TreeWAS – Variant ID: rs4646284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C61 Malignant neoplasm of prostate	1.000	0.000	0.000
C60-C63 Malignant neoplasms of male genital organs	0.463	0.537	0.000
C60 Malignant neoplasm of penis	0.363	0.637	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.349	0.651	0.000
C60.0 Prepuce	0.310	0.690	0.000
C62 Malignant neoplasm of testis	0.300	0.700	0.000
C63.2 Scrotum	0.267	0.732	0.000
C60.8 Overlapping lesion of penis	0.260	0.740	0.000
C60.2 Body of penis	0.260	0.740	0.000
C60.1 Glans penis	0.258	0.742	0.000
C63.9 Male genital organ, unspecified	0.250	0.749	0.000
C63.8 Overlapping lesion of male genital organs	0.250	0.749	0.000
C63.7 Other specified male genital organs	0.250	0.749	0.000
C63.1 Spermatic cord	0.250	0.749	0.000
C63.0 Epididymis	0.250	0.749	0.000
C62.1 Descended testis	0.247	0.753	0.000
C60.9 Penis, unspecified	0.226	0.774	0.000
C62.0 Undescended testis	0.215	0.785	0.000
Z85.4 Personal history of malignant neoplasm of genital organs	0.139	0.861	0.000
C62.9 Testis, unspecified	0.114	0.886	0.000
G47.3 Sleep apnoea	0.000	0.903	0.097
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.935	0.065
T39.0 Salicylates	0.000	0.935	0.065
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.936	0.064
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.938	0.062
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.939	0.061
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.940	0.060
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.946	0.054
T42.4 Benzodiazepines	0.000	0.947	0.053
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.947	0.052
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.949	0.051
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.951	0.049
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.952	0.048
T39.4 Antirheumatics, not elsewhere classified	0.000	0.953	0.047
T39.2 Pyrazolone derivatives	0.000	0.953	0.047
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.953	0.047
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.953	0.047
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.953	0.047
T42.0 Hydantoin derivatives	0.000	0.953	0.046
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.955	0.045
T36 Poisoning by systemic antibiotics	0.000	0.955	0.045
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.956	0.044
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.956	0.044
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.956	0.044
T42.3 Barbiturates	0.000	0.956	0.044
T42.2 Succinimides and oxazolidinediones	0.000	0.956	0.044
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.957	0.043
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.957	0.043
T42.1 Iminostilbenes	0.000	0.957	0.043
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.957	0.043
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.958	0.042
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.959	0.041
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.959	0.041
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.961	0.039
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.961	0.039
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.961	0.039
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.961	0.039
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.961	0.039
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.961	0.039
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.961	0.039
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.961	0.039
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.961	0.039
T44.0 Anticholinesterase agents	0.000	0.961	0.039
T43.2 Other and unspecified antidepressants	0.000	0.962	0.038
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.963	0.037
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.963	0.037
T46.7 Peripheral vasodilators	0.000	0.963	0.037
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.963	0.037
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.963	0.037
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.963	0.037
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.963	0.036
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.964	0.036
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.964	0.036
T43.6 Psychostimulants with abuse potential	0.000	0.964	0.036
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.964	0.036
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.964	0.036
T37.5 Antiviral drugs	0.000	0.964	0.036
T37.4 Anthelminthics	0.000	0.964	0.036
T37.3 Other antiprotozoal drugs	0.000	0.964	0.036
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.964	0.036
T37.1 Antimycobacterial drugs	0.000	0.964	0.036
T37.0 Sulphonamides	0.000	0.964	0.036
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.965	0.035
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.966	0.034
T43.9 Psychotropic drug, unspecified	0.000	0.966	0.034
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.966	0.034
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.966	0.034
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.966	0.034
T47.7 Emetics	0.000	0.966	0.034
T47.6 Antidiarrhoeal drugs	0.000	0.966	0.034
T47.5 Digestants	0.000	0.966	0.034
T47.3 Saline and osmotic laxatives	0.000	0.966	0.034
T47.2 Stimulant laxatives	0.000	0.966	0.034
T47.0 Histamine H(2)-receptor antagonists	0.000	0.966	0.034
T40.4 Other synthetic narcotics	0.000	0.967	0.033
T36.0 Penicillins	0.000	0.967	0.033
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.967	0.033
T36.9 Systemic antibiotic, unspecified	0.000	0.968	0.032
T36.8 Other systemic antibiotics	0.000	0.968	0.032
T36.7 Antifungal antibiotics, systemically used	0.000	0.968	0.032
T36.6 Rifamycins	0.000	0.968	0.032
T36.5 Aminoglycosides	0.000	0.968	0.032
T36.4 Tetracyclines	0.000	0.968	0.032
T36.3 Macrolides	0.000	0.968	0.032
T36.2 Chloramphenicol group	0.000	0.968	0.032
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.968	0.032
T41.5 Therapeutic gases	0.000	0.968	0.032
T41.4 Anaesthetic, unspecified	0.000	0.968	0.032
T41.3 Local anaesthetics	0.000	0.968	0.032
T41.2 Other and unspecified general anaesthetics	0.000	0.968	0.032
T41.1 Intravenous anaesthetics	0.000	0.968	0.032
T41.0 Inhaled anaesthetics	0.000	0.968	0.032
T49.9 Topical agent, unspecified	0.000	0.968	0.032
T49.8 Other topical agents	0.000	0.968	0.032
T49.7 Dental drugs, topically applied	0.000	0.968	0.032
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.968	0.032
T49.5 Ophthalmological drugs and preparations	0.000	0.968	0.032
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.968	0.032
T49.3 Emollients, demulcents and protectants	0.000	0.968	0.032
T49.2 Local astringents and local detergents	0.000	0.968	0.032
T49.1 Antipruritics	0.000	0.968	0.032
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.968	0.032
T40.5 Cocaine	0.000	0.969	0.031
T50.4 Drugs affecting uric acid metabolism	0.000	0.969	0.031
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.969	0.031
T40.8 Lysergide [LSD]	0.000	0.969	0.031
T40.7 Cannabis (derivatives)	0.000	0.969	0.031
T40.3 Methadone	0.000	0.969	0.031
T40.1 Heroin	0.000	0.969	0.031
T40.0 Opium	0.000	0.969	0.031
T40.2 Other opioids	0.000	0.969	0.031
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.970	0.030
T48.5 Anti-common-cold drugs	0.000	0.970	0.030
T48.4 Expectorants	0.000	0.970	0.030
T48.3 Antitussives	0.000	0.970	0.030
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.970	0.030
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.970	0.030
T48.0 Oxytocic drugs	0.000	0.970	0.030
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.970	0.030
T47.4 Other laxatives	0.000	0.970	0.029
T50.7 Analeptics and opioid receptor antagonists	0.000	0.971	0.029
T50.5 Appetite depressants	0.000	0.971	0.029
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.971	0.029
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.971	0.029
T50.1 Loop [high-ceiling] diuretics	0.000	0.971	0.029
T50.0 Mineralocorticoids and their antagonists	0.000	0.971	0.029
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.971	0.029
T50.8 Diagnostic agents	0.000	0.971	0.029
T46.1 Calcium-channel blockers	0.000	0.972	0.028
T45.2 Vitamins, not elsewhere classified	0.000	0.972	0.028
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.972	0.028
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.972	0.027
T40.6 Other and unspecified narcotics	0.000	0.973	0.027
T38.1 Thyroid hormones and substitutes	0.000	0.973	0.027
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.973	0.027
T45.8 Other primarily systemic and haematological agents	0.000	0.973	0.027
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.973	0.027
T45.6 Fibrinolysis-affecting drugs	0.000	0.973	0.027
T45.4 Iron and its compounds	0.000	0.973	0.027
T45.3 Enzymes, not elsewhere classified	0.000	0.973	0.027
T45.0 Antiallergic and antiemetic drugs	0.000	0.974	0.026
T38.9 Other and unspecified hormone antagonists	0.000	0.974	0.025
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.974	0.025
T38.7 Androgens and anabolic congeners	0.000	0.974	0.025
T38.5 Other oestrogens and progestogens	0.000	0.974	0.025
T38.4 Oral contraceptives	0.000	0.974	0.025
T38.2 Antithyroid drugs	0.000	0.974	0.025
T38.0 Glucocorticoids and synthetic analogues	0.000	0.974	0.025
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.975	0.025
T45.5 Anticoagulants	0.000	0.976	0.023
T39.1 4-Aminophenol derivatives	0.000	0.977	0.023
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.978	0.022
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.979	0.021
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.979	0.020
F17.2 Dependence syndrome	0.013	0.987	0.000
M75.1 Rotator cuff syndrome	0.011	0.989	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.010	0.990	0.000
M35.3 Polymyalgia rheumatica	0.000	0.991	0.009
C25.9 Pancreas, unspecified	0.000	0.992	0.008
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.008	0.992	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.992	0.008
Z50.5 Speech therapy	0.000	0.993	0.007
C25 Malignant neoplasm of pancreas	0.000	0.993	0.007
C25.1 Body of pancreas	0.000	0.993	0.007
M54.36 Sciatica (Lumbar region)	0.007	0.993	0.000
C25.3 Pancreatic duct	0.000	0.993	0.006
D86.0 Sarcoidosis of lung	0.000	0.994	0.006
C25.0 Head of pancreas	0.000	0.994	0.006
G47 Sleep disorders	0.000	0.994	0.006
S92.00 Fracture of calcaneus (closed)	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.994	0.006
C25.7 Other parts of pancreas	0.000	0.995	0.005
C25.4 Endocrine pancreas	0.000	0.995	0.005
C25.2 Tail of pancreas	0.000	0.995	0.005
W55.0 Home	0.005	0.995	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.995	0.005
J98.4 Other disorders of lung	0.000	0.995	0.005
G47.2 Disorders of the sleep-wake schedule	0.000	0.995	0.005
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
D86 Sarcoidosis	0.000	0.996	0.004
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.996	0.004
J98.8 Other specified respiratory disorders	0.000	0.996	0.004
J98 Other respiratory disorders	0.000	0.996	0.004
D04.5 Skin of trunk	0.004	0.996	0.000
G47.8 Other sleep disorders	0.000	0.996	0.004
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.004
S82.40 Fracture of fibula alone (closed)	0.004	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.996	0.004
S82.20 Fracture of shaft of tibia (closed)	0.000	0.996	0.004
D13.2 Duodenum	0.000	0.996	0.004
J98.9 Respiratory disorder, unspecified	0.000	0.996	0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
J98.2 Interstitial emphysema	0.000	0.996	0.004
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.996	0.004
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.004	0.996	0.000
S92.0 Fracture of calcaneus	0.004	0.996	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.997	0.003
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M23.8 Other internal derangements of knee	0.000	0.997	0.003
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
D38.1 Trachea, bronchus and lung	0.000	0.997	0.003
J98.3 Compensatory emphysema	0.000	0.997	0.003
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
K06 Other disorders of gingiva and edentulous alveolar ridge	0.003	0.997	0.000
J98.6 Disorders of diaphragm	0.000	0.997	0.003
M07.3 Other psoriatic arthropathies	0.003	0.997	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.997	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.997	0.003
G47.4 Narcolepsy and cataplexy	0.000	0.997	0.003
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
N21.0 Calculus in bladder	0.003	0.997	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.997	0.003
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
M07.38 Other psoriatic arthropathies (Other)	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.997	0.003
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.997	0.003
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.003	0.997	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.997	0.003
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
I49.1 Atrial premature depolarisation	0.003	0.997	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.997	0.003
M79.8 Other specified soft tissue disorders	0.000	0.997	0.003
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
F52.2 Failure of genital response	0.000	0.997	0.003
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
J34.0 Abscess, furuncle and carbuncle of nose	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
D86.8 Sarcoidosis of other and combined sites	0.000	0.997	0.002
G93.3 Postviral fatigue syndrome	0.000	0.997	0.003
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.003	0.997	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.002
K06.0 Gingival recession	0.002	0.997	0.000
G47.9 Sleep disorder, unspecified	0.000	0.997	0.003
S82.2 Fracture of shaft of tibia	0.000	0.997	0.003
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.997	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.997	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.997	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.002	0.997	0.001
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.997	0.003
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.997	0.000
W55 Bitten or struck by other mammals	0.002	0.997	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
W29.9 Unspecified place	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.998	0.002
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
H34.1 Central retinal artery occlusion	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
F17.9 Unspecified mental and behavioural disorder	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.000	0.998	0.002
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.000	0.998	0.002
Z91.5 Personal history of self-harm	0.000	0.998	0.002
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.998	0.002
F17.8 Other mental and behavioural disorders	0.002	0.998	0.000
F17.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
F17.6 Amnesic syndrome	0.002	0.998	0.000
F17.5 Psychotic disorder	0.002	0.998	0.000
F17.4 Withdrawal state with delirium	0.002	0.998	0.000
F17.3 Withdrawal state	0.002	0.998	0.000
F17.0 Acute intoxication	0.002	0.998	0.000
K06.1 Gingival enlargement	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
H34 Retinal vascular occlusions	0.000	0.998	0.002
M47.80 Other spondylosis (Multiple sites in spine)	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
W55.9 Unspecified place	0.002	0.998	0.000
W55.5 Trade and service area	0.002	0.998	0.000
W55.6 Industrial and construction area	0.002	0.998	0.000
W55.4 Street and highway	0.002	0.998	0.000
W55.3 Sports and athletics area	0.002	0.998	0.000
W55.2 School, other institution and public administrative area	0.002	0.998	0.000
W55.1 Residential institution	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.000	0.998	0.002
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.998	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
E10.4 With neurological complications	0.000	0.998	0.002
E10.1 With ketoacidosis	0.000	0.998	0.002
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
H31 Other disorders of choroid	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M35 Other systemic involvement of connective tissue	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
L03.3 Cellulitis of trunk	0.000	0.998	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.002	0.998	0.000
H31.3 Choroidal haemorrhage and rupture	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.998	0.002
W55.7 Farm	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.998	0.002
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q05 Spina bifida	0.002	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.000	0.998	0.002
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.000	0.998	0.002
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.000	0.998	0.002
Q83.8 Other congenital malformations of breast	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.001	0.998	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.001	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.998	0.002
M54.3 Sciatica	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
H11.0 Pterygium	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
H31.1 Choroidal degeneration	0.000	0.998	0.002
M35.7 Hypermobility syndrome	0.000	0.998	0.002
M35.2 Behcet's disease	0.000	0.998	0.002
M60.9 Myositis, unspecified	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
H31.9 Disorder of choroid, unspecified	0.000	0.998	0.002
H31.4 Choroidal detachment	0.000	0.998	0.002
H31.2 Hereditary choroidal dystrophy	0.000	0.998	0.002
N21.8 Other lower urinary tract calculus	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.998	0.002
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.998	0.002
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.998	0.002
M35.5 Multifocal fibrosclerosis	0.000	0.998	0.002
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
D38.0 Larynx	0.000	0.998	0.002
M35.1 Other overlap syndromes	0.000	0.998	0.002
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
W55.8 Other specified place	0.001	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
H34.2 Other retinal artery occlusions	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.998	0.000
Z84.1 Family history of disorders of the kidney and ureter	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
N21 Calculus of lower urinary tract	0.002	0.998	0.000
R80 Isolated proteinuria	0.000	0.998	0.002
C84.5 Other and unspecified T-cell lymphomas	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.998	0.001
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.001	0.998	0.000
Q83.3 Accessory nipple	0.001	0.998	0.000
Q83.2 Absent nipple	0.001	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
Q03 Congenital hydrocephalus	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.998	0.002
D38.6 Respiratory organ, unspecified	0.000	0.998	0.001
D38.5 Other respiratory organs	0.000	0.998	0.001
D38.4 Thymus	0.000	0.998	0.001
D38.3 Mediastinum	0.000	0.998	0.001
D38.2 Pleura	0.000	0.998	0.001
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M60.96 Myositis, unspecified (Lower leg)	0.001	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.002	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.001	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
W51.9 Unspecified place	0.002	0.998	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q04 Other congenital malformations of brain	0.001	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.998	0.002
S92.1 Fracture of talus	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.998	0.000
Q73 Reduction defects of unspecified limb	0.001	0.998	0.000
Q72 Reduction defects of lower limb	0.001	0.998	0.000
Q71 Reduction defects of upper limb	0.001	0.998	0.000
Q70 Syndactyly	0.001	0.998	0.000
Q69 Polydactyly	0.001	0.998	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.998	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.001	0.998	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.000	0.998	0.001
J15.1 Pneumonia due to Pseudomonas	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations