TreeWAS – Variant ID: rs4713467

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	1.000	0.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001	0.000
K50-K52 Noninfective enteritis and colitis	0.996	0.004	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.995	0.005	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.993	0.007	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.993	0.007	0.000
K22 Other diseases of oesophagus	0.991	0.009	0.000
K31 Other diseases of stomach and duodenum	0.989	0.011	0.000
K51 Ulcerative colitis	0.986	0.014	0.000
K31.8 Other specified diseases of stomach and duodenum	0.984	0.016	0.000
K08 Other disorders of teeth and supporting structures	0.980	0.020	0.000
M70-M79 Other soft tissue disorders	0.979	0.021	0.000
R15 Faecal incontinence	0.976	0.024	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.975	0.025	0.000
K08.3 Retained dental root	0.975	0.025	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.968	0.032	0.000
R19 Other symptoms and signs involving the digestive system and abdomen	0.964	0.036	0.000
S60-S69 Injuries to the wrist and hand	0.961	0.039	0.000
M75 Shoulder lesions	0.960	0.040	0.000
R19.4 Change in bowel habit	0.954	0.046	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.949	0.051	0.000
R30-R39 Symptoms and signs involving the urinary system	0.947	0.053	0.000
M45-M49 Spondylopathies	0.944	0.056	0.000
Chapter I Certain infectious and parasitic diseases	0.937	0.063	0.000
K70-K77 Diseases of liver	0.936	0.064	0.000
K22.1 Ulcer of oesophagus	0.927	0.073	0.000
R35 Polyuria	0.923	0.077	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.915	0.085	0.000
K29 Gastritis and duodenitis	0.899	0.101	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.899	0.101	0.000
K51.2 Ulcerative (chronic) proctitis	0.896	0.104	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.896	0.104	0.000
R14 Flatulence and related conditions	0.896	0.104	0.000
K21 Gastro-oesophageal reflux disease	0.891	0.109	0.000
K52 Other non-infective gastro-enteritis and colitis	0.891	0.109	0.000
Chapter VIII Diseases of the ear and mastoid process	0.886	0.114	0.000
K22.7 Barrett's oesophagus	0.883	0.117	0.000
M47 Spondylosis	0.881	0.119	0.000
K22.8 Other specified diseases of oesophagus	0.878	0.122	0.000
M75.3 Calcific tendinitis of shoulder	0.876	0.124	0.000
K04 Diseases of pulp and periapical tissues	0.875	0.125	0.000
K29.7 Gastritis, unspecified	0.868	0.132	0.000
R32 Unspecified urinary incontinence	0.865	0.135	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.863	0.137	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.863	0.137	0.000
M75.5 Bursitis of shoulder	0.860	0.140	0.000
S61 Open wound of wrist and hand	0.859	0.141	0.000
K22.9 Disease of oesophagus, unspecified	0.857	0.143	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.850	0.150	0.000
R42 Dizziness and giddiness	0.846	0.154	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.840	0.160	0.000
R79 Other abnormal findings of blood chemistry	0.840	0.160	0.000
H65-H75 Diseases of middle ear and mastoid	0.839	0.161	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.839	0.161	0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.837	0.163	0.000
K51.9 Ulcerative colitis, unspecified	0.835	0.165	0.000
K76 Other diseases of liver	0.833	0.167	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.832	0.168	0.000
K14 Diseases of tongue	0.828	0.172	0.000
A00-A09 Intestinal infectious diseases	0.826	0.174	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.824	0.176	0.000
R11 Nausea and vomiting	0.824	0.176	0.000
R47-R49 Symptoms and signs involving speech and voice	0.820	0.180	0.000
K29.4 Chronic atrophic gastritis	0.816	0.184	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.815	0.185	0.000
K50 Crohn's disease [regional enteritis]	0.812	0.188	0.000
S50-S59 Injuries to the elbow and forearm	0.809	0.191	0.000
K09 Cysts of oral region, not elsewhere classified	0.806	0.193	0.000
K11 Diseases of salivary glands	0.802	0.198	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.801	0.199	0.000
K05 Gingivitis and periodontal diseases	0.800	0.200	0.000
T66-T78 Other and unspecified effects of external causes	0.794	0.206	0.000
R45 Symptoms and signs involving emotional state	0.791	0.209	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.791	0.209	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.790	0.209	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.790	0.210	0.000
S68 Traumatic amputation of wrist and hand	0.789	0.211	0.000
M91-M94 Chondropathies	0.786	0.214	0.000
M65-M68 Disorders of synovium and tendon	0.779	0.221	0.000
M47.9 Spondylosis, unspecified	0.778	0.222	0.000
H65 Nonsuppurative otitis media	0.777	0.222	0.000
M48 Other spondylopathies	0.777	0.223	0.000
R41.3 Other amnesia	0.776	0.224	0.000
T82.1 Mechanical complication of cardiac electronic device	0.774	0.226	0.000
M75.1 Rotator cuff syndrome	0.773	0.227	0.000
S61.1 Open wound of finger(s) with damage to nail	0.771	0.229	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.771	0.229	0.000
M00-M03 Infectious arthropathies	0.770	0.230	0.000
R71 Abnormality of red blood cells	0.766	0.233	0.000
M75.0 Adhesive capsulitis of shoulder	0.766	0.234	0.000
K00 Disorders of tooth development and eruption	0.766	0.234	0.000
K70 Alcoholic liver disease	0.766	0.234	0.000
S62 Fracture at wrist and hand level	0.764	0.236	0.000
M76 Enthesopathies of lower limb, excluding foot	0.763	0.237	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.762	0.238	0.000
K51.8 Other ulcerative colitis	0.762	0.238	0.000
M46 Other inflammatory spondylopathies	0.759	0.241	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.758	0.242	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.758	0.242	0.000
K74 Fibrosis and cirrhosis of liver	0.757	0.243	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.756	0.244	0.000
Q60-Q64 Congenital malformations of the urinary system	0.756	0.244	0.000
R30 Pain associated with micturition	0.754	0.246	0.000
S60 Superficial injury of wrist and hand	0.754	0.246	0.000
K51.4 Pseudopolyposis of colon	0.752	0.248	0.000
B95-B98 Bacterial, viral and other infectious agents	0.752	0.248	0.000
M40-M43 Deforming dorsopathies	0.751	0.249	0.000
K27 Peptic ulcer, site unspecified	0.750	0.250	0.000
M80-M85 Disorders of bone density and structure	0.749	0.251	0.000
K04.7 Periapical abscess without sinus	0.749	0.251	0.000
M77 Other enthesopathies	0.742	0.258	0.000
K65-K67 Diseases of peritoneum	0.741	0.259	0.000
Chapter XXII Codes for special purposes	0.741	0.259	0.000
Chapter V Mental and behavioural disorders	0.741	0.259	0.000
K76.8 Other specified diseases of liver	0.740	0.260	0.000
K10 Other diseases of jaws	0.740	0.260	0.000
K29.2 Alcoholic gastritis	0.740	0.260	0.000
T86 Failure and rejection of transplanted organs and tissues	0.737	0.263	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.737	0.263	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.734	0.266	0.000
B25-B34 Other viral diseases	0.731	0.269	0.000
H72 Perforation of tympanic membrane	0.731	0.269	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.728	0.272	0.000
M47.8 Other spondylosis	0.728	0.272	0.000
B99-B99 Other infectious diseases	0.727	0.273	0.000
K31.7 Polyp of stomach and duodenum	0.727	0.273	0.000
M75.2 Bicipital tendinitis	0.727	0.273	0.000
T18 Foreign body in alimentary tract	0.726	0.274	0.000
A30-A49 Other bacterial diseases	0.724	0.276	0.000
K07 Dentofacial anomalies [including malocclusion]	0.724	0.276	0.000
Chapter XX External causes of morbidity and mortality	0.724	0.276	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.724	0.276	0.000
R18 Ascites	0.724	0.276	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.724	0.276	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.722	0.278	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.722	0.278	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.720	0.280	0.000
K22.5 Diverticulum of oesophagus, acquired	0.718	0.282	0.000
H65.3 Chronic mucoid otitis media	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
K28 Gastrojejunal ulcer	0.717	0.283	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
S90-S99 Injuries to the ankle and foot	0.716	0.284	0.000
T79-T79 Certain early complications of trauma	0.714	0.286	0.000
T33-T35 Frostbite	0.714	0.286	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286	0.000
T00-T07 Injuries involving multiple body regions	0.714	0.286	0.000
S10-S19 Injuries to the neck	0.714	0.286	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.714	0.286	0.000
K03 Other diseases of hard tissues of teeth	0.714	0.286	0.000
M60-M63 Disorders of muscles	0.712	0.288	0.000
R73 Elevated blood glucose level	0.712	0.288	0.000
R41.2 Retrograde amnesia	0.712	0.288	0.000
B15-B19 Viral hepatitis	0.711	0.289	0.000
K50.1 Crohn's disease of large intestine	0.711	0.289	0.000
K22.2 Oesophageal obstruction	0.711	0.289	0.000
K22.3 Perforation of oesophagus	0.710	0.290	0.000
K22.0 Achalasia of cardia	0.710	0.290	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.710	0.290	0.000
K14.8 Other diseases of tongue	0.710	0.290	0.000
K31.6 Fistula of stomach and duodenum	0.709	0.291	0.000
K31.5 Obstruction of duodenum	0.709	0.291	0.000
K31.4 Gastric diverticulum	0.709	0.291	0.000
K31.3 Pylorospasm, not elsewhere classified	0.709	0.291	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.709	0.291	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.709	0.291	0.000
K31.0 Acute dilatation of stomach	0.709	0.291	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.708	0.292	0.000
K29.1 Other acute gastritis	0.707	0.293	0.000
K51.5 Mucosal proctocolitis	0.707	0.293	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.707	0.293	0.000
E03 Other hypothyroidism	0.022	0.293	0.685
K25 Gastric ulcer	0.706	0.294	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.703	0.297	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.703	0.297	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.703	0.297	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.702	0.298	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.702	0.298	0.000
M71 Other bursopathies	0.702	0.298	0.000
M47.2 Other spondylosis with radiculopathy	0.701	0.299	0.000
R46 Symptoms and signs involving appearance and behaviour	0.699	0.301	0.000
R43 Disturbances of smell and taste	0.699	0.301	0.000
M86-M90 Other osteopathies	0.699	0.301	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.698	0.302	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.697	0.303	0.000
R12 Heartburn	0.696	0.304	0.000
T87 Complications peculiar to reattachment and amputation	0.694	0.306	0.000
B35-B49 Mycoses	0.694	0.306	0.000
R74 Abnormal serum enzyme levels	0.693	0.307	0.000
T85.2 Mechanical complication of intraocular lens	0.692	0.308	0.000
R40 Somnolence, stupor and coma	0.692	0.308	0.000
K76.6 Portal hypertension	0.691	0.309	0.000
R19.6 Halitosis	0.691	0.309	0.000
R19.3 Abdominal rigidity	0.691	0.309	0.000
R19.2 Visible peristalsis	0.691	0.309	0.000
R19.1 Abnormal bowel sounds	0.691	0.309	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.691	0.309	0.000
S67 Crushing injury of wrist and hand	0.689	0.311	0.000
S65 Injury of blood vessels at wrist and hand level	0.689	0.311	0.000
S69 Other and unspecified injuries of wrist and hand	0.689	0.311	0.000
R26 Abnormalities of gait and mobility	0.689	0.311	0.000
M75.8 Other shoulder lesions	0.688	0.312	0.000
M75.9 Shoulder lesion, unspecified	0.688	0.312	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.688	0.312	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.686	0.314	0.000
S63.6 Sprain and strain of finger(s)	0.686	0.314	0.000
M75.4 Impingement syndrome of shoulder	0.685	0.314	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.684	0.316	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.684	0.316	0.000
S40-S49 Injuries to the shoulder and upper arm	0.683	0.317	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.681	0.319	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.680	0.320	0.000
R77 Other abnormalities of plasma proteins	0.680	0.320	0.000
R76 Other abnormal immunological findings in serum	0.680	0.320	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.680	0.320	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.680	0.320	0.000
K01 Embedded and impacted teeth	0.679	0.321	0.000
M72 Fibroblastic disorders	0.679	0.321	0.000
R36 Urethral discharge	0.679	0.321	0.000
R34 Anuria and oliguria	0.679	0.321	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.678	0.322	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.678	0.322	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.678	0.322	0.000
S61.7 Multiple open wounds of wrist and hand	0.678	0.322	0.000
M49 Spondylopathies in diseases classified elsewhere	0.677	0.323	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.675	0.325	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.673	0.327	0.000
S00-S09 Injuries to the head	0.673	0.327	0.000
K72 Hepatic failure, not elsewhere classified	0.673	0.327	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.672	0.328	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.672	0.328	0.000
B65-B83 Helminthiases	0.672	0.328	0.000
B50-B64 Protozoal diseases	0.672	0.328	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.672	0.328	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.672	0.328	0.000
A80-A89 Viral infections of the central nervous system	0.672	0.328	0.000
A75-A79 Rickettsioses	0.672	0.328	0.000
A70-A74 Other diseases caused by chlamydiae	0.672	0.328	0.000
A65-A69 Other spirochaetal diseases	0.672	0.328	0.000
A20-A28 Certain zoonotic bacterial diseases	0.672	0.328	0.000
A15-A19 Tuberculosis	0.672	0.328	0.000
K77 Liver disorders in diseases classified elsewhere	0.671	0.329	0.000
K73 Chronic hepatitis, not elsewhere classified	0.671	0.329	0.000
K71 Toxic liver disease	0.671	0.329	0.000
K09.0 Developmental odontogenic cysts	0.671	0.329	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.670	0.330	0.000
M79.1 Myalgia	0.670	0.330	0.000
S70-S79 Injuries to the hip and thigh	0.669	0.331	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.668	0.332	0.000
K50.0 Crohn's disease of small intestine	0.668	0.332	0.000
K75 Other inflammatory liver diseases	0.667	0.333	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.667	0.333	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.665	0.335	0.000
S80-S89 Injuries to the knee and lower leg	0.665	0.335	0.000
M50-M54 Other dorsopathies	0.665	0.335	0.000
S51 Open wound of forearm	0.664	0.336	0.000
M47.82 Other spondylosis (Cervical region)	0.663	0.337	0.000
A08 Viral and other specified intestinal infections	0.662	0.338	0.000
K05.3 Chronic periodontitis	0.660	0.340	0.000
R49 Voice disturbances	0.660	0.340	0.000
K04.8 Radicular cyst	0.659	0.341	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.657	0.343	0.000
R17 Unspecified jaundice	0.656	0.344	0.000
R41.1 Anterograde amnesia	0.656	0.344	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.655	0.345	0.000
Q61 Cystic kidney disease	0.655	0.345	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.652	0.348	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.651	0.349	0.000
S64 Injury of nerves at wrist and hand level	0.649	0.351	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.649	0.351	0.000
K29.5 Chronic gastritis, unspecified	0.649	0.351	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.648	0.352	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.646	0.354	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.646	0.354	0.000
R45.1 Restlessness and agitation	0.646	0.354	0.000
S56 Injury of muscle and tendon at forearm level	0.645	0.355	0.000
T18.1 Foreign body in oesophagus	0.645	0.355	0.000
K02 Dental caries	0.645	0.355	0.000
K29.9 Gastroduodenitis, unspecified	0.645	0.355	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.644	0.356	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.644	0.356	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.644	0.356	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.644	0.356	0.000
R25 Abnormal involuntary movements	0.644	0.356	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.643	0.357	0.000
Q80-Q89 Other congenital malformations	0.643	0.357	0.000
Q35-Q37 Cleft lip and cleft palate	0.643	0.357	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.643	0.357	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.643	0.357	0.000
Q00-Q07 Congenital malformations of the nervous system	0.643	0.357	0.000
T68 Hypothermia	0.642	0.358	0.000
T93 Sequelae of injuries of lower limb	0.639	0.361	0.000
K52.3 Indeterminate colitis	0.639	0.361	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.639	0.361	0.000
K52.1 Toxic gastro-enteritis and colitis	0.639	0.361	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.639	0.361	0.000
S61.0 Open wound of finger(s) without damage to nail	0.639	0.361	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.638	0.362	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.637	0.362	0.000
Q50-Q56 Congenital malformations of genital organs	0.636	0.364	0.000
R27 Other lack of coordination	0.635	0.365	0.000
H90-H95 Other disorders of ear	0.635	0.365	0.000
R47 Speech disturbances, not elsewhere classified	0.634	0.366	0.000
K29.3 Chronic superficial gastritis	0.632	0.368	0.000
K11.5 Sialolithiasis	0.631	0.369	0.000
M47.1 Other spondylosis with myelopathy	0.631	0.369	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.631	0.369	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.628	0.372	0.000
K04.3 Abnormal hard tissue formation in pulp	0.627	0.373	0.000
K04.2 Pulp degeneration	0.627	0.373	0.000
K04.1 Necrosis of pulp	0.627	0.373	0.000
K04.0 Pulpitis	0.627	0.373	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.627	0.373	0.000
K22.4 Dyskinesia of oesophagus	0.626	0.374	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.626	0.374	0.000
H74 Other disorders of middle ear and mastoid	0.625	0.374	0.000
K70.3 Alcoholic cirrhosis of liver	0.623	0.377	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.622	0.378	0.000
H65.2 Chronic serous otitis media	0.622	0.378	0.000
K65 Peritonitis	0.622	0.378	0.000
H66 Suppurative and unspecified otitis media	0.622	0.378	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.621	0.378	0.000
M93 Other osteochondropathies	0.621	0.379	0.000
K82 Other diseases of gallbladder	0.621	0.379	0.000
K14.0 Glossitis	0.621	0.379	0.000
S62.6 Fracture of other finger	0.619	0.381	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.619	0.381	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.619	0.381	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.619	0.381	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.619	0.381	0.000
T82.3 Mechanical complication of other vascular grafts	0.619	0.381	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.619	0.381	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.619	0.381	0.000
K11.2 Sialoadenitis	0.618	0.382	0.000
S20-S29 Injuries to the thorax	0.617	0.383	0.000
M66 Spontaneous rupture of synovium and tendon	0.615	0.385	0.000
M67 Other disorders of synovium and tendon	0.613	0.386	0.000
M00 Pyogenic arthritis	0.611	0.389	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.610	0.389	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.610	0.390	0.000
M76.6 Achilles tendinitis	0.609	0.391	0.000
K74.6 Other and unspecified cirrhosis of liver	0.607	0.393	0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.607	0.393	0.000
M79.5 Residual foreign body in soft tissue	0.606	0.394	0.000
M80 Osteoporosis with pathological fracture	0.606	0.394	0.000
S60.8 Other superficial injuries of wrist and hand	0.605	0.395	0.000
M79.2 Neuralgia and neuritis, unspecified	0.603	0.397	0.000
H72.8 Other perforations of tympanic membrane	0.603	0.397	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.602	0.398	0.000
R79.0 Abnormal level of blood mineral	0.602	0.398	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.602	0.398	0.000
H70 Mastoiditis and related conditions	0.602	0.398	0.000
H69 Other disorders of Eustachian tube	0.602	0.398	0.000
H68 Eustachian salpingitis and obstruction	0.602	0.398	0.000
H67 Otitis media in diseases classified elsewhere	0.602	0.398	0.000
K00.6 Disturbances in tooth eruption	0.602	0.398	0.000
T19 Foreign body in genito-urinary tract	0.601	0.399	0.000
T17 Foreign body in respiratory tract	0.601	0.399	0.000
T15 Foreign body on external eye	0.601	0.399	0.000
T16 Foreign body in ear	0.601	0.399	0.000
M45 Ankylosing spondylitis	0.601	0.399	0.000
K55-K64 Other diseases of intestines	0.599	0.401	0.000
M05-M14 Inflammatory polyarthropathies	0.598	0.401	0.000
K04.6 Periapical abscess with sinus	0.598	0.402	0.000
K04.5 Chronic apical periodontitis	0.597	0.403	0.000
K76.7 Hepatorenal syndrome	0.597	0.403	0.000
K76.5 Hepatic veno-occlusive disease	0.597	0.403	0.000
K76.4 Peliosis hepatis	0.597	0.403	0.000
K76.3 Infarction of liver	0.597	0.403	0.000
K76.2 Central haemorrhagic necrosis of liver	0.597	0.403	0.000
K76.1 Chronic passive congestion of liver	0.597	0.403	0.000
T90 Sequelae of injuries of head	0.597	0.403	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.597	0.403	0.000
A49 Bacterial infection of unspecified site	0.597	0.403	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.595	0.405	0.000
S50 Superficial injury of forearm	0.594	0.406	0.000
K14.6 Glossodynia	0.594	0.406	0.000
K14.5 Plicated tongue	0.594	0.406	0.000
K14.4 Atrophy of tongue papillae	0.594	0.406	0.000
K14.3 Hypertrophy of tongue papillae	0.594	0.406	0.000
K14.2 Median rhomboid glossitis	0.594	0.406	0.000
K14.1 Geographic tongue	0.594	0.406	0.000
Q66 Congenital deformities of feet	0.593	0.407	0.000
K82.8 Other specified diseases of gallbladder	0.593	0.407	0.000
A07 Other protozoal intestinal diseases	0.592	0.408	0.000
A06 Amoebiasis	0.592	0.408	0.000
A05 Other bacterial foodborne intoxications	0.592	0.408	0.000
A03 Shigellosis	0.592	0.408	0.000
A02 Other Salmonella infections	0.592	0.408	0.000
A01 Typhoid and paratyphoid fevers	0.592	0.408	0.000
A00 Cholera	0.592	0.408	0.000
R30.0 Dysuria	0.592	0.408	0.000
R39 Other symptoms and signs involving the urinary system	0.591	0.409	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.590	0.410	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.590	0.410	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.588	0.412	0.000
T14 Injury of unspecified body region	0.588	0.412	0.000
M50 Cervical disk disorders	0.587	0.412	0.000
R45.8 Other symptoms and signs involving emotional state	0.587	0.413	0.000
M48.0 Spinal stenosis	0.587	0.413	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.586	0.414	0.000
M94 Other disorders of cartilage	0.585	0.415	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.584	0.415	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.584	0.415	0.000
K50.8 Other Crohn's disease	0.583	0.417	0.000
B34 Viral infection of unspecified site	0.583	0.417	0.000
K70.9 Alcoholic liver disease, unspecified	0.581	0.419	0.000
S59 Other and unspecified injuries of forearm	0.580	0.420	0.000
S58 Traumatic amputation of forearm	0.580	0.420	0.000
S57 Crushing injury of forearm	0.580	0.420	0.000
S55 Injury of blood vessels at forearm level	0.580	0.420	0.000
S54 Injury of nerves at forearm level	0.580	0.420	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.580	0.420	0.000
K07.3 Anomalies of tooth position	0.580	0.420	0.000
M79.19 Myalgia (Site unspecified)	0.579	0.421	0.000
T78 Adverse effects, not elsewhere classified	0.579	0.421	0.000
K09.9 Cyst of oral region, unspecified	0.578	0.422	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.578	0.422	0.000
K09.2 Other cysts of jaw	0.578	0.422	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.578	0.422	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.577	0.423	0.000
B99 Other and unspecified infectious diseases	0.576	0.424	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.576	0.424	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.576	0.424	0.000
K11.9 Disease of salivary gland, unspecified	0.575	0.425	0.000
K11.8 Other diseases of salivary glands	0.575	0.425	0.000
K11.7 Disturbances of salivary secretion	0.575	0.425	0.000
K11.6 Mucocele of salivary gland	0.575	0.425	0.000
K11.4 Fistula of salivary gland	0.575	0.425	0.000
K11.3 Abscess of salivary gland	0.575	0.425	0.000
K11.1 Hypertrophy of salivary gland	0.575	0.425	0.000
K11.0 Atrophy of salivary gland	0.575	0.425	0.000
S63.1 Dislocation finger	0.574	0.426	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.574	0.426	0.000
S63.5 Sprain and strain of wrist	0.574	0.426	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.574	0.426	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.574	0.426	0.000
S63.2 Multiple dislocations of fingers	0.574	0.426	0.000
S63.0 Dislocation of wrist	0.574	0.426	0.000
K05.2 Acute periodontitis	0.573	0.426	0.000
K05.6 Periodontal disease, unspecified	0.573	0.426	0.000
K05.5 Other periodontal diseases	0.573	0.426	0.000
K05.4 Periodontosis	0.573	0.426	0.000
K05.1 Chronic gingivitis	0.573	0.426	0.000
K05.0 Acute gingivitis	0.573	0.426	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.573	0.426	0.000
K74.3 Primary biliary cirrhosis	0.573	0.427	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.573	0.427	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.572	0.427	0.000
R30.9 Painful micturition, unspecified	0.572	0.428	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.571	0.429	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.571	0.429	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.570	0.429	0.000
M77.1 Lateral epicondylitis	0.569	0.430	0.000
T75 Effects of other external causes	0.569	0.431	0.000
T74 Maltreatment syndromes	0.569	0.431	0.000
T73 Effects of other deprivation	0.569	0.431	0.000
T70 Effects of air pressure and water pressure	0.569	0.431	0.000
T69 Other effects of reduced temperature	0.569	0.431	0.000
T67 Effects of heat and light	0.569	0.431	0.000
T71 Asphyxiation	0.569	0.431	0.000
T66 Unspecified effects of radiation	0.569	0.431	0.000
H73 Other disorders of tympanic membrane	0.569	0.431	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.569	0.431	0.000
R44.3 Hallucinations, unspecified	0.567	0.433	0.000
R45.7 State of emotional shock and stress, unspecified	0.567	0.433	0.000
R45.6 Physical violence	0.567	0.433	0.000
R45.5 Hostility	0.567	0.433	0.000
R45.4 Irritability and anger	0.567	0.433	0.000
R45.3 Demoralisation and apathy	0.567	0.433	0.000
R45.2 Unhappiness	0.567	0.433	0.000
R45.0 Nervousness	0.567	0.433	0.000
T98 Sequelae of other and unspecified effects of external causes	0.567	0.433	0.000
T95 Sequelae of burns, corrosions and frostbite	0.567	0.433	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.567	0.433	0.000
T91 Sequelae of injuries of neck and trunk	0.567	0.433	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.567	0.433	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.567	0.433	0.000
M99 Biomechanical lesions, not elsewhere classified	0.567	0.433	0.000
M43 Other deforming dorsopathies	0.567	0.433	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.566	0.434	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.566	0.434	0.000
S68.4 Traumatic amputation of hand at wrist level	0.566	0.434	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.566	0.434	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.566	0.434	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.566	0.434	0.000
M79.7 Fibromyalgia	0.566	0.434	0.000
Y52 Agents primarily affecting the cardiovascular system	0.566	0.434	0.000
R73.0 Abnormal glucose tolerance test	0.566	0.434	0.000
W50-W64 Exposure to animate mechanical forces	0.565	0.434	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.564	0.436	0.000
M92 Other juvenile osteochondrosis	0.563	0.436	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.563	0.436	0.000
K12 Stomatitis and related lesions	0.563	0.437	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations