TreeWAS – Variant ID: rs4669891

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter VII Diseases of the eye and adnexa	1.000	0.000
# Top node	1.000	0.000
H30-H36 Disorders of choroid and retina	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.996	0.004
Chapter IX Diseases of the circulatory system	0.995	0.005
I60-I69 Cerebrovascular diseases	0.995	0.005
N20-N23 Urolithiasis	0.994	0.006
Chapter I Certain infectious and parasitic diseases	0.994	0.006
N20 Calculus of kidney and ureter	0.992	0.008
H25-H28 Disorders of lens	0.992	0.008
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.989	0.011
N20.0 Calculus of kidney	0.986	0.014
Chapter II Neoplasms	0.985	0.015
H35 Other retinal disorders	0.984	0.016
B95-B98 Bacterial, viral and other infectious agents	0.983	0.017
H25 Senile cataract	0.980	0.020
I63 Cerebral infarction	0.979	0.021
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.978	0.022
Chapter VI Diseases of the nervous system	0.973	0.027
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.972	0.028
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.971	0.029
H25.1 Senile nuclear cataract	0.969	0.031
I64 Stroke, not specified as haemorrhage or infarction	0.966	0.034
Chapter IV Endocrine, nutritional and metabolic diseases	0.958	0.042
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.956	0.044
D00-D09 In situ neoplasms	0.954	0.046
N10-N16 Renal tubulo-interstitial diseases	0.951	0.049
Chapter XI Diseases of the digestive system	0.950	0.050
I63.9 Cerebral infarction, unspecified	0.945	0.055
H35.3 Degeneration of macula and posterior pole	0.938	0.062
I70-I79 Diseases of arteries, arterioles and capillaries	0.937	0.063
M20-M25 Other joint disorders	0.933	0.067
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.932	0.068
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.931	0.069
S00-S09 Injuries to the head	0.928	0.072
N13 Obstructive and reflux uropathy	0.926	0.074
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.923	0.077
H53-H54 Visual disturbances and blindness	0.918	0.082
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.916	0.084
E10-E14 Diabetes mellitus	0.916	0.084
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.913	0.087
E00-E07 Disorders of thyroid gland	0.912	0.088
H25.8 Other senile cataract	0.911	0.089
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.909	0.091
D05 Carcinoma in situ of breast	0.909	0.091
M80-M85 Disorders of bone density and structure	0.906	0.094
S02 Fracture of skull and facial bones	0.904	0.096
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.901	0.099
N17-N19 Renal failure	0.901	0.099
Chapter XXII Codes for special purposes	0.900	0.100
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.895	0.105
M23 Internal derangement of knee	0.893	0.107
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.890	0.110
H36 Retinal disorders in diseases classified elsewhere	0.888	0.111
M70-M79 Other soft tissue disorders	0.888	0.112
H02 Other disorders of eyelid	0.886	0.114
N21 Calculus of lower urinary tract	0.885	0.115
D70-D77 Other diseases of blood and blood-forming organs	0.882	0.118
N13.3 Other and unspecified hydronephrosis	0.882	0.118
K80 Cholelithiasis	0.879	0.121
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.878	0.122
N20.1 Calculus of ureter	0.877	0.123
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.870	0.130
H33 Retinal detachments and breaks	0.868	0.132
M50-M54 Other dorsopathies	0.866	0.134
H02.8 Other specified disorders of eyelid	0.866	0.134
G35-G37 Demyelinating diseases of the central nervous system	0.861	0.139
S40-S49 Injuries to the shoulder and upper arm	0.861	0.139
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.861	0.139
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.860	0.140
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.859	0.141
Chapter X Diseases of the respiratory system	0.859	0.141
E04 Other non-toxic goitre	0.857	0.143
H53 Visual disturbances	0.857	0.143
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.855	0.145
R91 Abnormal findings on diagnostic imaging of lung	0.855	0.145
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.853	0.147
I62 Other nontraumatic intracranial haemorrhage	0.852	0.148
S02.2 Fracture of nasal bones	0.849	0.151
E10 Insulin-dependent diabetes mellitus	0.849	0.151
J30-J39 Other diseases of upper respiratory tract	0.847	0.153
M24 Other specific joint derangements	0.847	0.153
M05-M14 Inflammatory polyarthropathies	0.845	0.155
H34 Retinal vascular occlusions	0.844	0.156
D05.9 Carcinoma in situ of breast, unspecified	0.843	0.157
D70 Agranulocytosis	0.842	0.158
H26 Other cataract	0.842	0.158
R22.0 Localised swelling, mass and lump, head	0.840	0.160
K70-K77 Diseases of liver	0.838	0.162
N20.2 Calculus of kidney with calculus of ureter	0.837	0.163
K80.2 Calculus of gallbladder without cholecystitis	0.837	0.163
K90-K93 Other diseases of the digestive system	0.836	0.164
R22.9 Localised swelling, mass and lump, unspecified	0.836	0.164
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.835	0.165
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.834	0.166
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.830	0.170
H35.8 Other specified retinal disorders	0.830	0.170
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.829	0.171
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.828	0.172
C51-C58 Malignant neoplasms of female genital organs	0.828	0.172
N00-N08 Glomerular diseases	0.826	0.174
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.824	0.176
R21 Rash and other nonspecific skin eruption	0.823	0.177
J32 Chronic sinusitis	0.822	0.178
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.819	0.181
G70-G73 Diseases of myoneural junction and muscle	0.818	0.182
S80-S89 Injuries to the knee and lower leg	0.818	0.182
K09 Cysts of oral region, not elsewhere classified	0.818	0.182
I78 Diseases of capillaries	0.817	0.183
I80 Phlebitis and thrombophlebitis	0.815	0.185
H46-H48 Disorders of optic nerve and visual pathways	0.813	0.187
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.812	0.188
I71 Aortic aneurysm and dissection	0.812	0.188
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.812	0.188
T66-T78 Other and unspecified effects of external causes	0.812	0.188
H35.2 Other proliferative retinopathy	0.811	0.189
H10-H13 Disorders of conjunctiva	0.811	0.189
M50 Cervical disk disorders	0.811	0.189
H02.4 Ptosis of eyelid	0.810	0.190
H36.0 Diabetic retinopathy	0.810	0.190
S02.20 Fracture of nasal bones (closed)	0.810	0.190
J30 Vasomotor and allergic rhinitis	0.809	0.191
N18 Chronic renal failure	0.809	0.191
H33.3 Retinal breaks without detachment	0.808	0.192
C91 Lymphoid leukaemia	0.807	0.193
N21.0 Calculus in bladder	0.807	0.193
K11 Diseases of salivary glands	0.807	0.193
B25-B34 Other viral diseases	0.804	0.196
I67 Other cerebrovascular diseases	0.803	0.197
M23.8 Other internal derangements of knee	0.802	0.198
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.800	0.200
D69 Purpura and other haemorrhagic conditions	0.797	0.203
B50-B64 Protozoal diseases	0.797	0.203
E05 Thyrotoxicosis [hyperthyroidism]	0.797	0.203
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.795	0.205
S42 Fracture of shoulder and upper arm	0.793	0.207
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.791	0.209
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.791	0.209
J32.9 Chronic sinusitis, unspecified	0.789	0.211
I74 Arterial embolism and thrombosis	0.786	0.214
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.785	0.215
E13 Other specified diabetes mellitus	0.785	0.215
N19 Unspecified renal failure	0.785	0.215
S06 Intracranial injury	0.784	0.216
T79-T79 Certain early complications of trauma	0.784	0.216
R94 Abnormal results of function studies	0.784	0.216
D04 Carcinoma in situ of skin	0.784	0.216
G90-G99 Other disorders of the nervous system	0.783	0.217
R22.2 Localised swelling, mass and lump, trunk	0.781	0.219
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.781	0.219
M79 Other soft tissue disorders, not elsewhere classified	0.778	0.222
B99-B99 Other infectious diseases	0.777	0.223
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.776	0.224
E04.2 Non-toxic multinodular goitre	0.776	0.224
H26.9 Cataract, unspecified	0.776	0.224
G35 Multiple sclerosis	0.774	0.226
M80 Osteoporosis with pathological fracture	0.774	0.226
H35.6 Retinal haemorrhage	0.774	0.226
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.773	0.227
K14 Diseases of tongue	0.773	0.227
E11 Non-insulin-dependent diabetes mellitus	0.772	0.228
E10.3 With ophthalmic complications	0.770	0.230
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.770	0.230
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.769	0.231
J30.1 Allergic rhinitis due to pollen	0.769	0.231
A50-A64 Infections with a predominantly sexual mode of transmission	0.769	0.231
G80-G83 Cerebral palsy and other paralytic syndromes	0.765	0.235
I65.2 Occlusion and stenosis of carotid artery	0.764	0.236
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.764	0.236
M50.1 Cervical disk disorder with radiculopathy	0.763	0.237
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.762	0.238
D69.6 Thrombocytopenia, unspecified	0.761	0.239
K05 Gingivitis and periodontal diseases	0.758	0.242
H18 Other disorders of cornea	0.757	0.243
M23.3 Other meniscus derangements	0.756	0.244
S02.1 Fracture of base of skull	0.756	0.244
Chapter VIII Diseases of the ear and mastoid process	0.756	0.244
E10.9 Without complications	0.755	0.245
D07 Carcinoma in situ of other and unspecified genital organs	0.755	0.245
R23 Other skin changes	0.755	0.245
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.750	0.250
D37-D48 Neoplasms of uncertain or unknown behaviour	0.750	0.250
T90 Sequelae of injuries of head	0.749	0.251
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.749	0.251
B20-B24 Human immunodeficiency virus [HIV] disease	0.749	0.251
M06 Other rheumatoid arthritis	0.749	0.251
C64-C68 Malignant neoplasms of urinary tract	0.747	0.253
R87 Abnormal findings in specimens from female genital organs	0.747	0.253
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.746	0.254
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.745	0.255
M91-M94 Chondropathies	0.745	0.255
H35.7 Separation of retinal layers	0.743	0.256
C54 Malignant neoplasm of corpus uteri	0.741	0.259
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.741	0.259
N10 Acute tubulo-interstitial nephritis	0.739	0.260
D55-D59 Haemolytic anaemias	0.739	0.261
G30-G32 Other degenerative diseases of the nervous system	0.739	0.261
U80 Agent resistant to penicillin and related antibiotics	0.739	0.261
E20-E35 Disorders of other endocrine glands	0.738	0.262
S70-S79 Injuries to the hip and thigh	0.738	0.262
D05.0 Lobular carcinoma in situ	0.737	0.262
M60-M63 Disorders of muscles	0.737	0.263
C83 Diffuse non-Hodgkin's lymphoma	0.736	0.264
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.736	0.264
M21 Other acquired deformities of limbs	0.734	0.266
M25 Other joint disorders, not elsewhere classified	0.733	0.267
N13.6 Pyonephrosis	0.733	0.267
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.732	0.268
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.731	0.269
N20.9 Urinary calculus, unspecified	0.730	0.270
D50-D53 Nutritional anaemias	0.729	0.271
G00-G09 Inflammatory diseases of the central nervous system	0.729	0.271
H53.4 Visual field defects	0.729	0.271
K07 Dentofacial anomalies [including malocclusion]	0.729	0.271
R22.3 Localised swelling, mass and lump, upper limb	0.729	0.271
B35-B49 Mycoses	0.728	0.272
M00-M03 Infectious arthropathies	0.727	0.273
H55-H59 Other disorders of eye and adnexa	0.727	0.273
K09.0 Developmental odontogenic cysts	0.726	0.274
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.726	0.274
H35.4 Peripheral retinal degeneration	0.726	0.274
K04 Diseases of pulp and periapical tissues	0.725	0.275
K12 Stomatitis and related lesions	0.725	0.275
R90 Abnormal findings on diagnostic imaging of central nervous system	0.725	0.275
C85.1 B-cell lymphoma, unspecified	0.725	0.275
M81 Osteoporosis without pathological fracture	0.722	0.278
B15-B19 Viral hepatitis	0.722	0.278
S02.9 Fracture of skull and facial bones, part unspecified	0.721	0.278
I69 Sequelae of cerebrovascular disease	0.721	0.279
I77 Other disorders of arteries and arterioles	0.721	0.279
D05.1 Intraductal carcinoma in situ	0.721	0.279
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.721	0.279
N11 Chronic tubulo-interstitial nephritis	0.721	0.279
M77 Other enthesopathies	0.720	0.280
U51 Admission status on psychiatric patients	0.719	0.280
N18.9 Chronic renal failure, unspecified	0.718	0.282
K92 Other diseases of digestive system	0.718	0.282
H04 Disorders of lachrymal system	0.717	0.283
M24.0 Loose body in joint	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.717	0.283
R22.1 Localised swelling, mass and lump, neck	0.717	0.283
E04.1 Non-toxic single thyroid nodule	0.716	0.284
H32 Chorioretinal disorders in diseases classified elsewhere	0.716	0.284
H31 Other disorders of choroid	0.716	0.284
H30 Chorioretinal inflammation	0.716	0.284
C15-C26 Malignant neoplasms of digestive organs	0.715	0.284
I00-I02 Acute rheumatic fever	0.713	0.286
I68 Cerebrovascular disorders in diseases classified elsewhere	0.713	0.286
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.713	0.286
E11.3 With ophthalmic complications	0.713	0.287
A30-A49 Other bacterial diseases	0.713	0.287
N22 Calculus of urinary tract in diseases classified elsewhere	0.713	0.287
T36-T50 Poisoning by drugs, medicaments and biological substances	0.713	0.287
M79.8 Other specified soft tissue disorders	0.713	0.287
B90-B94 Sequelae of infectious and parasitic diseases	0.712	0.288
B85-B89 Pediculosis, acariasis and other infestations	0.712	0.288
B65-B83 Helminthiases	0.712	0.288
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.712	0.288
A80-A89 Viral infections of the central nervous system	0.712	0.288
A75-A79 Rickettsioses	0.712	0.288
A70-A74 Other diseases caused by chlamydiae	0.712	0.288
A65-A69 Other spirochaetal diseases	0.712	0.288
A20-A28 Certain zoonotic bacterial diseases	0.712	0.288
A15-A19 Tuberculosis	0.712	0.288
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.711	0.289
H27 Other disorders of lens	0.711	0.289
S90-S99 Injuries to the ankle and foot	0.709	0.291
I86 Varicose veins of other sites	0.709	0.291
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
S82 Fracture of lower leg, including ankle	0.708	0.292
I67.8 Other specified cerebrovascular diseases	0.708	0.292
K70 Alcoholic liver disease	0.707	0.293
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.706	0.294
C40-C41 Malignant neoplasms of bone and articular cartilage	0.706	0.294
H35.9 Retinal disorder, unspecified	0.706	0.294
H35.5 Hereditary retinal dystrophy	0.706	0.294
H35.1 Retinopathy of prematurity	0.706	0.294
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.706	0.294
E05.9 Thyrotoxicosis, unspecified	0.705	0.294
M85 Other disorders of bone density and structure	0.705	0.295
H01 Other inflammation of eyelid	0.704	0.296
K72 Hepatic failure, not elsewhere classified	0.704	0.296
H25.2 Senile cataract, morgagnian type	0.703	0.297
H35.0 Background retinopathy and retinal vascular changes	0.703	0.297
I63.8 Other cerebral infarction	0.702	0.298
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.702	0.298
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.702	0.298
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.702	0.298
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.702	0.298
T15-T19 Effects of foreign body entering through natural orifice	0.701	0.299
T33-T35 Frostbite	0.701	0.299
T26-T28 Burns and corrosions confined to eye and internal organs	0.701	0.299
T20-T25 Burns and corrosions of external body surface, specified by site	0.701	0.299
T00-T07 Injuries involving multiple body regions	0.701	0.299
S10-S19 Injuries to the neck	0.701	0.299
M84 Disorders of continuity of bone	0.701	0.299
S50-S59 Injuries to the elbow and forearm	0.701	0.299
N18.5 Chronic kidney disease, stage 5	0.700	0.300
H53.9 Visual disturbance, unspecified	0.700	0.300
Chapter XX External causes of morbidity and mortality	0.700	0.300
N25-N29 Other disorders of kidney and ureter	0.699	0.301
K50-K52 Noninfective enteritis and colitis	0.699	0.301
G40-G47 Episodic and paroxysmal disorders	0.699	0.301
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.699	0.301
M65-M68 Disorders of synovium and tendon	0.697	0.302
H16 Keratitis	0.697	0.303
H53.0 Amblyopia ex anopsia	0.697	0.303
K11.5 Sialolithiasis	0.697	0.303
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.697	0.303
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.696	0.304
C95 Leukaemia of unspecified cell type	0.696	0.304
C94 Other leukaemias of specified cell type	0.696	0.304
C93 Monocytic leukaemia	0.696	0.304
C88 Malignant immunoproliferative diseases	0.696	0.304
C86 Other specified types of T/NK-cell lymphoma	0.696	0.304
C84 Peripheral and cutaneous T-cell lymphomas	0.696	0.304
D03 Melanoma in situ	0.696	0.304
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.304
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.696	0.304
J32.0 Chronic maxillary sinusitis	0.696	0.304
D80-D89 Certain disorders involving the immune mechanism	0.695	0.305
I78.1 Naevus, nonneoplastic	0.695	0.305
H02.5 Other disorders affecting eyelid function	0.694	0.306
M23.4 Loose body in knee	0.694	0.306
I95-I99 Other and unspecified disorders of the circulatory system	0.693	0.306
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.693	0.307
M86-M90 Other osteopathies	0.693	0.307
H34.8 Other retinal vascular occlusions	0.693	0.307
E13.9 Without complications	0.692	0.308
T92 Sequelae of injuries of upper limb	0.691	0.309
H11 Other disorders of conjunctiva	0.690	0.310
C81 Hodgkin's disease	0.690	0.310
S42.2 Fracture of upper end of humerus	0.689	0.311
M23.2 Derangement of meniscus due to old tear or injury	0.689	0.311
S01 Open wound of head	0.688	0.312
R87.6 Abnormal cytological findings	0.688	0.312
N13.4 Hydroureter	0.687	0.313
H05 Disorders of orbit	0.687	0.313
R47-R49 Symptoms and signs involving speech and voice	0.686	0.314
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.686	0.314
J09-J18 Influenza and pneumonia	0.686	0.314
D06 Carcinoma in situ of cervix uteri	0.685	0.315
D02 Carcinoma in situ of middle ear and respiratory system	0.684	0.316
D01 Carcinoma in situ of other and unspecified digestive organs	0.684	0.316
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.684	0.316
E40-E46 Malnutrition	0.684	0.316
I61 Intracerebral haemorrhage	0.683	0.317
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.682	0.318
N15 Other renal tubulo-interstitial diseases	0.682	0.318
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.682	0.318
M23.6 Other spontaneous disruption of ligament(s) of knee	0.681	0.319
R94.5 Abnormal results of liver function studies	0.680	0.320
C92 Myeloid leukaemia	0.680	0.320
H47 Other disorders of optic [2nd] nerve and visual pathways	0.680	0.320
M06.9 Rheumatoid arthritis, unspecified	0.680	0.320
C54.1 Endometrium	0.679	0.321
H53.8 Other visual disturbances	0.678	0.322
E07 Other disorders of thyroid	0.678	0.322
S42.3 Fracture of shaft of humerus	0.677	0.322
M50.0 Cervical disk disorder with myelopathy	0.677	0.323
I72 Other aneurysm	0.676	0.324
S02.6 Fracture of mandible	0.676	0.324
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.675	0.324
N08 Glomerular disorders in diseases classified elsewhere	0.675	0.325
C91.9 Lymphoid leukaemia, unspecified	0.674	0.326
M72 Fibroblastic disorders	0.674	0.326
S02.3 Fracture of orbital floor	0.674	0.326
H54 Blindness and low vision	0.674	0.326
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.673	0.327
N99-N99 Other disorders of the genitourinary system	0.672	0.327
G70 Myasthenia gravis and other myoneural disorders	0.672	0.328
S20-S29 Injuries to the thorax	0.672	0.328
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.672	0.328
K82 Other diseases of gallbladder	0.671	0.329
H34.2 Other retinal artery occlusions	0.671	0.329
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.669	0.331
M34 Systemic sclerosis	0.669	0.331
M33 Dermatopolymyositis	0.669	0.331
M32 Systemic lupus erythematosus	0.669	0.331
M30 Polyarteritis nodosa and related conditions	0.669	0.331
G62 Other polyneuropathies	0.668	0.332
H03 Disorders of eyelid in diseases classified elsewhere	0.668	0.332
R95-R99 Ill-defined and unknown causes of mortality	0.667	0.333
M24.8 Other specific joint derangements, not elsewhere classified	0.667	0.333
I70 Atherosclerosis	0.667	0.333
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.667	0.333
M24.1 Other articular cartilage disorders	0.667	0.333
S08 Traumatic amputation of part of head	0.666	0.334
S07 Crushing injury of head	0.666	0.334
S05 Injury of eye and orbit	0.666	0.334
S04 Injury of cranial nerves	0.666	0.334
S03 Dislocation, sprain and strain of joints and ligaments of head	0.666	0.334
C90 Multiple myeloma and malignant plasma cell neoplasms	0.664	0.336
N13.9 Obstructive and reflux uropathy, unspecified	0.664	0.336
N13.7 Vesicoureteral-reflux-associated uropathy	0.664	0.336
I85 Oesophageal varices	0.663	0.337
B25 Cytomegaloviral disease	0.663	0.337
G50-G59 Nerve, nerve root and plexus disorders	0.662	0.338
E11.2 With renal complications	0.661	0.338
E06 Thyroiditis	0.661	0.339
N18.4 Chronic kidney disease, stage 4	0.661	0.339
M35 Other systemic involvement of connective tissue	0.661	0.339
S82.6 Fracture of lateral malleolus	0.661	0.339
R45 Symptoms and signs involving emotional state	0.661	0.339
D72 Other disorders of white blood cells	0.659	0.341
K14.8 Other diseases of tongue	0.659	0.341
G99 Other disorders of nervous system in diseases classified elsewhere	0.659	0.341
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.659	0.341
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.659	0.341
D09 Carcinoma in situ of other and unspecified sites	0.658	0.342
S02.4 Fracture of malar and maxillary bones	0.657	0.343
K06 Other disorders of gingiva and edentulous alveolar ridge	0.657	0.343
K03 Other diseases of hard tissues of teeth	0.657	0.343
K00 Disorders of tooth development and eruption	0.657	0.343
E12 Malnutrition-related diabetes mellitus	0.656	0.343
I78.0 Hereditary haemorrhagic telangiectasia	0.656	0.344
R41 Other symptoms and signs involving cognitive functions and awareness	0.656	0.344
B59 Pneumocystosis	0.656	0.344
N13.5 Kinking and stricture of ureter without hydronephrosis	0.655	0.345
M31 Other necrotising vasculopathies	0.655	0.345
R22.7 Localised swelling, mass and lump, multiple sites	0.654	0.346
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.654	0.346
E00 Congenital iodine-deficiency syndrome	0.654	0.346
E02 Subclinical iodine-deficiency hypothyroidism	0.654	0.346
T78 Adverse effects, not elsewhere classified	0.654	0.346
K05.1 Chronic gingivitis	0.654	0.346
K10 Other diseases of jaws	0.654	0.346
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.653	0.347
I87 Other disorders of veins	0.653	0.347
E04.9 Non-toxic goitre, unspecified	0.652	0.348
C82.6 Cutaneous follicle centre lymphoma	0.652	0.348
C82.5 Diffuse follicle centre lymphoma	0.652	0.348
C82.4 Follicular lymphoma grade IIIb	0.652	0.348
C82.3 Follicular lymphoma grade IIIa	0.652	0.348
C82.2 Large cell, follicular	0.652	0.348
C82.1 Mixed small cleaved and large cell, follicular	0.652	0.348
C82.0 Small cleaved cell, follicular	0.652	0.348
T93 Sequelae of injuries of lower limb	0.652	0.348
R94.8 Abnormal results of function studies of other organs and systems	0.652	0.348
D05.7 Other carcinoma in situ of breast	0.652	0.348
S02.10 Fracture of base of skull (closed)	0.650	0.350
M83 Adult osteomalacia	0.650	0.350
M82 Osteoporosis in diseases classified elsewhere	0.650	0.350
K11.1 Hypertrophy of salivary gland	0.649	0.351
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.649	0.351
S02.8 Fractures of other skull and facial bones	0.648	0.352
S02.7 Multiple fractures involving skull and facial bones	0.648	0.352
S02.0 Fracture of vault of skull	0.648	0.352
S02.5 Fracture of tooth	0.648	0.352
M70 Soft tissue disorders related to use, overuse and pressure	0.647	0.353
I71.3 Abdominal aortic aneurysm, ruptured	0.647	0.353
K92.1 Melaena	0.647	0.353
C85.7 Other specified types of non-Hodgkin's lymphoma	0.646	0.354
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.646	0.354
C85.0 Lymphosarcoma	0.646	0.354
M24.2 Disorder of ligament	0.646	0.354
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.646	0.354
T79 Certain early complications of trauma, not elsewhere classified	0.645	0.355
N04 Nephrotic syndrome	0.644	0.355
G20-G26 Extrapyramidal and movement disorders	0.642	0.358
R92 Abnormal findings on diagnostic imaging of breast	0.642	0.358
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.642	0.358
K86 Other diseases of pancreas	0.642	0.358
G71 Primary disorders of muscles	0.641	0.359
M23.9 Internal derangement of knee, unspecified	0.641	0.359
M23.1 Discoid meniscus (congenital)	0.641	0.359
M23.0 Cystic meniscus	0.641	0.359
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.639	0.360
T68 Hypothermia	0.639	0.361
M80.9 Unspecified osteoporosis with pathological fracture	0.638	0.362
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.638	0.362
J40-J47 Chronic lower respiratory diseases	0.638	0.362
K91.4 Colostomy and enterostomy malfunction	0.637	0.363
H36.8 Other retinal disorders in diseases classified elsewhere	0.637	0.363
M76 Enthesopathies of lower limb, excluding foot	0.637	0.363
M73 Soft tissue disorders in diseases classified elsewhere	0.637	0.363
M71 Other bursopathies	0.637	0.363
G37 Other demyelinating diseases of central nervous system	0.636	0.364
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.636	0.364
H02.7 Other degenerative disorders of eyelid and periocular area	0.635	0.365
H02.2 Lagophthalmos	0.635	0.365
G61 Inflammatory polyneuropathy	0.635	0.365
T90.2 Sequelae of fracture of skull and facial bones	0.635	0.365
N21.9 Calculus of lower urinary tract, unspecified	0.635	0.365
N21.8 Other lower urinary tract calculus	0.635	0.365
N21.1 Calculus in urethra	0.635	0.365
U80.1 Methicillin resistant agent	0.635	0.365
D75 Other diseases of blood and blood-forming organs	0.634	0.366
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.633	0.366
K65-K67 Diseases of peritoneum	0.633	0.367
K09.8 Other cysts of oral region, not elsewhere classified	0.633	0.367
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.633	0.367
D74 Methaemoglobinaemia	0.633	0.367
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.633	0.367
D71 Functional disorders of polymorphonuclear neutrophils	0.633	0.367
K08 Other disorders of teeth and supporting structures	0.632	0.368
J30.3 Other allergic rhinitis	0.631	0.369
S80 Superficial injury of lower leg	0.631	0.369
H04.1 Other disorders of lachrymal gland	0.631	0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations