TreeWAS – Variant ID: rs4713389

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10.9 Without complications	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.002	0.998
E10-E14 Diabetes mellitus	0.000	0.003	0.997
T36-T50 Poisoning by drugs, medicaments and biological substances	0.993	0.007	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.991	0.009	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.011	0.989
E50-E64 Other nutritional deficiencies	0.000	0.013	0.987
L40.0 Psoriasis vulgaris	0.986	0.014	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.977	0.023	0.000
E53 Deficiency of other B group vitamins	0.000	0.024	0.976
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.969	0.031	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.031	0.969
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.966	0.034	0.000
E10.4 With neurological complications	0.000	0.041	0.959
T43.2 Other and unspecified antidepressants	0.957	0.043	0.000
E10.3 With ophthalmic complications	0.000	0.043	0.957
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.955	0.045	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.937	0.063	0.000
E10.5 With peripheral circulatory complications	0.000	0.074	0.926
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.917	0.083	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.912	0.088	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.903	0.097	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.902	0.098	0.000
L40.1 Generalised pustular psoriasis	0.888	0.112	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.879	0.121	0.000
T39.1 4-Aminophenol derivatives	0.879	0.121	0.000
T42.4 Benzodiazepines	0.866	0.134	0.000
E06 Thyroiditis	0.000	0.138	0.862
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.845	0.155	0.000
E10.2 With renal complications	0.000	0.164	0.836
T43.4 Butyrophenone and thioxanthene neuroleptics	0.819	0.181	0.000
E55 Vitamin D deficiency	0.000	0.199	0.801
T50.6 Antidotes and chelating agents, not elsewhere classified	0.792	0.208	0.000
T43.6 Psychostimulants with abuse potential	0.786	0.214	0.000
E06.3 Autoimmune thyroiditis	0.000	0.219	0.781
L40.8 Other psoriasis	0.778	0.222	0.000
E10.6 With other specified complications	0.000	0.222	0.778
E10.8 With unspecified complications	0.000	0.229	0.771
E05.8 Other thyrotoxicosis	0.000	0.230	0.770
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.237	0.763
T46 Poisoning by agents primarily affecting the cardiovascular system	0.753	0.247	0.000
E10.0 With coma	0.000	0.251	0.749
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.724	0.276	0.000
T39.0 Salicylates	0.722	0.278	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.285	0.715
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.712	0.288	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.712	0.288	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.712	0.288	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.712	0.288	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.712	0.288	0.000
E04 Other non-toxic goitre	0.000	0.289	0.711
T43.9 Psychotropic drug, unspecified	0.710	0.289	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.710	0.289	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.710	0.289	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.292	0.708
E63 Other nutritional deficiencies	0.000	0.292	0.708
E56 Other vitamin deficiencies	0.000	0.292	0.708
E51 Thiamine deficiency	0.000	0.292	0.708
E50 Vitamin A deficiency	0.000	0.292	0.708
E60 Dietary zinc deficiency	0.000	0.292	0.708
E59 Dietary selenium deficiency	0.000	0.292	0.708
E58 Dietary calcium deficiency	0.000	0.292	0.708
E54 Ascorbic acid deficiency	0.000	0.292	0.708
E52 Niacin deficiency [pellagra]	0.000	0.292	0.708
T36 Poisoning by systemic antibiotics	0.708	0.292	0.000
E61 Deficiency of other nutrient elements	0.000	0.295	0.705
T47.0 Histamine H(2)-receptor antagonists	0.704	0.296	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.700	0.300	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.700	0.300	0.000
T42.3 Barbiturates	0.700	0.300	0.000
T42.2 Succinimides and oxazolidinediones	0.700	0.300	0.000
T42.0 Hydantoin derivatives	0.700	0.300	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.300	0.700
E53.1 Pyridoxine deficiency	0.000	0.300	0.700
E53.0 Riboflavin deficiency	0.000	0.300	0.700
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.696	0.304	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.695	0.305	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.695	0.305	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.695	0.305	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.695	0.305	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.695	0.305	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.695	0.305	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.695	0.305	0.000
T44.0 Anticholinesterase agents	0.695	0.305	0.000
T50.8 Diagnostic agents	0.693	0.307	0.000
T50.7 Analeptics and opioid receptor antagonists	0.693	0.307	0.000
T50.5 Appetite depressants	0.693	0.307	0.000
T50.4 Drugs affecting uric acid metabolism	0.693	0.307	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.693	0.307	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.693	0.307	0.000
T50.1 Loop [high-ceiling] diuretics	0.693	0.307	0.000
T50.0 Mineralocorticoids and their antagonists	0.693	0.307	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.324	0.676
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.675	0.325	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.332	0.668
E55.9 Vitamin D deficiency, unspecified	0.000	0.332	0.668
T47.1 Other antacids and anti-gastric-secretion drugs	0.664	0.336	0.000
E07 Other disorders of thyroid	0.000	0.341	0.659
E13 Other specified diabetes mellitus	0.000	0.341	0.659
E10.1 With ketoacidosis	0.000	0.348	0.652
T39.4 Antirheumatics, not elsewhere classified	0.647	0.353	0.000
T39.2 Pyrazolone derivatives	0.647	0.353	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.356	0.644
T43.5 Other and unspecified antipsychotics and neuroleptics	0.640	0.360	0.000
E03.8 Other specified hypothyroidism	0.000	0.364	0.636
K90 Intestinal malabsorption	0.000	0.370	0.630
E06.5 Other chronic thyroiditis	0.000	0.382	0.618
E06.4 Drug-induced thyroiditis	0.000	0.382	0.618
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.382	0.618
E06.1 Subacute thyroiditis	0.000	0.382	0.618
E06.0 Acute thyroiditis	0.000	0.382	0.618
T42.1 Iminostilbenes	0.608	0.392	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.606	0.394	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.606	0.394	0.000
T47.7 Emetics	0.606	0.394	0.000
T47.6 Antidiarrhoeal drugs	0.606	0.394	0.000
T47.5 Digestants	0.606	0.394	0.000
T47.4 Other laxatives	0.606	0.394	0.000
T47.3 Saline and osmotic laxatives	0.606	0.394	0.000
T47.2 Stimulant laxatives	0.606	0.394	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.601	0.399	0.000
T45.0 Antiallergic and antiemetic drugs	0.599	0.401	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.405	0.595
E40-E46 Malnutrition	0.000	0.423	0.576
E55.0 Rickets, active	0.000	0.425	0.574
K90.9 Intestinal malabsorption, unspecified	0.000	0.429	0.571
E06.9 Thyroiditis, unspecified	0.000	0.435	0.565
E15 Nondiabetic hypoglycaemic coma	0.000	0.453	0.547
T46.1 Calcium-channel blockers	0.542	0.458	0.000
T38.1 Thyroid hormones and substitutes	0.541	0.459	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.540	0.460	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.540	0.460	0.000
T46.7 Peripheral vasodilators	0.540	0.460	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.540	0.460	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.540	0.460	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.540	0.460	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.540	0.460	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.470	0.529
E07.9 Disorder of thyroid, unspecified	0.000	0.480	0.520
T38.9 Other and unspecified hormone antagonists	0.519	0.481	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.519	0.481	0.000
T38.7 Androgens and anabolic congeners	0.519	0.481	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.519	0.481	0.000
T38.5 Other oestrogens and progestogens	0.519	0.481	0.000
T38.4 Oral contraceptives	0.519	0.481	0.000
T38.2 Antithyroid drugs	0.519	0.481	0.000
T38.0 Glucocorticoids and synthetic analogues	0.519	0.481	0.000
E61.2 Magnesium deficiency	0.000	0.484	0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.510	0.489	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.510	0.489	0.000
T37.5 Antiviral drugs	0.510	0.489	0.000
T37.4 Anthelminthics	0.510	0.489	0.000
T37.3 Other antiprotozoal drugs	0.510	0.489	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.510	0.489	0.000
T37.1 Antimycobacterial drugs	0.510	0.489	0.000
T37.0 Sulphonamides	0.510	0.489	0.000
T41.5 Therapeutic gases	0.510	0.489	0.000
T41.4 Anaesthetic, unspecified	0.510	0.489	0.000
T41.3 Local anaesthetics	0.510	0.489	0.000
T41.2 Other and unspecified general anaesthetics	0.510	0.489	0.000
T41.1 Intravenous anaesthetics	0.510	0.489	0.000
T41.0 Inhaled anaesthetics	0.510	0.489	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.510	0.489	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.510	0.489	0.000
T48.5 Anti-common-cold drugs	0.510	0.489	0.000
T48.4 Expectorants	0.510	0.489	0.000
T48.3 Antitussives	0.510	0.489	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.510	0.489	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.510	0.489	0.000
T48.0 Oxytocic drugs	0.510	0.489	0.000
T49.9 Topical agent, unspecified	0.510	0.489	0.000
T49.8 Other topical agents	0.510	0.489	0.000
T49.7 Dental drugs, topically applied	0.510	0.489	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.510	0.489	0.000
T49.5 Ophthalmological drugs and preparations	0.510	0.489	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.510	0.489	0.000
T49.3 Emollients, demulcents and protectants	0.510	0.489	0.000
T49.2 Local astringents and local detergents	0.510	0.489	0.000
T49.1 Antipruritics	0.510	0.489	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.510	0.489	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.510	0.489	0.000
T45.8 Other primarily systemic and haematological agents	0.510	0.489	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.510	0.489	0.000
T45.6 Fibrinolysis-affecting drugs	0.510	0.489	0.000
T45.4 Iron and its compounds	0.510	0.489	0.000
T45.3 Enzymes, not elsewhere classified	0.510	0.489	0.000
T45.2 Vitamins, not elsewhere classified	0.510	0.489	0.000
E04.8 Other specified non-toxic goitre	0.000	0.490	0.510
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.508	0.492	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.508	0.492	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.492	0.507
E50.8 Other manifestations of vitamin A deficiency	0.000	0.492	0.507
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.492	0.507
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.492	0.507
E50.5 Vitamin A deficiency with night blindness	0.000	0.492	0.507
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.492	0.507
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.492	0.507
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.492	0.507
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.492	0.507
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.492	0.507
E51.9 Thiamine deficiency, unspecified	0.000	0.492	0.507
E51.8 Other manifestations of thiamine deficiency	0.000	0.492	0.507
E51.2 Wernicke's encephalopathy	0.000	0.492	0.507
E51.1 Beriberi	0.000	0.492	0.507
E56.9 Vitamin deficiency, unspecified	0.000	0.492	0.507
E56.8 Deficiency of other vitamins	0.000	0.492	0.507
E56.1 Deficiency of vitamin K	0.000	0.492	0.507
E56.0 Deficiency of vitamin E	0.000	0.492	0.507
E63.9 Nutritional deficiency, unspecified	0.000	0.492	0.507
E63.8 Other specified nutritional deficiencies	0.000	0.492	0.507
E63.1 Imbalance of constituents of food intake	0.000	0.492	0.507
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.492	0.507
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.492	0.507
E64.8 Sequelae of other nutritional deficiencies	0.000	0.492	0.507
E64.3 Sequelae of rickets	0.000	0.492	0.507
E64.2 Sequelae of vitamin C deficiency	0.000	0.492	0.507
E64.1 Sequelae of vitamin A deficiency	0.000	0.492	0.507
E64.0 Sequelae of protein-energy malnutrition	0.000	0.492	0.507
T36.9 Systemic antibiotic, unspecified	0.507	0.492	0.000
T36.8 Other systemic antibiotics	0.507	0.492	0.000
T36.7 Antifungal antibiotics, systemically used	0.507	0.492	0.000
T36.6 Rifamycins	0.507	0.492	0.000
T36.5 Aminoglycosides	0.507	0.492	0.000
T36.4 Tetracyclines	0.507	0.492	0.000
T36.3 Macrolides	0.507	0.492	0.000
T36.2 Chloramphenicol group	0.507	0.492	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.507	0.492	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.494	0.506
E61.8 Deficiency of other specified nutrient elements	0.000	0.494	0.506
E61.7 Deficiency of multiple nutrient elements	0.000	0.494	0.506
E61.6 Vanadium deficiency	0.000	0.494	0.506
E61.5 Molybdenum deficiency	0.000	0.494	0.506
E61.4 Chromium deficiency	0.000	0.494	0.506
E61.3 Manganese deficiency	0.000	0.494	0.506
E61.0 Copper deficiency	0.000	0.494	0.506
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.505	0.495	0.000
T36.0 Penicillins	0.503	0.497	0.000
E61.1 Iron deficiency	0.000	0.508	0.491
E07.1 Dyshormogenetic goitre	0.000	0.527	0.472
E07.0 Hypersecretion of calcitonin	0.000	0.527	0.472
E13.8 With unspecified complications	0.000	0.527	0.472
E13.7 With multiple complications	0.000	0.527	0.472
E13.6 With other specified complications	0.000	0.527	0.472
E13.5 With peripheral circulatory complications	0.000	0.527	0.472
E13.4 With neurological complications	0.000	0.527	0.472
E13.3 With ophthalmic complications	0.000	0.527	0.472
E13.2 With renal complications	0.000	0.527	0.472
E13.1 With ketoacidosis	0.000	0.527	0.472
E13.0 With coma	0.000	0.527	0.472
E04.0 Non-toxic diffuse goitre	0.000	0.531	0.469
T45.1 Antineoplastic and immunosuppressive drugs	0.467	0.533	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.540	0.460
K90.3 Pancreatic steatorrhoea	0.000	0.548	0.452
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.548	0.452
K90.1 Tropical sprue	0.000	0.548	0.452
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.559	0.441
E65-E68 Obesity and other hyperalimentation	0.000	0.565	0.435
E16.1 Other hypoglycaemia	0.000	0.569	0.430
M07.30 Other psoriatic arthropathies (Multiple sites)	0.429	0.571	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.572	0.428
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.573	0.426
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.573	0.426
E16.4 Abnormal secretion of gastrin	0.000	0.573	0.426
E16.3 Increased secretion of glucagon	0.000	0.573	0.426
M07.3 Other psoriatic arthropathies	0.422	0.578	0.000
K90.8 Other intestinal malabsorption	0.000	0.579	0.421
E14 Unspecified diabetes mellitus	0.000	0.579	0.420
E13.9 Without complications	0.000	0.583	0.416
T45.5 Anticoagulants	0.416	0.584	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.586	0.413
E45 Retarded development following protein-energy malnutrition	0.000	0.586	0.413
E43 Unspecified severe protein-energy malnutrition	0.000	0.586	0.413
E42 Marasmic kwashiorkor	0.000	0.586	0.413
E41 Nutritional marasmus	0.000	0.586	0.413
E40 Kwashiorkor	0.000	0.586	0.413
M07.39 Other psoriatic arthropathies (Site unspecified)	0.413	0.587	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.356	0.644	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.655	0.345
M07.34 Other psoriatic arthropathies (Hand)	0.343	0.657	0.000
E14.3 With ophthalmic complications	0.000	0.664	0.336
E07.8 Other specified disorders of thyroid	0.001	0.670	0.330
E20-E35 Disorders of other endocrine glands	0.000	0.672	0.328
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.322	0.677	0.000
E67 Other hyperalimentation	0.000	0.688	0.312
E68 Sequelae of hyperalimentation	0.000	0.688	0.312
M07.38 Other psoriatic arthropathies (Other)	0.303	0.697	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.303	0.697	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.303	0.697	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.303	0.697	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.303	0.697	0.000
E14.8 With unspecified complications	0.000	0.698	0.302
E14.7 With multiple complications	0.000	0.698	0.302
E14.6 With other specified complications	0.000	0.698	0.302
E14.2 Withrenal complications	0.000	0.698	0.302
E14.0 With coma	0.000	0.698	0.302
E44.1 Mild protein-energy malnutrition	0.000	0.703	0.296
E44.0 Moderate protein-energy malnutrition	0.000	0.703	0.296
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.296	0.704	0.000
E27 Other disorders of adrenal gland	0.000	0.704	0.296
E14.4 With neurological complications	0.000	0.706	0.294
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.284	0.715	0.001
E27.1 Primary adrenocortical insufficiency	0.000	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.280	0.720	0.000
S80-S89 Injuries to the knee and lower leg	0.279	0.721	0.000
E14.5 With peripheral circulatory complications	0.000	0.725	0.275
E46 Unspecified protein-energy malnutrition	0.001	0.725	0.274
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.270	0.730	0.000
S82 Fracture of lower leg, including ankle	0.269	0.731	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.738	0.262
E14.1 With ketoacidosis	0.000	0.739	0.260
S82.1 Fracture of upper end of tibia	0.255	0.745	0.000
S82.5 Fracture of medial malleolus	0.245	0.755	0.000
S82.10 Fracture of upper end of tibia (closed)	0.244	0.756	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.244	0.756	0.000
E34 Other endocrine disorders	0.000	0.757	0.243
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.243	0.757	0.000
E24 Cushing's syndrome	0.000	0.763	0.237
T25 Burn and corrosion of ankle and foot	0.236	0.763	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.236	0.764	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.765	0.235
E32 Diseases of thymus	0.000	0.765	0.235
E31 Polyglandular dysfunction	0.000	0.765	0.235
E30 Disorders of puberty, not elsewhere classified	0.000	0.765	0.235
E25 Adrenogenital disorders	0.000	0.765	0.235
S10-S19 Injuries to the neck	0.234	0.766	0.000
S82.6 Fracture of lateral malleolus	0.233	0.767	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.231	0.769	0.000
S86 Injury of muscle and tendon at lower leg level	0.230	0.770	0.000
T66-T78 Other and unspecified effects of external causes	0.229	0.771	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.772	0.228
S90-S99 Injuries to the ankle and foot	0.228	0.772	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.228	0.772	0.000
S82.50 Fracture of medial malleolus (closed)	0.227	0.772	0.000
E65 Localised adiposity	0.000	0.773	0.226
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.226	0.774	0.000
E27.2 Addisonian crisis	0.000	0.775	0.225
E67.8 Other specified hyperalimentation	0.000	0.776	0.224
E67.3 Hypervitaminosis D	0.000	0.776	0.224
E67.2 Megavitamin-B6 syndrome	0.000	0.776	0.224
E67.1 Hypercarotenaemia	0.000	0.776	0.224
E67.0 Hypervitaminosis A	0.000	0.776	0.224
E29 Testicular dysfunction	0.000	0.776	0.224
E28 Ovarian dysfunction	0.000	0.779	0.220
T20 Burn and corrosion of head and neck	0.218	0.782	0.000
T21 Burn and corrosion of trunk	0.217	0.783	0.000
S82.0 Fracture of patella	0.217	0.783	0.000
S36 Injury of intra-abdominal organs	0.217	0.783	0.000
S91 Open wound of ankle and foot	0.216	0.784	0.000
T00-T07 Injuries involving multiple body regions	0.215	0.785	0.000
S30.2 Contusion of external genital organs	0.214	0.786	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.213	0.787	0.000
S82.4 Fracture of fibula alone	0.213	0.787	0.000
S81 Open wound of lower leg	0.213	0.787	0.000
T33-T35 Frostbite	0.212	0.788	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.212	0.788	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.788	0.212
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.788	0.212
E27.0 Other adrenocortical overactivity	0.000	0.788	0.212
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.211	0.789	0.000
S32 Fracture of lumbar spine and pelvis	0.210	0.790	0.000
S82.60 Fracture of lateral malleolus (closed)	0.207	0.793	0.000
S31 Open wound of abdomen, lower back and pelvis	0.207	0.793	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.205	0.794	0.001
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.204	0.795	0.001
T40.8 Lysergide [LSD]	0.204	0.795	0.001
T40.7 Cannabis (derivatives)	0.204	0.795	0.001
T40.5 Cocaine	0.204	0.795	0.001
T40.3 Methadone	0.204	0.795	0.001
T40.1 Heroin	0.204	0.795	0.001
T40.0 Opium	0.204	0.795	0.001
E20 Hypoparathyroidism	0.000	0.796	0.203
T79-T79 Certain early complications of trauma	0.202	0.798	0.000
S88 Traumatic amputation of lower leg	0.200	0.799	0.000
S87 Crushing injury of lower leg	0.200	0.799	0.000
S85 Injury of blood vessels at lower leg level	0.200	0.799	0.000
S84 Injury of nerves at lower leg level	0.200	0.799	0.000
S11 Open wound of neck	0.200	0.800	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.200	0.800	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.200	0.800	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.199	0.801	0.000
E22 Hyperfunction of pituitary gland	0.000	0.801	0.199
S91.1 Open wound of toe(s) without damage to nail	0.198	0.802	0.000
S89 Other and unspecified injuries of lower leg	0.197	0.803	0.000
E66 Obesity	0.000	0.803	0.197
T25.0 Burn of unspecified degree of ankle and foot	0.196	0.804	0.000
E34.8 Other specified endocrine disorders	0.000	0.804	0.195
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.194	0.806	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.194	0.806	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.194	0.806	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.194	0.806	0.000
T18 Foreign body in alimentary tract	0.193	0.807	0.000
S82.9 Fracture of lower leg, part unspecified	0.193	0.807	0.000
S10 Superficial injury of neck	0.193	0.807	0.000
T23 Burn and corrosion of wrist and hand	0.192	0.807	0.000
E26 Hyperaldosteronism	0.000	0.809	0.190
T09 Other injuries of spine and trunk, level unspecified	0.190	0.810	0.000
S30.1 Contusion of abdominal wall	0.190	0.810	0.000
M07 Psoriatic and enteropathic arthropathies	0.187	0.811	0.001
E28.3 Primary ovarian failure	0.000	0.812	0.188
T40.6 Other and unspecified narcotics	0.187	0.812	0.001
S82.7 Multiple fractures of lower leg	0.186	0.814	0.000
T11 Other injuries of upper limb, level unspecified	0.186	0.814	0.000
T66 Unspecified effects of radiation	0.185	0.815	0.000
T25.2 Burn of second degree of ankle and foot	0.185	0.815	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.185	0.815	0.000
T75 Effects of other external causes	0.185	0.815	0.000
S99 Other and unspecified injuries of ankle and foot	0.185	0.815	0.000
L40-L45 Papulosquamous disorders	0.183	0.816	0.001
T51 Toxic effect of alcohol	0.183	0.816	0.000
S91.3 Open wound of other parts of foot	0.183	0.817	0.000
S82.11 Fracture of upper end of tibia (open)	0.183	0.817	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.817	0.182
E24.9 Cushing's syndrome, unspecified	0.000	0.818	0.182
S86.8 Injury of other muscles and tendons at lower leg level	0.182	0.818	0.000
S82.00 Fracture of patella (closed)	0.181	0.819	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.180	0.820	0.000
S82.2 Fracture of shaft of tibia	0.179	0.820	0.000
T16 Foreign body in ear	0.179	0.821	0.000
T31 Burns classified according to extent of body surface involved	0.179	0.821	0.000
S19 Other and unspecified injuries of neck	0.179	0.821	0.000
T56 Toxic effect of metals	0.178	0.821	0.000
S37 Injury of urinary and pelvic organs	0.177	0.823	0.000
T13 Other injuries of lower limb, level unspecified	0.177	0.823	0.000
T21.3 Burn of third degree of trunk	0.176	0.824	0.000
S82.51 Fracture of medial malleolus (open)	0.176	0.824	0.000
T90 Sequelae of injuries of head	0.176	0.824	0.000
S32.4 Fracture of acetabulum	0.175	0.825	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.175	0.825	0.000
T20.2 Burn of second degree of head and neck	0.175	0.825	0.000
E34.5 Androgen resistance syndrome	0.000	0.826	0.174
E34.4 Constitutional tall stature	0.000	0.826	0.174
E34.3 Short stature, not elsewhere classified	0.000	0.826	0.174
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.826	0.174
E34.1 Other hypersecretion of intestinal hormones	0.000	0.826	0.174
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.174	0.826	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.174	0.826	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.174	0.826	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.174	0.826	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.174	0.826	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.174	0.826	0.000
T68 Hypothermia	0.173	0.827	0.000
S82.40 Fracture of fibula alone (closed)	0.173	0.827	0.000
S31.4 Open wound of vagina and vulva	0.173	0.827	0.000
T21.2 Burn of second degree of trunk	0.171	0.829	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.171	0.829	0.000
E24.8 Other Cushing's syndrome	0.000	0.830	0.170
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.830	0.170
E24.3 Ectopic ACTH syndrome	0.000	0.830	0.170
E24.1 Nelson's syndrome	0.000	0.830	0.170
E24.0 Pituitary-dependent Cushing's disease	0.000	0.830	0.170
T19 Foreign body in genito-urinary tract	0.170	0.830	0.000
S36.0 Injury of spleen	0.170	0.830	0.000
T25.7 Corrosion of third degree of ankle and foot	0.170	0.830	0.000
T25.6 Corrosion of second degree of ankle and foot	0.170	0.830	0.000
T25.5 Corrosion of first degree of ankle and foot	0.170	0.830	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.170	0.830	0.000
T25.3 Burn of third degree of ankle and foot	0.170	0.830	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations