TreeWAS – Variant ID: rs4704397

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.987	0.013	0.000
E03 Other hypothyroidism	0.641	0.359	0.000
E03.8 Other specified hypothyroidism	0.533	0.467	0.000
E03.1 Congenital hypothyroidism without goitre	0.505	0.495	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.492	0.508	0.000
E03.5 Myxoedema coma	0.460	0.540	0.000
E03.4 Atrophy of thyroid (acquired)	0.460	0.540	0.000
E03.3 Postinfectious hypothyroidism	0.460	0.540	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.445	0.555	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.031	0.969	0.000
E00-E07 Disorders of thyroid gland	0.018	0.982	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.013	0.987	0.000
E00 Congenital iodine-deficiency syndrome	0.013	0.987	0.000
S52.6 Fracture of lower end of both ulna and radius	0.013	0.987	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.011	0.988	0.000
E07 Other disorders of thyroid	0.011	0.989	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
E06 Thyroiditis	0.010	0.990	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.009	0.990	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.009	0.990	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.009	0.990	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.009	0.990	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.009	0.990	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.009	0.990	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.009	0.990	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.009	0.990	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.991	0.009
D39.1 Ovary	0.009	0.991	0.000
I95.1 Orthostatic hypotension	0.000	0.992	0.008
E07.1 Dyshormogenetic goitre	0.008	0.992	0.000
E07.0 Hypersecretion of calcitonin	0.008	0.992	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.008	0.992	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.008	0.992	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.992	0.008
E27 Other disorders of adrenal gland	0.000	0.992	0.008
E07.8 Other specified disorders of thyroid	0.008	0.992	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.992	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.993	0.007
C18.2 Ascending colon	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.993	0.007
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.993	0.007
E06.4 Drug-induced thyroiditis	0.007	0.993	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.007	0.993	0.000
E06.0 Acute thyroiditis	0.007	0.993	0.000
E06.1 Subacute thyroiditis	0.007	0.993	0.000
E06.5 Other chronic thyroiditis	0.007	0.993	0.000
D75.1 Secondary polycythaemia	0.007	0.993	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.007	0.993	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.007	0.993	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.993	0.007
E07.9 Disorder of thyroid, unspecified	0.007	0.993	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.007	0.993	0.000
D47.1 Chronic myeloproliferative disease	0.007	0.993	0.000
T43.9 Psychotropic drug, unspecified	0.006	0.993	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.006	0.993	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.007	0.993	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.007	0.993	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.994	0.006
E06.9 Thyroiditis, unspecified	0.006	0.994	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.006
E27.0 Other adrenocortical overactivity	0.000	0.994	0.006
E06.3 Autoimmune thyroiditis	0.006	0.994	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
E27.2 Addisonian crisis	0.000	0.995	0.005
D37-D48 Neoplasms of uncertain or unknown behaviour	0.005	0.995	0.000
D45 Polycythaemia vera	0.005	0.995	0.000
F43.0 Acute stress reaction	0.005	0.995	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.005	0.995	0.000
D43.2 Brain, unspecified	0.005	0.995	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.005	0.995	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.005	0.995	0.000
I95.2 Hypotension due to drugs	0.000	0.995	0.005
K83.0 Cholangitis	0.005	0.995	0.000
D39.9 Female genital organ, unspecified	0.005	0.995	0.000
D39.2 Placenta	0.005	0.995	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.005	0.995	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.005	0.995	0.000
D39.0 Uterus	0.005	0.995	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.005	0.995	0.000
D39.7 Other female genital organs	0.005	0.995	0.000
S52.00 Fracture of upper end of ulna (closed)	0.005	0.995	0.000
D43.0 Brain, supratentorial	0.004	0.996	0.000
I95 Hypotension	0.000	0.996	0.004
D43.4 Spinal cord	0.004	0.996	0.000
D46 Myelodysplastic syndromes	0.004	0.996	0.000
D44.8 Pluriglandular involvement	0.004	0.996	0.000
M65.34 Trigger finger-Hand	0.004	0.996	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.004	0.996	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.004	0.996	0.000
D47.4 Osteomyelofibrosis	0.004	0.996	0.000
D43.9 Central nervous system, unspecified	0.004	0.996	0.000
D43.7 Other parts of central nervous system	0.004	0.996	0.000
D43.3 Cranial nerves	0.004	0.996	0.000
D44.1 Adrenal gland	0.004	0.996	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.004	0.996	0.000
C80 Malignant neoplasm without specification of site	0.000	0.996	0.004
D44.9 Endocrine gland, unspecified	0.004	0.996	0.000
E05.5 Thyroid crisis or storm	0.004	0.996	0.000
E05.4 Thyrotoxicosis factitia	0.004	0.996	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.004	0.996	0.000
D46.2 Refractory anaemia with excess of blasts	0.004	0.996	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.996	0.000
D44.6 Carotid body	0.004	0.996	0.000
E05.8 Other thyrotoxicosis	0.004	0.996	0.000
D44.5 Pineal gland	0.004	0.996	0.000
D44.2 Parathyroid gland	0.004	0.996	0.000
F43.2 Adjustment disorders	0.004	0.996	0.000
D47.2 Monoclonal gammopathy	0.004	0.996	0.000
D44.7 Aortic body and other paraganglia	0.003	0.996	0.000
D44.0 Thyroid gland	0.003	0.996	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.000	0.997	0.003
D46.5 Refractory anaemia with multi-lineage dysplasia	0.003	0.997	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.997	0.003
D44.4 Craniopharyngeal duct	0.003	0.997	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.003	0.997	0.000
D46.4 Refractory anaemia, unspecified	0.003	0.997	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.003	0.997	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.003	0.997	0.000
M65.3 Trigger finger	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
S52.0 Fracture of upper end of ulna	0.003	0.997	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.003	0.997	0.000
D43.1 Brain, infratentorial	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
M25.50 Pain in joint (Multiple sites)	0.003	0.997	0.000
D42.9 Meninges, unspecified	0.003	0.997	0.000
D46.7 Other myelodysplastic syndromes	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.003	0.997	0.000
D42.1 Spinal meninges	0.003	0.997	0.000
D42.0 Cerebral meninges	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
D44.3 Pituitary gland	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.003	0.997	0.000
S83.2 Tear of meniscus, current	0.003	0.997	0.000
D40.7 Other male genital organs	0.003	0.997	0.000
D46.1 Refractory anaemia with sideroblasts	0.003	0.997	0.000
C45 Mesothelioma	0.000	0.997	0.003
D75.2 Essential thrombocytosis	0.003	0.997	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
D38.0 Larynx	0.003	0.997	0.000
D40.9 Male genital organ, unspecified	0.003	0.997	0.000
C48.2 Peritoneum, unspecified	0.000	0.997	0.003
S52 Fracture of forearm	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
F43 Reaction to severe stress, and adjustment disorders	0.003	0.997	0.000
D40.0 Prostate	0.003	0.997	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.003	0.997	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
I95.0 Idiopathic hypotension	0.000	0.997	0.003
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
I95.8 Other hypotension	0.000	0.997	0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.997	0.003
M65.1 Other infective (teno)synovitis	0.003	0.997	0.000
M65 Synovitis and tenosynovitis	0.003	0.997	0.000
M65.39 Trigger finger-Site unspec	0.003	0.997	0.000
M65.38 Trigger finger-Other	0.003	0.997	0.000
M65.37 Trigger finger-Ankle/foot	0.003	0.997	0.000
M65.36 Trigger finger-Lower leg	0.003	0.997	0.000
M65.35 Trigger finger-Pelvic/thigh	0.003	0.997	0.000
M65.33 Trigger finger-Forearm	0.003	0.997	0.000
M65.32 Trigger finger-Upper arm	0.003	0.997	0.000
M65.31 Trigger finger-Shldr region	0.003	0.997	0.000
M65.30 Trigger finger-Mult sites	0.003	0.997	0.000
D38.6 Respiratory organ, unspecified	0.003	0.997	0.000
D38.4 Thymus	0.003	0.997	0.000
D38.2 Pleura	0.003	0.997	0.000
D38.3 Mediastinum	0.002	0.997	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.997	0.003
D48.5 Skin	0.003	0.997	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.003	0.997	0.000
D48.0 Bone and articular cartilage	0.003	0.997	0.000
J15.4 Pneumonia due to other streptococci	0.000	0.997	0.003
T79.8 Other early complications of trauma	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.002
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.002
D48.7 Other specified sites	0.003	0.997	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.003	0.997	0.000
Z57.3 Occupational exposure to other air contaminants	0.000	0.997	0.003
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.002
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.997	0.002
Z57.2 Occupational exposure to dust	0.000	0.997	0.002
T79.6 Traumatic ischaemia of muscle	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
S52.9 Fracture of forearm, part unspecified	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
D38.5 Other respiratory organs	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
F43.8 Other reactions to severe stress	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
M65.2 Calcific tendinitis	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.002	0.998	0.000
M65.18 Other infective (teno)synovitis (Other)	0.002	0.998	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.002	0.998	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.002	0.998	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.002	0.998	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.002	0.998	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.002	0.998	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
S52.3 Fracture of shaft of radius	0.002	0.998	0.000
S52.2 Fracture of shaft of ulna	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
F50.0 Anorexia nervosa	0.000	0.998	0.002
J93.9 Pneumothorax, unspecified	0.000	0.998	0.002
M65.0 Abscess of tendon sheath	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
B37.8 Candidiasis of other sites	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.998	0.002
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
M65.8 Other synovitis and tenosynovitis	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.998	0.002
C18.6 Descending colon	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
C48.0 Retroperitoneum	0.000	0.998	0.002
J93.1 Other spontaneous pneumothorax	0.000	0.998	0.002
K57.1 Diverticular disease of small intestine without perforation or abscess	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.002	0.998	0.000
S52.21 Fracture of shaft of ulna (open)	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.002	0.998	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.998	0.002
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.002	0.998	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.998	0.002
M65.84 Other synovitis and tenosynovitis (Hand)	0.002	0.998	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.998	0.002
C48.1 Specified parts of peritoneum	0.000	0.998	0.002
S52.91 Fracture of forearm, part unspecified (open)	0.002	0.998	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.002	0.998	0.000
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.002	0.998	0.000
M65.28 Calcific tendinitis (Other)	0.002	0.998	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.002	0.998	0.000
M65.26 Calcific tendinitis (Lower leg)	0.002	0.998	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.24 Calcific tendinitis (Hand)	0.002	0.998	0.000
M65.23 Calcific tendinitis (Forearm)	0.002	0.998	0.000
M65.22 Calcific tendinitis (Upper arm)	0.002	0.998	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.002	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
T79.9 Unspecified early complication of trauma	0.002	0.998	0.000
T79.5 Traumatic anuria	0.002	0.998	0.000
T79.4 Traumatic shock	0.002	0.998	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.002	0.998	0.000
T79.1 Fat embolism (traumatic)	0.002	0.998	0.000
T79.0 Air embolism (traumatic)	0.002	0.998	0.000
C17.2 Ileum	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.002	0.998	0.000
M65.08 Abscess of tendon sheath (Other)	0.002	0.998	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.002	0.998	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.002	0.998	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.002	0.998	0.000
M65.04 Abscess of tendon sheath (Hand)	0.002	0.998	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.002	0.998	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.002	0.998	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.002	0.998	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.002	0.998	0.000
S52.31 Fracture of shaft of radius (open)	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.998	0.002
Z57.7 Occupational exposure to vibration	0.000	0.998	0.002
Z57.6 Occupational exposure to extreme temperature	0.000	0.998	0.002
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.998	0.002
Z57.1 Occupational exposure to radiation	0.000	0.998	0.002
Z57.0 Occupational exposure to noise	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.002	0.998	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.002	0.998	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.002	0.998	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
S52.81 Fracture of other parts of forearm (open)	0.002	0.998	0.000
D16.4 Bones of skull and face	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.001	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.998	0.002
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C46 Kaposi's sarcoma	0.000	0.998	0.002
S52.71 Multiple fractures of forearm (open)	0.001	0.998	0.000
C17.1 Jejunum	0.002	0.998	0.000
F43.9 Reaction to severe stress, unspecified	0.001	0.998	0.000
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.002	0.998	0.000
S52.30 Fracture of shaft of radius (closed)	0.001	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
T38.7 Androgens and anabolic congeners	0.001	0.998	0.000
T38.5 Other oestrogens and progestogens	0.001	0.998	0.000
T38.4 Oral contraceptives	0.001	0.998	0.000
T38.2 Antithyroid drugs	0.001	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
E88.2 Lipomatosis, not elsewhere classified	0.002	0.998	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.000	0.998	0.002
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
Y60.0 During surgical operation	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.998	0.001
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
J93 Pneumothorax	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.001	0.998	0.000
C18.8 Overlapping lesion of colon	0.001	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.998	0.000
T50.5 Appetite depressants	0.001	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.998	0.000
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I98.0 Cardiovascular syphilis	0.000	0.998	0.001
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.998	0.000
T39.0 Salicylates	0.002	0.998	0.000
T47.4 Other laxatives	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.998	0.000
C17.9 Small intestine, unspecified	0.001	0.998	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.998	0.001
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.998	0.001
C46.7 Kaposi's sarcoma of other sites	0.000	0.998	0.001
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.998	0.001
C46.2 Kaposi's sarcoma of palate	0.000	0.998	0.001
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.998	0.001
C46.0 Kaposi's sarcoma of skin	0.000	0.998	0.001
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.998	0.001
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.998	0.001
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.998	0.001
C47.5 Peripheral nerves of pelvis	0.000	0.998	0.001
C47.4 Peripheral nerves of abdomen	0.000	0.998	0.001
C47.3 Peripheral nerves of thorax	0.000	0.998	0.001
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.998	0.001
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.998	0.001
C47.0 Peripheral nerves of head, face and neck	0.000	0.998	0.001
F50.2 Bulimia nervosa	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations