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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4713411
log Bayes Factor = 67.1016
Chromosome 6   position 30,987,176  (GRCh37) Explore rs4713411 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
E03 Other hypothyroidism
0.000 0.007 0.993
E03.9 Hypothyroidism, unspecified
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
L40.0 Psoriasis vulgaris
0.978 0.022 0.000
G35 Multiple sclerosis
0.000 0.024 0.976
E06 Thyroiditis
0.000 0.064 0.936
K90 Intestinal malabsorption
0.000 0.122 0.878
E06.3 Autoimmune thyroiditis
0.000 0.145 0.855
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.179 0.821
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.194 0.806
E06.9 Thyroiditis, unspecified
0.000 0.196 0.804
E53.8 Deficiency of other specified B group vitamins
0.000 0.228 0.772
E53 Deficiency of other B group vitamins
0.000 0.232 0.768
L40.1 Generalised pustular psoriasis
0.762 0.238 0.000
E50-E64 Other nutritional deficiencies
0.000 0.241 0.758
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.246 0.754
E03.8 Other specified hypothyroidism
0.000 0.256 0.744
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
K90.9 Intestinal malabsorption, unspecified
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.288 0.712
E03.4 Atrophy of thyroid (acquired)
0.000 0.288 0.712
E03.3 Postinfectious hypothyroidism
0.000 0.288 0.712
L40.4 Guttate psoriasis
0.710 0.289 0.000
L40.8 Other psoriasis
0.701 0.299 0.000
K90.8 Other intestinal malabsorption
0.000 0.299 0.701
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.301 0.699
E53.9 Vitamin B deficiency, unspecified
0.000 0.320 0.679
E06.5 Other chronic thyroiditis
0.000 0.327 0.673
E06.4 Drug-induced thyroiditis
0.000 0.329 0.671
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.329 0.671
E06.0 Acute thyroiditis
0.000 0.329 0.671
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.339 0.661
L40.3 Pustulosis palmaris et plantaris
0.658 0.342 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.342 0.658
G37 Other demyelinating diseases of central nervous system
0.000 0.357 0.643
E07 Other disorders of thyroid
0.000 0.362 0.638
E06.1 Subacute thyroiditis
0.000 0.363 0.637
K90.3 Pancreatic steatorrhoea
0.000 0.370 0.630
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.370 0.630
K90.1 Tropical sprue
0.000 0.370 0.630
E04 Other non-toxic goitre
0.000 0.404 0.596
E58 Dietary calcium deficiency
0.000 0.420 0.579
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.421 0.578
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.424 0.576
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.428 0.572
E51 Thiamine deficiency
0.000 0.434 0.566
E05.8 Other thyrotoxicosis
0.000 0.444 0.556
E53.1 Pyridoxine deficiency
0.000 0.449 0.550
E53.0 Riboflavin deficiency
0.000 0.449 0.550
E56 Other vitamin deficiencies
0.000 0.455 0.545
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.456 0.544
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.456 0.544
E63 Other nutritional deficiencies
0.000 0.456 0.544
E50 Vitamin A deficiency
0.000 0.456 0.544
E60 Dietary zinc deficiency
0.000 0.456 0.544
E59 Dietary selenium deficiency
0.000 0.456 0.544
E52 Niacin deficiency [pellagra]
0.000 0.456 0.544
E61 Deficiency of other nutrient elements
0.000 0.465 0.535
E40-E46 Malnutrition
0.000 0.479 0.521
E54 Ascorbic acid deficiency
0.000 0.479 0.521
E04.0 Non-toxic diffuse goitre
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
G36 Other acute disseminated demyelination
0.000 0.499 0.501
E04.2 Non-toxic multinodular goitre
0.000 0.520 0.480
E07.8 Other specified disorders of thyroid
0.000 0.521 0.478
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.525 0.475
G37.5 Concentric sclerosis [Balo]
0.000 0.539 0.461
G37.4 Subacute necrotising myelitis
0.000 0.539 0.461
G37.2 Central pontine myelinolysis
0.000 0.539 0.461
G37.1 Central demyelination of corpus callosum
0.000 0.539 0.461
G37.0 Diffuse sclerosis
0.000 0.539 0.461
E07.1 Dyshormogenetic goitre
0.000 0.542 0.458
E07.0 Hypersecretion of calcitonin
0.000 0.542 0.458
E55 Vitamin D deficiency
0.000 0.543 0.457
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.550 0.450
E51.2 Wernicke's encephalopathy
0.000 0.572 0.428
E04.8 Other specified non-toxic goitre
0.000 0.573 0.427
L40-L45 Papulosquamous disorders
0.411 0.589 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.594 0.406
E51.8 Other manifestations of thiamine deficiency
0.000 0.594 0.406
E51.1 Beriberi
0.000 0.594 0.406
E61.1 Iron deficiency
0.000 0.605 0.395
E56.1 Deficiency of vitamin K
0.000 0.608 0.391
E56.9 Vitamin deficiency, unspecified
0.000 0.609 0.390
E56.8 Deficiency of other vitamins
0.000 0.609 0.390
E56.0 Deficiency of vitamin E
0.000 0.609 0.390
E50.9 Vitamin A deficiency, unspecified
0.000 0.610 0.390
E50.8 Other manifestations of vitamin A deficiency
0.000 0.610 0.390
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.610 0.390
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.610 0.390
E50.5 Vitamin A deficiency with night blindness
0.000 0.610 0.390
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.610 0.390
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.610 0.390
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.610 0.390
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.610 0.390
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.610 0.390
E63.9 Nutritional deficiency, unspecified
0.000 0.610 0.390
E63.8 Other specified nutritional deficiencies
0.000 0.610 0.390
E63.1 Imbalance of constituents of food intake
0.000 0.610 0.390
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.610 0.390
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.610 0.390
E64.8 Sequelae of other nutritional deficiencies
0.000 0.610 0.390
E64.3 Sequelae of rickets
0.000 0.610 0.390
E64.2 Sequelae of vitamin C deficiency
0.000 0.610 0.390
E64.1 Sequelae of vitamin A deficiency
0.000 0.610 0.390
E64.0 Sequelae of protein-energy malnutrition
0.000 0.610 0.390
E61.9 Deficiency of nutrient element, unspecified
0.000 0.616 0.383
E61.8 Deficiency of other specified nutrient elements
0.000 0.616 0.383
E61.7 Deficiency of multiple nutrient elements
0.000 0.616 0.383
E61.6 Vanadium deficiency
0.000 0.616 0.383
E61.5 Molybdenum deficiency
0.000 0.616 0.383
E61.4 Chromium deficiency
0.000 0.616 0.383
E61.3 Manganese deficiency
0.000 0.616 0.383
E61.0 Copper deficiency
0.000 0.616 0.383
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.626 0.373
E45 Retarded development following protein-energy malnutrition
0.000 0.626 0.373
E43 Unspecified severe protein-energy malnutrition
0.000 0.626 0.373
E42 Marasmic kwashiorkor
0.000 0.626 0.373
E41 Nutritional marasmus
0.000 0.626 0.373
E40 Kwashiorkor
0.000 0.626 0.373
E61.2 Magnesium deficiency
0.000 0.638 0.362
G36.9 Acute disseminated demyelination, unspecified
0.000 0.641 0.359
G36.8 Other specified acute disseminated demyelination
0.000 0.641 0.359
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.641 0.359
G36.0 Neuromyelitis optica [Devic]
0.000 0.641 0.359
E46 Unspecified protein-energy malnutrition
0.000 0.647 0.353
E07.9 Disorder of thyroid, unspecified
0.000 0.653 0.346
E65-E68 Obesity and other hyperalimentation
0.000 0.655 0.345
E15 Nondiabetic hypoglycaemic coma
0.000 0.659 0.340
E70-E90 Metabolic disorders
0.000 0.671 0.329
E55.0 Rickets, active
0.000 0.672 0.328
E89.0 Postprocedural hypothyroidism
0.000 0.674 0.326
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.678 0.322
E04.9 Non-toxic goitre, unspecified
0.000 0.679 0.321
L42 Pityriasis rosea
0.306 0.694 0.000
E83.1 Disorders of iron metabolism
0.000 0.695 0.305
L44 Other papulosquamous disorders
0.304 0.695 0.000
E83 Disorders of mineral metabolism
0.000 0.700 0.300
L41 Parapsoriasis
0.294 0.705 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.294 0.705 0.000
E10-E14 Diabetes mellitus
0.000 0.717 0.283
E16 Other disorders of pancreatic internal secretion
0.000 0.726 0.274
E44.1 Mild protein-energy malnutrition
0.000 0.732 0.268
E44.0 Moderate protein-energy malnutrition
0.000 0.732 0.268
L43 Lichen planus
0.265 0.735 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.748 0.252
E67 Other hyperalimentation
0.000 0.752 0.248
E68 Sequelae of hyperalimentation
0.000 0.752 0.248
E10 Insulin-dependent diabetes mellitus
0.000 0.756 0.244
E20-E35 Disorders of other endocrine glands
0.000 0.758 0.242
E10.9 Without complications
0.000 0.758 0.242
E55.9 Vitamin D deficiency, unspecified
0.000 0.759 0.241
E84 Cystic fibrosis
0.000 0.761 0.239
E65 Localised adiposity
0.000 0.761 0.239
E77 Disorders of glycoprotein metabolism
0.000 0.764 0.236
E76 Disorders of glycosaminoglycan metabolism
0.000 0.764 0.236
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.764 0.236
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.764 0.236
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.766 0.234
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.767 0.233
R31 Unspecified haematuria
0.233 0.767 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.769 0.231
E89.1 Postprocedural hypoinsulinaemia
0.000 0.769 0.231
L44.0 Pityriasis rubra pilaris
0.228 0.771 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.772 0.228
E27.1 Primary adrenocortical insufficiency
0.000 0.772 0.228
E70 Disorders of aromatic amino-acid metabolism
0.000 0.774 0.226
E27 Other disorders of adrenal gland
0.000 0.774 0.225
E88 Other metabolic disorders
0.000 0.776 0.224
E85 Amyloidosis
0.000 0.778 0.222
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.780 0.220
L44.9 Papulosquamous disorder, unspecified
0.218 0.781 0.000
L44.8 Other specified papulosquamous disorders
0.218 0.781 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.218 0.781 0.000
L44.3 Lichen ruber moniliformis
0.218 0.781 0.000
L44.2 Lichen striatus
0.218 0.781 0.000
L44.1 Lichen nitidus
0.218 0.781 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.785 0.215
E83.8 Other disorders of mineral metabolism
0.000 0.785 0.215
E83.2 Disorders of zinc metabolism
0.000 0.785 0.215
E83.0 Disorders of copper metabolism
0.000 0.785 0.215
E73 Lactose intolerance
0.000 0.786 0.214
E89.4 Postprocedural ovarian failure
0.000 0.786 0.214
E72 Other disorders of amino-acid metabolism
0.000 0.788 0.212
E10.3 With ophthalmic complications
0.000 0.788 0.212
L41.9 Parapsoriasis, unspecified
0.211 0.789 0.000
L41.8 Other parapsoriasis
0.211 0.789 0.000
L41.5 Retiform parapsoriasis
0.211 0.789 0.000
L41.4 Large plaque parapsoriasis
0.211 0.789 0.000
L41.3 Small plaque parapsoriasis
0.211 0.789 0.000
L41.2 Lymphomatoid papulosis
0.211 0.789 0.000
L41.1 Pityriasis lichenoides chronica
0.211 0.789 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.211 0.789 0.000
E80.4 Gilbert's syndrome
0.000 0.792 0.208
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.793 0.207
E74 Other disorders of carbohydrate metabolism
0.000 0.795 0.205
E12 Malnutrition-related diabetes mellitus
0.000 0.797 0.203
E89.2 Postprocedural hypoparathyroidism
0.000 0.799 0.201
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.803 0.197
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.803 0.197
E16.4 Abnormal secretion of gastrin
0.000 0.803 0.197
E16.3 Increased secretion of glucagon
0.000 0.803 0.197
E89.5 Postprocedural testicular hypofunction
0.000 0.803 0.197
E10.2 With renal complications
0.000 0.805 0.195
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.806 0.194
E80.1 Porphyria cutanea tarda
0.000 0.807 0.193
L43.8 Other lichen planus
0.191 0.809 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.809 0.190
L43.3 Subacute (active) lichen planus
0.190 0.810 0.000
L43.2 Lichenoid drug reaction
0.190 0.810 0.000
L43.1 Bullous lichen planus
0.190 0.810 0.000
L43.0 Hypertrophic lichen planus
0.190 0.810 0.000
E29 Testicular dysfunction
0.000 0.812 0.188
E22 Hyperfunction of pituitary gland
0.000 0.812 0.188
E20 Hypoparathyroidism
0.000 0.816 0.184
E80.6 Other disorders of bilirubin metabolism
0.000 0.819 0.181
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.819 0.180
E80.5 Crigler-Najjar syndrome
0.000 0.819 0.180
E80.3 Defects of catalase and peroxydase
0.000 0.819 0.180
E80.0 Hereditary erythropoietic porphyria
0.000 0.819 0.180
E67.8 Other specified hyperalimentation
0.000 0.822 0.178
E67.3 Hypervitaminosis D
0.000 0.822 0.178
E67.2 Megavitamin-B6 syndrome
0.000 0.822 0.178
E67.1 Hypercarotenaemia
0.000 0.822 0.178
E67.0 Hypervitaminosis A
0.000 0.822 0.178
E31 Polyglandular dysfunction
0.000 0.823 0.177
E84.9 Cystic fibrosis, unspecified
0.000 0.825 0.175
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.826 0.173
E32 Diseases of thymus
0.000 0.826 0.173
E30 Disorders of puberty, not elsewhere classified
0.000 0.826 0.173
E84.8 Cystic fibrosis with other manifestations
0.000 0.828 0.172
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.828 0.172
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.828 0.172
E85.4 Organ-limited amyloidosis
0.000 0.830 0.170
E71.3 Disorders of fatty-acid metabolism
0.000 0.830 0.169
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.830 0.169
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.830 0.169
E71.0 Maple-syrup-urine disease
0.000 0.830 0.169
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.830 0.169
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.830 0.169
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.830 0.169
E76.2 Other mucopolysaccharidoses
0.000 0.830 0.169
E76.1 Mucopolysaccharidosis, type II
0.000 0.830 0.169
E76.0 Mucopolysaccharidosis, type I
0.000 0.830 0.169
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.830 0.169
E77.8 Other disorders of glycoprotein metabolism
0.000 0.830 0.169
E77.1 Defects in glycoprotein degradation
0.000 0.830 0.169
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.830 0.169
E22.1 Hyperprolactinaemia
0.000 0.830 0.170
E88.3 Tumour lysis syndrome
0.000 0.835 0.165
E13 Other specified diabetes mellitus
0.000 0.836 0.164
E85.8 Other amyloidosis
0.000 0.836 0.164
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.836 0.164
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.836 0.164
E79.1 Lesch-Nyhan syndrome
0.000 0.836 0.164
E10.5 With peripheral circulatory complications
0.000 0.837 0.163
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.838 0.162
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.838 0.162
E70.2 Disorders of tyrosine metabolism
0.000 0.838 0.162
E70.1 Other hyperphenylalaninaemias
0.000 0.838 0.162
E70.0 Classical phenylketonuria
0.000 0.838 0.162
E27.5 Adrenomedullary hyperfunction
0.000 0.838 0.162
E27.0 Other adrenocortical overactivity
0.000 0.838 0.162
L43.9 Lichen planus, unspecified
0.160 0.840 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.841 0.159
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.841 0.159
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.841 0.159
E10.7 With multiple complications
0.000 0.843 0.156
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.843 0.156
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.844 0.155
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.845 0.155
E26 Hyperaldosteronism
0.000 0.846 0.154
E88.9 Metabolic disorder, unspecified
0.000 0.846 0.154
E25 Adrenogenital disorders
0.000 0.846 0.154
E73.8 Other lactose intolerance
0.000 0.846 0.153
E73.1 Secondary lactase deficiency
0.000 0.846 0.153
E73.0 Congenital lactase deficiency
0.000 0.846 0.153
E20.9 Hypoparathyroidism, unspecified
0.000 0.847 0.153
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.848 0.152
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.848 0.152
E72.5 Disorders of glycine metabolism
0.000 0.848 0.152
E72.4 Disorders of ornithine metabolism
0.000 0.848 0.152
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.848 0.152
E72.2 Disorders of urea cycle metabolism
0.000 0.848 0.152
E70.3 Albinism
0.000 0.848 0.152
E16.1 Other hypoglycaemia
0.000 0.848 0.151
E29.1 Testicular hypofunction
0.000 0.850 0.150
E83.3 Disorders of phosphorus metabolism
0.000 0.851 0.149
E75.6 Lipid storage disorder, unspecified
0.000 0.851 0.149
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.851 0.149
E75.3 Sphingolipidosis, unspecified
0.000 0.851 0.149
E75.1 Other gangliosidosis
0.000 0.851 0.149
E75.0 GM2 gangliosidosis
0.000 0.851 0.149
E14 Unspecified diabetes mellitus
0.000 0.852 0.148
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.853 0.147
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.853 0.147
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.853 0.147
E74.2 Disorders of galactose metabolism
0.000 0.853 0.147
E74.1 Disorders of fructose metabolism
0.000 0.853 0.147
E74.0 Glycogen storage disease
0.000 0.853 0.147
E72.0 Disorders of amino-acid transport
0.000 0.853 0.146
E27.2 Addisonian crisis
0.000 0.854 0.146
E85.3 Secondary systemic amyloidosis
0.000 0.854 0.146
E88.8 Other specified metabolic disorders
0.000 0.854 0.146
E12.9 Without complications
0.000 0.854 0.146
E12.8 With unspecified complications
0.000 0.854 0.146
E12.7 With multiple complications
0.000 0.854 0.146
E12.6 With other specified complications
0.000 0.854 0.146
E12.5 With peripheral circulatory complications
0.000 0.854 0.146
E12.4 With neurological complications
0.000 0.854 0.146
E12.3 With ophthalmic complications
0.000 0.854 0.146
E12.2 With renal complications
0.000 0.854 0.146
E12.1 With ketoacidosis
0.000 0.854 0.146
E12.0 With coma
0.000 0.854 0.146
E16.2 Hypoglycaemia, unspecified
0.000 0.855 0.145
E22.0 Acromegaly and pituitary gigantism
0.000 0.857 0.143
E10.1 With ketoacidosis
0.000 0.857 0.143
E80.2 Other porphyria
0.000 0.858 0.142
E28 Ovarian dysfunction
0.000 0.858 0.142
E75.5 Other lipid storage disorders
0.000 0.859 0.140
E85.9 Amyloidosis, unspecified
0.000 0.860 0.140
E88.2 Lipomatosis, not elsewhere classified
0.000 0.860 0.140
E14.3 With ophthalmic complications
0.000 0.860 0.140
E10.8 With unspecified complications
0.000 0.861 0.139
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.864 0.136
E29.9 Testicular dysfunction, unspecified
0.000 0.865 0.135
E29.8 Other testicular dysfunction
0.000 0.865 0.135
E29.0 Testicular hyperfunction
0.000 0.865 0.135
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.865 0.135
E22.8 Other hyperfunction of pituitary gland
0.000 0.865 0.135
E10.6 With other specified complications
0.000 0.865 0.135
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.865 0.134
E20.8 Other hypoparathyroidism
0.000 0.868 0.132
E20.0 Idiopathic hypoparathyroidism
0.000 0.868 0.132
E73.9 Lactose intolerance, unspecified
0.000 0.869 0.131
E31.0 Autoimmune polyglandular failure
0.000 0.869 0.130
E75.2 Other sphingolipidosis
0.000 0.869 0.130
E34 Other endocrine disorders
0.000 0.871 0.128
E31.9 Polyglandular dysfunction, unspecified
0.000 0.873 0.127
E31.8 Other polyglandular dysfunction
0.000 0.873 0.127
E31.1 Polyglandular hyperfunction
0.000 0.873 0.127
E30.9 Disorder of puberty, unspecified
0.000 0.875 0.124
E30.8 Other disorders of puberty
0.000 0.875 0.124
E30.1 Precocious puberty
0.000 0.875 0.124
E30.0 Delayed puberty
0.000 0.875 0.124
E32.9 Disease of thymus, unspecified
0.000 0.875 0.124
E32.8 Other diseases of thymus
0.000 0.875 0.124
E32.1 Abscess of thymus
0.000 0.875 0.124
E32.0 Persistent hyperplasia of thymus
0.000 0.875 0.124
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.875 0.124
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.875 0.124
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.875 0.124
E10.4 With neurological complications
0.000 0.880 0.120
E27.9 Disorder of adrenal gland, unspecified
0.000 0.881 0.118
E13.8 With unspecified complications
0.000 0.882 0.118
E13.7 With multiple complications
0.000 0.882 0.118
E13.6 With other specified complications
0.000 0.882 0.118
E13.5 With peripheral circulatory complications
0.000 0.882 0.118
E13.4 With neurological complications
0.000 0.882 0.118
E13.3 With ophthalmic complications
0.000 0.882 0.118
E13.2 With renal complications
0.000 0.882 0.118
E13.1 With ketoacidosis
0.000 0.882 0.118
E13.0 With coma
0.000 0.882 0.118
E28.3 Primary ovarian failure
0.000 0.883 0.117
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.884 0.116
E10.0 With coma
0.000 0.885 0.114
E20.1 Pseudohypoparathyroidism
0.000 0.887 0.113
E26.9 Hyperaldosteronism, unspecified
0.000 0.889 0.111
E26.8 Other hyperaldosteronism
0.000 0.889 0.111
E26.1 Secondary hyperaldosteronism
0.000 0.889 0.111
E25.9 Adrenogenital disorder, unspecified
0.000 0.889 0.110
E25.8 Other adrenogenital disorders
0.000 0.889 0.110
E14.6 With other specified complications
0.000 0.891 0.109
E14.8 With unspecified complications
0.000 0.893 0.107
E14.7 With multiple complications
0.000 0.894 0.106
E14.0 With coma
0.000 0.894 0.106
E24 Cushing's syndrome
0.001 0.895 0.105
E23 Hypofunction and other disorders of pituitary gland
0.000 0.897 0.103
E28.9 Ovarian dysfunction, unspecified
0.000 0.898 0.102
E28.8 Other ovarian dysfunction
0.000 0.898 0.102
E28.1 Androgen excess
0.000 0.898 0.102
E28.0 Oestrogen excess
0.000 0.898 0.102
E14.5 With peripheral circulatory complications
0.000 0.898 0.102
E34.0 Carcinoid syndrome
0.000 0.905 0.095
E34.5 Androgen resistance syndrome
0.000 0.907 0.092
E34.4 Constitutional tall stature
0.000 0.907 0.092
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.907 0.092
E34.1 Other hypersecretion of intestinal hormones
0.000 0.907 0.092
E34.3 Short stature, not elsewhere classified
0.000 0.908 0.092
E26.0 Primary hyperaldosteronism
0.000 0.909 0.091
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.909 0.091
E14.2 Withrenal complications
0.000 0.910 0.090
E14.1 With ketoacidosis
0.000 0.910 0.089
E27.8 Other specified disorders of adrenal gland
0.000 0.913 0.086
E83.4 Disorders of magnesium metabolism
0.000 0.917 0.083
E83.5 Disorders of calcium metabolism
0.000 0.917 0.083
E14.4 With neurological complications
0.000 0.921 0.079
E13.9 Without complications
0.000 0.921 0.078
E23.7 Disorder of pituitary gland, unspecified
0.000 0.923 0.077
E24.0 Pituitary-dependent Cushing's disease
0.001 0.923 0.076
F41.9 Anxiety disorder, unspecified
0.077 0.923 0.000
E66 Obesity
0.000 0.924 0.076
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.924 0.075
E24.3 Ectopic ACTH syndrome
0.001 0.924 0.075
E24.1 Nelson's syndrome
0.001 0.924 0.075
M35.0 Sicca syndrome [Sjogren]
0.000 0.924 0.076
E34.8 Other specified endocrine disorders
0.000 0.925 0.075
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.926 0.074
E23.1 Drug-induced hypopituitarism
0.000 0.926 0.074
E24.2 Drug-induced Cushing's syndrome
0.001 0.928 0.072
E86 Volume depletion
0.000 0.930 0.070
E24.8 Other Cushing's syndrome
0.001 0.930 0.069
E34.9 Endocrine disorder, unspecified
0.000 0.930 0.070
F41 Other anxiety disorders
0.070 0.930 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.069 0.931 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.931 0.068
K90-K93 Other diseases of the digestive system
0.000 0.932 0.068
F41.2 Mixed anxiety and depressive disorder
0.067 0.933 0.000
E23.2 Diabetes insipidus
0.000 0.934 0.066
E23.6 Other disorders of pituitary gland
0.000 0.935 0.065
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.940 0.060
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.943 0.057
E66.1 Drug-induced obesity
0.000 0.945 0.055
E66.8 Other obesity
0.000 0.947 0.053
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.950 0.050
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.951 0.049
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.951 0.049
F41.8 Other specified anxiety disorders
0.048 0.952 0.000
E21.2 Other hyperparathyroidism
0.000 0.955 0.045
E21.4 Other specified disorders of parathyroid gland
0.000 0.959 0.041
F41.3 Other mixed anxiety disorders
0.039 0.960 0.000
M35 Other systemic involvement of connective tissue
0.000 0.961 0.039
E66.0 Obesity due to excess calories
0.000 0.964 0.035
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.964 0.035
K93.1 Megacolon in Chagas' disease
0.000 0.964 0.035
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.964 0.035
J47 Bronchiectasis
0.000 0.966 0.034
E23.0 Hypopituitarism
0.000 0.966 0.034
M35.7 Hypermobility syndrome
0.000 0.967 0.033
M35.1 Other overlap syndromes
0.000 0.970 0.030
E28.2 Polycystic ovarian syndrome
0.001 0.970 0.029
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.971 0.029
E24.9 Cushing's syndrome, unspecified
0.002 0.971 0.028
M35.2 Behcet's disease
0.000 0.971 0.029
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.972 0.028
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.972 0.028
M35.5 Multifocal fibrosclerosis
0.000 0.972 0.028
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.972 0.028
M35.8 Other specified systemic involvement of connective tissue
0.000 0.973 0.027
M35.3 Polymyalgia rheumatica
0.000 0.974 0.026
R30-R39 Symptoms and signs involving the urinary system
0.022 0.978 0.000
C32.0 Glottis
0.022 0.978 0.000
R30 Pain associated with micturition
0.021 0.979 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.979 0.020
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.980 0.020
R30.0 Dysuria
0.020 0.980 0.000
Q61 Cystic kidney disease
0.020 0.980 0.000
Q61.3 Polycystic kidney, unspecified
0.019 0.981 0.000
Q61.0 Congenital single renal cyst
0.019 0.981 0.000
Q61.2 Polycystic kidney, adult type
0.019 0.981 0.000
R34 Anuria and oliguria
0.019 0.981 0.000
F41.1 Generalised anxiety disorder
0.017 0.982 0.000
R30.1 Vesical tenesmus
0.017 0.983 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.984 0.016
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.984 0.016
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.984 0.016
D23.1 Skin of eyelid, including canthus
0.000 0.985 0.015
Q61.4 Renal dysplasia
0.015 0.985 0.000
Q61.9 Cystic kidney disease, unspecified
0.015 0.985 0.000
Q60-Q64 Congenital malformations of the urinary system
0.015 0.985 0.000
E21.0 Primary hyperparathyroidism
0.000 0.985 0.015
Q61.8 Other cystic kidney diseases
0.015 0.985 0.000
Q61.1 Polycystic kidney, infantile type
0.015 0.985 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.985 0.014
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.985 0.014
R39 Other symptoms and signs involving the urinary system
0.015 0.985 0.000
K91.1 Postgastric surgery syndromes
0.000 0.986 0.014
Q60 Renal agenesis and other reduction defects of kidney
0.014 0.986 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.014 0.986 0.000
C32 Malignant neoplasm of larynx
0.013 0.987 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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