	0.000	0.994	0.006
Z39.0 Care and examination immediately after delivery	0.005	0.995	0.000
D83 Common variable immunodeficiency	0.005	0.995	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.995	0.005
D84 Other immunodeficiencies	0.005	0.995	0.000
Z39.1 Care and examination of lactating mother	0.005	0.995	0.000
Z00.0 General medical examination	0.000	0.995	0.005
Z93.3 Colostomy status	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.005
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.004	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.995	0.000
D83.9 Common variable immunodeficiency, unspecified	0.004	0.996	0.000
Z39 Postpartum care and examination	0.004	0.996	0.000
I84.9 Unspecified haemorrhoids without complication	0.000	0.996	0.004
D83.8 Other common variable immunodeficiencies	0.004	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.004	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.004	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.004	0.996	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.996	0.004
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.996	0.004
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.996	0.004
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.996	0.004
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.996	0.004
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.996	0.004
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.996	0.004
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.996	0.004
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D84.1 Defects in the complement system	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.996	0.000
M21.3 Wrist or foot drop (acquired)	0.004	0.996	0.000
D82.1 Di George's syndrome	0.003	0.996	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.996	0.004
D81.9 Combined immunodeficiency, unspecified	0.003	0.996	0.000
D81.8 Other combined immunodeficiencies	0.003	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.996	0.000
D81.4 Nezelof's syndrome	0.003	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.996	0.000
D84.8 Other specified immunodeficiencies	0.003	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.996	0.003
I84.1 Internal haemorrhoids with other complications	0.000	0.996	0.004
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.997	0.003
Z39.2 Routine postpartum follow-up	0.003	0.997	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.997	0.003
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.997	0.003
Z00.8 Other general examinations	0.000	0.997	0.003
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.997	0.003
S82.0 Fracture of patella	0.000	0.997	0.003
M21.33 Wrist or foot drop (acquired) (Forearm)	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.000	0.997	0.003
M67.1 Other contracture of tendon (sheath)	0.000	0.997	0.003
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
G57 Mononeuropathies of lower limb	0.000	0.997	0.003
M21.39 Wrist or foot drop (acquired)-Site unspec	0.003	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.003	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.003	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.003	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.003	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.003	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
E34 Other endocrine disorders	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
Z00.3 Examination for adolescent development state	0.000	0.997	0.003
Z00.2 Examination for period of rapid growth in childhood	0.000	0.997	0.003
Z00.1 Routine child health examination	0.000	0.997	0.003
G57.5 Tarsal tunnel syndrome	0.000	0.997	0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
C38.4 Pleura	0.000	0.997	0.003
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
S82.01 Fracture of patella (open)	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
K04.6 Periapical abscess with sinus	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.997	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
T91.3 Sequelae of injury of spinal cord	0.000	0.997	0.003
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
R03.1 Nonspecific low blood-pressure reading	0.003	0.997	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.997	0.002
E24 Cushing's syndrome	0.000	0.997	0.003
E26 Hyperaldosteronism	0.000	0.997	0.002
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
G57.3 Lesion of lateral popliteal nerve	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.000	0.998	0.002
G57.4 Lesion of medial popliteal nerve	0.000	0.998	0.002
G57.2 Lesion of femoral nerve	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.000	0.998	0.002
G57.0 Lesion of sciatic nerve	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
N21.0 Calculus in bladder	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
Z53.9 Procedure not carried out, unspecified reason	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.998	0.002
E10.4 With neurological complications	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
K38.1 Appendicular concretions	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
Z90.8 Acquired absence of other organs	0.002	0.998	0.000
E32 Diseases of thymus	0.000	0.998	0.002
M67 Other disorders of synovium and tendon	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
E78.8 Other disorders of lipoprotein metabolism	0.000	0.998	0.002
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.002
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
M53 Other dorsopathies, not elsewhere classified	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
C34 Malignant neoplasm of bronchus and lung	0.000	0.998	0.002
E29 Testicular dysfunction	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
G57.1 Meralgia paraesthetica	0.000	0.998	0.002
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
M53.9 Dorsopathy, unspecified	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
M67.0 Short Achilles tendon (acquired)	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
C38.3 Mediastinum, part unspecified	0.000	0.998	0.002
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.998	0.002
C38.2 Posterior mediastinum	0.000	0.998	0.002
C38.1 Anterior mediastinum	0.000	0.998	0.002
C38.0 Heart	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.998	0.002
M67.3 Transient synovitis	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
R23.4 Changes in skin texture	0.000	0.998	0.002
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.000	0.998	0.002
C34.0 Main bronchus	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
M53.1 Cervicobrachial syndrome	0.000	0.998	0.002
M53.0 Cervicocranial syndrome	0.000	0.998	0.002
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
T50.8 Diagnostic agents	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
K51.2 Ulcerative (chronic) proctitis	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.002
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.002
T91.1 Sequelae of fracture of spine	0.000	0.998	0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
N39.9 Disorder of urinary system, unspecified	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.000	0.998	0.001
E29.0 Testicular hyperfunction	0.000	0.998	0.001
E32.9 Disease of thymus, unspecified	0.000	0.998	0.001
K43.0 Ventral hernia with obstruction, without gangrene	0.002	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.998	0.002
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.000	0.998	0.001
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.001
M53.94 Dorsopathy, unspecified (Thoracic region)	0.000	0.998	0.001
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.001
M53.92 Dorsopathy, unspecified (Cervical region)	0.000	0.998	0.001
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.001
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.001
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.001
K51.5 Mucosal proctocolitis	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.001
E28.8 Other ovarian dysfunction	0.000	0.998	0.001
E28.1 Androgen excess	0.000	0.998	0.001
E28.0 Oestrogen excess	0.000	0.998	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.001
K57.2 Diverticular disease of large intestine with perforation and abscess	0.002	0.998	0.000
M53.2 Spinal instabilities	0.000	0.998	0.001
C34.8 Overlapping lesion of bronchus and lung	0.000	0.998	0.001
E20.8 Other hypoparathyroidism	0.000	0.998	0.001
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.001
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
M53.8 Other specified dorsopathies	0.000	0.998	0.001
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.998	0.001
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.001
T50.5 Appetite depressants	0.000	0.998	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.001
T88.4 Failed or difficult intubation	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.001
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.998	0.002
M24.56 Contracture of joint (Lower leg)	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.001
M53.09 Cervicocranial syndrome-Site unspe	0.000	0.998	0.001
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.000	0.998	0.001
M53.07 Cervicocranial syndrome-Lumbosacral	0.000	0.998	0.001
M53.06 Cervicocranial syndrome-Lumbar	0.000	0.998	0.001
M53.05 Cervicocranial syndrome-Thoracolumbar	0.000	0.998	0.001
M53.04 Cervicocranial syndrome-Thoracic	0.000	0.998	0.001
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.000	0.998	0.001
M53.02 Cervicocranial syndrome (Cervical region)	0.000	0.998	0.001
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.000	0.998	0.001
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.000	0.998	0.001
M53.19 Cervicobrachial syndrome-Site unspe	0.000	0.998	0.001
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.000	0.998	0.001
M53.17 Cervicobrachial syndrome-Lumbosacral	0.000	0.998	0.001
M53.16 Cervicobrachial syndrome-Lumbar	0.000	0.998	0.001
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.000	0.998	0.001
M53.14 Cervicobrachial syndrome-Thoracic	0.000	0.998	0.001
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.000	0.998	0.001
M53.12 Cervicobrachial syndrome (Cervical region)	0.000	0.998	0.001
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.000	0.998	0.001
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.000	0.998	0.001
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.001
G44.0 Cluster headache syndrome	0.000	0.998	0.002
H83.0 Labyrinthitis	0.002	0.998	0.000
M67.4 Ganglion	0.000	0.998	0.001
G04.0 Acute disseminated encephalitis	0.001	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.001	0.998	0.000
T09.0 Superficial injury of trunk, level unspecified	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
C31 Malignant neoplasm of accessory sinuses	0.000	0.998	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
C31.0 Maxillary sinus	0.000	0.998	0.001
G30 Alzheimer's disease	0.001	0.998	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.000	0.999	0.001
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.999	0.001
J01.0 Acute maxillary sinusitis	0.001	0.999	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.001	0.999	0.000
C37 Malignant neoplasm of thymus	0.000	0.999	0.001
M24.54 Contracture of joint (Hand)	0.000	0.999	0.001
E21.3 Hyperparathyroidism, unspecified	0.000	0.999	0.001
R23.2 Flushing	0.000	0.999	0.001
M53.29 Spinal instabilities (Site unspecified)	0.000	0.999	0.001
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M53.25 Spinal instabilities (Thoracolumbar region)	0.000	0.999	0.001
M53.24 Spinal instabilities (Thoracic region)	0.000	0.999	0.001
M53.23 Spinal instabilities (Cervicothoracic region)	0.000	0.999	0.001
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.20 Spinal instabilities (Multiple sites in spine)	0.000	0.999	0.001
C80.9 Malignant neoplasm, unspecified	0.001	0.999	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.001	0.999	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.999	0.001
B91 Sequelae of poliomyelitis	0.001	0.999	0.000
G97.8 Other postprocedural disorders of nervous system	0.001	0.999	0.000
J01.2 Acute ethmoidal sinusitis	0.001	0.999	0.000
W55.0 Home	0.000	0.999	0.001
Y84.6 Urinary catheterisation	0.000	0.999	0.001
J01 Acute sinusitis	0.001	0.999	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.999	0.001
M53.89 Other specified dorsopathies (Site unspecified)	0.000	0.999	0.001
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M53.87 Other specified dorsopathies (Lumbosacral region)	0.000	0.999	0.001
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.000	0.999	0.001
M53.84 Other specified dorsopathies (Thoracic region)	0.000	0.999	0.001
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.000	0.999	0.001
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.000	0.999	0.001
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.000	0.999	0.001
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
M22.4 Chondromalacia patellae	0.001	0.999	0.000
D13.5 Extrahepatic bile ducts	0.001	0.999	0.000
G04.1 Tropical spastic paraplegia	0.001	0.999	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.001	0.999	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.999	0.001
M67.49 Ganglion, multiple sites	0.000	0.999	0.001
M67.45 Ganglion, hip	0.000	0.999	0.001
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.999	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
Z88.2 Personal history of allergy to sulphonamides	0.001	0.999	0.000
C31.9 Accessory sinus, unspecified	0.000	0.999	0.001
C31.8 Overlapping lesion of accessory sinuses	0.000	0.999	0.001
C31.3 Sphenoidal sinus	0.000	0.999	0.001
C31.2 Frontal sinus	0.000	0.999	0.001
C31.1 Ethmoidal sinus	0.000	0.999	0.001
C32.0 Glottis	0.000	0.999	0.001
G57.8 Other mononeuropathies of lower limb	0.000	0.999	0.001
M53.22 Spinal instabilities (Cervical region)	0.000	0.999	0.001
M53.86 Other specified dorsopathies (Lumbar region)	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.000	0.999	0.001
R30.9 Painful micturition, unspecified	0.000	0.999	0.001
T40.6 Other and unspecified narcotics	0.000	0.999	0.001
C33 Malignant neoplasm of trachea	0.000	0.999	0.001
O40 Polyhydramnios	0.000	0.999	0.001
M53.26 Spinal instabilities (Lumbar region)	0.000	0.999	0.001
C78.4 Secondary malignant neoplasm of small intestine	0.001	0.999	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.999	0.001
G30.1 Alzheimer's disease with late onset	0.001	0.999	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.999	0.001
M67.47 Ganglion, ankle and foot	0.000	0.999	0.001
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
J01.1 Acute frontal sinusitis	0.001	0.999	0.000
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.000	0.999	0.001
C26.0 Intestinal tract, part unspecified	0.001	0.999	0.000
J01.4 Acute pansinusitis	0.001	0.999	0.000
J01.3 Acute sphenoidal sinusitis	0.001	0.999	0.000
K51.8 Other ulcerative colitis	0.001	0.999	0.000
K65.0 Acute peritonitis	0.001	0.999	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.999	0.001
C39.9 Ill-defined sites within the respiratory system	0.000	0.999	0.001
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.999	0.001
C39.0 Upper respiratory tract, part unspecified	0.000	0.999	0.001
C91.9 Lymphoid leukaemia, unspecified	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.000	0.999	0.001
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.999	0.001
K51 Ulcerative colitis	0.001	0.999	0.000
I84.3 External thrombosed haemorrhoids	0.001	0.999	0.000
J01.8 Other acute sinusitis	0.001	0.999	0.000
Q61.3 Polycystic kidney, unspecified	0.001	0.999	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.999	0.001
G63.2 Diabetic polyneuropathy	0.000	0.999	0.001
J39.8 Other specified diseases of upper respiratory tract	0.000	0.999	0.001
M24.5 Contracture of joint	0.000	0.999	0.001
R23.0 Cyanosis	0.000	0.999	0.001
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.001	0.999	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.999	0.001
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.999	0.001
H93.8 Other specified disorders of ear	0.000	0.999	0.001
S70.8 Other superficial injuries of hip and thigh	0.001	0.999	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.001	0.999	0.000
T36.0 Penicillins	0.000	0.999	0.001
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.999	0.000
C32 Malignant neoplasm of larynx	0.000	0.999	0.001
M24.57 Contracture of joint (Ankle and foot)	0.000	0.999	0.001
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.001	0.999	0.000
S70 Superficial injury of hip and thigh	0.001	0.999	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.001	0.999	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.999	0.001
K51.9 Ulcerative colitis, unspecified	0.001	0.999	0.000
B07 Viral warts	0.001	0.999	0.000
C30.1 Middle ear	0.000	0.999	0.001
D76.3 Other histiocytosis syndromes	0.000	0.999	0.001
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.999	0.001
Q61.5 Medullary cystic kidney	0.001	0.999	0.000
M24.59 Contracture of joint (Site unspecified)	0.000	0.999	0.001
M24.58 Contracture of joint (Other)	0.000	0.999	0.001
M24.53 Contracture of joint (Forearm)	0.000	0.999	0.001
M24.50 Contracture of joint (Multiple sites)	0.000	0.999	0.001
M48.07 Spinal stenosis (Lumbosacral region)	0.001	0.999	0.000
C32.2 Subglottis	0.000	0.999	0.001
C71.0 Cerebrum, except lobes and ventricles	0.001	0.999	0.000
G90.3 Multisystem degeneration	0.000	0.999	0.001
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.999	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.999	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M24.52 Contracture of joint (Upper arm)	0.000	0.999	0.001
M24.51 Contracture of joint (Shoulder region)	0.000	0.999	0.001
M70.22 Olecranon bursitis-Upper arm	0.001	0.999	0.000
C32.8 Overlapping lesion of larynx	0.000	0.999	0.001
G03.0 Nonpyogenic meningitis	0.001	0.999	0.000
G30.8 Other Alzheimer's disease	0.001	0.999	0.000
S70.0 Contusion of hip	0.001	0.999	0.000
T09.3 Injury of spinal cord, level unspecified	0.001	0.999	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
T09 Other injuries of spine and trunk, level unspecified	0.001	0.999	0.000
M67.43 Ganglion, wrist	0.000	0.999	0.001
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.999	0.001
E13.9 Without complications	0.000	0.999	0.001
I95.2 Hypotension due to drugs	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.001	0.999	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.999	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.999	0.001
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.999	0.001
K51.3 Ulcerative (chronic) rectosigmoiditis	0.001	0.999	0.000
L53.0 Toxic erythema	0.000	0.999	0.001
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
Z99.2 Dependence on renal dialysis	0.001	0.999	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
C32.3 Laryngeal cartilage	0.000	0.999	0.001
E21.0 Primary hyperparathyroidism	0.000	0.999	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.999	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations