TreeWAS – Variant ID: rs4675248

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.300	0.700
E03 Other hypothyroidism	0.000	0.788	0.212
F31 Bipolar affective disorder	0.000	0.823	0.177
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.833	0.167
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.835	0.165
F30-F39 Mood [affective] disorders	0.000	0.836	0.164
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.836	0.164
F31.7 Bipolar affective disorder, currently in remission	0.000	0.839	0.161
F32 Depressive episode	0.000	0.845	0.155
F33 Recurrent depressive disorder	0.000	0.845	0.155
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.846	0.154
E03.5 Myxoedema coma	0.000	0.848	0.152
E03.4 Atrophy of thyroid (acquired)	0.000	0.848	0.152
E03.3 Postinfectious hypothyroidism	0.000	0.848	0.152
F33.9 Recurrent depressive disorder, unspecified	0.000	0.851	0.149
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.858	0.142
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.861	0.139
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.863	0.137
F32.1 Moderate depressive episode	0.000	0.864	0.136
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.866	0.134
E03.8 Other specified hypothyroidism	0.000	0.867	0.133
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.868	0.131
E03.1 Congenital hypothyroidism without goitre	0.000	0.872	0.128
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.872	0.128
F32.0 Mild depressive episode	0.000	0.872	0.128
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.872	0.127
F31.8 Other bipolar affective disorders	0.000	0.874	0.126
F34 Persistent mood [affective] disorders	0.000	0.877	0.123
F32.9 Depressive episode, unspecified	0.000	0.878	0.122
F38 Other mood [affective] disorders	0.000	0.879	0.121
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.883	0.117
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.886	0.114
F30 Manic episode	0.000	0.891	0.109
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.896	0.104
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.897	0.103
F39 Unspecified mood [affective] disorder	0.000	0.897	0.103
F31.9 Bipolar affective disorder, unspecified	0.000	0.897	0.103
F33.8 Other recurrent depressive disorders	0.000	0.900	0.100
F34.0 Cyclothymia	0.000	0.906	0.094
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.907	0.093
F32.8 Other depressive episodes	0.000	0.907	0.093
F38.0 Other single mood [affective] disorders	0.000	0.909	0.091
F30.1 Mania without psychotic symptoms	0.000	0.910	0.090
F34.1 Dysthymia	0.000	0.911	0.089
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.911	0.089
F34.8 Other persistent mood [affective] disorders	0.000	0.911	0.089
F38.1 Other recurrent mood [affective] disorders	0.000	0.913	0.087
F38.8 Other specified mood [affective] disorders	0.000	0.915	0.085
F30.8 Other manic episodes	0.000	0.922	0.078
F30.9 Manic episode, unspecified	0.000	0.925	0.075
F30.2 Mania with psychotic symptoms	0.000	0.925	0.074
F30.0 Hypomania	0.000	0.943	0.057
C71.9 Brain, unspecified	0.033	0.967	0.000
C71 Malignant neoplasm of brain	0.032	0.968	0.000
C71.0 Cerebrum, except lobes and ventricles	0.028	0.972	0.000
C71.3 Parietal lobe	0.027	0.973	0.000
C71.8 Overlapping lesion of brain	0.027	0.973	0.000
C71.2 Temporal lobe	0.027	0.973	0.000
C71.7 Brain stem	0.025	0.975	0.000
C71.4 Occipital lobe	0.025	0.975	0.000
C71.6 Cerebellum	0.025	0.975	0.000
C71.5 Cerebral ventricle	0.023	0.977	0.000
C71.1 Frontal lobe	0.021	0.979	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.989	0.011
Z50.8 Care involving use of rehabilitation procedures	0.010	0.990	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.991	0.009
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.009	0.991	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.992	0.008
R79.9 Abnormal finding of blood chemistry, unspecified	0.008	0.992	0.000
I71 Aortic aneurysm and dissection	0.000	0.992	0.008
K83.0 Cholangitis	0.000	0.993	0.007
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.007	0.993	0.000
I71.0 Dissection of aorta [any part]	0.000	0.993	0.007
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.993	0.007
S42.10 Fracture of scapula (closed)	0.000	0.993	0.007
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.993	0.007
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.993	0.007
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
S42.1 Fracture of scapula	0.000	0.994	0.006
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.994	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.006	0.994	0.000
S42 Fracture of shoulder and upper arm	0.000	0.994	0.006
C72.0 Spinal cord	0.006	0.994	0.000
S42.3 Fracture of shaft of humerus	0.000	0.994	0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.994	0.006
S42.4 Fracture of lower end of humerus	0.000	0.994	0.006
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.994	0.006
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.994	0.006
S42.40 Fracture of lower end of humerus (closed)	0.000	0.995	0.005
C72.9 Central nervous system, unspecified	0.005	0.995	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.005	0.995	0.000
C72.5 Other and unspecified cranial nerves	0.005	0.995	0.000
C72.4 Acoustic nerve	0.005	0.995	0.000
C72.3 Optic nerve	0.005	0.995	0.000
C72.2 Olfactory nerve	0.005	0.995	0.000
C72.1 Cauda equina	0.005	0.995	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.995	0.005
S42.2 Fracture of upper end of humerus	0.000	0.995	0.005
S42.20 Fracture of upper end of humerus (closed)	0.000	0.995	0.005
S42.31 Fracture of shaft of humerus (open)	0.000	0.995	0.005
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.995	0.005
B18.2 Chronic viral hepatitis C	0.000	0.995	0.005
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.995	0.005
E00-E07 Disorders of thyroid gland	0.000	0.995	0.005
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.995	0.005
S42.11 Fracture of scapula (open)	0.000	0.995	0.005
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.995	0.005
S42.41 Fracture of lower end of humerus (open)	0.000	0.995	0.005
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.995	0.005
U88 Agent resistant to multiple antibiotics	0.000	0.995	0.005
S65.1 Injury of radial artery at wrist and hand level	0.000	0.995	0.005
Z92.8 Personal history of other medical treatment	0.005	0.995	0.000
S65 Injury of blood vessels at wrist and hand level	0.000	0.995	0.005
C70.0 Cerebral meninges	0.004	0.996	0.000
S61 Open wound of wrist and hand	0.000	0.996	0.004
C69 Malignant neoplasm of eye and adnexa	0.004	0.996	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.996	0.004
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.996	0.004
S61.7 Multiple open wounds of wrist and hand	0.000	0.996	0.004
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.000	0.996	0.004
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.996	0.004
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.996	0.004
S65.5 Injury of blood vessel(s) of other finger	0.000	0.996	0.004
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.996	0.004
E00 Congenital iodine-deficiency syndrome	0.000	0.996	0.004
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.996	0.003
S42.21 Fracture of upper end of humerus (open)	0.000	0.996	0.003
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.996	0.003
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.996	0.003
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.996	0.003
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.996	0.003
S65.3 Injury of deep palmar arch	0.000	0.996	0.003
S65.2 Injury of superficial palmar arch	0.000	0.996	0.003
S42.0 Fracture of clavicle	0.000	0.996	0.003
S64.1 Injury of median nerve at wrist and hand level	0.000	0.996	0.003
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.997	0.003
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.997	0.003
S65.4 Injury of blood vessel(s) of thumb	0.000	0.997	0.003
B18 Chronic viral hepatitis	0.000	0.997	0.003
S64 Injury of nerves at wrist and hand level	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.003
C69.8 Overlapping lesion of eye and adnexa	0.003	0.997	0.000
C69.5 Lachrymal gland and duct	0.003	0.997	0.000
C69.4 Ciliary body	0.003	0.997	0.000
C69.1 Cornea	0.003	0.997	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.997	0.003
C69.0 Conjunctiva	0.003	0.997	0.000
C69.2 Retina	0.003	0.997	0.000
S60-S69 Injuries to the wrist and hand	0.000	0.997	0.003
S51.0 Open wound of elbow	0.003	0.997	0.000
L28.1 Prurigo nodularis	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
C69.6 Orbit	0.003	0.997	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.997	0.003
C69.9 Eye, unspecified	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.997	0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.997	0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.997	0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.997	0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.997	0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.997	0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.997	0.003
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.997	0.003
U89.9 Agent resistant to unspecified antibiotic	0.000	0.997	0.003
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
S42.01 Fracture of clavicle (open)	0.000	0.997	0.003
N83.0 Follicular cyst of ovary	0.003	0.997	0.000
S67 Crushing injury of wrist and hand	0.000	0.997	0.003
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
L28.0 Lichen simplex chronicus	0.000	0.997	0.003
U84 Resistance to other antimicrobial drugs	0.000	0.997	0.003
U83 Resistance to other antibiotics	0.000	0.997	0.003
U82 Resistance to betalactam antibiotics	0.000	0.997	0.003
U85 Resistance to antineoplastic drugs	0.000	0.997	0.003
B18.9 Chronic viral hepatitis, unspecified	0.000	0.997	0.003
B18.8 Other chronic viral hepatitis	0.000	0.997	0.003
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.997	0.003
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.997	0.003
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.997	0.003
S64.8 Injury of other nerves at wrist and hand level	0.000	0.997	0.003
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.997	0.003
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.997	0.003
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.997	0.003
S62.3 Fracture of other metacarpal bone	0.000	0.997	0.003
H81 Disorders of vestibular function	0.000	0.997	0.003
S62 Fracture at wrist and hand level	0.000	0.997	0.002
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
L28 Lichen simplex chronicus and prurigo	0.000	0.998	0.002
B17.8 Other specified acute viral hepatitis	0.000	0.998	0.002
B17.1 Acute hepatitis C	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.002
C69.3 Choroid	0.002	0.998	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.998	0.002
U82.8 Resistance to other betalactam antibiotics	0.000	0.998	0.002
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.998	0.002
U82.1 Resistance to methicillin	0.000	0.998	0.002
U82.0 Resistance to penicillin	0.000	0.998	0.002
U83.9 Resistance to unspecified antibiotic	0.000	0.998	0.002
U83.8 Resistance to other single specified antibiotic	0.000	0.998	0.002
U83.7 Resistance to multiple antibiotics	0.000	0.998	0.002
U83.2 Resistance to quinolones	0.000	0.998	0.002
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.998	0.002
U83.0 Resistance to vancomycin	0.000	0.998	0.002
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.998	0.002
U84.8 Resistance to other specified antimicrobial drug	0.000	0.998	0.002
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.998	0.002
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.998	0.002
U84.2 Resistance to antiviral drug(s)	0.000	0.998	0.002
U84.1 Resistance to antifungal drug(s)	0.000	0.998	0.002
U84.0 Resistance to antiparasitic drug(s)	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
S62.1 Fracture of other carpal bone(s)	0.000	0.998	0.002
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
L03.2 Cellulitis of face	0.002	0.998	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.998	0.002
E06 Thyroiditis	0.000	0.998	0.002
B17.9 Acute viral hepatitis, unspecified	0.000	0.998	0.002
B17.2 Acute hepatitis E	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.000	0.998	0.002
B15-B19 Viral hepatitis	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.998	0.002
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.998	0.002
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.998	0.002
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.998	0.002
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.998	0.002
S68.4 Traumatic amputation of hand at wrist level	0.000	0.998	0.002
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.998	0.002
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.000	0.998	0.002
S62.21 Fracture of first metacarpal bone (open)	0.000	0.998	0.002
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.998	0.002
E07 Other disorders of thyroid	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.000	0.998	0.002
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
S63.0 Dislocation of wrist	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.998	0.002
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.998	0.002
L28.2 Other prurigo	0.000	0.998	0.002
R44.3 Hallucinations, unspecified	0.000	0.998	0.002
B16 Acute hepatitis B	0.000	0.998	0.002
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.002
E06.0 Acute thyroiditis	0.000	0.998	0.002
Q05 Spina bifida	0.002	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.998	0.002
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
S62.5 Fracture of thumb	0.000	0.998	0.002
I89.1 Lymphangitis	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
S62.4 Multiple fractures of metacarpal bones	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.000	0.998	0.001
I45.3 Trifascicular block	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.998	0.002
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.000	0.998	0.001
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.001
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
S42.00 Fracture of clavicle (closed)	0.000	0.998	0.002
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
N32.1 Vesicointestinal fistula	0.002	0.998	0.000
K25.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.998	0.001
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
S69.7 Multiple injuries of wrist and hand	0.000	0.998	0.001
B15 Acute hepatitis A	0.000	0.998	0.001
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.998	0.001
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.998	0.001
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.998	0.001
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
R14 Flatulence and related conditions	0.000	0.998	0.002
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.998	0.000
S63.1 Dislocation finger	0.000	0.998	0.001
S63.2 Multiple dislocations of fingers	0.000	0.998	0.001
D36.7 Other specified sites	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.998	0.001
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
B19 Unspecified viral hepatitis	0.000	0.998	0.001
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.001
Q07.8 Other specified congenital malformations of nervous system	0.001	0.998	0.000
I45.5 Other specified heart block	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.001	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.998	0.001
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.001
D38.1 Trachea, bronchus and lung	0.001	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.001	0.998	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.001
Q03.0 Malformations of aqueduct of Sylvius	0.001	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.000	0.998	0.001
Q03 Congenital hydrocephalus	0.001	0.999	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.999	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.999	0.001
S69.8 Other specified injuries of wrist and hand	0.000	0.999	0.001
Chapter XXII Codes for special purposes	0.000	0.999	0.001
B15.0 Hepatitis A with hepatic coma	0.000	0.999	0.001
R44.0 Auditory hallucinations	0.000	0.999	0.001
Q06 Other congenital malformations of spinal cord	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.999	0.001
E06.9 Thyroiditis, unspecified	0.000	0.999	0.001
I89.0 Lymphoedema, not elsewhere classified	0.000	0.999	0.001
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.001	0.999	0.000
K09.0 Developmental odontogenic cysts	0.001	0.999	0.000
N48.8 Other specified disorders of penis	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
D36 Benign neoplasm of other and unspecified sites	0.001	0.999	0.000
B19.0 Unspecified viral hepatitis with coma	0.000	0.999	0.001
N15.1 Renal and perinephric abscess	0.000	0.999	0.001
Q06.8 Other specified congenital malformations of spinal cord	0.001	0.999	0.000
Q76.0 Spina bifida occulta	0.000	0.999	0.001
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
H11.0 Pterygium	0.000	0.999	0.001
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.999	0.001
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.999	0.001
S63.5 Sprain and strain of wrist	0.000	0.999	0.001
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.999	0.001
H65.4 Other chronic nonsuppurative otitis media	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.999	0.001
N15.0 Balkan nephropathy	0.000	0.999	0.001
Q03.9 Congenital hydrocephalus, unspecified	0.001	0.999	0.000
Q03.8 Other congenital hydrocephalus	0.001	0.999	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.001	0.999	0.000
W25.9 Unspecified place	0.001	0.999	0.000
Q01 Encephalocele	0.001	0.999	0.000
Q00 Anencephaly and similar malformations	0.001	0.999	0.000
Q02 Microcephaly	0.001	0.999	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.999	0.001
T42.1 Iminostilbenes	0.000	0.999	0.001
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.999	0.001
Q06.2 Diastematomyelia	0.001	0.999	0.000
U80.0 Penicillin resistant agent	0.000	0.999	0.001
Q04 Other congenital malformations of brain	0.001	0.999	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.999	0.000
E07.8 Other specified disorders of thyroid	0.000	0.999	0.001
Q06.9 Congenital malformation of spinal cord, unspecified	0.001	0.999	0.000
Q06.4 Hydromyelia	0.001	0.999	0.000
Q06.3 Other congenital cauda equina malformations	0.001	0.999	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.001	0.999	0.000
Q06.0 Amyelia	0.001	0.999	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.999	0.001
D36.9 Benign neoplasm of unspecified site	0.001	0.999	0.000
D36.0 Lymph nodes	0.001	0.999	0.000
R44.2 Other hallucinations	0.000	0.999	0.001
E04 Other non-toxic goitre	0.000	0.999	0.001
R06.8 Other and unspecified abnormalities of breathing	0.001	0.999	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.999	0.001
B15.9 Hepatitis A without hepatic coma	0.000	0.999	0.001
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.999	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.999	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.999	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.999	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.999	0.001
G63.1 Polyneuropathy in neoplastic disease	0.000	0.999	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.999	0.001
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.999	0.001
Q00.2 Iniencephaly	0.001	0.999	0.000
Q00.1 Craniorachischisis	0.001	0.999	0.000
Q00.0 Anencephaly	0.001	0.999	0.000
Q01.9 Encephalocele, unspecified	0.001	0.999	0.000
Q01.8 Encephalocele of other sites	0.001	0.999	0.000
Q01.2 Occipital encephalocele	0.001	0.999	0.000
Q01.1 Nasofrontal encephalocele	0.001	0.999	0.000
Q01.0 Frontal encephalocele	0.001	0.999	0.000
T20.1 Burn of first degree of head and neck	0.001	0.999	0.000
Q04.9 Congenital malformation of brain, unspecified	0.001	0.999	0.000
Q04.8 Other specified congenital malformations of brain	0.001	0.999	0.000
Q04.5 Megalencephaly	0.001	0.999	0.000
Q04.4 Septo-optic dysplasia	0.001	0.999	0.000
Q04.3 Other reduction deformities of brain	0.001	0.999	0.000
Q04.2 Holoprosencephaly	0.001	0.999	0.000
Q04.1 Arhinencephaly	0.001	0.999	0.000
Q04.0 Congenital malformations of corpus callosum	0.001	0.999	0.000
S51 Open wound of forearm	0.001	0.999	0.000
N94.5 Secondary dysmenorrhoea	0.000	0.999	0.001
T42.0 Hydantoin derivatives	0.000	0.999	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.999	0.001
E04.8 Other specified non-toxic goitre	0.000	0.999	0.001
H83.8 Other specified diseases of inner ear	0.000	0.999	0.001
N64.1 Fat necrosis of breast	0.000	0.999	0.001
Q04.6 Congenital cerebral cysts	0.001	0.999	0.000
S51.9 Open wound of forearm, part unspecified	0.001	0.999	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.999	0.001
B19.9 Unspecified viral hepatitis without coma	0.000	0.999	0.001
N48.2 Other inflammatory disorders of penis	0.000	0.999	0.001
R63.1 Polydipsia	0.001	0.999	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.999	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.999	0.001
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
L29.9 Pruritus, unspecified	0.000	0.999	0.001
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.999	0.001
B25.9 Cytomegaloviral disease, unspecified	0.001	0.999	0.000
I42.0 Dilated cardiomyopathy	0.000	0.999	0.001
I45.8 Other specified conduction disorders	0.001	0.999	0.000
L13.0 Dermatitis herpetiformis	0.001	0.999	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.999	0.001
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.000	0.999	0.001
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.999	0.001
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.999	0.001
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.999	0.001
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.999	0.001
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.999	0.001
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.999	0.001
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.999	0.001
O03.4 Incomplete, without complication	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
T42.4 Benzodiazepines	0.000	0.999	0.001
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.999	0.001
S60 Superficial injury of wrist and hand	0.000	0.999	0.001
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.999	0.001
U50 Level of care administered to neonates	0.000	0.999	0.001
U07 Emergency use of U07	0.000	0.999	0.001
U06 Emergency use of U06	0.000	0.999	0.001
U04 Severe acute respiratory syndrome [SARS]	0.000	0.999	0.001
U52 First in a series of a regular day/night admissions	0.000	0.999	0.001
I45.0 Right fascicular block	0.001	0.999	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
M24.66 Ankylosis of joint (Lower leg)	0.000	0.999	0.001
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.999	0.001
S62.51 Fracture of thumb (open)	0.000	0.999	0.001
D48.0 Bone and articular cartilage	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.000	0.999	0.001
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.999	0.001
R41.0 Disorientation, unspecified	0.000	0.999	0.001
S61.1 Open wound of finger(s) with damage to nail	0.000	0.999	0.001
T79.9 Unspecified early complication of trauma	0.000	0.999	0.001
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.999	0.001
T79.1 Fat embolism (traumatic)	0.000	0.999	0.001
T79.0 Air embolism (traumatic)	0.000	0.999	0.001
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.999	0.001
U80 Agent resistant to penicillin and related antibiotics	0.000	0.999	0.001
M91.20 Coxa plana-Mult sites	0.001	0.999	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.999	0.001
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.999	0.001
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.999	0.001
N14.3 Nephropathy induced by heavy metals	0.000	0.999	0.001
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.999	0.001
N14.0 Analgesic nephropathy	0.000	0.999	0.001
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.999	0.001
U06.9 Emergency use of U06.9	0.000	0.999	0.001
U06.8 Emergency use of U06.8	0.000	0.999	0.001
U06.7 Emergency use of U06.7	0.000	0.999	0.001
U06.6 Emergency use of U06.6	0.000	0.999	0.001
U06.5 Emergency use of U06.5	0.000	0.999	0.001
U06.4 Emergency use of U06.4	0.000	0.999	0.001
U06.3 Emergency use of U06.3	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations