TreeWAS – Variant ID: rs4668356

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.9 Non-toxic goitre, unspecified	0.356	0.644	0.000
E04 Other non-toxic goitre	0.355	0.645	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.347	0.653	0.000
E00-E07 Disorders of thyroid gland	0.347	0.653	0.000
E05.9 Thyrotoxicosis, unspecified	0.343	0.657	0.000
E04.1 Non-toxic single thyroid nodule	0.318	0.682	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.311	0.689	0.000
E03 Other hypothyroidism	0.281	0.719	0.000
E04.2 Non-toxic multinodular goitre	0.272	0.728	0.000
E06 Thyroiditis	0.268	0.732	0.000
E05.8 Other thyrotoxicosis	0.268	0.732	0.000
E04.8 Other specified non-toxic goitre	0.254	0.745	0.000
E05.5 Thyroid crisis or storm	0.249	0.751	0.000
E05.4 Thyrotoxicosis factitia	0.249	0.751	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.249	0.751	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.249	0.751	0.000
E00 Congenital iodine-deficiency syndrome	0.249	0.751	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.248	0.752	0.000
E03.9 Hypothyroidism, unspecified	0.247	0.753	0.000
E04.0 Non-toxic diffuse goitre	0.247	0.753	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.240	0.760	0.000
E07 Other disorders of thyroid	0.234	0.766	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.224	0.776	0.000
E03.1 Congenital hypothyroidism without goitre	0.216	0.784	0.000
E06.3 Autoimmune thyroiditis	0.211	0.789	0.000
E06.1 Subacute thyroiditis	0.203	0.797	0.000
E03.5 Myxoedema coma	0.202	0.798	0.000
E03.4 Atrophy of thyroid (acquired)	0.202	0.798	0.000
E03.3 Postinfectious hypothyroidism	0.202	0.798	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.197	0.803	0.000
E06.4 Drug-induced thyroiditis	0.193	0.807	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.193	0.807	0.000
E06.0 Acute thyroiditis	0.193	0.807	0.000
E06.5 Other chronic thyroiditis	0.190	0.810	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.189	0.811	0.000
E06.9 Thyroiditis, unspecified	0.185	0.815	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.178	0.821	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.178	0.821	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.178	0.821	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.178	0.821	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.178	0.821	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.178	0.821	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.178	0.821	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.178	0.821	0.000
E07.8 Other specified disorders of thyroid	0.177	0.823	0.000
E03.8 Other specified hypothyroidism	0.171	0.829	0.000
E07.1 Dyshormogenetic goitre	0.168	0.832	0.000
E07.0 Hypersecretion of calcitonin	0.168	0.832	0.000
E07.9 Disorder of thyroid, unspecified	0.141	0.859	0.000
D25.9 Leiomyoma of uterus, unspecified	0.102	0.898	0.000
D25 Leiomyoma of uterus	0.061	0.939	0.000
D25.2 Subserosal leiomyoma of uterus	0.057	0.943	0.000
D25.0 Submucous leiomyoma of uterus	0.045	0.955	0.000
D25.1 Intramural leiomyoma of uterus	0.026	0.974	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.026	0.974	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.022	0.978	0.000
D51 Vitamin B12 deficiency anaemia	0.019	0.981	0.000
E20-E35 Disorders of other endocrine glands	0.019	0.981	0.000
D50.8 Other iron deficiency anaemias	0.018	0.982	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.017	0.983	0.000
E21.3 Hyperparathyroidism, unspecified	0.016	0.984	0.000
D50-D53 Nutritional anaemias	0.016	0.984	0.000
E28 Ovarian dysfunction	0.016	0.984	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.016	0.984	0.000
D50 Iron deficiency anaemia	0.016	0.984	0.000
E40-E46 Malnutrition	0.015	0.985	0.000
E32 Diseases of thymus	0.014	0.985	0.000
E50-E64 Other nutritional deficiencies	0.014	0.985	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.014	0.986	0.000
E27 Other disorders of adrenal gland	0.014	0.986	0.000
E20 Hypoparathyroidism	0.014	0.986	0.000
D51.2 Transcobalamin II deficiency	0.014	0.986	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.014	0.986	0.000
E29 Testicular dysfunction	0.014	0.986	0.000
E31 Polyglandular dysfunction	0.014	0.986	0.000
E25 Adrenogenital disorders	0.014	0.986	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.014	0.986	0.000
E30 Disorders of puberty, not elsewhere classified	0.014	0.986	0.000
E26 Hyperaldosteronism	0.014	0.986	0.000
E34 Other endocrine disorders	0.014	0.986	0.000
E28.2 Polycystic ovarian syndrome	0.013	0.987	0.000
E21.2 Other hyperparathyroidism	0.013	0.987	0.000
E23 Hypofunction and other disorders of pituitary gland	0.013	0.987	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.013	0.987	0.000
E21.4 Other specified disorders of parathyroid gland	0.013	0.987	0.000
E28.3 Primary ovarian failure	0.013	0.987	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.012	0.988	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.012	0.988	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.988	0.012
E27.4 Other and unspecified adrenocortical insufficiency	0.012	0.988	0.000
E22 Hyperfunction of pituitary gland	0.012	0.988	0.000
E24 Cushing's syndrome	0.012	0.988	0.000
D53 Other nutritional anaemias	0.012	0.988	0.000
E28.9 Ovarian dysfunction, unspecified	0.012	0.988	0.000
E28.8 Other ovarian dysfunction	0.012	0.988	0.000
E28.1 Androgen excess	0.012	0.988	0.000
E28.0 Oestrogen excess	0.012	0.988	0.000
D50.1 Sideropenic dysphagia	0.012	0.988	0.000
E65-E68 Obesity and other hyperalimentation	0.012	0.988	0.000
G91 Hydrocephalus	0.000	0.988	0.012
E15 Nondiabetic hypoglycaemic coma	0.011	0.988	0.000
E16 Other disorders of pancreatic internal secretion	0.012	0.988	0.000
D73.0 Hyposplenism	0.012	0.988	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.011	0.988	0.000
E23.7 Disorder of pituitary gland, unspecified	0.011	0.989	0.000
E58 Dietary calcium deficiency	0.011	0.989	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.011	0.989	0.000
E32.9 Disease of thymus, unspecified	0.011	0.989	0.000
E32.8 Other diseases of thymus	0.011	0.989	0.000
G91.1 Obstructive hydrocephalus	0.000	0.989	0.011
E44 Protein-energy malnutrition of moderate and mild degree	0.011	0.989	0.000
E45 Retarded development following protein-energy malnutrition	0.011	0.989	0.000
E43 Unspecified severe protein-energy malnutrition	0.011	0.989	0.000
E42 Marasmic kwashiorkor	0.011	0.989	0.000
E41 Nutritional marasmus	0.011	0.989	0.000
E40 Kwashiorkor	0.011	0.989	0.000
E56 Other vitamin deficiencies	0.011	0.989	0.000
E26.9 Hyperaldosteronism, unspecified	0.011	0.989	0.000
E20.9 Hypoparathyroidism, unspecified	0.011	0.989	0.000
E29.9 Testicular dysfunction, unspecified	0.011	0.989	0.000
D73 Diseases of spleen	0.011	0.989	0.000
E54 Ascorbic acid deficiency	0.011	0.989	0.000
E32.1 Abscess of thymus	0.010	0.989	0.000
E32.0 Persistent hyperplasia of thymus	0.010	0.989	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.011	0.989	0.000
E50 Vitamin A deficiency	0.011	0.989	0.000
E60 Dietary zinc deficiency	0.011	0.989	0.000
E59 Dietary selenium deficiency	0.011	0.989	0.000
E52 Niacin deficiency [pellagra]	0.011	0.989	0.000
E63 Other nutritional deficiencies	0.010	0.989	0.000
E27.5 Adrenomedullary hyperfunction	0.010	0.989	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.010	0.989	0.000
E27.0 Other adrenocortical overactivity	0.010	0.989	0.000
E27.9 Disorder of adrenal gland, unspecified	0.010	0.989	0.000
E31.0 Autoimmune polyglandular failure	0.010	0.990	0.000
E61 Deficiency of other nutrient elements	0.010	0.990	0.000
E20.0 Idiopathic hypoparathyroidism	0.010	0.990	0.000
E27.8 Other specified disorders of adrenal gland	0.010	0.990	0.000
E29.8 Other testicular dysfunction	0.010	0.990	0.000
E29.0 Testicular hyperfunction	0.010	0.990	0.000
E20.1 Pseudohypoparathyroidism	0.010	0.990	0.000
E20.8 Other hypoparathyroidism	0.010	0.990	0.000
E31.9 Polyglandular dysfunction, unspecified	0.010	0.990	0.000
E31.8 Other polyglandular dysfunction	0.010	0.990	0.000
E31.1 Polyglandular hyperfunction	0.010	0.990	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.010	0.990	0.000
E55 Vitamin D deficiency	0.010	0.990	0.000
E25.9 Adrenogenital disorder, unspecified	0.010	0.990	0.000
E25.8 Other adrenogenital disorders	0.010	0.990	0.000
E30.9 Disorder of puberty, unspecified	0.010	0.990	0.000
E30.8 Other disorders of puberty	0.010	0.990	0.000
E30.1 Precocious puberty	0.010	0.990	0.000
E30.0 Delayed puberty	0.010	0.990	0.000
E34.9 Endocrine disorder, unspecified	0.010	0.990	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.010	0.990	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.010	0.990	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.010	0.990	0.000
E27.2 Addisonian crisis	0.010	0.990	0.000
E26.8 Other hyperaldosteronism	0.010	0.990	0.000
E26.1 Secondary hyperaldosteronism	0.010	0.990	0.000
E51 Thiamine deficiency	0.010	0.990	0.000
E34.3 Short stature, not elsewhere classified	0.010	0.990	0.000
D73.5 Infarction of spleen	0.010	0.990	0.000
E23.2 Diabetes insipidus	0.010	0.990	0.000
E29.1 Testicular hypofunction	0.010	0.990	0.000
E34.5 Androgen resistance syndrome	0.010	0.990	0.000
E34.4 Constitutional tall stature	0.010	0.990	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.010	0.990	0.000
E34.1 Other hypersecretion of intestinal hormones	0.010	0.990	0.000
E34.0 Carcinoid syndrome	0.010	0.990	0.000
D52 Folate deficiency anaemia	0.010	0.990	0.000
E21.0 Primary hyperparathyroidism	0.010	0.990	0.000
E46 Unspecified protein-energy malnutrition	0.010	0.990	0.000
E23.1 Drug-induced hypopituitarism	0.009	0.990	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.009	0.990	0.000
E34.8 Other specified endocrine disorders	0.009	0.990	0.000
E53 Deficiency of other B group vitamins	0.009	0.990	0.000
E23.6 Other disorders of pituitary gland	0.009	0.991	0.000
E16.1 Other hypoglycaemia	0.009	0.991	0.000
E26.0 Primary hyperaldosteronism	0.009	0.991	0.000
E27.1 Primary adrenocortical insufficiency	0.009	0.991	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.991	0.009
E24.8 Other Cushing's syndrome	0.009	0.991	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
E24.2 Drug-induced Cushing's syndrome	0.009	0.991	0.000
G91.8 Other hydrocephalus	0.000	0.991	0.009
E22.1 Hyperprolactinaemia	0.009	0.991	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.991	0.009
D53.9 Nutritional anaemia, unspecified	0.009	0.991	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.009	0.991	0.000
D69 Purpura and other haemorrhagic conditions	0.009	0.991	0.000
D50.9 Iron deficiency anaemia, unspecified	0.009	0.991	0.000
E22.8 Other hyperfunction of pituitary gland	0.009	0.991	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.009	0.991	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.009	0.991	0.000
E24.3 Ectopic ACTH syndrome	0.009	0.991	0.000
E24.1 Nelson's syndrome	0.009	0.991	0.000
G91.0 Communicating hydrocephalus	0.000	0.991	0.009
D53.8 Other specified nutritional anaemias	0.009	0.991	0.000
D53.2 Scorbutic anaemia	0.009	0.991	0.000
D53.0 Protein deficiency anaemia	0.009	0.991	0.000
D73.8 Other diseases of spleen	0.009	0.991	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.009	0.991	0.000
E67 Other hyperalimentation	0.009	0.991	0.000
E68 Sequelae of hyperalimentation	0.009	0.991	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.008	0.991	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.991	0.008
E16.9 Disorder of pancreatic internal secretion, unspecified	0.008	0.991	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.008	0.991	0.000
E16.4 Abnormal secretion of gastrin	0.008	0.991	0.000
E16.3 Increased secretion of glucagon	0.008	0.991	0.000
E22.0 Acromegaly and pituitary gigantism	0.008	0.991	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.008	0.991	0.000
E65 Localised adiposity	0.008	0.992	0.000
A04 Other bacterial intestinal infections	0.008	0.992	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.008	0.992	0.000
E61.2 Magnesium deficiency	0.008	0.992	0.000
E56.1 Deficiency of vitamin K	0.008	0.992	0.000
E44.1 Mild protein-energy malnutrition	0.008	0.992	0.000
E44.0 Moderate protein-energy malnutrition	0.008	0.992	0.000
E56.9 Vitamin deficiency, unspecified	0.008	0.992	0.000
E56.8 Deficiency of other vitamins	0.008	0.992	0.000
E56.0 Deficiency of vitamin E	0.008	0.992	0.000
D73.2 Chronic congestive splenomegaly	0.008	0.992	0.000
D72 Other disorders of white blood cells	0.008	0.992	0.000
E50.9 Vitamin A deficiency, unspecified	0.008	0.992	0.000
E50.8 Other manifestations of vitamin A deficiency	0.008	0.992	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.008	0.992	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.008	0.992	0.000
E50.5 Vitamin A deficiency with night blindness	0.008	0.992	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.008	0.992	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.008	0.992	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.008	0.992	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.008	0.992	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.008	0.992	0.000
E63.8 Other specified nutritional deficiencies	0.008	0.992	0.000
E63.1 Imbalance of constituents of food intake	0.008	0.992	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.008	0.992	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.008	0.992	0.000
E64.8 Sequelae of other nutritional deficiencies	0.008	0.992	0.000
E64.3 Sequelae of rickets	0.008	0.992	0.000
E64.2 Sequelae of vitamin C deficiency	0.008	0.992	0.000
E64.1 Sequelae of vitamin A deficiency	0.008	0.992	0.000
E64.0 Sequelae of protein-energy malnutrition	0.008	0.992	0.000
D73.1 Hypersplenism	0.008	0.992	0.000
E63.9 Nutritional deficiency, unspecified	0.008	0.992	0.000
E24.9 Cushing's syndrome, unspecified	0.008	0.992	0.000
D73.9 Disease of spleen, unspecified	0.008	0.992	0.000
D68.9 Coagulation defect, unspecified	0.008	0.992	0.000
D68 Other coagulation defects	0.008	0.992	0.000
A04.5 Campylobacter enteritis	0.008	0.992	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.008	0.992	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.008	0.992	0.000
E61.9 Deficiency of nutrient element, unspecified	0.008	0.992	0.000
E61.8 Deficiency of other specified nutrient elements	0.008	0.992	0.000
E61.7 Deficiency of multiple nutrient elements	0.008	0.992	0.000
E61.6 Vanadium deficiency	0.008	0.992	0.000
E61.5 Molybdenum deficiency	0.008	0.992	0.000
E61.4 Chromium deficiency	0.008	0.992	0.000
E61.3 Manganese deficiency	0.008	0.992	0.000
E61.0 Copper deficiency	0.008	0.992	0.000
D73.3 Abscess of spleen	0.008	0.992	0.000
D69.0 Allergic purpura	0.008	0.992	0.000
E55.0 Rickets, active	0.007	0.992	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.992	0.008
G90 Disorders of autonomic nervous system	0.000	0.992	0.008
E16.2 Hypoglycaemia, unspecified	0.008	0.992	0.000
E51.9 Thiamine deficiency, unspecified	0.007	0.992	0.000
E51.8 Other manifestations of thiamine deficiency	0.007	0.992	0.000
E51.1 Beriberi	0.007	0.992	0.000
D69.5 Secondary thrombocytopenia	0.007	0.992	0.000
G90-G99 Other disorders of the nervous system	0.000	0.992	0.008
G93.0 Cerebral cysts	0.000	0.993	0.007
D52.8 Other folate deficiency anaemias	0.007	0.993	0.000
D52.1 Drug-induced folate deficiency anaemia	0.007	0.993	0.000
D52.0 Dietary folate deficiency anaemia	0.007	0.993	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.993	0.007
D73.4 Cyst of spleen	0.007	0.993	0.000
E55.9 Vitamin D deficiency, unspecified	0.007	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.007	0.993	0.000
D72.1 Eosinophilia	0.007	0.993	0.000
E53.1 Pyridoxine deficiency	0.007	0.993	0.000
E53.0 Riboflavin deficiency	0.007	0.993	0.000
C91 Lymphoid leukaemia	0.000	0.993	0.007
A04.9 Bacterial intestinal infection, unspecified	0.007	0.993	0.000
E51.2 Wernicke's encephalopathy	0.007	0.993	0.000
D69.2 Other nonthrombocytopenic purpura	0.007	0.993	0.000
G93 Other disorders of brain	0.000	0.993	0.007
D69.4 Other primary thrombocytopenia	0.007	0.993	0.000
E53.9 Vitamin B deficiency, unspecified	0.007	0.993	0.000
D69.8 Other specified haemorrhagic conditions	0.007	0.993	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.007	0.993	0.000
D68.8 Other specified coagulation defects	0.007	0.993	0.000
D74 Methaemoglobinaemia	0.007	0.993	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.007	0.993	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.007	0.993	0.000
D67 Hereditary factor IX deficiency	0.007	0.993	0.000
E61.1 Iron deficiency	0.006	0.993	0.000
D55-D59 Haemolytic anaemias	0.007	0.993	0.000
D69.1 Qualitative platelet defects	0.006	0.993	0.000
C91.4 Hairy-cell leukaemia	0.000	0.993	0.007
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.006	0.993	0.000
G90.3 Multisystem degeneration	0.000	0.993	0.006
E67.8 Other specified hyperalimentation	0.006	0.993	0.000
E67.3 Hypervitaminosis D	0.006	0.993	0.000
E67.2 Megavitamin-B6 syndrome	0.006	0.993	0.000
E67.1 Hypercarotenaemia	0.006	0.993	0.000
E67.0 Hypervitaminosis A	0.006	0.993	0.000
D72.8 Other specified disorders of white blood cells	0.006	0.994	0.000
D69.6 Thrombocytopenia, unspecified	0.006	0.994	0.000
C90.0 Multiple myeloma	0.000	0.994	0.006
G90.2 Horner's syndrome	0.000	0.994	0.006
A04.6 Enteritis due to Yersinia enterocolitica	0.006	0.994	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.006	0.994	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.006	0.994	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.006	0.994	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.006	0.994	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.006	0.994	0.000
D68.6 Other Thrombophilia	0.006	0.994	0.000
E53.8 Deficiency of other specified B group vitamins	0.006	0.994	0.000
G90.8 Other disorders of autonomic nervous system	0.000	0.994	0.006
D72.9 Disorder of white blood cells, unspecified	0.006	0.994	0.000
D72.0 Genetic anomalies of leukocytes	0.006	0.994	0.000
A04.4 Other intestinal Escherichia coli infections	0.006	0.994	0.000
D69.9 Haemorrhagic condition, unspecified	0.006	0.994	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.994	0.006
D68.1 Hereditary factor XI deficiency	0.006	0.994	0.000
D66 Hereditary factor VIII deficiency	0.006	0.994	0.000
C91.5 Adult T-cell leukaemia	0.000	0.994	0.006
G96 Other disorders of central nervous system	0.000	0.994	0.006
G90.4 Autonomic dysreflexia	0.000	0.994	0.006
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.994	0.006
G93.5 Compression of brain	0.000	0.994	0.006
D68.4 Acquired coagulation factor deficiency	0.006	0.994	0.000
D59 Acquired haemolytic anaemia	0.005	0.994	0.000
G92 Toxic encephalopathy	0.000	0.994	0.006
C91.9 Lymphoid leukaemia, unspecified	0.000	0.994	0.005
G93.3 Postviral fatigue syndrome	0.000	0.994	0.006
A04.8 Other specified bacterial intestinal infections	0.006	0.994	0.000
G93.4 Encephalopathy, unspecified	0.000	0.994	0.005
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.995	0.005
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.995	0.005
C91.0 Acute lymphoblastic leukaemia	0.000	0.995	0.005
K12 Stomatitis and related lesions	0.000	0.995	0.005
D52.9 Folate deficiency anaemia, unspecified	0.005	0.995	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.995	0.005
C91.7 Other lymphoid leukaemia	0.000	0.995	0.005
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.995	0.005
C91.3 Prolymphocytic leukaemia	0.000	0.995	0.005
C91.2 Subacute lymphocytic leukaemia	0.000	0.995	0.005
E23.0 Hypopituitarism	0.005	0.995	0.000
G93.9 Disorder of brain, unspecified	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.005	0.995	0.000
G93.2 Benign intracranial hypertension	0.000	0.995	0.005
G93.7 Reye's syndrome	0.000	0.995	0.005
E10-E14 Diabetes mellitus	0.005	0.995	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.995	0.005
N32.0 Bladder-neck obstruction	0.000	0.995	0.005
D76.3 Other histiocytosis syndromes	0.005	0.995	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.995	0.005
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
D57 Sickle-cell disorders	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.005	0.995	0.000
D74.8 Other methaemoglobinaemias	0.005	0.995	0.000
D74.0 Congenital methaemoglobinaemia	0.005	0.995	0.000
G95 Other diseases of spinal cord	0.000	0.995	0.005
D55 Anaemia due to enzyme disorders	0.005	0.995	0.000
D60-D64 Aplastic and other anaemias	0.005	0.995	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.995	0.005
D59.1 Other autoimmune haemolytic anaemias	0.005	0.995	0.000
D68.0 Von Willebrand's disease	0.005	0.995	0.000
E14.9 Without complications	0.005	0.995	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.005	0.995	0.000
E66 Obesity	0.005	0.995	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.995	0.005
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.995	0.005
D58 Other hereditary haemolytic anaemias	0.005	0.995	0.000
C90.1 Plasma cell leukaemia	0.000	0.995	0.005
K12.2 Cellulitis and abscess of mouth	0.000	0.995	0.005
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.995	0.004
D75 Other diseases of blood and blood-forming organs	0.004	0.995	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.004	0.995	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.996	0.004
L03.1 Cellulitis of other parts of limb	0.000	0.996	0.004
E14 Unspecified diabetes mellitus	0.004	0.996	0.000
K12.1 Other forms of stomatitis	0.000	0.996	0.004
D59.0 Drug-induced autoimmune haemolytic anaemia	0.004	0.996	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.996	0.004
K60.2 Anal fissure, unspecified	0.000	0.996	0.004
C90.3 Solitary plasmacytoma	0.000	0.996	0.004
D62 Acute posthaemorrhagic anaemia	0.004	0.996	0.000
D59.8 Other acquired haemolytic anaemias	0.004	0.996	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.004	0.996	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.004	0.996	0.000
D59.3 Haemolytic-uraemic syndrome	0.004	0.996	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.996	0.004
E66.2 Extreme obesity with alveolar hypoventilation	0.004	0.996	0.000
G96.8 Other specified disorders of central nervous system	0.000	0.996	0.004
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.996	0.004
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
C95 Leukaemia of unspecified cell type	0.000	0.996	0.004
K12.0 Recurrent oral aphthae	0.000	0.996	0.004
D57.1 Sickle-cell anaemia without crisis	0.004	0.996	0.000
G93.6 Cerebral oedema	0.000	0.996	0.004
G97.8 Other postprocedural disorders of nervous system	0.000	0.996	0.004
C86 Other specified types of T/NK-cell lymphoma	0.000	0.996	0.004
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
D56 Thalassaemia	0.004	0.996	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.996	0.004
D59.9 Acquired haemolytic anaemia, unspecified	0.004	0.996	0.000
E12 Malnutrition-related diabetes mellitus	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.000	0.996	0.004
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.996	0.004
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.996	0.004
D57.8 Other sickle-cell disorders	0.004	0.996	0.000
D57.2 Double heterozygous sickling disorders	0.004	0.996	0.000
D57.0 Sickle-cell anaemia with crisis	0.004	0.996	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.996	0.004
D55.9 Anaemia due to enzyme disorder, unspecified	0.004	0.996	0.000
D55.8 Other anaemias due to enzyme disorders	0.004	0.996	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.004	0.996	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.004	0.996	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.004	0.996	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.004	0.996	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.996	0.004
C88 Malignant immunoproliferative diseases	0.000	0.996	0.004
G93.8 Other specified disorders of brain	0.000	0.996	0.004
C83.1 Small cleaved cell (diffuse)	0.000	0.996	0.004
D68.5 Primary Thrombophilia	0.003	0.996	0.001
G95.2 Cord compression, unspecified	0.000	0.996	0.004
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.996	0.004
D75.2 Essential thrombocytosis	0.004	0.996	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.004	0.996	0.000
D57.3 Sickle-cell trait	0.003	0.996	0.000
C94 Other leukaemias of specified cell type	0.000	0.996	0.004
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.996	0.004
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.996	0.000
E66.0 Obesity due to excess calories	0.004	0.996	0.000
C81 Hodgkin's disease	0.000	0.996	0.004
E66.1 Drug-induced obesity	0.004	0.996	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.003	0.996	0.000
D58.1 Hereditary elliptocytosis	0.003	0.996	0.000
G94.1 Hydrocephalus in neoplastic disease	0.000	0.996	0.003
E13 Other specified diabetes mellitus	0.004	0.996	0.000
C93 Monocytic leukaemia	0.000	0.996	0.003
E14.4 With neurological complications	0.003	0.996	0.000
D58.0 Hereditary spherocytosis	0.003	0.996	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.004	0.996	0.000
C95.9 Leukaemia, unspecified	0.000	0.996	0.003
E14.0 With coma	0.003	0.996	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.996	0.003
D75.0 Familial erythrocytosis	0.003	0.997	0.000
E14.7 With multiple complications	0.003	0.997	0.000
D58.2 Other haemoglobinopathies	0.003	0.997	0.000
C95.0 Acute leukaemia of unspecified cell type	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.003
E14.2 Withrenal complications	0.003	0.997	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.997	0.003
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.997	0.003
C95.7 Other leukaemia of unspecified cell type	0.000	0.997	0.003
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.997	0.003
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.997	0.003
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.997	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
E14.6 With other specified complications	0.003	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.003
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.997	0.003
C86.4 Blastic NK-cell lymphoma	0.000	0.997	0.003
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.997	0.003
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.997	0.003
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.997	0.003
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.997	0.003
D56.8 Other thalassaemias	0.003	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.003	0.997	0.000
D56.2 Delta-beta thalassaemia	0.003	0.997	0.000
D56.0 Alpha thalassaemia	0.003	0.997	0.000
C83.7 Burkitt's tumour	0.000	0.997	0.003
E14.8 With unspecified complications	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.003	0.997	0.000
E12.9 Without complications	0.003	0.997	0.000
E12.8 With unspecified complications	0.003	0.997	0.000
E12.7 With multiple complications	0.003	0.997	0.000
E12.6 With other specified complications	0.003	0.997	0.000
E12.5 With peripheral circulatory complications	0.003	0.997	0.000
E12.4 With neurological complications	0.003	0.997	0.000
E12.3 With ophthalmic complications	0.003	0.997	0.000
E12.2 With renal complications	0.003	0.997	0.000
E12.1 With ketoacidosis	0.003	0.997	0.000
E12.0 With coma	0.003	0.997	0.000
E14.1 With ketoacidosis	0.003	0.997	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.997	0.003
C84.5 Other and unspecified T-cell lymphomas	0.000	0.997	0.003
C81.2 Mixed cellularity	0.000	0.997	0.003
C94.4 Acute panmyelosis	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations