TreeWAS – Variant ID: rs4713858

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.026	0.974	0.000
N81.2 Incomplete uterovaginal prolapse	0.024	0.976	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.023	0.977	0.000
O42.9 Premature rupture of membranes, unspecified	0.023	0.977	0.000
O42 Premature rupture of membranes	0.022	0.978	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.020	0.980	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.986	0.014
O42.2 Premature rupture of membranes, labour delayed by therapy	0.014	0.986	0.000
D12.2 Ascending colon	0.000	0.987	0.013
Z45.0 Adjustment and management of cardiac pacemaker	0.011	0.989	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.989	0.011
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.990	0.010
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.992	0.008
M23.8 Other internal derangements of knee	0.008	0.992	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.992	0.008
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.992	0.008
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.992	0.007
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.992	0.008
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.993	0.007
S02.4 Fracture of malar and maxillary bones	0.000	0.993	0.007
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.007	0.993	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.993	0.007
N60.2 Fibroadenosis of breast	0.000	0.993	0.007
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.993	0.007
A49.0 Staphylococcal infection, unspecified	0.007	0.993	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.007	0.993	0.000
H33.2 Serous retinal detachment	0.006	0.994	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.006	0.994	0.000
A49.9 Bacterial infection, unspecified	0.006	0.994	0.000
N60 Benign mammary dysplasia	0.000	0.994	0.006
A49 Bacterial infection of unspecified site	0.006	0.994	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.006	0.994	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.994	0.006
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.005	0.994	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.995	0.005
M23.80 Other internal derangements of knee (Multiple sites)	0.005	0.995	0.000
N43.3 Hydrocele, unspecified	0.000	0.995	0.005
N60.4 Mammary duct ectasia	0.000	0.995	0.005
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.995	0.005
S02.60 Fracture of mandible (closed)	0.000	0.995	0.005
N60.3 Fibrosclerosis of breast	0.000	0.995	0.005
N60.8 Other benign mammary dysplasias	0.000	0.995	0.005
M31.6 Other giant cell arteritis	0.005	0.995	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.995	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.005	0.995	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.995	0.005
S02.6 Fracture of mandible	0.000	0.995	0.005
H53.8 Other visual disturbances	0.005	0.995	0.000
A49.1 Streptococcal infection, unspecified	0.005	0.995	0.000
Q63.0 Accessory kidney	0.005	0.995	0.000
K82.8 Other specified diseases of gallbladder	0.000	0.996	0.004
S02 Fracture of skull and facial bones	0.000	0.996	0.004
A49.3 Mycoplasma infection, unspecified	0.004	0.996	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.996	0.004
T31.0 Burns involving less than 10% of body surface	0.000	0.996	0.004
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.996	0.004
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q18 Other congenital malformations of face and neck	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.996	0.004
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
F45.8 Other somatoform disorders	0.004	0.996	0.000
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
A49.8 Other bacterial infections of unspecified site	0.004	0.996	0.000
M05.2 Rheumatoid vasculitis	0.000	0.996	0.004
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.996	0.004
R76.8 Other specified abnormal immunological findings in serum	0.000	0.996	0.004
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.996	0.004
Q18.1 Preauricular sinus and cyst	0.004	0.996	0.000
S02.3 Fracture of orbital floor	0.000	0.996	0.004
S02.61 Fracture of mandible (open)	0.000	0.996	0.004
M31 Other necrotising vasculopathies	0.004	0.996	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.996	0.004
N43 Hydrocele and spermatocele	0.000	0.996	0.004
M05.0 Felty's syndrome	0.000	0.996	0.003
Q63.1 Lobulated, fused and horseshoe kidney	0.003	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.997	0.003
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
N43.4 Spermatocele	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
M05.1 Rheumatoid lung disease	0.000	0.997	0.003
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
M31.9 Necrotising vasculopathy, unspecified	0.003	0.997	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.997	0.003
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.997	0.003
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M31.0 Hypersensitivity angiitis	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
S02.5 Fracture of tooth	0.000	0.997	0.003
M31.4 Aortic arch syndrome [Takayasu]	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.997	0.003
S02.30 Fracture of orbital floor (closed)	0.000	0.997	0.003
Q18.9 Congenital malformation of face and neck, unspecified	0.003	0.997	0.000
Q18.8 Other specified congenital malformations of face and neck	0.003	0.997	0.000
Q18.7 Microcheilia	0.003	0.997	0.000
Q18.6 Macrocheilia	0.003	0.997	0.000
Q18.5 Microstomia	0.003	0.997	0.000
Q18.4 Macrostomia	0.003	0.997	0.000
Q18.3 Webbing of neck	0.003	0.997	0.000
Q18.2 Other branchial cleft malformations	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.000	0.997	0.003
N87.0 Mild cervical dysplasia	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.997	0.003
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
I45.9 Conduction disorder, unspecified	0.003	0.997	0.000
N50.1 Vascular disorders of male genital organs	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
M31.7 Microscopic polyangiitis	0.003	0.997	0.000
N43.2 Other hydrocele	0.000	0.997	0.003
N43.1 Infected hydrocele	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.003
M05.28 Rheumatoid vasculitis (Other)	0.000	0.997	0.003
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.997	0.003
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.997	0.003
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.997	0.003
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.997	0.003
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.997	0.003
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.997	0.003
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.997	0.003
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.997	0.003
S02.1 Fracture of base of skull	0.000	0.997	0.003
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.997	0.003
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.997	0.003
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.997	0.003
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.997	0.003
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.997	0.003
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.997	0.003
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.997	0.003
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.997	0.003
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.997	0.003
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.997	0.003
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.997	0.003
S02.31 Fracture of orbital floor (open)	0.000	0.997	0.003
M31.2 Lethal midline granuloma	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.997	0.003
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.997	0.003
Q24.0 Dextrocardia	0.003	0.997	0.000
M05.08 Felty's syndrome (Other)	0.000	0.997	0.003
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.997	0.003
M05.06 Felty's syndrome (Lower leg)	0.000	0.997	0.003
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.997	0.003
M05.04 Felty's syndrome (Hand)	0.000	0.997	0.003
M05.03 Felty's syndrome (Forearm)	0.000	0.997	0.003
M05.02 Felty's syndrome (Upper arm)	0.000	0.997	0.003
M05.01 Felty's syndrome (Shoulder region)	0.000	0.997	0.003
M05.00 Felty's syndrome (Multiple sites)	0.000	0.997	0.003
N43.0 Encysted hydrocele	0.000	0.997	0.003
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.997	0.003
M05.09 Felty's syndrome (Site unspecified)	0.000	0.997	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.997	0.003
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
M31.8 Other specified necrotising vasculopathies	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
M05.18 Rheumatoid lung disease (Other)	0.000	0.997	0.002
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.997	0.002
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.997	0.002
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.997	0.002
M05.14 Rheumatoid lung disease (Hand)	0.000	0.997	0.002
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.997	0.002
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.997	0.002
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.997	0.002
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.997	0.002
Q17.5 Prominent ear	0.002	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.997	0.000
S02.51 Fracture of tooth (open)	0.000	0.997	0.002
M31.1 Thrombotic microangiopathy	0.002	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.997	0.000
M31.3 Wegener's granulomatosis	0.002	0.997	0.000
Q24.6 Congenital heart block	0.002	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.997	0.002
Q24.8 Other specified congenital malformations of heart	0.002	0.997	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.997	0.002
Q22.5 Ebstein's anomaly	0.002	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
Q12 Congenital lens malformations	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
I45 Other conduction disorders	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
R76 Other abnormal immunological findings in serum	0.000	0.998	0.002
T31 Burns classified according to extent of body surface involved	0.000	0.998	0.002
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q15.0 Congenital glaucoma	0.002	0.998	0.000
Q17.9 Congenital malformation of ear, unspecified	0.002	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.998	0.000
Q17.4 Misplaced ear	0.002	0.998	0.000
Q17.3 Other misshapen ear	0.002	0.998	0.000
Q17.2 Microtia	0.002	0.998	0.000
Q17.1 Macrotia	0.002	0.998	0.000
Q17.0 Accessory auricle	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.000	0.998	0.002
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
F45 Somatoform disorders	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.002	0.998	0.000
Q15.9 Congenital malformation of eye, unspecified	0.002	0.998	0.000
Q15.8 Other specified congenital malformations of eye	0.002	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
Q16.5 Congenital malformation of inner ear	0.002	0.998	0.000
Q16.4 Other congenital malformations of middle ear	0.002	0.998	0.000
Q16.3 Congenital malformation of ear ossicles	0.002	0.998	0.000
Q16.2 Absence of eustachian tube	0.002	0.998	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.002	0.998	0.000
Q16.0 Congenital absence of (ear) auricle	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
K60.2 Anal fissure, unspecified	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
Q11.3 Macrophthalmos	0.002	0.998	0.000
Q11.2 Microphthalmos	0.002	0.998	0.000
Q11.1 Other anophthalmos	0.002	0.998	0.000
Q11.0 Cystic eyeball	0.002	0.998	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.002	0.998	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q13.5 Blue sclera	0.002	0.998	0.000
Q13.4 Other congenital corneal malformations	0.002	0.998	0.000
Q13.3 Congenital corneal opacity	0.002	0.998	0.000
Q13.2 Other congenital malformations of iris	0.002	0.998	0.000
Q13.1 Absence of iris	0.002	0.998	0.000
Q13.0 Coloboma of iris	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
S06.3 Focal brain injury	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
I45.0 Right fascicular block	0.002	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.002	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q14.3 Congenital malformation of choroid	0.002	0.998	0.000
Q14.2 Congenital malformation of optic disk	0.002	0.998	0.000
Q14.0 Congenital malformation of vitreous humour	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.002	0.998	0.000
H18.6 Keratoconus	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
E11.3 With ophthalmic complications	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.998	0.002
I45.5 Other specified heart block	0.002	0.998	0.000
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q31.3 Laryngocele	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
Q31.0 Web of larynx	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Q62.2 Congenital megaloureter	0.002	0.998	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
S00.8 Superficial injury of other parts of head	0.000	0.998	0.002
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
Q12.9 Congenital lens malformation, unspecified	0.002	0.998	0.000
Q12.8 Other congenital lens malformations	0.002	0.998	0.000
Q12.4 Spherophakia	0.002	0.998	0.000
Q12.3 Congenital aphakia	0.002	0.998	0.000
Q12.2 Coloboma of lens	0.002	0.998	0.000
Q12.1 Congenital displaced lens	0.002	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.998	0.000
Q62.6 Malposition of ureter	0.002	0.998	0.000
Q62.4 Agenesis of ureter	0.002	0.998	0.000
Q62.0 Congenital hydronephrosis	0.002	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.998	0.000
S06.0 Concussion	0.000	0.998	0.002
Q90 Down's syndrome	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.002	0.998	0.000
Q62.5 Duplication of ureter	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
R76.2 False-positive serological test for syphilis	0.000	0.998	0.002
R76.1 Abnormal reaction to tuberculin test	0.000	0.998	0.002
T31.9 Burns involving 90% or more of body surface	0.000	0.998	0.002
T31.8 Burns involving 80-89% of body surface	0.000	0.998	0.002
T31.7 Burns involving 70-79% of body surface	0.000	0.998	0.002
T31.6 Burns involving 60-69% of body surface	0.000	0.998	0.002
T31.5 Burns involving 50-59% of body surface	0.000	0.998	0.002
T31.4 Burns involving 40-49% of body surface	0.000	0.998	0.002
T31.3 Burns involving 30-39% of body surface	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.002	0.998	0.001
Q36 Cleft lip	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
R76.0 Raised antibody titer	0.000	0.998	0.002
T31.1 Burns involving 10-19% of body surface	0.000	0.998	0.002
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.998	0.002
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.002	0.998	0.000
Q31.8 Other congenital malformations of larynx	0.002	0.998	0.000
Q31.5 Congenital laryngomalacia	0.002	0.998	0.000
Q31.4 Congenital laryngeal stridor	0.002	0.998	0.000
Q31.2 Laryngeal hypoplasia	0.002	0.998	0.000
Q31.1 Congenital subglottic stenosis	0.002	0.998	0.000
Z82.3 Family history of stroke	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
M84.22 Delayed union of fracture (Upper arm)	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
T31.2 Burns involving 20-29% of body surface	0.000	0.998	0.002
F45.2 Hypochondriacal disorder	0.002	0.998	0.000
I45.2 Bifascicular block	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.002	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.002	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.002	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
Q04 Other congenital malformations of brain	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.000	0.998	0.002
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations