TreeWAS – Variant ID: rs4711751

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G80 Infantile cerebral palsy	0.141	0.859	0.000
G80.9 Infantile cerebral palsy, unspecified	0.141	0.859	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.132	0.868	0.000
G81 Hemiplegia	0.127	0.873	0.000
G80.1 Spastic diplegia	0.125	0.875	0.000
G81.9 Hemiplegia, unspecified	0.120	0.880	0.000
G80.8 Other infantile cerebral palsy	0.114	0.886	0.000
G82 Paraplegia and tetraplegia	0.114	0.886	0.000
G80.0 Spastic cerebral palsy	0.113	0.887	0.000
G80.2 Infantile hemiplegia	0.109	0.891	0.000
G83 Other paralytic syndromes	0.106	0.894	0.000
G82.1 Spastic paraplegia	0.106	0.894	0.000
G81.1 Spastic hemiplegia	0.105	0.895	0.000
G80.4 Ataxic cerebral palsy	0.102	0.898	0.000
G80.3 Dyskinetic cerebral palsy	0.102	0.898	0.000
G82.2 Paraplegia, unspecified	0.099	0.901	0.000
G83.2 Monoplegia of upper limb	0.093	0.907	0.000
G81.0 Flaccid hemiplegia	0.091	0.909	0.000
G83.9 Paralytic syndrome, unspecified	0.086	0.914	0.000
G83.1 Monoplegia of lower limb	0.082	0.918	0.000
G82.3 Flaccid tetraplegia	0.082	0.918	0.000
G82.0 Flaccid paraplegia	0.082	0.918	0.000
G83.5 Locked-in syndrome	0.076	0.924	0.000
G83.3 Monoplegia, unspecified	0.076	0.924	0.000
G83.0 Diplegia of upper limbs	0.076	0.924	0.000
G83.8 Other specified paralytic syndromes	0.066	0.934	0.000
G82.5 Tetraplegia, unspecified	0.065	0.935	0.000
G83.4 Cauda equina syndrome	0.050	0.950	0.000
G82.4 Spastic tetraplegia	0.048	0.951	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.020	0.980	0.000
H72.0 Central perforation of tympanic membrane	0.017	0.983	0.000
H72 Perforation of tympanic membrane	0.017	0.983	0.000
N90.5 Atrophy of vulva	0.000	0.984	0.016
J33.9 Nasal polyp, unspecified	0.016	0.984	0.000
H72.8 Other perforations of tympanic membrane	0.015	0.985	0.000
H72.1 Attic perforation of tympanic membrane	0.014	0.986	0.000
H72.2 Other marginal perforations of tympanic membrane	0.013	0.987	0.000
E10.9 Without complications	0.000	0.987	0.013
E03.9 Hypothyroidism, unspecified	0.012	0.988	0.000
H65 Nonsuppurative otitis media	0.012	0.988	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.988	0.012
H65-H75 Diseases of middle ear and mastoid	0.012	0.988	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.000	0.988	0.012
H72.9 Perforation of tympanic membrane, unspecified	0.012	0.988	0.000
N90.6 Hypertrophy of vulva	0.000	0.989	0.011
E10.4 With neurological complications	0.000	0.989	0.011
E10 Insulin-dependent diabetes mellitus	0.000	0.989	0.011
H74 Other disorders of middle ear and mastoid	0.011	0.989	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.010	0.990	0.000
E10.6 With other specified complications	0.000	0.990	0.010
N90.4 Leukoplakia of vulva	0.000	0.990	0.010
H71 Cholesteatoma of middle ear	0.009	0.991	0.000
H65.1 Other acute nonsuppurative otitis media	0.009	0.991	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.991	0.009
E03 Other hypothyroidism	0.009	0.991	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.009	0.991	0.000
E10.5 With peripheral circulatory complications	0.000	0.991	0.009
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.991	0.000
H67 Otitis media in diseases classified elsewhere	0.009	0.991	0.000
N90.3 Dysplasia of vulva, unspecified	0.000	0.991	0.009
H70 Mastoiditis and related conditions	0.009	0.991	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.000	0.991	0.009
E10.7 With multiple complications	0.000	0.991	0.009
H65.4 Other chronic nonsuppurative otitis media	0.009	0.991	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.991	0.009
H74.4 Polyp of middle ear	0.008	0.992	0.000
H74.1 Adhesive middle ear disease	0.008	0.992	0.000
H68 Eustachian salpingitis and obstruction	0.008	0.992	0.000
N90.0 Mild vulvar dysplasia	0.000	0.992	0.008
E03.8 Other specified hypothyroidism	0.008	0.992	0.000
S02.8 Fractures of other skull and facial bones	0.008	0.992	0.000
E10.0 With coma	0.000	0.992	0.008
H74.9 Disorder of middle ear and mastoid, unspecified	0.008	0.992	0.000
H69 Other disorders of Eustachian tube	0.008	0.992	0.000
H74.0 Tympanosclerosis	0.008	0.992	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.008	0.992	0.000
H70.0 Acute mastoiditis	0.008	0.992	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.008	0.992	0.000
N90.1 Moderate vulvar dysplasia	0.000	0.992	0.007
E10.8 With unspecified complications	0.000	0.992	0.007
H74.8 Other specified disorders of middle ear and mastoid	0.007	0.993	0.000
K52.3 Indeterminate colitis	0.007	0.993	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.007	0.993	0.000
H66 Suppurative and unspecified otitis media	0.007	0.993	0.000
H70.8 Other mastoiditis and related conditions	0.007	0.993	0.000
E03.1 Congenital hypothyroidism without goitre	0.007	0.993	0.000
E03.5 Myxoedema coma	0.007	0.993	0.000
E03.4 Atrophy of thyroid (acquired)	0.007	0.993	0.000
E03.3 Postinfectious hypothyroidism	0.007	0.993	0.000
H65.0 Acute serous otitis media	0.007	0.993	0.000
E10.1 With ketoacidosis	0.000	0.993	0.007
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.007	0.993	0.000
H65.3 Chronic mucoid otitis media	0.007	0.993	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.006	0.993	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.006	0.993	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.006	0.993	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.993	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
H70.2 Petrositis	0.006	0.993	0.000
E10.2 With renal complications	0.000	0.993	0.006
S02.20 Fracture of nasal bones (closed)	0.006	0.994	0.000
H68.0 Eustachian salpingitis	0.006	0.994	0.000
S02 Fracture of skull and facial bones	0.006	0.994	0.000
H65.2 Chronic serous otitis media	0.006	0.994	0.000
H70.1 Chronic mastoiditis	0.006	0.994	0.000
S02.2 Fracture of nasal bones	0.006	0.994	0.000
S02.81 Fractures of other skull and facial bones (open)	0.006	0.994	0.000
H73 Other disorders of tympanic membrane	0.006	0.994	0.000
H69.0 Patulous Eustachian tube	0.006	0.994	0.000
H69.8 Other specified disorders of Eustachian tube	0.006	0.994	0.000
S02.3 Fracture of orbital floor	0.006	0.994	0.000
Y42.7 Androgens and anabolic congeners	0.006	0.994	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.006	0.994	0.000
H68.1 Obstruction of Eustachian tube	0.005	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.005	0.994	0.000
I71 Aortic aneurysm and dissection	0.006	0.994	0.000
S02.30 Fracture of orbital floor (closed)	0.005	0.994	0.000
H66.3 Other chronic suppurative otitis media	0.005	0.995	0.000
H66.0 Acute suppurative otitis media	0.005	0.995	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.005	0.995	0.000
S02.1 Fracture of base of skull	0.005	0.995	0.000
H16.0 Corneal ulcer	0.005	0.995	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.995	0.000
E10.3 With ophthalmic complications	0.000	0.995	0.005
S02.5 Fracture of tooth	0.005	0.995	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.995	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.005	0.995	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.995	0.005
S02.0 Fracture of vault of skull	0.005	0.995	0.000
S02.10 Fracture of base of skull (closed)	0.005	0.995	0.000
H69.9 Eustachian tube disorder, unspecified	0.005	0.995	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
H70.9 Mastoiditis, unspecified	0.004	0.995	0.000
S02.7 Multiple fractures involving skull and facial bones	0.005	0.995	0.000
D25.9 Leiomyoma of uterus, unspecified	0.000	0.995	0.005
Y42.1 Thyroid hormones and substitutes	0.005	0.995	0.000
Y45.1 Salicylates	0.005	0.995	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.005	0.995	0.000
H16 Keratitis	0.004	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.004	0.996	0.000
Y45.2 Propionic acid derivatives	0.004	0.996	0.000
S02.31 Fracture of orbital floor (open)	0.004	0.996	0.000
H73.0 Acute myringitis	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.004	0.996	0.000
H73.1 Chronic myringitis	0.004	0.996	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.004	0.996	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.004	0.996	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.004	0.996	0.000
S02.50 Fracture of tooth (closed)	0.004	0.996	0.000
S02.6 Fracture of mandible	0.004	0.996	0.000
S02.01 Fracture of vault of skull (open)	0.004	0.996	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.004	0.996	0.000
S02.21 Fracture of nasal bones (open)	0.004	0.996	0.000
H16.2 Keratoconjunctivitis	0.004	0.996	0.000
H16.8 Other keratitis	0.004	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
Y42.2 Antithyroid drugs	0.004	0.996	0.000
S02.51 Fracture of tooth (open)	0.004	0.996	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.004	0.996	0.000
N71.1 Chronic inflammatory disease of uterus	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
J33 Nasal polyp	0.004	0.996	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.996	0.004
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.004	0.996	0.000
Y42.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
Y42.4 Oral contraceptives	0.004	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.004	0.996	0.000
S02.11 Fracture of base of skull (open)	0.003	0.996	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.003	0.996	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.003	0.996	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.003	0.996	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
J33.1 Polypoid sinus degeneration	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.003	0.997	0.000
K26.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
R73 Elevated blood glucose level	0.000	0.997	0.003
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
H16.4 Corneal neovascularisation	0.003	0.997	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.000	0.997	0.003
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
Y41.4 Anthelminthics	0.003	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.003	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
I71.0 Dissection of aorta [any part]	0.003	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.003	0.997	0.000
Y53.2 Stimulant laxatives	0.003	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.003
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.003	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
Y53.7 Emetics	0.003	0.997	0.000
Y53.5 Digestants	0.003	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.003	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y53.4 Other laxatives	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
J33.8 Other polyp of sinus	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
S02.60 Fracture of mandible (closed)	0.003	0.997	0.000
Y41.0 Sulphonamides	0.002	0.997	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.003	0.997	0.000
S51.0 Open wound of elbow	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.997	0.000
Y46.8 Antispasticity drugs	0.002	0.997	0.000
Y46.3 Deoxybarbiturates	0.002	0.997	0.000
Y46.1 Oxazolidinediones	0.002	0.997	0.000
Y46.0 Succinimides	0.002	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
H20 Iridocyclitis	0.003	0.997	0.000
N71 Inflammatory disease of uterus, except cervix	0.003	0.997	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.997	0.003
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
Y50.9 Central nervous system stimulant, unspecified	0.002	0.997	0.000
Y50.8 Other central nervous system stimulants	0.002	0.997	0.000
Y50.1 Opioid receptor antagonists	0.002	0.997	0.000
Y50.0 Analeptics	0.002	0.997	0.000
Y59.3 Immunoglobulin	0.002	0.997	0.000
Y44.5 Thrombolytic drugs	0.002	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.002
Y54.9 Mineral salts, not elsewhere classified	0.002	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.997	0.000
Y54.0 Mineralocorticoids	0.002	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.998	0.002
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
G71.1 Myotonic disorders	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
S50.0 Contusion of elbow	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
C16.0 Cardia	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
N71.0 Acute inflammatory disease of uterus	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
M11.2 Other chondrocalcinosis	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.002	0.998	0.000
C16.2 Body of stomach	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
Z59.0 Homelessness	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
E87.7 Fluid overload	0.000	0.998	0.002
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.998	0.002
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
C16.1 Fundus of stomach	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.002	0.998	0.000
G71.8 Other primary disorders of muscles	0.002	0.998	0.000
G71.2 Congenital myopathies	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
G70 Myasthenia gravis and other myoneural disorders	0.002	0.998	0.000
C16.8 Overlapping lesion of stomach	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
C16.4 Pylorus	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
Y84.6 Urinary catheterisation	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
K60.1 Chronic anal fissure	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.002	0.998	0.000
D04.5 Skin of trunk	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.998	0.002
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.998	0.002
Y40.4 Tetracyclines	0.002	0.998	0.000
G70-G73 Diseases of myoneural junction and muscle	0.002	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.001
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.998	0.002
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.001
A46 Erysipelas	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.001	0.998	0.000
G70.2 Congenital and developmental myasthenia	0.001	0.998	0.000
G70.1 Toxic myoneural disorders	0.001	0.998	0.000
X63.0 Home	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.001	0.998	0.000
C16.3 Pyloric antrum	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
S51.7 Multiple open wounds of forearm	0.002	0.998	0.000
V02.1 Traffic accident	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.001	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.998	0.002
S50 Superficial injury of forearm	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.000	0.998	0.002
Y40.3 Macrolides	0.001	0.998	0.000
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
J31.2 Chronic pharyngitis	0.002	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.998	0.002
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.001	0.998	0.000
C69.6 Orbit	0.001	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.001	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.001
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.001	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.001	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations