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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4713110
log Bayes Factor = 19.2877
Chromosome 6   position 27,477,726  (GRCh37) Explore rs4713110 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.592 0.408
E10.9 Without complications
0.000 0.595 0.405
E10.6 With other specified complications
0.000 0.631 0.369
E10.5 With peripheral circulatory complications
0.000 0.633 0.367
E10.4 With neurological complications
0.000 0.639 0.361
E10.3 With ophthalmic complications
0.000 0.654 0.346
E10.1 With ketoacidosis
0.000 0.658 0.342
E10.8 With unspecified complications
0.000 0.669 0.331
E10.7 With multiple complications
0.000 0.707 0.293
E10.2 With renal complications
0.000 0.707 0.293
E10.0 With coma
0.000 0.707 0.293
E10-E14 Diabetes mellitus
0.000 0.750 0.250
K90 Intestinal malabsorption
0.000 0.759 0.241
E83 Disorders of mineral metabolism
0.000 0.785 0.215
E13 Other specified diabetes mellitus
0.000 0.792 0.208
E12 Malnutrition-related diabetes mellitus
0.000 0.821 0.179
E13.9 Without complications
0.000 0.822 0.178
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.823 0.177
K90.3 Pancreatic steatorrhoea
0.000 0.827 0.173
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.827 0.173
K90.1 Tropical sprue
0.000 0.827 0.173
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.830 0.170
E70-E90 Metabolic disorders
0.000 0.832 0.168
K90.8 Other intestinal malabsorption
0.000 0.835 0.164
E88 Other metabolic disorders
0.000 0.838 0.162
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.842 0.158
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.845 0.154
E83.8 Other disorders of mineral metabolism
0.000 0.845 0.154
E83.2 Disorders of zinc metabolism
0.000 0.845 0.154
E83.0 Disorders of copper metabolism
0.000 0.845 0.154
E13.3 With ophthalmic complications
0.000 0.849 0.150
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.849 0.151
E13.8 With unspecified complications
0.000 0.850 0.149
E13.7 With multiple complications
0.000 0.850 0.149
E13.6 With other specified complications
0.000 0.850 0.149
E13.5 With peripheral circulatory complications
0.000 0.850 0.149
E13.4 With neurological complications
0.000 0.850 0.149
E13.2 With renal complications
0.000 0.850 0.149
E13.1 With ketoacidosis
0.000 0.850 0.149
E13.0 With coma
0.000 0.850 0.149
E16 Other disorders of pancreatic internal secretion
0.000 0.851 0.149
E16.2 Hypoglycaemia, unspecified
0.000 0.856 0.144
E11 Non-insulin-dependent diabetes mellitus
0.000 0.857 0.143
E40-E46 Malnutrition
0.000 0.860 0.140
E14 Unspecified diabetes mellitus
0.000 0.862 0.138
E85 Amyloidosis
0.000 0.871 0.129
E12.9 Without complications
0.000 0.871 0.129
E12.8 With unspecified complications
0.000 0.871 0.129
E12.7 With multiple complications
0.000 0.871 0.129
E12.6 With other specified complications
0.000 0.871 0.129
E12.5 With peripheral circulatory complications
0.000 0.871 0.129
E12.4 With neurological complications
0.000 0.871 0.129
E12.3 With ophthalmic complications
0.000 0.871 0.129
E12.2 With renal complications
0.000 0.871 0.129
E12.1 With ketoacidosis
0.000 0.871 0.129
E12.0 With coma
0.000 0.871 0.129
E88.8 Other specified metabolic disorders
0.000 0.872 0.128
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.872 0.128
E14.3 With ophthalmic complications
0.000 0.872 0.128
E88.2 Lipomatosis, not elsewhere classified
0.000 0.874 0.126
E88.3 Tumour lysis syndrome
0.000 0.878 0.121
E84 Cystic fibrosis
0.000 0.879 0.121
E77 Disorders of glycoprotein metabolism
0.000 0.879 0.121
E76 Disorders of glycosaminoglycan metabolism
0.000 0.879 0.121
E72 Other disorders of amino-acid metabolism
0.000 0.879 0.121
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.879 0.121
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.879 0.121
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.879 0.121
E11.2 With renal complications
0.000 0.880 0.120
E46 Unspecified protein-energy malnutrition
0.000 0.882 0.118
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.884 0.116
E11.0 With coma
0.000 0.885 0.115
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.885 0.115
E15 Nondiabetic hypoglycaemic coma
0.000 0.887 0.113
E70 Disorders of aromatic amino-acid metabolism
0.000 0.887 0.113
E11.1 With ketoacidosis
0.000 0.889 0.111
E11.4 With neurological complications
0.000 0.889 0.111
E79 Disorders of purine and pyrimidine metabolism
0.000 0.893 0.107
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.893 0.107
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.893 0.107
E16.4 Abnormal secretion of gastrin
0.000 0.893 0.107
E16.3 Increased secretion of glucagon
0.000 0.893 0.107
E83.3 Disorders of phosphorus metabolism
0.000 0.894 0.106
E88.9 Metabolic disorder, unspecified
0.000 0.895 0.105
E85.9 Amyloidosis, unspecified
0.000 0.896 0.104
E14.5 With peripheral circulatory complications
0.000 0.896 0.103
E11.7 With multiple complications
0.000 0.898 0.102
E11.8 With unspecified complications
0.000 0.899 0.101
E11.5 With peripheral circulatory complications
0.000 0.899 0.101
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.900 0.100
E45 Retarded development following protein-energy malnutrition
0.000 0.900 0.100
E43 Unspecified severe protein-energy malnutrition
0.000 0.900 0.100
E42 Marasmic kwashiorkor
0.000 0.900 0.100
E41 Nutritional marasmus
0.000 0.900 0.100
E40 Kwashiorkor
0.000 0.900 0.100
E14.7 With multiple complications
0.000 0.901 0.099
E14.2 Withrenal complications
0.000 0.901 0.099
E14.0 With coma
0.000 0.901 0.099
E85.4 Organ-limited amyloidosis
0.000 0.906 0.094
E14.6 With other specified complications
0.000 0.906 0.094
E11.6 With other specified complications
0.000 0.907 0.093
E85.8 Other amyloidosis
0.000 0.907 0.093
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.907 0.093
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.907 0.093
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.907 0.093
E73 Lactose intolerance
0.000 0.907 0.093
E65-E68 Obesity and other hyperalimentation
0.000 0.907 0.093
E14.4 With neurological complications
0.000 0.910 0.090
E14.1 With ketoacidosis
0.000 0.910 0.089
E85.3 Secondary systemic amyloidosis
0.000 0.911 0.088
E74 Other disorders of carbohydrate metabolism
0.000 0.912 0.087
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.912 0.087
E71.3 Disorders of fatty-acid metabolism
0.000 0.913 0.087
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.913 0.087
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.913 0.087
E71.0 Maple-syrup-urine disease
0.000 0.913 0.087
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.913 0.087
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.913 0.087
E72.5 Disorders of glycine metabolism
0.000 0.913 0.087
E72.4 Disorders of ornithine metabolism
0.000 0.913 0.087
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.913 0.087
E72.2 Disorders of urea cycle metabolism
0.000 0.913 0.087
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.913 0.087
E72.0 Disorders of amino-acid transport
0.000 0.913 0.087
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.913 0.087
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.913 0.087
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.913 0.087
E76.2 Other mucopolysaccharidoses
0.000 0.913 0.087
E76.1 Mucopolysaccharidosis, type II
0.000 0.913 0.087
E76.0 Mucopolysaccharidosis, type I
0.000 0.913 0.087
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.913 0.087
E77.8 Other disorders of glycoprotein metabolism
0.000 0.913 0.087
E77.1 Defects in glycoprotein degradation
0.000 0.913 0.087
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.913 0.087
E84.9 Cystic fibrosis, unspecified
0.000 0.913 0.087
E84.8 Cystic fibrosis with other manifestations
0.000 0.913 0.087
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.913 0.087
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.913 0.087
K90.9 Intestinal malabsorption, unspecified
0.000 0.914 0.085
E80.4 Gilbert's syndrome
0.000 0.915 0.084
E75.6 Lipid storage disorder, unspecified
0.000 0.916 0.083
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.916 0.083
E75.3 Sphingolipidosis, unspecified
0.000 0.916 0.083
E75.2 Other sphingolipidosis
0.000 0.916 0.083
E75.1 Other gangliosidosis
0.000 0.916 0.083
E75.0 GM2 gangliosidosis
0.000 0.916 0.083
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.918 0.082
E80.5 Crigler-Najjar syndrome
0.000 0.918 0.082
E80.3 Defects of catalase and peroxydase
0.000 0.918 0.082
E80.1 Porphyria cutanea tarda
0.000 0.918 0.082
E80.0 Hereditary erythropoietic porphyria
0.000 0.918 0.082
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.919 0.081
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.919 0.081
E70.2 Disorders of tyrosine metabolism
0.000 0.919 0.081
E70.1 Other hyperphenylalaninaemias
0.000 0.919 0.081
E70.0 Classical phenylketonuria
0.000 0.919 0.081
E80.6 Other disorders of bilirubin metabolism
0.000 0.920 0.080
E75.5 Other lipid storage disorders
0.000 0.921 0.079
E83.4 Disorders of magnesium metabolism
0.000 0.922 0.078
E16.1 Other hypoglycaemia
0.000 0.922 0.077
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.923 0.077
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.923 0.077
E79.1 Lesch-Nyhan syndrome
0.000 0.923 0.077
E80.2 Other porphyria
0.000 0.924 0.076
E65 Localised adiposity
0.000 0.926 0.074
E70.3 Albinism
0.000 0.927 0.073
E44.1 Mild protein-energy malnutrition
0.000 0.928 0.072
E44.0 Moderate protein-energy malnutrition
0.000 0.928 0.072
E11.3 With ophthalmic complications
0.000 0.928 0.072
E14.8 With unspecified complications
0.000 0.929 0.071
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.933 0.067
E73.8 Other lactose intolerance
0.000 0.933 0.067
E73.1 Secondary lactase deficiency
0.000 0.933 0.067
E73.0 Congenital lactase deficiency
0.000 0.933 0.067
E67 Other hyperalimentation
0.000 0.933 0.067
E68 Sequelae of hyperalimentation
0.000 0.933 0.067
E89.4 Postprocedural ovarian failure
0.000 0.934 0.066
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.934 0.066
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.935 0.065
E89.2 Postprocedural hypoparathyroidism
0.000 0.937 0.063
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.937 0.063
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.937 0.063
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.937 0.063
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.937 0.063
E74.2 Disorders of galactose metabolism
0.000 0.937 0.063
E74.1 Disorders of fructose metabolism
0.000 0.937 0.063
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.937 0.063
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.937 0.063
E89.5 Postprocedural testicular hypofunction
0.000 0.937 0.063
E89.1 Postprocedural hypoinsulinaemia
0.000 0.937 0.063
E50-E64 Other nutritional deficiencies
0.000 0.940 0.060
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.943 0.057
E74.0 Glycogen storage disease
0.000 0.943 0.056
R31 Unspecified haematuria
0.056 0.944 0.000
E00-E07 Disorders of thyroid gland
0.000 0.945 0.055
E89.0 Postprocedural hypothyroidism
0.000 0.945 0.055
E78.2 Mixed hyperlipidaemia
0.000 0.949 0.051
E78.4 Other hyperlipidaemia
0.000 0.951 0.049
E87.0 Hyperosmolality and hypernatraemia
0.000 0.951 0.049
E78.1 Pure hyperglyceridaemia
0.000 0.951 0.049
E78.3 Hyperchylomicronaemia
0.000 0.951 0.048
E87.5 Hyperkalaemia
0.000 0.952 0.048
E67.8 Other specified hyperalimentation
0.000 0.952 0.048
E67.3 Hypervitaminosis D
0.000 0.952 0.048
E67.2 Megavitamin-B6 syndrome
0.000 0.952 0.048
E67.1 Hypercarotenaemia
0.000 0.952 0.048
E67.0 Hypervitaminosis A
0.000 0.952 0.048
E78.6 Lipoprotein deficiency
0.000 0.954 0.046
E87.3 Alkalosis
0.000 0.954 0.046
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.956 0.043
E63 Other nutritional deficiencies
0.000 0.956 0.043
E50 Vitamin A deficiency
0.000 0.956 0.043
E60 Dietary zinc deficiency
0.000 0.956 0.043
E59 Dietary selenium deficiency
0.000 0.956 0.043
E54 Ascorbic acid deficiency
0.000 0.956 0.043
E52 Niacin deficiency [pellagra]
0.000 0.956 0.043
E58 Dietary calcium deficiency
0.000 0.957 0.043
E56 Other vitamin deficiencies
0.000 0.958 0.042
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.958 0.041
E51 Thiamine deficiency
0.000 0.959 0.041
E87.7 Fluid overload
0.000 0.959 0.041
E53 Deficiency of other B group vitamins
0.000 0.959 0.041
E87.4 Mixed disorder of acid-base balance
0.000 0.959 0.041
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.960 0.039
E00 Congenital iodine-deficiency syndrome
0.000 0.960 0.039
E06 Thyroiditis
0.000 0.961 0.039
E73.9 Lactose intolerance, unspecified
0.001 0.961 0.038
E07 Other disorders of thyroid
0.000 0.961 0.039
E04 Other non-toxic goitre
0.000 0.962 0.038
E55 Vitamin D deficiency
0.000 0.964 0.036
E83.5 Disorders of calcium metabolism
0.000 0.964 0.035
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.966 0.034
E04.9 Non-toxic goitre, unspecified
0.000 0.966 0.034
E89.3 Postprocedural hypopituitarism
0.000 0.967 0.032
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.967 0.032
E53.9 Vitamin B deficiency, unspecified
0.000 0.968 0.032
E50.9 Vitamin A deficiency, unspecified
0.000 0.969 0.031
E50.8 Other manifestations of vitamin A deficiency
0.000 0.969 0.031
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.969 0.031
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.969 0.031
E50.5 Vitamin A deficiency with night blindness
0.000 0.969 0.031
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.969 0.031
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.969 0.031
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.969 0.031
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.969 0.031
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.969 0.031
E63.9 Nutritional deficiency, unspecified
0.000 0.969 0.031
E63.8 Other specified nutritional deficiencies
0.000 0.969 0.031
E63.1 Imbalance of constituents of food intake
0.000 0.969 0.031
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.969 0.031
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.969 0.031
E64.8 Sequelae of other nutritional deficiencies
0.000 0.969 0.031
E64.3 Sequelae of rickets
0.000 0.969 0.031
E64.2 Sequelae of vitamin C deficiency
0.000 0.969 0.031
E64.1 Sequelae of vitamin A deficiency
0.000 0.969 0.031
E64.0 Sequelae of protein-energy malnutrition
0.000 0.969 0.031
E20-E35 Disorders of other endocrine glands
0.000 0.969 0.031
E56.9 Vitamin deficiency, unspecified
0.000 0.970 0.030
E56.8 Deficiency of other vitamins
0.000 0.970 0.030
E56.0 Deficiency of vitamin E
0.000 0.970 0.030
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.970 0.030
E51.9 Thiamine deficiency, unspecified
0.000 0.970 0.030
E51.8 Other manifestations of thiamine deficiency
0.000 0.970 0.030
E51.1 Beriberi
0.000 0.970 0.030
E53.1 Pyridoxine deficiency
0.000 0.970 0.030
E53.0 Riboflavin deficiency
0.000 0.970 0.030
E04.0 Non-toxic diffuse goitre
0.000 0.971 0.029
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.971 0.029
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.971 0.028
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.971 0.028
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.971 0.028
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.971 0.028
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.971 0.028
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.971 0.028
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.971 0.028
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.971 0.028
E56.1 Deficiency of vitamin K
0.000 0.971 0.028
E07.9 Disorder of thyroid, unspecified
0.000 0.971 0.029
E06.5 Other chronic thyroiditis
0.000 0.972 0.028
E06.4 Drug-induced thyroiditis
0.000 0.972 0.028
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.972 0.028
E06.1 Subacute thyroiditis
0.000 0.972 0.028
E06.0 Acute thyroiditis
0.000 0.972 0.028
E06.3 Autoimmune thyroiditis
0.000 0.972 0.028
E07.1 Dyshormogenetic goitre
0.000 0.972 0.028
E07.0 Hypersecretion of calcitonin
0.000 0.972 0.028
E06.9 Thyroiditis, unspecified
0.000 0.972 0.028
E51.2 Wernicke's encephalopathy
0.000 0.972 0.027
E04.8 Other specified non-toxic goitre
0.000 0.972 0.027
E07.8 Other specified disorders of thyroid
0.000 0.973 0.026
E55.0 Rickets, active
0.000 0.974 0.026
E87.2 Acidosis
0.000 0.974 0.026
E27.1 Primary adrenocortical insufficiency
0.000 0.975 0.025
E86 Volume depletion
0.000 0.975 0.025
E03 Other hypothyroidism
0.000 0.976 0.024
E20 Hypoparathyroidism
0.000 0.976 0.024
E53.8 Deficiency of other specified B group vitamins
0.000 0.976 0.024
E27 Other disorders of adrenal gland
0.000 0.976 0.024
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.976 0.023
E26 Hyperaldosteronism
0.000 0.977 0.023
E05.8 Other thyrotoxicosis
0.000 0.977 0.023
E29 Testicular dysfunction
0.000 0.977 0.023
E61 Deficiency of other nutrient elements
0.001 0.977 0.022
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.978 0.022
E32 Diseases of thymus
0.000 0.978 0.022
E31 Polyglandular dysfunction
0.000 0.978 0.022
E30 Disorders of puberty, not elsewhere classified
0.000 0.978 0.022
E25 Adrenogenital disorders
0.000 0.978 0.022
E14.9 Without complications
0.000 0.978 0.022
E05.5 Thyroid crisis or storm
0.000 0.978 0.022
E05.4 Thyrotoxicosis factitia
0.000 0.978 0.022
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.978 0.022
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.978 0.022
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.978 0.022
E78.8 Other disorders of lipoprotein metabolism
0.001 0.978 0.021
E24 Cushing's syndrome
0.000 0.979 0.021
E04.1 Non-toxic single thyroid nodule
0.000 0.980 0.020
E34 Other endocrine disorders
0.000 0.980 0.020
E20.9 Hypoparathyroidism, unspecified
0.000 0.980 0.020
E03.8 Other specified hypothyroidism
0.000 0.981 0.019
M25.57 Pain in joint (Ankle and foot)
0.000 0.981 0.019
E55.9 Vitamin D deficiency, unspecified
0.000 0.981 0.019
E26.0 Primary hyperaldosteronism
0.000 0.982 0.018
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.982 0.018
E24.2 Drug-induced Cushing's syndrome
0.000 0.982 0.018
E03.5 Myxoedema coma
0.000 0.982 0.018
E03.4 Atrophy of thyroid (acquired)
0.000 0.982 0.018
E03.3 Postinfectious hypothyroidism
0.000 0.982 0.018
E03.1 Congenital hypothyroidism without goitre
0.000 0.982 0.018
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.982 0.018
E20.8 Other hypoparathyroidism
0.000 0.982 0.018
E20.1 Pseudohypoparathyroidism
0.000 0.982 0.018
E20.0 Idiopathic hypoparathyroidism
0.000 0.982 0.018
E23 Hypofunction and other disorders of pituitary gland
0.000 0.982 0.018
E04.2 Non-toxic multinodular goitre
0.000 0.982 0.018
E28 Ovarian dysfunction
0.000 0.983 0.017
E27.5 Adrenomedullary hyperfunction
0.000 0.983 0.017
E27.0 Other adrenocortical overactivity
0.000 0.983 0.017
M25.5 Pain in joint
0.000 0.983 0.017
E26.9 Hyperaldosteronism, unspecified
0.000 0.983 0.017
E26.8 Other hyperaldosteronism
0.000 0.983 0.017
E26.1 Secondary hyperaldosteronism
0.000 0.983 0.017
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.983 0.017
E66 Obesity
0.000 0.983 0.017
E29.1 Testicular hypofunction
0.000 0.983 0.017
E29.9 Testicular dysfunction, unspecified
0.000 0.983 0.016
E29.8 Other testicular dysfunction
0.000 0.983 0.016
E29.0 Testicular hyperfunction
0.000 0.983 0.016
E61.9 Deficiency of nutrient element, unspecified
0.001 0.984 0.016
E61.8 Deficiency of other specified nutrient elements
0.001 0.984 0.016
E61.7 Deficiency of multiple nutrient elements
0.001 0.984 0.016
E61.6 Vanadium deficiency
0.001 0.984 0.016
E61.5 Molybdenum deficiency
0.001 0.984 0.016
E61.4 Chromium deficiency
0.001 0.984 0.016
E61.3 Manganese deficiency
0.001 0.984 0.016
E61.0 Copper deficiency
0.001 0.984 0.016
G31.8 Other specified degenerative diseases of nervous system
0.000 0.984 0.016
E25.9 Adrenogenital disorder, unspecified
0.000 0.984 0.016
E25.8 Other adrenogenital disorders
0.000 0.984 0.016
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.984 0.016
E30.9 Disorder of puberty, unspecified
0.000 0.984 0.016
E30.8 Other disorders of puberty
0.000 0.984 0.016
E30.1 Precocious puberty
0.000 0.984 0.016
E30.0 Delayed puberty
0.000 0.984 0.016
E31.9 Polyglandular dysfunction, unspecified
0.000 0.984 0.016
E31.8 Other polyglandular dysfunction
0.000 0.984 0.016
E31.1 Polyglandular hyperfunction
0.000 0.984 0.016
E31.0 Autoimmune polyglandular failure
0.000 0.984 0.016
E32.9 Disease of thymus, unspecified
0.000 0.984 0.016
E32.8 Other diseases of thymus
0.000 0.984 0.016
E32.1 Abscess of thymus
0.000 0.984 0.016
E32.0 Persistent hyperplasia of thymus
0.000 0.984 0.016
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.984 0.016
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.984 0.016
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.984 0.016
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.984 0.016
K90-K93 Other diseases of the digestive system
0.000 0.984 0.016
E23.2 Diabetes insipidus
0.000 0.984 0.016
E24.8 Other Cushing's syndrome
0.000 0.985 0.015
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.985 0.015
E24.3 Ectopic ACTH syndrome
0.000 0.985 0.015
E24.1 Nelson's syndrome
0.000 0.985 0.015
M25.51 Pain in joint (Shoulder region)
0.000 0.985 0.015
E34.5 Androgen resistance syndrome
0.000 0.985 0.014
E34.4 Constitutional tall stature
0.000 0.985 0.014
E34.3 Short stature, not elsewhere classified
0.000 0.985 0.014
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.985 0.014
E34.1 Other hypersecretion of intestinal hormones
0.000 0.985 0.014
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.986 0.014
G31.0 Circumscribed brain atrophy
0.000 0.986 0.014
M25.58 Pain in joint (Other)
0.000 0.986 0.014
E27.2 Addisonian crisis
0.000 0.986 0.014
E34.0 Carcinoid syndrome
0.000 0.986 0.014
M25.52 Pain in joint (Upper arm)
0.000 0.986 0.014
E24.0 Pituitary-dependent Cushing's disease
0.000 0.986 0.014
G30 Alzheimer's disease
0.000 0.986 0.014
E34.8 Other specified endocrine disorders
0.000 0.986 0.013
E34.9 Endocrine disorder, unspecified
0.000 0.986 0.013
G30-G32 Other degenerative diseases of the nervous system
0.000 0.987 0.013
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.987 0.013
E23.1 Drug-induced hypopituitarism
0.000 0.987 0.013
G30.9 Alzheimer's disease, unspecified
0.000 0.987 0.013
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.987 0.013
E28.9 Ovarian dysfunction, unspecified
0.000 0.987 0.013
E28.8 Other ovarian dysfunction
0.000 0.987 0.013
E28.1 Androgen excess
0.000 0.987 0.013
E28.0 Oestrogen excess
0.000 0.987 0.013
E61.2 Magnesium deficiency
0.001 0.987 0.012
E28.2 Polycystic ovarian syndrome
0.000 0.987 0.013
G30.0 Alzheimer's disease with early onset
0.000 0.987 0.013
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.987 0.012
E23.7 Disorder of pituitary gland, unspecified
0.000 0.988 0.012
E66.1 Drug-induced obesity
0.000 0.988 0.012
G44.2 Tension-type headache
0.012 0.988 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.988 0.012
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.988 0.012
M25.54 Pain in joint (Hand)
0.000 0.989 0.011
E27.8 Other specified disorders of adrenal gland
0.000 0.989 0.011
E87.6 Hypokalaemia
0.000 0.989 0.011
M25.53 Pain in joint (Forearm)
0.000 0.989 0.011
G30.8 Other Alzheimer's disease
0.000 0.989 0.011
E24.9 Cushing's syndrome, unspecified
0.000 0.989 0.011
E66.0 Obesity due to excess calories
0.000 0.989 0.011
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.989 0.011
E23.6 Other disorders of pituitary gland
0.000 0.989 0.010
G30.1 Alzheimer's disease with late onset
0.000 0.990 0.010
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.990 0.009
E27.9 Disorder of adrenal gland, unspecified
0.001 0.991 0.008
G31.2 Degeneration of nervous system due to alcohol
0.000 0.991 0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.991 0.008
K93.1 Megacolon in Chagas' disease
0.000 0.991 0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.991 0.008
M25.59 Pain in joint (Site unspecified)
0.000 0.992 0.008
E21.4 Other specified disorders of parathyroid gland
0.000 0.992 0.008
E21.2 Other hyperparathyroidism
0.000 0.992 0.008
E28.3 Primary ovarian failure
0.001 0.992 0.007
E22 Hyperfunction of pituitary gland
0.000 0.992 0.008
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.993 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.993 0.007
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.993 0.007
E21.3 Hyperparathyroidism, unspecified
0.000 0.993 0.007
G44 Other headache syndromes
0.007 0.993 0.000
K22.8 Other specified diseases of oesophagus
0.006 0.994 0.000
E21.0 Primary hyperparathyroidism
0.000 0.994 0.006
E22.8 Other hyperfunction of pituitary gland
0.000 0.994 0.006
E61.1 Iron deficiency
0.001 0.994 0.005
G44.8 Other specified headache syndromes
0.006 0.994 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.994 0.005
G82.5 Tetraplegia, unspecified
0.000 0.995 0.005
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.995 0.005
E23.0 Hypopituitarism
0.000 0.995 0.005
G44.0 Cluster headache syndrome
0.005 0.995 0.000
E22.1 Hyperprolactinaemia
0.000 0.995 0.005
G44.1 Vascular headache, not elsewhere classified
0.005 0.995 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.005 0.995 0.000
M25.50 Pain in joint (Multiple sites)
0.000 0.995 0.005
E11.9 Without complications
0.000 0.995 0.005
G82.4 Spastic tetraplegia
0.000 0.995 0.005
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.005 0.995 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.005 0.995 0.000
G82 Paraplegia and tetraplegia
0.000 0.995 0.005
M41.9 Scoliosis, unspecified
0.005 0.995 0.000
K02.9 Dental caries, unspecified
0.000 0.995 0.005
N60.1 Diffuse cystic mastopathy
0.000 0.995 0.005
G44.3 Chronic posttraumatic headache
0.005 0.995 0.000
G82.1 Spastic paraplegia
0.000 0.995 0.005
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
K02.8 Other dental caries
0.000 0.996 0.004
Z34.9 Supervision of normal pregnancy, unspecified
0.004 0.996 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.996 0.004
M41.96 Scoliosis, unspecified (Lumbar region)
0.004 0.996 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.004 0.996 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.996 0.004
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.996 0.004
K02 Dental caries
0.000 0.996 0.004
M94.86 Other specified disorders of cartilage (Lower leg)
0.004 0.996 0.000
C71.2 Temporal lobe
0.004 0.996 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.004 0.996 0.000
G82.3 Flaccid tetraplegia
0.000 0.996 0.004
G82.0 Flaccid paraplegia
0.000 0.996 0.004
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.004 0.996 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.004 0.996 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.004 0.996 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.004 0.996 0.000
M79.10 Myalgia (Multiple sites)
0.004 0.996 0.000
E66.9 Obesity, unspecified
0.000 0.996 0.004
E22.0 Acromegaly and pituitary gigantism
0.001 0.996 0.003
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.997 0.003
K02.1 Caries of dentin
0.000 0.997 0.003
E05.9 Thyrotoxicosis, unspecified
0.000 0.997 0.003
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.003 0.997 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.997 0.003
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.997 0.003
R30.0 Dysuria
0.003 0.997 0.000
K56.4 Other impaction of intestine
0.003 0.997 0.000
N04.9 Unspecified
0.000 0.997 0.003
G82.2 Paraplegia, unspecified
0.000 0.997 0.003
K02.5 Caries with pulp exposure
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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