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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4713106
log Bayes Factor = 15.1624
Chromosome 6   position 27,444,714  (GRCh37) Explore rs4713106 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90 Intestinal malabsorption
0.000 0.709 0.291
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.766 0.234
E10.9 Without complications
0.000 0.788 0.212
E10 Insulin-dependent diabetes mellitus
0.000 0.791 0.209
K90.3 Pancreatic steatorrhoea
0.000 0.791 0.208
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.791 0.208
K90.1 Tropical sprue
0.000 0.791 0.208
K90.8 Other intestinal malabsorption
0.000 0.799 0.201
E10.5 With peripheral circulatory complications
0.000 0.814 0.186
E10.6 With other specified complications
0.000 0.814 0.185
E10.4 With neurological complications
0.000 0.815 0.185
E10.8 With unspecified complications
0.000 0.828 0.172
E10.1 With ketoacidosis
0.000 0.840 0.160
E10.7 With multiple complications
0.000 0.850 0.150
E10.2 With renal complications
0.000 0.854 0.146
E83 Disorders of mineral metabolism
0.000 0.857 0.142
E10.0 With coma
0.000 0.858 0.142
E10-E14 Diabetes mellitus
0.000 0.861 0.139
E10.3 With ophthalmic complications
0.000 0.862 0.138
E13 Other specified diabetes mellitus
0.000 0.881 0.119
E13.9 Without complications
0.000 0.895 0.105
E14 Unspecified diabetes mellitus
0.000 0.897 0.103
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.898 0.102
E83.8 Other disorders of mineral metabolism
0.000 0.898 0.102
E83.2 Disorders of zinc metabolism
0.000 0.898 0.102
E83.0 Disorders of copper metabolism
0.000 0.898 0.102
E12 Malnutrition-related diabetes mellitus
0.000 0.900 0.100
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.906 0.094
E14.3 With ophthalmic complications
0.000 0.906 0.094
E70-E90 Metabolic disorders
0.000 0.908 0.092
K90.9 Intestinal malabsorption, unspecified
0.001 0.913 0.087
E13.8 With unspecified complications
0.000 0.914 0.085
E13.7 With multiple complications
0.000 0.914 0.085
E13.6 With other specified complications
0.000 0.914 0.085
E13.5 With peripheral circulatory complications
0.000 0.914 0.085
E13.4 With neurological complications
0.000 0.914 0.085
E13.2 With renal complications
0.000 0.914 0.085
E13.1 With ketoacidosis
0.000 0.914 0.085
E13.0 With coma
0.000 0.914 0.085
E13.3 With ophthalmic complications
0.000 0.916 0.083
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.917 0.083
E88 Other metabolic disorders
0.000 0.918 0.082
E40-E46 Malnutrition
0.000 0.919 0.080
E14.6 With other specified complications
0.000 0.921 0.079
E14.5 With peripheral circulatory complications
0.000 0.922 0.077
E16 Other disorders of pancreatic internal secretion
0.000 0.925 0.075
E14.7 With multiple complications
0.000 0.926 0.074
E14.2 Withrenal complications
0.000 0.926 0.074
E14.0 With coma
0.000 0.926 0.074
E85 Amyloidosis
0.000 0.927 0.073
E14.4 With neurological complications
0.000 0.928 0.072
E12.9 Without complications
0.000 0.928 0.072
E12.8 With unspecified complications
0.000 0.928 0.072
E12.7 With multiple complications
0.000 0.928 0.072
E12.6 With other specified complications
0.000 0.928 0.072
E12.5 With peripheral circulatory complications
0.000 0.928 0.072
E12.4 With neurological complications
0.000 0.928 0.072
E12.3 With ophthalmic complications
0.000 0.928 0.072
E12.2 With renal complications
0.000 0.928 0.072
E12.1 With ketoacidosis
0.000 0.928 0.072
E12.0 With coma
0.000 0.928 0.072
E16.2 Hypoglycaemia, unspecified
0.000 0.928 0.072
E46 Unspecified protein-energy malnutrition
0.000 0.929 0.071
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.930 0.070
E84 Cystic fibrosis
0.000 0.934 0.066
E77 Disorders of glycoprotein metabolism
0.000 0.934 0.066
E76 Disorders of glycosaminoglycan metabolism
0.000 0.934 0.066
E72 Other disorders of amino-acid metabolism
0.000 0.934 0.066
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.934 0.066
E70 Disorders of aromatic amino-acid metabolism
0.000 0.934 0.066
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.934 0.066
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.934 0.066
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.934 0.066
E65-E68 Obesity and other hyperalimentation
0.000 0.935 0.065
E88.8 Other specified metabolic disorders
0.000 0.935 0.065
E88.2 Lipomatosis, not elsewhere classified
0.000 0.935 0.065
E14.1 With ketoacidosis
0.000 0.937 0.063
E83.3 Disorders of phosphorus metabolism
0.000 0.937 0.063
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.937 0.063
E79 Disorders of purine and pyrimidine metabolism
0.000 0.937 0.063
E14.8 With unspecified complications
0.000 0.938 0.062
E85.9 Amyloidosis, unspecified
0.000 0.940 0.060
E88.3 Tumour lysis syndrome
0.000 0.940 0.060
E15 Nondiabetic hypoglycaemic coma
0.000 0.940 0.059
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.941 0.059
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.942 0.058
E45 Retarded development following protein-energy malnutrition
0.000 0.942 0.058
E43 Unspecified severe protein-energy malnutrition
0.000 0.942 0.058
E42 Marasmic kwashiorkor
0.000 0.942 0.058
E41 Nutritional marasmus
0.000 0.942 0.058
E40 Kwashiorkor
0.000 0.942 0.058
E14.9 Without complications
0.000 0.943 0.057
E65 Localised adiposity
0.000 0.944 0.056
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.944 0.056
E85.4 Organ-limited amyloidosis
0.000 0.944 0.056
E88.9 Metabolic disorder, unspecified
0.000 0.945 0.055
E89.2 Postprocedural hypoparathyroidism
0.000 0.945 0.055
E83.4 Disorders of magnesium metabolism
0.000 0.946 0.054
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.946 0.054
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.946 0.054
E16.4 Abnormal secretion of gastrin
0.000 0.946 0.054
E16.3 Increased secretion of glucagon
0.000 0.946 0.054
E85.8 Other amyloidosis
0.000 0.947 0.053
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.947 0.053
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.947 0.053
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.947 0.053
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.949 0.051
E74 Other disorders of carbohydrate metabolism
0.000 0.950 0.050
E85.3 Secondary systemic amyloidosis
0.000 0.951 0.049
E73 Lactose intolerance
0.000 0.951 0.048
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.952 0.047
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.952 0.047
E70.3 Albinism
0.000 0.952 0.047
E70.2 Disorders of tyrosine metabolism
0.000 0.952 0.047
E70.1 Other hyperphenylalaninaemias
0.000 0.952 0.047
E70.0 Classical phenylketonuria
0.000 0.952 0.047
E71.3 Disorders of fatty-acid metabolism
0.000 0.952 0.047
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.952 0.047
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.952 0.047
E71.0 Maple-syrup-urine disease
0.000 0.952 0.047
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.952 0.047
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.952 0.047
E72.5 Disorders of glycine metabolism
0.000 0.952 0.047
E72.4 Disorders of ornithine metabolism
0.000 0.952 0.047
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.952 0.047
E72.2 Disorders of urea cycle metabolism
0.000 0.952 0.047
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.952 0.047
E72.0 Disorders of amino-acid transport
0.000 0.952 0.047
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.952 0.047
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.952 0.047
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.952 0.047
E76.2 Other mucopolysaccharidoses
0.000 0.952 0.047
E76.1 Mucopolysaccharidosis, type II
0.000 0.952 0.047
E76.0 Mucopolysaccharidosis, type I
0.000 0.952 0.047
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.952 0.047
E77.8 Other disorders of glycoprotein metabolism
0.000 0.952 0.047
E77.1 Defects in glycoprotein degradation
0.000 0.952 0.047
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.952 0.047
E84.9 Cystic fibrosis, unspecified
0.000 0.952 0.047
E84.8 Cystic fibrosis with other manifestations
0.000 0.952 0.047
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.952 0.047
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.952 0.047
E89.4 Postprocedural ovarian failure
0.000 0.953 0.047
E75.6 Lipid storage disorder, unspecified
0.000 0.953 0.047
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.953 0.047
E75.3 Sphingolipidosis, unspecified
0.000 0.953 0.047
E75.2 Other sphingolipidosis
0.000 0.953 0.047
E75.1 Other gangliosidosis
0.000 0.953 0.047
E75.0 GM2 gangliosidosis
0.000 0.953 0.047
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.953 0.047
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.953 0.047
E89.5 Postprocedural testicular hypofunction
0.000 0.953 0.047
E89.1 Postprocedural hypoinsulinaemia
0.000 0.953 0.047
E67 Other hyperalimentation
0.000 0.953 0.047
E68 Sequelae of hyperalimentation
0.000 0.953 0.047
E89.0 Postprocedural hypothyroidism
0.000 0.953 0.047
E75.5 Other lipid storage disorders
0.000 0.953 0.047
E11 Non-insulin-dependent diabetes mellitus
0.000 0.953 0.047
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.955 0.045
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.955 0.045
E79.1 Lesch-Nyhan syndrome
0.000 0.955 0.045
E50-E64 Other nutritional deficiencies
0.000 0.955 0.044
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.957 0.042
E80.5 Crigler-Najjar syndrome
0.000 0.957 0.042
E80.3 Defects of catalase and peroxydase
0.000 0.957 0.042
E80.1 Porphyria cutanea tarda
0.000 0.957 0.042
E80.0 Hereditary erythropoietic porphyria
0.000 0.957 0.042
E44.1 Mild protein-energy malnutrition
0.000 0.958 0.042
E44.0 Moderate protein-energy malnutrition
0.000 0.958 0.042
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.958 0.041
E80.4 Gilbert's syndrome
0.000 0.958 0.041
E80.2 Other porphyria
0.000 0.959 0.041
E80.6 Other disorders of bilirubin metabolism
0.000 0.961 0.039
E16.1 Other hypoglycaemia
0.000 0.961 0.039
E00-E07 Disorders of thyroid gland
0.000 0.963 0.037
E11.8 With unspecified complications
0.000 0.964 0.036
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.964 0.036
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.964 0.036
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.964 0.036
E74.2 Disorders of galactose metabolism
0.000 0.964 0.036
E74.1 Disorders of fructose metabolism
0.000 0.964 0.036
E11.5 With peripheral circulatory complications
0.000 0.964 0.036
E11.2 With renal complications
0.000 0.964 0.036
E73.8 Other lactose intolerance
0.000 0.965 0.035
E73.1 Secondary lactase deficiency
0.000 0.965 0.035
E73.0 Congenital lactase deficiency
0.000 0.965 0.035
E67.8 Other specified hyperalimentation
0.000 0.966 0.034
E67.3 Hypervitaminosis D
0.000 0.966 0.034
E67.2 Megavitamin-B6 syndrome
0.000 0.966 0.034
E67.1 Hypercarotenaemia
0.000 0.966 0.034
E67.0 Hypervitaminosis A
0.000 0.966 0.034
E11.4 With neurological complications
0.000 0.966 0.034
E53 Deficiency of other B group vitamins
0.000 0.966 0.034
E11.7 With multiple complications
0.000 0.966 0.034
E11.0 With coma
0.000 0.966 0.034
E74.0 Glycogen storage disease
0.000 0.967 0.033
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.968 0.032
E63 Other nutritional deficiencies
0.000 0.968 0.032
E56 Other vitamin deficiencies
0.000 0.968 0.032
E50 Vitamin A deficiency
0.000 0.968 0.032
E60 Dietary zinc deficiency
0.000 0.968 0.032
E59 Dietary selenium deficiency
0.000 0.968 0.032
E54 Ascorbic acid deficiency
0.000 0.968 0.032
E52 Niacin deficiency [pellagra]
0.000 0.968 0.032
E58 Dietary calcium deficiency
0.000 0.968 0.032
E11.6 With other specified complications
0.000 0.969 0.031
E51 Thiamine deficiency
0.000 0.970 0.030
E07 Other disorders of thyroid
0.000 0.970 0.030
E83.5 Disorders of calcium metabolism
0.000 0.971 0.029
E55 Vitamin D deficiency
0.000 0.971 0.029
E11.1 With ketoacidosis
0.000 0.971 0.029
E06 Thyroiditis
0.000 0.972 0.028
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.973 0.026
E00 Congenital iodine-deficiency syndrome
0.000 0.973 0.026
E53.8 Deficiency of other specified B group vitamins
0.000 0.974 0.026
E89.3 Postprocedural hypopituitarism
0.000 0.974 0.025
E07.9 Disorder of thyroid, unspecified
0.000 0.974 0.026
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.975 0.024
E53.1 Pyridoxine deficiency
0.000 0.975 0.024
E53.0 Riboflavin deficiency
0.000 0.975 0.024
E66 Obesity
0.000 0.975 0.025
E53.9 Vitamin B deficiency, unspecified
0.000 0.975 0.024
E50.9 Vitamin A deficiency, unspecified
0.000 0.977 0.023
E50.8 Other manifestations of vitamin A deficiency
0.000 0.977 0.023
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.977 0.023
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.977 0.023
E50.5 Vitamin A deficiency with night blindness
0.000 0.977 0.023
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.977 0.023
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.977 0.023
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.977 0.023
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.977 0.023
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.977 0.023
E56.9 Vitamin deficiency, unspecified
0.000 0.977 0.023
E56.8 Deficiency of other vitamins
0.000 0.977 0.023
E56.1 Deficiency of vitamin K
0.000 0.977 0.023
E56.0 Deficiency of vitamin E
0.000 0.977 0.023
E63.9 Nutritional deficiency, unspecified
0.000 0.977 0.023
E63.8 Other specified nutritional deficiencies
0.000 0.977 0.023
E63.1 Imbalance of constituents of food intake
0.000 0.977 0.023
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.977 0.023
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.977 0.023
E64.8 Sequelae of other nutritional deficiencies
0.000 0.977 0.023
E64.3 Sequelae of rickets
0.000 0.977 0.023
E64.2 Sequelae of vitamin C deficiency
0.000 0.977 0.023
E64.1 Sequelae of vitamin A deficiency
0.000 0.977 0.023
E64.0 Sequelae of protein-energy malnutrition
0.000 0.977 0.023
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.977 0.023
E11.3 With ophthalmic complications
0.000 0.977 0.023
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.977 0.023
E06.3 Autoimmune thyroiditis
0.000 0.977 0.023
E04 Other non-toxic goitre
0.000 0.977 0.023
E51.9 Thiamine deficiency, unspecified
0.000 0.978 0.021
E51.8 Other manifestations of thiamine deficiency
0.000 0.978 0.021
E51.1 Beriberi
0.000 0.978 0.021
E07.1 Dyshormogenetic goitre
0.000 0.979 0.021
E07.0 Hypersecretion of calcitonin
0.000 0.979 0.021
E55.0 Rickets, active
0.000 0.979 0.021
E87.3 Alkalosis
0.000 0.979 0.021
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.979 0.021
E06.5 Other chronic thyroiditis
0.000 0.980 0.020
E06.4 Drug-induced thyroiditis
0.000 0.980 0.020
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.980 0.020
E06.1 Subacute thyroiditis
0.000 0.980 0.020
E06.0 Acute thyroiditis
0.000 0.980 0.020
E20-E35 Disorders of other endocrine glands
0.000 0.980 0.020
E87.0 Hyperosmolality and hypernatraemia
0.000 0.981 0.019
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.981 0.019
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.981 0.019
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.981 0.019
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.981 0.019
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.981 0.019
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.981 0.019
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.981 0.019
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.981 0.019
E51.2 Wernicke's encephalopathy
0.000 0.981 0.019
E07.8 Other specified disorders of thyroid
0.000 0.981 0.019
E06.9 Thyroiditis, unspecified
0.000 0.981 0.019
E04.9 Non-toxic goitre, unspecified
0.000 0.981 0.019
E03 Other hypothyroidism
0.000 0.981 0.019
K90-K93 Other diseases of the digestive system
0.000 0.982 0.018
E66.1 Drug-induced obesity
0.000 0.982 0.018
E55.9 Vitamin D deficiency, unspecified
0.000 0.982 0.018
E04.0 Non-toxic diffuse goitre
0.000 0.982 0.018
E73.9 Lactose intolerance, unspecified
0.001 0.982 0.017
E61 Deficiency of other nutrient elements
0.001 0.982 0.017
E66.0 Obesity due to excess calories
0.000 0.983 0.017
C71.2 Temporal lobe
0.017 0.983 0.000
E87.2 Acidosis
0.000 0.983 0.017
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.983 0.017
E87.4 Mixed disorder of acid-base balance
0.000 0.983 0.017
E04.8 Other specified non-toxic goitre
0.000 0.983 0.017
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.984 0.016
C71 Malignant neoplasm of brain
0.016 0.984 0.000
C71.9 Brain, unspecified
0.016 0.984 0.000
M41.9 Scoliosis, unspecified
0.016 0.984 0.000
E87.5 Hyperkalaemia
0.000 0.984 0.016
E03.8 Other specified hypothyroidism
0.000 0.984 0.016
E20 Hypoparathyroidism
0.000 0.985 0.015
E26 Hyperaldosteronism
0.000 0.985 0.015
M41.99 Scoliosis, unspecified (Site unspecified)
0.015 0.985 0.000
R52.1 Chronic intractable pain
0.015 0.985 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.985 0.015
E32 Diseases of thymus
0.000 0.985 0.015
E31 Polyglandular dysfunction
0.000 0.985 0.015
E30 Disorders of puberty, not elsewhere classified
0.000 0.985 0.015
E25 Adrenogenital disorders
0.000 0.985 0.015
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.015 0.985 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.985 0.015
M41.94 Scoliosis, unspecified (Thoracic region)
0.015 0.985 0.000
E24 Cushing's syndrome
0.000 0.985 0.014
E87.7 Fluid overload
0.000 0.985 0.015
E23.2 Diabetes insipidus
0.000 0.986 0.014
E28 Ovarian dysfunction
0.000 0.986 0.014
M41.96 Scoliosis, unspecified (Lumbar region)
0.014 0.986 0.000
E34 Other endocrine disorders
0.000 0.986 0.014
E29 Testicular dysfunction
0.000 0.986 0.014
E04.1 Non-toxic single thyroid nodule
0.000 0.986 0.014
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.986 0.014
E03.5 Myxoedema coma
0.000 0.986 0.013
E03.4 Atrophy of thyroid (acquired)
0.000 0.986 0.013
E03.3 Postinfectious hypothyroidism
0.000 0.986 0.013
E03.1 Congenital hypothyroidism without goitre
0.000 0.986 0.013
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.986 0.013
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.987 0.013
C71.1 Frontal lobe
0.013 0.987 0.000
G44.2 Tension-type headache
0.013 0.987 0.000
C71.3 Parietal lobe
0.013 0.987 0.000
E78.4 Other hyperlipidaemia
0.000 0.987 0.013
E61.9 Deficiency of nutrient element, unspecified
0.001 0.987 0.012
E61.8 Deficiency of other specified nutrient elements
0.001 0.987 0.012
E61.7 Deficiency of multiple nutrient elements
0.001 0.987 0.012
E61.6 Vanadium deficiency
0.001 0.987 0.012
E61.5 Molybdenum deficiency
0.001 0.987 0.012
E61.4 Chromium deficiency
0.001 0.987 0.012
E61.3 Manganese deficiency
0.001 0.987 0.012
E61.0 Copper deficiency
0.001 0.987 0.012
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.987 0.013
E78.6 Lipoprotein deficiency
0.000 0.987 0.013
E78.3 Hyperchylomicronaemia
0.000 0.987 0.012
C71.7 Brain stem
0.012 0.988 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.988 0.012
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.988 0.012
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.012 0.988 0.000
C71.6 Cerebellum
0.012 0.988 0.000
C71.5 Cerebral ventricle
0.012 0.988 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.988 0.012
C71.0 Cerebrum, except lobes and ventricles
0.012 0.988 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.988 0.012
C71.8 Overlapping lesion of brain
0.012 0.988 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.988 0.012
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.011 0.988 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.011 0.988 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.011 0.988 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.011 0.988 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.989 0.011
E26.0 Primary hyperaldosteronism
0.000 0.989 0.011
E20.8 Other hypoparathyroidism
0.000 0.989 0.011
E20.1 Pseudohypoparathyroidism
0.000 0.989 0.011
E20.0 Idiopathic hypoparathyroidism
0.000 0.989 0.011
E26.9 Hyperaldosteronism, unspecified
0.000 0.989 0.011
E26.8 Other hyperaldosteronism
0.000 0.989 0.011
E26.1 Secondary hyperaldosteronism
0.000 0.989 0.011
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.989 0.011
E25.9 Adrenogenital disorder, unspecified
0.000 0.989 0.011
E25.8 Other adrenogenital disorders
0.000 0.989 0.011
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.989 0.011
E30.9 Disorder of puberty, unspecified
0.000 0.989 0.011
E30.8 Other disorders of puberty
0.000 0.989 0.011
E30.1 Precocious puberty
0.000 0.989 0.011
E30.0 Delayed puberty
0.000 0.989 0.011
E31.9 Polyglandular dysfunction, unspecified
0.000 0.989 0.011
E31.8 Other polyglandular dysfunction
0.000 0.989 0.011
E31.1 Polyglandular hyperfunction
0.000 0.989 0.011
E31.0 Autoimmune polyglandular failure
0.000 0.989 0.011
E32.9 Disease of thymus, unspecified
0.000 0.989 0.011
E32.8 Other diseases of thymus
0.000 0.989 0.011
E32.1 Abscess of thymus
0.000 0.989 0.011
E32.0 Persistent hyperplasia of thymus
0.000 0.989 0.011
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.989 0.011
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.989 0.011
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.989 0.011
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.989 0.011
E23.1 Drug-induced hypopituitarism
0.000 0.989 0.011
E24.8 Other Cushing's syndrome
0.000 0.989 0.011
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.989 0.011
E24.3 Ectopic ACTH syndrome
0.000 0.989 0.011
E24.1 Nelson's syndrome
0.000 0.989 0.011
G31.8 Other specified degenerative diseases of nervous system
0.000 0.989 0.011
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.010 0.989 0.000
E05.8 Other thyrotoxicosis
0.000 0.989 0.010
E28.9 Ovarian dysfunction, unspecified
0.000 0.989 0.010
E28.8 Other ovarian dysfunction
0.000 0.989 0.010
E28.1 Androgen excess
0.000 0.989 0.010
E28.0 Oestrogen excess
0.000 0.989 0.010
E34.8 Other specified endocrine disorders
0.000 0.989 0.010
E34.5 Androgen resistance syndrome
0.000 0.990 0.010
E34.4 Constitutional tall stature
0.000 0.990 0.010
E34.3 Short stature, not elsewhere classified
0.000 0.990 0.010
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.990 0.010
E34.1 Other hypersecretion of intestinal hormones
0.000 0.990 0.010
E78.2 Mixed hyperlipidaemia
0.000 0.990 0.010
E34.9 Endocrine disorder, unspecified
0.000 0.990 0.010
E29.9 Testicular dysfunction, unspecified
0.000 0.990 0.010
E29.8 Other testicular dysfunction
0.000 0.990 0.010
E29.0 Testicular hyperfunction
0.000 0.990 0.010
E61.2 Magnesium deficiency
0.001 0.990 0.010
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.990 0.010
E23.7 Disorder of pituitary gland, unspecified
0.000 0.990 0.010
E27 Other disorders of adrenal gland
0.000 0.990 0.010
E05.5 Thyroid crisis or storm
0.000 0.990 0.010
E05.4 Thyrotoxicosis factitia
0.000 0.990 0.010
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.990 0.010
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.990 0.010
E66.9 Obesity, unspecified
0.000 0.990 0.010
E24.0 Pituitary-dependent Cushing's disease
0.000 0.990 0.010
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.010 0.990 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.990 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.990 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.990 0.010
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.990 0.010
E86 Volume depletion
0.000 0.990 0.010
E27.1 Primary adrenocortical insufficiency
0.000 0.990 0.010
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.990 0.010
E34.0 Carcinoid syndrome
0.000 0.990 0.009
G31.0 Circumscribed brain atrophy
0.000 0.991 0.009
E29.1 Testicular hypofunction
0.000 0.991 0.009
C71.4 Occipital lobe
0.009 0.991 0.000
E23.6 Other disorders of pituitary gland
0.000 0.991 0.009
E21.3 Hyperparathyroidism, unspecified
0.000 0.991 0.009
C69 Malignant neoplasm of eye and adnexa
0.009 0.991 0.000
M41 Scoliosis
0.009 0.991 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.991 0.008
E21.4 Other specified disorders of parathyroid gland
0.000 0.992 0.008
E21.2 Other hyperparathyroidism
0.000 0.992 0.008
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.992 0.008
C70 Malignant neoplasm of meninges
0.008 0.992 0.000
C69.3 Choroid
0.008 0.992 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.992 0.008
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.992 0.007
G30 Alzheimer's disease
0.000 0.992 0.008
E27.5 Adrenomedullary hyperfunction
0.000 0.992 0.007
E27.0 Other adrenocortical overactivity
0.000 0.992 0.007
G30-G32 Other degenerative diseases of the nervous system
0.000 0.993 0.007
E28.3 Primary ovarian failure
0.000 0.993 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.993 0.007
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.007 0.993 0.000
C69.9 Eye, unspecified
0.007 0.993 0.000
K22.8 Other specified diseases of oesophagus
0.007 0.993 0.000
E22 Hyperfunction of pituitary gland
0.000 0.993 0.007
G30.9 Alzheimer's disease, unspecified
0.000 0.993 0.007
C69.6 Orbit
0.007 0.993 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.993 0.007
G44 Other headache syndromes
0.007 0.993 0.000
C69.8 Overlapping lesion of eye and adnexa
0.007 0.993 0.000
C69.5 Lachrymal gland and duct
0.007 0.993 0.000
C69.4 Ciliary body
0.007 0.993 0.000
C69.2 Retina
0.007 0.993 0.000
C69.1 Cornea
0.007 0.993 0.000
M41.5 Other secondary scoliosis
0.006 0.993 0.000
M41.4 Neuromuscular scoliosis
0.006 0.993 0.000
M41.3 Thoracogenic scoliosis
0.006 0.993 0.000
M41.2 Other idiopathic scoliosis
0.006 0.993 0.000
M41.1 Juvenile idiopathic scoliosis
0.006 0.993 0.000
M41.0 Infantile idiopathic scoliosis
0.006 0.993 0.000
M79.10 Myalgia (Multiple sites)
0.007 0.993 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.993 0.006
C69.0 Conjunctiva
0.006 0.994 0.000
C70.0 Cerebral meninges
0.006 0.994 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.994 0.006
E21.0 Primary hyperparathyroidism
0.000 0.994 0.006
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.994 0.006
E78.8 Other disorders of lipoprotein metabolism
0.000 0.994 0.006
G44.8 Other specified headache syndromes
0.006 0.994 0.000
C70.9 Meninges, unspecified
0.006 0.994 0.000
C70.1 Spinal meninges
0.006 0.994 0.000
E27.2 Addisonian crisis
0.000 0.994 0.006
M67.8 Other specified disorders of synovium and tendon
0.000 0.994 0.006
G30.8 Other Alzheimer's disease
0.000 0.994 0.006
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.006 0.994 0.000
G30.1 Alzheimer's disease with late onset
0.000 0.994 0.006
M41.8 Other forms of scoliosis
0.005 0.994 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.006 0.994 0.000
K62.5 Haemorrhage of anus and rectum
0.006 0.994 0.000
C72.9 Central nervous system, unspecified
0.005 0.995 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.005 0.995 0.000
C72.5 Other and unspecified cranial nerves
0.005 0.995 0.000
C72.4 Acoustic nerve
0.005 0.995 0.000
C72.3 Optic nerve
0.005 0.995 0.000
C72.2 Olfactory nerve
0.005 0.995 0.000
C72.1 Cauda equina
0.005 0.995 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.995 0.005
E22.8 Other hyperfunction of pituitary gland
0.000 0.995 0.005
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.995 0.005
E23.0 Hypopituitarism
0.000 0.995 0.005
E61.1 Iron deficiency
0.001 0.995 0.004
M40-M43 Deforming dorsopathies
0.005 0.995 0.000
C72.0 Spinal cord
0.005 0.995 0.000
G44.1 Vascular headache, not elsewhere classified
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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