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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4713447
log Bayes Factor = 61.9699
Chromosome 6   position 31,162,963  (GRCh37) Explore rs4713447 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
D80-D89 Certain disorders involving the immune mechanism
0.000 0.001 0.999
R31 Unspecified haematuria
0.998 0.002 0.000
D86 Sarcoidosis
0.000 0.003 0.997
D60-D64 Aplastic and other anaemias
0.000 0.003 0.997
D64 Other anaemias
0.000 0.005 0.995
D64.9 Anaemia, unspecified
0.000 0.007 0.993
D86.9 Sarcoidosis, unspecified
0.000 0.008 0.992
L40 Psoriasis
0.000 0.009 0.991
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.020 0.980
L40.5 Arthropathic psoriasis
0.000 0.022 0.978
D69 Purpura and other haemorrhagic conditions
0.000 0.025 0.975
D69.6 Thrombocytopenia, unspecified
0.000 0.029 0.971
D50-D53 Nutritional anaemias
0.000 0.046 0.954
D86.3 Sarcoidosis of skin
0.000 0.073 0.927
D80 Immunodeficiency with predominantly antibody defects
0.000 0.098 0.902
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.104 0.896
L40.0 Psoriasis vulgaris
0.000 0.114 0.886
D50 Iron deficiency anaemia
0.000 0.119 0.881
D50.9 Iron deficiency anaemia, unspecified
0.000 0.128 0.872
E03 Other hypothyroidism
0.000 0.135 0.865
D66 Hereditary factor VIII deficiency
0.000 0.136 0.864
D70 Agranulocytosis
0.000 0.137 0.863
D62 Acute posthaemorrhagic anaemia
0.000 0.155 0.845
D69.2 Other nonthrombocytopenic purpura
0.000 0.164 0.836
D61 Other aplastic anaemias
0.000 0.168 0.832
D64.8 Other specified anaemias
0.000 0.179 0.820
D69.5 Secondary thrombocytopenia
0.000 0.182 0.818
D69.4 Other primary thrombocytopenia
0.000 0.183 0.817
D51 Vitamin B12 deficiency anaemia
0.000 0.185 0.815
L40.1 Generalised pustular psoriasis
0.000 0.193 0.807
D55-D59 Haemolytic anaemias
0.000 0.196 0.804
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.198 0.802
D52 Folate deficiency anaemia
0.000 0.214 0.786
D86.0 Sarcoidosis of lung
0.000 0.222 0.778
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.225 0.775
D72 Other disorders of white blood cells
0.000 0.225 0.775
D84 Other immunodeficiencies
0.000 0.229 0.771
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.236 0.764
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.242 0.758
L40.8 Other psoriasis
0.000 0.260 0.740
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.738
E00-E07 Disorders of thyroid gland
0.000 0.262 0.738
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.266 0.734
D83 Common variable immunodeficiency
0.000 0.267 0.733
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.271 0.729
D61.9 Aplastic anaemia, unspecified
0.000 0.274 0.726
L40.4 Guttate psoriasis
0.000 0.278 0.722
E05.9 Thyrotoxicosis, unspecified
0.000 0.282 0.718
D81 Combined immunodeficiencies
0.000 0.284 0.716
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.285 0.715
D64.4 Congenital dyserythropoietic anaemia
0.000 0.287 0.713
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.287 0.713
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.287 0.713
D64.0 Hereditary sideroblastic anaemia
0.000 0.287 0.713
L40.2 Acrodermatitis continua
0.000 0.290 0.710
D64.3 Other sideroblastic anaemias
0.000 0.292 0.708
D86.1 Sarcoidosis of lymph nodes
0.000 0.297 0.703
D69.8 Other specified haemorrhagic conditions
0.000 0.301 0.699
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.325 0.675
E03.8 Other specified hypothyroidism
0.000 0.328 0.672
D58 Other hereditary haemolytic anaemias
0.000 0.330 0.670
D52.9 Folate deficiency anaemia, unspecified
0.000 0.335 0.665
D59 Acquired haemolytic anaemia
0.000 0.348 0.652
D67 Hereditary factor IX deficiency
0.000 0.348 0.652
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.350 0.650
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.354 0.646
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.354 0.646
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.354 0.646
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.354 0.646
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.354 0.646
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.354 0.646
D74 Methaemoglobinaemia
0.000 0.357 0.643
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.357 0.643
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.357 0.643
D69.1 Qualitative platelet defects
0.000 0.358 0.642
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.359 0.641
D72.1 Eosinophilia
0.000 0.363 0.637
D72.8 Other specified disorders of white blood cells
0.000 0.364 0.636
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.368 0.632
D50.1 Sideropenic dysphagia
0.000 0.368 0.632
D82 Immunodeficiency associated with other major defects
0.000 0.371 0.629
D84.9 Immunodeficiency, unspecified
0.000 0.373 0.627
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.380 0.620
E03.5 Myxoedema coma
0.000 0.380 0.620
E03.4 Atrophy of thyroid (acquired)
0.000 0.380 0.620
E03.3 Postinfectious hypothyroidism
0.000 0.380 0.620
D61.0 Constitutional aplastic anaemia
0.000 0.383 0.617
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.383 0.617
D58.0 Hereditary spherocytosis
0.000 0.388 0.612
E03.1 Congenital hypothyroidism without goitre
0.000 0.390 0.609
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.394 0.606
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.394 0.606
D84.1 Defects in the complement system
0.000 0.399 0.601
D61.8 Other specified aplastic anaemias
0.000 0.403 0.597
D61.3 Idiopathic aplastic anaemia
0.000 0.403 0.597
D61.2 Aplastic anaemia due to other external agents
0.000 0.403 0.597
D76.3 Other histiocytosis syndromes
0.000 0.414 0.586
D51.2 Transcobalamin II deficiency
0.000 0.415 0.584
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.415 0.584
D53 Other nutritional anaemias
0.000 0.417 0.583
D57 Sickle-cell disorders
0.000 0.424 0.576
D55 Anaemia due to enzyme disorders
0.000 0.424 0.576
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.427 0.572
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.432 0.568
D52.8 Other folate deficiency anaemias
0.000 0.437 0.563
D52.1 Drug-induced folate deficiency anaemia
0.000 0.437 0.563
D52.0 Dietary folate deficiency anaemia
0.000 0.437 0.563
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.437 0.563
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.444 0.556
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.444 0.556
D89.3 Immune reconstitution syndrome
0.000 0.444 0.556
D72.9 Disorder of white blood cells, unspecified
0.000 0.444 0.556
D72.0 Genetic anomalies of leukocytes
0.000 0.444 0.556
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.447 0.553
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.449 0.551
D86.8 Sarcoidosis of other and combined sites
0.000 0.450 0.549
D61.1 Drug-induced aplastic anaemia
0.000 0.453 0.547
D83.9 Common variable immunodeficiency, unspecified
0.000 0.457 0.543
D59.1 Other autoimmune haemolytic anaemias
0.000 0.458 0.542
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.459 0.541
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.469 0.531
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.471 0.529
E00 Congenital iodine-deficiency syndrome
0.000 0.471 0.529
D69.0 Allergic purpura
0.000 0.474 0.526
D83.8 Other common variable immunodeficiencies
0.000 0.474 0.526
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.474 0.526
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.474 0.526
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.474 0.526
E05.5 Thyroid crisis or storm
0.000 0.477 0.523
E05.4 Thyrotoxicosis factitia
0.000 0.477 0.523
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.477 0.523
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.477 0.523
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.481 0.519
D81.9 Combined immunodeficiency, unspecified
0.000 0.486 0.513
D81.8 Other combined immunodeficiencies
0.000 0.486 0.513
D81.7 Major histocompatibility complex class II deficiency
0.000 0.486 0.513
D81.6 Major histocompatibility complex class I deficiency
0.000 0.486 0.513
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.486 0.513
D81.4 Nezelof's syndrome
0.000 0.486 0.513
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.486 0.513
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.486 0.513
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.486 0.513
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.486 0.513
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.487 0.513
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.487 0.513
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.487 0.513
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.495 0.504
D60.8 Other acquired pure red cell aplasias
0.000 0.516 0.484
D60.1 Transient acquired pure red cell aplasia
0.000 0.516 0.484
D60.0 Chronic acquired pure red cell aplasia
0.000 0.516 0.484
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.519 0.480
D58.1 Hereditary elliptocytosis
0.000 0.519 0.480
D69.9 Haemorrhagic condition, unspecified
0.000 0.522 0.478
K90 Intestinal malabsorption
0.000 0.529 0.471
D59.8 Other acquired haemolytic anaemias
0.000 0.532 0.468
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.532 0.468
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.532 0.468
D59.3 Haemolytic-uraemic syndrome
0.000 0.532 0.468
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.532 0.468
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.532 0.468
D89.1 Cryoglobulinaemia
0.000 0.536 0.463
D74.9 Methaemoglobinaemia, unspecified
0.000 0.539 0.461
D74.8 Other methaemoglobinaemias
0.000 0.539 0.461
D74.0 Congenital methaemoglobinaemia
0.000 0.539 0.461
E07 Other disorders of thyroid
0.000 0.545 0.455
D84.8 Other specified immunodeficiencies
0.000 0.547 0.452
D58.2 Other haemoglobinopathies
0.000 0.548 0.452
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.549 0.451
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.549 0.451
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.549 0.451
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.549 0.451
D82.2 Immunodeficiency with short-limbed stature
0.000 0.549 0.451
D82.0 Wiskott-Aldrich syndrome
0.000 0.549 0.451
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.555 0.445
D56 Thalassaemia
0.000 0.556 0.444
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.574 0.425
E04 Other non-toxic goitre
0.000 0.580 0.420
D53.8 Other specified nutritional anaemias
0.000 0.582 0.418
D53.2 Scorbutic anaemia
0.000 0.582 0.418
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.582 0.418
D53.0 Protein deficiency anaemia
0.000 0.582 0.418
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.587 0.413
D55.8 Other anaemias due to enzyme disorders
0.000 0.587 0.413
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.587 0.413
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.587 0.413
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.587 0.413
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.587 0.413
D57.8 Other sickle-cell disorders
0.000 0.587 0.413
D57.3 Sickle-cell trait
0.000 0.587 0.413
D57.2 Double heterozygous sickling disorders
0.000 0.587 0.413
D57.1 Sickle-cell anaemia without crisis
0.000 0.587 0.413
D57.0 Sickle-cell anaemia with crisis
0.000 0.587 0.413
D50.8 Other iron deficiency anaemias
0.000 0.594 0.406
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.600 0.399
K75 Other inflammatory liver diseases
0.000 0.612 0.388
E07.8 Other specified disorders of thyroid
0.000 0.616 0.384
E06 Thyroiditis
0.000 0.616 0.383
K75.4 Autoimmune hepatitis
0.000 0.617 0.383
E04.0 Non-toxic diffuse goitre
0.000 0.618 0.382
K75.8 Other specified inflammatory liver diseases
0.000 0.619 0.381
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.620 0.379
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.620 0.379
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.620 0.379
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.620 0.379
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.620 0.379
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.620 0.379
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.620 0.379
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.620 0.379
K70-K77 Diseases of liver
0.000 0.622 0.378
K73 Chronic hepatitis, not elsewhere classified
0.000 0.629 0.371
K90.9 Intestinal malabsorption, unspecified
0.000 0.633 0.367
K70 Alcoholic liver disease
0.000 0.635 0.365
D82.1 Di George's syndrome
0.001 0.636 0.363
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.642 0.358
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.645 0.355
E05.8 Other thyrotoxicosis
0.001 0.651 0.349
K90.3 Pancreatic steatorrhoea
0.000 0.662 0.338
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.662 0.338
K90.1 Tropical sprue
0.000 0.662 0.338
K73.9 Chronic hepatitis, unspecified
0.000 0.666 0.334
K70.9 Alcoholic liver disease, unspecified
0.000 0.671 0.329
K70.1 Alcoholic hepatitis
0.000 0.671 0.329
E07.1 Dyshormogenetic goitre
0.000 0.673 0.326
E07.0 Hypersecretion of calcitonin
0.000 0.673 0.326
K70.0 Alcoholic fatty liver
0.000 0.678 0.322
D56.9 Thalassaemia, unspecified
0.000 0.681 0.318
D56.8 Other thalassaemias
0.000 0.681 0.318
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.681 0.318
D56.2 Delta-beta thalassaemia
0.000 0.681 0.318
D56.0 Alpha thalassaemia
0.000 0.681 0.318
D53.9 Nutritional anaemia, unspecified
0.000 0.684 0.316
E06.3 Autoimmune thyroiditis
0.000 0.685 0.315
K72 Hepatic failure, not elsewhere classified
0.000 0.689 0.311
K75.0 Abscess of liver
0.000 0.698 0.302
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.699 0.301
E04.8 Other specified non-toxic goitre
0.000 0.699 0.301
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.703 0.297
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.712 0.287
D56.1 Beta thalassaemia
0.001 0.720 0.279
K75.2 Nonspecific reactive hepatitis
0.000 0.722 0.278
K75.1 Phlebitis of portal vein
0.000 0.722 0.278
D75 Other diseases of blood and blood-forming organs
0.000 0.722 0.277
K74 Fibrosis and cirrhosis of liver
0.000 0.723 0.277
E06.4 Drug-induced thyroiditis
0.000 0.725 0.275
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.725 0.275
E06.0 Acute thyroiditis
0.000 0.725 0.275
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.725 0.275
K74.0 Hepatic fibrosis
0.000 0.727 0.273
K77 Liver disorders in diseases classified elsewhere
0.000 0.729 0.271
E06.5 Other chronic thyroiditis
0.000 0.732 0.267
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.733 0.266
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.733 0.266
K72.0 Acute and subacute hepatic failure
0.000 0.737 0.263
K90.8 Other intestinal malabsorption
0.000 0.740 0.260
E04.2 Non-toxic multinodular goitre
0.000 0.752 0.248
D56.3 Thalassaemia trait
0.001 0.752 0.248
K72.9 Hepatic failure, unspecified
0.000 0.762 0.238
D75.0 Familial erythrocytosis
0.000 0.773 0.227
D73 Diseases of spleen
0.000 0.774 0.225
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.774 0.226
K71 Toxic liver disease
0.000 0.774 0.225
K70.4 Alcoholic hepatic failure
0.000 0.783 0.217
L40-L45 Papulosquamous disorders
0.001 0.785 0.214
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.793 0.207
K72.1 Chronic hepatic failure
0.000 0.793 0.207
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.794 0.206
G35 Multiple sclerosis
0.000 0.795 0.205
E06.9 Thyroiditis, unspecified
0.001 0.800 0.199
E04.1 Non-toxic single thyroid nodule
0.000 0.800 0.200
K74.4 Secondary biliary cirrhosis
0.000 0.801 0.199
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.801 0.199
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.805 0.194
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.805 0.194
K74.1 Hepatic sclerosis
0.000 0.822 0.178
D73.1 Hypersplenism
0.000 0.828 0.172
E06.1 Subacute thyroiditis
0.001 0.837 0.161
D73.2 Chronic congestive splenomegaly
0.000 0.838 0.162
K71.9 Toxic liver disease, unspecified
0.000 0.838 0.162
K71.8 Toxic liver disease with other disorders of liver
0.000 0.838 0.162
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.838 0.162
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.838 0.162
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.838 0.162
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.838 0.162
K71.2 Toxic liver disease with acute hepatitis
0.000 0.838 0.162
K71.0 Toxic liver disease with cholestasis
0.000 0.838 0.162
D73.9 Disease of spleen, unspecified
0.000 0.838 0.161
D73.5 Infarction of spleen
0.000 0.841 0.159
K70.3 Alcoholic cirrhosis of liver
0.000 0.844 0.156
E04.9 Non-toxic goitre, unspecified
0.000 0.844 0.156
D73.3 Abscess of spleen
0.001 0.846 0.154
L44 Other papulosquamous disorders
0.001 0.846 0.153
L41 Parapsoriasis
0.001 0.846 0.153
L45 Papulosquamous disorders in diseases classified elsewhere
0.001 0.846 0.153
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.856 0.143
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.859 0.140
D73.4 Cyst of spleen
0.001 0.864 0.135
K74.6 Other and unspecified cirrhosis of liver
0.000 0.867 0.133
M06.9 Rheumatoid arthritis, unspecified
0.131 0.869 0.000
D75.2 Essential thrombocytosis
0.000 0.872 0.128
K74.5 Biliary cirrhosis, unspecified
0.000 0.873 0.127
M06 Other rheumatoid arthritis
0.127 0.873 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.123 0.877 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.879 0.121
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.119 0.881 0.000
L42 Pityriasis rosea
0.001 0.883 0.116
M06.0 Seronegative rheumatoid arthritis
0.115 0.885 0.000
M06.3 Rheumatoid nodule
0.114 0.886 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.887 0.113
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.113 0.887 0.000
D73.8 Other diseases of spleen
0.001 0.888 0.112
L41.9 Parapsoriasis, unspecified
0.001 0.889 0.110
L41.8 Other parapsoriasis
0.001 0.889 0.110
L41.5 Retiform parapsoriasis
0.001 0.889 0.110
L41.4 Large plaque parapsoriasis
0.001 0.889 0.110
L41.3 Small plaque parapsoriasis
0.001 0.889 0.110
L41.2 Lymphomatoid papulosis
0.001 0.889 0.110
L41.1 Pityriasis lichenoides chronica
0.001 0.889 0.110
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.889 0.110
L44.9 Papulosquamous disorder, unspecified
0.001 0.889 0.110
L44.8 Other specified papulosquamous disorders
0.001 0.889 0.110
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.001 0.889 0.110
L44.3 Lichen ruber moniliformis
0.001 0.889 0.110
L44.2 Lichen striatus
0.001 0.889 0.110
L44.1 Lichen nitidus
0.001 0.889 0.110
L44.0 Pityriasis rubra pilaris
0.001 0.889 0.110
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.890 0.110
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.110 0.890 0.000
M06.34 Rheumatoid nodule (Hand)
0.109 0.891 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.107 0.893 0.000
K90-K93 Other diseases of the digestive system
0.000 0.894 0.106
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.106 0.894 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.104 0.896 0.000
G62.9 Polyneuropathy, unspecified
0.000 0.898 0.102
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.100 0.900 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.099 0.901 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.098 0.902 0.000
G62 Other polyneuropathies
0.000 0.902 0.098
Chapter VI Diseases of the nervous system
0.000 0.903 0.097
K75.9 Inflammatory liver disease, unspecified
0.001 0.903 0.097
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.906 0.094
M06.8 Other specified rheumatoid arthritis
0.094 0.906 0.000
M06.4 Inflammatory polyarthropathy
0.093 0.907 0.000
M06.2 Rheumatoid bursitis
0.091 0.909 0.000
M06.1 Adult-onset Still's disease
0.091 0.909 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.910 0.090
M05.9 Seropositive rheumatoid arthritis, unspecified
0.090 0.910 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.911 0.089
M06.04 Seronegative rheumatoid arthritis (Hand)
0.088 0.912 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.912 0.088
E27 Other disorders of adrenal gland
0.000 0.913 0.087
M05 Seropositive rheumatoid arthritis
0.087 0.913 0.000
G70-G73 Diseases of myoneural junction and muscle
0.000 0.913 0.087
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.913 0.087
M05-M14 Inflammatory polyarthropathies
0.087 0.913 0.000
G62.1 Alcoholic polyneuropathy
0.000 0.914 0.086
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.085 0.915 0.000
D68 Other coagulation defects
0.000 0.915 0.085
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.916 0.084
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.084 0.916 0.000
M06.33 Rheumatoid nodule (Forearm)
0.084 0.916 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.083 0.916 0.000
Chapter XI Diseases of the digestive system
0.000 0.917 0.083
G36 Other acute disseminated demyelination
0.000 0.917 0.083
M06.08 Seronegative rheumatoid arthritis (Other)
0.082 0.918 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.082 0.918 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.082 0.918 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.082 0.918 0.000
M06.38 Rheumatoid nodule (Other)
0.082 0.918 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.082 0.918 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.082 0.918 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.082 0.918 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.081 0.919 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.081 0.919 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.919 0.081
E20-E35 Disorders of other endocrine glands
0.000 0.919 0.081
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.079 0.921 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.921 0.079
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.922 0.078
G70 Myasthenia gravis and other myoneural disorders
0.000 0.922 0.078
# Top node
0.000 0.923 0.077
M06.32 Rheumatoid nodule (Upper arm)
0.076 0.923 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.923 0.076
E27.2 Addisonian crisis
0.000 0.925 0.075
G81 Hemiplegia
0.000 0.925 0.075
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.075 0.925 0.000
G62.0 Drug-induced polyneuropathy
0.000 0.925 0.075
G83 Other paralytic syndromes
0.000 0.926 0.074
D75.8 Other specified diseases of blood and blood-forming organs
0.001 0.927 0.073
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.072 0.927 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.072 0.928 0.000
G31.8 Other specified degenerative diseases of nervous system
0.000 0.928 0.072
G71 Primary disorders of muscles
0.000 0.928 0.072
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.072 0.928 0.000
G31.0 Circumscribed brain atrophy
0.000 0.929 0.071
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.071 0.929 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.071 0.929 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.071 0.929 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.070 0.929 0.000
G62.2 Polyneuropathy due to other toxic agents
0.000 0.929 0.070
L50-L54 Urticaria and erythema
0.000 0.930 0.070
M14 Arthropathies in other diseases classified elsewhere
0.070 0.930 0.000
G83.4 Cauda equina syndrome
0.000 0.930 0.070
G70.0 Myasthenia gravis
0.000 0.930 0.070
K74.3 Primary biliary cirrhosis
0.000 0.930 0.070
G60 Hereditary and idiopathic neuropathy
0.000 0.930 0.070
L10-L14 Bullous disorders
0.000 0.931 0.069
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.931 0.069
D68.6 Other Thrombophilia
0.000 0.931 0.069
M05.1 Rheumatoid lung disease
0.068 0.932 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.068 0.932 0.000
G64 Other disorders of peripheral nervous system
0.000 0.932 0.068
M06.88 Other specified rheumatoid arthritis (Other)
0.067 0.932 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.067 0.932 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.067 0.932 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.067 0.932 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.067 0.932 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.067 0.932 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.067 0.932 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.067 0.932 0.000
D75.1 Secondary polycythaemia
0.000 0.932 0.067
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.067 0.933 0.000
G00 Bacterial meningitis, not elsewhere classified
0.000 0.933 0.067
M06.48 Inflammatory polyarthropathy (Other)
0.067 0.933 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.067 0.933 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.067 0.933 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.067 0.933 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.067 0.933 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.067 0.933 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.067 0.933 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.067 0.933 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.067 0.933 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.933 0.067
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.933 0.067
G81.9 Hemiplegia, unspecified
0.000 0.933 0.067
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.066 0.934 0.000
E24 Cushing's syndrome
0.000 0.934 0.066
E20 Hypoparathyroidism
0.000 0.934 0.066
M06.19 Adult-onset Still's disease (Site unspecified)
0.065 0.935 0.000
M06.18 Adult-onset Still's disease (Other)
0.065 0.935 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.065 0.935 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.065 0.935 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.065 0.935 0.000
M06.14 Adult-onset Still's disease (Hand)
0.065 0.935 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.065 0.935 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.065 0.935 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.065 0.935 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.065 0.935 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.065 0.935 0.000
M06.28 Rheumatoid bursitis (Other)
0.065 0.935 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.065 0.935 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.065 0.935 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.065 0.935 0.000
M06.24 Rheumatoid bursitis (Hand)
0.065 0.935 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.065 0.935 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.065 0.935 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.065 0.935 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.065 0.935 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.935 0.065
L50 Urticaria
0.000 0.935 0.065
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.064 0.936 0.000
M08 Juvenile arthritis
0.063 0.936 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.937 0.063
E27.0 Other adrenocortical overactivity
0.000 0.937 0.063
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.063 0.937 0.000
M05.0 Felty's syndrome
0.063 0.937 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.063 0.937 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.937 0.063
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.063 0.937 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.938 0.062
M09 Juvenile arthritis in diseases classified elsewhere
0.062 0.938 0.000
M05.2 Rheumatoid vasculitis
0.062 0.938 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.938 0.062
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.939 0.061
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.940 0.060
M11 Other crystal arthropathies
0.060 0.940 0.000
E34 Other endocrine disorders
0.000 0.940 0.060
E25 Adrenogenital disorders
0.000 0.940 0.060
G36.9 Acute disseminated demyelination, unspecified
0.000 0.940 0.060
G36.8 Other specified acute disseminated demyelination
0.000 0.940 0.060
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.940 0.060
G71.1 Myotonic disorders
0.000 0.940 0.060
M14.6 Neuropathic arthropathy
0.060 0.940 0.000
G81.1 Spastic hemiplegia
0.000 0.940 0.059
D68.1 Hereditary factor XI deficiency
0.000 0.941 0.059
L43 Lichen planus
0.002 0.941 0.057
G70.9 Myoneural disorder, unspecified
0.000 0.941 0.059
L52 Erythema nodosum
0.000 0.941 0.058
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.942 0.058
E32 Diseases of thymus
0.000 0.942 0.058
E31 Polyglandular dysfunction
0.000 0.942 0.058
E30 Disorders of puberty, not elsewhere classified
0.000 0.942 0.058
M12 Other specific arthropathies
0.058 0.942 0.000
G72 Other myopathies
0.000 0.942 0.058
L13 Other bullous disorders
0.000 0.943 0.057
G00.9 Bacterial meningitis, unspecified
0.000 0.943 0.057
M05.8 Other seropositive rheumatoid arthritis
0.057 0.943 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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