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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4713429
log Bayes Factor = 53.4226
Chromosome 6   position 31,021,017  (GRCh37) Explore rs4713429 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
R31 Unspecified haematuria
0.964 0.036 0.000
L40.9 Psoriasis, unspecified
0.000 0.040 0.960
L40 Psoriasis
0.000 0.097 0.903
L40.5 Arthropathic psoriasis
0.000 0.154 0.846
L40.0 Psoriasis vulgaris
0.000 0.166 0.834
K90 Intestinal malabsorption
0.000 0.347 0.653
L40.4 Guttate psoriasis
0.000 0.352 0.647
L40.3 Pustulosis palmaris et plantaris
0.000 0.352 0.647
L40.2 Acrodermatitis continua
0.000 0.352 0.647
L40.1 Generalised pustular psoriasis
0.000 0.352 0.647
L40.8 Other psoriasis
0.000 0.354 0.646
K90.9 Intestinal malabsorption, unspecified
0.000 0.435 0.565
K90.8 Other intestinal malabsorption
0.000 0.486 0.514
E03 Other hypothyroidism
0.426 0.499 0.075
E16.2 Hypoglycaemia, unspecified
0.000 0.524 0.476
K90.3 Pancreatic steatorrhoea
0.000 0.531 0.468
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.531 0.468
K90.1 Tropical sprue
0.000 0.531 0.468
E10.3 With ophthalmic complications
0.000 0.544 0.456
E10 Insulin-dependent diabetes mellitus
0.000 0.545 0.455
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.556 0.444
E16 Other disorders of pancreatic internal secretion
0.000 0.560 0.440
E10.1 With ketoacidosis
0.000 0.569 0.431
G93 Other disorders of brain
0.403 0.597 0.000
G90-G99 Other disorders of the nervous system
0.403 0.597 0.000
G91 Hydrocephalus
0.402 0.598 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.599 0.401
E10-E14 Diabetes mellitus
0.000 0.603 0.397
G93.2 Benign intracranial hypertension
0.394 0.606 0.000
G91.9 Hydrocephalus, unspecified
0.392 0.608 0.000
E10.2 With renal complications
0.000 0.612 0.388
G90 Disorders of autonomic nervous system
0.381 0.619 0.000
G93.8 Other specified disorders of brain
0.378 0.622 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.626 0.374
G91.1 Obstructive hydrocephalus
0.366 0.634 0.000
G93.0 Cerebral cysts
0.363 0.636 0.000
E10.0 With coma
0.000 0.639 0.361
E03.5 Myxoedema coma
0.305 0.640 0.054
E03.4 Atrophy of thyroid (acquired)
0.305 0.640 0.054
E03.3 Postinfectious hypothyroidism
0.305 0.640 0.054
E03.1 Congenital hypothyroidism without goitre
0.305 0.640 0.054
E03.0 Congenital hypothyroidism with diffuse goitre
0.305 0.640 0.054
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.305 0.646 0.049
G90.3 Multisystem degeneration
0.347 0.653 0.000
E10.6 With other specified complications
0.000 0.655 0.345
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.659 0.341
G95 Other diseases of spinal cord
0.339 0.661 0.000
E10.9 Without complications
0.000 0.662 0.338
E10.5 With peripheral circulatory complications
0.000 0.662 0.337
E16.1 Other hypoglycaemia
0.000 0.665 0.335
D86.9 Sarcoidosis, unspecified
0.000 0.665 0.335
G94 Other disorders of brain in diseases classified elsewhere
0.330 0.670 0.000
D86 Sarcoidosis
0.000 0.671 0.329
E10.7 With multiple complications
0.000 0.674 0.326
E13 Other specified diabetes mellitus
0.000 0.683 0.317
E10.4 With neurological complications
0.000 0.683 0.317
E10.8 With unspecified complications
0.000 0.684 0.316
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.684 0.315
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.684 0.315
E16.4 Abnormal secretion of gastrin
0.000 0.684 0.315
E16.3 Increased secretion of glucagon
0.000 0.684 0.315
G93.5 Compression of brain
0.315 0.685 0.000
G91.2 Normal-pressure hydrocephalus
0.315 0.685 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.315 0.685 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.314 0.686 0.000
E00-E07 Disorders of thyroid gland
0.132 0.690 0.177
G91.8 Other hydrocephalus
0.308 0.692 0.000
E03.8 Other specified hypothyroidism
0.253 0.693 0.054
G95.0 Syringomyelia and syringobulbia
0.304 0.696 0.000
D86.0 Sarcoidosis of lung
0.000 0.699 0.301
G93.6 Cerebral oedema
0.296 0.704 0.000
D86.8 Sarcoidosis of other and combined sites
0.000 0.704 0.296
G98 Other disorders of nervous system, not elsewhere classified
0.293 0.707 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.293 0.707 0.000
E83.1 Disorders of iron metabolism
0.000 0.708 0.292
G93.7 Reye's syndrome
0.289 0.711 0.000
G92 Toxic encephalopathy
0.289 0.711 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.289 0.711 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.712 0.288
D86.1 Sarcoidosis of lymph nodes
0.000 0.715 0.285
E12 Malnutrition-related diabetes mellitus
0.000 0.715 0.285
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.279 0.721 0.000
G95.8 Other specified diseases of spinal cord
0.277 0.723 0.000
G96 Other disorders of central nervous system
0.276 0.724 0.000
E70-E90 Metabolic disorders
0.000 0.724 0.276
G95.9 Disease of spinal cord, unspecified
0.276 0.724 0.000
E83 Disorders of mineral metabolism
0.000 0.727 0.273
G90.8 Other disorders of autonomic nervous system
0.273 0.727 0.000
G90.4 Autonomic dysreflexia
0.273 0.727 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.273 0.727 0.000
E13.9 Without complications
0.000 0.731 0.269
G91.0 Communicating hydrocephalus
0.269 0.731 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.266 0.734 0.000
E88 Other metabolic disorders
0.000 0.741 0.259
G94.1 Hydrocephalus in neoplastic disease
0.253 0.747 0.000
G90.2 Horner's syndrome
0.247 0.753 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.753 0.247
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.753 0.247
G93.3 Postviral fatigue syndrome
0.244 0.756 0.000
E85 Amyloidosis
0.000 0.757 0.243
D86.3 Sarcoidosis of skin
0.000 0.762 0.238
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.236 0.763 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.236 0.763 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.764 0.236
E11.4 With neurological complications
0.000 0.768 0.232
L40-L45 Papulosquamous disorders
0.000 0.769 0.231
E13.8 With unspecified complications
0.000 0.772 0.228
E13.7 With multiple complications
0.000 0.772 0.228
E13.6 With other specified complications
0.000 0.772 0.228
E13.5 With peripheral circulatory complications
0.000 0.772 0.228
E13.4 With neurological complications
0.000 0.772 0.228
E13.2 With renal complications
0.000 0.772 0.228
E13.1 With ketoacidosis
0.000 0.772 0.228
E13.0 With coma
0.000 0.772 0.228
G93.9 Disorder of brain, unspecified
0.223 0.777 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.095 0.778 0.127
E00 Congenital iodine-deficiency syndrome
0.095 0.778 0.127
D80-D89 Certain disorders involving the immune mechanism
0.000 0.780 0.220
G96.0 Cerebrospinal fluid leak
0.219 0.780 0.000
E50-E64 Other nutritional deficiencies
0.000 0.783 0.217
E02 Subclinical iodine-deficiency hypothyroidism
0.094 0.784 0.122
E07 Other disorders of thyroid
0.126 0.785 0.089
G97.0 Cerebrospinal fluid leak from spinal puncture
0.215 0.785 0.000
G97.8 Other postprocedural disorders of nervous system
0.212 0.788 0.000
E13.3 With ophthalmic complications
0.000 0.789 0.211
E40-E46 Malnutrition
0.000 0.791 0.209
E83.5 Disorders of calcium metabolism
0.000 0.792 0.208
E88.2 Lipomatosis, not elsewhere classified
0.000 0.795 0.205
E12.9 Without complications
0.000 0.795 0.204
E12.8 With unspecified complications
0.000 0.795 0.204
E12.7 With multiple complications
0.000 0.795 0.204
E12.6 With other specified complications
0.000 0.795 0.204
E12.5 With peripheral circulatory complications
0.000 0.795 0.204
E12.4 With neurological complications
0.000 0.795 0.204
E12.3 With ophthalmic complications
0.000 0.795 0.204
E12.2 With renal complications
0.000 0.795 0.204
E12.1 With ketoacidosis
0.000 0.795 0.204
E12.0 With coma
0.000 0.795 0.204
G96.8 Other specified disorders of central nervous system
0.204 0.796 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.200 0.799 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.200 0.799 0.000
E85.3 Secondary systemic amyloidosis
0.000 0.801 0.199
G96.9 Disorder of central nervous system, unspecified
0.198 0.802 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.802 0.198
E77 Disorders of glycoprotein metabolism
0.000 0.802 0.198
E76 Disorders of glycosaminoglycan metabolism
0.000 0.802 0.198
E72 Other disorders of amino-acid metabolism
0.000 0.802 0.198
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.802 0.198
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.802 0.198
E11.8 With unspecified complications
0.000 0.803 0.197
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.804 0.196
E83.8 Other disorders of mineral metabolism
0.000 0.804 0.196
E83.2 Disorders of zinc metabolism
0.000 0.804 0.196
E83.0 Disorders of copper metabolism
0.000 0.804 0.196
E14 Unspecified diabetes mellitus
0.000 0.806 0.194
G95.1 Vascular myelopathies
0.193 0.807 0.000
E85.4 Organ-limited amyloidosis
0.000 0.807 0.193
E84 Cystic fibrosis
0.000 0.808 0.192
E85.9 Amyloidosis, unspecified
0.000 0.808 0.192
E70 Disorders of aromatic amino-acid metabolism
0.000 0.809 0.191
E55 Vitamin D deficiency
0.000 0.809 0.190
E11.1 With ketoacidosis
0.000 0.811 0.189
E06 Thyroiditis
0.090 0.812 0.098
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.812 0.187
E88.9 Metabolic disorder, unspecified
0.000 0.814 0.185
E11.6 With other specified complications
0.000 0.815 0.185
E11.5 With peripheral circulatory complications
0.000 0.815 0.185
E05 Thyrotoxicosis [hyperthyroidism]
0.015 0.816 0.168
E20-E35 Disorders of other endocrine glands
0.000 0.819 0.181
E73 Lactose intolerance
0.000 0.819 0.181
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.821 0.179
E74 Other disorders of carbohydrate metabolism
0.000 0.821 0.179
E11.7 With multiple complications
0.000 0.823 0.177
E65-E68 Obesity and other hyperalimentation
0.000 0.823 0.177
E88.3 Tumour lysis syndrome
0.000 0.823 0.177
E85.8 Other amyloidosis
0.000 0.826 0.174
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.826 0.174
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.826 0.174
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.826 0.174
E55.9 Vitamin D deficiency, unspecified
0.000 0.828 0.172
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.829 0.170
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.831 0.168
E11.2 With renal complications
0.000 0.831 0.169
L44 Other papulosquamous disorders
0.000 0.834 0.166
L41 Parapsoriasis
0.000 0.834 0.166
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.834 0.166
E88.8 Other specified metabolic disorders
0.000 0.836 0.163
D80 Immunodeficiency with predominantly antibody defects
0.000 0.837 0.163
L42 Pityriasis rosea
0.000 0.838 0.162
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.839 0.161
G93.4 Encephalopathy, unspecified
0.159 0.840 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.068 0.840 0.091
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.068 0.840 0.091
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.068 0.840 0.091
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.068 0.840 0.091
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.068 0.840 0.091
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.068 0.840 0.091
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.068 0.840 0.091
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.068 0.840 0.091
D81 Combined immunodeficiencies
0.000 0.842 0.158
D82 Immunodeficiency associated with other major defects
0.000 0.842 0.158
D50-D53 Nutritional anaemias
0.000 0.843 0.157
D51 Vitamin B12 deficiency anaemia
0.000 0.843 0.157
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.844 0.155
E63 Other nutritional deficiencies
0.000 0.844 0.155
E51 Thiamine deficiency
0.000 0.844 0.155
E50 Vitamin A deficiency
0.000 0.844 0.155
E60 Dietary zinc deficiency
0.000 0.844 0.155
E59 Dietary selenium deficiency
0.000 0.844 0.155
E54 Ascorbic acid deficiency
0.000 0.844 0.155
E52 Niacin deficiency [pellagra]
0.000 0.844 0.155
E07.1 Dyshormogenetic goitre
0.090 0.846 0.064
E07.0 Hypersecretion of calcitonin
0.090 0.846 0.064
G97.1 Other reaction to spinal and lumbar puncture
0.153 0.846 0.000
E14.4 With neurological complications
0.000 0.847 0.153
D83 Common variable immunodeficiency
0.000 0.847 0.153
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.850 0.150
E45 Retarded development following protein-energy malnutrition
0.000 0.850 0.150
E43 Unspecified severe protein-energy malnutrition
0.000 0.850 0.150
E42 Marasmic kwashiorkor
0.000 0.850 0.150
E41 Nutritional marasmus
0.000 0.850 0.150
E40 Kwashiorkor
0.000 0.850 0.150
E14.1 With ketoacidosis
0.000 0.850 0.150
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.851 0.149
G95.2 Cord compression, unspecified
0.149 0.851 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.851 0.149
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.854 0.146
E58 Dietary calcium deficiency
0.000 0.854 0.145
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.855 0.145
G35 Multiple sclerosis
0.000 0.856 0.144
G96.1 Disorders of meninges, not elsewhere classified
0.142 0.857 0.000
E71.3 Disorders of fatty-acid metabolism
0.000 0.857 0.142
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.857 0.142
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.857 0.142
E71.0 Maple-syrup-urine disease
0.000 0.857 0.142
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.857 0.142
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.857 0.142
E72.5 Disorders of glycine metabolism
0.000 0.857 0.142
E72.4 Disorders of ornithine metabolism
0.000 0.857 0.142
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.857 0.142
E72.2 Disorders of urea cycle metabolism
0.000 0.857 0.142
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.857 0.142
E72.0 Disorders of amino-acid transport
0.000 0.857 0.142
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.857 0.142
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.857 0.142
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.857 0.142
E76.2 Other mucopolysaccharidoses
0.000 0.857 0.142
E76.1 Mucopolysaccharidosis, type II
0.000 0.857 0.142
E76.0 Mucopolysaccharidosis, type I
0.000 0.857 0.142
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.857 0.142
E77.8 Other disorders of glycoprotein metabolism
0.000 0.857 0.142
E77.1 Defects in glycoprotein degradation
0.000 0.857 0.142
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.857 0.142
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.857 0.142
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.857 0.142
E79.1 Lesch-Nyhan syndrome
0.000 0.857 0.142
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.857 0.142
E27 Other disorders of adrenal gland
0.000 0.857 0.142
E14.8 With unspecified complications
0.000 0.858 0.142
E20 Hypoparathyroidism
0.000 0.858 0.142
E56 Other vitamin deficiencies
0.000 0.859 0.141
E29 Testicular dysfunction
0.000 0.860 0.140
E14.7 With multiple complications
0.000 0.860 0.139
E14.2 Withrenal complications
0.000 0.860 0.139
E14.0 With coma
0.000 0.860 0.139
E07.8 Other specified disorders of thyroid
0.070 0.861 0.069
E86 Volume depletion
0.000 0.861 0.139
E84.8 Cystic fibrosis with other manifestations
0.000 0.862 0.138
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.862 0.138
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.862 0.138
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.863 0.137
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.863 0.137
E70.2 Disorders of tyrosine metabolism
0.000 0.863 0.137
E70.1 Other hyperphenylalaninaemias
0.000 0.863 0.137
E70.0 Classical phenylketonuria
0.000 0.863 0.137
E55.0 Rickets, active
0.000 0.863 0.137
D72 Other disorders of white blood cells
0.000 0.865 0.135
E06.4 Drug-induced thyroiditis
0.064 0.865 0.070
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.064 0.865 0.070
E06.0 Acute thyroiditis
0.064 0.865 0.070
E14.6 With other specified complications
0.000 0.865 0.135
E34 Other endocrine disorders
0.000 0.866 0.134
E05.8 Other thyrotoxicosis
0.010 0.867 0.123
E27.1 Primary adrenocortical insufficiency
0.000 0.867 0.133
E06.1 Subacute thyroiditis
0.067 0.867 0.065
E07.9 Disorder of thyroid, unspecified
0.125 0.867 0.008
E05.5 Thyroid crisis or storm
0.011 0.868 0.121
E05.4 Thyrotoxicosis factitia
0.011 0.868 0.121
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.011 0.868 0.121
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.011 0.868 0.121
E23.6 Other disorders of pituitary gland
0.000 0.868 0.132
E84.9 Cystic fibrosis, unspecified
0.000 0.869 0.131
D72.8 Other specified disorders of white blood cells
0.000 0.869 0.131
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.869 0.130
D53 Other nutritional anaemias
0.000 0.870 0.130
E06.5 Other chronic thyroiditis
0.073 0.870 0.057
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.870 0.130
E32 Diseases of thymus
0.000 0.870 0.130
E31 Polyglandular dysfunction
0.000 0.870 0.130
E30 Disorders of puberty, not elsewhere classified
0.000 0.870 0.130
E25 Adrenogenital disorders
0.000 0.870 0.130
E73.8 Other lactose intolerance
0.000 0.870 0.130
E73.1 Secondary lactase deficiency
0.000 0.870 0.130
E73.0 Congenital lactase deficiency
0.000 0.870 0.130
E70.3 Albinism
0.000 0.870 0.130
D75 Other diseases of blood and blood-forming organs
0.000 0.870 0.130
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.009 0.871 0.120
E75.6 Lipid storage disorder, unspecified
0.000 0.871 0.128
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.871 0.128
E75.3 Sphingolipidosis, unspecified
0.000 0.871 0.128
E75.2 Other sphingolipidosis
0.000 0.871 0.128
E75.1 Other gangliosidosis
0.000 0.871 0.128
E75.0 GM2 gangliosidosis
0.000 0.871 0.128
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.871 0.128
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.871 0.128
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.871 0.128
E74.2 Disorders of galactose metabolism
0.000 0.871 0.128
E74.1 Disorders of fructose metabolism
0.000 0.871 0.128
E74.0 Glycogen storage disease
0.000 0.871 0.128
E67 Other hyperalimentation
0.000 0.873 0.127
E68 Sequelae of hyperalimentation
0.000 0.873 0.127
E14.5 With peripheral circulatory complications
0.000 0.874 0.126
D89.1 Cryoglobulinaemia
0.000 0.874 0.126
E06.9 Thyroiditis, unspecified
0.043 0.875 0.082
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.875 0.125
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.875 0.125
E24 Cushing's syndrome
0.000 0.876 0.124
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.877 0.123
E14.3 With ophthalmic complications
0.000 0.877 0.123
E53 Deficiency of other B group vitamins
0.000 0.877 0.123
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.877 0.123
E22 Hyperfunction of pituitary gland
0.000 0.877 0.123
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.878 0.122
D89.3 Immune reconstitution syndrome
0.000 0.878 0.122
G99 Other disorders of nervous system in diseases classified elsewhere
0.122 0.878 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.879 0.121
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.879 0.120
L41.9 Parapsoriasis, unspecified
0.000 0.881 0.119
L41.8 Other parapsoriasis
0.000 0.881 0.119
L41.5 Retiform parapsoriasis
0.000 0.881 0.119
L41.4 Large plaque parapsoriasis
0.000 0.881 0.119
L41.3 Small plaque parapsoriasis
0.000 0.881 0.119
L41.2 Lymphomatoid papulosis
0.000 0.881 0.119
L41.1 Pityriasis lichenoides chronica
0.000 0.881 0.119
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.881 0.119
L44.9 Papulosquamous disorder, unspecified
0.000 0.881 0.119
L44.8 Other specified papulosquamous disorders
0.000 0.881 0.119
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.881 0.119
L44.3 Lichen ruber moniliformis
0.000 0.881 0.119
L44.2 Lichen striatus
0.000 0.881 0.119
L44.1 Lichen nitidus
0.000 0.881 0.119
L44.0 Pityriasis rubra pilaris
0.000 0.881 0.119
D84 Other immunodeficiencies
0.001 0.882 0.117
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.883 0.117
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.883 0.117
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.883 0.117
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.883 0.117
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.883 0.117
E11.0 With coma
0.000 0.884 0.115
E87.7 Fluid overload
0.000 0.885 0.115
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.885 0.115
E87.5 Hyperkalaemia
0.000 0.885 0.115
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.886 0.114
E23.0 Hypopituitarism
0.000 0.886 0.114
E20.9 Hypoparathyroidism, unspecified
0.000 0.886 0.114
D81.9 Combined immunodeficiency, unspecified
0.000 0.886 0.113
D81.8 Other combined immunodeficiencies
0.000 0.886 0.113
D81.7 Major histocompatibility complex class II deficiency
0.000 0.886 0.113
D81.6 Major histocompatibility complex class I deficiency
0.000 0.886 0.113
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.886 0.113
D81.4 Nezelof's syndrome
0.000 0.886 0.113
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.886 0.113
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.886 0.113
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.886 0.113
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.886 0.113
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.886 0.113
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.886 0.113
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.886 0.113
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.886 0.113
D82.2 Immunodeficiency with short-limbed stature
0.000 0.886 0.113
D82.0 Wiskott-Aldrich syndrome
0.000 0.886 0.113
D82.1 Di George's syndrome
0.000 0.886 0.113
E11.3 With ophthalmic complications
0.000 0.887 0.113
E73.9 Lactose intolerance, unspecified
0.000 0.887 0.113
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.888 0.112
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.888 0.112
D51.2 Transcobalamin II deficiency
0.000 0.888 0.112
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.888 0.112
E50.9 Vitamin A deficiency, unspecified
0.000 0.888 0.112
E50.8 Other manifestations of vitamin A deficiency
0.000 0.888 0.112
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.888 0.112
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.888 0.112
E50.5 Vitamin A deficiency with night blindness
0.000 0.888 0.112
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.888 0.112
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.888 0.112
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.888 0.112
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.888 0.112
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.888 0.112
E51.9 Thiamine deficiency, unspecified
0.000 0.888 0.112
E51.8 Other manifestations of thiamine deficiency
0.000 0.888 0.112
E51.2 Wernicke's encephalopathy
0.000 0.888 0.112
E51.1 Beriberi
0.000 0.888 0.112
E63.9 Nutritional deficiency, unspecified
0.000 0.888 0.112
E63.8 Other specified nutritional deficiencies
0.000 0.888 0.112
E63.1 Imbalance of constituents of food intake
0.000 0.888 0.112
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.888 0.112
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.888 0.112
E64.8 Sequelae of other nutritional deficiencies
0.000 0.888 0.112
E64.3 Sequelae of rickets
0.000 0.888 0.112
E64.2 Sequelae of vitamin C deficiency
0.000 0.888 0.112
E64.1 Sequelae of vitamin A deficiency
0.000 0.888 0.112
E64.0 Sequelae of protein-energy malnutrition
0.000 0.888 0.112
D53.9 Nutritional anaemia, unspecified
0.000 0.889 0.111
E29.1 Testicular hypofunction
0.000 0.889 0.111
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.889 0.111
E34.0 Carcinoid syndrome
0.000 0.889 0.110
E65 Localised adiposity
0.000 0.890 0.110
E23.7 Disorder of pituitary gland, unspecified
0.000 0.890 0.110
D83.8 Other common variable immunodeficiencies
0.000 0.890 0.110
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.890 0.110
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.890 0.110
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.890 0.110
M45.X9 Ankylosing spondylitis (Site unspecified)
0.110 0.890 0.000
E75.5 Other lipid storage disorders
0.000 0.890 0.109
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.891 0.109
E44.1 Mild protein-energy malnutrition
0.000 0.892 0.108
E44.0 Moderate protein-energy malnutrition
0.000 0.892 0.108
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.892 0.107
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.893 0.107
E23.1 Drug-induced hypopituitarism
0.000 0.893 0.107
D74 Methaemoglobinaemia
0.000 0.895 0.105
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.895 0.105
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.895 0.105
D83.9 Common variable immunodeficiency, unspecified
0.000 0.895 0.105
E22.1 Hyperprolactinaemia
0.000 0.895 0.105
D70 Agranulocytosis
0.000 0.895 0.105
D55-D59 Haemolytic anaemias
0.000 0.895 0.105
C90.0 Multiple myeloma
0.000 0.896 0.104
D75.0 Familial erythrocytosis
0.000 0.896 0.104
E06.3 Autoimmune thyroiditis
0.061 0.896 0.043
E27.5 Adrenomedullary hyperfunction
0.000 0.898 0.102
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.898 0.102
E27.0 Other adrenocortical overactivity
0.000 0.898 0.102
E34.9 Endocrine disorder, unspecified
0.000 0.898 0.102
E20.8 Other hypoparathyroidism
0.000 0.898 0.102
E20.1 Pseudohypoparathyroidism
0.000 0.898 0.102
E20.0 Idiopathic hypoparathyroidism
0.000 0.898 0.102
L43 Lichen planus
0.000 0.898 0.102
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.898 0.102
E56.9 Vitamin deficiency, unspecified
0.000 0.898 0.101
E56.8 Deficiency of other vitamins
0.000 0.898 0.101
E56.0 Deficiency of vitamin E
0.000 0.898 0.101
E29.9 Testicular dysfunction, unspecified
0.000 0.899 0.101
E29.8 Other testicular dysfunction
0.000 0.899 0.101
E29.0 Testicular hyperfunction
0.000 0.899 0.101
D75.1 Secondary polycythaemia
0.000 0.899 0.101
D75.2 Essential thrombocytosis
0.000 0.899 0.101
E61 Deficiency of other nutrient elements
0.000 0.902 0.097
D72.9 Disorder of white blood cells, unspecified
0.000 0.903 0.097
D72.0 Genetic anomalies of leukocytes
0.000 0.903 0.097
D50 Iron deficiency anaemia
0.000 0.903 0.097
E34.5 Androgen resistance syndrome
0.000 0.903 0.096
E34.4 Constitutional tall stature
0.000 0.903 0.096
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.903 0.096
E34.1 Other hypersecretion of intestinal hormones
0.000 0.903 0.096
E26 Hyperaldosteronism
0.000 0.904 0.096
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.904 0.096
E27.8 Other specified disorders of adrenal gland
0.000 0.905 0.095
D53.8 Other specified nutritional anaemias
0.000 0.906 0.094
D53.2 Scorbutic anaemia
0.000 0.906 0.094
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.906 0.094
D53.0 Protein deficiency anaemia
0.000 0.906 0.094
E25.9 Adrenogenital disorder, unspecified
0.000 0.906 0.093
E25.8 Other adrenogenital disorders
0.000 0.906 0.093
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.906 0.093
E30.9 Disorder of puberty, unspecified
0.000 0.906 0.093
E30.8 Other disorders of puberty
0.000 0.906 0.093
E30.1 Precocious puberty
0.000 0.906 0.093
E30.0 Delayed puberty
0.000 0.906 0.093
E31.9 Polyglandular dysfunction, unspecified
0.000 0.906 0.093
E31.8 Other polyglandular dysfunction
0.000 0.906 0.093
E31.1 Polyglandular hyperfunction
0.000 0.906 0.093
E31.0 Autoimmune polyglandular failure
0.000 0.906 0.093
E32.9 Disease of thymus, unspecified
0.000 0.906 0.093
E32.8 Other diseases of thymus
0.000 0.906 0.093
E32.1 Abscess of thymus
0.000 0.906 0.093
E32.0 Persistent hyperplasia of thymus
0.000 0.906 0.093
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.906 0.093
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.906 0.093
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.906 0.093
D50.8 Other iron deficiency anaemias
0.000 0.907 0.093
E27.9 Disorder of adrenal gland, unspecified
0.000 0.908 0.091
E67.8 Other specified hyperalimentation
0.000 0.909 0.091
E67.3 Hypervitaminosis D
0.000 0.909 0.091
E67.2 Megavitamin-B6 syndrome
0.000 0.909 0.091
E67.1 Hypercarotenaemia
0.000 0.909 0.091
E67.0 Hypervitaminosis A
0.000 0.909 0.091
E46 Unspecified protein-energy malnutrition
0.001 0.909 0.091

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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