TreeWAS – Variant ID: rs4681767

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.963	0.037
S22.40 Multiple fractures of ribs (closed)	0.000	0.966	0.034
K60.2 Anal fissure, unspecified	0.034	0.966	0.000
S29.9 Unspecified injury of thorax	0.000	0.971	0.029
S22.4 Multiple fractures of ribs	0.000	0.973	0.027
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.026	0.974	0.000
S29 Other and unspecified injuries of thorax	0.000	0.974	0.026
S20-S29 Injuries to the thorax	0.000	0.977	0.023
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.022	0.978	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.978	0.022
N11 Chronic tubulo-interstitial nephritis	0.022	0.978	0.000
N10-N16 Renal tubulo-interstitial diseases	0.022	0.978	0.000
N10 Acute tubulo-interstitial nephritis	0.021	0.979	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.979	0.021
G91.9 Hydrocephalus, unspecified	0.000	0.980	0.020
S22.41 Multiple fractures of ribs (open)	0.000	0.980	0.020
S20 Superficial injury of thorax	0.000	0.980	0.020
S29.8 Other specified injuries of thorax	0.000	0.981	0.019
S29.7 Multiple injuries of thorax	0.000	0.981	0.019
S27.0 Traumatic pneumothorax	0.000	0.981	0.018
S29.0 Injury of muscle and tendon at thorax level	0.000	0.982	0.018
N11.1 Chronic obstructive pyelonephritis	0.018	0.982	0.000
N15 Other renal tubulo-interstitial diseases	0.018	0.982	0.000
S24 Injury of nerves and spinal cord at thorax level	0.000	0.983	0.017
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.983	0.017
S26 Injury of heart	0.000	0.983	0.017
S25 Injury of blood vessels of thorax	0.000	0.983	0.017
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.983	0.017
K60 Fissure and fistula of anal and rectal regions	0.017	0.983	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.983	0.017
S27.2 Traumatic heamopneumothorax	0.000	0.984	0.016
S22.9 Fracture of bony thorax, part unspecified	0.000	0.984	0.016
S22.8 Fracture of other parts of bony thorax	0.000	0.984	0.016
N11.8 Other chronic tubulo-interstitial nephritis	0.016	0.984	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.016	0.984	0.000
S22.3 Fracture of rib	0.000	0.984	0.016
S20.0 Contusion of breast	0.000	0.984	0.016
S27.1 Traumatic haemothorax	0.000	0.984	0.016
S20.3 Other superficial injuries of front wall of thorax	0.000	0.984	0.016
K60.1 Chronic anal fissure	0.016	0.984	0.000
S21 Open wound of thorax	0.000	0.984	0.015
S27.9 Injury of unspecified intrathoracic organ	0.000	0.985	0.015
S27.7 Multiple injuries of intrathoracic organs	0.000	0.985	0.015
S27.6 Injury of pleura	0.000	0.985	0.015
S27.5 Injury of thoracic trachea	0.000	0.985	0.015
S27.4 Injury of bronchus	0.000	0.985	0.015
S20.1 Other and unspecified superficial injuries of breast	0.000	0.985	0.015
S20.2 Contusion of thorax	0.000	0.985	0.015
N15.1 Renal and perinephric abscess	0.015	0.985	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.015	0.985	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.015	0.985	0.000
S27.3 Other injuries of lung	0.000	0.985	0.015
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.985	0.015
S27.8 Injury of other specified intrathoracic organs	0.000	0.985	0.014
K60.4 Rectal fistula	0.015	0.985	0.000
S22.5 Flail chest	0.000	0.986	0.014
S22.1 Multiple fractures of thoracic spine	0.000	0.986	0.014
K60.5 Anorectal fistula	0.014	0.986	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.986	0.013
S20.7 Multiple superficial injuries of thorax	0.000	0.987	0.013
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.987	0.013
N15.8 Other specified renal tubulo-interstitial diseases	0.013	0.987	0.000
N15.0 Balkan nephropathy	0.013	0.987	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.987	0.012
S24.6 Injury of unspecified nerve of thorax	0.000	0.987	0.012
S24.5 Injury of other nerves of thorax	0.000	0.987	0.012
S24.4 Injury of thoracic sympathetic nerves	0.000	0.987	0.012
S24.3 Injury of peripheral nerves of thorax	0.000	0.987	0.012
S24.2 Injury of nerve root of thoracic spine	0.000	0.987	0.012
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.987	0.012
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.987	0.012
S23.4 Sprain and strain of ribs and sternum	0.000	0.987	0.012
S23.3 Sprain and strain of thoracic spine	0.000	0.987	0.012
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.987	0.012
S23.1 Dislocation of thoracic vertebra	0.000	0.987	0.012
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.987	0.012
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.987	0.012
S25.8 Injury of other blood vessels of thorax	0.000	0.987	0.012
S25.7 Injury of multiple blood vessels of thorax	0.000	0.987	0.012
S25.5 Injury of intercostal blood vessels	0.000	0.987	0.012
S25.4 Injury of pulmonary blood vessels	0.000	0.987	0.012
S25.3 Injury of innominate or subclavian vein	0.000	0.987	0.012
S25.2 Injury of superior vena cava	0.000	0.987	0.012
S25.1 Injury of innominate or subclavian artery	0.000	0.987	0.012
S25.0 Injury of thoracic aorta	0.000	0.987	0.012
S26.9 Injury of heart, unspecified	0.000	0.987	0.012
S26.8 Other injuries of heart	0.000	0.987	0.012
S26.0 Injury of heart with haemopericardium	0.000	0.987	0.012
S28.1 Traumatic amputation of part of thorax	0.000	0.987	0.012
S28.0 Crushed chest	0.000	0.987	0.012
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.988	0.012
N15.9 Renal tubulo-interstitial disease, unspecified	0.012	0.988	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.012	0.988	0.000
S22.2 Fracture of sternum	0.000	0.988	0.012
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.988	0.012
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.988	0.012
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.988	0.012
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.988	0.012
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.988	0.012
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.012	0.988	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.012	0.988	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.012	0.988	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.012	0.988	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.012	0.988	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.012	0.988	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
S22.31 Fracture of rib (open)	0.000	0.988	0.012
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.988	0.012
S20.4 Other superficial injuries of back wall of thorax	0.000	0.988	0.011
S21.9 Open wound of thorax, part unspecified	0.000	0.988	0.011
S21.8 Open wound of other parts of thorax	0.000	0.989	0.011
S21.7 Multiple open wounds of thoracic wall	0.000	0.989	0.011
S21.2 Open wound of back wall of thorax	0.000	0.989	0.011
S21.0 Open wound of breast	0.000	0.989	0.011
S22.30 Fracture of rib (closed)	0.000	0.989	0.011
T88.7 Unspecified adverse effect of drug or medicament	0.011	0.989	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.989	0.011
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.989	0.011
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.989	0.011
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.989	0.011
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.989	0.011
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.989	0.011
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.989	0.011
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.989	0.011
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.989	0.011
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.989	0.011
N14.4 Toxic nephropathy, not elsewhere classified	0.011	0.989	0.000
N14.3 Nephropathy induced by heavy metals	0.011	0.989	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.011	0.989	0.000
N14.0 Analgesic nephropathy	0.011	0.989	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.989	0.011
G91 Hydrocephalus	0.000	0.989	0.011
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.989	0.011
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.989	0.010
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.989	0.010
S22.51 Flail chest (open)	0.000	0.989	0.010
K76.0 Fatty (change of) liver, not elsewhere classified	0.011	0.989	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.990	0.010
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.990	0.010
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.990	0.010
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.010	0.990	0.000
S21.1 Open wound of front wall of thorax	0.000	0.990	0.010
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.991	0.009
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.991	0.009
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.991	0.009
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.000	0.991	0.009
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.991	0.009
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.991	0.009
S22.21 Fracture of sternum (open)	0.000	0.991	0.009
G91.8 Other hydrocephalus	0.000	0.991	0.009
G91.2 Normal-pressure hydrocephalus	0.000	0.991	0.009
M79.65 Pain in limb (Pelvic region and thigh)	0.009	0.991	0.000
T88.4 Failed or difficult intubation	0.009	0.991	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.009	0.991	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.009	0.991	0.000
K60.0 Acute anal fissure	0.008	0.991	0.000
S22.50 Flail chest (closed)	0.000	0.991	0.008
G91.0 Communicating hydrocephalus	0.000	0.992	0.008
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.992	0.008
S22.01 Fracture of thoracic vertebra (open)	0.000	0.992	0.008
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.992	0.008
I70.0 Atherosclerosis of aorta	0.007	0.993	0.000
T88.9 Complication of surgical and medical care, unspecified	0.007	0.993	0.000
G91.1 Obstructive hydrocephalus	0.000	0.993	0.007
T88.2 Shock due to anaesthesia	0.007	0.993	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.007	0.993	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.007	0.993	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.006	0.993	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.006	0.993	0.000
T88.0 Infection following immunisation	0.006	0.993	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
I70 Atherosclerosis	0.006	0.994	0.000
W55.0 Home	0.006	0.994	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.005	0.994	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.005	0.995	0.000
I70.8 Atherosclerosis of other arteries	0.005	0.995	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.995	0.005
T88.5 Other complications of anaesthesia	0.005	0.995	0.000
S22.20 Fracture of sternum (closed)	0.000	0.995	0.005
Q87.4 Marfan's syndrome	0.000	0.995	0.005
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.004	0.995	0.000
H40.0 Glaucoma suspect	0.000	0.995	0.005
F06.7 Mild cognitive disorder	0.000	0.996	0.004
C16.9 Stomach, unspecified	0.004	0.996	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
I70.9 Generalised and unspecified atherosclerosis	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.000	0.996	0.004
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.996	0.000
Z99.8 Dependence on other enabling machines and devices	0.004	0.996	0.000
W55 Bitten or struck by other mammals	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.003	0.996	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.004	0.996	0.000
C16.0 Cardia	0.004	0.996	0.000
I72.4 Aneurysm of artery of lower extremity	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.004	0.996	0.000
W44.0 Home	0.000	0.997	0.003
I72 Other aneurysm	0.003	0.997	0.000
W55.4 Street and highway	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.003	0.997	0.000
I72.8 Aneurysm of other specified arteries	0.003	0.997	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.003	0.997	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.997	0.003
K86 Other diseases of pancreas	0.000	0.997	0.003
W55.7 Farm	0.003	0.997	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.003	0.997	0.000
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
I72.0 Aneurysm of carotid artery	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.000	0.997	0.003
K26.5 Chronic or unspecified with perforation	0.003	0.997	0.000
C16.4 Pylorus	0.003	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
I73.9 Peripheral vascular disease, unspecified	0.003	0.997	0.000
W55.9 Unspecified place	0.003	0.997	0.000
W55.5 Trade and service area	0.003	0.997	0.000
W55.6 Industrial and construction area	0.003	0.997	0.000
W55.3 Sports and athletics area	0.003	0.997	0.000
W55.2 School, other institution and public administrative area	0.003	0.997	0.000
W55.1 Residential institution	0.003	0.997	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
I72.2 Aneurysm of renal artery	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
I72.9 Aneurysm of unspecified site	0.003	0.997	0.000
W55.8 Other specified place	0.003	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.997	0.003
C16.1 Fundus of stomach	0.003	0.997	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
C16.2 Body of stomach	0.003	0.997	0.000
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.003	0.997	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.003	0.997	0.000
N42.1 Congestion and haemorrhage of prostate	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.003	0.997	0.000
Z37.2 Twins, both liveborn	0.000	0.997	0.003
Z48.0 Attention to surgical dressings and sutures	0.003	0.997	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.997	0.003
I73 Other peripheral vascular diseases	0.003	0.997	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.003	0.997	0.000
I72.1 Aneurysm of artery of upper extremity	0.002	0.997	0.000
K60.3 Anal fistula	0.002	0.997	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.998	0.002
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.002	0.998	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.002	0.998	0.000
C16.3 Pyloric antrum	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.998	0.002
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
I13 Hypertensive heart and renal disease	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.000	0.998	0.002
D41.0 Kidney	0.002	0.998	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
I78 Diseases of capillaries	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
I15 Secondary hypertension	0.000	0.998	0.002
S02.5 Fracture of tooth	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.000	0.998	0.002
I11 Hypertensive heart disease	0.000	0.998	0.002
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.002
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.998	0.002
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.998	0.002
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.002	0.998	0.000
I78.8 Other diseases of capillaries	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.998	0.000
M43.1 Spondylolisthesis	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.000	0.998	0.002
I20.8 Other forms of angina pectoris	0.000	0.998	0.002
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.998	0.001
Z99.3 Dependence on wheelchair	0.002	0.998	0.000
Z99.0 Dependence on aspirator	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.998	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.002	0.998	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.002	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.000	0.998	0.001
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
H34.1 Central retinal artery occlusion	0.000	0.998	0.002
L60.9 Nail disorder, unspecified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
K76 Other diseases of liver	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
Z99.4 Dependence on artificial heart	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.998	0.001
I15.0 Renovascular hypertension	0.000	0.998	0.001
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
K76.3 Infarction of liver	0.002	0.998	0.000
I15.8 Other secondary hypertension	0.000	0.998	0.001
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.001
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.001	0.998	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.001	0.998	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.001	0.998	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.001	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
E13.9 Without complications	0.002	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.001	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.002	0.998	0.000
S72.0 Fracture of neck of femur	0.000	0.998	0.002
Z99.9 Dependence on unspecified enabling machine and device	0.001	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.001	0.998	0.000
K76.7 Hepatorenal syndrome	0.002	0.998	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.001	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.001	0.998	0.000
G80.8 Other infantile cerebral palsy	0.001	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.001	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.001	0.998	0.000
Q54.9 Hypospadias, unspecified	0.000	0.998	0.001
D33.3 Cranial nerves	0.000	0.998	0.002
K62.5 Haemorrhage of anus and rectum	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.001
S02.6 Fracture of mandible	0.001	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.001
W44 Foreign body entering into or through eye or natural orifice	0.000	0.998	0.001
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.999	0.001
M89.87 Other specified disorders of bone (Ankle and foot)	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.001	0.999	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
K76.5 Hepatic veno-occlusive disease	0.001	0.999	0.000
K76.4 Peliosis hepatis	0.001	0.999	0.000
K76.2 Central haemorrhagic necrosis of liver	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
I62.1 Nontraumatic extradural haemorrhage	0.001	0.999	0.000
R73.0 Abnormal glucose tolerance test	0.001	0.999	0.000
Z99.2 Dependence on renal dialysis	0.001	0.999	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.999	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.999	0.001
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.999	0.001
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.999	0.001
Y54.3 Benzothiadiazine derivatives	0.000	0.999	0.001
S72.01 Fracture of neck of femur (open)	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
G80 Infantile cerebral palsy	0.001	0.999	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.001	0.999	0.000
Z99.1 Dependence on respirator	0.001	0.999	0.000
K76.1 Chronic passive congestion of liver	0.001	0.999	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
D39.1 Ovary	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.001	0.999	0.000
S89.8 Other specified injuries of lower leg	0.001	0.999	0.000
H34 Retinal vascular occlusions	0.000	0.999	0.001
L56 Other acute skin changes due to ultraviolet radiation	0.001	0.999	0.000
S02.61 Fracture of mandible (open)	0.001	0.999	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
G80.0 Spastic cerebral palsy	0.001	0.999	0.000
J39.2 Other diseases of pharynx	0.001	0.999	0.000
L60.3 Nail dystrophy	0.001	0.999	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.999	0.001
W44.9 Unspecified place	0.000	0.999	0.001
W44.5 Trade and service area	0.000	0.999	0.001
W44.7 Farm	0.000	0.999	0.001
W44.6 Industrial and construction area	0.000	0.999	0.001
W44.4 Street and highway	0.000	0.999	0.001
W44.3 Sports and athletics area	0.000	0.999	0.001
W44.2 School, other institution and public administrative area	0.000	0.999	0.001
W44.1 Residential institution	0.000	0.999	0.001
S02.21 Fracture of nasal bones (open)	0.001	0.999	0.000
D09.0 Bladder	0.001	0.999	0.000
L56.4 Polymorphous light eruption	0.001	0.999	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.001	0.999	0.000
S02.01 Fracture of vault of skull (open)	0.001	0.999	0.000
S02.60 Fracture of mandible (closed)	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.999	0.001
F06.5 Organic dissociative disorder	0.000	0.999	0.001
F06.4 Organic anxiety disorder	0.000	0.999	0.001
F06.1 Organic catatonic disorder	0.000	0.999	0.001
F06.0 Organic hallucinosis	0.000	0.999	0.001
I71.1 Thoracic aortic aneurysm, ruptured	0.001	0.999	0.000
I77.6 Arteritis, unspecified	0.001	0.999	0.000
K14.9 Disease of tongue, unspecified	0.000	0.999	0.001
M70.6 Trochanteric bursitis	0.000	0.999	0.001
I62 Other nontraumatic intracranial haemorrhage	0.001	0.999	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.999	0.001
M19.94 Arthrosis, unspecified (Hand)	0.000	0.999	0.001
M43.12 Spondylolisthesis (Cervical region)	0.001	0.999	0.000
G80.4 Ataxic cerebral palsy	0.001	0.999	0.000
G80.3 Dyskinetic cerebral palsy	0.001	0.999	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.999	0.001
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.999	0.001
E10.5 With peripheral circulatory complications	0.000	0.999	0.001
G53.0 Postzoster neuralgia	0.000	0.999	0.001
S40.0 Contusion of shoulder and upper arm	0.000	0.999	0.001
T83.2 Mechanical complication of graft of urinary organ	0.001	0.999	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.001	0.999	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.001	0.999	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.999	0.001
L56.3 Solar urticaria	0.001	0.999	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.001	0.999	0.000
L56.1 Drug photoallergic response	0.001	0.999	0.000
L56.0 Drug phototoxic response	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.000	0.999	0.001
S02.8 Fractures of other skull and facial bones	0.001	0.999	0.000
T85.2 Mechanical complication of intraocular lens	0.001	0.999	0.000
W44.8 Other specified place	0.000	0.999	0.001
W44.59 Foreign body entering into or through eye or natural orifice; Trade and service area;During unspecified activity	0.000	0.999	0.001
W44.99 Foreign body entering into or through eye or natural orifice, Unspecified place , During unspecified activity	0.000	0.999	0.001
H34.0 Transient retinal artery occlusion	0.000	0.999	0.001
R94.6 Abnormal results of thyroid function studies	0.001	0.999	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
M70.68 Trochanteric bursitis-Other	0.000	0.999	0.001
M70.67 Trochanteric bursitis-Ankle/Foot	0.000	0.999	0.001
M70.66 Trochanteric bursitis-Lower Leg	0.000	0.999	0.001
M70.64 Trochanteric bursitis-Hand	0.000	0.999	0.001
M70.63 Trochanteric bursitis-Forearm	0.000	0.999	0.001
M70.62 Trochanteric bursitis-Upper arm	0.000	0.999	0.001
M70.61 Trochanteric bursitis-Shldr region	0.000	0.999	0.001
M70.60 Trochanteric bursitis-Mult sites	0.000	0.999	0.001
M79.19 Myalgia (Site unspecified)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
E55.9 Vitamin D deficiency, unspecified	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.000	0.999	0.001
K10.2 Inflammatory conditions of jaws	0.001	0.999	0.000
M70.69 Trochanteric bursitis-Site unspec	0.000	0.999	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.999	0.001
G24.5 Blepharospasm	0.001	0.999	0.000
J15.4 Pneumonia due to other streptococci	0.001	0.999	0.000
W01.1 Residential institution	0.001	0.999	0.000
G80.9 Infantile cerebral palsy, unspecified	0.001	0.999	0.000
N75.0 Cyst of Bartholin's gland	0.001	0.999	0.000
S02.2 Fracture of nasal bones	0.001	0.999	0.000
B99 Other and unspecified infectious diseases	0.001	0.999	0.000
J81 Pulmonary oedema	0.001	0.999	0.000
S02.81 Fractures of other skull and facial bones (open)	0.001	0.999	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.999	0.001
S81.9 Open wound of lower leg, part unspecified	0.000	0.999	0.001
M79.10 Myalgia (Multiple sites)	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.999	0.001
E83.3 Disorders of phosphorus metabolism	0.000	0.999	0.001
F41.1 Generalised anxiety disorder	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.000	0.999	0.001
Z04.3 Examination and observation following other accident	0.001	0.999	0.000
Z71.9 Counselling, unspecified	0.001	0.999	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001
I15.1 Hypertension secondary to other renal disorders	0.000	0.999	0.001
I46.0 Cardiac arrest with successful resuscitation	0.000	0.999	0.001
J84.9 Interstitial pulmonary disease, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations