TreeWAS – Variant ID: rs4713099

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.382	0.618
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.461	0.539
K90.9 Intestinal malabsorption, unspecified	0.000	0.497	0.503
K90.3 Pancreatic steatorrhoea	0.000	0.557	0.443
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.557	0.443
K90.1 Tropical sprue	0.000	0.557	0.443
K90.8 Other intestinal malabsorption	0.000	0.662	0.337
E03.9 Hypothyroidism, unspecified	0.000	0.729	0.271
E83 Disorders of mineral metabolism	0.184	0.816	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.144	0.855	0.000
E83.8 Other disorders of mineral metabolism	0.132	0.868	0.000
E83.2 Disorders of zinc metabolism	0.132	0.868	0.000
E83.0 Disorders of copper metabolism	0.132	0.868	0.000
E83.3 Disorders of phosphorus metabolism	0.124	0.876	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.104	0.896	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.102	0.898	0.000
T39.1 4-Aminophenol derivatives	0.101	0.899	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.101	0.899	0.000
E88 Other metabolic disorders	0.099	0.901	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.096	0.904	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.094	0.906	0.000
E70-E90 Metabolic disorders	0.093	0.907	0.000
T42.4 Benzodiazepines	0.093	0.907	0.000
E03 Other hypothyroidism	0.000	0.908	0.092
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.090	0.909	0.000
T40.2 Other opioids	0.090	0.910	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.089	0.911	0.000
E85 Amyloidosis	0.088	0.911	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.085	0.915	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.084	0.916	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.084	0.916	0.000
E88.3 Tumour lysis syndrome	0.083	0.917	0.000
T42.0 Hydantoin derivatives	0.082	0.918	0.000
E85.9 Amyloidosis, unspecified	0.082	0.918	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.082	0.918	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.079	0.921	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.079	0.921	0.000
T50.8 Diagnostic agents	0.077	0.923	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.076	0.924	0.000
E85.8 Other amyloidosis	0.076	0.924	0.000
T39.0 Salicylates	0.076	0.924	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.075	0.925	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.074	0.926	0.000
T50.1 Loop [high-ceiling] diuretics	0.074	0.926	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.074	0.926	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.074	0.926	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.074	0.926	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.073	0.927	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.073	0.927	0.000
T39.4 Antirheumatics, not elsewhere classified	0.072	0.927	0.000
T39.2 Pyrazolone derivatives	0.072	0.927	0.000
T50.4 Drugs affecting uric acid metabolism	0.073	0.927	0.000
E83.4 Disorders of magnesium metabolism	0.072	0.928	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.071	0.929	0.000
E72 Other disorders of amino-acid metabolism	0.071	0.929	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.069	0.931	0.000
T42.3 Barbiturates	0.069	0.931	0.000
T42.2 Succinimides and oxazolidinediones	0.069	0.931	0.000
E85.3 Secondary systemic amyloidosis	0.069	0.931	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.068	0.931	0.000
T50.7 Analeptics and opioid receptor antagonists	0.068	0.932	0.000
T50.5 Appetite depressants	0.068	0.932	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.068	0.932	0.000
T50.0 Mineralocorticoids and their antagonists	0.068	0.932	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.068	0.932	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.068	0.932	0.000
T36 Poisoning by systemic antibiotics	0.068	0.932	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.068	0.932	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.933	0.067
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.067	0.933	0.000
E77 Disorders of glycoprotein metabolism	0.067	0.933	0.000
E76 Disorders of glycosaminoglycan metabolism	0.067	0.933	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.067	0.933	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.067	0.933	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.067	0.933	0.000
E88.2 Lipomatosis, not elsewhere classified	0.067	0.933	0.000
T40.1 Heroin	0.066	0.934	0.000
E70 Disorders of aromatic amino-acid metabolism	0.066	0.934	0.000
E03.5 Myxoedema coma	0.000	0.934	0.066
E03.4 Atrophy of thyroid (acquired)	0.000	0.934	0.066
E03.3 Postinfectious hypothyroidism	0.000	0.934	0.066
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.934	0.065
E80.1 Porphyria cutanea tarda	0.065	0.935	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.065	0.935	0.000
T40.8 Lysergide [LSD]	0.065	0.935	0.000
T40.7 Cannabis (derivatives)	0.065	0.935	0.000
T40.3 Methadone	0.065	0.935	0.000
T40.0 Opium	0.065	0.935	0.000
E88.8 Other specified metabolic disorders	0.065	0.935	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.065	0.935	0.000
E84 Cystic fibrosis	0.065	0.935	0.000
T43.9 Psychotropic drug, unspecified	0.065	0.935	0.000
T40.5 Cocaine	0.064	0.936	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.064	0.936	0.000
T48.5 Anti-common-cold drugs	0.064	0.936	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.064	0.936	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.064	0.936	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.064	0.936	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.063	0.937	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.063	0.937	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.063	0.937	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.938	0.062
T42.1 Iminostilbenes	0.061	0.938	0.000
E88.9 Metabolic disorder, unspecified	0.061	0.939	0.000
T45.2 Vitamins, not elsewhere classified	0.061	0.939	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.061	0.939	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.061	0.939	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.060	0.939	0.000
T37.5 Antiviral drugs	0.060	0.939	0.000
T37.4 Anthelminthics	0.060	0.939	0.000
T37.3 Other antiprotozoal drugs	0.060	0.939	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.060	0.939	0.000
T37.1 Antimycobacterial drugs	0.060	0.939	0.000
T37.0 Sulphonamides	0.060	0.939	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.060	0.939	0.000
T48.4 Expectorants	0.060	0.939	0.000
T48.3 Antitussives	0.060	0.939	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.060	0.939	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.060	0.939	0.000
T48.0 Oxytocic drugs	0.060	0.939	0.000
E79 Disorders of purine and pyrimidine metabolism	0.060	0.940	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.060	0.940	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.058	0.942	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.058	0.942	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.058	0.942	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.057	0.943	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.057	0.943	0.000
T38.9 Other and unspecified hormone antagonists	0.057	0.943	0.000
T38.7 Androgens and anabolic congeners	0.057	0.943	0.000
T38.5 Other oestrogens and progestogens	0.057	0.943	0.000
T38.4 Oral contraceptives	0.057	0.943	0.000
T38.2 Antithyroid drugs	0.057	0.943	0.000
T38.0 Glucocorticoids and synthetic analogues	0.057	0.943	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.057	0.943	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.944	0.056
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.055	0.944	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.055	0.945	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.054	0.946	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.054	0.946	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.054	0.946	0.000
T46.7 Peripheral vasodilators	0.054	0.946	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.054	0.946	0.000
E85.4 Organ-limited amyloidosis	0.054	0.946	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.053	0.946	0.000
T40.6 Other and unspecified narcotics	0.053	0.946	0.000
E80.6 Other disorders of bilirubin metabolism	0.053	0.947	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.053	0.947	0.000
T45.8 Other primarily systemic and haematological agents	0.053	0.947	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.053	0.947	0.000
T45.6 Fibrinolysis-affecting drugs	0.053	0.947	0.000
T45.4 Iron and its compounds	0.053	0.947	0.000
T45.3 Enzymes, not elsewhere classified	0.053	0.947	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.053	0.947	0.000
E80.5 Crigler-Najjar syndrome	0.053	0.947	0.000
E80.3 Defects of catalase and peroxydase	0.053	0.947	0.000
E80.0 Hereditary erythropoietic porphyria	0.053	0.947	0.000
T41.5 Therapeutic gases	0.053	0.947	0.000
T41.4 Anaesthetic, unspecified	0.053	0.947	0.000
T41.3 Local anaesthetics	0.053	0.947	0.000
T41.2 Other and unspecified general anaesthetics	0.053	0.947	0.000
T41.1 Intravenous anaesthetics	0.053	0.947	0.000
T41.0 Inhaled anaesthetics	0.053	0.947	0.000
T38.1 Thyroid hormones and substitutes	0.053	0.947	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.053	0.947	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.053	0.947	0.000
T47.7 Emetics	0.053	0.947	0.000
T47.6 Antidiarrhoeal drugs	0.053	0.947	0.000
T47.5 Digestants	0.053	0.947	0.000
T47.4 Other laxatives	0.053	0.947	0.000
T47.3 Saline and osmotic laxatives	0.053	0.947	0.000
T49.9 Topical agent, unspecified	0.052	0.948	0.000
T49.8 Other topical agents	0.052	0.948	0.000
T49.7 Dental drugs, topically applied	0.052	0.948	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.052	0.948	0.000
T49.5 Ophthalmological drugs and preparations	0.052	0.948	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.052	0.948	0.000
T49.3 Emollients, demulcents and protectants	0.052	0.948	0.000
T49.2 Local astringents and local detergents	0.052	0.948	0.000
T49.1 Antipruritics	0.052	0.948	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.052	0.948	0.000
E89.4 Postprocedural ovarian failure	0.052	0.948	0.000
E74 Other disorders of carbohydrate metabolism	0.052	0.948	0.000
E73 Lactose intolerance	0.052	0.948	0.000
T47.2 Stimulant laxatives	0.051	0.948	0.000
E75.2 Other sphingolipidosis	0.051	0.949	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.051	0.949	0.000
T36.4 Tetracyclines	0.051	0.949	0.000
T43.2 Other and unspecified antidepressants	0.051	0.949	0.000
E80.2 Other porphyria	0.051	0.949	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.051	0.949	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.051	0.949	0.000
E72.5 Disorders of glycine metabolism	0.051	0.949	0.000
E72.4 Disorders of ornithine metabolism	0.051	0.949	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.051	0.949	0.000
E72.2 Disorders of urea cycle metabolism	0.051	0.949	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.050	0.950	0.000
E72.0 Disorders of amino-acid transport	0.050	0.950	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.050	0.950	0.000
T36.3 Macrolides	0.050	0.950	0.000
T43.6 Psychostimulants with abuse potential	0.049	0.950	0.000
E75.6 Lipid storage disorder, unspecified	0.049	0.951	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.049	0.951	0.000
E75.3 Sphingolipidosis, unspecified	0.049	0.951	0.000
E75.1 Other gangliosidosis	0.049	0.951	0.000
E75.0 GM2 gangliosidosis	0.049	0.951	0.000
T36.9 Systemic antibiotic, unspecified	0.049	0.951	0.000
T36.8 Other systemic antibiotics	0.049	0.951	0.000
T36.7 Antifungal antibiotics, systemically used	0.049	0.951	0.000
T36.6 Rifamycins	0.049	0.951	0.000
T36.5 Aminoglycosides	0.049	0.951	0.000
T36.2 Chloramphenicol group	0.049	0.951	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.049	0.951	0.000
E71.3 Disorders of fatty-acid metabolism	0.048	0.952	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.048	0.952	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.048	0.952	0.000
E71.0 Maple-syrup-urine disease	0.048	0.952	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.048	0.952	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.048	0.952	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.048	0.952	0.000
E76.2 Other mucopolysaccharidoses	0.048	0.952	0.000
E76.1 Mucopolysaccharidosis, type II	0.048	0.952	0.000
E76.0 Mucopolysaccharidosis, type I	0.048	0.952	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.048	0.952	0.000
E77.8 Other disorders of glycoprotein metabolism	0.048	0.952	0.000
E77.1 Defects in glycoprotein degradation	0.048	0.952	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.048	0.952	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.047	0.952	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.047	0.952	0.000
E70.2 Disorders of tyrosine metabolism	0.047	0.952	0.000
E70.1 Other hyperphenylalaninaemias	0.047	0.952	0.000
E70.0 Classical phenylketonuria	0.047	0.952	0.000
T45.5 Anticoagulants	0.048	0.952	0.000
T47.0 Histamine H(2)-receptor antagonists	0.047	0.952	0.000
E70.3 Albinism	0.047	0.953	0.000
E84.8 Cystic fibrosis with other manifestations	0.047	0.953	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.047	0.953	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.047	0.953	0.000
E75.5 Other lipid storage disorders	0.046	0.954	0.000
E89.1 Postprocedural hypoinsulinaemia	0.046	0.954	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.955	0.045
E80.4 Gilbert's syndrome	0.045	0.955	0.000
E84.9 Cystic fibrosis, unspecified	0.044	0.956	0.000
E00-E07 Disorders of thyroid gland	0.000	0.956	0.044
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.043	0.957	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.043	0.957	0.000
E79.1 Lesch-Nyhan syndrome	0.043	0.957	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.043	0.957	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.043	0.957	0.000
E89.5 Postprocedural testicular hypofunction	0.043	0.957	0.000
T45.0 Antiallergic and antiemetic drugs	0.043	0.957	0.000
K90-K93 Other diseases of the digestive system	0.000	0.958	0.042
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.041	0.959	0.000
E03.8 Other specified hypothyroidism	0.000	0.960	0.040
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.039	0.961	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.039	0.961	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.039	0.961	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.039	0.961	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.039	0.961	0.000
T44.0 Anticholinesterase agents	0.039	0.961	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.037	0.963	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.037	0.963	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.037	0.963	0.000
E74.2 Disorders of galactose metabolism	0.037	0.963	0.000
E74.1 Disorders of fructose metabolism	0.037	0.963	0.000
E74.0 Glycogen storage disease	0.037	0.963	0.000
E73.8 Other lactose intolerance	0.037	0.963	0.000
E73.1 Secondary lactase deficiency	0.037	0.963	0.000
E73.0 Congenital lactase deficiency	0.037	0.963	0.000
T36.0 Penicillins	0.037	0.963	0.000
T46.1 Calcium-channel blockers	0.037	0.963	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.037	0.963	0.000
E89.0 Postprocedural hypothyroidism	0.037	0.963	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.036	0.964	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.035	0.965	0.000
K40 Inguinal hernia	0.034	0.966	0.000
E05.5 Thyroid crisis or storm	0.000	0.967	0.033
E05.4 Thyrotoxicosis factitia	0.000	0.967	0.033
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.967	0.033
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.967	0.033
M25.57 Pain in joint (Ankle and foot)	0.032	0.968	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.968	0.032
E00 Congenital iodine-deficiency syndrome	0.000	0.968	0.032
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.969	0.030
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.970	0.030
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.029	0.971	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.028	0.972	0.000
E89.3 Postprocedural hypopituitarism	0.027	0.973	0.000
T40.4 Other synthetic narcotics	0.026	0.974	0.001
E05.8 Other thyrotoxicosis	0.000	0.974	0.026
E07 Other disorders of thyroid	0.000	0.974	0.026
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.025	0.975	0.000
M20.1 Hallux valgus (acquired)	0.025	0.975	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.975	0.025
K40.1 Bilateral inguinal hernia, with gangrene	0.025	0.975	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.025	0.975	0.000
E89.2 Postprocedural hypoparathyroidism	0.024	0.975	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.976	0.024
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.024	0.976	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.977	0.023
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.977	0.023
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.977	0.023
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.977	0.023
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.977	0.023
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.977	0.023
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.977	0.023
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.977	0.023
E74.3 Other disorders of intestinal carbohydrate absorption	0.022	0.978	0.001
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.978	0.022
K93.1 Megacolon in Chagas' disease	0.000	0.978	0.022
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.978	0.022
E73.9 Lactose intolerance, unspecified	0.022	0.978	0.000
E07.8 Other specified disorders of thyroid	0.000	0.980	0.020
E06 Thyroiditis	0.000	0.981	0.019
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.981	0.019
E07.1 Dyshormogenetic goitre	0.000	0.981	0.018
E07.0 Hypersecretion of calcitonin	0.000	0.981	0.018
M20 Acquired deformities of fingers and toes	0.017	0.983	0.000
M20.4 Other hammer toe(s) (acquired)	0.017	0.983	0.000
I46 Cardiac arrest	0.000	0.983	0.017
M20.6 Acquired deformity of toe(s), unspecified	0.016	0.984	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.016	0.984	0.000
M20.5 Other deformities of toe(s) (acquired)	0.016	0.984	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.984	0.016
G24.9 Dystonia, unspecified	0.016	0.984	0.000
G24 Dystonia	0.016	0.984	0.000
G24.3 Spasmodic torticollis	0.015	0.985	0.000
E06.9 Thyroiditis, unspecified	0.000	0.986	0.014
E06.4 Drug-induced thyroiditis	0.000	0.986	0.014
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.986	0.014
E06.0 Acute thyroiditis	0.000	0.986	0.014
G95.8 Other specified diseases of spinal cord	0.014	0.986	0.000
G24.8 Other dystonia	0.013	0.987	0.000
E06.5 Other chronic thyroiditis	0.000	0.987	0.012
I46.1 Sudden cardiac death, so described	0.000	0.988	0.012
E06.1 Subacute thyroiditis	0.000	0.988	0.012
G24.5 Blepharospasm	0.012	0.988	0.000
G95 Other diseases of spinal cord	0.012	0.988	0.000
G95.9 Disease of spinal cord, unspecified	0.012	0.988	0.000
G24.1 Idiopathic familial dystonia	0.012	0.988	0.000
G30.9 Alzheimer's disease, unspecified	0.012	0.988	0.000
G24.4 Idiopathic orofacial dystonia	0.011	0.989	0.000
G24.2 Idiopathic nonfamilial dystonia	0.011	0.989	0.000
G24.0 Drug-induced dystonia	0.011	0.989	0.000
G30 Alzheimer's disease	0.011	0.989	0.000
M20.0 Deformity of finger(s)	0.011	0.989	0.000
G95.0 Syringomyelia and syringobulbia	0.011	0.989	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.011	0.989	0.000
G30.0 Alzheimer's disease with early onset	0.010	0.990	0.000
N02.9 Unspecified	0.010	0.990	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.990	0.010
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.010	0.990	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.010	0.990	0.000
G95.1 Vascular myelopathies	0.010	0.990	0.000
G20-G26 Extrapyramidal and movement disorders	0.010	0.990	0.000
G30-G32 Other degenerative diseases of the nervous system	0.009	0.991	0.000
G25 Other extrapyramidal and movement disorders	0.009	0.991	0.000
G31.8 Other specified degenerative diseases of nervous system	0.009	0.991	0.000
E06.3 Autoimmune thyroiditis	0.000	0.991	0.009
G30.8 Other Alzheimer's disease	0.009	0.991	0.000
G30.1 Alzheimer's disease with late onset	0.008	0.991	0.000
R27.0 Ataxia, unspecified	0.009	0.991	0.000
J06.9 Acute upper respiratory infection, unspecified	0.008	0.992	0.000
G25.1 Drug-induced tremor	0.008	0.992	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.992	0.008
G21 Secondary Parkinsonism	0.008	0.992	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.008	0.992	0.000
H11.0 Pterygium	0.000	0.993	0.007
G25.5 Other chorea	0.007	0.993	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.993	0.007
H11 Other disorders of conjunctiva	0.000	0.993	0.007
G31.1 Senile degeneration of brain, not elsewhere classified	0.007	0.993	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.993	0.007
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.007	0.993	0.000
G22 Parkinsonism in diseases classified elsewhere	0.007	0.993	0.000
G25.2 Other specified forms of tremor	0.007	0.993	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.007	0.993	0.000
G25.4 Drug-induced chorea	0.007	0.993	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.007	0.993	0.000
R27.8 Other and unspecified lack of coordination	0.007	0.993	0.000
G23 Other degenerative diseases of basal ganglia	0.007	0.993	0.000
D73.0 Hyposplenism	0.007	0.993	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.993	0.007
M25.5 Pain in joint	0.007	0.993	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.007	0.993	0.000
R27 Other lack of coordination	0.007	0.993	0.000
D73.8 Other diseases of spleen	0.007	0.993	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.007	0.993	0.000
M25.52 Pain in joint (Upper arm)	0.006	0.993	0.000
E83.5 Disorders of calcium metabolism	0.006	0.994	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.994	0.006
G21.1 Other drug-induced secondary Parkinsonism	0.006	0.994	0.000
M20.3 Other deformity of hallux (acquired)	0.006	0.994	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.994	0.006
D73 Diseases of spleen	0.006	0.994	0.000
G25.3 Myoclonus	0.006	0.994	0.000
G31.0 Circumscribed brain atrophy	0.006	0.994	0.000
G21.4 Vascular parkinsonism	0.006	0.994	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.006	0.994	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.994	0.006
G21.9 Secondary Parkinsonism, unspecified	0.006	0.994	0.000
G21.8 Other secondary Parkinsonism	0.006	0.994	0.000
G21.3 Postencephalitic Parkinsonism	0.006	0.994	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.006	0.994	0.000
G21.0 Malignant neuroleptic syndrome	0.006	0.994	0.000
E86 Volume depletion	0.006	0.994	0.000
G63.2 Diabetic polyneuropathy	0.006	0.994	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.994	0.006
H11.2 Conjunctival scars	0.000	0.995	0.005
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.005	0.995	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.005	0.995	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.005	0.995	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.995	0.005
Q25.1 Coarctation of aorta	0.005	0.995	0.000
G25.0 Essential tremor	0.005	0.995	0.000
D73.3 Abscess of spleen	0.005	0.995	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.005	0.995	0.000
G23.3 Multiple system atrophy, cerebellar type	0.005	0.995	0.000
G23.2 Striatonigral degeneration	0.005	0.995	0.000
G23.0 Hallervorden-Spatz disease	0.005	0.995	0.000
K91.1 Postgastric surgery syndromes	0.000	0.995	0.005
G23.8 Other specified degenerative diseases of basal ganglia	0.005	0.995	0.000
M25.50 Pain in joint (Multiple sites)	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
M25.53 Pain in joint (Forearm)	0.005	0.995	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.005	0.995	0.000
Q25.4 Other congenital malformations of aorta	0.005	0.995	0.000
G95.2 Cord compression, unspecified	0.005	0.995	0.000
N02 Recurrent and persistent haematuria	0.005	0.995	0.000
S01.9 Open wound of head, part unspecified	0.005	0.995	0.000
M25.58 Pain in joint (Other)	0.004	0.995	0.000
D73.2 Chronic congestive splenomegaly	0.004	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.004	0.996	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.996	0.004
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.996	0.004
D73.4 Cyst of spleen	0.004	0.996	0.000
S62.50 Fracture of thumb (closed)	0.000	0.996	0.004
M25.59 Pain in joint (Site unspecified)	0.004	0.996	0.000
D73.5 Infarction of spleen	0.004	0.996	0.000
F41.9 Anxiety disorder, unspecified	0.004	0.996	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.996	0.004
D73.1 Hypersplenism	0.004	0.996	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.996	0.004
J06 Acute upper respiratory infections of multiple and unspecified sites	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
K76.8 Other specified diseases of liver	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
M25.54 Pain in joint (Hand)	0.004	0.996	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.996	0.004
C71.2 Temporal lobe	0.000	0.996	0.004
K07.3 Anomalies of tooth position	0.000	0.996	0.004
N02.8 Other	0.004	0.996	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.003	0.996	0.000
N02.6 Dense deposit disease	0.003	0.996	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.996	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.996	0.000
N02.1 Focal and segmental glomerular lesions	0.003	0.996	0.000
N02.0 Minor glomerular abnormality	0.003	0.996	0.000
H11.3 Conjunctival haemorrhage	0.000	0.996	0.004
G63 Polyneuropathy in diseases classified elsewhere	0.003	0.997	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.997	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.997	0.003
G20 Parkinson's disease	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.000	0.997	0.003
J06.0 Acute laryngopharyngitis	0.003	0.997	0.000
C71.9 Brain, unspecified	0.000	0.997	0.003
C71.0 Cerebrum, except lobes and ventricles	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.003	0.997	0.000
D75 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
N02.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
N04.9 Unspecified	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.003	0.997	0.000
C71.3 Parietal lobe	0.000	0.997	0.003
L72.0 Epidermal cyst	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Z71.9 Counselling, unspecified	0.003	0.997	0.000
S62.51 Fracture of thumb (open)	0.000	0.997	0.003
Z71.8 Other specified counselling	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
M25.51 Pain in joint (Shoulder region)	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
S62.5 Fracture of thumb	0.000	0.997	0.003
N08 Glomerular disorders in diseases classified elsewhere	0.003	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.997	0.003
G63.8 Polyneuropathy in other diseases classified elsewhere	0.003	0.997	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.003	0.997	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.003	0.997	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations