TreeWAS – Variant ID: rs4656345

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.5 Hyperlipidaemia, unspecified	0.000	0.705	0.295
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.926	0.074
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.939	0.060
E78.8 Other disorders of lipoprotein metabolism	0.000	0.946	0.053
E78.6 Lipoprotein deficiency	0.000	0.947	0.053
E78.3 Hyperchylomicronaemia	0.000	0.947	0.053
E78.1 Pure hyperglyceridaemia	0.000	0.947	0.053
E78.4 Other hyperlipidaemia	0.000	0.948	0.052
E78.2 Mixed hyperlipidaemia	0.000	0.954	0.046
H00.1 Chalazion	0.025	0.975	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.976	0.024
H00 Hordeolum and chalazion	0.019	0.981	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.018	0.981	0.000
N18.3 Chronic kidney disease, stage 3	0.009	0.991	0.000
E11.3 With ophthalmic complications	0.006	0.994	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.995	0.005
N18 Chronic renal failure	0.005	0.995	0.000
N17.9 Acute renal failure, unspecified	0.005	0.995	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.005	0.995	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.005	0.995	0.000
Y52 Agents primarily affecting the cardiovascular system	0.005	0.995	0.000
N17 Acute renal failure	0.005	0.995	0.000
N18.4 Chronic kidney disease, stage 4	0.005	0.995	0.000
N18.5 Chronic kidney disease, stage 5	0.005	0.995	0.000
Y40 Systemic antibiotics	0.005	0.995	0.000
M21.6 Other acquired deformities of ankle and foot	0.005	0.995	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
N17-N19 Renal failure	0.004	0.996	0.000
W44.0 Home	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.004	0.996	0.000
M21.2 Flexion deformity	0.004	0.996	0.000
W44 Foreign body entering into or through eye or natural orifice	0.004	0.996	0.000
W20-W49 Exposure to inanimate mechanical forces	0.004	0.996	0.000
M21 Other acquired deformities of limbs	0.004	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
E11.4 With neurological complications	0.004	0.996	0.000
Y57 Other and unspecified drugs and medicaments	0.004	0.996	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
N18.8 Other chronic renal failure	0.004	0.996	0.000
N18.1 Chronic kidney disease, stage 1	0.004	0.996	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
W22 Striking against or struck by other objects	0.004	0.996	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
M21.24 Flexion deformity (Hand)	0.004	0.996	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
N19 Unspecified renal failure	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
Chapter XX External causes of morbidity and mortality	0.004	0.996	0.000
N18.2 Chronic kidney disease, stage 2	0.004	0.996	0.000
M21.1 Varus deformity, not elsewhere classified	0.004	0.996	0.000
W22.9 Unspecified place	0.004	0.996	0.000
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.004	0.996	0.000
Y48 Anaesthetics and therapeutic gases	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
Y95 Nosocomial condition	0.004	0.996	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.004	0.996	0.000
M21.27 Flexion deformity (Ankle and foot)	0.004	0.996	0.000
Y59 Other and unspecified vaccines and biological substances	0.004	0.996	0.000
Y58 Bacterial vaccines	0.004	0.996	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.996	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.004	0.996	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.004	0.996	0.000
N17.8 Other acute renal failure	0.004	0.996	0.000
N17.2 Acute renal failure with medullary necrosis	0.004	0.996	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.004	0.996	0.000
N17.0 Acute renal failure with tubular necrosis	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.996	0.000
Y40.7 Antifungal antibiotics, systemically used	0.003	0.996	0.000
Y40.6 Rifamycins	0.003	0.996	0.000
Y40.5 Aminoglycosides	0.003	0.996	0.000
Y40.4 Tetracyclines	0.003	0.996	0.000
Y40.2 Chloramphenicol group	0.003	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.996	0.000
Q63 Other congenital malformations of kidney	0.003	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
E11 Non-insulin-dependent diabetes mellitus	0.004	0.996	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.996	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.996	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.996	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.996	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.996	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.996	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.996	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.996	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.996	0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.003	0.996	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.996	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.003	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
Y54.0 Mineralocorticoids	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
W29 Contact with other powered hand tools and household machinery	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y83.6 Removal of other organ (partial) (total)	0.003	0.997	0.000
K08.3 Retained dental root	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.003	0.997	0.000
M21.29 Flexion deformity (Site unspecified)	0.003	0.997	0.000
M21.28 Flexion deformity (Other)	0.003	0.997	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.003	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.003	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.003	0.997	0.000
W44.9 Unspecified place	0.003	0.997	0.000
W44.5 Trade and service area	0.003	0.997	0.000
W44.8 Other specified place	0.003	0.997	0.000
W44.7 Farm	0.003	0.997	0.000
W44.6 Industrial and construction area	0.003	0.997	0.000
W44.4 Street and highway	0.003	0.997	0.000
W44.3 Sports and athletics area	0.003	0.997	0.000
W44.2 School, other institution and public administrative area	0.003	0.997	0.000
W44.1 Residential institution	0.003	0.997	0.000
M21.9 Acquired deformity of limb, unspecified	0.003	0.997	0.000
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
M21.7 Unequal limb length (acquired)	0.003	0.997	0.000
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997	0.000
O04.9 Complete or unspecified, without complication	0.003	0.997	0.000
W46 Contact with hypodermic needle	0.003	0.997	0.000
W45 Foreign body or object entering through skin	0.003	0.997	0.000
W43 Exposure to vibration	0.003	0.997	0.000
W42 Exposure to noise	0.003	0.997	0.000
W41 Exposure to high-pressure jet	0.003	0.997	0.000
W40 Explosion of other materials	0.003	0.997	0.000
W39 Discharge of firework	0.003	0.997	0.000
W38 Explosion and rupture of other specified pressurised devices	0.003	0.997	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.003	0.997	0.000
W36 Explosion and rupture of gas cylinder	0.003	0.997	0.000
W35 Explosion and rupture of boiler	0.003	0.997	0.000
W34 Discharge from other and unspecified firearms	0.003	0.997	0.000
W33 Rifle, shotgun and larger firearm discharge	0.003	0.997	0.000
W32 Handgun discharge	0.003	0.997	0.000
W31 Contact with other and unspecified machinery	0.003	0.997	0.000
W30 Contact with agricultural machinery	0.003	0.997	0.000
W28 Contact with powered lawn mower	0.003	0.997	0.000
W27 Contact with nonpowered hand tool	0.003	0.997	0.000
W26 Contact with knife, sword or dagger	0.003	0.997	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.003	0.997	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.003	0.997	0.000
W21 Striking against or struck by sports equipment	0.003	0.997	0.000
W20 Struck by thrown, projected or falling object	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
V80-V89 Other land transport accidents	0.003	0.997	0.000
E11.2 With renal complications	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Y00-Y09 Assault	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
X20-X29 Contact with venomous animals and plants	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
W25 Contact with sharp glass	0.003	0.997	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.997	0.000
W50-W64 Exposure to animate mechanical forces	0.003	0.997	0.000
V40-V49 Car occupant injured in transport accident	0.003	0.997	0.000
Q05 Spina bifida	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
X50-X57 Overexertion, travel and privation	0.003	0.997	0.000
N18.0 End-stage renal disease	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
W22.8 Other specified place	0.003	0.997	0.000
W22.6 Industrial and construction area	0.003	0.997	0.000
W22.4 Street and highway	0.003	0.997	0.000
W22.0 Home	0.003	0.997	0.000
W22.7 Farm	0.003	0.997	0.000
W22.5 Trade and service area	0.003	0.997	0.000
W22.3 Sports and athletics area	0.003	0.997	0.000
W22.2 School, other institution and public administrative area	0.003	0.997	0.000
W22.1 Residential institution	0.003	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
M23.3 Other meniscus derangements	0.003	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y53.7 Emetics	0.003	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.003	0.997	0.000
Y53.5 Digestants	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.003	0.997	0.000
Y53.2 Stimulant laxatives	0.003	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.997	0.000
Y35-Y36 Legal intervention and operations of war	0.003	0.997	0.000
Y10-Y34 Event of undetermined intent	0.003	0.997	0.000
X85-X99 Assault	0.003	0.997	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.003	0.997	0.000
X30-X39 Exposure to forces of nature	0.003	0.997	0.000
X10-X19 Contact with heat and hot substances	0.003	0.997	0.000
X00-X09 Exposure to smoke, fire and flames	0.003	0.997	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.003	0.997	0.000
W75-W84 Other accidental threats to breathing	0.003	0.997	0.000
W65-W74 Accidental drowning and submersion	0.003	0.997	0.000
V98-V99 Other and unspecified transport accidents	0.003	0.997	0.000
V95-V97 Air and space transport accidents	0.003	0.997	0.000
V90-V94 Water transport accidents	0.003	0.997	0.000
V70-V79 Bus occupant injured in transport accident	0.003	0.997	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.003	0.997	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.003	0.997	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.003	0.997	0.000
V01-V09 Pedestrian injured in transport accident	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
Y48.3 Local anaesthetics	0.003	0.997	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.003	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
Y48.1 Parenteral anaesthetics	0.003	0.997	0.000
Y48.0 Inhaled anaesthetics	0.003	0.997	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.003	0.997	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.003	0.997	0.000
Y98 Lifestyle-related condition	0.003	0.997	0.000
Y97 Environmental-pollution-related condition	0.003	0.997	0.000
Y96 Work-related condition	0.003	0.997	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.997	0.000
Y47.4 Bromine compounds	0.003	0.997	0.000
Y47.3 Paraldehyde	0.003	0.997	0.000
Y47.2 Chloral derivatives	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.003	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.003	0.997	0.000
Y50.8 Other central nervous system stimulants	0.003	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.003	0.997	0.000
Y50.1 Opioid receptor antagonists	0.003	0.997	0.000
Y50.0 Analeptics	0.003	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
Y55.5 Anticommon cold drugs	0.003	0.997	0.000
Y55.4 Expectorants	0.003	0.997	0.000
Y55.3 Antitussives	0.003	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
Y55.0 Oxytocic drugs	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.003	0.997	0.000
Y56.8 Other topical agents	0.003	0.997	0.000
Y56.7 Dental drugs, topically applied	0.003	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56.2 Local astringents and local detergents	0.003	0.997	0.000
Y56.1 Antipruritics	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.003	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.003	0.997	0.000
Y59.3 Immunoglobulin	0.003	0.997	0.000
Y59.2 Protozoal vaccines	0.003	0.997	0.000
Y59.1 Rickettsial vaccines	0.003	0.997	0.000
Y59.0 Viral vaccines	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
Y83.5 Amputation of limb(s)	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
Q21.1 Atrial septal defect	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
E11.1 With ketoacidosis	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.997	0.000
Q83.1 Accessory breast	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
X60-X84 Intentional self-harm	0.003	0.997	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.997	0.000
E11.8 With unspecified complications	0.003	0.997	0.000
E11.7 With multiple complications	0.003	0.997	0.000
E11.0 With coma	0.003	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
B95-B98 Bacterial, viral and other infectious agents	0.003	0.997	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
Y83.3 Surgical operation with formation of external stoma	0.003	0.997	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
X23 Contact with hornets, wasps and bees	0.003	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.003	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.003	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.003	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.003	0.997	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.003	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.003	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.003	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.003	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.003	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.997	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.003	0.997	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
W29.9 Unspecified place	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Y00 Assault by blunt object	0.003	0.997	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.997	0.000
V20-V29 Motorcycle rider injured in transport accident	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
W49.9 Unspecified place	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
Y41.5 Antiviral drugs	0.002	0.997	0.000
Y41.4 Anthelminthics	0.002	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
Y41.1 Antimycobacterial drugs	0.002	0.997	0.000
Y41.0 Sulphonamides	0.002	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.003	0.997	0.000
W29.8 Other specified place	0.002	0.997	0.000
W29.6 Industrial and construction area	0.002	0.997	0.000
W29.0 Home	0.002	0.997	0.000
W29.7 Farm	0.002	0.997	0.000
W29.5 Trade and service area	0.002	0.997	0.000
W29.4 Street and highway	0.002	0.997	0.000
W29.3 Sports and athletics area	0.002	0.997	0.000
W29.2 School, other institution and public administrative area	0.002	0.997	0.000
W29.1 Residential institution	0.002	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
V10-V19 Pedal cyclist injured in transport accident	0.003	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.997	0.000
Q61.8 Other cystic kidney diseases	0.002	0.997	0.000
Q61.5 Medullary cystic kidney	0.002	0.997	0.000
Q61.4 Renal dysplasia	0.002	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.997	0.000
W49.8 Other specified place	0.002	0.997	0.000
W49.7 Farm	0.002	0.997	0.000
W49.6 Industrial and construction area	0.002	0.997	0.000
W49.5 Trade and service area	0.002	0.997	0.000
W49.4 Street and highway	0.002	0.997	0.000
W49.3 Sports and athletics area	0.002	0.997	0.000
W49.2 School, other institution and public administrative area	0.002	0.997	0.000
W49.1 Residential institution	0.002	0.997	0.000
W49.0 Home	0.002	0.997	0.000
K08 Other disorders of teeth and supporting structures	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations